splatSimDropout {splatter} | R Documentation

## Simulate dropout

### Description

A logistic function is used to form a relationshop between the expression level of a gene and the probability of dropout, giving a probability for each gene in each cell. These probabilities are used in a Bernoulli distribution to decide which counts should be dropped.

### Usage

    splatSimDropout(sim, params)

### Arguments

`sim` | SingleCellExperiment to add dropout to.
`params` | SplatParams object with simulation parameters.

### Value

SingleCellExperiment with simulated dropout and observed counts.

[Package splatter version 1.2.2 Index]