SWATH2stats-package {SWATH2stats}R Documentation

SWATH2stats

Description

This package is intended to transform SWATH data from the OpenSWATH software into a format readable by other statistics packages while performing filtering, annotation and FDR assessment.

Details

Package: SWATH2stats
Type: Package
Version: 1.13.6
Date: 2019-04-28
License: GPLv3

Author(s)

Peter Blattmann, Moritz Heusel and Ruedi Aebersold

Maintainer: Peter Blattmann <blattmann@imsb.biol.ethz.ch>

References

Blattmann P, Heusel M, Aebersold R. SWATH2stats: An R/Bioconductor Package to Process and Convert Quantitative SWATH-MS Proteomics Data for Downstream Analysis Tools. PLoS ONE 11(4): e0153160 (2016). doi: 10.1371/journal.pone.0153160.

Rost HL, Rosenberger G, Navarro P, Gillet L, Miladinovic SM, Schubert OT, Wolski W, Collins BC, Malmstrom J, Malmstrom L, Aebersold R. OpenSWATH enables automated, targeted analysis of data-independent acquisition MS data. Nature Biotechnology. 2014 Mar;32(3):219-23. doi: 10.1038/nbt.2841.

Choi M, Chang CY, Clough T, Broudy D, Killeen T, MacLean B, Vitek O. MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments.Bioinformatics. 2014 Sep 1;30(17):2524-6. doi: 10.1093/bioinformatics/btu305.

Rosenberger G, Ludwig C, Rost HL, Aebersold R, Malmstrom L. aLFQ: an R-package for estimating absolute protein quantities from label-free LC-MS/MS proteomics data. Bioinformatics. 2014 Sep 1;30(17):2511-3. doi: 10.1093/bioinformatics/btu200.

Suomi T., Corthals G., Nevalainen O.S., and Elo L.L. (2015). Using Peptide-Level Proteomics Data for Detecting Differentially Expressed Proteins. J Proteome Res. Nov 6;14(11):4564-70. doi: 10.1021/acs.jproteome.5b00363.

Suomi, T. and Elo L.L. (2017). Enhanced differential expression statistics for data-independent acquisition proteomics" Scientific Reports 7, Article number: 5869.doi:10.1038/s41598-017-05949-y


[Package SWATH2stats version 1.14.0 Index]