centBloodSub.m {EpiDISH} | R Documentation |
This reference is a subset of centDHSbloodDMC.m
. This referencen contains 188
DMCs which exhibit similar median DNAm values across epithelial, fibroblast
and ICs to ensure that the estimation of IC subtype fractions is not
confounded by the epithelial and fibroblast cells in the sample.
data(centBloodSub.m)
A matrix with 188 rows and 7 columns
B-cells
CD4+ T-cells
CD8+ T-cells
NK-cells
Monocytes
Neutrophils
Eosinophils
Zheng SC, Webster AP, Dong D, Feber A, Graham DG, Sullivan R, Jevons S, Lovat LB, Beck S, Widschwendter M, Teschendorff AE A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix. Epigenomics (2018) 10: 925-940. doi: 10.2217/epi-2018-0037.
Teschendorff AE, Breeze CE, Zheng SC, Beck S. A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies. BMC Bioinformatics (2017) 18: 105. doi: 10.1186/s12859-017-1511-5.
Reinius LE, Acevedo N, Joerink M, Pershagen G, Dahlen S-E, Greco D, Soderhall C, Scheynius A, Kere J. Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility. PLoS ONE (2012) 7: e41361. doi: 10.1371/journal.pone.0041361.