mfaSimulate {splatter} | R Documentation |
Simulate a bifurcating pseudotime path using the mfa method.
mfaSimulate(params = newMFAParams(), verbose = TRUE, ...)
params |
MFAParams object containing simulation parameters. |
verbose |
Logical. Whether to print progress messages. |
... |
any additional parameter settings to override what is provided in
|
This function is just a wrapper around create_synthetic
that takes a MFAParams
, runs the simulation then converts the
output from log-expression to counts and returns a
SingleCellExperiment
object. See
create_synthetic
and the mfa paper for more details about
how the simulation works.
SingleCellExperiment containing simulated counts
Campbell KR, Yau C. Probabilistic modeling of bifurcations in single-cell gene expression data using a Bayesian mixture of factor analyzers. Wellcome Open Research (2017).
Paper: 10.12688/wellcomeopenres.11087.1
Code: https://github.com/kieranrcampbell/mfa
sim <- mfaSimulate()