DNABarcodeCompatibility-package {DNABarcodeCompatibility}R Documentation

DNABarcodeCompatibility: to find least-redundant sets of compatible barcodes for multiplex experiments performed on next generation sequencing platforms.

Description

The DNABarcodeCompatibility package provides six functions to load DNA barcodes, and to generate, filter and optimize sets of barcode combinations for multiplex sequencing experiments. In particular, barcode combinations are selected to be compatible with respect to Illumina chemistry constraints, and can be filtered to keep those that are robust against substitution and insertion/deletion errors thereby facilitating the demultiplexing step. In addition, the package provides an optimizer function to further favor the selection of compatible barcode combinations with least redundancy of DNA barcodes.


[Package DNABarcodeCompatibility version 1.0.0 Index]