Ravages: Rare Variant Analysis and Genetic Simulations

Rare variant association tests: burden tests (Bocher et al. 2019 <doi:10.1002/gepi.22210>) and the Sequence Kernel Association Test (Bocher et al. 2021 <doi:10.1038/s41431-020-00792-8>) in the whole genome using the RAVA-FIRST approach (Bocher et al. 2022 <doi:10.1371/journal.pgen.1009923>). Ravages also enables to perform genetic simulations (Bocher et al. 2023 <doi:10.1002/gepi.22529>).

Version: 1.2.0
Depends: R (≥ 3.5.0), Rcpp, RcppParallel, methods, gaston, mlogit (≥ 1.1-0)
Imports: Formula, dfidx, parallel, bedr, curl, data.table
LinkingTo: Rcpp, RcppParallel, RcppEigen, gaston, BH
Suggests: knitr, rmarkdown
Published: 2026-02-27
DOI: 10.32614/CRAN.package.Ravages
Author: Ozvan Bocher [aut, cre], Hervé Perdry [aut], Gaelle Marenne [aut]
Maintainer: Ozvan Bocher <ozvan.bocher at univ-brest.fr>
License: GPL-3
NeedsCompilation: yes
Materials: NEWS
CRAN checks: Ravages results

Documentation:

Reference manual: Ravages.html , Ravages.pdf
Vignettes: "Ravages_Simulations" (source, R code)
Ravages_Association (source, R code)

Downloads:

Package source: Ravages_1.2.0.tar.gz
Windows binaries: r-devel: Ravages_1.1.3.zip, r-release: Ravages_1.1.3.zip, r-oldrel: Ravages_1.1.3.zip
macOS binaries: r-release (arm64): Ravages_1.2.0.tgz, r-oldrel (arm64): Ravages_1.2.0.tgz, r-release (x86_64): Ravages_1.1.3.tgz, r-oldrel (x86_64): Ravages_1.1.3.tgz
Old sources: Ravages archive

Linking:

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