simpleSimulate {splatter} | R Documentation |
Simulate counts from a simple negative binomial distribution without simulated library sizes, differential expression etc.
simpleSimulate(params = newSimpleParams(), verbose = TRUE, ...)
params |
SimpleParams object containing simulation parameters. |
verbose |
logical. Whether to print progress messages |
... |
any additional parameter settings to override what is provided in
|
Gene means are simulated from a gamma distribution with
shape = mean.shape
and rate = mean.rate
. Counts are then
simulated from a negative binomial distribution with mu = means
and
size = 1 / counts.disp
. See SimpleParams
for more
details of the parameters.
SingleCellExperiment containing simulated counts
sim <- simpleSimulate() # Override default parameters sim <- simpleSimulate(nGenes = 1000, nCells = 50)