DATE.ADDED.TO.CATALOG	PUBMEDID	FIRST.AUTHOR	DATE	JOURNAL	LINK	STUDY	DISEASE.TRAIT	INITIAL.SAMPLE.SIZE	REPLICATION.SAMPLE.SIZE	REGION	CHR_ID	CHR_POS	REPORTED.GENE.S.	MAPPED_GENE	UPSTREAM_GENE_ID	DOWNSTREAM_GENE_ID	SNP_GENE_IDS	UPSTREAM_GENE_DISTANCE	DOWNSTREAM_GENE_DISTANCE	STRONGEST.SNP.RISK.ALLELE	SNPS	MERGED	SNP_ID_CURRENT	CONTEXT	INTERGENIC	RISK.ALLELE.FREQUENCY	P.VALUE	PVALUE_MLOG	P.VALUE..TEXT.	OR.or.BETA	X95..CI..TEXT.	PLATFORM..SNPS.PASSING.QC.	CNV
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	13q14.11	13	43883789	C13orf31	LACC1			ENSG00000179630	NA	NA	rs3764147-G	rs3764147	0	3764147	missense_variant	0	0.245	1e-10	10		1.17	[1.12-1.23]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	16p12.1	16	28479196	IL27, SH2B1, EIF3C, LAT, CD19	CLN3, AC138894.1			ENSG00000188603, ENSG00000261832	NA	NA	rs151181-G	rs151181	0	151181	intron_variant	0	0.386	2e-11	10.698970004336		1.07	[1.03-1.12]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	10q22.3	10	79300560	ZMIZ1	ZMIZ1			ENSG00000108175	NA	NA	rs1250550-G	rs1250550	0	1250550	intron_variant	0	0.669	1e-30	30		1.19	[1.15-1.23]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	14q24.1	14	68743482	ZFP36L1	AL132986.1 - ZFP36L1	ENSG00000287913	ENSG00000185650		6804	44178	rs4902642-G	rs4902642	0	4902642	regulatory_region_variant	1	0.584	2e-10	9.69897000433602		1.07	[1.11-1.04]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q33.3	5	159360377	IL12B	AC008691.1			ENSG00000249738	NA	NA	rs6556412-A	rs6556412	0	6556412	intron_variant	0	0.332	5e-14	13.301029995664		1.18	[1.13-1.24]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	10q21.1	10	58153390	UBE2D1	AC026884.1 - IPMK	ENSG00000232115	ENSG00000151151		46511	38127	rs1819658-C	rs1819658	0	1819658	regulatory_region_variant	1	0.774	9e-17	16.0457574905607		1.19	[1.13-1.25]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1q32.1	1	206766559	IL10, IL19	Y_RNA - IL10	ENSG00000265852	ENSG00000136634		18467	1043	rs3024505-T	rs3024505	0	3024505	intergenic_variant	1	0.157	2e-14	13.698970004336		1.12	[1.07-1.17]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1q24.3	1	172884320	TNFSF18, TNFSF4, FASLG	AL031599.1			ENSG00000224228	NA	NA	rs7517810-T	rs7517810	0	7517810	intron_variant	0	0.246	2e-15	14.698970004336		1.22	[1.16-1.28]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	21q22.3	21	44195140	ICOSLG	GATD3A			ENSG00000160221	NA	NA	rs2838519-G	rs2838519	0	2838519	intron_variant	0	0.391	2e-14	13.698970004336		1.18	[1.13-1.23]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	13q14.11	13	42478744	TNFSF11	LINC02341			ENSG00000283554	NA	NA	rs2062305-G	rs2062305	0	2062305	intron_variant	0	0.346	5e-10	9.30102999566398		1.1	[1.05-1.15]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	19p13.3	19	1124836	GPX4, SBNO2	SBNO2, SBNO2			ENSG00000064932, ENSG00000278788	NA	NA	rs740495-G	rs740495	0	740495	intron_variant	0	0.247	8e-12	11.0969100130081		1.16	[1.10-1.21]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2p23.3	2	27519736	GCKR	GCKR			ENSG00000084734	NA	NA	rs780093-T	rs780093	0	780093	intron_variant	0	0.418	5e-11	10.301029995664		1.15	[1.10-1.21]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2q37.1	2	230252159	SP140	SP140			ENSG00000079263	NA	NA	rs7423615-T	rs7423615	0	7423615	intron_variant	0	0.187	3e-13	12.5228787452803		1.12	[1.07-1.18]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	15q22.33	15	67150258	SMAD3	SMAD3			ENSG00000166949	NA	NA	rs17293632-T	rs17293632	0	17293632	intron_variant	0	0.233	3e-19	18.5228787452803		1.12	[1.07-1.16]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	11q12.2	11	61790331	FADS1	TMEM258			ENSG00000134825	NA	NA	rs102275-C	rs102275	0	102275	non_coding_transcript_exon_variant	0	0.341	2e-11	10.698970004336		1.08	[1.04-1.12]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1q22	1	155260340	SCAMP3, MUC1	SCAMP3			ENSG00000116521	NA	NA	rs3180018-A	rs3180018	1	1142287	synonymous_variant	0	0.25	2e-13	12.698970004336		1.13	[1.06-1.19]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2p23.3	2	25269598	DNMT3A	DNMT3A			ENSG00000119772	NA	NA	rs13428812-G	rs13428812	0	13428812	intron_variant	0	0.326	9e-10	9.04575749056067		1.06	[1.03-1.10]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	12q12	12	40398498	MUC19, LRRK2	MUC19, AC107023.1			ENSG00000205592, ENSG00000258167	NA	NA	rs11564258-A	rs11564258	0	11564258	intron_variant	0	0.025	6e-21	20.2218487496164		1.74	[1.55-1.95]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	22q12.2	22	30196498	MTMR3	AC002378.1			ENSG00000225676	NA	NA	rs713875-C	rs713875	0	713875	intron_variant	0	0.471	7e-12	11.1549019599857		1.08	[1.04-1.13]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q35.2	5	173852839	CPEB4	LINC01485 - CPEB4	ENSG00000254211	ENSG00000113742		43800	35510	rs359457-T	rs359457	0	359457	intergenic_variant	1	0.571	3e-12	11.5228787452803		1.08	[1.04-1.12]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	17q21.2	17	42418754	STAT3, MLX	CAVIN1			ENSG00000177469	NA	NA	rs11871801-A	rs11871801	0	11871801	intron_variant	0	0.756	3e-08	7.52287874528034		1.15	[1.10-1.21]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6q27	6	166993145	CCR6	Z94721.1			ENSG00000227598	NA	NA	rs415890-C	rs415890	0	415890	intron_variant	0	0.522	3e-12	11.5228787452803		1.17	[1.12-1.22]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	9q34.3	9	136372044	CARD9, SNAPC4	CARD9			ENSG00000187796	NA	NA	rs4077515-T	rs4077515	0	4077515	missense_variant	0	0.411	1e-36	36		1.18	[1.13-1.22]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2p16.1	2	60997124	REL, C2orf74	PUS10			ENSG00000162927	NA	NA	rs10181042-T	rs10181042	0	10181042	intron_variant	0	0.42	7e-09	8.15490195998574		1.14	[1.09-1.19]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1q32.1	1	200908434	C1orf106, KIF21B	INAVA			ENSG00000163362	NA	NA	rs7554511-C	rs7554511	0	7554511	intron_variant	0	0.726	2e-07	6.69897000433602		1.14	[1.08-1.19]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	9p24.1	9	4981602	JAK2	HNRNPA1P41 - JAK2	ENSG00000220937	ENSG00000096968		35700	2788	rs10758669-C	rs10758669	0	10758669	intergenic_variant	1	0.349	1e-13	13		1.18	[1.13-1.23]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q33.1	5	150890858	IRGM	IRGM			ENSG00000237693	NA	NA	rs7714584-G	rs7714584	0	7714584	intron_variant	0	0.088	8e-19	18.0969100130081		1.37	[1.28-1.47]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	10p15.1	10	6060049	IL2RA	IL2RA			ENSG00000134460	NA	NA	rs12722489-C	rs12722489	0	12722489	intron_variant	0	0.852	3e-09	8.52287874528034		1.11	[1.05-1.16]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	10q21.2	10	62685804	ZNF365	AC067751.1			ENSG00000238280	NA	NA	rs10761659-G	rs10761659	0	10761659	intron_variant	0	0.538	4e-22	21.397940008672		1.23	[1.18-1.29]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1p31.3	1	67240275	IL23R	IL23R			ENSG00000162594	NA	NA	rs11209026-G	rs11209026	0	11209026	missense_variant	0	0.932	1e-64	64		2.66	[2.36-3.00]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2q12.1	2	102437989	IL12RL2, IL18R1, IL1RL1, IL18RAP	IL18RAP			ENSG00000115607	NA	NA	rs2058660-G	rs2058660	0	2058660	intron_variant	0	0.231	2e-12	11.698970004336		1.19	[1.14-1.26]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	22q11.21	22	21574352	YDJC	UBE2L3			ENSG00000185651	NA	NA	rs181359-T	rs181359	0	181359	intron_variant	0	0.203	5e-16	15.301029995664		1.1	[1.06-1.15]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1p36.23	1	7819003	VAMP3	PER3, Z98884.1			ENSG00000049246, ENSG00000236266	NA	NA	rs2797685-A	rs2797685	0	2797685	intron_variant	0	0.19	7e-09	8.15490195998574		1.05	[1.01-1.10]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	19p13.2	19	10359299	ICAM3, TYK2, ICAM1	TYK2			ENSG00000105397	NA	NA	rs12720356-G	rs12720356	0	12720356	missense_variant	0	0.084	1e-12	12		1.12	[1.06-1.19]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	7p12.2	7	50264865	ZPBP, IKZF1, FIGNL1	AC020743.2 - AC020743.3	ENSG00000231681	ENSG00000235620		1871	9925	rs1456896-T	rs1456896	0	1456896	regulatory_region_variant	1	0.69	1e-08	8		1.14	[1.09-1.20]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	9q32	9	114790605	TNFSF8, TNFSF15	TNFSF15			ENSG00000181634	NA	NA	rs3810936-C	rs3810936	0	3810936	synonymous_variant	0	0.682	1e-15	15		1.21	[1.15-1.27]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	17q21.1	17	39884510	IKZF3, GSMDL, ZPBP2, ORMDL3	ZPBP2 - GSDMB	ENSG00000186075	ENSG00000073605		6614	20085	rs2872507-A	rs2872507	0	2872507	intergenic_variant	1	0.458	2e-09	8.69897000433602		1.14	[1.09-1.19]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2p21	2	43579779	THADA	THADA			ENSG00000115970	NA	NA	rs10495903-T	rs10495903	0	10495903	intron_variant	0	0.129	2e-14	13.698970004336		1.14	[1.09-1.20]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6q25.3	6	159069404	TAGAP	AL035530.1, AL035530.2, AL356417.3			ENSG00000226032, ENSG00000271913, ENSG00000285492	NA	NA	rs212388-G	rs212388	0	212388	intron_variant	0	0.393	2e-11	10.698970004336		1.1	[1.05-1.14]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	14q31.3	14	88006251	GALC, GPR65	GPR65			ENSG00000140030	NA	NA	rs8005161-T	rs8005161	0	8005161	intron_variant	0	0.119	4e-18	17.397940008672		1.23	[1.16-1.31]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	19q13.33	19	48711017	FUT2, RASIP1	FUT2 - MAMSTR	ENSG00000176920	ENSG00000176909		5066	1708	rs281379-A	rs281379	0	281379	intergenic_variant	1	0.487	7e-12	11.1549019599857		1.07	[1.04-1.11]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q31.1	5	132448701	IL3, IRF1, SLC22A5, SLC22A4	C5orf56, AC116366.3			ENSG00000197536, ENSG00000283782	NA	NA	rs12521868-T	rs12521868	0	12521868	intron_variant	0	0.422	1e-20	20		1.23	[1.18-1.28]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q15	5	96908845	ERAP2, LRAP	AC009126.1, ERAP2			ENSG00000247121, ENSG00000164308	NA	NA	rs2549794-C	rs2549794	0	2549794	intron_variant	0	0.409	1e-10	10		1.05	[1.02-1.09]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	20q13.33	20	63718234	SLC2A4RG, TNFRS-F6B, RTEL1	AL121845.3, ZGPAT			ENSG00000273154, ENSG00000197114	NA	NA	rs4809330-G	rs4809330	0	4809330	intron_variant	0	0.709	3e-15	14.5228787452803		1.12	[1.06-1.18]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1q31.3	1	197758512	DENND1B	AL365258.1, DENND1B			ENSG00000224901, ENSG00000213047	NA	NA	rs1998598-G	rs1998598	0	1998598	intron_variant	0	0.302	9e-09	8.04575749056067		1.04	[1.00-1.09]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	10p11.21	10	35246767	CREM	RNU6-794P - CCNY	ENSG00000253070	ENSG00000108100		15373	258	rs12242110-G	rs12242110	0	12242110	intergenic_variant	1	0.315	1e-09	9		1.15	[1.10-1.20]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	3p21.31	3	49684099	MST1, GPX1, BSN	MST1			ENSG00000173531	NA	NA	rs3197999-A	rs3197999	0	3197999	missense_variant	0	0.297	6e-17	16.2218487496164		1.22	[1.16-1.27]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1q23.3	1	160860478	CD244, ITLN1	CD244			ENSG00000122223	NA	NA	rs4656940-A	rs4656940	0	4656940	intron_variant	0	0.801	6e-07	6.22184874961636		1.15	[1.09-1.21]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	22q13.1	22	39263768	MAP3K7IP1	AL031590.1			ENSG00000284633	NA	NA	rs2413583-C	rs2413583	0	2413583	intron_variant	0	0.83	1e-26	26		1.23	[1.17-1.29]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6p21.33	6	31574531	HLA-DQA2, LTA, TNF, LST1, LTB	LTA - TNF	ENSG00000226275	ENSG00000228321		207	1034	rs1799964-C	rs1799964	0	1799964	regulatory_region_variant	1	0.209	4e-11	10.397940008672		1.19	[1.13-1.25]	Affymetrix, Illumina [953241] (imputed)	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	4q34.3	4	179363660	intergenic	AC018710.1 - AC020551.1	ENSG00000250839	ENSG00000250993		294066	25474	rs6811556-A	rs6811556	0	6811556	intergenic_variant	1	NR	9e-06	5.04575749056067	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	5q21.3	5	108498546	intergenic	AC008462.1 - AC133134.1	ENSG00000286503	ENSG00000244245		80530	95063	rs4571457-G	rs4571457	0	4571457	intergenic_variant	1	NR	7e-06	5.15490195998574	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	6p21.33	6	30831622	IER3, GTF2H4, FLOT1, VARS2, MIR588, DDR1	LINC00243 - LINC02570	ENSG00000214894	ENSG00000225888		963	7904	rs9501030-A	rs9501030	0	9501030	intergenic_variant	1	NR	4e-06	5.39794000867204	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	7p21.1	7	18760790	HDAC9	HDAC9			ENSG00000048052	NA	NA	rs11764116-A	rs11764116	0	11764116	intron_variant	0	NR	2e-06	5.69897000433602	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	7q21.11	7	82228577	CACNA2D1	CACNA2D1			ENSG00000153956	NA	NA	rs929351-C	rs929351	0	929351	intron_variant	0	NR	8e-06	5.09691001300806	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	13q31.1	13	78976799	intergenic	CCT5P2 - NIPA2P5	ENSG00000230584	ENSG00000236277		66257	113984	rs7319358-A	rs7319358	0	7319358	regulatory_region_variant	1	NR	3e-06	5.52287874528034	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	20q11.21	20	33130847	C20orf71, C20orf70	BPIFB4 - BPIFA2	ENSG00000186191	ENSG00000131050		19096	30921	rs6059101-A	rs6059101	0	6059101	regulatory_region_variant	1	NR	4e-06	5.39794000867204	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	14q12	14	28663671	intergenic	LINC02300 - BTF3P2	ENSG00000258175	ENSG00000258282		50048	9570	rs1956388-A	rs1956388	0	1956388	intergenic_variant	1	NR	2e-06	5.69897000433602	(Analysis II)	NA		Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	6p21.32	6	32111790	MHC	TNXB, TNXB, TNXB, TNXB, TNXB, TNXB, AL662884.2, AL662884.5			ENSG00000168477, ENSG00000206258, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000236221, ENSG00000284829, ENSG00000286974	NA	NA	rs17207986-G	rs17207986	0	17207986	non_coding_transcript_exon_variant	0	NR	1e-16	16	(Analysis III)	3.95	[NR]	Illumina [313720]	N
2013-08-20	20848476	Haritunians T	2010-11-01	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/20848476	Genetic predictors of medically refractory ulcerative colitis.	Ulcerative colitis	324 European ancestry medically refractory ulcerative colitis cases, 537 European ancestry non-medically refractory ulcerative colitis cases, 2,601 European ancestry controls	NA	9q32	9	114842790	TNFSF15	TNFSF15 - AL133412.1	ENSG00000181634	ENSG00000229817		36751	2804	rs11554257-G	rs11554257	0	11554257	intergenic_variant	1	NR	1e-06	6	(Analysis III)	1.82	[NR]	Illumina [313720]	N
2013-11-15	23708190	Hu Z	2013-05-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23708190	A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations.	Congenital heart malformation	945 Han Chinese ancestry cases, 1,246 Han Chinese ancestry controls	2,160 Han Chinese ancestry cases, 3,866 Han Chinese ancestry controls	1p12	1	118360355	TBX15, SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126		95866	253978	rs2474937-C	rs2474937	0	2474937	intergenic_variant	1	0.08	8e-10	9.09691001300806		1.4	[1.26-1.56]	Illumina [708275]	N
2013-11-15	23708190	Hu Z	2013-05-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23708190	A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations.	Congenital heart malformation	945 Han Chinese ancestry cases, 1,246 Han Chinese ancestry controls	2,160 Han Chinese ancestry cases, 3,866 Han Chinese ancestry controls	4q31.1	4	139874173	MAML3	MAML3			ENSG00000196782	NA	NA	rs1531070-A	rs1531070	0	1531070	intron_variant	0	0.11	5e-12	11.301029995664		1.4	[1.27-1.54]	Illumina [708275]	N
2011-01-03	21037115	Wan ES	2010-10-29	Am J Respir Cell Mol Biol	www.ncbi.nlm.nih.gov/pubmed/21037115	Genome-wide association analysis of body mass in chronic obstructive pulmonary disease.	Body mass in chronic obstructive pulmonary disease	2,950 European ancestry cases	502 European ancestry cases	16q12.2	16	53782363	FTO	FTO			ENSG00000140718	NA	NA	rs8050136-A	rs8050136	0	8050136	intron_variant	0	0.39	4e-08	7.39794000867204	(BMI)	NA		Illumina [~ 550000]	N
2011-07-07	21665994	Kutalik Z	2011-06-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21665994	Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.	Alcohol consumption (transferrin glycosylation)	5,181 European ancestry individuals	2,284 European ancestry individauls	3q22.1	3	133775510	TF	TF			ENSG00000091513	NA	NA	rs1049296-T	rs1049296	0	1049296	missense_variant	0	0.17	5e-43	42.301029995664	(CDT percent)	0.29	[0.25-0.33] unit decrease	Affymetrix [390631] (imputed)	N
2011-07-07	21665994	Kutalik Z	2011-06-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21665994	Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.	Alcohol consumption (transferrin glycosylation)	5,181 European ancestry individuals	2,284 European ancestry individauls	3q22.1	3	133756968	TF	TF			ENSG00000091513	NA	NA	rs1799899-A	rs1799899	0	1799899	missense_variant	0	0.06	1e-09	9	(CDT concentration)	0.402	[0.27-0.53] unit decrease	Affymetrix [390631] (imputed)	N
2011-07-07	21665994	Kutalik Z	2011-06-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21665994	Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.	Alcohol consumption (transferrin glycosylation)	5,181 European ancestry individuals	2,284 European ancestry individauls	3q22.1	3	133818223	SRPRB	SRPRB			ENSG00000144867	NA	NA	rs1534166-A	rs1534166	0	1534166	intron_variant	0	0.30	2e-17	16.698970004336	(CDT concentration)	0.289	[0.22-0.36] unit decrease	Affymetrix [390631] (imputed)	N
2011-07-07	21665994	Kutalik Z	2011-06-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21665994	Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.	Alcohol consumption (transferrin glycosylation)	5,181 European ancestry individuals	2,284 European ancestry individauls	3q22.1	3	133765185	TF	TF			ENSG00000091513	NA	NA	rs3811647-A	rs3811647	0	3811647	intron_variant	0	0.32	1e-35	35	(Total transferrin)	0.358	[0.30-0.42] unit increase	Affymetrix [390631] (imputed)	N
2011-07-07	21665994	Kutalik Z	2011-06-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21665994	Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.	Alcohol consumption (transferrin glycosylation)	5,181 European ancestry individuals	2,284 European ancestry individauls	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	0.045	2e-32	31.698970004336	(Total transferrin)	0.629	[0.53-0.73] unit decrease	Affymetrix [390631] (imputed)	N
2011-07-07	21665994	Kutalik Z	2011-06-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21665994	Genome-wide association study identifies two loci strongly affecting transferrin glycosylation.	Alcohol consumption (transferrin glycosylation)	5,181 European ancestry individuals	2,284 European ancestry individauls	1p31.3	1	63661797	PGM1	PGM1 - ROR1	ENSG00000079739	ENSG00000185483		1552	112220	rs2749097-G	rs2749097	0	2749097	regulatory_region_variant	1	0.19	2e-09	8.69897000433602	(CDT percent)	0.12	[0.08-0.16] unit decrease	Affymetrix [390631] (imputed)	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	6p12.3	6	51020055	intergenic	FTH1P5 - AL158050.2	ENSG00000230204	ENSG00000270306		106799	365227	rs190759-?	rs190759	0	190759	intergenic_variant	1	0.18	5e-06	5.30102999566398	(Additive)	1.11	[1.06-1.16]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	12q24.32	12	127308069	intergenic	LINC02376 - AC073913.1	ENSG00000256292	ENSG00000256496		23741	9640	rs1823172-?	rs1823172	0	1823172	intergenic_variant	1	0.08	5e-07	6.30102999566398	(Additive)	1.17	[1.10-1.25]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	15q25.1	15	78633676	CHRNB4	CHRNB4			ENSG00000117971	NA	NA	rs950776-?	rs950776	0	950776	intron_variant	0	0.68	4e-07	6.39794000867204	(Additive)	1.09	[1.06-1.13]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	17q23.2	17	62701571	intergenic	AC005821.1, MARCH10			ENSG00000265702, ENSG00000173838	NA	NA	rs2251393-?	rs2251393	0	2251393	3_prime_UTR_variant	0	0.15	4e-07	6.39794000867204	(Additive)	1.13	[1.08-1.18]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	20q13.33	20	61668355	CDH4	CDH4			ENSG00000179242	NA	NA	rs944260-?	rs944260	0	944260	intron_variant	0	0.24	2e-06	5.69897000433602	(Additive)	1.1	[1.06-1.14]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	12q22	12	92496744	PLEKHG7	LINC02397 - AC063949.1	ENSG00000205056	ENSG00000258262		4653	33716	rs10219495-?	rs10219495	0	10219495	intergenic_variant	1	0.10	5e-06	5.30102999566398	(Additive)	1.14	[1.08-1.21]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	12q21.33	12	91586597	DCN	AC090016.1 - AC126175.1	ENSG00000286049	ENSG00000274647		159661	46315	rs10777317-?	rs10777317	0	10777317	intergenic_variant	1	0.60	5e-06	5.30102999566398	(Dominant)	1.12	[1.07-1.18]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	14q32.2	14	100159565	DEGS2	DEGS2			ENSG00000168350	NA	NA	rs7157599-?	rs7157599	0	7157599	missense_variant	0	0.31	1e-07	7	(Dominant)	1.13	[1.08-1.19]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	8q11.21	8	48899642	EFCAB1	AC100805.1 - AC013701.1	ENSG00000286878	ENSG00000233109		75580	14274	rs12155623-?	rs12155623	0	12155623	regulatory_region_variant	1	0.57	3e-07	6.52287874528034	(Dominant)	1.14	[1.09-1.20]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	3q23	3	140456518	CLSTN2	AC010181.1, CLSTN2			ENSG00000249290, ENSG00000158258	NA	NA	rs11708189-?	rs11708189	0	11708189	intron_variant	0	0.65	2e-06	5.69897000433602	(Dominant)	1.12	[1.07-1.18]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	12q23.1	12	97295990	intergenic	LINC02409 - RMST	ENSG00000257920	ENSG00000255794		19781	134894	rs10777845-?	rs10777845	0	10777845	intergenic_variant	1	0.66	5e-06	5.30102999566398	(Dominant)	1.12	[1.07-1.17]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2q24.1	2	157923692	intergenic	UPP2			ENSG00000007001	NA	NA	rs10183640-?	rs10183640	0	10183640	intron_variant	0	0.35	5e-07	6.30102999566398	(Dominant)	1.12	[1.08-1.18]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	1q24.3	1	171292054	FMO1	FMO1 - FMO4	ENSG00000010932	ENSG00000076258		6076	22129	rs6660565-?	rs6660565	0	6660565	intergenic_variant	1	0.72	2e-06	5.69897000433602	(Dominant)	1.12	[1.07-1.18]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	22q13.1	22	39291479	intergenic	AL031590.1 - AL022326.1	ENSG00000284633	ENSG00000224794		11582	1509	rs54211-?	rs54211	0	54211	regulatory_region_variant	1	0.13	8e-07	6.09691001300806	(Recessive)	1.57	[1.32-1.88]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	8q22.3	8	104945312	ZFPM2	ZFPM2			ENSG00000169946	NA	NA	rs16872085-?	rs16872085	0	16872085	intron_variant	0	0.09	1e-06	6	(Recessive)	1.83	[1.44-2.33]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	3p26.3	3	270666	CHL1	CHL1			ENSG00000134121	NA	NA	rs6764363-?	rs6764363	0	6764363	intron_variant	0	0.36	6e-06	5.22184874961636	(Recessive)	1.19	[1.10-1.28]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	12q21.2	12	75826838	intergenic	AC078923.1			ENSG00000258077	NA	NA	rs7307780-?	rs7307780	0	7307780	intron_variant	0	0.19	5e-15	14.301029995664	(Recessive)	1.45	[1.33-1.59]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	11q21	11	96133536	intergenic	AP000779.1, MAML2			ENSG00000285921, ENSG00000184384	NA	NA	rs10765792-?	rs10765792	0	10765792	intron_variant	0	0.11	8e-13	12.0969100130081	(Recessive)	1.54	[1.37-1.72]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	18p11.31	18	6939948	intergenic	RNU6-916P - LAMA1	ENSG00000251897	ENSG00000101680		2928	1794	rs597503-?	rs597503	0	597503	intergenic_variant	1	0.13	2e-08	7.69897000433602	(Recessive)	1.45	[1.27-1.65]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	15q26.2	15	94622351	MCTP2	AC009432.1 - AC022308.1	ENSG00000259331	ENSG00000286917		21530	102577	rs1014922-?	rs1014922	0	1014922	intergenic_variant	1	0.10	3e-06	5.52287874528034	(Recessive)	1.36	[1.20-1.55]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	17q24.3	17	70648048	intergenic	AC005771.1 - AC007423.1	ENSG00000267471	ENSG00000271239		18783	130556	rs17718586-?	rs17718586	0	17718586	intergenic_variant	1	0.10	2e-08	7.69897000433602	(Recessive)	1.53	[1.32-1.78]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	6q25.1	6	151964552	ESR1	ESR1			ENSG00000091831	NA	NA	rs2982694-?	rs2982694	0	2982694	intron_variant	0	0.14	7e-10	9.15490195998574	(Recessive)	1.43	[1.28-1.60]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	17p13.3	17	2868218	GARNL4	RAP1GAP2			ENSG00000132359	NA	NA	rs12603284-?	rs12603284	0	12603284	intron_variant	0	0.08	3e-06	5.52287874528034	(Recessive)	1.89	[1.45-2.47]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	16p13.2	16	9650238	intergenic	AC007221.1 - AC007218.1	ENSG00000283003	ENSG00000260362		35339	16647	rs17550532-?	rs17550532	0	17550532	intergenic_variant	1	0.21	2e-06	5.69897000433602	(Recessive)	1.33	[1.18-1.49]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	15q24.2	15	75426328	SIN3A	SIN3A			ENSG00000169375	NA	NA	rs8028182-?	rs8028182	0	8028182	intron_variant	0	0.18	3e-06	5.52287874528034	(Recessive)	1.36	[1.19-1.54]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	14q11.2	14	23563861	AP1G2	AL135999.1, AP1G2			ENSG00000258727, ENSG00000213983	NA	NA	rs2281680-?	rs2281680	0	2281680	splice_region_variant	0	0.21	6e-08	7.22184874961636	(Recessive)	1.38	[1.23-1.54]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	13q12.12	13	24508492	PARP4	TPTE2P6, PARP4			ENSG00000205822, ENSG00000102699	NA	NA	rs9581094-?	rs9581094	0	9581094	intron_variant	0	0.15	7e-07	6.15490195998574	(Recessive)	1.7	[1.38-2.10]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	12q13.12	12	50819650	ATF1	ATF1			ENSG00000123268	NA	NA	rs17291650-?	rs17291650	0	17291650	synonymous_variant	0	0.10	3e-07	6.52287874528034	(Recessive)	1.43	[1.25-1.64]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	11p14.3	11	23023046	intergenic	AC006299.1 - LINC02718	ENSG00000246225	ENSG00000255418		77653	131637	rs10833905-?	rs10833905	0	10833905	regulatory_region_variant	1	0.22	7e-07	6.15490195998574	(Recessive)	1.32	[1.18-1.47]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	10q23.33	10	94276223	PLCE1	PLCE1			ENSG00000138193	NA	NA	rs11187837-?	rs11187837	0	11187837	intron_variant	0	0.12	4e-07	6.39794000867204	(Recessive)	1.79	[1.43-2.24]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	13q22.1	13	74168185	intergenic	KLF12 - LINC00402	ENSG00000118922	ENSG00000235532		173129	63272	rs12429889-?	rs12429889	0	12429889	intergenic_variant	1	0.16	5e-20	19.301029995664	(Recessive)	1.64	[1.48-1.81]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	5q33.2	5	153677988	GRIA1	GRIA1			ENSG00000155511	NA	NA	rs12189362-?	rs12189362	0	12189362	intron_variant	0	0.12	3e-10	9.52287874528034	(Recessive)	1.5	[1.32-1.69]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	10p12.31	10	18661626	intergenic	ARL5B			ENSG00000165997	NA	NA	rs10829156-?	rs10829156	0	10829156	intron_variant	0	0.20	4e-07	6.39794000867204	(Recessive)	1.28	[1.16-1.41]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	14q31.3	14	87039904	intergenic	AL358292.1 - AL352955.1	ENSG00000259061	ENSG00000258496		50779	211199	rs11624056-?	rs11624056	0	11624056	intergenic_variant	1	0.11	3e-08	7.52287874528034	(Recessive)	1.43	[1.26-1.62]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	22q12.1	22	27694209	intergenic	AL121885.2			ENSG00000227838	NA	NA	rs5762311-?	rs5762311	0	5762311	intron_variant	0	0.09	7e-06	5.15490195998574	(Recessive)	2.03	[1.49-2.75]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	8q21.13	8	77768114	PXMP3	AC062004.1 - AC084706.1	ENSG00000254366	ENSG00000254001		230824	379987	rs3864663-?	rs3864663	0	3864663	intergenic_variant	1	0.15	2e-06	5.69897000433602	(Recessive)	1.4	[1.22-1.61]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	7q21.3	7	97991379	OCM2	OCM2 - RN7SL478P	ENSG00000135175	ENSG00000277946		210	6946	rs13438327-?	rs13438327	0	13438327	intergenic_variant	1	0.09	2e-06	5.69897000433602	(Recessive)	2.05	[1.53-2.76]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	7p21.3	7	12892424	intergenic	AC011287.1			ENSG00000229618	NA	NA	rs732577-?	rs732577	0	732577	intron_variant	0	0.50	4e-06	5.39794000867204	(Recessive)	1.15	[1.08-1.22]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2q32.3	2	192090779	TMEFF2	TMEFF2			ENSG00000144339	NA	NA	rs13007495-?	rs13007495	0	13007495	intron_variant	0	0.14	4e-06	5.39794000867204	(Recessive)	1.47	[1.25-1.73]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2q24.2	2	159213245	intergenic	TANC1			ENSG00000115183	NA	NA	rs13022357-?	rs13022357	0	13022357	intron_variant	0	0.09	1e-06	6	(Recessive)	1.72	[1.38-2.14]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2q24.1	2	154370165	intergenic	GALNT13			ENSG00000144278	NA	NA	rs707040-?	rs707040	0	707040	intron_variant	0	0.38	6e-06	5.22184874961636	(Recessive)	1.17	[1.10-1.26]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	19q13.32	19	45804148	RSHL1	RSPH6A			ENSG00000104941	NA	NA	rs8111071-?	rs8111071	0	8111071	intron_variant	0	0.09	4e-06	5.39794000867204	(Recessive)	2.01	[1.50-2.70]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2p25.1	2	11370822	E2F6	AC099344.1 - AC099344.2	ENSG00000230952	ENSG00000231403		5186	17201	rs6716724-?	rs6716724	0	6716724	intergenic_variant	1	0.18	6e-07	6.22184874961636	(Recessive)	1.39	[1.22-1.57]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2p16.2	2	54120613	ACYP2	ACYP2			ENSG00000170634	NA	NA	rs1559040-?	rs1559040	0	1559040	intron_variant	0	0.11	4e-08	7.39794000867204	(Recessive)	1.54	[1.32-1.79]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	2q31.3	2	179701951	ZNF385B	ZNF385B			ENSG00000144331	NA	NA	rs16866933-?	rs16866933	0	16866933	intron_variant	0	0.09	6e-14	13.2218487496164	(Recessive)	1.69	[1.48-1.93]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	4q26	4	116333133	intergenic	MTRNR2L13 - TRMT112P1	ENSG00000270394	ENSG00000250272		32813	45786	rs2389202-?	rs2389202	0	2389202	intergenic_variant	1	0.13	4e-07	6.39794000867204	(Recessive)	1.43	[1.25-1.65]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	5q22.2	5	113694467	intergenic	YTHDC2 - AC093240.1	ENSG00000047188	ENSG00000286839		99182	43639	rs4621553-?	rs4621553	0	4621553	intergenic_variant	1	0.22	4e-08	7.39794000867204	(Recessive)	1.4	[1.24-1.58]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	18q11.2	18	26576461	KCTD1	KCTD1			ENSG00000134504	NA	NA	rs16942421-?	rs16942421	0	16942421	intron_variant	0	0.08	8e-10	9.09691001300806	(Recessive)	1.68	[1.43-1.98]	Affymetrix [319222]	N
2011-07-20	21658281	Aouizerat BE	2011-06-10	BMC Cardiovasc Disord	www.ncbi.nlm.nih.gov/pubmed/21658281	GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.	Sudden cardiac arrest	88 European ancestry cases, 517 European ancestry controls	NA	7p12.3	7	46202985	intergenic	ZNF619P1 - AC023669.1	ENSG00000224547	ENSG00000229459		57297	58079	rs6964415-?	rs6964415	0	6964415	intergenic_variant	1	0.08	5e-07	6.30102999566398	(Recessive)	1.42	[1.24-1.63]	Affymetrix [319222]	N
2009-01-21	19118814	Beecham GW	2009-01-03	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19118814	Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.	Alzheimer's disease	492 European ancestry cases, 496 European ancestry controls	238 European ancestry cases, 220 European ancestry controls	19q13.31	19	44110055	ZNF224	AC021092.1			ENSG00000186019	NA	NA	rs2061333-?	rs2061333	0	2061333	intron_variant	0	NR	2e-06	5.69897000433602		NA		Illumina [~ 2500000] (imputed)	N
2009-01-21	19118814	Beecham GW	2009-01-03	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19118814	Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.	Alzheimer's disease	492 European ancestry cases, 496 European ancestry controls	238 European ancestry cases, 220 European ancestry controls	12q13.11	12	47245743	FAM113B	AC008083.2			ENSG00000257925	NA	NA	rs11610206-?	rs11610206	0	11610206	intron_variant	0	NR	3e-07	6.52287874528034		NA		Illumina [~ 2500000] (imputed)	N
2009-01-21	19118814	Beecham GW	2009-01-03	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19118814	Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease.	Alzheimer's disease	492 European ancestry cases, 496 European ancestry controls	238 European ancestry cases, 220 European ancestry controls	1q42.2	1	231708601	DISC1	DISC1, TSNAX-DISC1			ENSG00000162946, ENSG00000270106	NA	NA	rs12044355-?	rs12044355	0	12044355	intron_variant	0	NR	9e-06	5.04575749056067		NA		Illumina [~ 2500000] (imputed)	N
2013-05-14	21618603	Beaty TH	2011-05-26	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/21618603	Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate.	Orofacial clefts (maternal alcohol consumption interaction)	272 European ancestry trios, 259 Asian ancestry trios, 19 African ancestry or other ancestry trios	NA	6p24.1	6	11729849	C6orf105	AL022724.3, ADTRP			ENSG00000287593, ENSG00000111863	NA	NA	rs2294426-?	rs2294426	0	2294426	intron_variant	0	NR	4e-08	7.39794000867204	(Maternal alcohol consumption, 1df)	NA		Illumina [~ 498000]	N
2013-05-14	21618603	Beaty TH	2011-05-26	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/21618603	Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate.	Orofacial clefts (maternal alcohol consumption interaction)	272 European ancestry trios, 259 Asian ancestry trios, 19 African ancestry or other ancestry trios	NA	9q31.1	9	104031445	SMC2	AL590381.1 - SMC2-AS1	ENSG00000285483	ENSG00000270332		30976	48579	rs1536895-C	rs1536895	0	1536895	intergenic_variant	1	0.065	3e-07	6.52287874528034	(Maternal alcohol consumption, 1df)	NA		Illumina [~ 498000]	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	1p13.2	1	113834946	PTPN22	PTPN22, AL137856.1			ENSG00000134242, ENSG00000231128	NA	NA	rs2476601-G	rs2476601	0	2476601	missense_variant	0	0.907	4e-09	8.39794000867204		1.26	[1.17-1.37]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	18p11.21	18	12809341	PTPN2	PTPN2			ENSG00000175354	NA	NA	rs1893217-G	rs1893217	0	1893217	intron_variant	0	0.153	1e-14	14		1.25	[1.18-1.32]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5p13.1	5	40410482	PTGER4	AC108105.1 - AC093277.1	ENSG00000287597	ENSG00000283286		97577	4655	rs11742570-C	rs11742570	0	11742570	intergenic_variant	1	0.606	7e-36	35.1549019599857		1.33	[1.27-1.39]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	11q13.1	11	64329761	ESRRA, PRDX5	AP003774.2 - CCDC88B	ENSG00000236935	ENSG00000168071		257	10443	rs694739-A	rs694739	0	694739	regulatory_region_variant	1	0.626	6e-10	9.22184874961636		1.1	[1.05-1.16]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6q21	6	105987150	PRDM1	RN7SKP211 - PRDM1	ENSG00000200198	ENSG00000057657		82463	6313	rs6568421-G	rs6568421	0	6568421	regulatory_region_variant	1	0.301	4e-08	7.39794000867204		1.13	[1.07-1.18]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	16q12.1	16	50722970	NOD2	NOD2			ENSG00000167207	NA	NA	rs2076756-G	rs2076756	0	2076756	intron_variant	0	0.26	4e-69	68.397940008672		1.53	[1.46-1.60]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	10q24.2	10	99524480	NKX2-3	AL391684.1 - LINC01475	ENSG00000224934	ENSG00000257582		61221	1870	rs4409764-T	rs4409764	0	4409764	intergenic_variant	1	0.492	2e-20	19.698970004336		1.22	[1.17-1.27]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2q33.1	2	198032171	PLCL1	PLCL1			ENSG00000115896	NA	NA	rs6738825-A	rs6738825	0	6738825	intron_variant	0	0.473	4e-09	8.39794000867204		1.06	[1.02-1.11]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q31.3	5	142099500	NDFIP1	AC005740.2 - NDFIP1	ENSG00000250347	ENSG00000131507		62375	9279	rs11167764-C	rs11167764	0	11167764	regulatory_region_variant	1	0.796	2e-09	8.69897000433602		1.06	[1.02-1.11]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6p22.3	6	20728500	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs6908425-C	rs6908425	0	6908425	intron_variant	0	0.784	1e-08	8		1.17	[1.11-1.23]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	17q12	17	34266646	CCL2, CCL7	CCL2 - CCL7	ENSG00000108691	ENSG00000108688		9443	3575	rs3091315-A	rs3091315	0	3091315	regulatory_region_variant	1	0.723	2e-13	12.698970004336		1.2	[1.14-1.26]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	2q37.1	2	233275771	ATG16L1	ATG16L1, ATG16L1, SCARNA5, SCARNA5			ENSG00000085978, ENSG00000281089, ENSG00000280652, ENSG00000252010	NA	NA	rs3792109-A	rs3792109	0	3792109	non_coding_transcript_exon_variant	0	0.529	7e-41	40.1549019599857		1.34	[1.29-1.40]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	8q24.21	8	128554935	intergenic	LINC00824			ENSG00000254275	NA	NA	rs6651252-T	rs6651252	0	6651252	intron_variant	0	0.865	4e-18	17.397940008672		1.23	[1.17-1.30]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	8q24.13	8	125525328	intergenic	AC091114.1			ENSG00000253111	NA	NA	rs4871611-A	rs4871611	0	4871611	intron_variant	0	0.609	2e-12	11.698970004336		1.17	[1.12-1.23]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	11q13.5	11	76590331	C11orf30	EMSY - AP001189.2	ENSG00000158636	ENSG00000254755		37306	692	rs7927997-T	rs7927997	0	7927997	intergenic_variant	1	0.389	6e-13	12.2218487496164		1.17	[1.12-1.22]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6q15	6	90263440	BACH2	BACH2			ENSG00000112182	NA	NA	rs1847472-G	rs1847472	0	1847472	intron_variant	0	0.658	5e-09	8.30102999566398		1.07	[1.03-1.11]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	3p24.3	3	18665366	intergenic	SATB1-AS1			ENSG00000228956	NA	NA	rs13073817-A	rs13073817	0	13073817	intron_variant	0	0.322	7e-09	8.15490195998574		1.08	[1.03-1.13]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	5q13.2	5	73255307	intergenic	AC116345.1			ENSG00000249743	NA	NA	rs7702331-A	rs7702331	0	7702331	intron_variant	0	0.6	6e-12	11.2218487496164		1.12	[1.07-1.17]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	6p25.2	6	3433084	intergenic	SLC22A23			ENSG00000137266	NA	NA	rs17309827-T	rs17309827	0	17309827	intron_variant	0	0.639	7e-09	8.15490195998574		1.1	[1.05-1.16]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	19q13.11	19	33266156	intergenic	SLC7A10 - AC008738.6	ENSG00000130876	ENSG00000270212		40306	17822	rs736289-T	rs736289	0	736289	intergenic_variant	1	0.612	9e-09	8.04575749056067		1.06	[1.02-1.11]	Affymetrix, Illumina [953241] (imputed)	N
2012-10-19	21102463	Franke A	2010-11-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21102463	Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.	Crohn's disease	6,333 European ancestry cases, 15,056 European ancestry controls	15,694 European ancestry cases, 14,026 European ancestry controls, 414 European ancestry trios	21q21.1	21	15440233	intergenic	AJ009632.2			ENSG00000229425	NA	NA	rs1736020-C	rs1736020	0	1736020	intron_variant	0	0.579	9e-12	11.0457574905607		1.16	[1.11-1.21]	Affymetrix, Illumina [953241] (imputed)	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	3q23	3	141383991	ZBTB38	ZBTB38			ENSG00000177311	NA	NA	rs6763931-A	rs6763931	0	6763931	intron_variant	0	0.45	1e-27	27		7.4	[6.03-8.77] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	Xq21.1	X	79393696	ITM2A	AL009028.1 - TBX22	ENSG00000270268	ENSG00000122145		23531	621057	rs1474563-T	rs1474563	0	1474563	intergenic_variant	1	0.58	3e-06	5.52287874528034		3.5	[1.93-5.07] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	17q22	17	56772968	COIL, RISK, NOG, DGKE, TRIM25	NOG - C17orf67	ENSG00000183691	ENSG00000214226		177370	18945	rs4794665-A	rs4794665	0	4794665	intergenic_variant	1	0.48	1e-07	7		3.6	[2.23-4.97] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6q23.1	6	130037283	L3MBTL3, SAMD3	L3MBTL3			ENSG00000198945	NA	NA	rs6899976-G	rs6899976	0	6899976	intron_variant	0	0.28	6e-06	5.22184874961636		3.8	[2.23-5.37] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	2q37.1	2	231931900	DIS3L2, NPPC, COPS7B, PDE6D, PTMA	NPPC - DIS3L2	ENSG00000163273	ENSG00000144535		5504	29345	rs749052-A	rs749052	0	749052	intergenic_variant	1	0.94	1e-06	6		8.7	[5.17-12.23] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	17q11.2	17	30920697	CRLF3, ATAD5, CENTA2, RNF135	ADAP2			ENSG00000184060	NA	NA	rs3760318-C	rs3760318	0	3760318	intron_variant	0	0.63	2e-09	8.69897000433602		6	[4.04-7.96] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	22q11.23	22	23250864	BCR, GNAZ, RTDR1, IGLL1	BCR			ENSG00000186716	NA	NA	rs5751614-A	rs5751614	0	5751614	intron_variant	0	0.49	6e-06	5.22184874961636		4.3	[2.34-6.26] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	18q11.2	18	23144364	RBBP8, CABLES1, C18orf45	CABLES1			ENSG00000134508	NA	NA	rs4800148-A	rs4800148	0	4800148	intron_variant	0	0.79	4e-09	8.39794000867204		6.4	[4.24-8.56] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	1q25.3	1	184051811	GLT25D2, C1orf19	TSEN15			ENSG00000198860	NA	NA	rs2274432-T	rs2274432	0	2274432	missense_variant	0	0.37	8e-09	8.09691001300806		5.3	[3.54-7.06] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	19p13.2	19	8607115	MYO1F, PRAM1, OR2Z1, ADAMTS10	ADAMTS10			ENSG00000142303	NA	NA	rs7249094-G	rs7249094	0	7249094	intron_variant	0	0.59	1e-06	6		4.3	[2.54-6.06] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	17q23.3	17	63635604	MAP3K3, WDR68, LYK5, MT1F	MAP3K3			ENSG00000198909	NA	NA	rs7209435-C	rs7209435	0	7209435	intron_variant	0	0.27	7e-07	6.15490195998574		4.8	[2.84-6.76] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	15q25.2	15	83647132	SH3GL3, ADAMTSL3	SH3GL3 - ADAMTSL3	ENSG00000140600	ENSG00000156218		28389	6956	rs2554380-T	rs2554380	0	2554380	intergenic_variant	1	0.78	9e-07	6.04575749056067		4.5	[2.74-6.26] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	12p12.2	12	20605679	SLCO1B3, PDE3A, SLCO1C1	PDE3A			ENSG00000172572	NA	NA	rs11611208-A	rs11611208	0	11611208	intron_variant	0	0.06	2e-06	5.69897000433602		11.4	[6.7-16.1] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	9q31.2	9	106870072	ZNF462	ZNF462			ENSG00000148143	NA	NA	rs4743034-A	rs4743034	0	4743034	intron_variant	0	0.23	2e-08	7.69897000433602		5.3	[3.54-7.06] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	9q32	9	114287611	COL27A1	COL27A1			ENSG00000196739	NA	NA	rs946053-T	rs946053	0	946053	intron_variant	0	0.52	2e-07	6.69897000433602		4.4	[2.83-5.97] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6q16.3	6	104970103	BVES, LIN28B, POPDC3, HACE1	LIN28B			ENSG00000187772	NA	NA	rs314268-C	rs314268	0	314268	intron_variant	0	0.34	8e-07	6.09691001300806		4.6	[2.84-6.36] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p22.3	6	17699091	NUP153, CAP2, KIF13A	NUP153			ENSG00000124789	NA	NA	rs12199222-T	rs12199222	0	12199222	intron_variant	0	0.33	7e-07	6.15490195998574		4.4	[2.64-6.16] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	2p23.3	2	25053415	DTNB, ADCY3, RBJ, POMC, DNMT3A	EFR3B			ENSG00000084710	NA	NA	rs6733301-G	rs6733301	0	6733301	intron_variant	0	0.87	8e-07	6.09691001300806		7.5	[4.56-10.44] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	20p12.3	20	6640246	BMP2	CASC20 - LINC01713	ENSG00000229876	ENSG00000228482		111787	90834	rs967417-C	rs967417	0	967417	intergenic_variant	1	0.53	2e-08	7.69897000433602		4.3	[2.73-5.87] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	3q26.2	3	168119960	GOLIM4, SERPINI1	GOLIM4 - EGFEM1P	ENSG00000173905	ENSG00000206120		24036	129562	rs4345115-T	rs4345115	0	4345115	intergenic_variant	1	0.63	7e-06	5.15490195998574		4.4	[2.44-6.36] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	8q12.1	8	56183249	CHCHD7, RDHE2, MOS, RPS20, LYN, PLAG1, TGS1, PENK	PLAG1			ENSG00000181690	NA	NA	rs10958476-C	rs10958476	0	10958476	intron_variant	0	0.23	7e-08	7.15490195998574		5.4	[3.44-7.36] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	12q22	12	93583178	MRPL42, CRADD, UBE2N, SOCS2	SOCS2			ENSG00000120833	NA	NA	rs3825199-C	rs3825199	0	3825199	3_prime_UTR_variant	0	0.24	2e-07	6.69897000433602		6.2	[3.85-8.55] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	13q14.3	13	50532419	DLEU7	DLEU7, DLEU1			ENSG00000186047, ENSG00000176124	NA	NA	rs1239947-G	rs1239947	0	1239947	intron_variant	0	0.35	8e-06	5.09691001300806		3.8	[2.23-5.37] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	16q24.1	16	84954073	ZDHHC7, CRISPLD2, USP10	LINC02176 - ZDHHC7	ENSG00000260340	ENSG00000153786		14470	20108	rs2326458-C	rs2326458	0	2326458	intergenic_variant	1	0.26	8e-07	6.09691001300806		5.1	[3.14-7.06] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p22.2	6	26233159	Histone class 1, Butyrophilin genes	HIST1H2APS3			ENSG00000218281	NA	NA	rs10946808-A	rs10946808	0	10946808	non_coding_transcript_exon_variant	0	0.7	6e-10	9.22184874961636		5.6	[3.84-7.36] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	12q15	12	69434901	FRS2, LYZ, YEATS4, CPSF6, CCT2, LRRC10	RPS26P45 - LINC02373	ENSG00000241765	ENSG00000257507		11906	14569	rs11177669-A	rs11177669	0	11177669	intergenic_variant	1	0.31	3e-06	5.52287874528034		4.5	[2.54-6.46] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6q21	6	109420812	PPIL6, SMPD2, MNICAL1, ZBTB24, CD164	PPIL6			ENSG00000185250	NA	NA	rs9487094-G	rs9487094	0	9487094	intron_variant	0	0.69	4e-06	5.39794000867204		4.7	[2.74-6.66] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	9q22.1	9	88196267	CCRK, SPIN1	AL451142.2 - RPSAP49	ENSG00000229288	ENSG00000226327		6065	128187	rs2814828-T	rs2814828	0	2814828	intergenic_variant	1	0.25	9e-07	6.04575749056067		5.4	[3.24-7.56] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	7p22.3	7	2723468	GNA12	AMZ1			ENSG00000174945	NA	NA	rs798544-G	rs798544	0	798544	intron_variant	0	0.72	7e-15	14.1549019599857		5.9	[6.03-8.77] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	20q11.22	20	35321981	UQCC, CEP250, GDF5, MMP24, EIF6	UQCC1			ENSG00000101019	NA	NA	rs6088792-T	rs6088792	0	6088792	intron_variant	0	0.26	8e-07	6.09691001300806		4.7	[2.74-6.66] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	4q31.21	4	144653692	HHIP	AC098588.3, HHIP, HHIP-AS1, AC098588.2			ENSG00000285783, ENSG00000164161, ENSG00000248890, ENSG00000285713	NA	NA	rs1812175-C	rs1812175	0	1812175	intron_variant	0	0.86	1e-11	11		8.3	[5.95-10.65] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	14q32.12	14	91960878	TRIP11, ATXN3, FBLN5, CPSF2	FBLN5 - TRIP11	ENSG00000140092	ENSG00000100815		12891	5113	rs7153027-A	rs7153027	0	7153027	intergenic_variant	1	0.52	1e-10	10		5.7	[3.94-7.46] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	5q31.1	5	135036995	DDX46, CAMLG, CATSPER3, PCBD2, PITX1, TXNDC15	C5orf66			ENSG00000224186	NA	NA	rs31198-T	rs31198	0	31198	intron_variant	0	0.75	8e-06	5.09691001300806		4.8	[2.64-6.96] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6q22.32	6	126514509	C6orf173	AL356534.1			ENSG00000286215	NA	NA	rs1490388-T	rs1490388	0	1490388	intron_variant	0	0.42	6e-07	6.22184874961636		4.8	[2.84-6.76] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	2p16.1	2	55869757	EFEMP1, PNPT1	EFEMP1			ENSG00000115380	NA	NA	rs3791679-T	rs3791679	0	3791679	intron_variant	0	0.81	6e-11	10.2218487496164		5.8	[4.04-7.56] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p21.31	6	34227234	LBH, HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309		7168	9639	rs1776897-C	rs1776897	0	1776897	regulatory_region_variant	1	0.07	1e-08	8		8.8	[5.66-11.94] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	4p15.31	4	18016107	LCORL, NCAPG	LCORL			ENSG00000178177	NA	NA	rs6830062-T	rs6830062	0	6830062	intron_variant	0	0.89	1e-10	10		6.3	[4.34-8.26] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	7q21.2	7	92635096	CDK6, PEX1, GATAD1, ERVWE1	CDK6			ENSG00000105810	NA	NA	rs2282978-C	rs2282978	0	2282978	intron_variant	0	0.29	1e-08	8		5.8	[3.84-7.76] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	8q21.13	8	77247943	ZFHX4, PXMP3	HIGD1AP18 - AC062004.1	ENSG00000253952	ENSG00000254366		233915	151129	rs7846385-C	rs7846385	0	7846385	intergenic_variant	1	0.27	5e-08	7.30102999566398		5	[3.24-6.76] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	12p13.2	12	11702690	ETV6	ETV6			ENSG00000139083	NA	NA	rs2187642-A	rs2187642	0	2187642	intron_variant	0	0.39	2e-06	5.69897000433602		4.6	[2.64-6.56] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	15q26.3	15	100246066	ADAMTS17	ADAMTS17			ENSG00000140470	NA	NA	rs4533267-A	rs4533267	0	4533267	intron_variant	0	0.28	3e-08	7.52287874528034		5.6	[3.64-7.56] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	17q23.2	17	61419916	BCAS3, TBX4, TBX2, NACA2	C17orf82 - TBX4	ENSG00000187013	ENSG00000121075		6636	32488	rs757608-T	rs757608	0	757608	regulatory_region_variant	1	0.35	6e-08	7.22184874961636		4.4	[2.83-5.97] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	4q21.21	4	81228677	BMP3, PRKG2, RASGEF1B	PRKG2 - RNU5A-2P	ENSG00000138669	ENSG00000207065		13560	105626	rs710841-A	rs710841	0	710841	intergenic_variant	1	0.27	2e-06	5.69897000433602		5	[3.04-6.96] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	2q35	2	219069626	IHH, CRYBA2, FEV, SLC23A3, TUBA1	AC097468.3, AC097468.4			ENSG00000272644, ENSG00000286606	NA	NA	rs1052483-C	rs1052483	0	1052483	non_coding_transcript_exon_variant	0	0.91	1e-06	6		6.9	[4.16-9.64] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	12q14.3	12	65965972	HMGA2	HMGA2			ENSG00000149948	NA	NA	rs8756-C	rs8756	0	8756	3_prime_UTR_variant	0	0.52	2e-16	15.698970004336		6.6	[5.03-8.17] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p21.1	6	45127426	SUPT3H, RUNX2	SUPT3H			ENSG00000196284	NA	NA	rs9395066-C	rs9395066	0	9395066	intron_variant	0	0.48	8e-06	5.09691001300806		3.5	[1.93-5.07] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p21.31	6	35435008	ANKS1A, TCP11, ZNF76, DEF6, SCUBE3	PPARD - AL022721.1	ENSG00000112033	ENSG00000227154		6817	8036	rs4713858-G	rs4713858	0	4713858	regulatory_region_variant	1	0.86	4e-08	7.39794000867204		6.8	[4.45-9.15] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p21.33	6	32082290	HLA class III	TNXB, TNXB, TNXB, TNXB, TNXB, TNXB			ENSG00000168477, ENSG00000206258, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000236221	NA	NA	rs185819-T	rs185819	0	185819	missense_variant	0	0.52	3e-08	7.52287874528034		5.2	[3.44-6.96] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	1q24.3	1	172220749	DNM3	DNM3			ENSG00000197959	NA	NA	rs678962-G	rs678962	0	678962	intron_variant	0	0.22	3e-08	7.52287874528034		5.4	[3.44-7.36] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	1q21.2	1	149920979	Histone class 2A, MTMR11, SV2A, SF3B4	SV2A - SF3B4	ENSG00000159164	ENSG00000143368		3135	2338	rs11205277-G	rs11205277	0	11205277	intergenic_variant	1	0.44	1e-10	10		5.1	[3.53-6.67] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2010-12-09	20972440	Houlston RS	2010-10-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20972440	Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.	Colorectal cancer	3,334 European ancestry cases, 4,628 European ancestry controls	14,851 European ancestry cases, 15,569 European ancestry controls	1q41	1	221991606	DUSP10	LINC02474 - LINC01705	ENSG00000228437	ENSG00000232679		6642	19219	rs6687758-G	rs6687758	0	6687758	regulatory_region_variant	1	NR	2e-09	8.69897000433602		1.09	[1.06-1.12]	Illumina [up to 550000] (imputed)	N
2010-12-09	20972440	Houlston RS	2010-10-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20972440	Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.	Colorectal cancer	3,334 European ancestry cases, 4,628 European ancestry controls	14,851 European ancestry cases, 15,569 European ancestry controls	20q13.33	20	62345988	LAMA5	LAMA5			ENSG00000130702	NA	NA	rs4925386-C	rs4925386	0	4925386	intron_variant	0	NR	2e-10	9.69897000433602		1.08	[1.05-1.10]	Illumina [up to 550000] (imputed)	N
2010-12-09	20972440	Houlston RS	2010-10-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20972440	Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.	Colorectal cancer	3,334 European ancestry cases, 4,628 European ancestry controls	14,851 European ancestry cases, 15,569 European ancestry controls	3q26.2	3	169774313	MYNN	MYNN			ENSG00000085274	NA	NA	rs10936599-C	rs10936599	0	10936599	synonymous_variant	0	NR	3e-08	7.52287874528034		1.04	[1.04-1.10]	Illumina [up to 550000] (imputed)	N
2010-12-09	20972440	Houlston RS	2010-10-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20972440	Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.	Colorectal cancer	3,334 European ancestry cases, 4,628 European ancestry controls	14,851 European ancestry cases, 15,569 European ancestry controls	12q13.12	12	50761880	DIP2B, ATF1	AC013244.1 - ATF1	ENSG00000271018	ENSG00000123268		4447	1830	rs11169552-C	rs11169552	0	11169552	intergenic_variant	1	NR	2e-10	9.69897000433602		1.09	[1.05-1.11]	Illumina [up to 550000] (imputed)	N
2010-12-09	20972440	Houlston RS	2010-10-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20972440	Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.	Colorectal cancer	3,334 European ancestry cases, 4,628 European ancestry controls	14,851 European ancestry cases, 15,569 European ancestry controls	1q41	1	221872104	DUSP10	LINC01655 - LINC02257	ENSG00000227925	ENSG00000238042		31387	8877	rs6691170-T	rs6691170	0	6691170	intergenic_variant	1	NR	1e-09	9		1.06	[1.03-1.09]	Illumina [up to 550000] (imputed)	N
2008-06-16	18369459	Liu Y	2008-04-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18369459	A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.	Psoriasis	218 European ancestry cases, 519 European ancestry controls	1,153 European ancestry cases, 1,217 European ancestry controls	13q14.11	13	39776775	COG6	COG6			ENSG00000133103	NA	NA	rs7993214-?	rs7993214	0	7993214	intron_variant	0	0.65	2e-06	5.69897000433602		1.41	[1.22-1.61]	Illumina [305983]	N
2008-06-16	18369459	Liu Y	2008-04-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18369459	A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.	Psoriasis	218 European ancestry cases, 519 European ancestry controls	1,153 European ancestry cases, 1,217 European ancestry controls	6p21.33	6	31464003	HLA-C	HCP5			ENSG00000206337	NA	NA	rs2395029-C	rs2395029	0	2395029	non_coding_transcript_exon_variant	0	0.03	2e-26	25.698970004336		4.1	[3.10-5.30]	Illumina [305983]	N
2008-06-16	18369459	Liu Y	2008-04-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18369459	A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.	Psoriasis	218 European ancestry cases, 519 European ancestry controls	1,153 European ancestry cases, 1,217 European ancestry controls	6p21.33	6	31306778	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs10484554-T	rs10484554	0	10484554	intron_variant	0	0.15	2e-39	38.698970004336		2.8	[2.40-3.30]	Illumina [305983]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6p24.3	6	7719826	BMP6	AL390026.1 - BMP6	ENSG00000236512	ENSG00000153162		98948	6273	rs12198986-A	rs12198986	0	12198986	regulatory_region_variant	1	0.5	2e-11	10.698970004336		6.8	[4.84-8.76] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2008-07-01	18391951	Gudbjartsson DF	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391951	Many sequence variants affecting diversity of adult human height.	Height	30,968 European ancestry individuals	8,541 European ancestry individuals	6q24.2	6	142446496	GPR126	ADGRG6 - AL359313.1	ENSG00000112414	ENSG00000236366		230	79959	rs3748069-A	rs3748069	0	3748069	intergenic_variant	1	0.74	5e-14	13.301029995664		6.5	[5.44-9.36] % s.d. increase	Affymetrix, Illumina [up to 304226]	N
2009-09-28	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Mean forced vital capacity from 2 exams	Up to 1,222 individuals	NA	7q21.3	7	94424688	COL1A2	COL1A2			ENSG00000164692	NA	NA	rs441051-?	rs441051	0	441051	non_coding_transcript_exon_variant	0	NR	2e-06	5.69897000433602	(meanFVC)	NA		Affymetrix [70897]	N
2009-09-28	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Mean forced vital capacity from 2 exams	Up to 1,222 individuals	NA	4q25	4	107194065	intergenic	DKK2			ENSG00000155011	NA	NA	rs10516541-?	rs10516541	0	10516541	intron_variant	0	NR	4e-06	5.39794000867204	(meanFVC)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	14q22.1	14	52052093	NID2	NID2			ENSG00000087303	NA	NA	rs730532-?	rs730532	0	730532	intron_variant	0	NR	6e-06	5.22184874961636	(ppFEF)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	15q11.2	15	24833640	SNRPN	SNRPN, AC090983.2			ENSG00000128739, ENSG00000286110	NA	NA	rs3867498-?	rs3867498	0	3867498	intron_variant	0	NR	1e-06	6	(FEV1slope)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	15q26.1	15	92507736	FLJ32831	C15orf32 - LINC00930	ENSG00000183643	ENSG00000258647		6619	60081	rs1455782-?	rs1455782	0	1455782	intergenic_variant	1	NR	4e-06	5.39794000867204	(ppFVC)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	2q36.3	2	226908750	RHBDD1	RHBDD1			ENSG00000144468	NA	NA	rs3820928-?	rs3820928	0	3820928	intron_variant	0	NR	5e-06	5.30102999566398	(ppFEV1)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	1q21.3	1	154453788	IL6R	IL6R			ENSG00000160712	NA	NA	rs4129267-?	rs4129267	0	4129267	intron_variant	0	NR	7e-06	5.15490195998574	(ppFEF)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	17p12	17	15428200	CDRT4	AC005703.4 - CDRT4	ENSG00000266667	ENSG00000239704		10322	7815	rs2906966-?	rs2906966	0	2906966	intergenic_variant	1	NR	8e-06	5.09691001300806	(ppFEV1)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	7q33	7	138364642	intergenic	AC008155.1 - PTMAP10	ENSG00000213238	ENSG00000213237		66158	39553	rs357394-?	rs357394	0	357394	intergenic_variant	1	NR	9e-06	5.04575749056067	(ppFVC)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	8q11.21	8	50500031	SNTG1	SNTG1			ENSG00000147481	NA	NA	rs310558-?	rs310558	0	310558	intron_variant	0	NR	5e-06	5.30102999566398	(ppratio)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	14q23.1	14	57931198	intergenic	SLC35F4			ENSG00000151812	NA	NA	rs808225-?	rs808225	0	808225	intron_variant	0	NR	7e-06	5.15490195998574	(ppfefrat)	NA		Affymetrix [70897]	N
2008-09-10	17903307	Wilk JB	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903307	Framingham Heart Study genome-wide association: results for pulmonary function measures.	Pulmonary function	Up to 1,222 individuals	NA	21q22.3	21	45209675	ADARB1	ADARB1			ENSG00000197381	NA	NA	rs2838815-?	rs2838815	0	2838815	intron_variant	0	NR	3e-06	5.52287874528034	(meanratio)	NA		Affymetrix [70897]	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	17q22	17	56352794	ANKFN1	ANKFN1			ENSG00000153930	NA	NA	rs12449568-C	rs12449568	0	12449568	intron_variant	0	0.47	2e-06	5.69897000433602		0.25	[0.15-0.35] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	7q21.2	7	92627591	CDK6	CDK6			ENSG00000105810	NA	NA	rs2040494-C	rs2040494	0	2040494	intron_variant	0	0.5	4e-07	6.39794000867204		0.26	[0.36-0.65] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	8q12.1	8	56243039	CHCHD7, RDHE2	AC107952.2 - AC107952.1	ENSG00000272343	ENSG00000254216		19866	9921	rs9650315-T	rs9650315	0	9650315	intergenic_variant	1	0.13	4e-07	6.39794000867204		0.43	[0.59-1.07] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	19p13.3	19	2170955	DOT1L	DOT1L			ENSG00000104885	NA	NA	rs12986413-T	rs12986413	0	12986413	intron_variant	0	0.45	3e-08	7.52287874528034		0.31	[0.21-0.46] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	9q34.11	9	130588697	FUBP3	FUBP3			ENSG00000107164	NA	NA	rs7466269-G	rs7466269	0	7466269	intron_variant	0	0.33	8e-07	6.09691001300806		0.27	[0.38-0.69] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	6q24.2	6	142382740	GPR126	ADGRG6			ENSG00000112414	NA	NA	rs4896582-A	rs4896582	0	4896582	intron_variant	0	0.27	2e-18	17.698970004336		0.38	[0.28-0.48] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	4q31.21	4	144728869	HHIP	AC098588.2, HHIP, AC098588.3			ENSG00000285713, ENSG00000164161, ENSG00000285783	NA	NA	rs1492820-G	rs1492820	0	1492820	intron_variant	0	0.48	1e-11	11		0.29	[0.21-0.37] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	6p22.2	6	26233159	HIST1H1D	HIST1H2APS3			ENSG00000218281	NA	NA	rs10946808-G	rs10946808	0	10946808	non_coding_transcript_exon_variant	0	0.28	4e-17	16.397940008672		0.36	[0.26-0.46] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	12q14.3	12	65964567	HMGA2	HMGA2			ENSG00000149948	NA	NA	rs1042725-T	rs1042725	0	1042725	3_prime_UTR_variant	0	0.49	3e-20	19.5228787452803		0.48	[0.58-1.09] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	6q16.3	6	104959787	LIN28B	LIN28B			ENSG00000187772	NA	NA	rs314277-A	rs314277	0	314277	intron_variant	0	0.13	1e-08	8		0.41	[0.26-0.59] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	14q13.3	14	36530844	NKX2-1	AL132857.1			ENSG00000283098	NA	NA	rs17104630-G	rs17104630	0	17104630	intron_variant	0	0.04	8e-06	5.09691001300806		0.42	[0.61-1.10] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	9q33.1	9	116372517	PAPPA	PAPPA			ENSG00000182752	NA	NA	rs7869550-G	rs7869550	0	7869550	intron_variant	0	0.24	1e-06	6		0.33	[0.45-0.82] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	16p13.3	16	625680	RAB40C	RAB40C			ENSG00000197562	NA	NA	rs763014-C	rs763014	0	763014	non_coding_transcript_exon_variant	0	0.43	5e-06	5.30102999566398		0.24	[0.12-0.29] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	15q25.2	15	83617740	SH3GL3, ADAMTSL3	SH3GL3			ENSG00000140600	NA	NA	rs2562784-G	rs2562784	0	2562784	intron_variant	0	0.17	6e-08	7.22184874961636		0.34	[0.21-0.48] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	14q32.12	14	91993614	TRIP11, ATXN3	TRIP11			ENSG00000100815	NA	NA	rs8007661-T	rs8007661	0	8007661	intron_variant	0	0.3	6e-10	9.22184874961636		0.42	[0.30-0.54] cm decrease	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	20q11.22	20	35319358	UQCC, GDF5	UQCC1			ENSG00000101019	NA	NA	rs6060369-C	rs6060369	0	6060369	intron_variant	0	0.36	1e-16	16		0.44	[0.34-0.72] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	7q36.3	7	158932098	WDR60	WDR60			ENSG00000126870	NA	NA	rs2730245-G	rs2730245	0	2730245	intron_variant	0	0.33	3e-07	6.52287874528034		0.32	[0.19-0.44] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-12	18391950	Lettre G	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391950	Identification of ten loci associated with height highlights new biological pathways in human growth.	Height	15,821 European ancestry individuals	Up to 17,801 European ancestry individuals	3q23	3	141386728	ZBTB38	ZBTB38			ENSG00000177311	NA	NA	rs724016-G	rs724016	0	724016	5_prime_UTR_variant	0	0.48	8e-22	21.0969100130081		0.37	[0.29-0.45] cm increase	Affymetrix, Illumina [2260683] (imputed)	N
2008-09-16	18385739	Thorgeirsson TE	2008-04-03	Nature	www.ncbi.nlm.nih.gov/pubmed/18385739	A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.	Nicotine dependence	10,995 European ancestry individuals	4,848 European ancestry individuals	15q25.1	15	78601997	CHRNA5, CHRNA3, CHRNB4	CHRNA3			ENSG00000080644	NA	NA	rs1051730-T	rs1051730	0	1051730	synonymous_variant	0	0.35	6e-20	19.2218487496164		0.1	[0.08-0.12] cigarettes per day increase	Illumina [306207]	N
2009-02-27	19136949	Carrasquillo MM	2009-01-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19136949	Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease.	Alzheimer's disease	844 European ancestry cases, 1,255 European ancestry controls	1,547 European ancestry cases, 1,209 European ancestry controls	Xq21.31	X	92147221	PCDH11X	PCDH11X			ENSG00000102290	NA	NA	rs2573905-?	rs2573905	0	2573905	intron_variant	0	0.46	2e-07	6.69897000433602		1.29	[1.17-1.42]	Illumina [313504]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-G	rs2736100	0	2736100	3_prime_UTR_variant	0	0.49	2e-17	16.698970004336		1.27	[1.19-1.37]	Illumina [454576]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	8q24.21	8	129673211	CCDC26	CCDC26			ENSG00000229140	NA	NA	rs4295627-G	rs4295627	0	4295627	intron_variant	0	0.83	2e-18	17.698970004336		1.36	[1.29-1.43]	Illumina [454576]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	8q24.21	8	129479506	CCDC26	CCDC26			ENSG00000229140	NA	NA	rs891835-G	rs891835	0	891835	intron_variant	0	0.79	8e-11	10.0969100130081		1.24	[1.17-1.30]	Illumina [454576]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	5p15.33	5	1288432	TERT	TERT			ENSG00000164362	NA	NA	rs2853676-A	rs2853676	0	2853676	intron_variant	0	0.73	4e-14	13.397940008672		1.26	[1.20-1.32]	Illumina [454576]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	11q23.3	11	118606652	PHLDB1	PHLDB1			ENSG00000019144	NA	NA	rs498872-T	rs498872	0	498872	5_prime_UTR_variant	0	0.69	1e-08	8		1.18	[1.13-1.24]	Illumina [454576]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	20q13.33	20	63678486	RTEL1	RTEL1-TNFRSF6B, RTEL1			ENSG00000026036, ENSG00000258366	NA	NA	rs6010620-G	rs6010620	0	6010620	intron_variant	0	0.23	3e-12	11.5228787452803		1.28	[1.21-1.35]	Illumina [454576]	N
2009-07-12	19578367	Shete S	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578367	Genome-wide association study identifies five susceptibility loci for glioma.	Glioma	1,878 European ancestry cases, 3,670 European ancestry controls	2,545 European ancestry cases, 2,953 European ancestry controls	9p21.3	9	22068653	CDKN2A, CDKN2B	CDKN2B-AS1			ENSG00000240498	NA	NA	rs4977756-G	rs4977756	0	4977756	intron_variant	0	0.60	7e-15	14.1549019599857		1.24	[1.19-1.30]	Illumina [454576]	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	4q31.21	4	144564586	HHIP	AC098588.2, AC098588.3			ENSG00000285713, ENSG00000285783	NA	NA	rs1980057-T	rs1980057	0	1980057	intron_variant	0	0.40	3e-20	19.5228787452803	(FEV1/FVC)	0.52	[NR] % increase	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	6q24.2	6	142429379	GPR126	ADGRG6			ENSG00000112414	NA	NA	rs3817928-A	rs3817928	0	3817928	intron_variant	0	0.78	1e-09	9	(FEV1/FVC)	0.42	[NR] % decrease	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	6p21.32	6	32183666	AGER, PPT2	AGER, AGER, AGER, AGER, AGER, AGER, AGER			ENSG00000204305, ENSG00000234729, ENSG00000230514, ENSG00000237405, ENSG00000231268, ENSG00000206320, ENSG00000229058	NA	NA	rs2070600-T	rs2070600	0	2070600	missense_variant	0	0.04	3e-14	13.5228787452803	(FEV1/FVC)	1	[NR] % increase	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	4q22.1	4	88948181	FAM13A	FAM13A			ENSG00000138640	NA	NA	rs2869967-T	rs2869967	0	2869967	intron_variant	0	0.61	1e-07	7	(FEV1/FVC)	0.3	[NR] % increase	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	9q22.32	9	95468726	PTCH1	PTCH1			ENSG00000185920	NA	NA	rs16909898-A	rs16909898	0	16909898	intron_variant	0	0.90	5e-07	6.30102999566398	(FEV1/FVC)	0.5	[NR] % increase	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	4q24	4	105697983	GSTCD, INTS12, NPNT, FLJ20184	INTS12, ARHGEF38			ENSG00000138785, ENSG00000236699	NA	NA	rs11727189-T	rs11727189	0	11727189	intron_variant	0	0.06	5e-17	16.301029995664	(FEV1)	64.7	[NR] ml increase	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	5q32	5	148462790	HTR4	HTR4			ENSG00000164270	NA	NA	rs11168048-T	rs11168048	0	11168048	intron_variant	0	0.58	1e-11	11	(FEV1/FVC)	0.4	[NR] % decrease	Affymetrix, Illumina [2534500] (imputed)	N
2010-01-13	20010835	Hancock DB	2009-12-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20010835	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	Pulmonary function	20,890 European ancestry individuals	16,178 European ancestry individuals	5q33.3	5	157505368	ADAM19	ADAM19			ENSG00000135074	NA	NA	rs2277027-A	rs2277027	0	2277027	intron_variant	0	0.71	1e-10	10	(FEV1/FVC)	0.38	[NR] % increase	Affymetrix, Illumina [2534500] (imputed)	N
2010-03-25	20185149	Athanasiu L	2010-02-23	J Psychiatr Res	www.ncbi.nlm.nih.gov/pubmed/20185149	Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.	Schizophrenia	201 European ancestry cases, 305 European ancestry controls	2,663 European ancestry cases, 13,780 European ancestry controls	16p12.3	16	20668884	ACSM1	ACSM1, ACSM3			ENSG00000166743, ENSG00000005187	NA	NA	rs433598-T	rs433598	0	433598	intron_variant	0	NR	3e-06	5.52287874528034		1.13	[NR]	Affymetrix [572888]	N
2010-03-25	20185149	Athanasiu L	2010-02-23	J Psychiatr Res	www.ncbi.nlm.nih.gov/pubmed/20185149	Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.	Schizophrenia	201 European ancestry cases, 305 European ancestry controls	2,663 European ancestry cases, 13,780 European ancestry controls	9p21.2	9	26935998	PLAA	PLAA			ENSG00000137055	NA	NA	rs7045881-?	rs7045881	0	7045881	intron_variant	0	NR	2e-06	5.69897000433602		1.16	[NR]	Affymetrix [572888]	N
2010-03-25	20185149	Athanasiu L	2010-02-23	J Psychiatr Res	www.ncbi.nlm.nih.gov/pubmed/20185149	Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort.	Schizophrenia	201 European ancestry cases, 305 European ancestry controls	2,663 European ancestry cases, 13,780 European ancestry controls	10q21.2	10	60325579	ANK3	ANK3			ENSG00000151150	NA	NA	rs10761482-?	rs10761482	0	10761482	intron_variant	0	NR	8e-06	5.09691001300806		1.16	[NR]	Affymetrix [572888]	N
2009-07-24	19570815	Estrada K	2009-07-01	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19570815	A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.	Height	10,074 European ancestry individuals	6,912 European ancestry individuals	2q37.1	2	232290400	DIS3L2, ALPP, NPPC	DIS3L2			ENSG00000144535	NA	NA	rs6717918-T	rs6717918	0	6717918	intron_variant	0	0.78	3e-09	8.52287874528034		0.44	[0.20-0.68] cm increase	Affymetrix, Illumina, Perlegen [2228850] (imputed)	N
2009-07-24	19570815	Estrada K	2009-07-01	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19570815	A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.	Height	10,074 European ancestry individuals	6,912 European ancestry individuals	5p13.3	5	32888712	C5orf23, NPR3	AC010343.3			ENSG00000250697	NA	NA	rs10472828-C	rs10472828	0	10472828	non_coding_transcript_exon_variant	0	0.56	3e-07	6.52287874528034		0.22	[0.04-0.40] cm increase	Affymetrix, Illumina, Perlegen [2228850] (imputed)	N
2009-07-24	19570815	Estrada K	2009-07-01	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19570815	A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.	Height	10,074 European ancestry individuals	6,912 European ancestry individuals	22q13.1	22	40424147	SGSM3, MKL1	MRTFA			ENSG00000196588	NA	NA	rs5757949-T	rs5757949	0	5757949	intron_variant	0	NR	4e-06	5.39794000867204		NA		Affymetrix, Illumina, Perlegen [2228850] (imputed)	N
2009-07-24	19570815	Estrada K	2009-07-01	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19570815	A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.	Height	10,074 European ancestry individuals	6,912 European ancestry individuals	22q13.1	22	40301577	TNRC6B, ADSL	TNRC6B			ENSG00000100354	NA	NA	rs139909-T	rs139909	0	139909	intron_variant	0	0.68	2e-07	6.69897000433602		0.25	[0.03-0.47] cm increase	Affymetrix, Illumina, Perlegen [2228850] (imputed)	N
2009-07-24	19570815	Estrada K	2009-07-01	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19570815	A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.	Height	10,074 European ancestry individuals	6,912 European ancestry individuals	11q14.1	11	85453707	TMEM126B, TMEM126A	DLG2			ENSG00000150672	NA	NA	rs10898392-T	rs10898392	0	10898392	intron_variant	0	NR	3e-06	5.52287874528034		NA		Affymetrix, Illumina, Perlegen [2228850] (imputed)	N
2009-07-16	19578364	Bishop DT	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578364	Genome-wide association study identifies three loci associated with melanoma risk.	Melanoma	1,539 European ancestry cases, 3,917 European ancestry controls	2,312 European ancestry cases, 1,867 European ancestry controls	16q24.3	16	90000528	MC1R	AFG3L1P			ENSG00000223959	NA	NA	rs4785763-A	rs4785763	0	4785763	non_coding_transcript_exon_variant	0	0.32	6e-22	21.2218487496164		1.36	[1.28-1.45]	Illumina [~ 317000]	N
2009-07-16	19578364	Bishop DT	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578364	Genome-wide association study identifies three loci associated with melanoma risk.	Melanoma	1,539 European ancestry cases, 3,917 European ancestry controls	2,312 European ancestry cases, 1,867 European ancestry controls	9p21.3	9	21816529	CDKN2A	AL359922.1, MTAP			ENSG00000264545, ENSG00000099810	NA	NA	rs7023329-A	rs7023329	0	7023329	intron_variant	0	0.50	4e-07	6.39794000867204		1.18	[1.10-1.25]	Illumina [~ 317000]	N
2009-07-16	19578364	Bishop DT	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578364	Genome-wide association study identifies three loci associated with melanoma risk.	Melanoma	1,539 European ancestry cases, 3,917 European ancestry controls	2,312 European ancestry cases, 1,867 European ancestry controls	22q13.1	22	38148291	intergenic	AL022322.2, PLA2G6			ENSG00000279080, ENSG00000184381	NA	NA	rs2284063-?	rs2284063	0	2284063	non_coding_transcript_exon_variant	0	0.37	2e-09	8.69897000433602		1.2	[1.14-1.28]	Illumina [~ 317000]	N
2009-07-16	19578364	Bishop DT	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578364	Genome-wide association study identifies three loci associated with melanoma risk.	Melanoma	1,539 European ancestry cases, 3,917 European ancestry controls	2,312 European ancestry cases, 1,867 European ancestry controls	16q24.3	16	89689495	MC1R	CDK10			ENSG00000185324	NA	NA	rs258322-A	rs258322	0	258322	intron_variant	0	0.09	3e-27	26.5228787452803		1.67	[1.52-1.83]	Illumina [~ 317000]	N
2009-07-16	19578364	Bishop DT	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578364	Genome-wide association study identifies three loci associated with melanoma risk.	Melanoma	1,539 European ancestry cases, 3,917 European ancestry controls	2,312 European ancestry cases, 1,867 European ancestry controls	11q14.3	11	89277878	TYR	TYR			ENSG00000077498	NA	NA	rs1393350-A	rs1393350	0	1393350	intron_variant	0	0.27	2e-14	13.698970004336		1.29	[1.21-1.38]	Illumina [~ 317000]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	17q21.31	17	43729963	SOST	WHSC1L2P - SOST	ENSG00000267253	ENSG00000167941		9527	23775	rs1513670-A	rs1513670	0	1513670	intergenic_variant	1	0.37	2e-08	7.69897000433602		0.08	[0.05-0.10] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	11p11.2	11	46827809	LRP4	CKAP5			ENSG00000175216	NA	NA	rs1007738-A	rs1007738	0	1007738	intron_variant	0	0.77	7e-07	6.15490195998574		0.08	[0.05-0.11] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	3p22.1	3	41082244	NR	AC099541.1 - AC009743.1	ENSG00000233096	ENSG00000233919		110666	80043	rs10490823-G	rs10490823	0	10490823	intergenic_variant	1	0.46	9e-06	5.04575749056067		0.06	[0.03-0.09] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	17q21.31	17	44148179	C17orf53	C17orf53			ENSG00000125319	NA	NA	rs227584-T	rs227584	0	227584	missense_variant	0	0.73	9e-07	6.04575749056067		0.07	[0.04-0.10] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	6q25.1	6	151612040	ESR1	CCDC170			ENSG00000120262	NA	NA	rs1038304-G	rs1038304	0	1038304	intron_variant	0	0.47	4e-10	9.39794000867204		0.08	[0.06-0.11] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	2q12.1	2	103153780	NR	AC073987.1			ENSG00000229209	NA	NA	rs6735786-C	rs6735786	0	6735786	intron_variant	0	0.64	2e-06	5.69897000433602		0.07	[0.04-0.09] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	Xq21.2	X	86937000	NR	Z82210.1 - AL590229.2	ENSG00000236190	ENSG00000271457		48184	206854	rs2710057-T	rs2710057	0	2710057	intergenic_variant	1	0.67	1e-06	6		0.07	[0.04-0.09] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (hip)	6,865 European ancestry individuals	8,510 European ancestry individuals	1p36.12	1	22371954	intergenic	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		5472	56884	rs7524102-A	rs7524102	0	7524102	intergenic_variant	1	0.82	1e-16	16		0.15	[0.11-0.18] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	6q25.1	6	151615542	ESR1, C6orf97	CCDC170			ENSG00000120262	NA	NA	rs6929137-A	rs6929137	0	6929137	missense_variant	0	0.30	2e-10	9.69897000433602		0.1	[0.07-0.13] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	2p22.2	2	37817201	LOC344382	AC010878.1			ENSG00000225402	NA	NA	rs4670779-T	rs4670779	0	4670779	non_coding_transcript_exon_variant	0	0.32	4e-06	5.39794000867204		0.07	[0.04-0.10] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	1p36.12	1	22376365	intergenic	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		9883	52473	rs6696981-G	rs6696981	0	6696981	regulatory_region_variant	1	0.86	2e-08	7.69897000433602		0.12	[0.08-0.16] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	2p16.2	2	54457420	SPTBN1	SPTBN1			ENSG00000115306	NA	NA	rs11898505-G	rs11898505	0	11898505	intron_variant	0	0.68	4e-06	5.39794000867204		0.07	[0.04-0.10] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	12q13.13	12	53338107	SP7	SP7			ENSG00000170374	NA	NA	rs10876432-A	rs10876432	0	10876432	intron_variant	0	0.73	1e-07	7		0.08	[0.05-0.11] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	13q14.11	13	42458457	RANKL	LINC02341			ENSG00000283554	NA	NA	rs9594759-T	rs9594759	0	9594759	intron_variant	0	0.62	2e-17	16.698970004336		0.12	[0.09-0.15] s.d. decrease	Illumina [305051]	N
2009-01-16	19079262	Styrkarsdottir U	2008-12-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19079262	New sequence variants associated with bone mineral density.	Bone mineral density (spine)	6,865 European ancestry individuals	8,510 European ancestry individuals	21q11.2	21	14472731	NR	HSPA13 - SAMSN1	ENSG00000155304	ENSG00000155307		89247	12497	rs1006899-A	rs1006899	0	1006899	intergenic_variant	1	0.84	6e-06	5.22184874961636		0.09	[0.05-0.13] s.d. decrease	Illumina [305051]	N
2011-04-29	21459883	Villard E	2011-04-01	Eur Heart J	www.ncbi.nlm.nih.gov/pubmed/21459883	A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.	Idiopathic dilated cardiomyopathy	1,179 European ancestry cases, 1,108 European ancestry controls	1,165 European ancestry cases, 1,302 European ancestry controls	10q26.11	10	119670121	BAG3	BAG3			ENSG00000151929	NA	NA	rs2234962-?	rs2234962	0	2234962	missense_variant	0	NR	4e-12	11.397940008672		1.52	[1.22-1.89]	Illumina [517382]	N
2011-04-29	21459883	Villard E	2011-04-01	Eur Heart J	www.ncbi.nlm.nih.gov/pubmed/21459883	A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.	Idiopathic dilated cardiomyopathy	1,179 European ancestry cases, 1,108 European ancestry controls	1,165 European ancestry cases, 1,302 European ancestry controls	1p36.13	1	15972817	ZBTB17	ZBTB17			ENSG00000116809	NA	NA	rs10927875-?	rs10927875	0	10927875	intron_variant	0	NR	1e-09	9		1.32	[1.19-1.43]	Illumina [517382]	N
2010-03-12	20200953	Karasik D	2010-01-29	J Bone Miner Res	www.ncbi.nlm.nih.gov/pubmed/20200953	Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.	Osteoporosis-related phenotypes	2,073 related female individuals	NA	2q36.1	2	223409904	SCG2	HIGD1AP4 - AC013448.1	ENSG00000233299	ENSG00000231189		11358	88869	rs16864755-?	rs16864755	0	16864755	intergenic_variant	1		4e-06	5.39794000867204	(Femoral Neck BMD)	0.24	[0.14-0.34] cm3 increase	Affymetrix [433510]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	6p12.3	6	51295197	PKHD1	FTH1P5 - AL158050.2	ENSG00000230204	ENSG00000270306		381941	90085	rs1555967-?	rs1555967	0	1555967	intergenic_variant	1	NR	3e-06	5.52287874528034		NA		Affymetrix, Illumina [up to 512349]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	11p15.4	11	7687050	OVCH2	CYB5R2 - OVCH2	ENSG00000166394	ENSG00000183378		9828	2388	rs7932813-?	rs7932813	0	7932813	regulatory_region_variant	1	NR	5e-06	5.30102999566398		NA		Affymetrix, Illumina [up to 512349]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	18q21.32	18	60215554	MC4R	AC090771.1 - AC090621.1	ENSG00000267620	ENSG00000267401		17382	78582	rs489693-?	rs489693	0	489693	intergenic_variant	1	NR	4e-07	6.39794000867204		NA		Affymetrix, Illumina [up to 512349]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	14q31.1	14	79478819	NRXN3	NRXN3			ENSG00000021645	NA	NA	rs10146997-G	rs10146997	0	10146997	intron_variant	0	NR	5e-08	7.30102999566398		0.65	[NR] cm increase	Affymetrix, Illumina [up to 512349]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	5p14.3	5	21779045	CDH12	AC091946.1, CDH12			ENSG00000253766, ENSG00000154162	NA	NA	rs4701252-?	rs4701252	0	4701252	intron_variant	0	NR	2e-06	5.69897000433602		NA		Affymetrix, Illumina [up to 512349]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	12q13.12	12	49853685	BCDIN3D, FAIM2	BCDIN3D - AC131157.1	ENSG00000186666	ENSG00000257253		10579	7522	rs7138803-?	rs7138803	0	7138803	intergenic_variant	1	NR	8e-07	6.09691001300806		NA		Affymetrix, Illumina [up to 512349]	N
2009-07-01	19557197	Heard-Costa NL	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557197	NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.	Waist circumference	31,373 European ancestry individuals	38,641 individuals	16q12.2	16	53769662	FTO	FTO			ENSG00000140718	NA	NA	rs1558902-?	rs1558902	0	1558902	intron_variant	0	NR	5e-19	18.301029995664		NA		Affymetrix, Illumina [up to 512349]	N
2008-06-16	18385738	Hung RJ	2008-04-03	Nature	www.ncbi.nlm.nih.gov/pubmed/18385738	A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.	Lung cancer	1,926 European ance other ancestry cases, 2,522 European and other ancestry controls	332 European ancestry cases, 462 European ancestry controls, 2,181 European and other ancestry cases, 4,290 European and other ancestry controls	15q25.1	15	78513681	CHRNA5, CHRNA3, PSMA4, LOC123688, CHRNB4	HYKK			ENSG00000188266	NA	NA	rs8034191-C	rs8034191	0	8034191	intron_variant	0	0.34	5e-20	19.301029995664		1.3	[1.23-1.37]	Illumina [310023]	N
2010-09-10	20668430	Genovese G	2010-07-28	Kidney Int	www.ncbi.nlm.nih.gov/pubmed/20668430	A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.	Glomerulosclerosis	56 African American cases, 61 European ancestry cases, 1,759 African American controls, 1,531 European ancestry controls	299 European ancestry cases	22q12.3	22	36265284	APOL1, MYH9	APOL1			ENSG00000100342	NA	NA	rs2239785-G	rs2239785	0	2239785	missense_variant	0	0.64	5e-13	12.301029995664	(AA)	NA		Illumina [up to 542539]	N
2008-06-16	18385676	Amos CI	2008-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18385676	Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.	Lung cancer	1,154 European ancestry cases, 1,137 European ancestry controls	2,724 European ancestry cases, 3,694 European ancestry controls	15q25.1	15	78513681	CHRNA5, CHRNA3, PSMA4, LOC123688	HYKK			ENSG00000188266	NA	NA	rs8034191-G	rs8034191	0	8034191	intron_variant	0	NR	3e-18	17.5228787452803		1.3	[1.15-1.47]	Illumina [317498]	N
2008-06-16	18385676	Amos CI	2008-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18385676	Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.	Lung cancer	1,154 European ancestry cases, 1,137 European ancestry controls	2,724 European ancestry cases, 3,694 European ancestry controls	3q28	3	190632672	IL1RAP	IL1RAP			ENSG00000196083	NA	NA	rs7626795-G	rs7626795	0	7626795	intron_variant	0	NR	8e-06	5.09691001300806		1.16	[1.05-1.28]	Illumina [317498]	N
2008-06-16	18385676	Amos CI	2008-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18385676	Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.	Lung cancer	1,154 European ancestry cases, 1,137 European ancestry controls	2,724 European ancestry cases, 3,694 European ancestry controls	1q23.2	1	159711078	CRP	CRPP1 - CRP	ENSG00000223603	ENSG00000132693		5471	1211	rs2808630-G	rs2808630	0	2808630	intergenic_variant	1	NR	7e-06	5.15490195998574		1.22	[1.10-1.35]	Illumina [317498]	N
2009-07-13	19578365	Falchi M	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578365	Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.	Cutaneous nevi	1,524 European ancestry twins	4,107 European ancestry individuals, 3,131 European ancestry cases, 4,276 European ancestry controls	9p21.3	9	21747804	MTAP	RN7SL151P - MTAP	ENSG00000244230	ENSG00000099810		48208	54832	rs4636294-A	rs4636294	0	4636294	intergenic_variant	1	0.48	3e-15	14.5228787452803		0.2	[0.13-0.27] log nevus count increase	Illumina [297108]	N
2009-07-13	19578365	Falchi M	2009-07-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19578365	Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi.	Cutaneous nevi	1,524 European ancestry twins	4,107 European ancestry individuals, 3,131 European ancestry cases, 4,276 European ancestry controls	22q13.1	22	38148291	PLA2G6	AL022322.2, PLA2G6			ENSG00000279080, ENSG00000184381	NA	NA	rs2284063-G	rs2284063	0	2284063	non_coding_transcript_exon_variant	0	0.35	3e-08	7.52287874528034		0.08	[-0.002-0.16] log nevus count decrease	Illumina [297108]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	1q31.3	1	197812068	DENND1B	DENND1B - C1orf53	ENSG00000213047	ENSG00000203724		36372	90562	rs12134279-T	rs12134279	0	12134279	regulatory_region_variant	1	0.20	2e-14	13.698970004336		1.34	[1.25-1.45]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	5p13.2	5	35942940	IL7R	AC112204.2 - UGT3A1	ENSG00000249748	ENSG00000145626		2947	8066	rs860413-A	rs860413	0	860413	intergenic_variant	1	0.72	1e-11	11		1.3	[1.21-1.40]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	7p14.1	7	37334906	intergenic	ELMO1			ENSG00000155849	NA	NA	rs6974491-A	rs6974491	0	6974491	intron_variant	0	0.17	4e-08	7.39794000867204		1.25	[1.16-1.36]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	7q32.1	7	128977412	IRF5	TNPO3			ENSG00000064419	NA	NA	rs12531711-G	rs12531711	0	12531711	intron_variant	0	0.11	9e-17	16.0457574905607		1.58	[1.41-1.76]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	19q13.33	19	50423485	SPIB	SPIB, AC020909.1			ENSG00000269404, ENSG00000142539	NA	NA	rs3745516-A	rs3745516	0	3745516	intron_variant	0	0.23	2e-13	12.698970004336		1.38	[1.32-1.44]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	12p13.31	12	6330843	TNFRSF1A	TNFRSF1A			ENSG00000067182	NA	NA	rs1800693-C	rs1800693	0	1800693	non_coding_transcript_exon_variant	0	0.40	2e-09	8.69897000433602		1.22	[1.14-1.30]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	16p13.13	16	11093926	CLEC16A	CLEC16A			ENSG00000038532	NA	NA	rs12924729-G	rs12924729	0	12924729	intron_variant	0	0.68	3e-12	11.5228787452803		1.29	[1.20-1.38]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	16q24.1	16	85985665	intergenic	AC092723.4 - AC092723.3	ENSG00000285040	ENSG00000285012		279	1099	rs11117432-G	rs11117432	0	11117432	intergenic_variant	1	0.76	5e-11	10.301029995664		1.31	[1.21-1.43]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	3q25.33	3	160028076	IL12A	LINC01100, IL12A-AS1			ENSG00000242107, ENSG00000244040	NA	NA	rs485499-T	rs485499	0	485499	intron_variant	0	0.57	2e-16	15.698970004336		1.38	[1.28-1.50]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	6p21.32	6	32689801	MHC	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		21418	16323	rs7774434-C	rs7774434	0	7774434	TF_binding_site_variant	1	0.38	4e-34	33.397940008672		1.6	[1.48-1.73]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	3q13.33	3	119501087	CD80	TIMMDC1			ENSG00000113845	NA	NA	rs2293370-G	rs2293370	0	2293370	intron_variant	0	0.80	3e-11	10.5228787452803		1.35	[1.23-1.47]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	2q32.2	2	190673836	STAT4	NAB1			ENSG00000138386	NA	NA	rs10931468-A	rs10931468	0	10931468	intron_variant	0	0.12	2e-19	18.698970004336		1.5	[1.37-1.64]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	4q24	4	102630446	NFKB1	NFKB1 - MANBA	ENSG00000109320	ENSG00000109323		13144	324	rs7665090-C	rs7665090	0	7665090	regulatory_region_variant	1	0.52	4e-12	11.397940008672		1.26	[1.18-1.34]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	11q23.3	11	118873063	CXCR5	Y_RNA - Y_RNA	ENSG00000265852	ENSG00000265852		36952	97435	rs6421571-C	rs6421571	0	6421571	intergenic_variant	1	0.81	3e-12	11.5228787452803		1.37	[1.25-1.50]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	14q24.1	14	68286876	RAD51L1	RAD51B			ENSG00000182185	NA	NA	rs911263-T	rs911263	0	911263	intron_variant	0	0.71	2e-11	10.698970004336		1.29	[1.20-1.39]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	22q13.1	22	39274846	MAP3K7IP1	AL031590.1			ENSG00000284633	NA	NA	rs968451-T	rs968451	0	968451	intron_variant	0	0.19	1e-09	9		1.27	[1.18-1.38]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	1p31.3	1	67324915	IL12RB2	IL12RB2			ENSG00000081985	NA	NA	rs17129789-C	rs17129789	0	17129789	intron_variant	0	0.18	9e-20	19.0457574905607		1.52	[1.39-1.67]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	17q12	17	39387196	ORMDL3	FBXL20			ENSG00000108306	NA	NA	rs7208487-T	rs7208487	0	7208487	intron_variant	0	0.84	8e-07	6.09691001300806		1.32	[1.18-1.48]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	3p24.3	3	16913767	PLCL2	PLCL2, PLCL2			ENSG00000154822, ENSG00000284017	NA	NA	rs1372072-A	rs1372072	0	1372072	intron_variant	0	0.37	2e-08	7.69897000433602		1.2	[1.12-1.27]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	11q13.1	11	64362250	RPS6KA4	RPS6KA4			ENSG00000162302	NA	NA	rs538147-G	rs538147	0	538147	intron_variant	0	0.61	2e-10	9.69897000433602		1.23	[1.15-1.31]	Illumina [507467]	N
2011-04-12	21399635	Mells GF	2011-03-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21399635	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.	Primary biliary cholangitis	1,840 European ancestry cases, 5,163 European ancestry controls and (Liu et al)	620 European ancestry cases, 2,514 European ancestry controls	14q32.32	14	103096858	TNFAIP2	AL161669.1			ENSG00000259444	NA	NA	rs8017161-A	rs8017161	0	8017161	intron_variant	0	0.40	3e-13	12.5228787452803		1.22	[1.16-1.27]	Illumina [507467]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	1q23.3	1	161509955	FCGR2A	FCGR2A			ENSG00000143226	NA	NA	rs1801274-?	rs1801274	0	1801274	missense_variant	0	0.78	2e-12	11.698970004336		1.59	[1.39-1.82]	Illumina [513923]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	6p21.33	6	31143579	HLA	CCHCR1, CCHCR1, CCHCR1, CCHCR1, CCHCR1, CCHCR1			ENSG00000204536, ENSG00000223533, ENSG00000206457, ENSG00000206355, ENSG00000224180, ENSG00000234114	NA	NA	rs9263739-T	rs9263739	0	9263739	intron_variant	0	0.15	4e-67	66.397940008672		2.73	[2.43-3.07]	Illumina [513923]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	13q12.13	13	26957130	USP12	FGFR1OP2P1 - AL160035.1	ENSG00000230256	ENSG00000283579		51269	8837	rs17085007-C	rs17085007	0	17085007	regulatory_region_variant	1	0.23	7e-08	7.15490195998574		1.35	[1.21-1.51]	Illumina [513923]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	9p24.1	9	5213687	INSL6, INSL4, JAK2	AL133547.1 - INSL4	ENSG00000237553	ENSG00000120211		20129	17732	rs10975003-C	rs10975003	0	10975003	intergenic_variant	1	0.19	1e-06	6		1.34	[1.18-1.51]	Illumina [513923]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	6p21.32	6	32465390	intergenic	HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9			ENSG00000234164, ENSG00000232705, ENSG00000228260, ENSG00000227526, ENSG00000196301, ENSG00000227384, ENSG00000237591, ENSG00000226035	NA	NA	rs2395185-G	rs2395185	0	2395185	intron_variant	0	0.61	5e-22	21.301029995664		1.92	[1.68-2.19]	Illumina [513923]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	7q31.1	7	107812658	SLC26A3	PIGCP2 - DLD	ENSG00000229626	ENSG00000091140		3090	78504	rs2108225-A	rs2108225	0	2108225	intergenic_variant	1	0.65	1e-07	7		1.32	[1.19-1.47]	Illumina [513923]	N
2009-12-14	19915573	Asano K	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915573	A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population.	Ulcerative colitis	376 Japanese ancestry cases, 934 Japanese ancestry controls	376 Japanese ancestry cases, 1,097 Japanese ancestry controls	6p21.32	6	32396067	BTNL2	BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, TSBP1-AS1			ENSG00000226127, ENSG00000225412, ENSG00000204290, ENSG00000225845, ENSG00000229741, ENSG00000224770, ENSG00000229597, ENSG00000224242, ENSG00000225914	NA	NA	rs9268480-G	rs9268480	0	9268480	synonymous_variant	0	0.91	3e-06	5.52287874528034		1.82	[1.43-2.33]	Illumina [513923]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	10q25.1	10	104086316	COL17A1	COL17A1 - SFR1	ENSG00000065618	ENSG00000156384		436	35742	rs1320448-?	rs1320448	0	1320448	intergenic_variant	1	NR	2e-08	7.69897000433602	(additive, recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	1q41	1	216543195	ESRRG	ESRRG			ENSG00000196482	NA	NA	rs12757165-?	rs12757165	0	12757165	intron_variant	0	NR	1e-07	7	(additive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	1p34.2	1	43130713	SLC2A1	AL161637.1 - FAM183A	ENSG00000277513	ENSG00000186973		26216	14440	rs16830359-?	rs16830359	0	16830359	intergenic_variant	1	NR	1e-07	7	(additive, recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	10q21.1	10	55657201	ZWINT	PCDH15 - GAPDHP21	ENSG00000150275	ENSG00000236993		29259	10140	rs1916521-?	rs1916521	0	1916521	intergenic_variant	1	NR	5e-07	6.30102999566398	(recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	3q13.13	3	109485566	DPPA4	LINC01205			ENSG00000228980	NA	NA	rs769554-?	rs769554	0	769554	intron_variant	0	NR	3e-06	5.52287874528034	(additive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	13q14.2	13	47624581	HTR2A	RN7SL700P - SUCLA2	ENSG00000244521	ENSG00000136143		165347	121155	rs1575891-?	rs1575891	0	1575891	intergenic_variant	1	NR	6e-06	5.22184874961636	(additive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	5q31.3	5	142638295	FGF1	FGF1, SPRY4-AS1			ENSG00000113578, ENSG00000231185	NA	NA	rs152528-?	rs152528	0	152528	intron_variant	0	NR	8e-07	6.09691001300806	(recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	8q12.1	8	60091338	CA8	AC021393.1			ENSG00000254775	NA	NA	rs6995588-?	rs6995588	0	6995588	intron_variant	0	NR	2e-06	5.69897000433602	(additive,  dominant)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	6q16.3	6	103984290	GRIK2	AL590608.1 - R3HDM2P2	ENSG00000288084	ENSG00000216817		109603	33343	rs4520040-?	rs4520040	0	4520040	intergenic_variant	1	NR	3e-06	5.52287874528034	(additive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	1q32.2	1	208584241	PLXNA2	AL606753.2 - LINC01735	ENSG00000286198	ENSG00000261453		313574	22323	rs17259784-?	rs17259784	0	17259784	intergenic_variant	1	NR	6e-06	5.22184874961636	(recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	13q14.2	13	49506711	PHF11	PHF11			ENSG00000136147	NA	NA	rs2031532-?	rs2031532	0	2031532	synonymous_variant	0	NR	5e-06	5.30102999566398	(recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	15q12	15	25667192	UBE3A	AC023449.1 - ATP10A	ENSG00000223628	ENSG00000206190		86070	10081	rs17636733-?	rs17636733	0	17636733	intergenic_variant	1	NR	2e-07	6.69897000433602	(recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	12q14.1	12	60403922	FAM19A2	AC090022.1 - AC090022.2	ENSG00000251822	ENSG00000257865		39987	15061	rs10506410-?	rs10506410	0	10506410	intergenic_variant	1	NR	2e-06	5.69897000433602	(dominant)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	6p22.1	6	30125587	TRIM38	TRIM31-AS1 - AL669914.1	ENSG00000229223	ENSG00000252228		10863	7218	rs10947055-?	rs10947055	0	10947055	intergenic_variant	1	NR	2e-07	6.69897000433602	(additive, recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	10q23.1	10	80939735	NRG3	FARSBP1 - WARS2P1	ENSG00000231060	ENSG00000227209		161647	930	rs1484170-?	rs1484170	0	1484170	intergenic_variant	1	NR	1e-06	6	(additive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	6p22.3	6	22246375	SOX4	CASC15			ENSG00000272168	NA	NA	rs4236016-?	rs4236016	0	4236016	intron_variant	0	NR	4e-06	5.39794000867204	(additive, recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	3p25.2	3	12585017	RAF1	RAF1			ENSG00000132155	NA	NA	rs3729931-?	rs3729931	0	3729931	intron_variant	0	NR	7e-07	6.15490195998574	(dominant)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	15q14	15	39023157	C15orf54	AC013652.1, LINC02694, AC087878.1			ENSG00000259345, ENSG00000175779, ENSG00000259278	NA	NA	rs12907914-?	rs12907914	0	12907914	intron_variant	0	NR	1e-06	6	(recessive)	NA		Affymetrix [361034]	N
2011-03-28	21348951	Parsa A	2011-02-01	Clin Transl Sci	www.ncbi.nlm.nih.gov/pubmed/21348951	Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.	Cardiac hypertrophy	851 Old Order Amish individuals	NA	20p12.2	20	11194255	C20orf94, BTBD3, SNAP25, MKK5, JAG1	C20orf187 - AL049649.1	ENSG00000125899	ENSG00000230990		164800	39915	rs2207418-?	rs2207418	0	2207418	intergenic_variant	1	NR	9e-06	5.04575749056067	(dominant)	NA		Affymetrix [361034]	N
2009-07-01	19557161	Lindgren CM	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557161	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.	Adiposity	38,580 European ancestry individuals	Up to 102,064 European ancestry individuals	1q41	1	219470882	LYPLAL1	LYPLAL1-AS1 - AL356364.1	ENSG00000228536	ENSG00000238232		11513	86310	rs2605100-G	rs2605100	0	2605100	intergenic_variant	1	0.692	3e-08	7.52287874528034	(WHR in women)	0.04	[0.03-0.05] z-score unit increase	Affymetrix, Illumina [2573738] (imputed)	N
2009-07-01	19557161	Lindgren CM	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557161	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.	Adiposity	38,580 European ancestry individuals	Up to 102,064 European ancestry individuals	8p23.1	8	10002570	MSRA	AC034111.2			ENSG00000286622	NA	NA	rs7826222-G	rs7826222	1	545854	intron_variant	0	0.183	9e-09	8.04575749056067	(WC)	0.04	[0.03-0.05] z-score unit increase	Affymetrix, Illumina [2573738] (imputed)	N
2009-07-01	19557161	Lindgren CM	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557161	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.	Adiposity	38,580 European ancestry individuals	Up to 102,064 European ancestry individuals	6p12.3	6	50835337	TFAP2B	TFAP2B			ENSG00000008196	NA	NA	rs987237-G	rs987237	0	987237	intron_variant	0	0.164	2e-11	10.698970004336	(WC)	0.04	[0.03-0.05] z-score unit increase	Affymetrix, Illumina [2573738] (imputed)	N
2009-07-01	19557161	Lindgren CM	2009-06-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19557161	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.	Adiposity	38,580 European ancestry individuals	Up to 102,064 European ancestry individuals	1q42.3	1	235436814	TBCE	TBCE, TBCE, TBCE			ENSG00000284770, ENSG00000285053, ENSG00000282984	NA	NA	rs6429082-C	rs6429082	0	6429082	intron_variant	0	0.46	3e-07	6.52287874528034	(WC)	NA		Affymetrix, Illumina [2573738] (imputed)	N
2009-09-29	19734902	Harold D	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734902	Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.	Alzheimer's disease	3,941 European ancestry cases, 7,848 European ancestry controls	2,023 European ancestry cases, 2,340 European ancestry controls	8p21.1	8	27607002	CLU	CLU			ENSG00000120885	NA	NA	rs11136000-?	rs11136000	0	11136000	intron_variant	0	0.60	9e-10	9.04575749056067		1.16	[1.11-1.22]	Illumina [529205]	N
2009-09-29	19734902	Harold D	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734902	Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.	Alzheimer's disease	3,941 European ancestry cases, 7,848 European ancestry controls	2,023 European ancestry cases, 2,340 European ancestry controls	11q14.2	11	86157598	PICALM	RNU6-560P - LINC02695	ENSG00000200877	ENSG00000254699		4264	35189	rs3851179-?	rs3851179	0	3851179	regulatory_region_variant	1	0.63	1e-09	9		1.16	[1.11-1.22]	Illumina [529205]	N
2009-09-29	19734902	Harold D	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734902	Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.	Alzheimer's disease	3,941 European ancestry cases, 7,848 European ancestry controls	2,023 European ancestry cases, 2,340 European ancestry controls	19q13.32	19	44892362	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	0	0.15	2e-157	156.698970004336		2.53	[2.37-2.71]	Illumina [529205]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	3p25.1	3	15399049	NR	METTL6			ENSG00000206562	NA	NA	rs6442522-?	rs6442522	0	6442522	intron_variant	0	NR	5e-06	5.30102999566398		0.05	[NR] mg/dl increase in uric acid levels	Affymetrix [361034]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	4p16.1	4	9920543	GLUT9	SLC2A9			ENSG00000109667	NA	NA	rs16890979-?	rs16890979	0	16890979	missense_variant	0	NR	1e-11	11		0.44	[0.32-0.56] mg/dl decrease in uric serum levels	Affymetrix [361034]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	13q33.1	13	103317141	NR	SLC10A2 - AL162717.1	ENSG00000125255	ENSG00000285789		250724	26519	rs4771450-?	rs4771450	0	4771450	intergenic_variant	1	NR	2e-06	5.69897000433602		0.23	[NR] mg/dl decrease in uric acid levels	Affymetrix [361034]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	2q31.1	2	170876715	NR	GAD1 - AC010092.1	ENSG00000128683	ENSG00000286115		15564	13678	rs4668338-?	rs4668338	0	4668338	intergenic_variant	1	NR	3e-06	5.52287874528034		4.29	[NR] mg/dl decrease in uric acid levels	Affymetrix [361034]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	20p12.3	20	7199409	NR	LINC01428			ENSG00000228888	NA	NA	rs6085920-?	rs6085920	0	6085920	intron_variant	0	NR	6e-06	5.22184874961636		0.4	[NR] mg/dl decrease in uric acid levels	Affymetrix [361034]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	5q31.3	5	143062229	NR	ARHGAP26			ENSG00000145819	NA	NA	rs3776331-?	rs3776331	0	3776331	intron_variant	0	NR	8e-06	5.09691001300806		0.3	[NR] mg/dl increase in uric acid levels	Affymetrix [361034]	N
2008-10-14	18759275	McArdle PF	2008-09-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18759275	Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish.	Uric acid levels	408 Old Order Amish female individuals, 460 Old Order Amish male individuals	Framingham Heart Study (Sample size NR)	13q14.11	13	44053652	NR	NRAD1 - LINC00390	ENSG00000233725	ENSG00000226519		23191	41170	rs17065323-?	rs17065323	0	17065323	regulatory_region_variant	1	NR	4e-06	5.39794000867204		4.29	[NR] mg/dl decrease in uric acid levels	Affymetrix [361034]	N
2008-10-14	18463975	Kibriya MG	2008-05-08	Breast Cancer Res Treat	www.ncbi.nlm.nih.gov/pubmed/18463975	A pilot genome-wide association study of early-onset breast cancer.	Breast cancer	26 European ancestry cases, 3 Hispanic cases, 1 African American case, 26 European ancestry controls, 3 Hispanic controls, 1 African American control	NA	16q23.1	16	74438798	GLG1	No mapped genes; No mapped genes; AC009053.3				NA	NA	SNP_A-2032347-?; SNP_A-2196879-?; rs10871290-?	SNP_A-2032347; SNP_A-2196879; rs10871290	0	NA	intron_variant	NA	0.34	4e-07	6.39794000867204		NA		Affymetrix [200220]	N
2013-03-27	23359319	Jin G	2013-01-01	Neoplasia	www.ncbi.nlm.nih.gov/pubmed/23359319	Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.	Prostate-specific antigen levels	3,192 European ancestry individuals	1,722 European ancestry individuals	12p13.1	12	14434367	ATF7IP	ATF7IP			ENSG00000171681	NA	NA	rs3213764-G	rs3213764	0	3213764	missense_variant	0	0.467	2e-09	8.69897000433602		0.049	% increase	Illumina [642584]	N
2013-03-27	23359319	Jin G	2013-01-01	Neoplasia	www.ncbi.nlm.nih.gov/pubmed/23359319	Genome-wide association study identifies loci at ATF7IP and KLK2 associated with percentage of circulating free PSA.	Prostate-specific antigen levels	3,192 European ancestry individuals	1,722 European ancestry individuals	19q13.33	19	50889862	KLK2, KLKP1	KLKP1			ENSG00000197588	NA	NA	rs1354774-G	rs1354774	0	1354774	intron_variant	0	0.343	6e-20	19.2218487496164		0.058	% increase	Illumina [642584]	N
2009-01-14	19074352	Pollin TI	2008-12-17	Science	www.ncbi.nlm.nih.gov/pubmed/19074352	A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection.	Triglycerides	809 Old Order Amish individuals	698 Old Order Amish individuals	11q23.3	11	117661016	APOA1, APOC3, APOA4, APOA5, DSCAML1	DSCAML1			ENSG00000177103	NA	NA	rs10892151-A	rs10892151	0	10892151	intron_variant	0	0.028	3e-29	28.5228787452803		NA		Affymetrix [381934]	N
2008-11-11	18840781	Grant SF	2008-10-07	Diabetes	www.ncbi.nlm.nih.gov/pubmed/18840781	Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.	Type 1 diabetes	563 European ancestry cases, 1,146 European ancestry controls, 483 European ancestry trios	3,303 European ancestry cases, 4,673 European ancestry controls	6q15	6	90247744	BACH2	BACH2			ENSG00000112182	NA	NA	rs3757247-A	rs3757247	0	3757247	intron_variant	0	NR	1e-06	6		1.13	[1.08-1.19]	Illumina [up to 1000000]	N
2008-11-11	18840781	Grant SF	2008-10-07	Diabetes	www.ncbi.nlm.nih.gov/pubmed/18840781	Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.	Type 1 diabetes	563 European ancestry cases, 1,146 European ancestry controls, 483 European ancestry trios	3,303 European ancestry cases, 4,673 European ancestry controls	15q14	15	38546063	RASGRP1	RASGRP1			ENSG00000172575	NA	NA	rs8035957-C	rs8035957	0	8035957	intron_variant	0	NR	4e-06	5.39794000867204		1.14	[1.08-1.21]	Illumina [up to 1000000]	N
2008-11-11	18840781	Grant SF	2008-10-07	Diabetes	www.ncbi.nlm.nih.gov/pubmed/18840781	Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.	Type 1 diabetes	563 European ancestry cases, 1,146 European ancestry controls, 483 European ancestry trios	3,303 European ancestry cases, 4,673 European ancestry controls	21q22.3	21	42416281	UBASH3A	UBASH3A			ENSG00000160185	NA	NA	rs9976767-C	rs9976767	0	9976767	intron_variant	0	NR	2e-08	7.69897000433602		1.16	[1.10-1.22]	Illumina [up to 1000000]	N
2008-11-11	18840781	Grant SF	2008-10-07	Diabetes	www.ncbi.nlm.nih.gov/pubmed/18840781	Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.	Type 1 diabetes	563 European ancestry cases, 1,146 European ancestry controls, 483 European ancestry trios	3,303 European ancestry cases, 4,673 European ancestry controls	1p22.3	1	84845509	EDG7	LPAR3			ENSG00000171517	NA	NA	rs1983853-?	rs1983853	0	1983853	intron_variant	0	NR	2e-06	5.69897000433602		1.2	[1.11-1.29]	Illumina [up to 1000000]	N
2008-11-11	18840781	Grant SF	2008-10-07	Diabetes	www.ncbi.nlm.nih.gov/pubmed/18840781	Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.	Type 1 diabetes	563 European ancestry cases, 1,146 European ancestry controls, 483 European ancestry trios	3,303 European ancestry cases, 4,673 European ancestry controls	9p24.2	9	4292083	GLIS3	GLIS3			ENSG00000107249	NA	NA	rs10758593-A	rs10758593	0	10758593	intron_variant	0	NR	3e-06	5.52287874528034		1.13	[1.07-1.19]	Illumina [up to 1000000]	N
2008-11-12	18823527	Abraham R	2008-09-29	BMC Med Genomics	www.ncbi.nlm.nih.gov/pubmed/18823527	A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.	Alzheimer's disease	1,082 European ancestry cases, 1,239 European ancestry controls	1,400 controls	19q13.32	19	44878777	APOE, PVRL2, TOMM40	NECTIN2			ENSG00000130202	NA	NA	rs6859-A	rs6859	0	6859	3_prime_UTR_variant	0	NR	6e-14	13.2218487496164		NA		Illumina [561494]	N
2008-11-12	18823527	Abraham R	2008-09-29	BMC Med Genomics	www.ncbi.nlm.nih.gov/pubmed/18823527	A genome-wide association study for late-onset Alzheimer's disease using DNA pooling.	Alzheimer's disease	1,082 European ancestry cases, 1,239 European ancestry controls	1,400 controls	4q32.1	4	154733269	intergenic	LRAT			ENSG00000121207	NA	NA	rs727153-C	rs727153	0	727153	intron_variant	0	0.52	3e-06	5.52287874528034		1.63	[1.37-1.95]	Illumina [561494]	N
2008-06-16	17553421	Reiman EM	2007-06-07	Neuron	www.ncbi.nlm.nih.gov/pubmed/17553421	GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.	Alzheimer's disease (late onset)	446 cases, 290 controls	415 cases, 260 controls	11q14.1	11	78380104	GAB2	AP003086.1, GAB2			ENSG00000254420, ENSG00000033327	NA	NA	rs2373115-G	rs2373115	0	2373115	intron_variant	0	0.70	1e-10	10		4.06	[2.81-14.69]	Affymetrix [312316]	N
2009-04-02	19304780	Org E	2009-03-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19304780	Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations.	Hypertension	364 European ancestry cases, 590 European ancestry controls	1,043 European ancestry cases, 1,769 European ancestry controls	16q23.3	16	82609046	CDH13	AC009117.2 - CDH13	ENSG00000261285	ENSG00000140945		33528	17919	rs11646213-T	rs11646213	0	11646213	intergenic_variant	1	0.60	8e-06	5.09691001300806		1.28	[1.15-1.43]	Affymetrix [395912]	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood insulin	38,238 European ancestry individuals	62,264 European ancestry individuals	12q23.2	12	102481791	IGF1	IGF1 - AC010202.1	ENSG00000017427	ENSG00000257254		47	31460	rs35767-G	rs35767	0	35767	intergenic_variant	1	0.85	3e-08	7.52287874528034		0.01	[-0.00176-0.02176] pmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood insulin	38,238 European ancestry individuals	62,264 European ancestry individuals	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-C	rs780094	0	780094	intron_variant	0	0.62	4e-20	19.397940008672		0.032	[0.024-0.04] pmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	2q31.1	2	168906638	G6PC2	SPC25, SPC25, G6PC2, G6PC2			ENSG00000152253, ENSG00000277909, ENSG00000152254, ENSG00000278373	NA	NA	rs560887-C	rs560887	0	560887	intron_variant	0	0.7	9e-218	217.045757490561		0.075	[0.069-0.081] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	15q22.2	15	62141763	C2CD4B	NPM1P47 - C2CD4B	ENSG00000259466	ENSG00000205502		58458	21772	rs11071657-A	rs11071657	0	11071657	regulatory_region_variant	1	0.63	4e-08	7.39794000867204		0.008	[0.0021-0.0139] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	8q24.11	8	117173494	SLC30A8	SLC30A8			ENSG00000164756	NA	NA	rs11558471-A	rs11558471	0	11558471	3_prime_UTR_variant	0	0.31	3e-11	10.5228787452803		NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	10q25.2	10	112996282	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs4506565-T	rs4506565	0	4506565	intron_variant	0	0.31	1e-08	8		NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	7p13	7	44196069	GCK	GCK			ENSG00000106633	NA	NA	rs4607517-A	rs4607517	0	4607517	intron_variant	0	0.16	7e-92	91.1549019599858		0.062	[0.054-0.07] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	3q26.2	3	170999732	SLC2A2	AC061708.1, SLC2A2			ENSG00000286856, ENSG00000163581	NA	NA	rs11920090-T	rs11920090	0	11920090	intron_variant	0	0.87	8e-13	12.0969100130081		0.02	[0.012-0.028] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	7p21.2	7	15024684	TMEM195, DGKB	GTF3AP5 - AC006458.1	ENSG00000225816	ENSG00000227489		38610	41523	rs2191349-T	rs2191349	0	2191349	intergenic_variant	1	0.52	3e-44	43.5228787452803		0.03	[0.024-0.036] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-C	rs780094	0	780094	intron_variant	0	0.62	6e-38	37.2218487496164		0.029	[0.023-0.035] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	3q21.1	3	123346931	ADCY5	ADCY5			ENSG00000173175	NA	NA	rs11708067-A	rs11708067	0	11708067	intron_variant	0	0.78	7e-22	21.1549019599857		0.027	[0.021-0.033] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	11p11.2	11	47314769	MADD	MADD			ENSG00000110514	NA	NA	rs7944584-A	rs7944584	0	7944584	intron_variant	0	0.75	2e-18	17.698970004336		0.021	[0.015-0.027] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	10q25.2	10	111282335	ADRA2A	AL355863.1 - BTBD7P2	ENSG00000213247	ENSG00000237618		177087	40443	rs10885122-G	rs10885122	0	10885122	intergenic_variant	1	0.87	3e-16	15.5228787452803		0.022	[0.014-0.03] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	11q12.2	11	61804006	FADS1	FADS2, FADS1			ENSG00000134824, ENSG00000149485	NA	NA	rs174550-T	rs174550	0	174550	5_prime_UTR_variant	0	0.64	2e-15	14.698970004336		0.017	[0.011-0.023] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	9p24.2	9	4289050	GLIS3	GLIS3			ENSG00000107249	NA	NA	rs7034200-A	rs7034200	0	7034200	intron_variant	0	0.49	1e-12	12		0.018	[0.012-0.024] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	1q32.3	1	213985913	PROX1	PROX1, PROX1-AS1, AC011700.1			ENSG00000117707, ENSG00000230461, ENSG00000274895	NA	NA	rs340874-C	rs340874	0	340874	non_coding_transcript_exon_variant	0	0.52	7e-12	11.1549019599857		0.013	[0.0071-0.0189] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	11q14.3	11	92975544	MTNR1B	MTNR1B			ENSG00000134640	NA	NA	rs10830963-G	rs10830963	0	10830963	intron_variant	0	0.3	6e-175	174.221848749616		0.067	[0.061-0.073] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-28	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Fasting blood glucose	46,186 European ancestry individuals	76,558 European ancestry individuals	11p11.2	11	45851540	CRY2	CRY2			ENSG00000121671	NA	NA	rs11605924-A	rs11605924	0	11605924	intron_variant	0	0.49	1e-14	14		0.015	[0.0091-0.0209] mmol/L increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of insulin resistance	37,037 European ancestry individuals	62,264 European ancestry individuals	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-C	rs780094	0	780094	intron_variant	0	0.62	3e-24	23.5228787452803		0.035	[0.027-0.043] unit increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of insulin resistance	37,037 European ancestry individuals	62,264 European ancestry individuals	12q23.2	12	102481791	IGF1	IGF1 - AC010202.1	ENSG00000017427	ENSG00000257254		47	31460	rs35767-G	rs35767	0	35767	intergenic_variant	1	0.85	2e-09	8.69897000433602		0.013	[0.0012-0.0248] unit increase (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	2q31.1	2	168906638	G6PC2	SPC25, SPC25, G6PC2, G6PC2			ENSG00000152253, ENSG00000277909, ENSG00000152254, ENSG00000278373	NA	NA	rs560887-C	rs560887	0	560887	intron_variant	0	0.7	2e-66	65.698970004336		0.042	[0.034-0.05] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	11q14.3	11	92975544	MTNR1B	MTNR1B			ENSG00000134640	NA	NA	rs10830963-G	rs10830963	0	10830963	intron_variant	0	0.3	3e-43	42.5228787452803		0.034	[0.026-0.042] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	7p21.2	7	15024684	TMEM195, DGKB	GTF3AP5 - AC006458.1	ENSG00000225816	ENSG00000227489		38610	41523	rs2191349-T	rs2191349	0	2191349	intergenic_variant	1	0.52	3e-17	16.5228787452803		0.017	[0.011-0.023] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	7p13	7	44196069	GCK	GCK			ENSG00000106633	NA	NA	rs4607517-A	rs4607517	0	4607517	intron_variant	0	0.16	2e-16	15.698970004336		0.025	[0.015-0.035] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	11q12.2	11	61804006	FADS1	FADS2, FADS1			ENSG00000134824, ENSG00000149485	NA	NA	rs174550-T	rs174550	0	174550	5_prime_UTR_variant	0	0.64	5e-13	12.301029995664		0.02	[0.014-0.026] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	1p32.1	1	60629886	NF1A	LINC01748			ENSG00000226476	NA	NA	rs472913-C	rs472913	0	472913	intron_variant	0	0.50	2e-07	6.69897000433602		1.18	[1.11-1.25]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	8p12	8	34269430	NR	AC090993.1			ENSG00000253108	NA	NA	rs6990255-T	rs6990255	0	6990255	intron_variant	0	0.95	6e-06	5.22184874961636		1.33	[1.18-1.51]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	9q34.13	9	132969648	NR	GFI1B			ENSG00000165702	NA	NA	rs2905072-A	rs2905072	0	2905072	intron_variant	0	0.77	6e-06	5.22184874961636		1.21	[1.11-1.32]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	17q21.33	17	49486650	NR	AC091180.5 - AC015656.1	ENSG00000262039	ENSG00000279036		9662	7573	rs1035050-T	rs1035050	0	1035050	intergenic_variant	1	0.40	9e-06	5.04575749056067		1.17	[1.09-1.25]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	19p13.3	19	1811604	NR	ATP8B3			ENSG00000130270	NA	NA	rs7250872-T	rs7250872	0	7250872	missense_variant	0	0.69	2e-06	5.69897000433602		1.21	[1.12-1.31]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	2q11.2	2	98849039	intergenic	KIAA1211L			ENSG00000196872	NA	NA	rs6733011-G	rs6733011	0	6733011	intron_variant	0	0.46	3e-06	5.52287874528034		1.17	[1.10-1.25]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	3p21.1	3	52786995	ITIH1, NEK4	ITIH1			ENSG00000055957	NA	NA	rs1042779-A	rs1042779	0	1042779	missense_variant	0	0.63	2e-07	6.69897000433602		1.19	[1.11-1.27]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	3q26.1	3	164044176	NR	AC084017.1 - MIR1263	ENSG00000214210	ENSG00000221251		41711	127295	rs7427021-G	rs7427021	0	7427021	intergenic_variant	1	0.56	5e-06	5.30102999566398		1.16	[1.09-1.24]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	5q15	5	94818883	MCTP1	MCTP1			ENSG00000175471	NA	NA	rs17418283-C	rs17418283	0	17418283	intron_variant	0	0.28	1e-07	7		1.21	[1.13-1.30]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	15q23	15	70188275	NR	TLE3 - RNU6-745P	ENSG00000140332	ENSG00000200216		90099	4961	rs6494849-A	rs6494849	0	6494849	intergenic_variant	1	0.12	7e-06	5.15490195998574		1.23	[1.13-1.35]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	2p12	2	79312862	CTNNA2	CTNNA2			ENSG00000066032	NA	NA	rs13409348-G	rs13409348	0	13409348	intron_variant	0	0.24	3e-06	5.52287874528034		1.2	[1.11-1.29]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	4q12	4	54616651	KIT	LINC02260 - KIT	ENSG00000250456	ENSG00000157404		9520	41267	rs2537859-T	rs2537859	0	2537859	intergenic_variant	1	0.60	4e-06	5.39794000867204		1.16	[1.09-1.24]	Affymetrix, Illumina [2366197] (imputed)	N
2009-05-14	19416921	Scott LJ	2009-05-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19416921	Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry.	Bipolar disorder	3,683 European ancestry cases, 14,507 European ancestry controls	NA	11q13.2	11	66567837	NR	CTSF			ENSG00000174080	NA	NA	rs2242663-T	rs2242663	0	2242663	intron_variant	0	0.25	1e-06	6		1.2	[1.11-1.29]	Affymetrix, Illumina [2366197] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	9p24.2	9	4289050	GLIS3	GLIS3			ENSG00000107249	NA	NA	rs7034200-A	rs7034200	0	7034200	intron_variant	0	0.49	1e-13	13		0.02	[0.012-0.028] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	3q21.1	3	123346931	ADCY5	ADCY5			ENSG00000173175	NA	NA	rs11708067-A	rs11708067	0	11708067	intron_variant	0	0.78	3e-12	11.5228787452803		0.023	[0.015-0.031] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	10q25.2	10	111282335	ADRA2A	AL355863.1 - BTBD7P2	ENSG00000213247	ENSG00000237618		177087	40443	rs10885122-G	rs10885122	0	10885122	intergenic_variant	1	0.87	2e-06	5.69897000433602		0.01	[0.0002-0.0198] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	3q26.2	3	170999732	SLC2A2	AC061708.1, SLC2A2			ENSG00000286856, ENSG00000163581	NA	NA	rs11920090-T	rs11920090	0	11920090	intron_variant	0	0.87	5e-06	5.30102999566398		0.012	[0.0022-0.0218] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2018-01-23	20081858	Dupuis J	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Homeostasis model assessment of beta-cell function	36,466 European ancestry individuals	62,264 European ancestry individuals	1q32.3	1	213985913	PROX1	PROX1, PROX1-AS1, AC011700.1			ENSG00000117707, ENSG00000230461, ENSG00000274895	NA	NA	rs340874-C	rs340874	0	340874	non_coding_transcript_exon_variant	0	0.52	5e-06	5.30102999566398		0.008	[0.0021-0.0139] unit decrease (replication)	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	2p13.3	2	68971256	NR	GKN2 - GKN1	ENSG00000183607	ENSG00000169605		18363	3317	rs4254535-?	rs4254535	0	4254535	regulatory_region_variant	1	NR	5e-06	5.30102999566398		1.12	[NR]	Illumina [511919]	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	5p15.33	5	1315545	CLPTM1L	MIR4457 - CLPTM1L	ENSG00000263670	ENSG00000049656		6168	2207	rs4975616-?	rs4975616	0	4975616	intergenic_variant	1	NR	3e-09	8.52287874528034		1.15	[1.10-1.20]	Illumina [511919]	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	15q25.1	15	78513681	CHRNA3	HYKK			ENSG00000188266	NA	NA	rs8034191-?	rs8034191	0	8034191	intron_variant	0	NR	3e-26	25.5228787452803		1.29	[1.23-1.35]	Illumina [511919]	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	15q15.2	15	43267033	TGM5	TGM5 - ATP5PDP1	ENSG00000104055	ENSG00000261679		105	871	rs748404-?	rs748404	0	748404	TF_binding_site_variant	1	NR	1e-06	6		1.15	[1.09-1.20]	Illumina [511919]	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	6p21.33	6	31652743	BAT3	APOM, APOM, APOM, APOM, APOM, APOM, APOM			ENSG00000227567, ENSG00000226215, ENSG00000204444, ENSG00000235754, ENSG00000231974, ENSG00000224290, ENSG00000206409	NA	NA	rs3117582-?	rs3117582	0	3117582	intron_variant	0	NR	4e-10	9.39794000867204		1.24	[1.16-1.33]	Illumina [511919]	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	10q23.31	10	88967577	NR	ACTA2, STAMBPL1			ENSG00000107796, ENSG00000138134	NA	NA	rs1926203-?	rs1926203	0	1926203	intron_variant	0	NR	1e-06	6		1.12	[NR]	Illumina [511919]	N
2009-09-14	19654303	Broderick P	2009-08-04	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/19654303	Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.	Lung cancer	1,952 European ancestry cases, 1,438 European ancestry controls	2,465 European ancestry cases, 3,005 European ancestry controls, 3,143 individuals, 3,762 individuals	3p24.1	3	29533972	NR	RBMS3-AS2, RBMS3, AC098650.1			ENSG00000203506, ENSG00000144642, ENSG00000283563	NA	NA	rs1530057-?	rs1530057	0	1530057	intron_variant	0	NR	3e-06	5.52287874528034		1.26	[NR]	Illumina [511919]	N
2008-08-11	18668548	Julia A	2008-08-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18668548	Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.	Rheumatoid arthritis	400 European ancestry cases, 400 European ancestry controls	410 European ancestry cases, 394 European ancestry controls	6p21.32	6	32696074	HLA-DQA2, HLA-DQA1	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		27691	10050	rs6457617-?	rs6457617	0	6457617	intergenic_variant	1	NR	1e-09	9		NA		Illumina [299918]	N
2008-08-11	18668548	Julia A	2008-08-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18668548	Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.	Rheumatoid arthritis	400 European ancestry cases, 400 European ancestry controls	410 European ancestry cases, 394 European ancestry controls	18q23	18	78649597	SALL3	Y_RNA - AC044873.1	ENSG00000265852	ENSG00000266273		105409	146015	rs2002842-A	rs2002842	0	2002842	intergenic_variant	1	0.49	6e-06	5.22184874961636		1.61	[NR]	Illumina [299918]	N
2011-01-12	21131588	Slager SL	2010-12-03	Blood	www.ncbi.nlm.nih.gov/pubmed/21131588	Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.	Chronic lymphocytic leukemia	407 European ancestry cases, 296 European ancestry controls	252 European ancestry cases, 965 European ancestry controls	16q24.1	16	85910833	IRF8	IRF8			ENSG00000140968	NA	NA	rs391525-?	rs391525	0	391525	intron_variant	0	0.66	3e-09	8.52287874528034		1.56	[1.35-1.82]	Affymetrix [827777]	N
2011-01-12	21131588	Slager SL	2010-12-03	Blood	www.ncbi.nlm.nih.gov/pubmed/21131588	Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.	Chronic lymphocytic leukemia	407 European ancestry cases, 296 European ancestry controls	252 European ancestry cases, 965 European ancestry controls	6p21.32	6	32638979	HLA-DQA1	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs9272535-A	rs9272535	0	9272535	missense_variant	0	0.27	9e-08	7.04575749056067		1.61	[1.35-1.92]	Affymetrix [827777]	N
2011-01-12	21131588	Slager SL	2010-12-03	Blood	www.ncbi.nlm.nih.gov/pubmed/21131588	Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.	Chronic lymphocytic leukemia	407 European ancestry cases, 296 European ancestry controls	252 European ancestry cases, 965 European ancestry controls	6p21.32	6	32610305	HLA-DRB5	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		20457	17874	rs674313-T	rs674313	0	674313	intergenic_variant	1	0.26	7e-09	8.15490195998574		1.69	[1.41-2.01]	Affymetrix [827777]	N
2011-01-12	21131588	Slager SL	2010-12-03	Blood	www.ncbi.nlm.nih.gov/pubmed/21131588	Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.	Chronic lymphocytic leukemia	407 European ancestry cases, 296 European ancestry controls	252 European ancestry cases, 965 European ancestry controls	6p25.3	6	417727	NR	IRF4 - AL512308.1	ENSG00000137265	ENSG00000286364		6284	35664	rs9378805-C	rs9378805	0	9378805	intergenic_variant	1	0.49	2e-06	5.69897000433602		1.38	[1.20-1.58]	Affymetrix [827777]	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	10p15.1	10	5995763	IL2RA	IL15RA - IL2RA	ENSG00000134470	ENSG00000134460		17576	14926	rs7911500-?	rs7911500	0	7911500	intergenic_variant	1	NR	5e-09	8.30102999566398	(hsCRP-IL6 pattern prefenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	7p14.1	7	42286026	intergenic	GLI3 - LINC01448	ENSG00000106571	ENSG00000238284		48156	375690	rs12532960-?	rs12532960	0	12532960	intergenic_variant	1	NR	3e-07	6.52287874528034	(hsCRP-IL6 pattern prefenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	2p24.1	2	19799585	intergenic	AC019055.1 - CISD1P1	ENSG00000235911	ENSG00000213403		82009	26664	rs6728440-?	rs6728440	0	6728440	intergenic_variant	1	NR	2e-07	6.69897000433602	(hsCRP-IL6 pattern postfenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	4p15.33	4	13100727	intergenic	U6 - HSP90AB2P	ENSG00000277091	ENSG00000205940		49316	232687	rs13122273-?	rs13122273	0	13122273	regulatory_region_variant	1	NR	9e-07	6.04575749056067	(C-reactive protein)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	14q13.1	14	33117357	NPAS3	NPAS3			ENSG00000151322	NA	NA	rs17460823-?	rs17460823	0	17460823	intron_variant	0	NR	2e-06	5.69897000433602	(C-reactive protein)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	1p32.3	1	55595278	intergenic	AL603840.1			ENSG00000234810	NA	NA	rs10888935-?	rs10888935	0	10888935	intron_variant	0	NR	7e-07	6.15490195998574	(Interleukin-6)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	2q14.1	2	114292241	intergenic	SEPHS1P7 - RNU2-41P	ENSG00000231926	ENSG00000222923		31015	127884	rs4513299-?	rs4513299	0	4513299	intergenic_variant	1	NR	4e-06	5.39794000867204	(Interleukin-6)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	21q22.11	21	33170482	intergenic	LINC01548			ENSG00000229086	NA	NA	rs6517147-?	rs6517147	0	6517147	intron_variant	0	NR	7e-07	6.15490195998574	(Interleukin-2 soluble receptor-a)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	18q23	18	77941567	intergenic	RNA5SP461 - LINC01029	ENSG00000252260	ENSG00000265843		78000	29070	rs11661856-?	rs11661856	0	11661856	intergenic_variant	1	NR	1e-06	6	(Interleukin-2 soluble receptor-a)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	11p15.2	11	14076935	SPON1	SPON1			ENSG00000262655	NA	NA	rs17556665-?	rs17556665	0	17556665	intron_variant	0	NR	1e-06	6	(Tumor necrosis factor-a)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	7q32.1	7	129353915	AHCYL2	AHCYL2			ENSG00000158467	NA	NA	rs11979476-?	rs11979476	0	11979476	intron_variant	0	NR	2e-06	5.69897000433602	(Tumor necrosis factor-a)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	10q11.23	10	49368588	DRGX	DRGX			ENSG00000165606	NA	NA	rs12220898-?	rs12220898	0	12220898	intron_variant	0	NR	1e-06	6	(Monocyte chemoattractant protein-1)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	8q24.23	8	138243675	FAM135B	FAM135B			ENSG00000147724	NA	NA	rs4909764-?	rs4909764	0	4909764	intron_variant	0	NR	2e-06	5.69897000433602	(Monocyte chemoattractant protein-1)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	19p13.12	19	15613392	CYP4F8	AC093072.1			ENSG00000266951	NA	NA	rs3764563-?	rs3764563	0	3764563	non_coding_transcript_exon_variant	0	NR	3e-07	6.52287874528034	(MCP1-TNF-a pattern prefenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	10p12.1	10	26485765	APBB1IP	APBB1IP			ENSG00000077420	NA	NA	rs786870-?	rs786870	0	786870	intron_variant	0	NR	5e-07	6.30102999566398	(MCP1-TNF-a pattern prefenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	2p24.1	2	19758735	intergenic	AC019055.1 - CISD1P1	ENSG00000235911	ENSG00000213403		41159	67514	rs17564315-?	rs17564315	0	17564315	intergenic_variant	1	NR	7e-07	6.15490195998574	(MCP1-TNF-a pattern prefenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	5q23.1	5	116176655	COMMD10	COMMD10			ENSG00000145781	NA	NA	rs1396485-?	rs1396485	0	1396485	intron_variant	0	NR	7e-07	6.15490195998574	(MCP1-TNF-a pattern prefenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	10p15.1	10	6011200	IL2RA	IL2RA			ENSG00000134460	NA	NA	rs12722605-?	rs12722605	0	12722605	3_prime_UTR_variant	0	NR	3e-07	6.52287874528034	(MCP1-TNF-a pattern postfenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2012-03-10	22228203	Aslibekyan S	2012-01-05	Pharmacogenet Genomics	www.ncbi.nlm.nih.gov/pubmed/22228203	A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network.	Inflammatory biomarkers	1,092 European ancestry individuals	NA	11p12	11	36990987	Intergeic	AC104042.1 - AC061997.1	ENSG00000254498	ENSG00000251838		293120	711138	rs391317-?	rs391317	0	391317	intergenic_variant	1	NR	5e-07	6.30102999566398	(MCP1-TNF-a pattern postfenofibrate)	NA		Affymetrix [2543887] (imputed)	N
2010-10-07	20871597	Miki D	2010-09-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20871597	Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.	Lung adenocarcinoma	1,004 Japanese ancestry cases, 1,900 Japanese ancestry controls	1,094 East Asian ancestry cases, 9,148 East Asian ancestry controls	3q28	3	189665394	TP63	TP63			ENSG00000073282	NA	NA	rs10937405-C	rs10937405	0	10937405	intron_variant	0	0.67	7e-12	11.1549019599857		1.31	[1.22-1.42]	Illumina [432024]	N
2010-10-07	20871597	Miki D	2010-09-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20871597	Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations.	Lung adenocarcinoma	1,004 Japanese ancestry cases, 1,900 Japanese ancestry controls	1,094 East Asian ancestry cases, 9,148 East Asian ancestry controls	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-C	rs2736100	0	2736100	3_prime_UTR_variant	0	0.39	3e-11	10.5228787452803		1.27	[1.19-1.37]	Illumina [432024]	N
2010-07-01	20529992	Teupser D	2010-06-07	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20529992	Genetic regulation of serum phytosterol levels and risk of coronary artery disease.	Phytosterol levels	1,495 European ancestry individuals	2,917 European ancestry individuals	2p21	2	43846517	ABCG8	ABCG8			ENSG00000143921	NA	NA	rs41360247-C	rs41360247	0	41360247	non_coding_transcript_exon_variant	0	0.064	6e-25	24.2218487496164	(campesterol)	14	[NR] % decrease	Affymetrix [374370]	N
2010-07-01	20529992	Teupser D	2010-06-07	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20529992	Genetic regulation of serum phytosterol levels and risk of coronary artery disease.	Phytosterol levels	1,495 European ancestry individuals	2,917 European ancestry individuals	2p21	2	43847292	ABCG8	ABCG8			ENSG00000143921	NA	NA	rs4245791-C	rs4245791	0	4245791	non_coding_transcript_exon_variant	0	0.322	2e-50	49.698970004336	(campesterol)	12	[NR] % increase	Affymetrix [374370]	N
2010-07-01	20529992	Teupser D	2010-06-07	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20529992	Genetic regulation of serum phytosterol levels and risk of coronary artery disease.	Phytosterol levels	1,495 European ancestry individuals	2,917 European ancestry individuals	9q34.2	9	133263862	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs657152-T	rs657152	0	657152	intron_variant	0	0.383	9e-13	12.0457574905607	(campesterol)	8	[NR] % increase	Affymetrix [374370]	N
2009-03-30	19300499	Takeuchi F	2009-03-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19300499	A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.	Warfarin maintenance dose	1,053 European ancestry individuals	588 European ancestry individuals	16p11.2	16	31096368	VKORC1	VKORC1 - BCKDK	ENSG00000167397	ENSG00000103507		388	9739	rs9923231-T	rs9923231	0	9923231	regulatory_region_variant	1	0.40	3e-181	180.52287874528		0.97	[0.91-1.02] mg/week decrease	Illumina [325997]	N
2009-03-30	19300499	Takeuchi F	2009-03-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19300499	A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.	Warfarin maintenance dose	1,053 European ancestry individuals	588 European ancestry individuals	10q23.33	10	94942290	CYP2C9	CYP2C9			ENSG00000138109	NA	NA	rs1799853-?	rs1799853	0	1799853	missense_variant	0	0.11	1e-31	31		0.54	[0.45-0.63] mg/week decrease	Illumina [325997]	N
2009-03-30	19300499	Takeuchi F	2009-03-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19300499	A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.	Warfarin maintenance dose	1,053 European ancestry individuals	588 European ancestry individuals	19p13.12	19	15879621	CYP4F2	CYP4F2			ENSG00000186115	NA	NA	rs2108622-?	rs2108622	0	2108622	missense_variant	0	0.24	3e-10	9.52287874528034		0.21	[0.14-0.27] mg/week increase	Illumina [325997]	N
2009-03-30	19300499	Takeuchi F	2009-03-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19300499	A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.	Warfarin maintenance dose	1,053 European ancestry individuals	588 European ancestry individuals	10q23.33	10	94981296	CYP2C9	CYP2C9			ENSG00000138109	NA	NA	rs1057910-?	rs1057910	0	1057910	missense_variant	0	0.07	3e-79	78.5228787452803		1.11	[1.00-1.22] mg/week decrease	Illumina [325997]	N
2013-03-26	23321320	Urabe Y	2013-01-12	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/23321320	A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.	Hepatitis C induced liver cirrhosis	682 Japanese ancestry cases, 1,045 Japanese ancestry controls	936 Japanese ancestry cases, 3,809 Japanese ancestry controls	6p21.32	6	32347950	C6orf10	TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1-AS1			ENSG00000234280, ENSG00000232106, ENSG00000206245, ENSG00000204296, ENSG00000206310, ENSG00000226892, ENSG00000237881, ENSG00000236672, ENSG00000225914	NA	NA	rs910049-A	rs910049	0	910049	intron_variant	0	0.142	9e-11	10.0457574905607		1.46	[1.28-1.62]	Illumina [431618]	N
2013-03-26	23321320	Urabe Y	2013-01-12	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/23321320	A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.	Hepatitis C induced liver cirrhosis	682 Japanese ancestry cases, 1,045 Japanese ancestry controls	936 Japanese ancestry cases, 3,809 Japanese ancestry controls	6p21.32	6	32400310	BTNL2	BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, TSBP1-AS1			ENSG00000226127, ENSG00000225412, ENSG00000204290, ENSG00000225845, ENSG00000229741, ENSG00000224770, ENSG00000229597, ENSG00000224242, ENSG00000225914	NA	NA	rs3817963-A	rs3817963	0	3817963	intron_variant	0	0.315	1e-08	8		1.3	[1.18-1.42]	Illumina [431618]	N
2013-03-26	23321320	Urabe Y	2013-01-12	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/23321320	A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.	Hepatitis C induced liver cirrhosis	682 Japanese ancestry cases, 1,045 Japanese ancestry controls	936 Japanese ancestry cases, 3,809 Japanese ancestry controls	6p21.32	6	32411959	intergenic	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794		4196	27919	rs9405098-A	rs9405098	0	9405098	intergenic_variant	1	0.253	1e-10	10		1.37	[1.24-1.51]	Illumina [431618]	N
2013-03-26	23321320	Urabe Y	2013-01-12	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/23321320	A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.	Hepatitis C induced liver cirrhosis	682 Japanese ancestry cases, 1,045 Japanese ancestry controls	936 Japanese ancestry cases, 3,809 Japanese ancestry controls	6p21.32	6	32421871	intergenic	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794		14108	18007	rs3135363-C	rs3135363	0	3135363	intergenic_variant	1	0.702	1e-10	10		1.37	[1.24-1.51]	Illumina [431618]	N
2013-03-26	23321320	Urabe Y	2013-01-12	J Hepatol	www.ncbi.nlm.nih.gov/pubmed/23321320	A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region.	Hepatitis C induced liver cirrhosis	682 Japanese ancestry cases, 1,045 Japanese ancestry controls	936 Japanese ancestry cases, 3,809 Japanese ancestry controls	6p21.32	6	32433302	intergenic	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794		25539	6576	rs3129860-A	rs3129860	0	3129860	intergenic_variant	1	0.231	1e-09	9		1.36	[1.22-1.49]	Illumina [431618]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	9q34.3	9	135137855	OLFM1	OLFM1 - AL390778.1	ENSG00000130558	ENSG00000227958		16676	66867	rs10776934-T	rs10776934	0	10776934	regulatory_region_variant	1	NR	1e-06	6		0.281	[0.17-0.39] ug/L decrease	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	2q36.1	2	223594965	SCG2	AC013448.2 - SCG2	ENSG00000235610	ENSG00000171951		84032	1975	rs16864968-G	rs16864968	0	16864968	intergenic_variant	1	NR	3e-06	5.52287874528034		0.826	[0.48-1.17] ug/L decrease	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	4p11	4	49060875	CWH43	CWH43			ENSG00000109182	NA	NA	rs11725957-G	rs11725957	0	11725957	intron_variant	0	NR	8e-06	5.09691001300806		0.727	[0.41-1.05] ug/L increase	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	6q25.3	6	160402996	SLC22A3	SLC22A3			ENSG00000146477	NA	NA	rs2504916-T	rs2504916	0	2504916	intron_variant	0	NR	2e-06	5.69897000433602		0.306	[0.18-0.43] ug/L increase	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	6p25.3	6	1535763	RP11-157J24.1	AL512329.2 - FOXCUT	ENSG00000272279	ENSG00000280916		6852	65891	rs11242704-G	rs11242704	0	11242704	regulatory_region_variant	1	NR	5e-06	5.30102999566398		0.257	[0.15-0.37] ug/L decrease	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	6q16.1	6	93201401	EPHA7	AL138731.1 - EPHA7	ENSG00000235099	ENSG00000135333		98017	38619	rs12527818-T	rs12527818	0	12527818	intergenic_variant	1	NR	7e-06	5.15490195998574		0.274	[0.15-0.39] ug/L increase	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	1p33	1	46713638	KIAA0494	EFCAB14			ENSG00000159658	NA	NA	rs10789491-G	rs10789491	0	10789491	intron_variant	0	NR	1e-06	6		0.312	[0.19-0.44] ug/L increase	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	1p36.13	1	17508246	ARHGEF10L	RCC2 - ARHGEF10L	ENSG00000281540	ENSG00000074964		68569	31452	rs2254135-T	rs2254135	0	2254135	regulatory_region_variant	1	NR	3e-06	5.52287874528034		0.269	[0.16-0.38] ug/L increase	NR [NR]	N
2011-12-20	22095909	Lange CM	2011-11-16	Hepatology	www.ncbi.nlm.nih.gov/pubmed/22095909	Serum ferritin levels are associated with a distinct phenotype of chronic hepatitis C poorly responding to pegylated interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	707 European ancestry cases	NA	1p31.1	1	84399547	DNASE2B	DNASE2B			ENSG00000137976	NA	NA	rs12144715-T	rs12144715	0	12144715	intron_variant	0	NR	7e-06	5.15490195998574		0.636	[0.36-0.91] ug/L decrease	NR [NR]	N
2011-12-24	22144915	Fan Q	2011-12-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22144915	Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.	Corneal astigmatism	1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls	825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios	2q33.1	2	198814386	intergenic	AC019330.1 - AC020718.1	ENSG00000225421	ENSG00000231557		42030	68187	rs10189905-?	rs10189905	0	10189905	intergenic_variant	1	NR	6e-07	6.22184874961636		1.32	[1.18-1.46]	Illumina [460528]	N
2011-12-24	22144915	Fan Q	2011-12-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22144915	Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.	Corneal astigmatism	1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls	825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios	2q36.3	2	226136270	intergenic	AC068138.1 - AC062015.1	ENSG00000230621	ENSG00000235070		143073	43774	rs6758183-A	rs6758183	0	6758183	intergenic_variant	1	NR	3e-06	5.52287874528034		1.39	[1.21-1.57]	Illumina [460528]	N
2011-12-24	22144915	Fan Q	2011-12-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22144915	Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.	Corneal astigmatism	1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls	825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios	4q12	4	54221414	intergenic	AC058822.1, RPL22P13			ENSG00000282278, ENSG00000242670	NA	NA	rs17084051-A	rs17084051	0	17084051	non_coding_transcript_exon_variant	0	0.23	2e-06	5.69897000433602		1.21	[1.13-1.29]	Illumina [460528]	N
2011-12-24	22144915	Fan Q	2011-12-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22144915	Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.	Corneal astigmatism	1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls	825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios	4q12	4	54258293	PDGFRA	AC058822.1, PDGFRA			ENSG00000282278, ENSG00000134853	NA	NA	rs7677751-T	rs7677751	0	7677751	intron_variant	0	0.22	8e-09	8.09691001300806		1.26	[1.18-1.34]	Illumina [460528]	N
2011-12-24	22144915	Fan Q	2011-12-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22144915	Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.	Corneal astigmatism	1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls	825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios	3p14.1	3	67480964	SUCLG2	SUCLG2			ENSG00000172340	NA	NA	rs6792584-G	rs6792584	0	6792584	intron_variant	0	NR	5e-06	5.30102999566398		1.24	[1.14-1.34]	Illumina [460528]	N
2011-12-24	22144915	Fan Q	2011-12-01	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22144915	Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism.	Corneal astigmatism	1,231 Chinese ancestry cases, 785 Chinese ancestry controls, 1,018 Malay ancestry cases, 1,220 Malay ancestry controls	825 Indian ancestry cases, 1,314 Indian ancestry controls, 760 Chinese ancestry child cases, 169 Chinese ancestry child controls, 397 Chinese ancestry trios	11q13.4	11	74457366	KCNE3	AP001372.1, KCNE3			ENSG00000254631, ENSG00000175538	NA	NA	rs2270676-G	rs2270676	0	2270676	synonymous_variant	0	NR	5e-06	5.30102999566398		1.29	[1.17-1.41]	Illumina [460528]	N
2011-05-26	21502949	Stein JL	2011-04-19	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21502949	Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.	Caudate nucleus volume	734 European ancestry individuals	464 European ancestry individuals	6p25.3	6	2235399	GMDS	GMDS			ENSG00000112699	NA	NA	rs9378688-A	rs9378688	0	9378688	intron_variant	0	0.12	6e-06	5.22184874961636	(Left caudate)	154.2	[87.56-220.84] mm3 decrease	Illumina [520459]	N
2011-05-26	21502949	Stein JL	2011-04-19	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21502949	Discovery and replication of dopamine-related gene effects on caudate volume in young and elderly populations (N=1198) using genome-wide search.	Caudate nucleus volume	734 European ancestry individuals	464 European ancestry individuals	5q13.3	5	77485646	PDE8B, WDR41	WDR41			ENSG00000164253	NA	NA	rs163030-A	rs163030	0	163030	intron_variant	0	0.50	2e-07	6.69897000433602	(Right caudate)	117.5	[73.01-161.99] mm3 increase	Illumina [520459]	N
2010-02-28	20112360	Kerkhof HJ	2010-01-07	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/20112360	A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.	Osteoarthritis	1,341 European ancestry cases, 3,496 European ancestry controls	9,779 European ancestry cases, up to 31,818 European ancestry controls, 3,818 cases, 7,278 controls	7q22.3	7	107297975	COG5	COG5, COG5			ENSG00000164597, ENSG00000284369	NA	NA	rs3815148-C	rs3815148	0	3815148	intron_variant	0	0.23	8e-08	7.09691001300806		1.14	[1.09-1.19]	Illumina [500510]	N
2008-11-12	18835860	Mushiroda T	2008-10-01	J Med Genet	www.ncbi.nlm.nih.gov/pubmed/18835860	A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis.	Idiopathic pulmonary fibrosis	159 Japanese ancestry cases, 934 Japanese ancestry controls	83 Japanese ancestry cases, 535 Japanese ancestry controls	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-A	rs2736100	0	2736100	3_prime_UTR_variant	0	0.41	3e-08	7.52287874528034		2.11	[1.61-2.78]	Illumina [214508]	N
2009-05-28	19448620	Perry JR	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448620	Meta-analysis of genome-wide association data identifies two loci influencing age at menarche.	Menarche (age at onset)	17,510 European ancestry female individuals	NA	9q31.2	9	106204807	ZNF462, SLC44A1, FKTN, TAL2, FSD1L, TMEM38B	LINC01505			ENSG00000234323	NA	NA	rs2090409-A	rs2090409	0	2090409	intron_variant	0	0.31	2e-09	8.69897000433602		0.1	[0.06-0.14] years decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-05-28	19448620	Perry JR	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448620	Meta-analysis of genome-wide association data identifies two loci influencing age at menarche.	Menarche (age at onset)	17,510 European ancestry female individuals	NA	6q16.3	6	104931079	LIN28B	LIN28B-AS1			ENSG00000203809	NA	NA	rs7759938-C	rs7759938	0	7759938	intron_variant	0	0.33	7e-09	8.15490195998574		0.09	[0.05-0.13] years increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	12q24.13	12	112049014	C12orf30	NAA25			ENSG00000111300	NA	NA	rs17696736-G	rs17696736	0	17696736	intron_variant	0	0.42	2e-16	15.698970004336		1.22	[1.15-1.28]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	18q22.2	18	69864406	CD226	CD226			ENSG00000150637	NA	NA	rs763361-A	rs763361	0	763361	missense_variant	0	0.47	1e-08	8		1.16	[1.10-1.22]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	5p13.2	5	35910427	CAPSL	CAPSL			ENSG00000152611	NA	NA	rs1445898-G	rs1445898	0	1445898	missense_variant	0	0.55	8e-06	5.09691001300806		1.12	[1.06-1.19]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	12q13.2	12	56088396	ERBB3	ERBB3			ENSG00000065361	NA	NA	rs2292239-A	rs2292239	0	2292239	intron_variant	0	0.34	2e-20	19.698970004336		1.28	[1.21-1.35]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	16p13.13	16	11086016	KIAA0350	CLEC16A			ENSG00000038532	NA	NA	rs12708716-A	rs12708716	0	12708716	intron_variant	0	0.68	3e-18	17.5228787452803		1.23	[1.16-1.30]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	18p11.21	18	12779948	PTPN2	AP005482.1 - PTPN2	ENSG00000260302	ENSG00000175354		3808	5530	rs2542151-C	rs2542151	0	2542151	intergenic_variant	1	0.16	1e-14	14		1.3	[1.22-1.40]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	1p13.2	1	113834946	PTPN22	PTPN22, AL137856.1			ENSG00000134242, ENSG00000231128	NA	NA	rs2476601-T	rs2476601	0	2476601	missense_variant	0	0.09	2e-80	79.698970004336		1.98	[1.82-2.15]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	5p13.2	5	35874473	IL7R	IL7R			ENSG00000168685	NA	NA	rs6897932-G	rs6897932	0	6897932	missense_variant	0	0.71	8e-06	5.09691001300806		1.12	[1.06-1.19]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	2q11.2	2	100208905	AFF3, LOC150577	LINC01104			ENSG00000232084	NA	NA	rs9653442-G	rs9653442	0	9653442	intron_variant	0	0.46	5e-06	5.30102999566398		1.11	[1.05-1.17]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	1p13.2	1	113761186	PHTF1, PTPN22	PHTF1 - RSBN1	ENSG00000116793	ENSG00000081019		1697	646	rs6679677-A	rs6679677	0	6679677	intergenic_variant	1	0.10	8e-24	23.0969100130081		1.89	[1.67-2.13]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	11p15.5	11	2148544	INS	INS-IGF2, AC132217.2, IGF2-AS			ENSG00000129965, ENSG00000284779, ENSG00000099869	NA	NA	rs3741208-T	rs3741208	0	3741208	non_coding_transcript_exon_variant	0	0.38	2e-07	6.69897000433602		1.25	[1.15-1.35]	Affymetrix [NR]	N
2008-06-16	17554260	Todd JA	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554260	Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.	Type 1 diabetes	2,000 European ancestry cases, 3,000 European ancestry controls	2,997 European ancestry trios, 4,000 European ancestry cases, 5,000 European ancestry controls	2q24.2	2	162267541	IFIH1	IFIH1			ENSG00000115267	NA	NA	rs1990760-A	rs1990760	0	1990760	missense_variant	0	0.60	2e-11	10.698970004336		1.18	[1.11-1.23]	Affymetrix [NR]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	16q12.2	16	53782363	FTO	FTO			ENSG00000140718	NA	NA	rs8050136-A	rs8050136	0	8050136	intron_variant	0	0.40	7e-14	13.1549019599857		1.23	[1.18-1.32]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	3q27.2	3	185793899	IGF2BP2	IGF2BP2			ENSG00000073792	NA	NA	rs4402960-T	rs4402960	0	4402960	intron_variant	0	0.32	9e-16	15.0457574905607	(DGI+FUSION+WTCCC)	1.14	[1.11-1.18]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	8q24.11	8	117172544	SLC30A8	SLC30A8			ENSG00000164756	NA	NA	rs13266634-C	rs13266634	0	13266634	missense_variant	0	0.69	5e-08	7.30102999566398	(DGI+FUSION+WTCCC)	1.12	[1.07-1.16]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	6p22.3	6	20660803	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs10946398-C	rs10946398	0	10946398	intron_variant	0	0.32	1e-08	8		1.16	[1.10-1.22]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	10q23.33	10	92705802	HHEX	HHEX - Y_RNA	ENSG00000152804	ENSG00000265852		10155	4697	rs5015480-C	rs5015480	0	5015480	intergenic_variant	1	0.57	5e-06	5.30102999566398		1.13	[1.07-1.19]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	10q25.2	10	112994329	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7901695-C	rs7901695	0	7901695	intron_variant	0	NR	1e-48	48	(DGI+FUSION+WTCCC)	1.37	[1.31-1.43]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	9p21.3	9	22029548	CDKN2A, CDKN2B	AL359922.1, CDKN2B-AS1			ENSG00000264545, ENSG00000240498	NA	NA	rs564398-T	rs564398	0	564398	3_prime_UTR_variant	0	0.56	1e-06	6		1.13	[1.08-1.19]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	11p15.1	11	17387083	KCNJ11	KCNJ11			ENSG00000187486	NA	NA	rs5215-C	rs5215	0	5215	missense_variant	0	NR	5e-11	10.301029995664	(DGI+FUSION+WTCCC)	1.14	[1.10-1.19]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	3p25.2	3	12351626	PPARG	PPARG			ENSG00000132170	NA	NA	rs1801282-C	rs1801282	0	1801282	missense_variant	0	NR	2e-06	5.69897000433602	(DGI+FUSION+WTCCC)	1.14	[1.08-1.20]	Affymetrix [393453]	N
2008-06-16	17463249	Zeggini E	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463249	Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	3,757 European ancestry cases, 5,346 European ancestry controls	9p21.3	9	22134095	CDKN2A, CDKN2B	CDKN2B-AS1 - AL157937.1	ENSG00000240498	ENSG00000236921		5992	69895	rs10811661-T	rs10811661	0	10811661	intergenic_variant	1	0.83	5e-06	5.30102999566398		1.19	[1.11-1.28]	Affymetrix [393453]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	10q24.2	10	99528007	NKX2-3	AL513542.1, LINC01475			ENSG00000228778, ENSG00000257582	NA	NA	rs10883365-?	rs10883365	0	10883365	non_coding_transcript_exon_variant	0	0.48	4e-10	9.39794000867204		1.18	[1.05-1.32]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	18p11.21	18	12779948	PTPN2	AP005482.1 - PTPN2	ENSG00000260302	ENSG00000175354		3808	5530	rs2542151-?	rs2542151	0	2542151	intergenic_variant	1	0.18	3e-08	7.52287874528034		1.15	[1.00-1.32]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	5p13.1	5	40437846	intergenic	AC093277.1 - AC114977.1	ENSG00000283286	ENSG00000285552		6355	25716	rs9292777-?	rs9292777	0	9292777	regulatory_region_variant	1	0.40	3e-18	17.5228787452803		1.34	[1.20-1.50]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	5q33.3	5	159395637	IL12B	AC008691.1			ENSG00000249738	NA	NA	rs6887695-?	rs6887695	0	6887695	intron_variant	0	0.32	9e-06	5.04575749056067		1.26	[1.12-1.41]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	5q33.1	5	150843825	IRGM	SMIM3 - IRGM	ENSG00000256235	ENSG00000237693		47091	2698	rs13361189-?	rs13361189	0	13361189	intergenic_variant	1	0.08	2e-10	9.69897000433602		1.38	[1.15-1.66]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	1q24.3	1	172929237	intergenic	AL031599.1			ENSG00000224228	NA	NA	rs12035082-?	rs12035082	0	12035082	intron_variant	0	0.40	2e-07	6.69897000433602		1.14	[1.02-1.27]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	21q22.2	21	38919816	intergenic	AP001042.1			ENSG00000205622	NA	NA	rs2836754-?	rs2836754	0	2836754	intron_variant	0	0.35	5e-07	6.30102999566398		1.15	[1.03-1.28]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	1q31.2	1	191590226	intergenic	LINC01680 - LINC02770	ENSG00000233882	ENSG00000228215		361759	233206	rs10801047-?	rs10801047	0	10801047	intergenic_variant	1	0.08	3e-08	7.52287874528034		1.47	[1.22-1.76]	Affymetrix [see WTCCC]	N
2008-06-16	17554261	Parkes M	2007-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17554261	Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.	Crohn's disease	1,748 cases, 2,938 controls	1,182 European ancestry cases, 2,024 European ancestry controls	3p21.31	3	49664550	MST1	BSN			ENSG00000164061	NA	NA	rs9858542-?	rs9858542	0	9858542	synonymous_variant	0	0.29	5e-08	7.30102999566398		1.17	[1.14-1.31]	Affymetrix [see WTCCC]	N
2009-12-29	20031579	Tarasov KV	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031579	COL4A1 is associated with arterial stiffness by genome-wide association scan.	Arterial stiffness	4,221 Sardinian individuals	1,828 Sardinian individuals, 813 Old Order Amish individuals	13q34	13	110166251	COL4A1	COL4A1			ENSG00000187498	NA	NA	rs3742207-C	rs3742207	0	3742207	missense_variant	0	0.44	5e-08	7.30102999566398		21	[11.79-30.21] cm/s increase	Affymetrix [362129] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	20p13	20	4699605	PRNP	PRNP			ENSG00000171867	NA	NA	rs1799990-?	rs1799990	0	1799990	missense_variant	0	NR	7e-07	6.15490195998574		1.3	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	3q23	3	141359346	ZBTB38, RASA2	AC117383.1, PXYLP1, ZBTB38			ENSG00000249417, ENSG00000155893, ENSG00000177311	NA	NA	rs9857275-?	rs9857275	0	9857275	intron_variant	0	NR	2e-06	5.69897000433602		1.28	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	7q21.11	7	84281955	SEMA3A	SEMA3A			ENSG00000075213	NA	NA	rs488333-?	rs488333	0	488333	intron_variant	0	NR	3e-06	5.52287874528034		1.2681	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	10q25.1	10	107810092	NR	LINC01435			ENSG00000229981	NA	NA	rs12570947-?	rs12570947	0	12570947	intron_variant	0	NR	4e-06	5.39794000867204		1.45	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	4q21.1	4	75407765	NR	AC096759.2, AC096759.1			ENSG00000250735, ENSG00000248646	NA	NA	rs2903698-?	rs2903698	0	2903698	intron_variant	0	NR	6e-06	5.22184874961636		1.2528	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	10q22.1	10	70767761	NR	ADAMTS14 - TBATA	ENSG00000138316	ENSG00000166220		5320	3478	rs12761224-?	rs12761224	0	12761224	intergenic_variant	1	NR	6e-06	5.22184874961636		1.3861	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	3p21.31	3	48445644	NR	AC134772.1			ENSG00000244380	NA	NA	rs730566-?	rs730566	0	730566	intron_variant	0	NR	7e-06	5.15490195998574		1.27	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	8p23.1	8	8864868	NR	MFHAS1, MFHAS1			ENSG00000285022, ENSG00000147324	NA	NA	rs10108954-?	rs10108954	0	10108954	intron_variant	0	NR	7e-06	5.15490195998574		1.7359	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	19q13.2	19	41167943	NR	CYP2T3P - RPL36P16	ENSG00000268529	ENSG00000224476		30635	1918	rs8105815-?	rs8105815	0	8105815	regulatory_region_variant	1	NR	8e-06	5.09691001300806		1.3918	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	8q22.2	8	98117279	NR	RIDA - POP1	ENSG00000132541	ENSG00000104356		108	14	rs2071598-?	rs2071598	0	2071598	regulatory_region_variant	1	NR	9e-06	5.04575749056067		1.2646	[NR]	Illumina [NR] (imputed)	N
2012-01-20	22210626	Mead S	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22210626	Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.	Prion diseases	1,281 European ancestry cases, 6,015 European ancestry controls, 290 Papua New Guinean ancestry cases, 286 Papua New Guinean ancestry controls	NA	5q35.2	5	173932328	NR	CPEB4			ENSG00000113742	NA	NA	rs17763373-?	rs17763373	0	17763373	intron_variant	0	NR	7e-06	5.15490195998574		1.5106	[NR]	Illumina [NR] (imputed)	N
2009-04-03	18711367	Yasuda K	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711367	Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.	Type 2 diabetes	187 Japanese ancestry cases, 1,504 Japanese ancestry controls	6,552 East Asian ancestry cases, 6,621 East Asian ancestry controls, 2,830 European ancestry cases, 3,740 European ancestry controls	11p15.4	11	2818521	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs2237892-C	rs2237892	0	2237892	intron_variant	0	0.61	2e-42	41.698970004336		1.45	[1.34-1.47]	NR [82343]	N
2009-09-24	19714249	Liu YZ	2009-08-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19714249	Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males.	Obesity and osteoporosis	499 European ancestry male individuals, 501 European ancestry female individuals	1,370 European ancestry male individuals and 1,985 European ancestry female individuals from 975 families	11p15.2	11	16381965	SOX6	SOX6			ENSG00000110693	NA	NA	rs4756846-C	rs4756846	0	4756846	intron_variant	0	0.12	5e-07	6.30102999566398	(BMI-BMD, males)	NA		Affymetrix [379319]	N
2009-09-24	19714249	Liu YZ	2009-08-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19714249	Powerful bivariate genome-wide association analyses suggest the SOX6 gene influencing both obesity and osteoporosis phenotypes in males.	Obesity and osteoporosis	499 European ancestry male individuals, 501 European ancestry female individuals	1,370 European ancestry male individuals and 1,985 European ancestry female individuals from 975 families	11p15.2	11	16368048	SOX6	SOX6			ENSG00000110693	NA	NA	rs297325-C	rs297325	0	297325	intron_variant	0	0.23	4e-07	6.39794000867204	(BMI-BMD, males)	NA		Affymetrix [379319]	N
2008-06-16	17632509	Buch S	2007-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17632509	A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.	Gallstone disease	280 European ancestry cases, 360 European ancestry controls	1,833 European ancestry cases, 1,035 European ancestry controls, 167 Hispanic cases, 167 Hispanic controls	2p21	2	43839108	ABCG8	ABCG8			ENSG00000143921	NA	NA	rs11887534-C	rs11887534	0	11887534	missense_variant	0	0.10	1e-14	14		2.2	[1.80-2.60]	Affymetrix [382492]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	6p22.3	6	20657333	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs4712523-G	rs4712523	0	4712523	intron_variant	0	0.41	7e-20	19.1549019599857		1.27	[1.21-1.33]	Illumina [482625]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	9p21.3	9	22132077	CDKN2A, CDKN2B	CDKN2B-AS1 - AL157937.1	ENSG00000240498	ENSG00000236921		3974	71913	rs2383208-A	rs2383208	0	2383208	intergenic_variant	1	0.55	2e-29	28.698970004336		1.34	[1.27-1.41]	Illumina [482625]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	11p15.4	11	2818521	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs2237892-C	rs2237892	0	2237892	intron_variant	0	0.59	1e-26	26		1.33	[1.27-1.41]	Illumina [482625]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	8q24.11	8	117172544	SLC30A8	SLC30A8			ENSG00000164756	NA	NA	rs13266634-C	rs13266634	0	13266634	missense_variant	0	0.57	2e-14	13.698970004336		1.22	[1.16-1.28]	Illumina [482625]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	10q23.33	10	92703125	HHEX	HHEX - Y_RNA	ENSG00000152804	ENSG00000265852		7478	7374	rs1111875-C	rs1111875	0	1111875	intergenic_variant	1	0.28	7e-12	11.1549019599857		1.21	[1.15-1.28]	Illumina [482625]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	0	0.04	8e-12	11.0969100130081		1.54	[1.36-1.74]	Illumina [482625]	N
2009-05-07	19401414	Takeuchi F	2009-04-29	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19401414	Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.	Type 2 diabetes	519 Japanese ancestry cases, 503 Japanese ancestry controls	5,110 Japanese ancestry cases, 6,867 Japanese ancestry controls	3q27.2	3	185793899	IGF2BP2	IGF2BP2			ENSG00000073792	NA	NA	rs4402960-T	rs4402960	0	4402960	intron_variant	0	0.31	1e-06	6		1.14	[1.08-1.21]	Illumina [482625]	N
2010-03-24	20228798	Franke A	2010-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20228798	Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).	Ulcerative colitis	1,043 European ancestry cases, 1,703 European ancestry controls	2,539 European ancestry cases, 5,428 European ancestry controls	1p36.13	1	19901230	OTUD3	OTUD3			ENSG00000169914	NA	NA	rs4654925-G	rs4654925	0	4654925	intron_variant	0	0.52	9e-22	21.0457574905607		1.41	[1.30-1.54]	Affymetrix [1897764] (imputed)	N
2010-03-24	20228798	Franke A	2010-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20228798	Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).	Ulcerative colitis	1,043 European ancestry cases, 1,703 European ancestry controls	2,539 European ancestry cases, 5,428 European ancestry controls	7q22.1	7	99162881	SMURF1, KPNA7	SMURF1 - KPNA7	ENSG00000198742	ENSG00000185467		18781	10693	rs7809799-G	rs7809799	0	7809799	regulatory_region_variant	1	0.04	9e-11	10.0457574905607		1.56	[1.36-1.78]	Affymetrix [1897764] (imputed)	N
2010-03-24	20228798	Franke A	2010-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20228798	Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).	Ulcerative colitis	1,043 European ancestry cases, 1,703 European ancestry controls	2,539 European ancestry cases, 5,428 European ancestry controls	22q13.33	22	49997051	IL17REL	IL17REL			ENSG00000188263	NA	NA	rs5771069-G	rs5771069	0	5771069	missense_variant	0	0.49	4e-08	7.39794000867204		1.17	[1.11-1.25]	Affymetrix [1897764] (imputed)	N
2010-03-24	20228798	Franke A	2010-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20228798	Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).	Ulcerative colitis	1,043 European ancestry cases, 1,703 European ancestry controls	2,539 European ancestry cases, 5,428 European ancestry controls	6p21.32	6	32465058	HLA-DRA	HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9			ENSG00000234164, ENSG00000232705, ENSG00000228260, ENSG00000227526, ENSG00000196301, ENSG00000227384, ENSG00000237591, ENSG00000226035	NA	NA	rs9268923-C	rs9268923	0	9268923	intron_variant	0	0.67	4e-15	14.397940008672		1.45	[1.33-1.59]	Affymetrix [1897764] (imputed)	N
2010-03-24	20228798	Franke A	2010-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20228798	Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).	Ulcerative colitis	1,043 European ancestry cases, 1,703 European ancestry controls	2,539 European ancestry cases, 5,428 European ancestry controls	10q24.2	10	99530544	NKX2-3	LINC01475			ENSG00000257582	NA	NA	rs6584283-T	rs6584283	0	6584283	intron_variant	0	0.46	2e-06	5.69897000433602		1.22	[1.12-1.32]	Affymetrix [1897764] (imputed)	N
2010-03-24	20228798	Franke A	2010-03-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20228798	Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).	Ulcerative colitis	1,043 European ancestry cases, 1,703 European ancestry controls	2,539 European ancestry cases, 5,428 European ancestry controls	1q32.1	1	206770623	IL10	IL10			ENSG00000136634	NA	NA	rs3024493-T	rs3024493	0	3024493	intron_variant	0	0.16	1e-12	12		1.35	[1.22-1.50]	Affymetrix [1897764] (imputed)	N
2008-06-16	17637780	Winkelmann J	2007-07-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17637780	Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.	Restless legs syndrome	401 European ancestry cases, 1,644 European ancestry controls	906 European ancestry cases, 891 European ancestry controls, 255 French Canadian cases, 287 French Canadian controls	2p14	2	66554321	MEIS1	MEIS1			ENSG00000143995	NA	NA	rs2300478-G	rs2300478	0	2300478	intron_variant	0	0.24	3e-28	27.5228787452803		1.74	[1.57-1.92]	Affymetrix [236758]	N
2008-06-16	17637780	Winkelmann J	2007-07-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17637780	Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.	Restless legs syndrome	401 European ancestry cases, 1,644 European ancestry controls	906 European ancestry cases, 891 European ancestry controls, 255 French Canadian cases, 287 French Canadian controls	6p21.2	6	38398065	BTBD9	BTBD9			ENSG00000183826	NA	NA	rs9296249-T	rs9296249	0	9296249	intron_variant	0	0.76	4e-18	17.397940008672		1.67	[1.49-1.89]	Affymetrix [236758]	N
2008-06-16	17637780	Winkelmann J	2007-07-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17637780	Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions.	Restless legs syndrome	401 European ancestry cases, 1,644 European ancestry controls	906 European ancestry cases, 891 European ancestry controls, 255 French Canadian cases, 287 French Canadian controls	15q23	15	67744514	MAP2K5, LBXCOR1	MAP2K5			ENSG00000137764	NA	NA	rs12593813-G	rs12593813	0	12593813	intron_variant	0	0.67	1e-15	15		1.5	[1.36-1.66]	Affymetrix [236758]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	5q32	5	149831285	PPARGC1B	PPARGC1B			ENSG00000155846	NA	NA	rs32579-A	rs32579	0	32579	intron_variant	0	NR	4e-06	5.39794000867204		0.11	[0.07-0.15] tanning ability score decrease	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	12q13.13	12	53765493	LOC440100	AC076968.2			ENSG00000286069	NA	NA	rs7969151-A	rs7969151	0	7969151	intron_variant	0	0.21	2e-06	5.69897000433602		0.13	[0.07-0.19] tanning ability score increase	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	16q24.3	16	90018153	MC1R	DBNDD1			ENSG00000003249	NA	NA	rs11648785-T	rs11648785	0	11648785	intron_variant	0	NR	3e-09	8.52287874528034		0.14	[0.10-0.18] tanning ability score decrease	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	6p25.3	6	475489	EXOC2	AL512308.1			ENSG00000286364	NA	NA	rs12210050-T	rs12210050	0	12210050	non_coding_transcript_exon_variant	0	NR	5e-14	13.301029995664		0.22	[0.16-0.28] tanning ability score increase	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	11q14.3	11	88824823	GRM5	GRM5			ENSG00000168959	NA	NA	rs10831496-G	rs10831496	0	10831496	intron_variant	0	NR	5e-09	8.30102999566398		0.14	[0.10-0.18] tanning ability score decrease	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	5p13.2	5	33955568	MATP	SLC45A2, SLC45A2			ENSG00000164175, ENSG00000281919	NA	NA	rs35391-T	rs35391	0	35391	intron_variant	0	NR	3e-10	9.52287874528034		0.44	[0.30-0.58] tanning ability score decrease	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	11q14.3	11	89277878	TYR	TYR			ENSG00000077498	NA	NA	rs1393350-A	rs1393350	0	1393350	intron_variant	0	NR	2e-13	12.698970004336		0.19	[0.13-0.25] tanning ability score increase	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	21q22.3	21	41807559	PRDM15	PRDM15			ENSG00000141956	NA	NA	rs7279297-G	rs7279297	0	7279297	intron_variant	0	NR	3e-06	5.52287874528034		0.12	[0.06-0.18] tanning ability score decrease	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	14q32.2	14	96637470	intergenic	AL137786.1 - RN7SKP108	ENSG00000258702	ENSG00000223299		31496	717	rs17094273-A	rs17094273	0	17094273	intergenic_variant	1	NR	9e-08	7.04575749056067		0.2	[0.12-0.28] tanning ability score increase	Illumina [528173]	N
2009-04-13	19340012	Nan H	2009-04-02	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19340012	Genome-wide association study of tanning phenotype in a population of European ancestry.	Tanning	2,287 European ancestry female individuals	870 European ancestry female individuals	16q24.3	16	89600929	MC1R	CPNE7 - DPEP1	ENSG00000178773	ENSG00000015413		3683	12379	rs154659-C	rs154659	0	154659	regulatory_region_variant	1	NR	7e-08	7.15490195998574		0.14	[0.08-0.20] tanning ability score increase	Illumina [528173]	N
2010-03-30	20212171	Buil A	2010-03-08	Blood	www.ncbi.nlm.nih.gov/pubmed/20212171	C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies.	C4b binding protein levels	352 European ancestry related individuals	NA	1q32.1	1	207096513	C4BPB, C4BPA	C4BPB			ENSG00000123843	NA	NA	rs3813948-C	rs3813948	0	3813948	non_coding_transcript_exon_variant	0		4e-10	9.39794000867204	(%a7b0)	NA		Illumina [283437]	N
2008-06-16	17632545	Hakonarson H	2007-07-15	Nature	www.ncbi.nlm.nih.gov/pubmed/17632545	A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.	Type 1 diabetes	467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls	390 European ancestry trios, 1,333 European ancestry cases from 549 families	11p15.5	11	2148913	INS	INS-IGF2, AC132217.2			ENSG00000129965, ENSG00000284779	NA	NA	rs1004446-C	rs1004446	0	1004446	intron_variant	0	0.65	4e-09	8.39794000867204		1.61	[1.37-1.89]	Illumina [543071]	N
2008-06-16	17632545	Hakonarson H	2007-07-15	Nature	www.ncbi.nlm.nih.gov/pubmed/17632545	A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.	Type 1 diabetes	467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls	390 European ancestry trios, 1,333 European ancestry cases from 549 families	16p13.13	16	11144926	KIAA0350	CLEC16A			ENSG00000038532	NA	NA	rs2903692-G	rs2903692	0	2903692	intron_variant	0	0.62	7e-11	10.1549019599857		1.54	[1.32-1.79]	Illumina [543071]	N
2008-06-16	17632545	Hakonarson H	2007-07-15	Nature	www.ncbi.nlm.nih.gov/pubmed/17632545	A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.	Type 1 diabetes	467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls	390 European ancestry trios, 1,333 European ancestry cases from 549 families	1p13.2	1	113834946	PTPN22	PTPN22, AL137856.1			ENSG00000134242, ENSG00000231128	NA	NA	rs2476601-A	rs2476601	0	2476601	missense_variant	0	0.09	1e-07	7		1.8	[1.44-2.24]	Illumina [543071]	N
2008-06-16	17632545	Hakonarson H	2007-07-15	Nature	www.ncbi.nlm.nih.gov/pubmed/17632545	A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.	Type 1 diabetes	467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls	390 European ancestry trios, 1,333 European ancestry cases from 549 families	6p21.32	6	32700133	HLA-DRB1	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		31750	5991	rs2647044-A	rs2647044	0	2647044	intergenic_variant	1	0.13	1e-16	16		8.3	[6.97-9.89]	Illumina [543071]	N
2010-04-14	20348956	Kiemeney LA	2010-03-28	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20348956	A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.	Urinary bladder cancer	1,889 European ancestry cases, 39,310 European ancestry controls	2,850 European ancestry cases, 6,239 European ancestry controls	8q24.21	8	127705823	MYC	CASC11			ENSG00000249375	NA	NA	rs9642880-T	rs9642880	0	9642880	intron_variant	0	0.44	7e-12	11.1549019599857		1.21	[1.15-1.28]	Illumina [304703]	N
2010-04-14	20348956	Kiemeney LA	2010-03-28	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20348956	A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.	Urinary bladder cancer	1,889 European ancestry cases, 39,310 European ancestry controls	2,850 European ancestry cases, 6,239 European ancestry controls	4p16.3	4	1732512	TMEM129, SLBP, TACC3, FGFR3	TACC3			ENSG00000013810	NA	NA	rs798766-T	rs798766	0	798766	intron_variant	0	0.19	1e-11	11		1.24	[1.17-1.32]	Illumina [304703]	N
2010-04-14	20348956	Kiemeney LA	2010-03-28	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20348956	A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.	Urinary bladder cancer	1,889 European ancestry cases, 39,310 European ancestry controls	2,850 European ancestry cases, 6,239 European ancestry controls	3q28	3	189928144	TP63	TP63 - P3H2	ENSG00000073282	ENSG00000090530		30868	28584	rs710521-A	rs710521	0	710521	intergenic_variant	1	0.73	6e-08	7.22184874961636		1.19	[1.12-1.27]	Illumina [304703]	N
2015-05-20	21221126	Shen Y	2011-01-11	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/21221126	Genome-wide association study of serious blistering skin rash caused by drugs.	Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)	up to 72 European ancestry cases, up to 4,251 European ancestry controls	NA	6p25.2	6	3371057	SLC22A23	SLC22A23			ENSG00000137266	NA	NA	rs981946-?	rs981946	0	981946	intron_variant	0	NR	9e-06	5.04575749056067		2.3	[1.6–3.4]	Illumina [up to 1000000]	N
2015-05-20	21221126	Shen Y	2011-01-11	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/21221126	Genome-wide association study of serious blistering skin rash caused by drugs.	Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)	up to 72 European ancestry cases, up to 4,251 European ancestry controls	NA	20q12	20	40410188	MAFB	AL009050.1 - MAFB	ENSG00000223410	ENSG00000204103		283831	275660	rs6016348-?	rs6016348	0	6016348	regulatory_region_variant	1	NR	1e-06	6		2.9	[1.9–4.5]	Illumina [up to 1000000]	N
2015-05-20	21221126	Shen Y	2011-01-11	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/21221126	Genome-wide association study of serious blistering skin rash caused by drugs.	Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)	up to 72 European ancestry cases, up to 4,251 European ancestry controls	NA	7p21.3	7	7761056	RPA3	AC007161.3, UMAD1			ENSG00000283549, ENSG00000219545	NA	NA	rs17137412-?	rs17137412	0	17137412	intron_variant	0	NR	1e-08	8	(NW-EA)	4	[2.5–6.2]	Illumina [up to 1000000]	N
2015-05-20	21221126	Shen Y	2011-01-11	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/21221126	Genome-wide association study of serious blistering skin rash caused by drugs.	Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN)	up to 72 European ancestry cases, up to 4,251 European ancestry controls	NA	7q21.12	7	87944332	ADAM22	ADAM22			ENSG00000008277	NA	NA	rs12019361-?	rs12019361	0	12019361	intron_variant	0	NR	7e-06	5.15490195998574	(Lamotrigine)	12	[NR]	Illumina [up to 1000000]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	6p22.3	6	24544739	KIAA0319	KIAA0319			ENSG00000137261	NA	NA	rs16889440-?	rs16889440	0	16889440	3_prime_UTR_variant	0	0.18	2e-06	5.69897000433602		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	10p15.3	10	1364169	ADARB2	ADARB2			ENSG00000185736	NA	NA	rs11250464-?	rs11250464	0	11250464	intron_variant	0	0.18	6e-06	5.22184874961636		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	14q32.2	14	97836994	LOC100132612	AL355097.1 - LINC01550	ENSG00000258379	ENSG00000246223		47738	87643	rs1471356-?	rs1471356	0	1471356	intergenic_variant	1	0.23	9e-06	5.04575749056067		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	2p16.3	2	48950462	FSHR	AC009975.1			ENSG00000282890	NA	NA	rs7591064-?	rs7591064	0	7591064	intron_variant	0	0.11	5e-06	5.30102999566398		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	1q43	1	241715245	WDR64	WDR64			ENSG00000162843	NA	NA	rs12569163-?	rs12569163	0	12569163	intron_variant	0	0.12	2e-06	5.69897000433602		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	9p24.1	9	6849317	KDM4C	KDM4C			ENSG00000107077	NA	NA	rs4742269-?	rs4742269	0	4742269	intron_variant	0	0.14	5e-06	5.30102999566398		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	6q25.1	6	149977706	ULBP1	AL355497.1			ENSG00000219298	NA	NA	rs1853665-?	rs1853665	0	1853665	non_coding_transcript_exon_variant	0	0.34	7e-06	5.15490195998574		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	8q22.1	8	95107844	PLEKHF2	NDUFAF6			ENSG00000156170	NA	NA	rs4392868-?	rs4392868	0	4392868	intron_variant	0	0.09	8e-06	5.09691001300806		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	8q22.1	8	95114802	PLEKHF2	NDUFAF6			ENSG00000156170	NA	NA	rs7000734-?	rs7000734	0	7000734	intron_variant	0	0.08	4e-07	6.39794000867204		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	7q21.3	7	96952499	DLX6AS	RN7SL252P - DLX6-AS1	ENSG00000244318	ENSG00000231764		12135	2642	rs17598306-?	rs17598306	0	17598306	intergenic_variant	1	0.08	9e-06	5.04575749056067		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	6p12.1	6	54400598	TINAG	TINAG - CLNS1AP1	ENSG00000137251	ENSG00000213335		10456	84571	rs16885294-?	rs16885294	0	16885294	intergenic_variant	1	0.07	4e-07	6.39794000867204		NA		Affymetrix, Illumina [1348798]	N
2010-11-23	20923822	Niu N	2010-10-05	Genome Res	www.ncbi.nlm.nih.gov/pubmed/20923822	Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines.	Radiation response	93 African American human lymphoblastoid cell lines, 89 European ancestry human lymphoblastoid cell lines, 95 Han Chinese ancestry human lymphoblastoid cell lines	NA	16q23.1	16	78597897	WWOX	WWOX			ENSG00000186153	NA	NA	rs2859631-?	rs2859631	0	2859631	intron_variant	0	0.07	1e-06	6		NA		Affymetrix, Illumina [1348798]	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	1p13.3	1	109457216	AMIGO1, SORT1, ATXN7L2, SYPL2, CYB561D1, PSMA5	PSMA5 - SYPL2	ENSG00000143106	ENSG00000143028		30768	9330	rs1933182-A	rs1933182	0	1933182	intergenic_variant	1	0.3	1e-07	7	(eGFRcrea)	0.01	[0.006-0.010] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	13q21.33	13	71773564	DACH1	DACH1			ENSG00000276644	NA	NA	rs626277-C	rs626277	0	626277	intron_variant	0	0.4	3e-11	10.5228787452803	(eGFRcrea)	0.01	[0.007-0.011] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	15q24.2	15	75866642	UBE2Q2, FBX022	UBE2Q2			ENSG00000140367	NA	NA	rs1394125-A	rs1394125	0	1394125	intron_variant	0	0.35	3e-17	16.5228787452803	(eGFRcrea)	0.01	[0.007-0.011] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	17q23.2	17	61379228	BCAS3, TBX2, C17orf82	AC005746.2, BCAS3			ENSG00000267131, ENSG00000141376	NA	NA	rs9895661-C	rs9895661	0	9895661	non_coding_transcript_exon_variant	0	0.19	1e-15	15	(eGFRcrea)	0.01	[0.007-0.015] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	2p25.2	2	5767748	SOX11	AC010729.1 - LINC01810	ENSG00000236106	ENSG00000237266		37393	42893	rs16864170-C	rs16864170	0	16864170	intergenic_variant	1	0.05	2e-07	6.69897000433602	(CKD)	1.3	[1.18-1.43]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	3q23	3	142088295	TFDP2	TFDP2			ENSG00000114126	NA	NA	rs347685-C	rs347685	0	347685	intron_variant	0	0.28	3e-11	10.5228787452803	(eGFRcrea)	1.09	[0.007-0.011] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	1q21.3	1	150979001	SETDB1, LASS2, ANXA9, PRUNE, FAM63A, BNIPL	AL590133.1 - ANXA9	ENSG00000231073	ENSG00000143412		3467	3248	rs267734-C	rs267734	0	267734	regulatory_region_variant	1	0.2	1e-12	12	(eGFRcrea)	0.01	[0.004-0.016] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	19q13.11	19	32865985	CCDC123, ECAT8, SLC7A9	SLC7A9			ENSG00000021488	NA	NA	rs12460876-C	rs12460876	0	12460876	intron_variant	0	0.39	3e-15	14.5228787452803	(eGFRcrea)	0.01	[0.006-0.01] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	6q25.3	6	160247357	SLC22A2	SLC22A2			ENSG00000112499	NA	NA	rs2279463-G	rs2279463	0	2279463	intron_variant	0	0.12	6e-12	11.2218487496164	(eGFRcrea)	0.01	[0.009-0.017] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	12p13.33	12	240132	SLC6A13, JARID1A, SLC6A12	SLC6A13			ENSG00000010379	NA	NA	rs10774021-C	rs10774021	0	10774021	intron_variant	0	0.36	1e-09	9	(eGFRcrea)	1.05	[0.006-0.010] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	6p21.1	6	43838872	VEGFA	AL157371.2			ENSG00000283573	NA	NA	rs881858-G	rs881858	0	881858	intron_variant	0	0.28	9e-14	13.0457574905607	(eGFRcrea)	1.08	[0.007-0.015] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	7q36.1	7	151710715	PRKAG2	PRKAG2			ENSG00000106617	NA	NA	rs7805747-A	rs7805747	0	7805747	intron_variant	0	0.24	4e-12	11.397940008672	(CKD)	1.18	[1.12-1.25]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	11q13.1	11	65739351	RNASEH2C, KAT5, OVOL1	KRT8P26 - AP001266.2	ENSG00000214659	ENSG00000255557		11137	6378	rs4014195-G	rs4014195	0	4014195	intergenic_variant	1	0.35	1e-07	7	(eGFRcrea)	0.01	[0.006-0.010] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	2p13.1	2	73641201	NAT8, NAT8B, ALMS1	NAT8, ALMS1P1			ENSG00000144035, ENSG00000163016	NA	NA	rs13538-G	rs13538	0	13538	missense_variant	0	0.23	5e-14	13.301029995664	(eGFRcrea)	0.01	[0.005-0.013] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	7q11.23	7	77787122	PHTF2, RSBN1L, TMEM60	RSBN1L - TMEM60	ENSG00000187257	ENSG00000135211		4100	6606	rs6465825-C	rs6465825	0	6465825	intergenic_variant	1	0.39	2e-09	8.69897000433602	(eGFRcrea)	0.01	[0.006-0.01] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	4q21.1	4	76447694	CCDC158, SHROOM3	SHROOM3			ENSG00000138771	NA	NA	rs17319721-A	rs17319721	0	17319721	intron_variant	0	0.43	1e-19	19	(eGFRcrea)	NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	15q21.1	15	45349027	SPATA5L1, GATM	AC051619.3 - RNU6-953P	ENSG00000259433	ENSG00000238941		16393	5752	rs2453533-?	rs2453533	0	2453533	intergenic_variant	1	0.38	5e-22	21.301029995664	(eGFRcrea)	NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	16p12.3	16	20356368	UMOD, ACSM5, GP2, PDILT	UMOD - PDILT	ENSG00000169344	ENSG00000169340		67	2807	rs12917707-T	rs12917707	0	12917707	intergenic_variant	1	0.18	1e-20	20	(eGFRcrea)	NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	8p21.2	8	23893638	STC1	STC1 - RNU1-148P	ENSG00000159167	ENSG00000207201		38832	183359	rs10109414-T	rs10109414	0	10109414	regulatory_region_variant	1	0.42	1e-08	8	(eGFRcrea)	NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	20p11.21	20	23632100	CST9, CST3, CST4	CST3, AL121894.2			ENSG00000101439, ENSG00000270001	NA	NA	rs911119-?	rs911119	0	911119	non_coding_transcript_exon_variant	0	0.21	2e-138	137.698970004336	(eGFRcys)	NA		Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	2p23.3	2	27508073	FNDC4, IFT172, GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-T	rs1260326	0	1260326	missense_variant	0	0.41	3e-14	13.5228787452803	(eGFRcrea)	0.01	[0.007-0.011] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	5p13.1	5	39397030	DAB2, C9	C9, DAB2			ENSG00000113600, ENSG00000153071	NA	NA	rs11959928-A	rs11959928	0	11959928	intron_variant	0	0.44	1e-07	7	(eGFRcrea)	0.01	[0.007-0.011] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	5q35.3	5	177390635	RGS14, PRR7, PFN3, GRK6, SLC34A1, F12, LMAN2	SLC34A1			ENSG00000131183	NA	NA	rs6420094-G	rs6420094	0	6420094	intron_variant	0	0.34	1e-14	14	(eGFRcrea)	0.01	[0.007-0.015] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	12q24.12	12	111569952	ATXN2	ATXN2			ENSG00000204842	NA	NA	rs653178-T	rs653178	0	653178	intron_variant	0	0.5	4e-11	10.397940008672	(eGFRcys)	0.01	[0.009-0.017] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	2q34	2	210675783	CPS1	CPS1			ENSG00000021826	NA	NA	rs7422339-A	rs7422339	1	1047891	missense_variant	0	0.32	1e-15	15	(eGFRcrea)	0.01	[0.005-0.013] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-T	rs1260326	0	1260326	missense_variant	0	NR	5e-40	39.301029995664		0.072	[0.06-0.08] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	2q14.1	2	113083453	IL1F10	IL1F10 - RNU6-1180P	ENSG00000136697	ENSG00000201805		7610	3352	rs6734238-G	rs6734238	0	6734238	regulatory_region_variant	1	NR	2e-17	16.698970004336		0.05	[0.04-0.06] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	15q22.2	15	60602766	RORA	RORA, RORA-AS1			ENSG00000069667, ENSG00000245534	NA	NA	rs340029-T	rs340029	0	340029	intron_variant	0	NR	4e-09	8.39794000867204		0.032	[0.02-0.04] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	7q11.23	7	73556901	BCL7B	BCL7B			ENSG00000106635	NA	NA	rs13233571-C	rs13233571	0	13233571	intron_variant	0	NR	4e-09	8.39794000867204		0.054	[0.03-0.07] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	21q22.2	21	39093608	PSMG1	AF064858.1 - RPL23AP12	ENSG00000235888	ENSG00000228861		30714	33960	rs2836878-G	rs2836878	0	2836878	intergenic_variant	1	NR	2e-07	6.69897000433602		0.032	[0.02-0.04] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	14q24.2	14	72552528	RGS6	RGS6			ENSG00000182732	NA	NA	rs4903031-G	rs4903031	0	4903031	intron_variant	0	NR	5e-06	5.30102999566398		0.032	[0.02-0.04] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	12q24.31	12	120983004	HNF1A	HNF1A			ENSG00000135100	NA	NA	rs1183910-G	rs1183910	0	1183910	intron_variant	0	NR	2e-124	123.698970004336		0.149	[0.14-0.16] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	1p31.3	1	65695778	LEPR	LEPR - AL513493.1	ENSG00000116678	ENSG00000285079		54219	8184	rs4420065-C	rs4420065	0	4420065	intergenic_variant	1	NR	4e-62	61.397940008672		0.09	[0.08-0.10] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	1q21.3	1	154453788	IL6R	IL6R			ENSG00000160712	NA	NA	rs4129267-C	rs4129267	0	4129267	intron_variant	0	NR	2e-48	47.698970004336		0.079	[0.07-0.09] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	12q23.2	12	103089316	ASCL1	AC068643.1			ENSG00000257703	NA	NA	rs10745954-A	rs10745954	0	10745954	intron_variant	0	NR	2e-11	10.698970004336		0.039	[0.03-0.05] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	1p34.3	1	39599289	PABPC4	PABPC4 - HEYL	ENSG00000090621	ENSG00000163909		22499	24146	rs12037222-A	rs12037222	0	12037222	regulatory_region_variant	1	NR	6e-11	10.2218487496164		0.045	[0.03-0.06] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	20q13.12	20	44413724	HNF4A	HNF4A			ENSG00000101076	NA	NA	rs1800961-C	rs1800961	0	1800961	missense_variant	0	NR	2e-09	8.69897000433602		0.088	[0.06-0.12] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	16q12.1	16	51124799	SALL1	SOD1P2 - SALL1	ENSG00000261282	ENSG00000103449		16778	11176	rs10521222-C	rs10521222	0	10521222	intergenic_variant	1	NR	9e-13	12.0457574905607		0.104	[0.07-0.13] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	18p11.21	18	12821594	PTPN2	PTPN2			ENSG00000175354	NA	NA	rs2847281-A	rs2847281	0	2847281	intron_variant	0	NR	2e-08	7.69897000433602		0.031	[0.02-0.04] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	5q31.1	5	132503926	IRF1	AC116366.3			ENSG00000283782	NA	NA	rs4705952-G	rs4705952	0	4705952	intron_variant	0	NR	1e-08	8		0.042	[0.03-0.05] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	1q44	1	247438293	NLRP3	NLRP3			ENSG00000162711	NA	NA	rs12239046-C	rs12239046	0	12239046	intron_variant	0	NR	1e-15	15		0.047	[0.04-0.06] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	19q13.32	19	44919689	APOC1	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-A	rs4420638	0	4420638	regulatory_region_variant	1	NR	9e-139	138.045757490561		0.236	[0.22-0.26] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	8p23.1	8	9325848	PPP1R3B	AC022784.1			ENSG00000248538	NA	NA	rs9987289-A	rs9987289	0	9987289	non_coding_transcript_exon_variant	0	NR	3e-13	12.5228787452803		0.069	[0.05-0.09] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	1q23.2	1	159709026	CRP	CRPP1 - CRP	ENSG00000223603	ENSG00000132693		3419	3263	rs2794520-C	rs2794520	0	2794520	intergenic_variant	1	NR	2e-186	185.698970004336		0.16	[0.15-0.17] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-05-23	21300955	Dehghan A	2011-02-07	Circulation	www.ncbi.nlm.nih.gov/pubmed/21300955	Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.	C-reactive protein levels	63,678 European ancestry individuals 1,792 Erasmus Rucphen individuals, 715 Orcadian individuals	16,540 European ancestry individuals	6q22.1	6	116792862	GPRC6A	GPRC6A			ENSG00000173612	NA	NA	rs6901250-A	rs6901250	0	6901250	synonymous_variant	0	NR	5e-08	7.30102999566398		0.035	[0.03-0.05] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	10p15.3	10	1110225	WDR37	WDR37			ENSG00000047056	NA	NA	rs10794720-T	rs10794720	0	10794720	intron_variant	0	0.08	1e-08	8	(eGFRcrea)	0.01	[0.010-0.018] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	15q21.3	15	53654396	WDR72	WDR72			ENSG00000166415	NA	NA	rs491567-C	rs491567	0	491567	intron_variant	0	0.22	3e-13	12.5228787452803	(eGFRcrea)	0.01	[0.005-0.013] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-05-05	20383146	Kottgen A	2010-04-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20383146	New loci associated with kidney function and chronic kidney disease.	Chronic kidney disease	Up to 67,093 European ancestry individuals	Up to 22,982 European ancestry individuals	9q21.11	9	68819791	PIP5K1B, FAM122A	PIP5K1B			ENSG00000107242	NA	NA	rs4744712-A	rs4744712	0	4744712	intron_variant	0	0.39	8e-14	13.0969100130081	(eGFRcrea)	0.01	[0.008-0.016] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-03-31	19300482	Pillai SG	2009-03-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19300482	A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.	Chronic obstructive pulmonary disease	823 cases, 810 controls	1,891 European ancestry individuals from 606 families, 389 European ancestry cases, 472 European ancestry controls, 949 individuals from 127 families	15q25.1	15	78513681	CHRNA5, CHRNA3, CHRNA4, LOC123688	HYKK			ENSG00000188266	NA	NA	rs8034191-C	rs8034191	0	8034191	intron_variant	0	0.33	1e-10	10		1.4	[1.18-1.67]	Illumina [493609]	N
2009-03-31	19300482	Pillai SG	2009-03-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19300482	A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.	Chronic obstructive pulmonary disease	823 cases, 810 controls	1,891 European ancestry individuals from 606 families, 389 European ancestry cases, 472 European ancestry controls, 949 individuals from 127 families	4q31.21	4	144559628	HHIP	AC098588.3, AC098588.2			ENSG00000285783, ENSG00000285713	NA	NA	rs1828591-?	rs1828591	0	1828591	intron_variant	0	NR	1e-07	7		1.38	[1.17-1.63]	Illumina [493609]	N
2011-05-26	21544081	Dorajoo R	2011-04-19	Int J Obes (Lond)	www.ncbi.nlm.nih.gov/pubmed/21544081	Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.	Obesity	5,429 Chinese ancestry individuals, 2,431 Malay ancestry individuals, 2,531 Asian Indian ancestry individuals	NA	16q12.2	16	53769662	FTO	FTO			ENSG00000140718	NA	NA	rs1558902-T	rs1558902	0	1558902	intron_variant	0	NR	1e-07	7		0.09	[0.06-0.12] unit decrease	Illumina [1283957] (imputed)	N
2010-05-03	20363506	Meguro A	2010-04-02	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/20363506	Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.	Glaucoma	305 Japanese ancestry cases, 355 Japanese ancestry controls	NA	2p21	2	45419685	SRBD1	SRBD1			ENSG00000068784	NA	NA	rs3213787-A	rs3213787	0	3213787	intron_variant	0	0.81	3e-09	8.52287874528034		2.8	[1.96-3.99]	Affymetrix [325947]	N
2010-05-03	20363506	Meguro A	2010-04-02	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/20363506	Genome-wide association study of normal tension glaucoma: common variants in SRBD1 and ELOVL5 contribute to disease susceptibility.	Glaucoma	305 Japanese ancestry cases, 355 Japanese ancestry controls	NA	6p12.1	6	53258320	ELOVL5	HMGB1P20 - ELOVL5	ENSG00000219163	ENSG00000012660		22023	9078	rs735860-C	rs735860	0	735860	regulatory_region_variant	1	0.48	4e-06	5.39794000867204		1.69	[1.36-2.11]	Affymetrix [325947]	N
2012-02-14	22232737	Shu XO	2012-01-09	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/22232737	Novel genetic markers of breast cancer survival identified by a genome-wide association study.	Breast cancer (survival)	1,950 Chinese ancestry cases	4,160 Chinese ancestry cases	16q22.3	16	73405456	intergenic	LINC01568, ZFHX3			ENSG00000258779, ENSG00000140836	NA	NA	rs9934948-C	rs9934948	0	9934948	intron_variant	0	NR	6e-06	5.22184874961636	(Total Mortality)	1.29	[1.16-1.44]	Affymetrix [613031]	N
2012-02-14	22232737	Shu XO	2012-01-09	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/22232737	Novel genetic markers of breast cancer survival identified by a genome-wide association study.	Breast cancer (survival)	1,950 Chinese ancestry cases	4,160 Chinese ancestry cases	14q24.1	14	68283210	RAD51L1	RAD51B			ENSG00000182185	NA	NA	rs3784099-A	rs3784099	0	3784099	intron_variant	0	NR	1e-07	7	(Total Mortality)	1.49	[1.28-1.72]	Affymetrix [613031]	N
2012-02-14	22232737	Shu XO	2012-01-09	Cancer Res	www.ncbi.nlm.nih.gov/pubmed/22232737	Novel genetic markers of breast cancer survival identified by a genome-wide association study.	Breast cancer (survival)	1,950 Chinese ancestry cases	4,160 Chinese ancestry cases	14q24.1	14	68283210	RAD51L1	RAD51B			ENSG00000182185	NA	NA	rs3784099-A	rs3784099	0	3784099	intron_variant	0	NR	3e-07	6.52287874528034	(Recurrence)	1.43	[1.25-1.64]	Affymetrix [613031]	N
2009-08-21	19648920	Wu X	2009-08-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19648920	Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer.	Bladder cancer	969 European ancestry cases, 957 European ancestry controls	5,698 European ancestry cases, 38,633 European ancestry controls	8q24.3	8	142680513	PSCA	PSCA, JRK			ENSG00000167653, ENSG00000234616	NA	NA	rs2294008-T	rs2294008	0	2294008	5_prime_UTR_variant	0	0.46	2e-10	9.69897000433602		1.15	[1.10-1.20]	Illumina [556429]	N
2013-09-21	23678272	Cheong KA	2013-05-02	J Korean Med Sci	www.ncbi.nlm.nih.gov/pubmed/23678272	Three new single nucleotide polymorphisms identified by a genome-wide association study in Korean patients with vitiligo.	Vitiligo (non-segmental)	20 Korean ancestry cases, 192 Korean ancestry controls	184 Korean ancestry cases, 192 Korean ancestry controls	16q12.2	16	53605526	KIAA1005	RPGRIP1L			ENSG00000103494	NA	NA	rs3213758-A	rs3213758	0	3213758	missense_variant	0	.497	6e-11	10.2218487496164		2.77	[2.04-3.76]	Affymetrix [500568]	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	1p36.22	1	10736809	CASZ1	CASZ1			ENSG00000130940	NA	NA	rs880315-C	rs880315	0	880315	intron_variant	0	0.65	7e-07	6.15490195998574	(Systolic)	0.74	[0.45-1.03] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	10q24.32	10	103086421	NT5C2, CNNM2, CYP17A1	CNNM2			ENSG00000148842	NA	NA	rs11191548-T	rs11191548	0	11191548	3_prime_UTR_variant	0	0.74	4e-17	16.397940008672	(Systolic)	1.18	[0.91-1.45] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	1p13.2	1	112648185	ST7L, CAPZA1	CAPZA1			ENSG00000116489	NA	NA	rs17030613-C	rs17030613	0	17030613	intron_variant	0	0.49	8e-06	5.09691001300806	(Systolic)	0.49	[0.27-0.71] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	2q24.3	2	164050310	GRB14, FIGN	AC016766.1			ENSG00000237844	NA	NA	rs16849225-C	rs16849225	0	16849225	intron_variant	0	0.61	4e-11	10.397940008672	(Systolic)	0.75	[0.53-0.97] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	4q25	4	110460482	ENPEP	ENPEP			ENSG00000138792	NA	NA	rs6825911-C	rs6825911	0	6825911	intron_variant	0	0.51	7e-08	7.15490195998574	(Systolic)	0.6	[0.38-0.82] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	5p13.3	5	32804422	NPR3	NPR3 - AC025459.1	ENSG00000113389	ENSG00000251062		12698	83568	rs1173766-C	rs1173766	0	1173766	intergenic_variant	1	0.60	2e-08	7.69897000433602	(Systolic)	0.63	[0.41-0.85] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	12q24.13	12	112379979	RPL6, ALDH2, PTPN11	HECTD4			ENSG00000173064	NA	NA	rs11066280-T	rs11066280	0	11066280	intron_variant	0	0.75	8e-31	30.0969100130081	(Systolic)	1.56	[1.31-1.81] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	12q24.21	12	115114632	TBX3	AC008125.1 - AC078880.1	ENSG00000257958	ENSG00000257519		34479	148538	rs35444-A	rs35444	0	35444	intergenic_variant	1	0.75	8e-07	6.09691001300806	(Systolic)	0.63	[0.38-0.88] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	12q21.33	12	89666809	ATP2B1	ATP2B1			ENSG00000070961	NA	NA	rs17249754-G	rs17249754	0	17249754	intron_variant	0	0.64	8e-20	19.0969100130081	(Systolic)	1.17	[0.92-1.42] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	5p13.3	5	32804422	NPR3	NPR3 - AC025459.1	ENSG00000113389	ENSG00000251062		12698	83568	rs1173766-C	rs1173766	0	1173766	intergenic_variant	1	0.60	1e-07	7	(Diastolic)	0.36	[0.22-0.50] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	12q24.21	12	115114632	TBX3	AC008125.1 - AC078880.1	ENSG00000257958	ENSG00000257519		34479	148538	rs35444-A	rs35444	0	35444	intergenic_variant	1	0.75	1e-10	10	(Diastolic)	0.5	[0.34-0.66] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	12q21.33	12	89666809	ATP2B1	ATP2B1			ENSG00000070961	NA	NA	rs17249754-G	rs17249754	0	17249754	intron_variant	0	0.64	2e-13	12.698970004336	(Diastolic)	0.58	[0.42-0.74] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	1p36.22	1	10736809	CASZ1	CASZ1			ENSG00000130940	NA	NA	rs880315-C	rs880315	0	880315	intron_variant	0	0.65	3e-10	9.52287874528034	(Diastolic)	0.56	[0.38-0.74] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	1p13.2	1	112648185	ST7L, CAPZA1	CAPZA1			ENSG00000116489	NA	NA	rs17030613-C	rs17030613	0	17030613	intron_variant	0	0.49	1e-08	8	(Diastolic)	0.38	[0.24-0.52] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	4q25	4	110460482	ENPEP	ENPEP			ENSG00000138792	NA	NA	rs6825911-C	rs6825911	0	6825911	intron_variant	0	0.51	9e-09	8.04575749056067	(Diastolic)	0.39	[0.25-0.53] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	12q24.13	12	112379979	RPL6, ALDH2, PTPN11	HECTD4			ENSG00000173064	NA	NA	rs11066280-T	rs11066280	0	11066280	intron_variant	0	0.75	1e-35	35	(Diastolic)	1.01	[0.85-1.17] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2011-07-13	21572416	Kato N	2011-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21572416	Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.	Blood pressure	19,608 East Asian ancestry individuals	30,765 East Asian ancestry individuals	10q24.32	10	103086421	NT5C2, CNNM2, CYP17A1	CNNM2			ENSG00000148842	NA	NA	rs11191548-T	rs11191548	0	11191548	3_prime_UTR_variant	0	0.74	7e-12	11.1549019599857	(Diastolic)	0.58	[0.42-0.74] mm Hg increase	Affymetrix, Illumina [1700000] (imputed)	N
2009-09-09	19684573	Ge D	2009-08-16	Nature	www.ncbi.nlm.nih.gov/pubmed/19684573	Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.	Response to hepatitis C treatment	871 European ancestry cases, 191 African American cases, 75 Hispanic cases	NA	4q34.3	4	179127208	intergenic	AC018710.1 - AC020551.1	ENSG00000250839	ENSG00000250993		57614	261926	rs17067123-?	rs17067123	0	17067123	intergenic_variant	1	NR	8e-06	5.09691001300806	(combined)	NA		Illumina [565759]	N
2009-09-09	19684573	Ge D	2009-08-16	Nature	www.ncbi.nlm.nih.gov/pubmed/19684573	Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.	Response to hepatitis C treatment	871 European ancestry cases, 191 African American cases, 75 Hispanic cases	NA	6q21	6	109686444	AKD2	AK9			ENSG00000155085	NA	NA	rs9400317-?	rs9400317	0	9400317	intron_variant	0	NR	7e-06	5.15490195998574	(combined)	NA		Illumina [565759]	N
2009-09-09	19684573	Ge D	2009-08-16	Nature	www.ncbi.nlm.nih.gov/pubmed/19684573	Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance.	Response to hepatitis C treatment	871 European ancestry cases, 191 African American cases, 75 Hispanic cases	NA	19q13.2	19	39248147	IL28B	IFNL4			ENSG00000272395	NA	NA	rs12979860-C	rs12979860	0	12979860	intron_variant	0	0.72	1e-28	28	(combined, EA)	2	[1.8-2.3]	Illumina [565759]	N
2011-01-16	21302353	Perroud N	2010-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/21302353	Genome-wide association study of hoarding traits.	Hoarding	3,304 European ancestry individuals	NA	5q11.2	5	58025127	intergenic	LINC02225 - LINC02101	ENSG00000249584	ENSG00000248132		125965	82504	rs1844437-C	rs1844437	0	1844437	intergenic_variant	1	0.22	2e-06	5.69897000433602		0.62	[NR] unit decrease	Illumina [1517033] (imputed)	N
2011-01-16	21302353	Perroud N	2010-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/21302353	Genome-wide association study of hoarding traits.	Hoarding	3,304 European ancestry individuals	NA	15q26.2	15	94146424	intergenic	LINC01581 - AC110027.1	ENSG00000259724	ENSG00000258570		38486	21925	rs2388436-G	rs2388436	0	2388436	intergenic_variant	1	0.42	6e-06	5.22184874961636		0.51	[NR] unit increase	Illumina [1517033] (imputed)	N
2011-01-16	21302353	Perroud N	2010-12-28	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/21302353	Genome-wide association study of hoarding traits.	Hoarding	3,304 European ancestry individuals	NA	6q14.1	6	79547564	LCA5	AL391840.3 - AL391840.2	ENSG00000287811	ENSG00000261970		7588	5230	rs3747767-A	rs3747767	0	3747767	intergenic_variant	1	0.03	7e-07	6.15490195998574		1.81	[NR] unit increase	Illumina [1517033] (imputed)	N
2011-01-16	21186350	Zhou K	2010-12-26	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21186350	Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes.	Response to metformin in type 2 diabetes (glycemic)	1,024 European ancestry cases	2,896 European ancestry cases	11q22.3	11	108412434	ATM, C111orf65	C11orf65			ENSG00000166323	NA	NA	rs11212617-C	rs11212617	0	11212617	intron_variant	0	0.44	3e-09	8.52287874528034		1.35	[1.22-1.49]	Affymetrix [705125]	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	4q32.3	4	163611649	MARCH1	MARCH1			ENSG00000145416	NA	NA	rs3792615-T	rs3792615	0	3792615	intron_variant	0	0.95	9e-06	5.04575749056067	(Indian)	1.93	[1.45-2.59]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	1q42.2	1	233204408	PCNXL2	PCNX2			ENSG00000135749	NA	NA	rs12027542-A	rs12027542	0	12027542	intron_variant	0	0.61	4e-07	6.39794000867204	(Malay)	1.41	[1.23-1.61]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	18p11.31	18	2948031	LPIN2	LPIN2			ENSG00000101577	NA	NA	rs10460009-C	rs10460009	0	10460009	intron_variant	0	0.60	9e-06	5.04575749056067	(Malay)	1.35	[1.18-1.54]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	6p22.3	6	20652486	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs9295474-G	rs9295474	0	9295474	intron_variant	0	0.36	9e-06	5.04575749056067	(Chinese+Malay+Indian)	1.16	[1.09-1.24]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	2p25.3	2	3793830	intergenic	DCDC2C			ENSG00000214866	NA	NA	rs11677370-T	rs11677370	0	11677370	intron_variant	0	0.40	3e-06	5.52287874528034	(Indian)	1.35	[1.19-1.53]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	15q24.3	15	77485290	HMG20A	AC090984.1, HMG20A			ENSG00000279033, ENSG00000140382	NA	NA	rs7119-T	rs7119	0	7119	3_prime_UTR_variant	0	0.19	5e-07	6.30102999566398	(Chinese+Malay+Indian)	1.24	[1.14-1.34]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	21q22.11	21	32012873	HUNK	HUNK			ENSG00000142149	NA	NA	rs2833610-A	rs2833610	0	2833610	intron_variant	0	0.57	4e-06	5.39794000867204	(Chinese+Malay+Indian)	1.17	[1.09-1.24]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	10q23.33	10	92588073	KIF11	IDE - KIF11	ENSG00000119912	ENSG00000138160		13980	5057	rs6583826-G	rs6583826	0	6583826	intergenic_variant	1	0.26	7e-06	5.15490195998574	(Chinese+Malay+Indian)	1.18	[1.10-1.27]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	3q26.33	3	179943530	PEX5L	PEX5L			ENSG00000114757	NA	NA	rs7630877-A	rs7630877	0	7630877	intron_variant	0	0.17	7e-06	5.15490195998574	(Chinese)	1.32	[1.17-1.49]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	1q32.2	1	207478831	CR2	CR2			ENSG00000117322	NA	NA	rs17045328-G	rs17045328	0	17045328	intron_variant	0	0.30	7e-06	5.15490195998574	(Malay)	1.38	[1.20-1.59]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	6q13	6	70579486	C6orf57	SDHAF4			ENSG00000154079	NA	NA	rs1048886-G	rs1048886	0	1048886	missense_variant	0	0.18	3e-08	7.52287874528034	(Indian)	1.54	[1.32-1.80]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	6q24.1	6	139952510	intergenic	AL050338.2			ENSG00000287820	NA	NA	rs642858-A	rs642858	0	642858	intron_variant	0	0.40	2e-06	5.69897000433602	(Indian)	1.35	[1.19-1.53]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	7q22.1	7	100892456	ACHE	ACHE			ENSG00000087085	NA	NA	rs7636-A	rs7636	0	7636	synonymous_variant	0	0.06	5e-06	5.30102999566398	(Indian)	1.85	[1.42-2.41]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	10q26.3	10	131149699	TCERG1L	TCERG1L			ENSG00000176769	NA	NA	rs10741243-G	rs10741243	0	10741243	intron_variant	0	0.93	5e-06	5.30102999566398	(Indian)	1.75	[1.38-2.23]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	3q12.3	3	102484201	ZPLD1	ZPLD1 - AC063938.1	ENSG00000170044	ENSG00000241754		4360	136860	rs2063640-A	rs2063640	0	2063640	regulatory_region_variant	1	0.17	3e-06	5.52287874528034	(Chinese+Malay+Indian)	1.23	[1.13-1.34]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	19q13.2	19	39090097	FLJ16165	ACP7			ENSG00000183760	NA	NA	rs472265-G	rs472265	0	472265	intron_variant	0	0.22	9e-06	5.04575749056067	(Indian)	1.39	[1.20-1.61]	Illumina [~ 2000000] (imputed)	N
2011-05-24	21490949	Sim X	2011-04-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21490949	Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.	Type 2 diabetes	2,010 Chinese ancestry cases, 1,945 Chinese ancestry controls, 794 Malay ancestry cases, 1,240 Malay ancestry controls, 977 Asian Indian ancestry cases, 1,169 Asian Indian ancestry controls	NA	3q23	3	142712158	PLS1	AC072028.1, PLS1			ENSG00000287045, ENSG00000120756	NA	NA	rs3773506-C	rs3773506	0	3773506	3_prime_UTR_variant	0	0.06	9e-06	5.04575749056067	(Indian)	1.81	[1.39-2.35]	Illumina [~ 2000000] (imputed)	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	5q13.3	5	75355259	HMGCR	HMGCR			ENSG00000113161	NA	NA	rs3846662-G	rs3846662	0	3846662	non_coding_transcript_exon_variant	0	0.44	3e-19	18.5228787452803		0.09	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	7p15.3	7	21567734	DNAH11	DNAH11			ENSG00000105877	NA	NA	rs12670798-G	rs12670798	0	12670798	intron_variant	0	0.24	9e-07	6.04575749056067		0.06	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	11q23.3	11	116733008	APOA1, APOC3, APOA4, APOA5	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		74713	15162	rs12272004-C	rs12272004	0	12272004	TF_binding_site_variant	1	0.93	7e-07	6.15490195998574		0.11	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	15q21.3	15	58391167	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs1532085-G	rs1532085	0	1532085	intron_variant	0	0.59	4e-07	6.39794000867204		0.05	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	19p13.2	19	11100236	LDLR	LDLR			ENSG00000130164	NA	NA	rs2228671-G	rs2228671	0	2228671	stop_gained	0	0.88	9e-24	23.0457574905607		0.16	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	18q21.1	18	49640844	LIPG	LIPG - SMUG1P1	ENSG00000101670	ENSG00000267444		41659	9506	rs4939883-G	rs4939883	0	4939883	TF_binding_site_variant	1	0.83	2e-11	10.698970004336		0.07	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	19q13.32	19	44892362	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-G	rs2075650	0	2075650	intron_variant	0	0.15	3e-19	18.5228787452803		0.14	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	11q12.2	11	61829740	FADS2, FADS3	FADS2			ENSG00000134824	NA	NA	rs174570-G	rs174570	0	174570	intron_variant	0	0.83	2e-10	9.69897000433602		0.09	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	1p36.11	1	25442446	TMEM57	MACO1			ENSG00000204178	NA	NA	rs10903129-G	rs10903129	0	10903129	intron_variant	0	0.54	5e-10	9.30102999566398		0.06	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	2p21	2	43837951	ABCG5	ABCG8, ABCG5			ENSG00000143921, ENSG00000138075	NA	NA	rs6756629-G	rs6756629	0	6756629	missense_variant	0	0.92	2e-11	10.698970004336		0.15	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	1p31.3	1	62652525	DOCK7	DOCK7			ENSG00000116641	NA	NA	rs10889353-C	rs10889353	0	10889353	intron_variant	0	0.32	4e-12	11.397940008672		0.08	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	2p24.1	2	21009323	APOB	APOB			ENSG00000084674	NA	NA	rs693-G	rs693	0	693	synonymous_variant	0	0.52	9e-23	22.0457574905607		0.1	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	19p13.11	19	19678719	NCAN	ZNF101			ENSG00000181896	NA	NA	rs2304130-G	rs2304130	0	2304130	splice_region_variant	0	0.07	2e-15	14.698970004336		0.15	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	1p13.3	1	109275908	CELSR2	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		157	3648	rs646776-G	rs646776	0	646776	intergenic_variant	1	0.22	9e-22	21.0457574905607		0.13	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Cholesterol, total	21,848 European ancestry individuals, 714 Orcadian individuals	NA	8q24.13	8	125492484	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs6987702-G	rs6987702	0	6987702	intron_variant	0	0.29	3e-09	8.52287874528034		0.07	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	19p13.11	19	19678719	NCAN	ZNF101			ENSG00000181896	NA	NA	rs2304130-G	rs2304130	0	2304130	splice_region_variant	0	0.07	3e-06	5.52287874528034		0.12	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	7p15.3	7	21567734	DNAH11	DNAH11			ENSG00000105877	NA	NA	rs12670798-G	rs12670798	0	12670798	intron_variant	0	0.24	6e-09	8.22184874961636		0.09	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	11q12.2	11	61829740	FADS2, FADS3	FADS2			ENSG00000134824	NA	NA	rs174570-G	rs174570	0	174570	intron_variant	0	0.83	4e-13	12.397940008672		0.11	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	5q13.3	5	75355259	HMGCR	HMGCR			ENSG00000113161	NA	NA	rs3846662-G	rs3846662	0	3846662	non_coding_transcript_exon_variant	0	0.44	2e-11	10.698970004336		0.08	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	8q24.13	8	125492484	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs6987702-G	rs6987702	0	6987702	intron_variant	0	0.29	3e-06	5.52287874528034		0.07	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	19p13.2	19	11100236	LDLR	LDLR			ENSG00000130164	NA	NA	rs2228671-G	rs2228671	0	2228671	stop_gained	0	0.88	4e-14	13.397940008672		0.14	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	19q13.32	19	44892009	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs157580-G	rs157580	0	157580	intron_variant	0	0.33	2e-19	18.698970004336		0.11	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	2p21	2	43837951	ABCG5	ABCG8, ABCG5			ENSG00000143921, ENSG00000138075	NA	NA	rs6756629-G	rs6756629	0	6756629	missense_variant	0	0.92	3e-10	9.52287874528034		0.16	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	2p24.1	2	21009323	APOB	APOB			ENSG00000084674	NA	NA	rs693-G	rs693	0	693	synonymous_variant	0	0.52	4e-17	16.397940008672		0.1	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	1p31.3	1	62652525	DOCK7	DOCK7			ENSG00000116641	NA	NA	rs10889353-C	rs10889353	0	10889353	intron_variant	0	0.32	8e-06	5.09691001300806		0.06	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	11q23.3	11	116733008	APOA1, APOC3, APOA4, APOA5	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		74713	15162	rs12272004-C	rs12272004	0	12272004	TF_binding_site_variant	1	0.93	5e-13	12.301029995664		0.18	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	LDL cholesterol	17,083 European ancestry individuals, 714 Orcadian individuals	NA	1p13.3	1	109275908	CELSR2	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		157	3648	rs646776-G	rs646776	0	646776	intergenic_variant	1	0.22	8e-23	22.0969100130081		0.16	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	2p24.1	2	20983311	APOB	LINC02850 - AC115619.1	ENSG00000236436	ENSG00000261012		121650	16002	rs6754295-C	rs6754295	0	6754295	regulatory_region_variant	1	0.25	3e-08	7.52287874528034		0.08	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	8p21.3	8	19973410	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		6151	105704	rs10096633-G	rs10096633	0	10096633	regulatory_region_variant	1	0.88	2e-18	17.698970004336		0.17	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	19q13.32	19	44911194	APOE, TOMM40	AC011481.3			ENSG00000280087	NA	NA	rs439401-G	rs439401	0	439401	non_coding_transcript_exon_variant	0	0.68	2e-09	8.69897000433602		0.09	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	1p31.3	1	62465961	DOCK7	DOCK7			ENSG00000116641	NA	NA	rs1167998-C	rs1167998	0	1167998	intron_variant	0	0.32	2e-12	11.698970004336		0.09	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	19p13.11	19	19678719	NCAN	ZNF101			ENSG00000181896	NA	NA	rs2304130-G	rs2304130	0	2304130	splice_region_variant	0	0.07	3e-06	5.52287874528034		0.1	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	11q23.3	11	116733008	APOA1, APOC3, APOA4, APOA5	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		74713	15162	rs12272004-C	rs12272004	0	12272004	TF_binding_site_variant	1	0.93	5e-13	12.301029995664		0.18	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-G	rs780094	0	780094	intron_variant	0	0.63	3e-20	19.5228787452803		0.1	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	Triglycerides	17,100 European ancestry individuals, 715 Orcadian individuals	NA	7q11.23	7	73441939	MLXIPL	BAZ1B			ENSG00000009954	NA	NA	rs2240466-G	rs2240466	0	2240466	3_prime_UTR_variant	0	0.87	1e-12	12		0.14	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	11q12.2	11	61829740	FADS2, FADS3	FADS2			ENSG00000134824	NA	NA	rs174570-G	rs174570	0	174570	intron_variant	0	0.83	4e-06	5.39794000867204		0.06	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	15q21.3	15	58391167	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs1532085-G	rs1532085	0	1532085	intron_variant	0	0.59	1e-35	35		0.13	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	18q21.1	18	49640844	LIPG	LIPG - SMUG1P1	ENSG00000101670	ENSG00000267444		41659	9506	rs4939883-G	rs4939883	0	4939883	TF_binding_site_variant	1	0.83	2e-11	10.698970004336		0.1	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	19q13.32	19	44892009	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs157580-G	rs157580	0	157580	intron_variant	0	0.33	4e-07	6.39794000867204		0.06	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	16q13	16	56971567	CETP	CETP			ENSG00000087237	NA	NA	rs1532624-C	rs1532624	0	1532624	intron_variant	0	0.57	9e-94	93.0457574905607		0.21	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	2p24.1	2	20983311	APOB	LINC02850 - AC115619.1	ENSG00000236436	ENSG00000261012		121650	16002	rs6754295-C	rs6754295	0	6754295	regulatory_region_variant	1	0.25	4e-08	7.39794000867204		0.07	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	11p11.2	11	48497341	FOLH1, MADD	OR4A46P - OR4A40P	ENSG00000255304	ENSG00000254832		61	14932	rs7395662-G	rs7395662	0	7395662	intergenic_variant	1	0.61	6e-11	10.2218487496164		0.07	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	9q31.1	9	104894789	ABCA1	ABCA1			ENSG00000165029	NA	NA	rs3905000-G	rs3905000	0	3905000	intron_variant	0	0.86	9e-13	12.0457574905607		0.11	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	8p21.3	8	20007664	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		40405	71450	rs2083637-G	rs2083637	0	2083637	intergenic_variant	1	0.26	6e-18	17.2218487496164		0.11	[NR] s.d. increase	Affymetrix, Illumina [up to 600000]	N
2009-01-12	19060911	Aulchenko YS	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060911	Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.	HDL cholesterol	20,697 European ancestry individuals, 715 Orcadian individuals	NA	16q22.1	16	67868167	CTCF, PRMT8	NUTF2			ENSG00000102898	NA	NA	rs2271293-G	rs2271293	0	2271293	intron_variant	0	0.87	8e-16	15.0969100130081		0.13	[NR] s.d. decrease	Affymetrix, Illumina [up to 600000]	N
2009-04-23	19369658	Ikram MA	2009-04-15	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19369658	Genomewide association studies of stroke.	Stroke	1,164 European ancestry ischemic cases, 380 European ancestry cases, 18,058 European ancestry controls	259 African American ancestry ischemic cases, 41 African American ancestry cases, 2,704 African American ancestry controls, 652 European ancestry ischemic cases, 3,613 European ancestry controls	12p13.33	12	674318	NINJ2, WNK1	AC021054.1 - LINC02455	ENSG00000177406	ENSG00000256672		10122	483	rs12425791-A	rs12425791	0	12425791	intergenic_variant	1	0.23	1e-09	9	(EA)	1.27	[NR]	Affymetrix, Illumina [2194468] (imputed)	N
2009-04-23	19369658	Ikram MA	2009-04-15	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19369658	Genomewide association studies of stroke.	Stroke	1,164 European ancestry ischemic cases, 380 European ancestry cases, 18,058 European ancestry controls	259 African American ancestry ischemic cases, 41 African American ancestry cases, 2,704 African American ancestry controls, 652 European ancestry ischemic cases, 3,613 European ancestry controls	12p13.33	12	674318	NINJ2, WNK1	AC021054.1 - LINC02455	ENSG00000177406	ENSG00000256672		10122	483	rs12425791-A	rs12425791	0	12425791	intergenic_variant	1	0.23	2e-09	8.69897000433602	(ischemic stroke, EA)	1.29	[NR]	Affymetrix, Illumina [2194468] (imputed)	N
2009-04-23	19369658	Ikram MA	2009-04-15	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19369658	Genomewide association studies of stroke.	Stroke	1,164 European ancestry ischemic cases, 380 European ancestry cases, 18,058 European ancestry controls	259 African American ancestry ischemic cases, 41 African American ancestry cases, 2,704 African American ancestry controls, 652 European ancestry ischemic cases, 3,613 European ancestry controls	12p13.33	12	674318	NINJ2, WNK1	AC021054.1 - LINC02455	ENSG00000177406	ENSG00000256672		10122	483	rs12425791-A	rs12425791	0	12425791	intergenic_variant	1	0.23	8e-10	9.09691001300806		1.26	[NR]	Affymetrix, Illumina [2194468] (imputed)	N
2009-04-23	19369658	Ikram MA	2009-04-15	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19369658	Genomewide association studies of stroke.	Stroke	1,164 European ancestry ischemic cases, 380 European ancestry cases, 18,058 European ancestry controls	259 African American ancestry ischemic cases, 41 African American ancestry cases, 2,704 African American ancestry controls, 652 European ancestry ischemic cases, 3,613 European ancestry controls	12p13.33	12	674318	NINJ2, WNK1	AC021054.1 - LINC02455	ENSG00000177406	ENSG00000256672		10122	483	rs12425791-A	rs12425791	0	12425791	intergenic_variant	1	0.23	1e-09	9	(ischemic stroke)	1.29	[NR]	Affymetrix, Illumina [2194468] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	1q23.3	1	162163327	NOS1AP	NOS1AP, AL450163.1			ENSG00000198929, ENSG00000285636	NA	NA	rs12029454-A	rs12029454	0	12029454	intron_variant	0	0.15	3e-45	44.5228787452803		2.98	[2.63-3.32] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	1q23.3	1	162143120	NOS1AP	NOS1AP			ENSG00000198929	NA	NA	rs16857031-G	rs16857031	0	16857031	intron_variant	0	0.14	1e-34	34		2.63	[2.28-2.97] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	3p22.2	3	38551902	SCN5A	SCN5A			ENSG00000183873	NA	NA	rs12053903-C	rs12053903	0	12053903	intron_variant	0	0.34	1e-14	14		1.23	[0.88-1.57] msec decrease	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	17q12	17	34997363	LIG3, RFFL	LIG3			ENSG00000005156	NA	NA	rs2074518-T	rs2074518	0	2074518	non_coding_transcript_exon_variant	0	0.46	6e-12	11.2218487496164		1.05	[0.71-1.39] msec decrease	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	1p36.31	1	6219310	NPHP4, CHDS, ACOT7, PLEKHG5, KLH21, RNF207	RNF207			ENSG00000158286	NA	NA	rs846111-C	rs846111	0	846111	missense_variant	0	0.28	1e-16	16		1.75	[1.41-2.09] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	11p15.5	11	2463573	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs2074238-T	rs2074238	0	2074238	intron_variant	0	0.06	3e-17	16.5228787452803		7.88	[6.16-9.59] msec decrease	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	1q23.3	1	162064100	NOS1AP	AL590408.1 - NOS1AP	ENSG00000227818	ENSG00000198929		24533	5591	rs12143842-T	rs12143842	0	12143842	intergenic_variant	1	0.26	2e-78	77.698970004336		3.15	[2.81-3.49] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	16p13.13	16	11597897	LITAF, TNFRSF17, CLEC16A, SNN, ZC3H7A	LITAF			ENSG00000189067	NA	NA	rs8049607-T	rs8049607	0	8049607	intron_variant	0	0.49	5e-15	14.301029995664		1.23	[0.88-1.57] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	16q21	16	58533334	GINS3, NDRG4, SLC38A7, GOT2, CNOT1	CNOT1			ENSG00000125107	NA	NA	rs37062-G	rs37062	0	37062	intron_variant	0	0.24	3e-25	24.5228787452803		1.75	[1.41-2.09] msec decrease	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	11p15.5	11	2481089	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs12576239-T	rs12576239	0	12576239	intron_variant	0	0.13	1e-15	15		1.75	[1.41-2.09] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	7q36.1	7	150940775	KCNH2	AOC1 - KCNH2	ENSG00000002726	ENSG00000055118		79271	4186	rs4725982-T	rs4725982	0	4725982	intergenic_variant	1	0.22	5e-16	15.301029995664		1.58	[1.23-1.92] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	7q36.1	7	150925074	KCNH2	AOC1 - KCNH2	ENSG00000002726	ENSG00000055118		63570	19887	rs2968864-C	rs2968864	0	2968864	intergenic_variant	1	0.25	8e-16	15.0969100130081		1.4	[1.06-1.74] msec decrease	Affymetrix, Illumina [up to 2543686] (imputed)	N
2009-03-31	19305408	Newton-Cheh C	2009-03-22	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19305408	Common variants at ten loci influence QT interval duration in the QTGEN Study.	QT interval	13,685 European ancestry individuals	15,854 European ancestry individuals	6q22.31	6	118672469	c6orf204, SLC35F1, PLN, ASF1A	CEP85L			ENSG00000111860	NA	NA	rs11756438-A	rs11756438	0	11756438	intron_variant	0	0.47	5e-22	21.301029995664		1.4	[1.06-1.74] msec increase	Affymetrix, Illumina [up to 2543686] (imputed)	N
2010-03-05	20159242	Li X	2010-02-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/20159242	Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.	Asthma	607 European ancestry cases, 3,294 European ancestry controls	NA	5q31.1	5	132565533	RAD50	AC116366.3, RAD50			ENSG00000283782, ENSG00000113522	NA	NA	rs2244012-C	rs2244012	0	2244012	intron_variant	0	0.21	3e-07	6.52287874528034		1.64	[1.36-1.97]	Illumina [292443]	N
2010-03-05	20159242	Li X	2010-02-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/20159242	Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.	Asthma	607 European ancestry cases, 3,294 European ancestry controls	NA	15q21.2	15	51677471	SCG3	DMXL2 - SCG3	ENSG00000104093	ENSG00000104112		54638	4021	rs17525472-?	rs17525472	0	17525472	intergenic_variant	1	NR	2e-06	5.69897000433602		NA		Illumina [292443]	N
2010-03-05	20159242	Li X	2010-02-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/20159242	Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.	Asthma	607 European ancestry cases, 3,294 European ancestry controls	NA	20p13	20	3846662	KIAA1271	AP5S1 - MAVS	ENSG00000125843	ENSG00000088888		17824	137	rs4815617-?	rs4815617	0	4815617	regulatory_region_variant	1	NR	8e-06	5.09691001300806		NA		Illumina [292443]	N
2009-01-14	19110211	Meisinger C	2008-12-24	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19110211	A genome-wide association study identifies three loci associated with mean platelet volume.	Mean platelet volume	1,606 European ancestry individuals	8,617 European ancestry individuals	17q11.2	17	29376331	TAOK1	AC068025.1, AC068025.2			ENSG00000264808, ENSG00000266111	NA	NA	rs2138852-C	rs2138852	0	2138852	intron_variant	0	0.47	7e-28	27.1549019599857		0.02	[0.01-0.02] per log fl decrease	Affymetrix [335152]	N
2009-01-14	19110211	Meisinger C	2008-12-24	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19110211	A genome-wide association study identifies three loci associated with mean platelet volume.	Mean platelet volume	1,606 European ancestry individuals	8,617 European ancestry individuals	3p14.3	3	56831748	ARHGEF3	ARHGEF3			ENSG00000163947	NA	NA	rs12485738-A	rs12485738	0	12485738	intron_variant	0	0.30	4e-27	26.397940008672		0.02	[0.01-0.02] per log fl increase	Affymetrix [335152]	N
2009-01-14	19110211	Meisinger C	2008-12-24	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19110211	A genome-wide association study identifies three loci associated with mean platelet volume.	Mean platelet volume	1,606 European ancestry individuals	8,617 European ancestry individuals	12q24.31	12	121927677	WDR66	WDR66			ENSG00000158023	NA	NA	rs7961894-A	rs7961894	0	7961894	intron_variant	0	0.11	7e-48	47.1549019599857		0.03	[0.03-0.04] per log fl increase	Affymetrix [335152]	N
2009-03-18	19249006	Xiong DH	2009-02-25	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19249006	Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups.	Bone mineral density	1,000 European ancestry individuals	4,925 European ancestry individuals, 350 Chinese ancestry hip fracture cases, 350 Chinese ancestry hip fracture controls, 2,955 Chinese ancestry individuals, 908 West African ancestry males	16q23.1	16	77395075	ADAMTS18	ADAMTS18			ENSG00000140873	NA	NA	rs16945612-?	rs16945612	0	16945612	intron_variant	0		2e-08	7.69897000433602	(hip BMD)	NA		Affymetrix [379319]	N
2009-03-18	19249006	Xiong DH	2009-02-25	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19249006	Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups.	Bone mineral density	1,000 European ancestry individuals	4,925 European ancestry individuals, 350 Chinese ancestry hip fracture cases, 350 Chinese ancestry hip fracture controls, 2,955 Chinese ancestry individuals, 908 West African ancestry males	1p22.1	1	91745463	TGFBR3	TGFBR3			ENSG00000069702	NA	NA	rs17131547-?	rs17131547	0	17131547	intron_variant	0		1e-06	6	(spine BMD)	0.4974	unit decrease	Affymetrix [379319]	N
2009-03-31	19287509	Cui J	2009-03-14	Mol Med	www.ncbi.nlm.nih.gov/pubmed/19287509	Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis.	Anti-cyclic Citrullinated Peptide Antibody	531 European ancestry cases	849 European ancestry cases	6p21.32	6	32395438	HLA-DRA, BTNL2	BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, TSBP1-AS1			ENSG00000226127, ENSG00000225412, ENSG00000204290, ENSG00000225845, ENSG00000229741, ENSG00000224770, ENSG00000229597, ENSG00000224242, ENSG00000225914	NA	NA	rs1980493-?	rs1980493	0	1980493	intron_variant	0	0.13	5e-07	6.30102999566398		NA		Affymetrix [97248]	N
2009-03-30	19278955	Tregouet DA	2009-03-10	Blood	www.ncbi.nlm.nih.gov/pubmed/19278955	Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.	Venous thromboembolism	419 European ancestry cases, 1,228 European ancestry controls	1,757 European ancestry cases, 1,480 European ancestry controls	9q34.2	9	133273813	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs505922-C	rs505922	0	505922	intron_variant	0	0.35	4e-15	14.397940008672		1.81	[1.56-2.11]	Illumina [291872]	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Systolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	17q21.31	17	45130754	ACBD4, PLCD3, HEXIM1, HEXIM2	PLCD3			ENSG00000161714	NA	NA	rs12946454-T	rs12946454	0	12946454	intron_variant	0	0.28	1e-08	8		0.57	[0.37-0.77] mm Hg increase	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Systolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	1p36.22	1	11802721	NPPA, CLCN6, NPPB, AGTRAP, MTHFR	MTHFR			ENSG00000177000	NA	NA	rs17367504-G	rs17367504	0	17367504	intron_variant	0	0.14	2e-13	12.698970004336		0.85	[0.63-1.07] mm Hg decrease	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Systolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	10q24.32	10	103086421	NT5C2, AS3MT, CNNM2, CYP17A1	CNNM2			ENSG00000148842	NA	NA	rs11191548-T	rs11191548	0	11191548	3_prime_UTR_variant	0	0.91	7e-24	23.1549019599857		1.16	[0.92-1.40] mm Hg increase	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Diastolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	4q21.21	4	80263187	FGF5, PRDM8, c4orf22	PRDM8 - FGF5	ENSG00000152784	ENSG00000138675		58858	3412	rs16998073-T	rs16998073	0	16998073	intergenic_variant	1	0.21	1e-21	21		0.5	[0.40-0.60] mm Hg increase	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Diastolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	10q21.2	10	61764833	c10orf107, RHOBTB1, ARID5B, TMEM26, RTKN2	CABCOCO1			ENSG00000183346	NA	NA	rs1530440-T	rs1530440	0	1530440	intron_variant	0	0.19	1e-09	9		0.39	[0.27-0.51] mm Hg decrease	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Diastolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	15q24.1	15	74785026	CYP1A1, CYP1A2, LMAN1L, CPLX3, CSK, ARID3B	CSK			ENSG00000103653	NA	NA	rs1378942-C	rs1378942	0	1378942	intron_variant	0	0.36	1e-23	23		0.43	[0.35-0.51] mm Hg increase	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Diastolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	12q24.12	12	111569952	SH2B3, ATXN2	ATXN2			ENSG00000204842	NA	NA	rs653178-T	rs653178	0	653178	intron_variant	0	0.53	3e-18	17.5228787452803		0.46	[0.36-0.56] mm Hg decrease	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Diastolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	3q26.2	3	169448100	MDS1	AC074033.1, MECOM			ENSG00000241479, ENSG00000085276	NA	NA	rs1918974-T	rs1918974	0	1918974	intron_variant	0	0.54	8e-08	7.09691001300806		0.27	[0.17-0.37] mm Hg decrease	Affymetrix, Illumina [2497993] (imputed)	N
2009-05-19	19430483	Newton-Cheh C	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Diastolic blood pressure	34,433 European ancestry individuals	Up to 100,347 European ancestry individuals, up to 12,889 Indian Asian ancestry individuals	17q21.33	17	49363104	PHB, ZNF652	AC091180.2			ENSG00000248714	NA	NA	rs16948048-G	rs16948048	0	16948048	intron_variant	0	0.39	5e-09	8.30102999566398		0.31	[0.21-0.41] mm Hg increase	Affymetrix, Illumina [2497993] (imputed)	N
2011-01-14	20801717	Shatunov A	2010-10-01	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/20801717	Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.	Amyotrophic lateral sclerosis	4,857 European ancestry cases, 8,987 European ancestry controls	NA	18q23	18	79813548	NR	AC021594.2			ENSG00000267780	NA	NA	rs4799088-?	rs4799088	0	4799088	intron_variant	0	NR	9e-06	5.04575749056067		1.15	[NR]	Illumina [227475]	N
2011-01-14	20801717	Shatunov A	2010-10-01	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/20801717	Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.	Amyotrophic lateral sclerosis	4,857 European ancestry cases, 8,987 European ancestry controls	NA	11q14.3	11	89611857	NR	AP003400.1 - FOLH1B	ENSG00000255429	ENSG00000134612		22246	27380	rs1488902-C	rs1488902	0	1488902	regulatory_region_variant	1	NR	3e-06	5.52287874528034		1.145	[NR]	Illumina [227475]	N
2011-01-14	20801717	Shatunov A	2010-10-01	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/20801717	Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.	Amyotrophic lateral sclerosis	4,857 European ancestry cases, 8,987 European ancestry controls	NA	9p21.2	9;9	27556782;27543283	intergenic	C9orf72; AL451123.1; C9orf72				NA	NA	rs10122902-G; rs3849942-G	rs10122902; rs3849942	0	NA	synonymous_variant; non_coding_transcript_exon_variant	NA	0.57	5e-11	10.301029995664		NA		Illumina [227475]	N
2011-01-14	20801717	Shatunov A	2010-10-01	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/20801717	Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study.	Amyotrophic lateral sclerosis	4,857 European ancestry cases, 8,987 European ancestry controls	NA	9p21.2	9;9	27556782;27543283	intergenic	C9orf72; AL451123.1; C9orf72				NA	NA	rs10122902-G; rs3849942-A	rs10122902; rs3849942	0	NA	synonymous_variant; non_coding_transcript_exon_variant	NA	0.23	8e-10	9.09691001300806		NA		Illumina [227475]	N
2009-01-21	19124843	Ober C	2009-01-07	J Lipid Res	www.ncbi.nlm.nih.gov/pubmed/19124843	Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.	Lp (a) levels	357 Hutterite individuals	1,054 European ancestry males	6q25.3	6	160539327	LPA	LPA			ENSG00000198670	NA	NA	rs6919346-?	rs6919346	0	6919346	intron_variant	0	0.16	4e-11	10.397940008672		0.66	[NR] mg/dl decrease	Affymetrix [290327]	N
2009-05-05	19359809	Hiura Y	2009-04-10	Circ J	www.ncbi.nlm.nih.gov/pubmed/19359809	Identification of genetic markers associated with high-density lipoprotein-cholesterol by genome-wide screening in a Japanese population: the Suita study.	HDL cholesterol	900 Japanese ancestry individuals	1,810 Japanese ancestry individuals	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	1	0.20	3e-12	11.5228787452803		6.2	mg/dl increase	Illumina [368274]	N
2008-08-11	18677311	O'Donovan MC	2008-07-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18677311	Identification of loci associated with schizophrenia by genome-wide association and follow-up.	Schizophrenia	479 European ancestry cases, 2,937 European ancestry controls	4,143 European ancestry cases, 6,515 European ancestry controls, 1,782 East Asian ancestry cases, 1,865 East Asian ancestry controls, 741 cases, 1,517 controls	16p13.12	16	12967754	intergenic	SHISA9			ENSG00000237515	NA	NA	rs7192086-T	rs7192086	0	7192086	intron_variant	0	0.24	6e-06	5.22184874961636		1.12	[NR]	Affymetrix [362532]	N
2008-08-11	18677311	O'Donovan MC	2008-07-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18677311	Identification of loci associated with schizophrenia by genome-wide association and follow-up.	Schizophrenia	479 European ancestry cases, 2,937 European ancestry controls	4,143 European ancestry cases, 6,515 European ancestry controls, 1,782 East Asian ancestry cases, 1,865 East Asian ancestry controls, 741 cases, 1,517 controls	11p14.1	11	29140589	intergenic	LINC02742 - AC090791.1	ENSG00000249867	ENSG00000254526		76267	19367	rs1602565-C	rs1602565	0	1602565	intergenic_variant	1	0.11	3e-06	5.52287874528034		1.16	[NR]	Affymetrix [362532]	N
2008-08-11	18677311	O'Donovan MC	2008-07-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18677311	Identification of loci associated with schizophrenia by genome-wide association and follow-up.	Schizophrenia	479 European ancestry cases, 2,937 European ancestry controls	4,143 European ancestry cases, 6,515 European ancestry controls, 1,782 East Asian ancestry cases, 1,865 East Asian ancestry controls, 741 cases, 1,517 controls	2q32.1	2	184913701	ZNF804A	ZNF804A			ENSG00000170396	NA	NA	rs1344706-T	rs1344706	0	1344706	intron_variant	0	0.59	2e-07	6.69897000433602		1.12	[NR]	Affymetrix [362532]	N
2008-06-18	18488026	Brown KM	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488026	Common sequence variants on 20q11.22 confer melanoma susceptibility.	Melanoma	864 European ancestry cases, 864 European ancestry controls	1,230 European ancestry cases, 1,251 European ancestry controls	20q11.22	20	34583968	CDC91L1	PIGU			ENSG00000101464	NA	NA	rs910873-T	rs910873	0	910873	intron_variant	0	0.09	1e-15	15		1.75	[1.53-2.01]	Illumina [535150]	N
2008-06-10	18455228	Richards JB	2008-04-29	Lancet	www.ncbi.nlm.nih.gov/pubmed/18455228	Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.	Bone mineral density	2,094 European ancestry female individuals	6,463 European ancestry individuals	8q24.12	8	118911634	TNFRSF11B	SAMD12-AS1 - TNFRSF11B	ENSG00000281641	ENSG00000164761		5479	11923	rs4355801-A	rs4355801	0	4355801	regulatory_region_variant	1	0.53	8e-10	9.09691001300806		0.09	[NR] SD decrease	Illumina [314075]	N
2008-06-10	18455228	Richards JB	2008-04-29	Lancet	www.ncbi.nlm.nih.gov/pubmed/18455228	Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study.	Bone mineral density	2,094 European ancestry female individuals	6,463 European ancestry individuals	11q13.2	11	68433827	LRP5	LRP5			ENSG00000162337	NA	NA	rs3736228-T	rs3736228	0	3736228	missense_variant	0	0.14	6e-12	11.2218487496164		0.13	[NR] SD decrease	Illumina [314075]	N
2008-09-08	18439552	Reiner AP	2008-04-24	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18439552	Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.	C-reactive protein	909 European ancestry individuals	5,106 European ancestry individuals	1q23.2	1	159730249	CRP	CRP - AL445528.1	ENSG00000132693	ENSG00000235226		15660	28921	rs11265260-?	rs11265260	0	11265260	intergenic_variant	1	NR	7e-06	5.15490195998574		NA		Illumina [317000]	N
2008-09-08	18439552	Reiner AP	2008-04-24	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18439552	Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.	C-reactive protein	909 European ancestry individuals	5,106 European ancestry individuals	19q13.32	19	44892362	APOE	TOMM40			ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	0	NR	1e-07	7		NA		Illumina [317000]	N
2008-09-08	18439552	Reiner AP	2008-04-24	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18439552	Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.	C-reactive protein	909 European ancestry individuals	5,106 European ancestry individuals	12q24.31	12	121001630	HNF1A	C12orf43, HNF1A			ENSG00000157895, ENSG00000135100	NA	NA	rs1169310-A	rs1169310	0	1169310	3_prime_UTR_variant	0	0.38	2e-08	7.69897000433602		0.13	[0.08-0.17] mg/l decrease in log(CRP) level	Illumina [317000]	N
2011-05-02	21460842	Cha PC	2011-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21460842	A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.	Uterine fibroids	1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls	3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls	10q24.33	10	103954641	OBFC1, SLK	STN1 - SLK	ENSG00000107960	ENSG00000065613		36457	12499	rs7913069-A	rs7913069	0	7913069	intergenic_variant	1	0.07	9e-14	13.0457574905607		1.47	[1.23-1.75]	Illumina [457044]	N
2011-05-02	21460842	Cha PC	2011-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21460842	A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.	Uterine fibroids	1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls	3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls	22q13.1	22	40256869	TNRC6B	TNRC6B			ENSG00000100354	NA	NA	rs12484776-G	rs12484776	0	12484776	intron_variant	0	0.36	3e-12	11.5228787452803		1.23	[1.11-1.37]	Illumina [457044]	N
2011-05-02	21460842	Cha PC	2011-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21460842	A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.	Uterine fibroids	1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls	3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls	11p15.5	11	203788	ODF3, RIC8A, SIRT3, BET1L	AC069287.2, BET1L			ENSG00000254559, ENSG00000177951	NA	NA	rs2280543-G	rs2280543	0	2280543	3_prime_UTR_variant	0	0.88	4e-12	11.397940008672		1.39	[1.17-1.64]	Illumina [457044]	N
2011-05-02	21460842	Cha PC	2011-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21460842	A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.	Uterine fibroids	1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls	3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls	2p16.1	2	59055456	NR	LINC01122, AC007092.1			ENSG00000233723, ENSG00000285673	NA	NA	rs991964-A	rs991964	0	991964	intron_variant	0	0.34	9e-06	5.04575749056067		1.15	[1.03-1.28]	Illumina [457044]	N
2011-05-02	21460842	Cha PC	2011-04-03	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21460842	A genome-wide association study identifies three loci associated with susceptibility to uterine fibroids.	Uterine fibroids	1,607 Japanese ancestry cases, 1,428 Japanese ancestry controls	3,439 Japanese ancestry cases, 3,244 Japanese ancestry controls	12q23.2	12	102731912	NR	AC010202.1 - LINC00485	ENSG00000257254	ENSG00000258169		218257	77368	rs2172873-A	rs2172873	0	2172873	intergenic_variant	1	0.22	2e-06	5.69897000433602		1.18	[1.04-1.34]	Illumina [457044]	N
2009-04-10	18711366	Unoki H	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711366	SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.	Type 2 diabetes	194 Japanese ancestry cases, 1,558 Japanese ancestry controls	5,324 East Asian ancestry cases, 7,037 East Asian ancestry controls, 4,085 European ancestry cases, 5,302 European ancestry controls	11p15.4	11	2837316	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs2237897-C	rs2237897	0	2237897	intron_variant	0	0.34	1e-16	16		1.33	[1.24-1.41]	Affymetrix [207097]	N
2009-04-10	18711366	Unoki H	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711366	SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.	Type 2 diabetes	194 Japanese ancestry cases, 1,558 Japanese ancestry controls	5,324 East Asian ancestry cases, 7,037 East Asian ancestry controls, 4,085 European ancestry cases, 5,302 European ancestry controls	6p22.3	6	20657634	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs4712524-G	rs4712524	0	4712524	intron_variant	0	0.42	3e-10	9.52287874528034		1.22	[1.15-1.31]	Affymetrix [207097]	N
2009-04-10	18711366	Unoki H	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711366	SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.	Type 2 diabetes	194 Japanese ancestry cases, 1,558 Japanese ancestry controls	5,324 East Asian ancestry cases, 7,037 East Asian ancestry controls, 4,085 European ancestry cases, 5,302 European ancestry controls	3q27.2	3	185812502	IGF2BP2	IGF2BP2			ENSG00000073792	NA	NA	rs6769511-C	rs6769511	0	6769511	intron_variant	0	0.32	1e-09	9		1.23	[1.15-1.31]	Affymetrix [207097]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	16p13.11	16	15038117	PDXDC1, NTAN1	PDXDC1, NTAN1, NTAN1			ENSG00000179889, ENSG00000275779, ENSG00000157045	NA	NA	rs1136001-T	rs1136001	0	1136001	missense_variant	0	0.44	7e-06	5.15490195998574		0.05	[0.03-0.07] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	16q23.3	16	83605730	CDH13	CDH13			ENSG00000140945	NA	NA	rs6563943-A	rs6563943	0	6563943	intron_variant	0	0.32	6e-06	5.22184874961636		0.05	[0.03-0.07] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	13q31.3	13	91363723	GPC5	MIR17HG - GPC5	ENSG00000215417	ENSG00000179399		9144	34898	rs8002779-A	rs8002779	0	8002779	intergenic_variant	1	0.48	3e-06	5.52287874528034		0.05	[0.03-0.07] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	2p16.1	2	55869757	EFEMP1	EFEMP1			ENSG00000115380	NA	NA	rs3791679-A	rs3791679	0	3791679	intron_variant	0	0.25	6e-09	8.22184874961636		0.07	[0.05-0.09] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	2p22.3	2	33246125	LTBP1	LTBP1			ENSG00000049323	NA	NA	rs3769528-G	rs3769528	0	3769528	intron_variant	0	0.15	8e-08	7.09691001300806		0.08	[0.05-0.11] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	15q25.2	15	83913372	ADAMTSL3	ADAMTSL3			ENSG00000156218	NA	NA	rs4842838-G	rs4842838	0	4842838	missense_variant	0	0.29	1e-07	7		0.06	[0.04-0.08] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	1p36.13	1	17005181	ATP13A2, SDHB	ATP13A2			ENSG00000159363	NA	NA	rs3738814-A	rs3738814	0	3738814	intron_variant	0	0.35	2e-07	6.69897000433602		0.06	[0.04-0.08] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	15q21.2	15	51277213	CYP19A1	CYP19A1, MIR4713HG			ENSG00000137869, ENSG00000259240	NA	NA	rs2305707-G	rs2305707	0	2305707	non_coding_transcript_exon_variant	0	0.37	7e-07	6.15490195998574		0.06	[0.04-0.07] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	12q13.13	12	53647408	ATF7, ATP5G2	ATP5MC2			ENSG00000135390	NA	NA	rs11170631-C	rs11170631	0	11170631	intron_variant	0	0.36	9e-07	6.04575749056067		0.05	[0.03-0.07] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	10q26.13	10	122406099	PLEKHA1	PLEKHA1			ENSG00000107679	NA	NA	rs6585827-G	rs6585827	0	6585827	intron_variant	0	0.43	2e-06	5.69897000433602		0.05	[0.03-0.07] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	2q35	2	219084462	IHH	AC068946.1, NHEJ1			ENSG00000280537, ENSG00000187736	NA	NA	rs16859517-T	rs16859517	0	16859517	intron_variant	0	0.39	5e-06	5.30102999566398		0.05	[0.03-0.07] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	7p15.3	7	21984422	CDCA7L	CDCA7L - RAPGEF5	ENSG00000164649	ENSG00000136237		38519	133814	rs1175000-C	rs1175000	0	1175000	intergenic_variant	1	0.40	5e-06	5.30102999566398		0.05	[0.03-0.07] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	13q14.11	13	42057583	DGKH	DGKH			ENSG00000102780	NA	NA	rs6561030-A	rs6561030	0	6561030	intron_variant	0	0.28	7e-06	5.15490195998574		0.05	[0.03-0.07] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	1q25.3	1	184033740	GLT25D2	COLGALT2			ENSG00000198756	NA	NA	rs756199-G	rs756199	0	756199	intron_variant	0	0.42	7e-06	5.15490195998574		0.05	[0.03-0.07] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	9q34.3	9	136229894	QSOX2, LHX3	QSOX2			ENSG00000165661	NA	NA	rs12338076-C	rs12338076	0	12338076	intron_variant	0	0.34	2e-08	7.69897000433602		0.06	[0.04-0.08] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	15q24.2	15	75463126	SIN3A, PTPN9	SIN3A - PTPN9	ENSG00000169375	ENSG00000169410		7284	125	rs4886707-T	rs4886707	0	4886707	regulatory_region_variant	1	0.42	8e-08	7.09691001300806		0.06	[0.04-0.08] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	6p21.31	6	34197944	HMGA1	KRT18P9 - CYCSP55	ENSG00000271231	ENSG00000214810		6865	21495	rs7742369-G	rs7742369	0	7742369	TF_binding_site_variant	1	0.14	1e-13	13		0.11	[0.08-0.14] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	8q12.1	8	56187590	PLAG1	PLAG1			ENSG00000181690	NA	NA	rs7833986-A	rs7833986	0	7833986	intron_variant	0	0.08	8e-10	9.09691001300806		0.12	[0.08-0.16] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	3q23	3	141418193	ZBTB38	ZBTB38			ENSG00000177311	NA	NA	rs9825379-A	rs9825379	0	9825379	intron_variant	0	0.24	6e-09	8.22184874961636		0.07	[0.05-0.09] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	2q37.1	2	232212354	DIS3L2	DIS3L2			ENSG00000144535	NA	NA	rs7571816-A	rs7571816	0	7571816	intron_variant	0	0.45	9e-09	8.04575749056067		0.06	[0.04-0.08] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	12q23.2	12	102405820	IGF1	LINC02456, IGF1			ENSG00000283052, ENSG00000017427	NA	NA	rs5742692-G	rs5742692	0	5742692	intron_variant	0	0.27	4e-08	7.39794000867204		0.07	[0.05-0.09] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	18q11.2	18	23155444	CABLES1	CABLES1			ENSG00000134508	NA	NA	rs4369779-T	rs4369779	0	4369779	intron_variant	0	0.20	3e-06	5.52287874528034		0.06	[0.04-0.08] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	7p22.3	7	2756323	GNA12	AMZ1, GNA12			ENSG00000174945, ENSG00000146535	NA	NA	rs798497-G	rs798497	0	798497	intron_variant	0	0.27	7e-07	6.15490195998574		0.06	[0.04-0.08] cm decrease	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	20q11.22	20	35509524	UQCC, GDF5	CEP250			ENSG00000126001	NA	NA	rs2236164-C	rs2236164	0	2236164	intron_variant	0	0.22	2e-06	5.69897000433602		0.06	[0.04-0.08] cm increase	Illumina [420885]	N
2010-03-25	20189936	Okada Y	2010-02-26	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20189936	A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.	Height	19,633 Japanese ancestry individuals	NA	4p15.31	4	17796343	LCORL, NCAPG	FAM184B - DCAF16	ENSG00000047662	ENSG00000163257		14722	4312	rs7678436-A	rs7678436	0	7678436	intergenic_variant	1	0.26	8e-15	14.0969100130081		0.09	[0.07-0.11] cm decrease	Illumina [420885]	N
2008-06-16	17653210	Maeda S	2007-08-01	Kidney Int Suppl	www.ncbi.nlm.nih.gov/pubmed/17653210	Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.	Type 2 diabetes nephropathy	94 Japanese ancestry cases, 94 Japanese ancestry controls	NA	7p14.2	7	36878390	ELMO1	ELMO1			ENSG00000155849	NA	NA	rs741301-?	rs741301	0	741301	intron_variant	0	NR	8e-06	5.09691001300806		2.67	[1.71-4.16]	NR [~ 80000]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	2q24.2	2	160060986	LY75, ITGB6, PLA2R1, RBMS1	PLA2R1			ENSG00000153246	NA	NA	rs4664308-A	rs4664308	0	4664308	intron_variant	0	0.43	9e-29	28.0457574905607		2.28	[1.96-2.64]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32638107	HLA-DQA1	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs2187668-A	rs2187668	0	2187668	intron_variant	0	0.1297	8e-93	92.0969100130081		4.32	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31344549	intergenic	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs3134792-C	rs3134792	0	3134792	intron_variant	0	0.114	6e-72	71.2218487496164		3.93	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32293475	c6orf10	TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1-AS1			ENSG00000234280, ENSG00000232106, ENSG00000206245, ENSG00000204296, ENSG00000206310, ENSG00000226892, ENSG00000237881, ENSG00000236672, ENSG00000225914	NA	NA	rs7775397-G	rs7775397	0	7775397	missense_variant	0	0.1139	5e-71	70.301029995664		3.83	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31973120	intergenic	STK19			ENSG00000234947	NA	NA	rs389884-C	rs389884	0	389884	non_coding_transcript_exon_variant	0	0.1148	8e-66	65.0969100130081		3.65	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31161533	TCF19	TCF19, TCF19, TCF19, TCF19, TCF19, TCF19, TCF19			ENSG00000224941, ENSG00000224379, ENSG00000206455, ENSG00000137310, ENSG00000234674, ENSG00000233890, ENSG00000224472	NA	NA	rs7750641-T	rs7750641	0	7750641	missense_variant	0	0.1263	3e-58	57.5228787452803		3.35	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31090563	intergenic	RNU6-1133P - C6orf15	ENSG00000222895	ENSG00000229432		7454	20660	rs3130544-A	rs3130544	0	3130544	intergenic_variant	1	0.1238	9e-58	57.0457574905607		3.34	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31634066	BAT2	PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A			ENSG00000231825, ENSG00000204469, ENSG00000231370, ENSG00000206427, ENSG00000226618, ENSG00000225748, ENSG00000225164	NA	NA	rs3115663-G	rs3115663	0	3115663	non_coding_transcript_exon_variant	0	0.1812	7e-57	56.1549019599857		3.04	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31635993	BAT2	PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A			ENSG00000231825, ENSG00000204469, ENSG00000231370, ENSG00000206427, ENSG00000226618, ENSG00000225748, ENSG00000225164	NA	NA	rs9267522-G	rs9267522	1	11229	synonymous_variant	0	0.1811	1e-56	56		3.04	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31664357	BAT4	GPANK1, GPANK1, GPANK1, GPANK1, GPANK1			ENSG00000204438, ENSG00000228605, ENSG00000232312, ENSG00000233210, ENSG00000236011	NA	NA	rs3130618-A	rs3130618	0	3130618	missense_variant	0	0.1811	2e-56	55.698970004336		3.03	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32395438	BTNL2	BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, TSBP1-AS1			ENSG00000226127, ENSG00000225412, ENSG00000204290, ENSG00000225845, ENSG00000229741, ENSG00000224770, ENSG00000229597, ENSG00000224242, ENSG00000225914	NA	NA	rs1980493-G	rs1980493	0	1980493	intron_variant	0	0.1656	1e-48	48		2.87	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31113428	intergenic	C6orf15 - PSORS1C1	ENSG00000229432	ENSG00000235487		853	1322	rs2233956-G	rs2233956	0	2233956	intergenic_variant	1	0.1813	6e-48	47.2218487496164		2.77	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31883457	EHMT2	EHMT2-AS1, EHMT2, EHMT2, EHMT2, EHMT2, EHMT2, EHMT2			ENSG00000237080, ENSG00000236759, ENSG00000206376, ENSG00000227333, ENSG00000224143, ENSG00000204371, ENSG00000238134	NA	NA	rs652888-C	rs652888	0	652888	non_coding_transcript_exon_variant	0	0.2021	3e-46	45.5228787452803		2.71	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31133897	PSORS1C1	PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1			ENSG00000231094, ENSG00000233439, ENSG00000206458, ENSG00000233734, ENSG00000204540, ENSG00000235487	NA	NA	rs3130564-T	rs3130564	0	3130564	intron_variant	0	0.1934	1e-42	42		2.62	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32166733	EGFL8	EGFL8, EGFL8, EGFL8, EGFL8, EGFL8, EGFL8, EGFL8, PPT2-EGFL8			ENSG00000241404, ENSG00000239974, ENSG00000240389, ENSG00000242038, ENSG00000243897, ENSG00000240592, ENSG00000244444, ENSG00000258388	NA	NA	rs3096697-T	rs3096697	0	3096697	missense_variant	0	0.2054	1e-41	41		2.58	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32178715	RNF5	RNF5, RNF5, RNF5, RNF5, RNF5, RNF5, RNF5			ENSG00000228405, ENSG00000228907, ENSG00000223767, ENSG00000183574, ENSG00000227277, ENSG00000204308, ENSG00000225452	NA	NA	rs3134945-T	rs3134945	0	3134945	intron_variant	0	0.2049	2e-40	39.698970004336		2.54	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32368989	c6orf10	TSBP1-AS1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1			ENSG00000225914, ENSG00000234280, ENSG00000232106, ENSG00000206245, ENSG00000204296, ENSG00000206310, ENSG00000226892, ENSG00000237881, ENSG00000236672	NA	NA	rs3129939-G	rs3129939	0	3129939	intron_variant	0	0.1772	2e-40	39.698970004336		2.6	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	30952347	DPCR1	HCG21, HCG21, HCG21, HCG21, HCG21, MUCL3, MUCL3, MUCL3, MUCL3, MUCL3, SFTA2, SFTA2, SFTA2, SFTA2, SFTA2, SFTA2			ENSG00000228448, ENSG00000233529, ENSG00000223454, ENSG00000235747, ENSG00000230541, ENSG00000168631, ENSG00000232308, ENSG00000229284, ENSG00000257232, ENSG00000232251, ENSG00000225454, ENSG00000196260, ENSG00000224246, ENSG00000230072, ENSG00000237814, ENSG00000206465	NA	NA	rs3132580-T	rs3132580	0	3132580	missense_variant	0	0.1379	3e-40	39.5228787452803		2.74	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32142202	intergenic	FKBPL - PRRT1	ENSG00000230907	ENSG00000227122		11914	6157	rs204999-G	rs204999	0	204999	intergenic_variant	1	0.2643	9e-40	39.0457574905607		2.44	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.32	6	32945469	intergenic	AL645941.2			ENSG00000248993	NA	NA	rs1480380-T	rs1480380	0	1480380	intron_variant	0	0.0877	4e-39	38.397940008672		3.05	[NR]	Illumina [242824]	N
2015-05-29	21323541	Stanescu HC	2011-02-22	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21323541	Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.	Idiopathic membranous nephropathy	556 European ancestry cases, 2,338 European ancestry controls	NA	6p21.33	6	31172270	intergenic	POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1			ENSG00000204531, ENSG00000233911, ENSG00000229094, ENSG00000230336, ENSG00000206454, ENSG00000237582, ENSG00000235068	NA	NA	rs1265159-T	rs1265159	0	1265159	intron_variant	0	0.2191	4e-37	36.397940008672		2.42	[NR]	Illumina [242824]	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	1p34.3	1	36696751	GRIK3	FTLP18 - AL596257.1	ENSG00000230214	ENSG00000284705		65894	7202	rs589249-G	rs589249	0	589249	intergenic_variant	1	0.64	3e-07	6.52287874528034		1.2	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	6p21.32	6	32203298	NOTCH4	NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4			ENSG00000235396, ENSG00000223355, ENSG00000204301, ENSG00000232339, ENSG00000234876, ENSG00000206312, ENSG00000238196	NA	NA	rs3132935-?	rs3132935	0	3132935	non_coding_transcript_exon_variant	0	0.82	5e-07	6.30102999566398	(EA)	1.25	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	6q22.31	6	124021518	NKAIN2	NKAIN2			ENSG00000188580	NA	NA	rs6917824-G	rs6917824	0	6917824	intron_variant	0	0.83	4e-06	5.39794000867204	(EA)	1.3	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	18q21.2	18	55282426	TCF4	TCF4			ENSG00000196628	NA	NA	rs1261117-T	rs1261117	0	1261117	intron_variant	0	0.06	3e-10	9.52287874528034	(EA)	1.6	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	19q13.2	19	39738769	LGALS17A, CLC	CLC - LEUTX	ENSG00000105205	ENSG00000280774		740	37826	rs12611334-G	rs12611334	0	12611334	regulatory_region_variant	1	0.70	2e-06	5.69897000433602	(EA)	1.4	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	11q24.2	11	125443703	FEZ1	FEZ1			ENSG00000149557	NA	NA	rs7930295-G	rs7930295	0	7930295	3_prime_UTR_variant	0	0.86	3e-06	5.52287874528034	(EA)	1.3	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	6p21.33	6	31635190	PRRC2A, BAG6	PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A, PRRC2A			ENSG00000231825, ENSG00000204469, ENSG00000231370, ENSG00000206427, ENSG00000226618, ENSG00000225748, ENSG00000225164	NA	NA	rs1046089-G	rs1046089	0	1046089	missense_variant	0	0.34	4e-06	5.39794000867204	(EA)	1.3	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	6p21.32	6	32203298	NOTCH4	NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4			ENSG00000235396, ENSG00000223355, ENSG00000204301, ENSG00000232339, ENSG00000234876, ENSG00000206312, ENSG00000238196	NA	NA	rs3132935-?	rs3132935	0	3132935	non_coding_transcript_exon_variant	0	0.82	3e-07	6.52287874528034		1.25	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	10q24.32	10	102902701	NT5C2, AS3MT, CNNM2	AL356608.3			ENSG00000286575	NA	NA	rs7897654-T	rs7897654	0	7897654	intron_variant	0	0.30	3e-07	6.52287874528034		1.2	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	22q13.33	22	49824963	BRD1	BRD1			ENSG00000100425	NA	NA	rs138880-C	rs138880	0	138880	intron_variant	0	0.78	2e-07	6.69897000433602		1.1	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	1q25.2	1	177753772	SEC16B	AL136114.1			ENSG00000227579	NA	NA	rs12140439-C	rs12140439	0	12140439	intron_variant	0	0.31	1e-06	6	(EA)	1.3	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	2p16.3	2	47820196	FBXO11	FBXO11			ENSG00000138081	NA	NA	rs4381823-?	rs4381823	0	4381823	intron_variant	0	0.93	6e-06	5.22184874961636	(EA)	1.43	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	3q13.33	3	119365484	ARHGAP31	ARHGAP31			ENSG00000031081	NA	NA	rs17203055-?	rs17203055	0	17203055	intron_variant	0	0.87	5e-06	5.30102999566398	(EA)	1.43	[NR]	NR [1085772] (imputed)	N
2013-05-08	23894747	Aberg KA	2013-02-01	JAMA Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23894747	A comprehensive family-based replication study of schizophrenia genes.	Schizophrenia	11,185 European ancestry cases, 10,768 European ancestry controls	1,262 African American ancestry individuals, 2,740 European ancestry individuals, 2,296 Asian ancestry individuals	6p22.1	6	27310241	POM121L2	POM121L2			ENSG00000158553	NA	NA	rs16897515-C	rs16897515	0	16897515	missense_variant	0	0.16	4e-07	6.39794000867204	(EA)	1.3	[NR]	NR [1085772] (imputed)	N
2011-01-18	21151130	Painter JN	2010-12-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21151130	Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis.	Endometriosis	3,194 European ancestry cases, 7,060 European ancestry controls	2,392 European ancestry cases, 2,271 European ancestry controls	1p31.1	1	79777316	intergenic	ADH5P2 - AC099671.1	ENSG00000232676	ENSG00000285409		255113	190417	rs12024204-G	rs12024204	0	12024204	intergenic_variant	1	0.52	6e-06	5.22184874961636		1.22	[1.07-1.18]	Illumina [504723]	N
2011-01-18	21151130	Painter JN	2010-12-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21151130	Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis.	Endometriosis	3,194 European ancestry cases, 7,060 European ancestry controls	2,392 European ancestry cases, 2,271 European ancestry controls	8p23.1	8	6971563	intergenic	DEFA10P - DEFA1	ENSG00000233531	ENSG00000284983		2450	6086	rs2738113-G	rs2738113	0	2738113	intergenic_variant	1	0.44	3e-07	6.52287874528034		1.15	[1.09-1.22]	Illumina [504723]	N
2011-01-18	21151130	Painter JN	2010-12-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21151130	Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis.	Endometriosis	3,194 European ancestry cases, 7,060 European ancestry controls	2,392 European ancestry cases, 2,271 European ancestry controls	7p15.2	7	25862019	intergenic	AC018706.1 - AC010719.1	ENSG00000286725	ENSG00000270933		30110	86638	rs12700667-A	rs12700667	0	12700667	intergenic_variant	1	0.74	1e-09	9		1.2	[1.13-1.27]	Illumina [504723]	N
2011-04-29	21460395	Gu J	2011-04-02	Cancer Prev Res (Phila)	www.ncbi.nlm.nih.gov/pubmed/21460395	A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.	Telomere length	459 individuals	1,160 individuals	1p34.2	1	43179740	WDR65	EBNA1BP2, CFAP57			ENSG00000117395, ENSG00000243710	NA	NA	rs621559-?	rs621559	0	621559	intron_variant	0	NR	2e-06	5.69897000433602		0.16	[NR] unit increase	Illumina [312531]	N
2011-04-29	21460395	Gu J	2011-04-02	Cancer Prev Res (Phila)	www.ncbi.nlm.nih.gov/pubmed/21460395	A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.	Telomere length	459 individuals	1,160 individuals	14q22.3	14	56058851	PELI2	AL163952.1 - AL138995.1	ENSG00000259868	ENSG00000277763		95881	58465	rs398652-?	rs398652	0	398652	intergenic_variant	1	NR	2e-06	5.69897000433602		0.12	[NR] unit increase	Illumina [312531]	N
2011-04-29	21460395	Gu J	2011-04-02	Cancer Prev Res (Phila)	www.ncbi.nlm.nih.gov/pubmed/21460395	A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.	Telomere length	459 individuals	1,160 individuals	6q22.1	6	116765215	KPNA5	FAM162B			ENSG00000183807	NA	NA	rs654128-?	rs654128	0	654128	missense_variant	0	NR	3e-06	5.52287874528034		0.12	[NR] unit increase	Illumina [312531]	N
2011-04-29	21460395	Gu J	2011-04-02	Cancer Prev Res (Phila)	www.ncbi.nlm.nih.gov/pubmed/21460395	A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer.	Telomere length	459 individuals	1,160 individuals	20q12	20	39500359	DHX35	RN7SL680P - AL132981.1	ENSG00000275337	ENSG00000286083		150967	154966	rs6028466-?	rs6028466	0	6028466	intergenic_variant	1	NR	3e-07	6.52287874528034		0.19	[NR] unit increase	Illumina [312531]	N
2011-05-11	21499248	Kumar V	2011-04-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21499248	Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.	Hepatocellular carcinoma	721 Japanese ancestry cases, 2,890 Japanese ancestry controls	673 Japanese ancestry cases, 2,596 Japanese ancestry controls	6p21.33	6	31398818	MICA	AL645933.2 - MICA	ENSG00000272221	ENSG00000235233		3323	966	rs2596542-A	rs2596542	0	2596542	regulatory_region_variant	1	0.33	4e-13	12.397940008672		1.39	[1.27-1.52]	Illumina [432703]	N
2011-05-11	21499248	Kumar V	2011-04-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21499248	Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.	Hepatocellular carcinoma	721 Japanese ancestry cases, 2,890 Japanese ancestry controls	673 Japanese ancestry cases, 2,596 Japanese ancestry controls	6p21.32	6	32711222	HLA-DQ, HLA-DR	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		4267	6783	rs9275572-A	rs9275572	0	9275572	intergenic_variant	1	0.36	6e-09	8.22184874961636		1.3	[1.19-1.42]	Illumina [432703]	N
2008-06-27	18488028	Sulem P	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488028	Two newly identified genetic determinants of pigmentation in Europeans.	Blue vs. green eyes	5,130 Icelandic individuals	3,330 European ancestry individuals	9p23	9	12672097	TYRP1	RNU2-47P - TYRP1	ENSG00000222581	ENSG00000107165		371646	13342	rs1408799-C	rs1408799	0	1408799	intergenic_variant	1	0.75	6e-17	16.2218487496164		1.4	[1.25-1.57]	Illumina [316515]	N
2008-06-27	18488028	Sulem P	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488028	Two newly identified genetic determinants of pigmentation in Europeans.	Burning and freckling	5,130 Icelandic individuals	3,330 European ancestry individuals	20q11.22	20;20	34150806;34141638	ASIP	AL031668.2 - ASIP; AL031668.2 - ASIP				NA	NA	rs1015362-G; rs4911414-T	rs1015362; rs4911414	0	NA	regulatory_region_variant; regulatory_region_variant	NA	0.08	6e-37	36.2218487496164		2.56	[2.06-3.18]	Illumina [316515]	N
2008-07-01	18488028	Sulem P	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488028	Two newly identified genetic determinants of pigmentation in Europeans.	Freckles	5,130 Icelandic individuals	3,330 European ancestry individuals	20q11.22	20;20	34150806;34141638	ASIP	AL031668.2 - ASIP; AL031668.2 - ASIP				NA	NA	rs1015362-G; rs4911414-T	rs1015362; rs4911414	0	NA	regulatory_region_variant; regulatory_region_variant	NA	0.08	8e-29	28.0969100130081		1.95	[1.65-2.32]	Illumina [316515]	N
2008-07-01	18488028	Sulem P	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488028	Two newly identified genetic determinants of pigmentation in Europeans.	Skin sensitivity to sun	5,130 Icelandic individuals	3,330 European ancestry individuals	20q11.22	20;20	34150806;34141638	ASIP	AL031668.2 - ASIP; AL031668.2 - ASIP				NA	NA	rs1015362-G; rs4911414-T	rs1015362; rs4911414	0	NA	regulatory_region_variant; regulatory_region_variant	NA	0.08	2e-24	23.698970004336		1.76	[1.49-2.08]	Illumina [316515]	N
2008-06-27	18488028	Sulem P	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488028	Two newly identified genetic determinants of pigmentation in Europeans.	Blond vs. brown hair color	5,130 European ancestry individuals	3,330 European ancestry individuals	11q13.3	11	69078931	TPCN2	TPCN2, AP003071.5			ENSG00000162341, ENSG00000287725	NA	NA	rs35264875-T	rs35264875	0	35264875	missense_variant	0	0.22	4e-30	29.397940008672		2.49	[1.96-3.15]	Illumina [316515]	N
2008-06-27	18488028	Sulem P	2008-05-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18488028	Two newly identified genetic determinants of pigmentation in Europeans.	Red vs. non-red hair color	5,130 European ancestry individuals	3,330 European ancestry individuals	20q11.22	20;20	34150806;34141638	ASIP	AL031668.2 - ASIP; AL031668.2 - ASIP				NA	NA	rs1015362-G; rs4911414-T	rs1015362; rs4911414	0	NA	regulatory_region_variant; regulatory_region_variant	NA	0.08	3e-09	8.52287874528034		1.76	[1.34-2.31]	Illumina [316515]	N
2010-09-01	20637204	Ochi H	2010-07-13	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/20637204	ITPA polymorphism affects ribavirin-induced anemia and outcomes of therapy--a genome-wide study of Japanese HCV virus patients.	Ribavirin-induced anemia	453 Japanese ancestry individuals	470 Japanese ancestry individuals	20p13	20	3213196	DDRGK1, ITPA	ITPA			ENSG00000125877	NA	NA	rs1127354-A	rs1127354	0	1127354	missense_variant	0	NR	4e-44	43.397940008672		NA		Illumina [510537]	N
2009-05-20	19426955	Himes BE	2009-05-07	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19426955	Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.	Asthma	359 European ancestry cases, 846 European ancestry controls	2,981 European ancestry cases, 12,358 European ancestry controls, 769 European ancestry and hispanic cases, 1,007 European ancestry and hispanic controls, 592 Hispanic cases with their 1,184 Hispanic parental controls, 2,258 African American cases, 3,006 African American controls	5q12.1	5	60073967	PDE4D	PDE4D			ENSG00000113448	NA	NA	rs1588265-C	rs1588265	0	1588265	intron_variant	0	0.29	3e-08	7.52287874528034		1.18	[1.08-1.30]	Illumina [518230]	N
2009-11-09	19836008	Landi MT	2009-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19836008	A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.	Lung adenocarcinoma	5,739 European ancestry cases, 5,848 European ancestry controls	7,561 European ancestry cases, 13,818 European ancestry controls	6p21.33	6	31652743	APOM, BAT3	APOM, APOM, APOM, APOM, APOM, APOM, APOM			ENSG00000227567, ENSG00000226215, ENSG00000204444, ENSG00000235754, ENSG00000231974, ENSG00000224290, ENSG00000206409	NA	NA	rs3117582-C	rs3117582	0	3117582	intron_variant	0	0.10	5e-12	11.301029995664		1.22	[1.15-1.29]	Illumina [515922]	N
2009-11-09	19836008	Landi MT	2009-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19836008	A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.	Lung adenocarcinoma	5,739 European ancestry cases, 5,848 European ancestry controls	7,561 European ancestry cases, 13,818 European ancestry controls	15q25.1	15	78601997	CHRNA5, CHRNA3	CHRNA3			ENSG00000080644	NA	NA	rs1051730-T	rs1051730	0	1051730	synonymous_variant	0	0.35	2e-51	50.698970004336		1.31	[1.27-1.36]	Illumina [515922]	N
2009-11-09	19836008	Landi MT	2009-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19836008	A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.	Lung adenocarcinoma	5,739 European ancestry cases, 5,848 European ancestry controls	7,561 European ancestry cases, 13,818 European ancestry controls	5p15.33	5	1342599	CLPTM1L	CLPTM1L			ENSG00000049656	NA	NA	rs31489-C	rs31489	0	31489	intron_variant	0	0.59	2e-10	9.69897000433602		1.12	[1.09-1.16]	Illumina [515922]	N
2009-11-09	19836008	Landi MT	2009-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19836008	A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.	Lung adenocarcinoma	5,739 European ancestry cases, 5,848 European ancestry controls	7,561 European ancestry cases, 13,818 European ancestry controls	6p22.1	6	28808340	TRNAA-UGC	NOP56P1 - AL662890.1	ENSG00000273323	ENSG00000225173		24336	29529	rs4324798-A	rs4324798	0	4324798	intergenic_variant	1	0.09	2e-08	7.69897000433602		1.16	[1.09-1.24]	Illumina [515922]	N
2009-11-09	19836008	Landi MT	2009-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19836008	A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.	Lung adenocarcinoma	5,739 European ancestry cases, 5,848 European ancestry controls	7,561 European ancestry cases, 13,818 European ancestry controls	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-G	rs2736100	0	2736100	3_prime_UTR_variant	0	0.50	2e-10	9.69897000433602		1.12	[1.08-1.16]	Illumina [515922]	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	1q42.2	1	232383404	SIPA1L2	RN7SL299P - SIPA1L2	ENSG00000242794	ENSG00000116991		160259	14561	rs669408-C	rs669408	0	669408	regulatory_region_variant	1	0.41	1e-06	6		1.33	[1.18-1.49]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	11p11.2	11	46357892	DGKZ, MDK, AMBRA1, HARBI1, ATG13, F2, CKAP5	DGKZ			ENSG00000149091	NA	NA	rs11038871-C	rs11038871	0	11038871	intron_variant	0	0.248	2e-06	5.69897000433602		1.36	[1.19-1.55]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	10q23.31	10	89012072	ACTA2, FAS	FAS			ENSG00000026103	NA	NA	rs2234978-A	rs2234978	0	2234978	synonymous_variant	0	0.31	6e-06	5.22184874961636		1.32	[1.16-1.50]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	6p21.32	6	32638107	HLA-DRB1	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs2187668-A	rs2187668	0	2187668	intron_variant	0	0.13	2e-33	32.698970004336		2.53	[2.17-2.95]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	2q24.2	2	162267541	IFIH1	IFIH1			ENSG00000115267	NA	NA	rs1990760-?	rs1990760	0	1990760	missense_variant	0	0.61	7e-10	9.15490195998574		1.49	[1.32-1.69]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	18p11.31	18	5857092	L3MBTL4	MIR3976HG			ENSG00000261738	NA	NA	rs11662763-?	rs11662763	0	11662763	intron_variant	0	0.85	5e-06	5.30102999566398		1.56	[1.30-1.89]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	7q21.3	7	96785743	SHFM1	SEM1 - MARK2P10	ENSG00000127922	ENSG00000227284		75852	72439	rs12669076-?	rs12669076	0	12669076	regulatory_region_variant	1	0.66	2e-06	5.69897000433602		1.35	[1.18-1.54]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	3q25.1	3	151862085	AADAC, SUCNR1	AADACL2-AS1			ENSG00000242908	NA	NA	rs6798928-?	rs6798928	0	6798928	intron_variant	0	0.58	3e-06	5.52287874528034		1.35	[1.19-1.54]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	8q24.21	8	128234169	PVT1	RN7SKP226 - AC100822.1	ENSG00000201782	ENSG00000286034		13366	88962	rs10492294-?	rs10492294	0	10492294	intergenic_variant	1	0.81	4e-06	5.39794000867204		1.49	[1.27-1.75]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	9p21.2	9	27882655	IFNK, LINGO2	AL360014.1 - AL353746.1	ENSG00000260390	ENSG00000260412		38174	54962	rs7029145-A	rs7029145	0	7029145	intergenic_variant	1	0.466	9e-06	5.04575749056067		1.29	[1.15-1.46]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	6p21.32	6	32619077	HLA-DRB1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		29229	9102	rs9271366-?	rs9271366	0	9271366	intergenic_variant	1	0.85	3e-33	32.5228787452803		7.69	[5.26-11.11]	Illumina [2057134] (imputed)	N
2010-09-21	20694011	Ferreira RC	2010-08-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20694011	Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency.	Immunoglobulin A	430 European ancestry cases, 1,090 European ancestry controls	342 European ancestry cases, 886 European ancestry controls	16p13.13	16	10987392	CLEC16A	CLEC16A			ENSG00000038532	NA	NA	rs6498142-?	rs6498142	0	6498142	intron_variant	0	0.83	2e-07	6.69897000433602		1.56	[1.30-1.85]	Illumina [2057134] (imputed)	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	18q12.1	18	34065415	NOL4	NOL4			ENSG00000101746	NA	NA	rs7239368-?	rs7239368	0	7239368	intron_variant	0	0.42	9e-06	5.04575749056067	(remission)	1.45	[1.22-1.69]	Affymetrix [430198]	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	7q36.3	7	157087704	UBE3C	AC006967.2 - AC006967.1	ENSG00000236102	ENSG00000229365		29190	251	rs6966038-?	rs6966038	0	6966038	intergenic_variant	1	0.19	5e-07	6.30102999566398	(response)	1.64	[1.35-1.99]	Affymetrix [430198]	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	20q13.31	20	57063694	BMP7	RNU6-929P - AL157414.2	ENSG00000207158	ENSG00000231078		277607	42047	rs6127921-?	rs6127921	0	6127921	intergenic_variant	1	0.82	3e-06	5.52287874528034	(response)	1.64	[1.33-2.04]	Affymetrix [430198]	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	15q22.2	15	61037589	RORA	RORA			ENSG00000069667	NA	NA	rs809736-?	rs809736	0	809736	intron_variant	0	0.17	8e-06	5.09691001300806	(response)	1.52	[1.27-1.83]	Affymetrix [430198]	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	20q13.31	20	57063694	BMP7	RNU6-929P - AL157414.2	ENSG00000207158	ENSG00000231078		277607	42047	rs6127921-?	rs6127921	0	6127921	intergenic_variant	1	0.81	1e-06	6	(remission)	1.75	[1.39-2.17]	Affymetrix [430198]	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	7q36.3	7	157087704	UBE3C	AC006967.2 - AC006967.1	ENSG00000236102	ENSG00000229365		29190	251	rs6966038-?	rs6966038	0	6966038	intergenic_variant	1	0.20	4e-07	6.39794000867204	(remission)	1.68	[1.37-2.04]	Affymetrix [430198]	N
2009-11-25	19846067	Garriock HA	2009-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19846067	A genomewide association study of citalopram response in major depressive disorder.	Response to citalopram treatment	Up to 659 European ancestry responders, up to 121 African American responders, up to 103 Hispanic responders, 408 European ancestry non-responders, 120 African American non-responders, 80 Hispanic non-responders	NA	21q21.3	21	27293028	EIF4A1P	GPX1P2 - AP001605.1	ENSG00000215326	ENSG00000231236		149079	65857	rs2830840-?	rs2830840	0	2830840	intergenic_variant	1	0.46	5e-06	5.30102999566398	(remission)	1.47	[1.23-1.72]	Affymetrix [430198]	N
2009-06-01	19448623	Ong KK	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448623	Genetic variation in LIN28B is associated with the timing of puberty.	Menarche (age at onset)	4,714 European ancestry female individuals	16,373 European ancestry female individuals	6q16.3	6	104960124	LIN28B	LIN28B			ENSG00000187772	NA	NA	rs314276-C	rs314276	0	314276	intron_variant	0	0.67	4e-16	15.397940008672		0.14	[0.11-0.17] year decrease	Affymetrix [up to 390631]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	HDL cholesterol	4,763 Northern Finnish founder individuals	NA	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	1	0.28	7e-29	28.1549019599857		0.09	[0.08-0.11] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	HDL cholesterol	4,763 Northern Finnish founder individuals	NA	11p11.2	11	47264739	NR1H3	NR1H3			ENSG00000025434	NA	NA	rs7120118-G	rs7120118	0	7120118	intron_variant	0	0.42	4e-08	7.39794000867204		0.04	[0.03-0.05] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	HDL cholesterol	4,763 Northern Finnish founder individuals	NA	16q22.1	16	67979568	LCAT	DPEP3			ENSG00000141096	NA	NA	rs255049-G	rs255049	0	255049	intron_variant	0	0.22	3e-08	7.52287874528034		0.05	[0.03-0.07] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	HDL cholesterol	4,763 Northern Finnish founder individuals	NA	17p13.3	17	2525214	intergenic	METTL16 - RN7SL33P	ENSG00000127804	ENSG00000243049		13323	32539	rs9891572-A	rs9891572	0	9891572	intergenic_variant	1	0.16	2e-07	6.69897000433602		0.05	[0.048-0.051] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	HDL cholesterol	4,763 Northern Finnish founder individuals	NA	15q21.3	15	58391167	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs1532085-A	rs1532085	0	1532085	intron_variant	0	0.44	2e-10	9.69897000433602		0.05	[0.03-0.06] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	1p13.3	1	109275908	CELSR2, PSRC1, SORT1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		157	3648	rs646776-G	rs646776	0	646776	intergenic_variant	1	0.21	2e-12	11.698970004336		0.16	[0.11-0.20] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	2p24.1	2	21009323	APOB	APOB			ENSG00000084674	NA	NA	rs693-A	rs693	0	693	synonymous_variant	0	0.41	3e-11	10.5228787452803		0.12	[0.09-0.16] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	11q12.2	11	61802358	FADS1, FADS2	FADS1, FADS2			ENSG00000149485, ENSG00000134824	NA	NA	rs174546-A	rs174546	0	174546	3_prime_UTR_variant	0	0.44	1e-07	7		0.1	[0.06-0.13] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	19p13.2	19	11084354	LDLR	SMARCA4 - LDLR	ENSG00000127616	ENSG00000130164		4928	5008	rs11668477-G	rs11668477	0	11668477	regulatory_region_variant	1	0.18	2e-07	6.69897000433602		0.13	[0.08-0.17] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	19q13.32	19	44892009	APO cluster	TOMM40			ENSG00000130204	NA	NA	rs157580-G	rs157580	0	157580	intron_variant	0	0.29	5e-08	7.30102999566398		0.11	[0.07-0.15] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	1q32.2	1	207701830	CR1L	CR1L			ENSG00000197721	NA	NA	rs4844614-A	rs4844614	0	4844614	intron_variant	0	0.32	2e-07	6.69897000433602		0.1	[0.06-0.14] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	LDL cholesterol	4,763 Northern Finnish founder individuals	NA	Xq12	X	67722783	AR	AR			ENSG00000169083	NA	NA	rs5031002-A	rs5031002	0	5031002	intron_variant	0	0.02	2e-07	6.69897000433602		0.3	[0.18-0.41] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	2p24.1	2	21014672	APOB	APOB			ENSG00000084674	NA	NA	rs673548-A	rs673548	0	673548	intron_variant	0	0.27	2e-08	7.69897000433602	(TG)	0.08	[0.05-0.11] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-A	rs1260326	0	1260326	missense_variant	0	0.35	4e-10	9.39794000867204	(TG)	0.09	[0.06-0.12] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	15q14	15	38856448	intergenic	LINC02694			ENSG00000175779	NA	NA	rs2624265-G	rs2624265	0	2624265	intron_variant	0	0.42	4e-07	6.39794000867204	(TG)	0.07	[0.04-0.10] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	1p31.3	1	65703996	LEPR	AL513493.1			ENSG00000285079	NA	NA	rs12753193-G	rs12753193	0	12753193	non_coding_transcript_exon_variant	0	0.45	4e-07	6.39794000867204	(CRP)	0.13	[-0.02-0.27] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	2q31.1	2	168906638	G6PC2, ABCB11	SPC25, SPC25, G6PC2, G6PC2			ENSG00000152253, ENSG00000277909, ENSG00000152254, ENSG00000278373	NA	NA	rs560887-A	rs560887	0	560887	intron_variant	0	0.31	6e-10	9.22184874961636	(GLU)	0.06	[0.04-0.07] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	1q23.2	1	159709026	CRP	CRPP1 - CRP	ENSG00000223603	ENSG00000132693		3419	3263	rs2794520-A	rs2794520	0	2794520	intergenic_variant	1	0.36	3e-22	21.5228787452803	(CRP)	0.47	[0.32-0.62] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	7p21.2	7	15024208	intergenic	GTF3AP5 - AC006458.1	ENSG00000225816	ENSG00000227489		38134	41999	rs10244051-C	rs10244051	0	10244051	intergenic_variant	1	0.46	1e-07	7	(GLU)	0.05	[0.03-0.06] mmol/l increase	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	10q23.31	10	89612776	PANK1	PANK1			ENSG00000152782	NA	NA	rs11185790-A	rs11185790	0	11185790	intron_variant	0	0.21	3e-07	6.52287874528034	(INS)	0.31	[0.18-0.44] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	8p21.3	8	19973410	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		6151	105704	rs10096633-A	rs10096633	0	10096633	regulatory_region_variant	1	0.098	5e-08	7.30102999566398	(TG)	0.12	[0.07-0.17] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	12q24.31	12	120951159	LEF1	HNF1A-AS1			ENSG00000241388	NA	NA	rs2650000-A	rs2650000	0	2650000	intron_variant	0	0.45	3e-11	10.5228787452803	(CRP)	0.4	[0.25-0.55] mmol/l decrease	Illumina [329091]	N
2009-01-14	19060910	Sabatti C	2008-12-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19060910	Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.	Metabolic traits	4,763 Northern Finnish founder individuals	NA	11q14.3	11	92989595	MTNR1B	MTNR1B - RPL26P31	ENSG00000134640	ENSG00000242807		4529	62800	rs1447352-G	rs1447352	0	1447352	intergenic_variant	1	0.42	6e-08	7.22184874961636	(GLU)	0.05	[0.03-0.06] mmol/l decrease	Illumina [329091]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	15q25.2	15	82683530	AP3B2	CPEB1-AS1, AP3B2			ENSG00000259462, ENSG00000103723	NA	NA	rs11638815-C	rs11638815	0	11638815	intron_variant	0	0.25	1e-06	6	(Change)	4.1	[2.14-6.06] nmol/min/ml increase	Illumina [796174]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	6q25.3	6	160589086	LPA	LPA			ENSG00000198670	NA	NA	rs10455872-G	rs10455872	0	10455872	intron_variant	0	0.05	2e-16	15.698970004336	(percent change)	4.8	[0.82-2.78] percent increase	Illumina [796174]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	4q22.1	4	88124179	ABCG2	ABCG2			ENSG00000118777	NA	NA	rs2199936-A	rs2199936	0	2199936	intron_variant	0	0.11	2e-10	9.69897000433602	(percent change)	2.8	[1.82-3.78] percent decrease	Illumina [796174]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	1p22.3	1	84802560	EDG7	AC104169.1 - LPAR3	ENSG00000285325	ENSG00000171517		15846	9042	rs10782529-C	rs10782529	0	10782529	intergenic_variant	1	0.36	4e-06	5.39794000867204	(percent change)	1.7	[1.11-2.29] percent increase	Illumina [796174]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	14q32.2	14	98033121	C14orf177	LINC01550 - AL163932.1	ENSG00000246223	ENSG00000259097		54997	35040	rs10144042-A	rs10144042	0	10144042	intergenic_variant	1	0.24	2e-06	5.69897000433602	(percent change)	1.4	[0.62-2.18] percent decrease	Illumina [796174]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	15q23	15	69105686	NOX5	AC027088.2 - GLCE	ENSG00000259222	ENSG00000138604		5699	54898	rs1392635-A	rs1392635	0	1392635	intergenic_variant	1	0.26	2e-06	5.69897000433602	(percent change)	1.7	[0.92-2.48] percent increase	Illumina [796174]	N
2013-01-31	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity change in response to statin therapy	2,673 European ancestry cases, 2,656 European ancestry controls	NA	17q25.3	17	80350459	RNF213	RNF213			ENSG00000173821	NA	NA	rs12051723-T	rs12051723	0	12051723	intron_variant	0	0.14	3e-06	5.52287874528034	(percent change)	2.2	[1.22-3.18] percent increase	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	17q23.1	17	59772890	TMEM49	VMP1			ENSG00000062716	NA	NA	rs11650106-C	rs11650106	0	11650106	intron_variant	0	0.48	3e-09	8.52287874528034	(activity)	0.0092	[0.0039-0.0145] ng/ml decrease	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	12q24.31	12	124832197	SCARB1	SCARB1			ENSG00000073060	NA	NA	rs11057841-T	rs11057841	0	11057841	intron_variant	0	0.15	6e-14	13.2218487496164	(activity)	0.0286	[0.019-0.038] ng/ml increase	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-T	rs1260326	0	1260326	missense_variant	0	0.44	5e-06	5.30102999566398	(mass)	0.0053	[-0.00215-0.01275] ng/ml decrease	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-T	rs3764261	0	3764261	regulatory_region_variant	1	0.34	7e-21	20.1549019599857	(mass)	0.0224	[0.014-0.030] ng/ml increase	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	6p12.3	6	46714342	PLA2G7	PLA2G7			ENSG00000146070	NA	NA	rs1362931-A	rs1362931	0	1362931	intron_variant	0	0.19	3e-19	18.5228787452803	(activity)	0.0231	[0.016-0.030] ng/ml increase	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	11q12.2	11	60230193	MS4A4E	MS4A4E, MS4A4A			ENSG00000214787, ENSG00000110079	NA	NA	rs600550-T	rs600550	0	600550	intron_variant	0	0.38	2e-11	10.698970004336	(activity)	0.0137	[0.0068-0.0206] ng/ml decrease	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	19q13.32	19	44912383	APOE, APOC1	AC011481.3			ENSG00000280087	NA	NA	rs445925-T	rs445925	0	445925	non_coding_transcript_exon_variant	0	0.11	1e-56	56	(activity)	0.071	[0.049-0.093] ng/ml decrease	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	2p24.1	2	21008720	APOB	APOB			ENSG00000084674	NA	NA	rs6413458-T	rs6413458	0	6413458	synonymous_variant	0	0.02	2e-07	6.69897000433602	(mass)	0.0398	[0.0088-0.0708] ng/ml decrease	Illumina [796174]	N
2013-01-30	23118302	Chu AY	2012-11-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/23118302	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	Lipoprotein-associated phospholipase A2 activity and mass	6,851 European ancestry individuals	13,664 European ancestry individuals	1p13.3	1	109274968	SORT1	CELSR2			ENSG00000143126	NA	NA	rs12740374-T	rs12740374	0	12740374	3_prime_UTR_variant	0	0.22	2e-22	21.698970004336	(activity)	0.0344	[0.027-0.042] ng/ml decrease	Illumina [796174]	N
2008-09-15	17975299	Webster JA	2007-11-01	Neurodegener Dis	www.ncbi.nlm.nih.gov/pubmed/17975299	Sorl1 as an Alzheimer's disease predisposition gene?	Alzheimer's disease	664 cases, 422 controls	NA	19q13.32	19	44919689	APOE	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-?	rs4420638	0	4420638	regulatory_region_variant	1	NR	1e-39	39		NA		Affymetrix [~ 502627]	N
2008-06-16	17435756	Rioux JD	2007-04-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17435756	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	Crohn's disease	946 cases, 977 controls	530 trios, 353 cases, 207 controls	16q12.1	16	50722970	CARD15	NOD2			ENSG00000167207	NA	NA	rs2076756-?	rs2076756	0	2076756	intron_variant	0	0.24	7e-14	13.1549019599857		NA		Illumina [304413]	N
2008-06-16	17435756	Rioux JD	2007-04-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17435756	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	Crohn's disease	946 cases, 977 controls	530 trios, 353 cases, 207 controls	10q21.2	10	62710915	intergenic	AC067751.1			ENSG00000238280	NA	NA	rs224136-?	rs224136	0	224136	intron_variant	0	0.81	1e-10	10		1.67	[NR]	Illumina [304413]	N
2008-06-16	17435756	Rioux JD	2007-04-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17435756	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	Crohn's disease	946 cases, 977 controls	530 trios, 353 cases, 207 controls	1p31.3	1	67215986	IL23R	IL23R, C1orf141			ENSG00000162594, ENSG00000203963	NA	NA	rs7517847-?	rs7517847	0	7517847	intron_variant	0	0.40	3e-12	11.5228787452803		NA		Illumina [304413]	N
2008-06-16	17435756	Rioux JD	2007-04-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17435756	Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis.	Crohn's disease	946 cases, 977 controls	530 trios, 353 cases, 207 controls	2q37.1	2	233274722	ATG16L1	ATG16L1, ATG16L1			ENSG00000085978, ENSG00000281089	NA	NA	rs2241880-G	rs2241880	0	2241880	missense_variant	0	0.55	1e-13	13		1.45	[1.27-1.64]	Illumina [304413]	N
2008-06-16	18326623	Gold B	2008-03-11	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/18326623	Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.	Breast cancer	249 Ashkenazi Jewish non-BRCA1/2 carriers cases, 299 Ashkenazi Jewish non-BRCA1/2 carriers controls	1,193 Ashkenazi Jewish non-BRCA1/2 carriers  cases,1,166 Ashkenazi Jewish non-BRCA1/2 carriers controls	6q22.33	6	127279485	ECHDC1, RNF146	RNF146			ENSG00000118518	NA	NA	rs2180341-G	rs2180341	0	2180341	intron_variant	0	0.21	3e-08	7.52287874528034		1.41	[1.25-1.59]	Affymetrix [150080]	N
2009-04-14	19349984	Esparza-Gordillo J	2009-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19349984	A common variant on chromosome 11q13 is associated with atopic dermatitis.	Atopic dermatitis	939 European ancestry cases, 975 European ancestry controls, 1,097 European ancestry individuals from 270 families	2,637 European ancestry cases, 3,957 European ancestry controls	11q13.5	11	76590272	C11orf30	EMSY - AP001189.2	ENSG00000158636	ENSG00000254755		37247	751	rs7927894-A	rs7927894	0	7927894	intergenic_variant	1	0.36	8e-10	9.09691001300806		1.22	[1.15-1.30]	Affymetrix [342303]	N
2008-06-16	17401363	Yeager M	2007-04-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17401363	Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.	Prostate cancer	1,172 European ancestry cases, 1,157 European ancestry controls	3,124 European ancestry cases, 3,142 European ancestry controls	8q24.21	8	127472793	intergenic	CASC8			ENSG00000246228	NA	NA	rs1447295-A	rs1447295	0	1447295	intron_variant	0	0.11	2e-14	13.698970004336		1.43	[1.29-1.59]	Illumina [538548]	N
2008-06-16	17401363	Yeager M	2007-04-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17401363	Genome-wide association study of prostate cancer identifies a second risk locus at 8q24.	Prostate cancer	1,172 European ancestry cases, 1,157 European ancestry controls	3,124 European ancestry cases, 3,142 European ancestry controls	8q24.21	8	127401060	intergenic	PCAT1, CCAT2, POU5F1B, CASC8			ENSG00000253438, ENSG00000280997, ENSG00000212993, ENSG00000246228	NA	NA	rs6983267-G	rs6983267	0	6983267	non_coding_transcript_exon_variant	0	0.50	9e-13	12.0457574905607		1.26	[1.13-1.41]	Illumina [538548]	N
2008-06-16	17999355	Stokowski RP	2007-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/17999355	A genomewide association study of skin pigmentation in a South Asian population.	Skin pigmentation	363 South Asian ancestry low maxL* individuals, 374 South Asian ancestry high maxL* individuals	116 South Asian ancestry low maxL* individuals, 115 South Asian ancestry high maxL* individuals	11q14.3	11	89178528	TYR	TYR			ENSG00000077498	NA	NA	rs1042602-C	rs1042602	0	1042602	missense_variant	0	0.84	4e-10	9.39794000867204		4.36	[2.64-7.20]	Perlegen [1502205]	N
2008-06-16	17999355	Stokowski RP	2007-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/17999355	A genomewide association study of skin pigmentation in a South Asian population.	Skin pigmentation	363 South Asian ancestry low maxL* individuals, 374 South Asian ancestry high maxL* individuals	116 South Asian ancestry low maxL* individuals, 115 South Asian ancestry high maxL* individuals	5p13.2	5	33951588	SLC45A2	SLC45A2, SLC45A2			ENSG00000164175, ENSG00000281919	NA	NA	rs16891982-C	rs16891982	0	16891982	missense_variant	0	0.83	3e-11	10.5228787452803		4.86	[2.88-8.21]	Perlegen [1502205]	N
2008-06-16	17999355	Stokowski RP	2007-10-15	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/17999355	A genomewide association study of skin pigmentation in a South Asian population.	Skin pigmentation	363 South Asian ancestry low maxL* individuals, 374 South Asian ancestry high maxL* individuals	116 South Asian ancestry low maxL* individuals, 115 South Asian ancestry high maxL* individuals	15q21.1	15	48099968	SLC24A5	AC092078.2 - SLC24A5	ENSG00000259754	ENSG00000188467		49461	21022	rs1834640-G	rs1834640	0	1834640	intergenic_variant	1	0.08	1e-50	50		12.5	[8.33-20.0]	Perlegen [1502205]	N
2009-01-14	19114657	Wang Y	2008-12-29	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/19114657	From the Cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene.	Blood pressure	542 Old Order Amish individuals	5,229 European ancestry individuals, 1,347 Amish individuals, 575 Hutterite individuals	2q24.3	2	168184876	STK39	STK39			ENSG00000198648	NA	NA	rs6749447-G	rs6749447	0	6749447	intron_variant	0	0.28	2e-07	6.69897000433602		1.9	[1.2-2.6] mm Hg increase in DBP	Affymetrix [79447]	N
2008-06-22	18454148	Loos RJ	2008-05-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18454148	Common variants near MC4R are associated with fat mass, weight and risk of obesity.	Body mass index	16,876 European ancestry adult individuals	60,352 European ancestry adult individuals, 5,988 European ancestry children	16q12.2	16	53775335	FTO	FTO			ENSG00000140718	NA	NA	rs1121980-?	rs1121980	0	1121980	intron_variant	0	NR	4e-08	7.39794000867204		0.06	[0.04-0.08] unit increase	Affymetrix [344883]	N
2008-06-22	18454148	Loos RJ	2008-05-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18454148	Common variants near MC4R are associated with fat mass, weight and risk of obesity.	Body mass index	16,876 European ancestry adult individuals	60,352 European ancestry adult individuals, 5,988 European ancestry children	18q21.32	18	60183864	MC4R	RNU4-17P - AC090771.1	ENSG00000202468	ENSG00000267620		20157	12691	rs17782313-C	rs17782313	0	17782313	intergenic_variant	1	0.24	3e-15	14.5228787452803		0.05	[0.04-0.06] unit increase	Affymetrix [344883]	N
2008-06-16	17522711	Lencz T	2007-03-20	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/17522711	Converging evidence for a pseudoautosomal cytokine receptor gene locus in schizophrenia.	Schizophrenia	178 European ancestry cases, 144 European ancestry controls	NA	Xp22.33	X	1029445	CSF2RA, IL3RA	RPL14P5 - CRLF2	ENSG00000225661	ENSG00000205755		19344	158104	rs4129148-C	rs4129148	0	4129148	intergenic_variant	1	NR	4e-07	6.39794000867204		3.23	[2.04-5.15]	Affymetrix [439511]	N
2008-09-08	17474819	Coon KD	2007-04-01	J Clin Psychiatry	www.ncbi.nlm.nih.gov/pubmed/17474819	A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease.	Alzheimer's disease (late onset)	664 European ancestry cases, 422 European ancestry controls	NA	19q13.32	19	44919689	APOE	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-?	rs4420638	0	4420638	regulatory_region_variant	1	NR	1e-39	39		4.01	[NR]	Affymetrix [~ 502627]	N
2008-06-23	17395743	Hanson RL	2007-04-01	Diabetes	www.ncbi.nlm.nih.gov/pubmed/17395743	Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based genome-wide single nucleotide polymorphism association study.	End-stage renal disease	105 Pima Indian ancestry cases, 102 Pima Indian ancestry controls	NA	8q24.21	8	128059915	PVT1	PVT1			ENSG00000249859	NA	NA	rs2648875-A	rs2648875	0	2648875	intron_variant	0	0.53	2e-06	5.69897000433602		2.97	[1.90-4.65]	Affymetrix [115352]	N
2008-06-22	18454146	Chambers JC	2008-05-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18454146	Common genetic variation near MC4R is associated with waist circumference and insulin resistance.	Waist circumference and related phenotypes	2,684 Indian Asian ancestry male individuals	7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals	8p21.3	8	20007664	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		40405	71450	rs2083637-?	rs2083637	0	2083637	intergenic_variant	1	NR	5e-06	5.30102999566398	(HDL cholesterol)	NA		Illumina [308067]	N
2008-06-22	18454146	Chambers JC	2008-05-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18454146	Common genetic variation near MC4R is associated with waist circumference and insulin resistance.	Waist circumference and related phenotypes	2,684 Indian Asian ancestry male individuals	7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-?	rs3764261	0	3764261	regulatory_region_variant	1	NR	1e-27	27	(HDL cholesterol)	NA		Illumina [308067]	N
2008-06-22	18454146	Chambers JC	2008-05-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18454146	Common genetic variation near MC4R is associated with waist circumference and insulin resistance.	Waist circumference and related phenotypes	2,684 Indian Asian ancestry male individuals	7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-?	rs1260326	0	1260326	missense_variant	0	NR	4e-08	7.39794000867204	(triglycerides)	NA		Illumina [308067]	N
2008-06-22	18454146	Chambers JC	2008-05-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18454146	Common genetic variation near MC4R is associated with waist circumference and insulin resistance.	Waist circumference and related phenotypes	2,684 Indian Asian ancestry male individuals	7,394 Indian Asian ancestry individuals, 4,561 European ancestry individuals	18q21.32	18	60217517	MC4R	AC090771.1 - AC090621.1	ENSG00000267620	ENSG00000267401		19345	76619	rs12970134-A	rs12970134	0	12970134	intergenic_variant	1	0.36	2e-09	8.69897000433602	(waist circumference)	0.88	[0.59-1.17] cm increase	Illumina [308067]	N
2009-09-30	20061627	Heinzen EL	2009-09-11	J Alzheimers Dis	www.ncbi.nlm.nih.gov/pubmed/20061627	Genome-wide scan of copy number variation in late-onset Alzheimer's disease.	Alzheimer's disease	331 European ancestry cases, 368 European ancestry controls	NA	10q24.31	10	100741814	PAX2	PAX2			ENSG00000075891	NA	NA	rs4509693-?	rs4509693	0	4509693	intron_variant	0	0.18	6e-06	5.22184874961636		NA		Illumina [~ 550000]	N
2009-09-30	20061627	Heinzen EL	2009-09-11	J Alzheimers Dis	www.ncbi.nlm.nih.gov/pubmed/20061627	Genome-wide scan of copy number variation in late-onset Alzheimer's disease.	Alzheimer's disease	331 European ancestry cases, 368 European ancestry controls	NA	1p31.1	1	83789052	TTLL7	LINC01725			ENSG00000233008	NA	NA	rs7539409-?	rs7539409	0	7539409	intron_variant	0	0.18	1e-06	6		NA		Illumina [~ 550000]	N
2009-09-30	20061627	Heinzen EL	2009-09-11	J Alzheimers Dis	www.ncbi.nlm.nih.gov/pubmed/20061627	Genome-wide scan of copy number variation in late-onset Alzheimer's disease.	Alzheimer's disease	331 European ancestry cases, 368 European ancestry controls	NA	6q24.3	6	148102235	SASH1	AL445123.1 - AL359382.1	ENSG00000234675	ENSG00000230205		81261	31574	rs9390537-?	rs9390537	0	9390537	regulatory_region_variant	1	0.22	8e-06	5.09691001300806		NA		Illumina [~ 550000]	N
2009-09-30	20061627	Heinzen EL	2009-09-11	J Alzheimers Dis	www.ncbi.nlm.nih.gov/pubmed/20061627	Genome-wide scan of copy number variation in late-onset Alzheimer's disease.	Alzheimer's disease	331 European ancestry cases, 368 European ancestry controls	NA	13q13.2	13	34080781	RFC3	AL160394.2 - VDAC1P12	ENSG00000280431	ENSG00000227254		647	1648	rs690705-?	rs690705	0	690705	intergenic_variant	1	0.25	6e-07	6.22184874961636		NA		Illumina [~ 550000]	N
2009-09-30	20061627	Heinzen EL	2009-09-11	J Alzheimers Dis	www.ncbi.nlm.nih.gov/pubmed/20061627	Genome-wide scan of copy number variation in late-onset Alzheimer's disease.	Alzheimer's disease	331 European ancestry cases, 368 European ancestry controls	NA	19q13.32	19	44892362	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	0	0.15	3e-11	10.5228787452803		NA		Illumina [~ 550000]	N
2012-03-03	22306654	Feenstra B	2012-02-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22306654	Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.	Infantile hypertrophic pyloric stenosis	1,001 European ancestry cases, 2,401 European ancestry controls	796 European ancestry cases, 876 European ancestry controls	3q25.1	3	152112520	MBNL1	AADACL2-AS1 - AC108718.1	ENSG00000242908	ENSG00000239941		184345	5653	rs11712066-A	rs11712066	0	11712066	intergenic_variant	1	0.75	2e-17	16.698970004336		1.61	[1.44-1.79]	Illumina [523420]	N
2012-03-03	22306654	Feenstra B	2012-02-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22306654	Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.	Infantile hypertrophic pyloric stenosis	1,001 European ancestry cases, 2,401 European ancestry controls	796 European ancestry cases, 876 European ancestry controls	3q25.2	3	153754374	intergenic	LINC02006			ENSG00000238755	NA	NA	rs573872-G	rs573872	0	573872	intron_variant	0	0.23	4e-12	11.397940008672		1.41	[1.28-1.56]	Illumina [523420]	N
2012-03-03	22306654	Feenstra B	2012-02-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22306654	Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.	Infantile hypertrophic pyloric stenosis	1,001 European ancestry cases, 2,401 European ancestry controls	796 European ancestry cases, 876 European ancestry controls	5q35.1	5	173168305	BNIP1, NKX2-5	BNIP1 - RPL7AP33	ENSG00000113734	ENSG00000254200		3918	57531	rs29784-A	rs29784	0	29784	intergenic_variant	1	0.45	1e-15	15		1.42	[1.30-1.55]	Illumina [523420]	N
2012-03-03	22306654	Feenstra B	2012-02-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22306654	Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.	Infantile hypertrophic pyloric stenosis	1,001 European ancestry cases, 2,401 European ancestry controls	796 European ancestry cases, 876 European ancestry controls	6q23.2	6	133837662	NR	LINC01312, TARID			ENSG00000223586, ENSG00000227954	NA	NA	rs1208285-C	rs1208285	0	1208285	non_coding_transcript_exon_variant	0	0.39	6e-07	6.22184874961636		1.25	[1.14-1.36]	Illumina [523420]	N
2012-03-03	22306654	Feenstra B	2012-02-05	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22306654	Common variants near MBNL1 and NKX2-5 are associated with infantile hypertrophic pyloric stenosis.	Infantile hypertrophic pyloric stenosis	1,001 European ancestry cases, 2,401 European ancestry controls	796 European ancestry cases, 876 European ancestry controls	11q23.3	11	116912258	NR	SIK3			ENSG00000160584	NA	NA	rs11216185-G	rs11216185	0	11216185	intron_variant	0	0.05	1e-07	7		1.57	[1.33-1.86]	Illumina [523420]	N
2009-06-04	19448621	He C	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448621	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	Menarche and menopause (age at onset)	17,438 European ancestry female individuals	NA	20p12.3	20	5967581	MCM8, TRMT6	AL035461.3, MCM8			ENSG00000286235, ENSG00000125885	NA	NA	rs16991615-A	rs16991615	0	16991615	missense_variant	0	0.06	1e-21	21	(age at natural menopause)	1.07	[0.85-1.29] years increase	Illumina [317759]	N
2009-06-04	19448621	He C	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448621	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	Menarche and menopause (age at onset)	17,438 European ancestry female individuals	NA	6p24.2	6	10897255	GCM2, SYCP2L	AL024498.2, SYCP2L			ENSG00000272162, ENSG00000153157	NA	NA	rs2153157-T	rs2153157	0	2153157	intron_variant	0	0.49	5e-08	7.30102999566398	(age at natural menopause)	0.29	[0.19-0.39] years increase	Illumina [317759]	N
2009-06-04	19448621	He C	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448621	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	Menarche and menopause (age at onset)	17,438 European ancestry female individuals	NA	6q16.3	6	104959787	LIN28B	LIN28B			ENSG00000187772	NA	NA	rs314277-A	rs314277	0	314277	intron_variant	0	0.14	3e-13	12.5228787452803	(age at menarche)	0.16	[0.12-0.20] years increase	Illumina [317759]	N
2009-06-04	19448621	He C	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448621	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	Menarche and menopause (age at onset)	17,438 European ancestry female individuals	NA	9q31.2	9	106174393	intergenic	LINC01505			ENSG00000234323	NA	NA	rs7861820-C	rs7861820	0	7861820	intron_variant	0	0.48	3e-09	8.52287874528034	(age at menarche)	0.09	[0.06-0.12] years decrease	Illumina [317759]	N
2009-06-04	19448621	He C	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448621	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	Menarche and menopause (age at onset)	17,438 European ancestry female individuals	NA	19q13.42	19	55308477	BRSK1	BRSK1			ENSG00000160469	NA	NA	rs1172822-T	rs1172822	0	1172822	intron_variant	0	0.37	2e-19	18.698970004336	(age at natural menopause)	0.49	[0.38-0.60] years decrease	Illumina [317759]	N
2009-06-04	19448621	He C	2009-05-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448621	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.	Menarche and menopause (age at onset)	17,438 European ancestry female individuals	NA	5q35.2	5	176951573	UIMC1	UIMC1			ENSG00000087206	NA	NA	rs365132-T	rs365132	0	365132	synonymous_variant	0	0.49	8e-14	13.0969100130081	(age at natural menopause)	0.39	[0.29-0.49] years increase	Illumina [317759]	N
2009-09-09	19706858	Shuldiner AR	2009-08-26	JAMA	www.ncbi.nlm.nih.gov/pubmed/19706858	Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.	Response to clopidogrel therapy	429 Amish individuals	140 European ancestry individuals, 83 African American individuals, 4 individuals	10q23.33	10	94645745	CYP2C18, CYP2C9, CYP2C8, CYP2C19	HELLS - CTBP2P2	ENSG00000119969	ENSG00000235746		31840	619	rs12777823-?	rs12777823	0	12777823	intergenic_variant	1	0.17	2e-13	12.698970004336	(Amish)	NA		Affymetrix [400230]	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	1p36.12	1	22384980	ZBTB40	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		18498	43858	rs6426749-C	rs6426749	0	6426749	intergenic_variant	1	0.17	9e-08	7.04575749056067		0.08	[0.05-0.11] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	4q22.1	4	87854091	MEPE	MEPE - HSP90AB3P	ENSG00000152595	ENSG00000183199		7274	37752	rs1471403-T	rs1471403	0	1471403	intergenic_variant	1	0.34	8e-07	6.09691001300806		0.06	[0.04-0.08] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	11p15.2	11	15672916	SOX6	AC087379.2			ENSG00000254695	NA	NA	rs7117858-G	rs7117858	0	7117858	intron_variant	0	0.20	6e-10	9.22184874961636		0.09	[0.06-0.12] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	3p22.1	3	41096181	CTNNB1	AC099541.1 - AC009743.1	ENSG00000233096	ENSG00000233919		124603	66106	rs87938-A	rs87938	0	87938	regulatory_region_variant	1	0.45	8e-10	9.09691001300806		0.07	[0.05-0.09] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	5q14.3	5	89080244	MEF2C	MEF2C-AS1			ENSG00000248309	NA	NA	rs1366594-C	rs1366594	0	1366594	intron_variant	0	0.45	1e-13	13		0.09	[0.07-0.11] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	7q21.3	7	96504219	FLJ42280	SEM1			ENSG00000127922	NA	NA	rs7781370-T	rs7781370	0	7781370	intron_variant	0	0.34	5e-12	11.301029995664		0.08	[0.06-0.10] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	16q24.1	16	86677054	FOXL1	AC009154.1 - AC009154.2	ENSG00000261161	ENSG00000274478		8131	21064	rs10048146-G	rs10048146	0	10048146	regulatory_region_variant	1	0.19	2e-07	6.69897000433602		0.09	[0.06-0.12] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	11p11.2	11	46700671	ARHGAP1	ARHGAP1 - ZNF408	ENSG00000175220	ENSG00000175213		52	359	rs7932354-T	rs7932354	0	7932354	TF_binding_site_variant	1	0.29	4e-09	8.39794000867204		0.07	[0.05-0.09] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	17q21.31	17	45727828	CRHR1	LINC02210-CRHR1, LINC02210-CRHR1			ENSG00000263715, ENSG00000282456	NA	NA	rs9303521-T	rs9303521	0	9303521	intron_variant	0	0.46	4e-06	5.39794000867204		0.06	[0.04-0.07] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	17q21.31	17	44115817	HDAC5	HDAC5			ENSG00000108840	NA	NA	rs228769-G	rs228769	0	228769	intron_variant	0	0.20	2e-08	7.69897000433602		0.08	[0.05-0.11] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	6q25.1	6	151688503	ESR1	ESR1			ENSG00000091831	NA	NA	rs2941740-G	rs2941740	0	2941740	intron_variant	0	0.43	2e-10	9.69897000433602		0.07	[0.05-0.09] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	8q24.12	8	119000461	TNFRSF11B	COLEC10			ENSG00000184374	NA	NA	rs11995824-G	rs11995824	0	11995824	intron_variant	0	0.55	7e-09	8.15490195998574		0.07	[0.05-0.09] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (hip)	19,195 European ancestry individuals	NA	1p31.3	1	68169707	GPR177	WLS, GNG12-AS1			ENSG00000116729, ENSG00000232284	NA	NA	rs2566755-C	rs2566755	0	2566755	intron_variant	0	0.21	2e-12	11.698970004336		0.1	[0.07-0.13] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	12q13.13	12	53334171	SP7	SP7			ENSG00000170374	NA	NA	rs2016266-G	rs2016266	0	2016266	intron_variant	0	0.32	1e-08	8		0.07	[0.05-0.09] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	13q14.11	13	42377313	AKAP11	LINC02341			ENSG00000283554	NA	NA	rs9533090-T	rs9533090	0	9533090	intron_variant	0	0.50	5e-25	24.301029995664		0.12	[0.10-0.14] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	1p36.12	1	22371954	ZBTB40	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		5472	56884	rs7524102-G	rs7524102	0	7524102	intergenic_variant	1	0.17	3e-10	9.52287874528034		0.09	[0.06-0.12] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	16q24.1	16	86677054	FOXL1	AC009154.1 - AC009154.2	ENSG00000261161	ENSG00000274478		8131	21064	rs10048146-G	rs10048146	0	10048146	regulatory_region_variant	1	0.19	2e-08	7.69897000433602		0.09	[0.06-0.12] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	7p14.1	7	38096675	STARD3NL	SFRP4 - STARD3NL	ENSG00000106483	ENSG00000010270		70980	81547	rs1524058-T	rs1524058	0	1524058	intergenic_variant	1	0.40	1e-09	9		0.07	[0.05-0.09] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	1p31.3	1	68169392	GPR177	WLS, GNG12-AS1			ENSG00000116729, ENSG00000232284	NA	NA	rs1430742-C	rs1430742	0	1430742	intron_variant	0	0.21	3e-13	12.5228787452803		0.11	[0.07-0.14] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	17q21.31	17	45727828	CRHR1	LINC02210-CRHR1, LINC02210-CRHR1			ENSG00000263715, ENSG00000282456	NA	NA	rs9303521-T	rs9303521	0	9303521	intron_variant	0	0.46	1e-08	8		0.07	[0.05-0.09] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	17q21.31	17	44115817	HDAC5	HDAC5			ENSG00000108840	NA	NA	rs228769-G	rs228769	0	228769	intron_variant	0	0.20	4e-06	5.39794000867204		0.07	[0.04-0.10] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	6q25.1	6	151769572	ESR1	ESR1			ENSG00000091831	NA	NA	rs2504063-A	rs2504063	0	2504063	intron_variant	0	0.40	6e-11	10.2218487496164		0.08	[0.06-0.10] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	11q13.2	11	68424878	LRP5	LRP5			ENSG00000162337	NA	NA	rs599083-G	rs599083	0	599083	intron_variant	0	0.31	5e-08	7.30102999566398		0.07	[0.05-0.09] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	18q21.33	18	62387624	TNFRSF11A	TNFRSF11A			ENSG00000141655	NA	NA	rs884205-A	rs884205	0	884205	3_prime_UTR_variant	0	0.27	9e-09	8.04575749056067		0.08	[0.05-0.11] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	7q21.3	7	96488606	FLJ42280	SEM1			ENSG00000127922	NA	NA	rs4729260-G	rs4729260	0	4729260	intron_variant	0	0.32	2e-10	9.69897000433602		0.08	[0.05-0.11] s.d. decrease	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	11p13	11	31189224	DCDC5	DCDC1			ENSG00000170959	NA	NA	rs16921914-A	rs16921914	0	16921914	intron_variant	0	0.27	2e-09	8.69897000433602		0.08	[0.05-0.11] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	4q22.1	4	87854091	MEPE	MEPE - HSP90AB3P	ENSG00000152595	ENSG00000183199		7274	37752	rs1471403-T	rs1471403	0	1471403	intergenic_variant	1	0.34	2e-08	7.69897000433602		0.07	[0.05-0.09] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	2p16.2	2	54457420	SPTBN1	SPTBN1			ENSG00000115306	NA	NA	rs11898505-A	rs11898505	0	11898505	intron_variant	0	0.34	2e-08	7.69897000433602		0.07	[0.05-0.09] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-10-16	19801982	Rivadeneira F	2009-10-04	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19801982	Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.	Bone mineral density (spine)	19,195 European ancestry individuals	NA	8q24.12	8	118995181	TNFRSF11B	AC107953.1 - COLEC10	ENSG00000254247	ENSG00000184374		12306	271	rs2062377-T	rs2062377	0	2062377	regulatory_region_variant	1	0.44	4e-16	15.397940008672		0.09	[0.07-0.11] s.d. increase	Affymetrix, Illumina [2543686] (imputed)	N
2009-12-29	20031577	Danik JS	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031577	Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.	Fibrinogen	17,686 European ancestry female individuals	NA	5q31.1	5	132335969	IRF1, SLC22A5, SLC22A4	MIR3936HG, SLC22A4			ENSG00000233006, ENSG00000197208	NA	NA	rs10479002-C	rs10479002	1	12777	synonymous_variant	0	0.04	1e-06	6		9.51	[NR] mg/dl increase	Illumina [337343]	N
2009-12-29	20031577	Danik JS	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031577	Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.	Fibrinogen	17,686 European ancestry female individuals	NA	1q21.3	1	154454494	IL6R	IL6R			ENSG00000160712	NA	NA	rs8192284-C	rs8192284	1	2228145	missense_variant	0	0.40	2e-11	10.698970004336		5.3	[NR] mg/dl decrease	Illumina [337343]	N
2009-12-29	20031577	Danik JS	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031577	Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.	Fibrinogen	17,686 European ancestry female individuals	NA	2q34	2	210675783	CPS1	CPS1			ENSG00000021826	NA	NA	rs7422339-A	rs7422339	1	1047891	missense_variant	0	0.31	9e-09	8.04575749056067		4.84	[NR] mg/dl decrease	Illumina [337343]	N
2009-12-29	20031577	Danik JS	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031577	Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.	Fibrinogen	17,686 European ancestry female individuals	NA	17q25.1	17	74703694	CD300LF, SLC9A3R1, NAT9	RAB37, CD300LF			ENSG00000172794, ENSG00000186074	NA	NA	rs10512597-A	rs10512597	0	10512597	intron_variant	0	0.18	8e-11	10.0969100130081		6.45	[NR] mg/dl decrease	Illumina [337343]	N
2009-12-29	20031577	Danik JS	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031577	Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.	Fibrinogen	17,686 European ancestry female individuals	NA	5q31.1	5	132408882	IRF1, SLC22A5, SLC22A4	SLC22A5 - C5orf56	ENSG00000197375	ENSG00000197536		13268	1754	rs1016988-G	rs1016988	0	1016988	intergenic_variant	1	0.20	1e-12	12		6.84	[NR] mg/dl decrease	Illumina [337343]	N
2009-12-29	20031577	Danik JS	2009-04-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031577	Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.	Fibrinogen	17,686 European ancestry female individuals	NA	4q31.3	4	154567669	FGB, FGA, FGG	FGB			ENSG00000171564	NA	NA	rs6056-A	rs6056	0	6056	synonymous_variant	0	0.18	8e-39	38.0969100130081		12.94	[NR] mg/dl increase	Illumina [337343]	N
2008-06-26	18535201	Cooper GM	2008-06-05	Blood	www.ncbi.nlm.nih.gov/pubmed/18535201	A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.	Warfarin maintenance dose	181 European ancestry individuals	374 European ancestry individuals	16p11.2	16	31036758	VKORC1	STX4			ENSG00000103496	NA	NA	rs10871454-?	rs10871454	0	10871454	intron_variant	0	NR	5e-34	33.301029995664		NA		Illumina [538629]	N
2008-06-26	18535201	Cooper GM	2008-06-05	Blood	www.ncbi.nlm.nih.gov/pubmed/18535201	A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.	Warfarin maintenance dose	181 European ancestry individuals	374 European ancestry individuals	10q23.33	10	94947445	CYP2C9	CYP2C9			ENSG00000138109	NA	NA	rs4086116-?	rs4086116	0	4086116	intron_variant	0	NR	6e-12	11.2218487496164		NA		Illumina [538629]	N
2008-06-26	18535201	Cooper GM	2008-06-05	Blood	www.ncbi.nlm.nih.gov/pubmed/18535201	A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose.	Warfarin maintenance dose	181 European ancestry individuals	374 European ancestry individuals	12p13.33	12	2620466	CACNA1C	CACNA1C, CACNA1C			ENSG00000151067, ENSG00000285479	NA	NA	rs216013-?	rs216013	0	216013	intron_variant	0	NR	9e-07	6.04575749056067		NA		Illumina [538629]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	8q22.3	8	100829318	intergenic	RPS20P23 - RNU4-83P	ENSG00000242399	ENSG00000222795		52453	2410	rs3108919-C	rs3108919	0	3108919	regulatory_region_variant	1	0.27	4e-06	5.39794000867204		2.13	[1.56-2.91]	Illumina [291119]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	2q12.1	2	105281283	TGFBRAP1	TGFBRAP1			ENSG00000135966	NA	NA	rs1020064-G	rs1020064	0	1020064	intron_variant	0	0.77	7e-06	5.15490195998574		2.94	[1.75-5.00]	Illumina [291119]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	12p12.1	12	24241438	SOX5	SOX5-AS1, SOX5			ENSG00000256120, ENSG00000134532	NA	NA	rs1522232-C	rs1522232	0	1522232	intron_variant	0	0.52	2e-06	5.69897000433602		2.22	[1.59-3.13]	Illumina [291119]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	1p13.3	1	107035210	intergenic	LINC01661 - PRMT6	ENSG00000237460	ENSG00000198890		169894	21464	rs4118325-G	rs4118325	0	4118325	intergenic_variant	1	0.81	6e-07	6.22184874961636		4.17	[2.17-8.33]	Illumina [291119]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	1q23.3	1	165439858	RXRG	RXRG			ENSG00000143171	NA	NA	rs10800098-A	rs10800098	0	10800098	intron_variant	0	0.05	4e-06	5.39794000867204		3.29	[2.08-5.20]	Illumina [291119]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	9p23	9	13007130	intergenic	AL161449.2			ENSG00000285637	NA	NA	rs1360517-A	rs1360517	0	1360517	intron_variant	0	0.06	3e-06	5.52287874528034		3.09	[2.00-4.78]	Illumina [291119]	N
2009-09-30	19754311	Le Clerc S	2009-09-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/19754311	Genomewide association study of a rapid progression cohort identifies new susceptibility alleles for AIDS (ANRS Genomewide Association Study 03).	AIDS	85 European ancestry cases, 2,049 European ancestry controls	NA	9p22.3	9	14446003	NR	AL137017.1			ENSG00000287708	NA	NA	rs1556032-C	rs1556032	0	1556032	intron_variant	0	0.49	9e-06	5.04575749056067		2.05	[1.48-2.84]	Illumina [291119]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	11p14.2	11	26583784	MUC15	ANO3			ENSG00000134343	NA	NA	rs12295638-C	rs12295638	0	12295638	intron_variant	0	0.10	4e-06	5.39794000867204		1.49	[1.26-1.77]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	3p24.2	3	25518740	RARB	RARB			ENSG00000077092	NA	NA	rs1435703-T	rs1435703	0	1435703	intron_variant	0	0.06	4e-06	5.39794000867204		1.66	[1.34-2.06]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	2p16.1	2	54929493	RTN4	EML6			ENSG00000214595	NA	NA	rs6726292-G	rs6726292	0	6726292	intron_variant	0	0.73	1e-06	6		1.39	[1.22-1.59]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	6p21.31	6	33794465	MLN	LEMD2 - MLN	ENSG00000161904	ENSG00000096395		5335	208	rs2274459-A	rs2274459	0	2274459	regulatory_region_variant	1	0.17	6e-06	5.22184874961636		1.38	[1.20-1.58]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	6p21.31	6	33656956	ITPR3	ITPR3			ENSG00000096433	NA	NA	rs999943-T	rs999943	0	999943	intron_variant	0	0.72	1e-06	6		1.37	[1.20-1.56]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	16q12.2	16	53791576	FTO	FTO			ENSG00000140718	NA	NA	rs9941349-T	rs9941349	0	9941349	intron_variant	0	0.43	6e-12	11.2218487496164		1.48	[1.33-1.66]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	4q26	4	117171981	TRAM1L1	TRAM1L1 - AC107399.1	ENSG00000174599	ENSG00000223605		86405	77943	rs10433903-T	rs10433903	0	10433903	intergenic_variant	1	0.66	3e-06	5.52287874528034		1.33	[1.19-1.52]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	20p12.1	20	15355108	C20orf133	MACROD2			ENSG00000172264	NA	NA	rs6110577-C	rs6110577	0	6110577	intron_variant	0	0.16	5e-06	5.30102999566398		1.4	[1.21-1.61]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	2q33.3	2	205971888	FLJ20309	PPIAP68 - AC007679.1	ENSG00000213739	ENSG00000225610		21743	17697	rs7603514-A	rs7603514	0	7603514	intergenic_variant	1	0.20	8e-06	5.09691001300806		1.36	[1.19-1.56]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	3p24.3	3	16366982	RAFTLIN	AC090948.4, RFTN1			ENSG00000287377, ENSG00000131378	NA	NA	rs12635698-C	rs12635698	0	12635698	intron_variant	0	0.15	5e-06	5.30102999566398		1.41	[1.21-1.63]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	10q22.1	10	70572684	PRF1	PALD1 - PRF1	ENSG00000107719	ENSG00000180644		4234	24664	rs10999409-T	rs10999409	0	10999409	TF_binding_site_variant	1	0.45	5e-06	5.30102999566398		1.3	[1.16-1.45]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	10p11.21	10	37693169	ZNF248	MTRNR2L7 - AL132657.1	ENSG00000256892	ENSG00000226578		90195	82202	rs7474896-T	rs7474896	0	7474896	intergenic_variant	1	0.14	9e-07	6.04575749056067		1.46	[1.25-1.69]	Illumina [457251]	N
2009-07-01	19553259	Cotsapas C	2009-06-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19553259	Common body mass index-associated variants confer risk of extreme obesity.	Obesity (extreme)	775 European ancestry cases, 3,197 European ancestry controls	NA	5q23.3	5	128363682	FBN2	FBN2			ENSG00000138829	NA	NA	rs374748-G	rs374748	0	374748	intron_variant	0	0.11	4e-06	5.39794000867204		1.47	[1.25-1.73]	Illumina [457251]	N
2009-08-12	19609347	Adeyemo A	2009-07-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19609347	A genome-wide association study of hypertension and blood pressure in African Americans.	Hypertension	509 African American cases, 508 African American controls	366 West African ancestry cases, 614 West African ancestry controls	4q23	4	99401288	ADH7	ADH1B - ADH7	ENSG00000196616	ENSG00000196344		48528	10973	rs991316-T	rs991316	0	991316	intergenic_variant	1	0.45	5e-06	5.30102999566398		1.62	[NR]	Affymetrix [808465]	N
2009-08-12	19609347	Adeyemo A	2009-07-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19609347	A genome-wide association study of hypertension and blood pressure in African Americans.	Hypertension	509 African American cases, 508 African American controls	366 West African ancestry cases, 614 West African ancestry controls	15q21.3	15	57921216	ALDH1A2	POLR2M - ALDH1A2	ENSG00000255529	ENSG00000128918		138454	32208	rs1550576-?	rs1550576	0	1550576	regulatory_region_variant	1	0.86	3e-06	5.52287874528034		1.92	[NR]	Affymetrix [808465]	N
2008-06-27	18451265	Bouatia-Naji N	2008-06-19	Science	www.ncbi.nlm.nih.gov/pubmed/18451265	A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.	Fasting plasma glucose	654 European ancestry individuals	9,353 European ancestry individuals	2q31.1	2	168906638	G6PC2	SPC25, SPC25, G6PC2, G6PC2			ENSG00000152253, ENSG00000277909, ENSG00000152254, ENSG00000278373	NA	NA	rs560887-A	rs560887	0	560887	intron_variant	0	0.30	4e-23	22.397940008672		0.06	[0.05-0.08] mmol/l decrease	Illumina [392935]	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	1p13.1	1	116561593	CD58	CD58			ENSG00000116815	NA	NA	rs2300747-A	rs2300747	0	2300747	intron_variant	0	0.88	3e-10	9.52287874528034		1.3	[1.14-1.47]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	6p21.32	6	32445274	HLA-DRB1	HLA-DRA - HLA-DRB9	ENSG00000234794	ENSG00000226035		228	14547	rs3135388-A	rs3135388	0	3135388	intergenic_variant	1	0.22	4e-225	224.397940008672		2.75	[2.46-3.07]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	6p22.1	6	29737882	HLA-B	HLA-F, HLA-F, HLA-F, HLA-F, HLA-F, HLA-F, HLA-F, HLA-F-AS1, HLA-F-AS1, HLA-F-AS1, HLA-F-AS1, HLA-F-AS1, HLA-F-AS1			ENSG00000235220, ENSG00000204642, ENSG00000137403, ENSG00000237508, ENSG00000234487, ENSG00000229698, ENSG00000206509, ENSG00000226378, ENSG00000214922, ENSG00000206446, ENSG00000230017, ENSG00000230545, ENSG00000206508	NA	NA	rs2523393-A	rs2523393	0	2523393	non_coding_transcript_exon_variant	0	0.59	1e-17	17		1.28	[1.18-1.39]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	3q25.33	3	159981157	IL12A	IL12A-AS1			ENSG00000244040	NA	NA	rs4680534-C	rs4680534	0	4680534	intron_variant	0	0.37	6e-06	5.22184874961636		1.12	[1.02-1.22]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	10p15.1	10	6057082	IL2RA	IL2RA			ENSG00000134460	NA	NA	rs2104286-T	rs2104286	0	2104286	intron_variant	0	0.76	9e-08	7.04575749056067		1.15	[1.04-1.27]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	12p13.31	12	6333477	TNFRSF1A	TNFRSF1A			ENSG00000067182	NA	NA	rs4149584-T	rs4149584	0	4149584	missense_variant	0	0.022	5e-06	5.30102999566398		1.58	[1.15-2.17]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	2q22.1	2	136218685	CXCR4	HNRNPKP2 - AC112255.1	ENSG00000227347	ENSG00000279024		18182	12068	rs882300-C	rs882300	0	882300	intergenic_variant	1	0.61	1e-07	7		1.19	[1.09-1.30]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	16p13.13	16	11072831	CLEC16A	CLEC16A			ENSG00000038532	NA	NA	rs11865121-C	rs11865121	0	11865121	intron_variant	0	0.69	2e-07	6.69897000433602		1.15	[1.04-1.25]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	5p13.2	5	35874473	IL7R	IL7R			ENSG00000168685	NA	NA	rs6897932-C	rs6897932	0	6897932	missense_variant	0	0.75	2e-06	5.69897000433602		1.12	[1.02-1.23]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	16q24.1	16	85984057	IRF8	AC092723.4, AC092723.1			ENSG00000285040, ENSG00000269667	NA	NA	rs17445836-G	rs17445836	0	17445836	intron_variant	0	0.81	4e-09	8.39794000867204		1.25	[1.12-1.39]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	11q12.2	11	60993140	CD6	CD6			ENSG00000013725	NA	NA	rs17824933-G	rs17824933	0	17824933	intron_variant	0	0.25	4e-09	8.39794000867204		1.18	[1.07-1.30]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	5p13.1	5	40424324	PTGER4	AC093277.1			ENSG00000283286	NA	NA	rs6896969-C	rs6896969	0	6896969	intron_variant	0	0.62	2e-07	6.69897000433602		1.1	[1.01-1.20]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	12q24.31	12	123172178	MPHOSPH9	MPHOSPH9			ENSG00000051825	NA	NA	rs1790100-G	rs1790100	0	1790100	intron_variant	0	0.24	7e-07	6.15490195998574		1.11	[1.00-1.22]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	10q22.3	10	79276250	ZMIZ1	ZMIZ1			ENSG00000108175	NA	NA	rs1250540-G	rs1250540	0	1250540	intron_variant	0	0.35	2e-06	5.69897000433602		1.12	[1.02-1.22]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-29	19525953	De Jager PL	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525953	Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.	Multiple sclerosis	2,624 European ancestry cases, 7,220 European ancestry controls	2,215 European ancestry cases, 2,116 European ancestry controls	12p13.31	12	6330843	TNFRSF1A	TNFRSF1A			ENSG00000067182	NA	NA	rs1800693-C	rs1800693	0	1800693	non_coding_transcript_exon_variant	0	0.45	2e-11	10.698970004336		1.2	[1.10-1.31]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	3q25.33	3	160011091	IL12A	IL12A-AS1			ENSG00000244040	NA	NA	rs6441286-G	rs6441286	0	6441286	intron_variant	0	0.39	2e-14	13.698970004336		1.54	[1.38-1.72]	Illumina [305724]	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	1p31.3	1	67356694	IL12RB2	IL12RB2			ENSG00000081985	NA	NA	rs3790567-A	rs3790567	0	3790567	intron_variant	0	0.24	3e-11	10.5228787452803		1.51	[1.33-1.70]	Illumina [305724]	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	7q32.1	7	128954129	IRF5-TNPO3	AC025594.2 - TNPO3	ENSG00000275106	ENSG00000064419		813	51	rs10488631-G	rs10488631	0	10488631	intergenic_variant	1	NR	2e-07	6.69897000433602		1.52	[1.30-1.78]	Illumina [305724]	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	17q12	17	39766006	IKZF3	IKZF3			ENSG00000161405	NA	NA	rs907092-A	rs907092	0	907092	synonymous_variant	0	0.45	8e-06	5.09691001300806		1.29	[1.15-1.44]	Illumina [305724]	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	3q25.33	3	160623108	ARF7	RPL6P8 - ARL14	ENSG00000242285	ENSG00000179674		37321	54052	rs4679904-G	rs4679904	0	4679904	intergenic_variant	1	0.72	1e-06	6		1.38	[1.21-1.57]	Illumina [305724]	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	6p21.32	6;6;6;6	32353777;32687441;32421871;32697183	c6orf10, HLA-DQB1, BTNL2	TSBP1; TSBP1-AS1; HLA-DQB1 - MTCO3P1; TSBP1-AS1 - HLA-DRA; HLA-DQB1 - MTCO3P1				NA	NA	rs2395148-A; rs2856683-C; rs3135363-A; rs9357152-A	rs2395148; rs2856683; rs3135363; rs9357152	0	NA	intron_variant; regulatory_region_variant; intergenic_variant; regulatory_region_variant	NA	0.01	1e-10	10		NA		Illumina [305724]	N
2009-06-21	19458352	Hirschfield GM	2009-05-20	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/19458352	Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.	Primary biliary cholangitis	505 European ancestry cases, 1,507 European ancestry controls	526 European ancestry cases, 1,206 European ancestry controls	6p21.32	6;6;6;6	32353777;32687441;32421871;32697183	c6orf10, HLA-DQB1, BTNL2	TSBP1; TSBP1-AS1; HLA-DQB1 - MTCO3P1; TSBP1-AS1 - HLA-DRA; HLA-DQB1 - MTCO3P1				NA	NA	rs2395148-C; rs2856683-C; rs3135363-A; rs9357152-A	rs2395148; rs2856683; rs3135363; rs9357152	0	NA	intron_variant; regulatory_region_variant; intergenic_variant; regulatory_region_variant	NA	0.2	7e-10	9.15490195998574		NA		Illumina [305724]	N
2009-09-04	19664746	Tse KP	2009-08-05	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19664746	Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.	Nasopharyngeal carcinoma	277 Han Chinese ancestry cases, 285 Han Chinese ancestry controls	635 Han Chinese ancestry cases, 1,640 Han Chinese ancestry controls	6p22.1	6	29950322	HLA-A	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144		4438	6274	rs2517713-A	rs2517713	0	2517713	intron_variant	1	0.62	4e-20	19.397940008672		1.88	[1.65-2.15]	Illumina [480365]	N
2009-09-04	19664746	Tse KP	2009-08-05	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19664746	Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.	Nasopharyngeal carcinoma	277 Han Chinese ancestry cases, 285 Han Chinese ancestry controls	635 Han Chinese ancestry cases, 1,640 Han Chinese ancestry controls	6p22.1	6	29702484	HLA-F	ZFP57 - ZDHHC20P1	ENSG00000232099	ENSG00000228371		21374	5641	rs3129055-G	rs3129055	0	3129055	regulatory_region_variant	1	0.31	7e-11	10.1549019599857		1.51	[1.34-1.71]	Illumina [480365]	N
2009-09-04	19664746	Tse KP	2009-08-05	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19664746	Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3.	Nasopharyngeal carcinoma	277 Han Chinese ancestry cases, 285 Han Chinese ancestry controls	635 Han Chinese ancestry cases, 1,640 Han Chinese ancestry controls	6p22.1	6	29643654	GABBR1	SUMO2P1 - MOG	ENSG00000228130	ENSG00000236561		7311	13348	rs29232-A	rs29232	0	29232	intergenic_variant	1	0.46	9e-17	16.0457574905607		1.67	[1.48-1.88]	Illumina [480365]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	20p12.2	20	11176363	intergenic	C20orf187 - AL049649.1	ENSG00000125899	ENSG00000230990		146908	57807	rs6040399-T	rs6040399	0	6040399	intergenic_variant	1	NR	1e-06	6	(AA - Dizziness)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	4q35.2	4	186417181	intergenic	F11-AS1			ENSG00000251165	NA	NA	rs11935103-T	rs11935103	0	11935103	intron_variant	0	0.262	1e-06	6	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	16p13.12	16	13563028	intergenic	U91319.1			ENSG00000262801	NA	NA	rs2903308-A	rs2903308	0	2903308	non_coding_transcript_exon_variant	0	0.461	2e-06	5.69897000433602	(EA + AA - Overall tolerability)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	3p14.2	3	59935294	FHIT	FHIT			ENSG00000189283	NA	NA	rs4502542-T	rs4502542	0	4502542	intron_variant	0	0.017	2e-06	5.69897000433602	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	13q31.1	13	83556097	intergenic	RNU6-67P - AL353688.1	ENSG00000222791	ENSG00000286446		257930	94152	rs6563353-A	rs6563353	0	6563353	intergenic_variant	1	0.177	2e-06	5.69897000433602	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	13q33.2	13	105154672	intergenic	RPL7P45 - AL138954.1	ENSG00000225823	ENSG00000286929		339603	256144	rs16965962-T	rs16965962	0	16965962	intergenic_variant	1	0.03	3e-07	6.52287874528034	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	Xq23	X	117088295	intergenic	SETP8 - AC005002.2	ENSG00000213526	ENSG00000238066		124619	309643	rs6646773-C	rs6646773	0	6646773	intergenic_variant	1	0.076	1e-06	6	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	3q27.3	3	187696203	RPT2	SST - RTP2	ENSG00000157005	ENSG00000198471		25809	2056	rs6764050-G	rs6764050	0	6764050	intergenic_variant	1	0.023	9e-07	6.04575749056067	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	18p11.31	18	6941109	LAMA1	RNU6-916P - LAMA1	ENSG00000251897	ENSG00000101680		4089	633	rs4398173-G	rs4398173	0	4398173	intergenic_variant	1	NR	4e-06	5.39794000867204	(EA - Overall tolerability)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	13q33.2	13	105154672	intergenic	RPL7P45 - AL138954.1	ENSG00000225823	ENSG00000286929		339603	256144	rs16965962-T	rs16965962	0	16965962	intergenic_variant	1	NR	3e-07	6.52287874528034	(AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	4q35.2	4	186417181	intergenic	F11-AS1			ENSG00000251165	NA	NA	rs11935103-T	rs11935103	0	11935103	intron_variant	0	NR	2e-06	5.69897000433602	(EA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	5p13.1	5	38452792	EGFLAM	EGFLAM			ENSG00000164318	NA	NA	rs7715172-G	rs7715172	0	7715172	intron_variant	0	0.071	3e-06	5.52287874528034	(EA + AA - GSE)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	7q22.1	7	101472713	EMID2	COL26A1			ENSG00000160963	NA	NA	rs17135437-A	rs17135437	0	17135437	intron_variant	0	0.019	3e-08	7.52287874528034	(EA + AA - Vision\hearing)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	18p11.31	18	6941663	LAMA1	RNU6-916P - LAMA1	ENSG00000251897	ENSG00000101680		4643	79	rs3810046-T	rs3810046	0	3810046	regulatory_region_variant	1	0.456	5e-07	6.30102999566398	(EA + AA - Overall tolerability)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	2q33.1	2	200783916	AOX2P	AOX2P, AC007163.1			ENSG00000243478, ENSG00000230408	NA	NA	rs13430864-G	rs13430864	0	13430864	intron_variant	0	0.04	5e-07	6.30102999566398	(EA + AA - Dizziness)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	20p12.2	20	11176363	intergenic	C20orf187 - AL049649.1	ENSG00000125899	ENSG00000230990		146908	57807	rs6040399-T	rs6040399	0	6040399	intergenic_variant	1	0.308	7e-07	6.15490195998574	(EA + AA - Dizziness)	NA		Affymetrix [421789]	N
2012-09-21	22760553	Adkins DE	2012-07-03	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22760553	Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.	Response to citalopram treatment	1,392 European ancestry depression cases, 264 African American depression cases, 106 depression cases	NA	7q22.1	7	101472713	EMID2	COL26A1			ENSG00000160963	NA	NA	rs17135437-A	rs17135437	0	17135437	intron_variant	0	NR	3e-06	5.52287874528034	(AA - Vision\hearing)	NA		Affymetrix [421789]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	9q21.2	9	76793228	PRUNE2	PRUNE2, PCA3			ENSG00000106772, ENSG00000225937	NA	NA	rs10781380-?	rs10781380	0	10781380	intron_variant	0	NR	7e-07	6.15490195998574		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	5q21.3	5	107646859	EFNA5	EFNA5			ENSG00000184349	NA	NA	rs10074258-?	rs10074258	0	10074258	intron_variant	0	NR	2e-07	6.69897000433602		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	7p12.2	7	50273756	IKZF1	AC020743.2 - AC020743.3	ENSG00000231681	ENSG00000235620		10762	1034	rs10276619-?	rs10276619	0	10276619	intergenic_variant	1	NR	3e-06	5.52287874528034		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	7q21.11	7	78546660	MAGI2	MAGI2			ENSG00000187391	NA	NA	rs11525066-?	rs11525066	0	11525066	intron_variant	0	NR	3e-06	5.52287874528034		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	8q24.12	8	119212566	MAL2	MAL2			ENSG00000147676	NA	NA	rs1364705-?	rs1364705	0	1364705	intron_variant	0	NR	9e-06	5.04575749056067		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	12q14.3	12	67235051	CAND1	RAB11AP2 - GGTA2P	ENSG00000255976	ENSG00000237766		102846	30791	rs1082714-?	rs1082714	0	1082714	intergenic_variant	1	NR	5e-06	5.30102999566398		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	9q21.31	9	81400122	RP11-232A1.1	AL138749.1 - RPS20P25	ENSG00000226798	ENSG00000228375		528827	10157	rs10867752-?	rs10867752	0	10867752	intergenic_variant	1	NR	3e-06	5.52287874528034		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	12q13.11	12	46092055	ARID2, SFRS2IP	AC084878.1 - SLC38A1	ENSG00000239397	ENSG00000111371		87370	91008	rs1373549-?	rs1373549	0	1373549	intergenic_variant	1	NR	8e-06	5.09691001300806		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	20q11.23	20	37137934	C20orf132	MROH8			ENSG00000101353	NA	NA	rs8115854-?	rs8115854	0	8115854	missense_variant	0	NR	2e-06	5.69897000433602		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	20q11.23	20	37181380	RPN2	RPN2			ENSG00000118705	NA	NA	rs6031882-?	rs6031882	0	6031882	intron_variant	0	NR	6e-06	5.22184874961636		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	21q21.1	21	20405418	FDPSP	FDPSP6 - KRT18P2	ENSG00000233676	ENSG00000234439		16573	19531	rs1888414-?	rs1888414	0	1888414	intergenic_variant	1	NR	2e-07	6.69897000433602		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	5q14.1	5	78964065	ARSB	ARSB			ENSG00000113273	NA	NA	rs337847-?	rs337847	0	337847	intron_variant	0	NR	7e-06	5.15490195998574		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	14q22.1	14	51766558	FRMD6	AL079307.1			ENSG00000258535	NA	NA	rs11626056-?	rs11626056	0	11626056	non_coding_transcript_exon_variant	0	NR	1e-06	6		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	7p21.3	7	9499649	intergenic	AC004852.2 - GAPDHP68	ENSG00000278254	ENSG00000233876		309792	115329	rs9918508-?	rs9918508	0	9918508	intergenic_variant	1	NR	8e-06	5.09691001300806		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	20q13.31	20	57615578	ZBP1	ZBP1			ENSG00000124256	NA	NA	rs2073145-?	rs2073145	0	2073145	missense_variant	0	NR	2e-06	5.69897000433602		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	13q31.1	13	86590602	intergenic	AL445207.1 - TXNL1P1	ENSG00000287880	ENSG00000231879		127868	134898	rs4773460-?	rs4773460	0	4773460	intergenic_variant	1	NR	2e-06	5.69897000433602		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	11q24.3	11	128336515	intergenic	LINC02098 - ETS1	ENSG00000272575	ENSG00000134954		95074	122246	rs6590322-?	rs6590322	0	6590322	regulatory_region_variant	1	NR	9e-06	5.04575749056067		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	1q21.3	1	153507522	S100A5	RN7SL44P - BX470102.1	ENSG00000263841	ENSG00000238279		6758	26081	rs4845552-?	rs4845552	0	4845552	intergenic_variant	1	NR	6e-06	5.22184874961636		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	5p15.1	5	17148802	NR	BASP1-AS1, BASP1			ENSG00000215196, ENSG00000176788	NA	NA	rs682748-?	rs682748	0	682748	intron_variant	0	NR	8e-06	5.09691001300806		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	5p14.1	5	25760570	intergenic	AC022418.1 - MSNP1	ENSG00000279869	ENSG00000251593		43855	148933	rs7727656-?	rs7727656	0	7727656	intergenic_variant	1	NR	8e-06	5.09691001300806		NA		Illumina [516645]	N
2009-09-09	19668339	Potkin SG	2009-08-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19668339	Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.	Hippocampal atrophy	162 European ancestry cases, 192 European ancestry controls, 7 African American cases, 14 African American controls, 1 Asian ancestry cases, 3 Asian ancestry controls, 2 cases	NA	5q14.1	5	78335030	SCAMP1, LHFPL2	Y_RNA - SCAMP1-AS1	ENSG00000265852	ENSG00000245556		17893	7335	rs6881634-?	rs6881634	0	6881634	regulatory_region_variant	1	NR	2e-06	5.69897000433602		NA		Illumina [516645]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	20p12.3	20	5954739	MCM8	AL035461.3, MCM8			ENSG00000286235, ENSG00000125885	NA	NA	rs236114-A	rs236114	0	236114	intron_variant	0	0.21	1e-10	10		0.5	[0.34-0.65] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	11q25	11	133697090	NR	AP004606.1 - LINC02743	ENSG00000287068	ENSG00000255258		147224	86581	rs4397868-?	rs4397868	0	4397868	intergenic_variant	1	NR	3e-07	6.52287874528034		0.4	[0.25-0.55] years decrease	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	2q23.3	2	149840634	NR	AC007364.1, LINC01931			ENSG00000231969, ENSG00000162947	NA	NA	rs11889862-?	rs11889862	0	11889862	intron_variant	0	NR	2e-06	5.69897000433602		0.36	[0.21-0.51] years decrease	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	7q22.3	7	106855364	NR	LINC02577 - PIK3CG	ENSG00000228742	ENSG00000105851		16884	9914	rs17153527-?	rs17153527	0	17153527	intergenic_variant	1	NR	4e-07	6.39794000867204		0.51	[0.31-0.71] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	20p12.3	20	6054582	NR	LRRN4 - AL118505.1	ENSG00000125872	ENSG00000278192		522	11384	rs2326679-?	rs2326679	0	2326679	regulatory_region_variant	1	NR	2e-06	5.69897000433602		0.32	[0.19-0.45] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	19q13.42	19	55308477	BRSK1, TMEM224, SUV420H2	BRSK1			ENSG00000160469	NA	NA	rs1172822-T	rs1172822	0	1172822	intron_variant	0	0.39	6e-11	10.2218487496164		0.39	[0.27-0.51] years decrease	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	16q24.2	16	87957445	NR	BANP			ENSG00000172530	NA	NA	rs4843747-?	rs4843747	0	4843747	intron_variant	0	NR	2e-07	6.69897000433602		0.39	[0.24-0.54] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	8p11.23	8	37829231	NR	ADGRA2			ENSG00000020181	NA	NA	rs6468442-?	rs6468442	0	6468442	intron_variant	0	NR	3e-07	6.52287874528034		0.39	[0.24-0.54] years decrease	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	6p21.33	6	31870936	NR	SLC44A4, SLC44A4, SLC44A4, SLC44A4, SLC44A4, SLC44A4			ENSG00000232180, ENSG00000231479, ENSG00000204385, ENSG00000228263, ENSG00000229077, ENSG00000235336	NA	NA	rs494620-?	rs494620	0	494620	stop_gained	0	NR	5e-07	6.30102999566398		0.3	[0.18-0.42] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	9q21.31	9	79730966	NR	TLE4 - AL161912.3	ENSG00000106829	ENSG00000270691		4084	119905	rs2151145-?	rs2151145	0	2151145	intergenic_variant	1	NR	1e-07	7		0.41	[0.26-0.56] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	14q32.31	14	101988596	NR	DYNC1H1			ENSG00000197102	NA	NA	rs4906172-?	rs4906172	0	4906172	intron_variant	0	NR	3e-06	5.52287874528034		0.36	[0.21-0.51] years decrease	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	3q26.2	3	170776620	NR	SLC7A14-AS1, AC026316.4			ENSG00000285051, ENSG00000285218	NA	NA	rs4955755-?	rs4955755	0	4955755	intron_variant	0	NR	7e-07	6.15490195998574		0.34	[0.21-0.47] years increase	Illumina [315418]	N
2009-05-28	19448619	Stolk L	2009-05-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19448619	Loci at chromosomes 13, 19 and 20 influence age at natural menopause.	Menopause (age at onset)	2,979 European ancestry female individuals	2,560 European ancestry female individuals	13q34	13	111568950	ARHGEF7, LOC121793	TEX29 - AL359649.1	ENSG00000153495	ENSG00000204398		224701	19251	rs7333181-A	rs7333181	0	7333181	intergenic_variant	1	0.12	3e-08	7.52287874528034		0.52	[0.34-0.70] years increase	Illumina [315418]	N
2009-06-15	19483685	Daly AK	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483685	HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.	Drug-induced liver injury (flucloxacillin)	58 European ancestry cases, 282 European ancestry controls	NA	3q27.3	3	186933001	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs10937275-?	rs10937275	0	10937275	intron_variant	0	0.09	1e-08	8	(B*5701 positive)	4.1	[NR]	Illumina [866399]	N
2009-06-15	19483685	Daly AK	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483685	HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.	Drug-induced liver injury (flucloxacillin)	58 European ancestry cases, 282 European ancestry controls	NA	9p21.2	9	26614849	C9org82	AL353753.1 - AL442639.1	ENSG00000276759	ENSG00000279256		496441	27848	rs10812428-?	rs10812428	0	10812428	intergenic_variant	1	0.31	1e-06	6		2.85	[NR]	Illumina [866399]	N
2009-06-15	19483685	Daly AK	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483685	HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.	Drug-induced liver injury (flucloxacillin)	58 European ancestry cases, 282 European ancestry controls	NA	3q11.2	3	98315682	OR5H2	AC117473.1			ENSG00000251088	NA	NA	rs1497546-?	rs1497546	0	1497546	intron_variant	0	0.02	2e-07	6.69897000433602		6.57	[NR]	Illumina [866399]	N
2009-06-15	19483685	Daly AK	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483685	HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.	Drug-induced liver injury (flucloxacillin)	58 European ancestry cases, 282 European ancestry controls	NA	6p21.33	6	31464003	HCP5, HLA-B	HCP5			ENSG00000206337	NA	NA	rs2395029-?	rs2395029	0	2395029	non_coding_transcript_exon_variant	0	0.05	9e-33	32.0457574905607		45	[19.4-105]	Illumina [866399]	N
2009-06-15	19483685	Daly AK	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483685	HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.	Drug-induced liver injury (flucloxacillin)	58 European ancestry cases, 282 European ancestry controls	NA	12q12	12	38349706	ALG10B	ALG10B - AC087897.1	ENSG00000175548	ENSG00000257645		19985	183189	rs6582630-?	rs6582630	0	6582630	intergenic_variant	1	0.38	1e-06	6		2.82	[NR]	Illumina [866399]	N
2009-06-15	19483685	Daly AK	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483685	HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.	Drug-induced liver injury (flucloxacillin)	58 European ancestry cases, 282 European ancestry controls	NA	15q26.2	15	94396279	MCTP2	MCTP2			ENSG00000140563	NA	NA	rs4984390-?	rs4984390	0	4984390	intron_variant	0	0.41	4e-06	5.39794000867204		3.27	[NR]	Illumina [866399]	N
2009-09-04	19656524	Grant SF	2009-08-03	J Pediatr	www.ncbi.nlm.nih.gov/pubmed/19656524	A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24.	Orofacial clefts	111 European ancestry cases, 5,951 European ancestry controls	NA	18q22.3	18	71771837	intergenic	LINC01899			ENSG00000265352	NA	NA	rs17085106-?	rs17085106	0	17085106	intron_variant	0	0.018	4e-08	7.39794000867204		4.07	[2.37-7.00]	Illumina [495858]	N
2009-09-04	19656524	Grant SF	2009-08-03	J Pediatr	www.ncbi.nlm.nih.gov/pubmed/19656524	A genome-wide association study identifies a locus for nonsyndromic cleft lip with or without cleft palate on 8q24.	Orofacial clefts	111 European ancestry cases, 5,951 European ancestry controls	NA	8q24.21	8	128933908	intergenic	CCDC26			ENSG00000229140	NA	NA	rs987525-?	rs987525	0	987525	intron_variant	0	0.22	9e-08	7.04575749056067		2.09	[1.59-2.76]	Illumina [495858]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6q24.3	6	148226666	intergenic	AL359382.2 - AL513164.1	ENSG00000287473	ENSG00000224658		69582	10919	rs9497975-?	rs9497975	0	9497975	regulatory_region_variant	1	NR	7e-08	7.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	31125810	CDSN	PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1			ENSG00000231094, ENSG00000233439, ENSG00000206458, ENSG00000233734, ENSG00000204540, ENSG00000235487	NA	NA	rs3815087-?	rs3815087	0	3815087	5_prime_UTR_variant	0	NR	8e-08	7.09691001300806	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	Xq26.2	X	133003128	intergenic	HS6ST2 - USP26	ENSG00000171004	ENSG00000134588		41733	21503	rs17324272-?	rs17324272	0	17324272	intergenic_variant	1	NR	2e-07	6.69897000433602	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	3p23	3	31404088	intergenic	AC115283.1 - THRAP3P1	ENSG00000230111	ENSG00000227339		134682	48744	rs17027625-?	rs17027625	0	17027625	intergenic_variant	1	NR	4e-06	5.39794000867204	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p22.1	6	30057726	ZNRD1, C6orf12	ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP			ENSG00000204623, ENSG00000236598, ENSG00000235394, ENSG00000196299, ENSG00000225618, ENSG00000235814, ENSG00000229653, ENSG00000232691	NA	NA	rs259919-?	rs259919	0	259919	intron_variant	0	NR	3e-07	6.52287874528034	(setpoint)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	32059031	TNXB	TNXB, TNXB, TNXB, TNXB, TNXB, TNXB			ENSG00000168477, ENSG00000206258, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000236221	NA	NA	rs12198173-?	rs12198173	0	12198173	intron_variant	0	NR	3e-06	5.52287874528034	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	1p32.2	1	57339878	NR	DAB1			ENSG00000173406	NA	NA	rs10159302-?	rs10159302	0	10159302	intron_variant	0	NR	9e-06	5.04575749056067	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	1q21.1	1	147037378	NR	NBPF13P			ENSG00000227242	NA	NA	rs12122100-?	rs12122100	0	12122100	intron_variant	0	NR	1e-06	6	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	31306603	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs9264942-?	rs9264942	0	9264942	intron_variant	0	NR	6e-12	11.2218487496164	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	4q32.1	4	160585745	intergenic	LINC02477			ENSG00000249425	NA	NA	rs17291045-?	rs17291045	0	17291045	intron_variant	0	NR	5e-08	7.30102999566398	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	5q32	5	150027170	NR	HMGXB3			ENSG00000113716	NA	NA	rs2304069-?	rs2304069	0	2304069	intron_variant	0	NR	7e-06	5.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	21q22.12	21	35161365	NR	RUNX1			ENSG00000159216	NA	NA	rs2834812-?	rs2834812	0	2834812	intron_variant	0	NR	9e-06	5.04575749056067	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	9q21.13	9	73543766	intergenic	AL451127.2			ENSG00000286840	NA	NA	rs11143609-?	rs11143609	0	11143609	intron_variant	0	NR	7e-06	5.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	11q14.3	11	90853732	intergenic	DISC1FP1			ENSG00000261645	NA	NA	rs12274302-?	rs12274302	0	12274302	non_coding_transcript_exon_variant	0	NR	4e-07	6.39794000867204	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	2q37.1	2	233593475	intergenic	UGT1A12P - UGT1A11P	ENSG00000228949	ENSG00000227846		7184	10078	rs13394720-?	rs13394720	0	13394720	intergenic_variant	1	NR	5e-07	6.30102999566398	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	16q23.1	16	74847922	intergenic	AC009132.1 - WDR59	ENSG00000261458	ENSG00000103091		4039	23440	rs16948255-?	rs16948255	0	16948255	intergenic_variant	1	NR	1e-06	6	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	2p16.1	2	56136242	intergenic	AC011306.1			ENSG00000272180	NA	NA	rs6751715-?	rs6751715	0	6751715	intron_variant	0	NR	1e-06	6	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	10q11.23	10	49353462	intergenic	C10orf71 - DRGX	ENSG00000177354	ENSG00000165606		25970	10719	rs4838508-?	rs4838508	0	4838508	intergenic_variant	1	NR	2e-06	5.69897000433602	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6q27	6	169558886	NR	WDR27, AL031315.1			ENSG00000184465, ENSG00000285733	NA	NA	rs3734905-?	rs3734905	0	3734905	non_coding_transcript_exon_variant	0	NR	2e-06	5.69897000433602	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	2q32.3	2	192469177	intergenic	TMEFF2 - AC062039.1	ENSG00000144339	ENSG00000229395		274244	160742	rs1385351-?	rs1385351	0	1385351	intergenic_variant	1	NR	4e-06	5.39794000867204	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.32	6	32408694	NOTCH4, BTNL2	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794		931	31184	rs3763313-?	rs3763313	0	3763313	intergenic_variant	1	NR	2e-06	5.69897000433602	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	10q26.2	10	128338841	intergenic	AL390763.1 - LINC02667	ENSG00000234640	ENSG00000224190		18627	573969	rs11818629-?	rs11818629	0	11818629	intergenic_variant	1	NR	3e-06	5.52287874528034	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	31464003	HCP5, HLA-B	HCP5			ENSG00000206337	NA	NA	rs2395029-?	rs2395029	0	2395029	non_coding_transcript_exon_variant	0	NR	1e-11	11	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p22.1	6	30002812	HLA-A, ZNRD1, RNF39	ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP			ENSG00000204623, ENSG00000236598, ENSG00000235394, ENSG00000196299, ENSG00000225618, ENSG00000235814, ENSG00000229653, ENSG00000232691	NA	NA	rs7758512-?	rs7758512	0	7758512	intron_variant	0	NR	2e-08	7.69897000433602	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	31834764	SNORD52	SNHG32, SNHG32, SNHG32, SNHG32, AL671762.1			ENSG00000226710, ENSG00000234728, ENSG00000204387, ENSG00000229300, ENSG00000285565	NA	NA	rs9368699-?	rs9368699	0	9368699	5_prime_UTR_variant	0	NR	5e-08	7.30102999566398	(progression)	NA		Illumina [NR]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	5q31.1	5	132660151	IL13	TH2LCRR, IL13			ENSG00000223442, ENSG00000169194	NA	NA	rs1295686-T	rs1295686	0	1295686	intron_variant	0	0.20	1e-07	7		1.15	[1.09-1.20]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	2q12.1	2	102369762	IL18R1	IL18R1			ENSG00000115604	NA	NA	rs3771166-G	rs3771166	0	3771166	intron_variant	0	0.62	3e-09	8.52287874528034		1.15	[1.10-1.20]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	9p24.1	9	6190076	IL33	AL162384.1 - GTF3AP1	ENSG00000228739	ENSG00000237274		123362	5858	rs1342326-C	rs1342326	0	1342326	intergenic_variant	1	0.16	9e-10	9.04575749056067		1.2	[1.13-1.28]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	17q21.1	17	39965740	GSDMA	GSDMA			ENSG00000167914	NA	NA	rs3894194-A	rs3894194	0	3894194	missense_variant	0	0.45	5e-09	8.30102999566398		1.17	[1.11-1.23]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	22q12.3	22	37137994	IL2RB	IL2RB			ENSG00000100385	NA	NA	rs2284033-G	rs2284033	0	2284033	intron_variant	0	0.56	1e-08	8		1.12	[1.08-1.16]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	15q22.33	15	67154447	SMAD3	SMAD3			ENSG00000166949	NA	NA	rs744910-G	rs744910	0	744910	intron_variant	0	0.49	4e-09	8.39794000867204		1.12	[1.09-1.16]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	6p21.32	6	32658092	HLA-DQ	HLA-DQA1 - HLA-DQB1	ENSG00000196735	ENSG00000231286		11030	1375	rs9273349-C	rs9273349	0	9273349	TF_binding_site_variant	1	0.58	7e-14	13.1549019599857		1.18	[1.13-1.24]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	17q21.1	17	39905943	GSDMB	GSDMB			ENSG00000073605	NA	NA	rs2305480-G	rs2305480	0	2305480	missense_variant	0	0.55	1e-07	7		1.18	[1.11-1.23]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	5q31.1	5	132387596	SLC22A5	SLC22A5			ENSG00000197375	NA	NA	rs2073643-T	rs2073643	0	2073643	intron_variant	0	0.45	2e-07	6.69897000433602		1.11	[1.06-1.15]	Illumina [582892]	N
2010-10-14	20860503	Moffatt MF	2010-09-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20860503	A large-scale, consortium-based genomewide association study of asthma.	Asthma	10,365 cases, 16,110 controls	NA	15q22.2	15	60777789	RORA	RORA			ENSG00000069667	NA	NA	rs11071559-C	rs11071559	0	11071559	intron_variant	0	0.86	1e-07	7		1.18	[1.11-1.25]	Illumina [582892]	N
2009-09-04	19684604	Papaemmanuil E	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684604	Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	907 European ancestry cases, 2,398 European ancestry controls	NA	7p12.2	7	50402906	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs4132601-C	rs4132601	0	4132601	3_prime_UTR_variant	0	0.28	1e-19	19		1.69	[1.58-1.81]	Illumina [291473]	N
2009-09-04	19684604	Papaemmanuil E	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684604	Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	907 European ancestry cases, 2,398 European ancestry controls	NA	14q11.2	14	23119848	CEBPE	CEBPE - SLC7A8	ENSG00000092067	ENSG00000092068		232	5447	rs2239633-G	rs2239633	0	2239633	regulatory_region_variant	1	0.52	3e-07	6.52287874528034		1.34	[1.22-1.45]	Illumina [291473]	N
2009-09-04	19684604	Papaemmanuil E	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684604	Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	907 European ancestry cases, 2,398 European ancestry controls	NA	10q21.2	10	61992400	ARID5B	ARID5B			ENSG00000150347	NA	NA	rs7089424-C	rs7089424	0	7089424	intron_variant	0	0.34	7e-19	18.1549019599857		1.65	[1.54-1.76]	Illumina [291473]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	7p21.1	7	20007952	intergenic	AC005062.1			ENSG00000243004	NA	NA	rs38152-?	rs38152	0	38152	intron_variant	0	NR	7e-08	7.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	14q23.1	14	57888330	intergenic	SLC35F4			ENSG00000151812	NA	NA	rs8013190-?	rs8013190	0	8013190	intron_variant	0	NR	7e-08	7.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p12.1	6	55283305	HCRTR2	HCRTR2 - GFRAL	ENSG00000137252	ENSG00000187871		685	44164	rs9367630-?	rs9367630	0	9367630	intergenic_variant	1	NR	1e-07	7	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	11q14.2	11	88588556	intergenic	GRM5			ENSG00000168959	NA	NA	rs16914280-?	rs16914280	0	16914280	intron_variant	0	NR	3e-07	6.52287874528034	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	13q13.3	13	35603682	intergenic	NBEA			ENSG00000172915	NA	NA	rs1777672-?	rs1777672	0	1777672	intron_variant	0	NR	4e-07	6.39794000867204	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	Xq21.31	X	87935349	intergenic	AL136363.2 - AL035246.1	ENSG00000271056	ENSG00000230706		125466	126241	rs12012519-?	rs12012519	0	12012519	intergenic_variant	1	NR	7e-06	5.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	18q21.31	18	57316323	intergenic	RNU6-737P - ST8SIA3	ENSG00000202240	ENSG00000177511		31615	36234	rs1120787-?	rs1120787	0	1120787	intergenic_variant	1	NR	7e-06	5.15490195998574	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	2q22.3	2	146614456	intergenic	PABPC1P2 - AC103881.1	ENSG00000198526	ENSG00000271583		25146	219045	rs10928302-?	rs10928302	0	10928302	intergenic_variant	1	NR	8e-06	5.09691001300806	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	16p13.2	16	10089230	NR	GRIN2A			ENSG00000183454	NA	NA	rs1463132-?	rs1463132	0	1463132	intron_variant	0	NR	8e-06	5.09691001300806	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	30880476	VARS2, DDR1, DPCR1	DDR1, DDR1, DDR1, DDR1, DDR1, DDR1			ENSG00000215522, ENSG00000230456, ENSG00000137332, ENSG00000234078, ENSG00000204580, ENSG00000223680	NA	NA	rs7756521-?	rs7756521	0	7756521	intron_variant	0	NR	1e-06	6	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p22.1	6	30152113	TRIM10	TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10, TRIM10			ENSG00000204613, ENSG00000137394, ENSG00000229381, ENSG00000237703, ENSG00000237192, ENSG00000227472, ENSG00000229346	NA	NA	rs9468692-?	rs9468692	0	9468692	3_prime_UTR_variant	0	NR	1e-06	6	(setpoint)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	31306603	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs9264942-C	rs9264942	0	9264942	intron_variant	0	0.412	6e-32	31.2218487496164	(setpoint)	5.3	[NR] % increase	Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	2p25.2	2	5994808	NR	SILC1			ENSG00000232044	NA	NA	rs1405262-?	rs1405262	0	1405262	non_coding_transcript_exon_variant	0	NR	6e-06	5.22184874961636	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	1q42.3	1	234849241	intergenic	AL391832.4			ENSG00000286263	NA	NA	rs2069084-?	rs2069084	0	2069084	intron_variant	0	NR	6e-06	5.22184874961636	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	5q23.2	5	125407574	intergenic	LINC02240, AC116362.1			ENSG00000260192, ENSG00000248752	NA	NA	rs2637496-?	rs2637496	0	2637496	intron_variant	0	NR	9e-06	5.04575749056067	(progression)	NA		Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	6p21.33	6	31464003	HCP5, HLA-B	HCP5			ENSG00000206337	NA	NA	rs2395029-G	rs2395029	0	2395029	non_coding_transcript_exon_variant	0	0.048	5e-35	34.301029995664	(setpoint)	5.8	[NR] % increase	Illumina [NR]	N
2010-01-19	20041166	Fellay J	2009-12-24	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20041166	Common genetic variation and the control of HIV-1 in humans.	HIV-1 control	2,362 European ancestry cases	NA	8q13.3	8	69812519	NR	SLCO5A1			ENSG00000137571	NA	NA	rs16936455-?	rs16936455	0	16936455	intron_variant	0	NR	7e-06	5.15490195998574	(progression)	NA		Illumina [NR]	N
2011-05-26	21493818	Shaw SY	2011-04-21	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/21493818	Genetic and clinical correlates of early-outgrowth colony-forming units.	Monocyte early outgrowth colony forming units	1,654 European ancestry individuals	NA	6q25.3	6	160368264	SLC22A, LPAL2, LPA	SLC22A3			ENSG00000146477	NA	NA	rs402219-G	rs402219	0	402219	intron_variant	0	0.3	6e-07	6.22184874961636		0.19	[0.11-0.27] unit increase	Affymetrix [~ 2500000] (imputed)	N
2011-05-26	21493818	Shaw SY	2011-04-21	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/21493818	Genetic and clinical correlates of early-outgrowth colony-forming units.	Monocyte early outgrowth colony forming units	1,654 European ancestry individuals	NA	1q41	1	220803991	MOSC1	AL445423.3, MARC1			ENSG00000286231, ENSG00000186205	NA	NA	rs6693017-G	rs6693017	0	6693017	intron_variant	0	0.15	3e-07	6.52287874528034		0.24	[0.14-0.34] unit increase	Affymetrix [~ 2500000] (imputed)	N
2011-05-26	21493818	Shaw SY	2011-04-21	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/21493818	Genetic and clinical correlates of early-outgrowth colony-forming units.	Monocyte early outgrowth colony forming units	1,654 European ancestry individuals	NA	2p16.1	2	60054473	BCL11A	AC007100.1			ENSG00000271955	NA	NA	rs6712720-C	rs6712720	0	6712720	intron_variant	0	0.49	4e-06	5.39794000867204		0.16	[0.08-0.24] unit increase	Affymetrix [~ 2500000] (imputed)	N
2009-07-01	19561606	Thorleifsson G	2009-06-28	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19561606	Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density.	Kidney stones	1,507 European ancestry cases, 34,033 European ancestry controls	2,266 European ancestry cases, 8,477 European ancestry controls	21q22.13	21	36461009	CLDN14	AP000695.2, CLDN14, AP000695.1			ENSG00000233818, ENSG00000159261, ENSG00000230479	NA	NA	rs219780-C	rs219780	0	219780	synonymous_variant	0	0.79	4e-12	11.397940008672		1.25	[1.17-1.33]	Illumina [303120]	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	2q32.1	2	187468337	TFPI	AC007319.1, TFPI			ENSG00000224063, ENSG00000003436	NA	NA	rs4140885-A	rs4140885	0	4140885	intron_variant	0	0.317	5e-08	7.30102999566398		0.217	[0.12-0.31] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	7q21.3	7	93920284	GNG11	AC002076.2 - GNG11	ENSG00000278388	ENSG00000127920		5176	1451	rs180242-T	rs180242	0	180242	intergenic_variant	1	0.333	7e-12	11.1549019599857		0.316	[0.21-0.42] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	14q31.3	14	85343567	FLRT2	AL357172.1 - AL049775.2	ENSG00000259044	ENSG00000258902		104093	18890	rs17796783-T	rs17796783	0	17796783	intergenic_variant	1	0.716	3e-13	12.5228787452803		0.334	[0.24-0.43] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	12p11.1	12	33424055	SYT10	SYT10			ENSG00000110975	NA	NA	rs7980799-A	rs7980799	0	7980799	intron_variant	0	0.401	6e-24	23.2218487496164		0.377	[0.29-0.47] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	12p12.1	12	24617944	LINC00477, C12orf67	KNOP1P1 - AC087312.1	ENSG00000256852	ENSG00000244662		33395	24743	rs17287293-A	rs17287293	0	17287293	intergenic_variant	1	0.85	3e-20	19.5228787452803		0.444	[0.32-0.57] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	1q32.2	1	207767508	CD46	CD46			ENSG00000117335	NA	NA	rs11118555-A	rs11118555	0	11118555	non_coding_transcript_exon_variant	0	0.124	4e-26	25.397940008672		0.612	[0.48-0.75] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	14q11.2	14	23392602	MYH6	MYH6			ENSG00000197616	NA	NA	rs365990-G	rs365990	0	365990	missense_variant	0	0.353	5e-45	44.301029995664		0.564	[0.47-0.66] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	6q22.31	6	121810339	GJA1	AL603865.1 - HMGB3P18	ENSG00000217139	ENSG00000220184		126067	47840	rs1015451-C	rs1015451	0	1015451	intergenic_variant	1	0.102	1e-33	33		0.713	[0.57-0.85] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	7q22.1	7	100899511	ACHE	ACHE - RN7SL549P	ENSG00000087085	ENSG00000239825		2537	6780	rs13245899-G	rs13245899	0	13245899	intergenic_variant	1	0.195	8e-27	26.0969100130081		0.447	[0.34-0.55] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	11q12.2	11	61803910	FADS1	FADS2, FADS1			ENSG00000134824, ENSG00000149485	NA	NA	rs174549-A	rs174549	0	174549	5_prime_UTR_variant	0	0.31	1e-22	22		0.358	[0.27-0.45] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	6q22.31	6	118346359	SLC35F1	SLC35F1 - AL589993.1	ENSG00000196376	ENSG00000216809		28683	106110	rs11153730-T	rs11153730	0	11153730	intergenic_variant	1	0.509	8e-21	20.0969100130081		0.381	[0.29-0.47] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	20q11.23	20	38215636	KIAA1755	KIAA1755			ENSG00000149633	NA	NA	rs6127471-C	rs6127471	0	6127471	intron_variant	0	0.54	5e-29	28.301029995664		0.429	[0.34-0.52] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	2q31.2	2	178856319	CCDC141	CCDC141, AC092640.1			ENSG00000163492, ENSG00000287149	NA	NA	rs17362588-A	rs17362588	0	17362588	missense_variant	0	0.114	4e-26	25.397940008672		0.736	[0.59-0.89] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	15q24.1	15	73373165	HCN4	HCN4 - REC114	ENSG00000138622	ENSG00000183324		4207	69999	rs4489968-T	rs4489968	0	4489968	intergenic_variant	1	0.843	4e-20	19.397940008672		0.513	[0.40-0.63] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	3q26.33	3	179455191	GNB4	AC007620.1 - MTHFD2P7	ENSG00000239255	ENSG00000181260		2772	9155	rs7612445-G	rs7612445	0	7612445	regulatory_region_variant	1	0.816	2e-14	13.698970004336		0.358	[0.24-0.48] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	7q33	7	136957887	CHRM2	CHRM2, AC009264.1			ENSG00000181072, ENSG00000234352	NA	NA	rs2350782-C	rs2350782	0	2350782	intron_variant	0	0.116	1e-12	12		0.505	[0.35-0.66] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	5q35.1	5	173237160	NKX2-5	NKX2-5 - Y_RNA	ENSG00000183072	ENSG00000265852		1849	17030	rs6882776-G	rs6882776	0	6882776	regulatory_region_variant	1	0.68	2e-12	11.698970004336		0.301	[0.20-0.40] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	2q37.1	2	231406573	B3GNT7	B3GNT7 - ZBTB8OSP2	ENSG00000156966	ENSG00000172799		5409	27350	rs13030174-A	rs13030174	0	13030174	regulatory_region_variant	1	0.733	1e-10	10		0.3	[0.20-0.40] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	3q26.31	3	172067378	FNDC3B	FNDC3B			ENSG00000075420	NA	NA	rs9647379-C	rs9647379	0	9647379	intron_variant	0	0.4	1e-09	9		0.206	[0.11-0.30] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	12q23.3	12	106755644	RFX4	AC079385.1, RFX4			ENSG00000257545, ENSG00000111783	NA	NA	rs2067615-A	rs2067615	0	2067615	intron_variant	0	0.49	2e-09	8.69897000433602		0.278	[0.19-0.36] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	12q12	12	38712929	CPNE8	CPNE8			ENSG00000139117	NA	NA	rs826838-C	rs826838	0	826838	intron_variant	0	0.443	4e-09	8.39794000867204		0.234	[0.15-0.32] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	16p13.3	16	6846127	A2BP1	RBFOX1			ENSG00000078328	NA	NA	rs11645781-G	rs11645781	0	11645781	intron_variant	0	0.696	2e-07	6.69897000433602		NA		Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	12q24.11	12	110717726	PPP1CC	HVCN1 - PPP1CC	ENSG00000122986	ENSG00000186298		12776	1954	rs11065706-T	rs11065706	0	11065706	intergenic_variant	1	0.756	6e-07	6.22184874961636		NA		Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	6p21.2	6	36824281	CPNE5	CPNE5			ENSG00000124772	NA	NA	rs236373-C	rs236373	0	236373	intron_variant	0	0.727	9e-07	6.04575749056067		NA		Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	4q31.22	4	146578186	SLC10A7	SLC10A7 - RNU1-44P	ENSG00000120519	ENSG00000207182		56222	1862	rs10213084-G	rs10213084	0	10213084	intergenic_variant	1	0.869	4e-06	5.39794000867204		NA		Affymetrix, Illumina [2516789] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	1q24.3	1	172377408	PIGC, DNM3	PIGC, DNM3			ENSG00000135845, ENSG00000197959	NA	NA	rs1011731-G	rs1011731	0	1011731	intron_variant	0	0.43	1e-17	17		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	6p21.1	6	43791136	VEGFA	VEGFA - AL157371.2	ENSG00000112715	ENSG00000283573		4649	12057	rs6905288-A	rs6905288	0	6905288	intergenic_variant	1	0.56	6e-25	24.2218487496164		0.04	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	1p12	1	118961220	TBX15, WARS2	TBX15			ENSG00000092607	NA	NA	rs984222-G	rs984222	0	984222	intron_variant	0	0.64	9e-25	24.0457574905607		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	1q41	1	219577375	LYPLAL1	AL356364.1 - ZC3H11B	ENSG00000238232	ENSG00000215817		19674	30635	rs4846567-G	rs4846567	0	4846567	regulatory_region_variant	1	0.71	7e-21	20.1549019599857		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	12p11.23	12	26300350	ITPR2, SSPN	AC022509.2, AC022509.1			ENSG00000256234, ENSG00000255750	NA	NA	rs718314-G	rs718314	0	718314	intron_variant	0	0.26	1e-17	17		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	7p15.2	7	25831489	NFE2L3	AC018706.1			ENSG00000286725	NA	NA	rs1055144-T	rs1055144	0	1055144	non_coding_transcript_exon_variant	0	0.21	1e-24	24		0.04	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	12q13.13	12	53948900	HOXC13	HOXC13 - HOXC12	ENSG00000123364	ENSG00000123407		2356	6003	rs1443512-A	rs1443512	0	1443512	regulatory_region_variant	1	0.24	6e-17	16.2218487496164		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	3p14.1	3	64719689	ADAMTS9	ADAMTS9-AS2			ENSG00000241684	NA	NA	rs6795735-C	rs6795735	0	6795735	intron_variant	0	0.59	1e-13	13		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	3p21.1	3	52472410	NISCH, STAB1	NISCH			ENSG00000010322	NA	NA	rs6784615-T	rs6784615	0	6784615	intron_variant	0	0.94	4e-10	9.39794000867204		0.04	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	6p21.32	6	32396178	BTNL2	TSBP1-AS1, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2, BTNL2			ENSG00000225914, ENSG00000226127, ENSG00000225412, ENSG00000204290, ENSG00000225845, ENSG00000229741, ENSG00000224770, ENSG00000229597, ENSG00000224242	NA	NA	rs2076529-C	rs2076529	0	2076529	synonymous_variant	0	0.43	4e-07	6.39794000867204		0.02	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	10p11.22	10	31701695	ZEB1	MACORIS			ENSG00000237797	NA	NA	rs7081678-A	rs7081678	0	7081678	intron_variant	0	0.09	6e-06	5.22184874961636		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	6q22.33	6	127131494	RSPO3	AL356534.1, RSPO3			ENSG00000286215, ENSG00000146374	NA	NA	rs9491696-G	rs9491696	0	9491696	intron_variant	0	0.48	2e-40	39.698970004336		0.04	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	2q24.3	2	164656581	GRB14	COBLL1			ENSG00000082438	NA	NA	rs10195252-T	rs10195252	0	10195252	intron_variant	0	0.60	2e-24	23.698970004336		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	6p25.1	6	6742916	LY86	AL031123.1 - AL136361.1	ENSG00000226281	ENSG00000224532		3886	15360	rs1294421-G	rs1294421	0	1294421	regulatory_region_variant	1	0.61	2e-17	16.698970004336		0.03	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	22q12.1	22	29055683	ZNRF3, KREMEN1	ZNRF3			ENSG00000183579	NA	NA	rs4823006-A	rs4823006	0	4823006	3_prime_UTR_variant	0	0.57	1e-11	11		0.02	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2010-11-17	20935629	Heid IM	2010-10-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Waist-hip ratio	Up to 77,167 European ancestry individuals	Up to 113,636 European ancestry individuals	5q35.2	5	173935455	CPEB4	CPEB4			ENSG00000113742	NA	NA	rs6861681-A	rs6861681	0	6861681	intron_variant	0	0.34	2e-09	8.69897000433602		0.02	[NR] unit increase	Affymetrix, Illumina, Perlegen [up to 2850269] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	3p21.1	3	53344218	DCP1A	CACNA1D, DCP1A			ENSG00000157388, ENSG00000272886	NA	NA	rs2029213-C	rs2029213	0	2029213	intron_variant	0	0.639	7e-06	5.15490195998574		NA		Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	6q22.31	6	121460244	GJA1	RNU4-35P - AL138729.1	ENSG00000199458	ENSG00000219784		6123	18029	rs11154027-C	rs11154027	0	11154027	intergenic_variant	1	0.567	7e-12	11.1549019599857	(Conditional on rs1015451, rs17083533)	0.32	[0.22-0.42] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	1q32.2	1	207955720	CD34	AL356275.1 - LINC02767	ENSG00000285719	ENSG00000284237		38632	3572	rs11578508-A	rs11578508	0	11578508	intergenic_variant	1	0.665	4e-10	9.39794000867204	(Conditonal on rs11118555)	0.51	[0.39-0.63] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	6q22.31	6	121409576	GJA1	AL139098.2 - GJA1	ENSG00000272714	ENSG00000152661		19219	26019	rs17083533-A	rs17083533	0	17083533	intergenic_variant	1	0.077	1e-08	8	(Conditional on rs1015451, rs11154027)	0.74	[0.49-0.99] unit increase	Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	19q13.2	19	38697472	ACTN4	ACTN4, ACTN4			ENSG00000130402, ENSG00000282844	NA	NA	rs11083475-G	rs11083475	0	11083475	intron_variant	0	0.537	2e-06	5.69897000433602		NA		Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	2q31.2	2	177815704	PDE11A	PDE11A, PDE11A			ENSG00000284741, ENSG00000128655	NA	NA	rs13413635-G	rs13413635	0	13413635	intron_variant	0	0.033	3e-07	6.52287874528034		NA		Affymetrix, Illumina [2516789] (imputed)	N
2013-08-20	23583979	den Hoed M	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Heart rate	85,787 European ancestry individuals, 6,568 Indian Asian ancestry indiviudals	88,823 European ancestry individuals	5q31.2	5	137859073	MYOT	AC106791.1			ENSG00000250159	NA	NA	rs7722600-A	rs7722600	0	7722600	non_coding_transcript_exon_variant	0	0.815	3e-07	6.52287874528034		NA		Affymetrix, Illumina [2516789] (imputed)	N
2012-02-25	22286170	Cusanovich DA	2012-01-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22286170	The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.	Lymphocyte counts	462 Hutterite individuals	NA	1p32.2	1	56661246	PRKAA2	PRKAA2			ENSG00000162409	NA	NA	rs2746347-?	rs2746347	0	2746347	intron_variant	0	NR	4e-07	6.39794000867204		NA		Affymetrix [279749]	N
2012-02-25	22286170	Cusanovich DA	2012-01-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22286170	The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.	Lymphocyte counts	462 Hutterite individuals	NA	21q22.3	21	46599955	S100B	S100B			ENSG00000160307	NA	NA	rs881827-?	rs881827	0	881827	intron_variant	0	NR	9e-06	5.04575749056067		NA		Affymetrix [279749]	N
2009-07-10	19571809	Shi J	2009-07-01	Nature	www.ncbi.nlm.nih.gov/pubmed/19571809	Common variants on chromosome 6p22.1 are associated with schizophrenia.	Schizophrenia	2,681 European ancestry cases, 2,653 European ancestry controls, 1,286 African American cases, 973 African American controls	5,327 European ancestry cases, 16,424 European ancestry controls	6p22.1	6	27176104	HIST1H2BJ, SLC17A1, BTN3A2, BTN2A2, BTN3A1, HIST1H2AG, POM121L2, ZNF184, PRSS16, SLC17A3	MIR3143 - RPL10P2	ENSG00000265565	ENSG00000174572		28416	35140	rs13194053-T	rs13194053	0	13194053	intergenic_variant	1	0.82	1e-08	8	(EA)	1.28	[NR]	Affymetrix [up to 843798]	N
2009-07-10	19571809	Shi J	2009-07-01	Nature	www.ncbi.nlm.nih.gov/pubmed/19571809	Common variants on chromosome 6p22.1 are associated with schizophrenia.	Schizophrenia	2,681 European ancestry cases, 2,653 European ancestry controls, 1,286 African American cases, 973 African American controls	5,327 European ancestry cases, 16,424 European ancestry controls	6p21.32	6	32634492	HLA-DQA1	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs9272219-G	rs9272219	0	9272219	intron_variant	0	0.72	7e-08	7.15490195998574	(EA)	1.14	[NR]	Affymetrix [up to 843798]	N
2010-01-13	20018283	Heid IM	2009-12-02	Atherosclerosis	www.ncbi.nlm.nih.gov/pubmed/20018283	Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.	Adiponectin levels	4,659 European ancestry individuals	13,795 European ancestry individuals	3q27.3	3	186852664	ADIPOQ	ADIPOQ, ADIPOQ-AS1			ENSG00000181092, ENSG00000226482	NA	NA	rs17366568-G	rs17366568	0	17366568	non_coding_transcript_exon_variant	0	0.89	1e-41	41		0.13	[NR] log(ug/ml) increase	Affymetrix, Illumina [2585854] (imputed)	N
2009-12-29	20031604	Cheng YC	2009-08-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031604	Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.	Matrix metalloproteinase levels	778 Old Order Amish individuals	NA	11q22.2	11	102820751	MMP-1	WTAPP1			ENSG00000255282	NA	NA	rs11225434-C	rs11225434	0	11225434	intron_variant	0	0.38	9e-29	28.0457574905607		0.39	[NR] unit increase	Affymetrix [338079]	N
2009-12-29	20031604	Cheng YC	2009-08-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031604	Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.	Matrix metalloproteinase levels	778 Old Order Amish individuals	NA	11q22.3	11	104463511	MMP-3, MMP-1	LINC02552			ENSG00000256422	NA	NA	rs11226373-G	rs11226373	0	11226373	intron_variant	0	0.15	2e-18	17.698970004336		0.44	[NR] unit increase	Affymetrix [338079]	N
2009-12-29	20031604	Cheng YC	2009-08-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031604	Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.	Matrix metalloproteinase levels	778 Old Order Amish individuals	NA	20p11.23	20	19590937	SLC24A3	SLC24A3			ENSG00000185052	NA	NA	rs3790268-?	rs3790268	0	3790268	intron_variant	0	NR	3e-07	6.52287874528034		NA		Affymetrix [338079]	N
2009-12-29	20031604	Cheng YC	2009-08-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031604	Genome-wide association scan identifies variants near Matrix Metalloproteinase (MMP) genes on chromosome 11q21-22 strongly associated with serum MMP-1 levels.	Matrix metalloproteinase levels	778 Old Order Amish individuals	NA	11q22.2	11	102824377	MMP	WTAPP1			ENSG00000255282	NA	NA	rs495366-A	rs495366	0	495366	intron_variant	0	0.36	6e-34	33.2218487496164		0.44	[NR] unit decrease	Affymetrix [338079]	N
2009-09-28	19729412	Tonjes A	2009-09-03	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19729412	Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.	Height	929 Sorbian (founder/genetic isolate) individuals	5,758 European ancestry individuals	12q24.33	12	131091646	GPR133	ADGRD1			ENSG00000111452	NA	NA	rs1569019-?	rs1569019	0	1569019	intron_variant	0	NR	5e-08	7.30102999566398		0.95	[0.61-1.29] cm increase	Affymetrix [390619]	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	3q26.32	3	177573909	NR	LINC00578			ENSG00000228221	NA	NA	rs644695-A	rs644695	0	644695	intron_variant	0	0.88	5e-06	5.30102999566398		1.35	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	Xq21.33	X	95824871	NR	AL365400.2 - AL137845.2	ENSG00000270583	ENSG00000232842		103727	148457	rs5990417-T	rs5990417	0	5990417	intergenic_variant	1	0.83	6e-06	5.22184874961636		1.23	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	8p21.3	8	20208538	SLC18A1, ATP6V1B2, LZTS1	ATP6V1B2			ENSG00000147416	NA	NA	rs1106634-A	rs1106634	0	1106634	intron_variant	0	0.14	7e-07	6.15490195998574		1.3	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	7p15.3	7	21464809	SP4	SP4			ENSG00000105866	NA	NA	rs17144465-G	rs17144465	0	17144465	intron_variant	0	0.03	8e-07	6.09691001300806		1.56	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	3p26.1	3	7487868	GRM7	GRM7			ENSG00000196277	NA	NA	rs9870680-T	rs9870680	0	9870680	intron_variant	0	0.44	1e-06	6		1.19	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	6p25.1	6	6612234	LY86	LY86-AS1, LY86			ENSG00000216863, ENSG00000112799	NA	NA	rs2326810-G	rs2326810	0	2326810	intron_variant	0	0.92	7e-06	5.15490195998574		1.41	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	10p12.1	10	29002969	NR	LINC01517 - LYZL1	ENSG00000232624	ENSG00000120563		61059	286092	rs1612122-T	rs1612122	0	1612122	intergenic_variant	1	0.48	7e-06	5.15490195998574		1.17	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	7q32.3	7	131215362	AK294384	MKLN1			ENSG00000128585	NA	NA	rs10265216-A	rs10265216	0	10265216	intron_variant	0	0.28	3e-06	5.52287874528034		1.19	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-01-19	20038947	Shyn SI	2009-12-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20038947	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	Major depressive disorder (broad)	3,957 European ancestry cases, 3,428 European ancestry controls	NA	2p14	2	67715348	BC043421	AC007422.1 - LINC01812	ENSG00000235495	ENSG00000237013		31271	80706	rs724568-C	rs724568	0	724568	intergenic_variant	1	0.36	5e-06	5.30102999566398		1.17	[NR]	Affymetrix, Perlegen [2391203] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	11p15.5	11	2529500	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs179429-A	rs179429	0	179429	intron_variant	0	0.167	7e-06	5.15490195998574	(ADP)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	12q13.3	12	56810376	HSD17B6	HSD17B6 - AC121758.2	ENSG00000025423	ENSG00000258679		22586	12609	rs12367822-T	rs12367822	0	12367822	intergenic_variant	1	0.277	1e-06	6	(collagen)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	1q23.1	1	156899255	PEAR1	PEAR1			ENSG00000187800	NA	NA	rs12566888-A	rs12566888	0	12566888	intron_variant	0	0.102	4e-16	15.397940008672	(ADP)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	11p15.4	11	10647681	MRVI1	MRVI1			ENSG00000072952	NA	NA	rs7940646-T	rs7940646	0	7940646	intron_variant	0	0.381	1e-06	6	(ADP)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	1q23.1	1	156899255	PEAR1	PEAR1			ENSG00000187800	NA	NA	rs12566888-A	rs12566888	0	12566888	intron_variant	0	0.103	5e-19	18.301029995664	(epinephrine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	20p13	20	4631231	PRNP	RPS4XP2			ENSG00000226948	NA	NA	rs6052699-A	rs6052699	0	6052699	intron_variant	0	0.507	2e-06	5.69897000433602	(epinephrine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	8p22	8	14531972	SGCZ	SGCZ			ENSG00000185053	NA	NA	rs1903595-G	rs1903595	0	1903595	intron_variant	0	0.303	5e-06	5.30102999566398	(ephinephrine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	10q24.33	10	103498029	NEURL	NEURL1-AS1, NEURL1			ENSG00000235470, ENSG00000107954	NA	NA	rs7071247-T	rs7071247	0	7071247	intron_variant	0	0.119	2e-07	6.69897000433602	(epinephrine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	6p22.1	6	28948475	TRIM27	LINC01556 - KRT18P1	ENSG00000231041	ENSG00000226462		3938	20655	rs4947339-T	rs4947339	0	4947339	regulatory_region_variant	1	0.438	2e-06	5.69897000433602	(epinehprine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	9p24.1	9	8196511	PTPRD	AL135923.2 - PTPRD	ENSG00000231902	ENSG00000153707		235287	117735	rs7044355-G	rs7044355	0	7044355	intergenic_variant	1	0.501	1e-07	7	(collagen)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	10q25.2	10	111149347	ADRA2A	AL355863.1 - BTBD7P2	ENSG00000213247	ENSG00000237618		44099	173431	rs869244-A	rs869244	0	869244	intergenic_variant	1	0.353	3e-12	11.5228787452803	(epinephrine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	19q13.42	19	55014977	GP6	GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, GP6, AC011476.3			ENSG00000275633, ENSG00000278316, ENSG00000275931, ENSG00000277439, ENSG00000278670, ENSG00000274050, ENSG00000276065, ENSG00000276211, ENSG00000274566, ENSG00000088053, ENSG00000267265	NA	NA	rs1671152-T	rs1671152	0	1671152	missense_variant	0	0.142	8e-14	13.0969100130081	(collagen)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	7q36.3	7	155969463	SHH	AC021218.1 - Y_RNA	ENSG00000204876	ENSG00000265852		3120	216659	rs6943029-A	rs6943029	0	6943029	intergenic_variant	1	0.067	8e-08	7.09691001300806	(ADP)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	10q21.3	10	63501424	JMJD1C	JMJD1C			ENSG00000171988	NA	NA	rs2893923-T	rs2893923	0	2893923	intron_variant	0	0.336	5e-08	7.30102999566398	(epinephrine)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-06-22	20526338	Johnson AD	2010-06-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20526338	Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.	Platelet aggregation	Up to 3,991 European ancestry individuals	Up to 840 African American individuals	10p13	10	13061285	MST151	CCDC3			ENSG00000151468	NA	NA	rs525455-G	rs525455	0	525455	intron_variant	0	0.459	7e-07	6.15490195998574	(ADP)	NA		Affymetrix, Illumina [~ 2330000] (imputed)	N
2010-01-13	20032318	Sleiman PM	2009-12-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20032318	Variants of DENND1B associated with asthma in children.	Asthma	793 European ancestry cases, 1,988 European ancestry controls	917 European ancestry cases, 1,546 European ancestry controls, 1,667 African American cases, 2,045 African American controls	1q31.3	1	197356778	CRB1, DENND1B	CRB1			ENSG00000134376	NA	NA	rs2786098-?	rs2786098	0	2786098	intron_variant	0	NR	2e-13	12.698970004336		NA	[NR]	Illumina [~ 550000]	N
2010-01-13	20032318	Sleiman PM	2009-12-23	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/20032318	Variants of DENND1B associated with asthma in children.	Asthma	793 European ancestry cases, 1,988 European ancestry controls	917 European ancestry cases, 1,546 European ancestry controls, 1,667 African American cases, 2,045 African American controls	1q31.3	1	197356778	DENND1B, CRB1	CRB1			ENSG00000134376	NA	NA	rs2786098-?	rs2786098	0	2786098	intron_variant	0	0.848	9e-11	10.0457574905607	(EA)	1.43		Illumina [~ 550000]	N
2010-09-07	20634892	Calboli FC	2010-07-09	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20634892	A genome-wide association study of neuroticism in a population-based sample.	Neuroticism (age interaction)	2,235 European ancestry individuals	NA	13q31.3	13	93358916	GPC6	GPC6			ENSG00000183098	NA	NA	rs9561329-?	rs9561329	0	9561329	intron_variant	0	0.09	1e-07	7		0.17	[0.11-0.23] unit decrease	Affymetrix [1705237] (imputed)	N
2017-08-21	20634892	Calboli FC	2010-07-09	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20634892	A genome-wide association study of neuroticism in a population-based sample.	Neuroticism	2,235 European ancestry individuals	NA	6q22.31	6	124370091	NKAIN2	NKAIN2			ENSG00000188580	NA	NA	rs9491140-?	rs9491140	0	9491140	intron_variant	0	0.33	3e-07	6.52287874528034		0.91	[0.56-1.26] unit decrease	Affymetrix [1705237] (imputed)	N
2017-08-21	20634892	Calboli FC	2010-07-09	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20634892	A genome-wide association study of neuroticism in a population-based sample.	Neuroticism	2,235 European ancestry individuals	NA	15q26.2	15	97975562	ARRDC4	ARRDC4 - AC024651.1	ENSG00000140450	ENSG00000259478		1729	6947	rs4965121-?	rs4965121	0	4965121	intergenic_variant	1	0.38	1e-06	6		0.84	[0.51-1.17] unit decrease	Affymetrix [1705237] (imputed)	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	21q21.1	21	16455971	C21orf34	MIR99AHG			ENSG00000215386	NA	NA	rs2823819-C	rs2823819	0	2823819	intron_variant	0	0.18	7e-07	6.15490195998574		1.65	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	4q22.3	4	94912883	BMPR1B	BMPR1B			ENSG00000138696	NA	NA	rs1859156-?	rs1859156	0	1859156	intron_variant	0	0.79	2e-06	5.69897000433602		1.54	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	6p24.3	6	9030103	LOC389365	HULC			ENSG00000285219	NA	NA	rs438259-?	rs438259	0	438259	intron_variant	0	0.28	4e-06	5.39794000867204		1.49	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	3q24	3	143264057	SLC9A9	PBX2P1 - SLC9A9	ENSG00000244171	ENSG00000181804		86440	1165	rs9810857-T	rs9810857	0	9810857	regulatory_region_variant	1	0.49	6e-06	5.22184874961636		1.41	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	16p13.13	16	10539308	EMP2	EMP2			ENSG00000213853	NA	NA	rs11074889-A	rs11074889	0	11074889	intron_variant	0	0.16	7e-07	6.15490195998574		1.68	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	17q24.1	17	65646424	CCDC46	CEP112			ENSG00000154240	NA	NA	rs8074751-?	rs8074751	0	8074751	intron_variant	0	0.61	1e-06	6		1.45	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	15q14	15	36001404	ATPBD4	AC021351.1, LINC02853			ENSG00000259639, ENSG00000259245	NA	NA	rs4923705-C	rs4923705	0	4923705	intron_variant	0	0.27	2e-06	5.69897000433602		1.51	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	2q37.1	2	233675678	UGT1A9	UGT1A8, UGT1A10, UGT1A9			ENSG00000242366, ENSG00000242515, ENSG00000241119	NA	NA	rs2602381-A	rs2602381	0	2602381	intron_variant	0	0.48	4e-06	5.39794000867204		1.42	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	7q35	7	145144438	LOC643308	RPL7P59 - AC004911.1	ENSG00000225918	ENSG00000226592		103497	125076	rs10487524-T	rs10487524	0	10487524	intergenic_variant	1	0.15	9e-06	5.04575749056067		1.6	[NR]	Illumina [835136]	N
2010-09-07	20732626	Mick E	2010-05-14	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20732626	Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.	Attention deficit hyperactivity disorder	735 trios from 732 families	NA	4q25	4	110105771	ELOVL6	ELOVL6			ENSG00000170522	NA	NA	rs10011926-?	rs10011926	0	10011926	intron_variant	0	0.78	8e-06	5.09691001300806		1.49	[NR]	Illumina [835136]	N
2010-01-13	20031538	Heid IM	2008-10-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031538	Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.	HDL cholesterol	Up to 4,274 European ancestry individuals	Up to 15,873 European ancestry individuals	8p21.3	8	19975135	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		7876	103979	rs17482753-T	rs17482753	0	17482753	regulatory_region_variant	1	0.11	3e-11	10.5228787452803		2.02	[NR] mg/dl increase	Affymetrix [up to 2557253] (imputed)	N
2010-01-13	20031538	Heid IM	2008-10-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031538	Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.	HDL cholesterol	Up to 4,274 European ancestry individuals	Up to 15,873 European ancestry individuals	18q21.1	18	49632720	LIPG	LIPG - SMUG1P1	ENSG00000101670	ENSG00000267444		33535	17630	rs7240405-A	rs7240405	0	7240405	intergenic_variant	1	0.15	5e-10	9.30102999566398		2.27	[NR] mg/dl decrease	Affymetrix [up to 2557253] (imputed)	N
2010-01-13	20031538	Heid IM	2008-10-01	Circ Cardiovasc Genet	www.ncbi.nlm.nih.gov/pubmed/20031538	Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions.	HDL cholesterol	Up to 4,274 European ancestry individuals	Up to 15,873 European ancestry individuals	16q13	16	56951227	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		6363	10696	rs9989419-A	rs9989419	0	9989419	regulatory_region_variant	1	0.38	9e-27	26.0457574905607		2.66	[NR] mg/dl decrease	Affymetrix [up to 2557253] (imputed)	N
2010-03-06	20139977	Codd V	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139977	Common variants near TERC are associated with mean telomere length.	Telomere length	2,917 European ancestry individuals	9,492 European ancestry individuals	3q26.2	3	169763483	TERC	RNU6-637P - TERC	ENSG00000206777	ENSG00000270141		43190	1037	rs12696304-G	rs12696304	0	12696304	regulatory_region_variant	1	0.30	4e-14	13.397940008672		0.11	[0.08-0.14] unit decrease	Affymetrix [405649]	N
2009-09-04	19680635	Alkelai A	2009-08-13	Psychopharmacology (Berl)	www.ncbi.nlm.nih.gov/pubmed/19680635	Genome-wide association study of antipsychotic-induced parkinsonism severity among schizophrenia patients.	Response to antipsychotic treatment	140 European ancestry cases, 117 European ancestry controls, 57 African American cases, 72 African American controls, 2 cases, 9 controls	NA	2q24.3	2	163461366	FIGN	RNU6-627P - FIGN	ENSG00000200902	ENSG00000182263		172270	132030	rs12476047-C	rs12476047	0	12476047	intergenic_variant	1	NR	3e-06	5.52287874528034		3.21	[1.97-5.25]	Affymetrix, Perlegen [495172]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	11q12.2	11	61830500	FADS2	FADS2			ENSG00000134824	NA	NA	rs1535-G	rs1535	0	1535	intron_variant	0	0.18	4e-07	6.39794000867204	(HDL)	0.03	[0.02-0.04] mmol/l decrease	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	11q12.2	11	61802358	FADS1	FADS1, FADS2			ENSG00000149485, ENSG00000134824	NA	NA	rs174546-A	rs174546	0	174546	3_prime_UTR_variant	0	0.18	6e-07	6.22184874961636	(HDL)	0.03	[0.02-0.04] mmol/l decrease	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	1p31.1	1	84295665	GLTP	AL359273.1 - SAMD13	ENSG00000199959	ENSG00000203943		18208	2701	rs1085093-?	rs1085093	0	1085093	intergenic_variant	1	0.45	3e-06	5.52287874528034	(HDL-cholesterol)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-A	rs7903146	0	7903146	intron_variant	0	0.30	7e-07	6.15490195998574	(T2D)	1.33	[1.19-1.49]	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	16p13.12	16	13882499	ERCC4	U95743.1 - ERCC4	ENSG00000262267	ENSG00000175595		102739	37658	rs2113334-?	rs2113334	0	2113334	intergenic_variant	1	0.41	3e-06	5.52287874528034	(WHR)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	16p13.3	16	2973604	PKMYT1	PKMYT1			ENSG00000127564	NA	NA	rs886427-?	rs886427	0	886427	intron_variant	0	0.28	6e-06	5.22184874961636	(WHR)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	13q13.3	13	38942490	STOML3	ANKRD26P2 - STOML3	ENSG00000235550	ENSG00000133115		6291	23435	rs9315632-?	rs9315632	0	9315632	intergenic_variant	1	0.28	3e-06	5.52287874528034	(WHR)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	11q12.2	11	61790331	C11orf10	TMEM258			ENSG00000134825	NA	NA	rs102275-?	rs102275	0	102275	non_coding_transcript_exon_variant	0	0.20	6e-07	6.22184874961636	(HDL)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	21q22.3	21	43359800	FLJ41733	LINC01679			ENSG00000237989	NA	NA	rs496300-G	rs496300	0	496300	intron_variant	0	0.16	4e-07	6.39794000867204	(HDL)	0.03	[0.02-0.05] mmol/l increase	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	12q24.11	12	109930396	GIT2	TCHP, GIT2			ENSG00000139437, ENSG00000139436	NA	NA	rs2292354-?	rs2292354	0	2292354	3_prime_UTR_variant	0	0.46	7e-06	5.15490195998574	(HDL)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	16q13	16	56935236	HERPUD1	HERPUD1			ENSG00000051108	NA	NA	rs2217332-?	rs2217332	0	2217332	missense_variant	0	0.19	3e-06	5.52287874528034	(HDL)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	18q21.32	18	60083782	PMAIP1	RNU6-567P - AC090771.2	ENSG00000252555	ENSG00000267686		65051	41251	rs12957347-?	rs12957347	0	12957347	intergenic_variant	1	0.36	7e-06	5.15490195998574	(Metabolic syndrome)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	1p22.2	1	91104132	ZNF644	RPL5P6 - HFM1	ENSG00000232393	ENSG00000162669		79328	156634	rs164898-?	rs164898	0	164898	regulatory_region_variant	1	0.27	6e-06	5.22184874961636	(WHR)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	9q34.11	9	127857358	ENG	ENG - AK1	ENSG00000106991	ENSG00000106992		2602	9128	rs7865146-A	rs7865146	0	7865146	intergenic_variant	1	0.37	1e-06	6	(DBP)	1.19	[0.71-1.67] mmHg decrease	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	1	0.36	1e-48	48	(HDL)	0.07	[0.06-0.08] mmol/l increase	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	8p21.3	8	20007664	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		40405	71450	rs2083637-G	rs2083637	0	2083637	intergenic_variant	1	0.24	2e-10	9.69897000433602	(HDL)	0.04	[0.02-0.05] mmol/l increase	Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	10q24.2	10	97877821	CRTAC1	CRTAC1			ENSG00000095713	NA	NA	rs531676-?	rs531676	0	531676	intron_variant	0	0.45	9e-06	5.04575749056067	(T2D)	NA		Illumina [308011]	N
2010-09-13	20694148	Zabaneh D	2010-08-04	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20694148	A genome-wide association study of the metabolic syndrome in Indian Asian men.	Metabolic syndrome	2,554 Indian Asian ancestry individuals	2,240 Indian Asian ancestry individuals	21q22.13	21	37560476	DYRK1A	DYRK1A - AP001407.1	ENSG00000157540	ENSG00000286717		34118	33501	rs2835810-?	rs2835810	0	2835810	intergenic_variant	1	0.37	6e-06	5.22184874961636	(WHR)	NA		Illumina [308011]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	4q21.23	4	85730311	ARHGAP24	ARHGAP24			ENSG00000138639	NA	NA	rs7660702-T	rs7660702	0	7660702	intron_variant	0	0.74	3e-17	16.5228787452803	(PR interval)	8.46	[6.50-10.42] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	3p22.2	3	38725184	SCN10A	SCN10A			ENSG00000185313	NA	NA	rs6795970-A	rs6795970	0	6795970	missense_variant	0	0.36	4e-09	8.39794000867204	(QRS duration)	5.17	[3.46-6.89] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	7q31.2	7	116546187	CAV1	CAV1, AC006159.1			ENSG00000105974, ENSG00000235427	NA	NA	rs3807989-A	rs3807989	0	3807989	intron_variant	0	0.40	7e-13	12.1549019599857	(PR interval)	6.4	[4.65-8.15] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	10q21.1	10	52464217	DKK1	LNCAROD			ENSG00000231131	NA	NA	rs1733724-T	rs1733724	0	1733724	intron_variant	0	0.21	7e-08	7.15490195998574	(QRS duration)	5.62	[3.58-7.66] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	14q11.2	14	23392602	MYH6	MYH6			ENSG00000197616	NA	NA	rs365990-G	rs365990	0	365990	missense_variant	0	0.34	9e-11	10.0457574905607	(HR)	5.25	[3.66-6.83] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	3p22.2	3	38725184	SCN10A	SCN10A			ENSG00000185313	NA	NA	rs6795970-A	rs6795970	0	6795970	missense_variant	0	0.36	1e-58	58	(PR interval)	14.81	[13.01-16.60] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	21q22.12	21	34507774	KCNE1	KCNE1			ENSG00000180509	NA	NA	rs727957-T	rs727957	0	727957	intron_variant	0	0.19	2e-12	11.698970004336	(QT interval)	11.7	[8.46-14.94] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	6q22.31	6	118359211	C6orf204	SLC35F1 - AL589993.1	ENSG00000196376	ENSG00000216809		41535	93258	rs11970286-T	rs11970286	0	11970286	intergenic_variant	1	0.54	8e-07	6.09691001300806	(QT interval)	6.19	[3.73-8.65] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	3p22.2	3	38547672	SCN5A	EXOG - SCN5A	ENSG00000157036	ENSG00000183873		5511	385	rs11129795-G	rs11129795	0	11129795	intergenic_variant	1	0.77	5e-10	9.30102999566398	(QRS complex)	8.24	[5.64-10.83] % s.d. decrease	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	12q24.21	12	114357638	TBX5	TBX5			ENSG00000089225	NA	NA	rs3825214-G	rs3825214	0	3825214	intron_variant	0	0.22	3e-13	12.5228787452803	(QRS duration)	7.35	[5.37-9.33] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	6p21.2	6	36655123	CDKN1A	RNU1-88P - Y_RNA	ENSG00000238554	ENSG00000265852		15451	17715	rs1321311-T	rs1321311	0	1321311	regulatory_region_variant	1	0.21	3e-10	9.52287874528034	(QRS duration)	6.52	[4.50-8.55] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	12q24.21	12	114357638	TBX5	TBX5			ENSG00000089225	NA	NA	rs3825214-G	rs3825214	0	3825214	intron_variant	0	0.22	3e-12	11.5228787452803	(PR interval)	7.36	[5.29-9.43] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	12q24.21	12	114357638	TBX5	TBX5			ENSG00000089225	NA	NA	rs3825214-G	rs3825214	0	3825214	intron_variant	0	0.22	1e-07	7	(QT interval)	5.88	[3.72-8.03] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	3p22.2	3	38551902	SCN5A	SCN5A			ENSG00000183873	NA	NA	rs12053903-T	rs12053903	0	12053903	intron_variant	0	0.72	1e-07	7	(PR interval)	6.59	[4.16-9.03] % s.d. decrease	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	1q23.3	1	162115895	NOS1AP	NOS1AP			ENSG00000198929	NA	NA	rs10494366-G	rs10494366	0	10494366	intron_variant	0	0.39	5e-22	21.301029995664	(QT interval)	12.2	[9.72-14.68] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	7q36.1	7	150970122	KCNH2	KCNH2			ENSG00000055118	NA	NA	rs3807375-T	rs3807375	0	3807375	intron_variant	0	0.35	5e-11	10.301029995664	(QT interval)	11.95	[8.39-15.51] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	11p15.5	11	2468112	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs12296050-T	rs12296050	0	12296050	intron_variant	0	0.15	8e-11	10.0969100130081	(QT interval)	13.16	[9.19-17.12] % s.d. increase	Illumina [306060]	N
2010-02-02	20062063	Holm H	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062063	Several common variants modulate heart rate, PR interval and QRS duration.	Electrocardiographic traits	Up to 12,670 European ancestry individuals	Up to 10,352 European ancestry individuals	16q21	16	58533334	NDRG4	CNOT1			ENSG00000125107	NA	NA	rs37062-A	rs37062	0	37062	intron_variant	0	0.72	1e-06	6	(QT interval)	6.09	[3.62-8.57] % s.d. increase	Illumina [306060]	N
2010-10-15	20876614	Yoon KA	2010-09-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20876614	A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.	Non-small cell lung cancer	621 Korean ancestry cases, 1,541 Korean ancestry controls	804 Korean ancestry cases, 1,470 Korean ancestry controls	17p13.2	17	6004123	NR	AC007846.2			ENSG00000285471	NA	NA	rs9303196-T	rs9303196	0	9303196	intron_variant	0	0.07	8e-06	5.09691001300806		1.43	[1.14-1.82]	Affymetrix [246758]	N
2010-10-15	20876614	Yoon KA	2010-09-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20876614	A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.	Non-small cell lung cancer	621 Korean ancestry cases, 1,541 Korean ancestry controls	804 Korean ancestry cases, 1,470 Korean ancestry controls	18p11.31	18	7042912	NR	LAMA1			ENSG00000101680	NA	NA	rs16951095-C	rs16951095	0	16951095	non_coding_transcript_exon_variant	0	0.78	7e-06	5.15490195998574		1.3	[1.10-1.54]	Affymetrix [246758]	N
2010-10-15	20876614	Yoon KA	2010-09-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20876614	A genome-wide association study reveals susceptibility variants for non-small cell lung cancer in the Korean population.	Non-small cell lung cancer	621 Korean ancestry cases, 1,541 Korean ancestry controls	804 Korean ancestry cases, 1,470 Korean ancestry controls	3q29	3	195137645	C3orf21	XXYLT1			ENSG00000173950	NA	NA	rs2131877-G	rs2131877	0	2131877	intron_variant	0	0.44	2e-08	7.69897000433602		1.3	[1.19-1.42]	Affymetrix [246758]	N
2010-09-15	20700438	Hsiung CA	2010-08-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20700438	The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.	Lung adenocarcinoma	584 East Asian ancestry cases, 585 East Asian ancestry controls	2,184 East Asian ancestry cases, 2,515 East Asian ancestry controls	5p15.33	5	1286401	TERT, CLPTM1L	TERT			ENSG00000164362	NA	NA	rs2736100-G	rs2736100	0	2736100	3_prime_UTR_variant	0	0.39	2e-22	21.698970004336		1.46	[1.35-1.57]	Illumina [457504]	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	4p16.3	4	945299	GAK	TMEM175			ENSG00000127419	NA	NA	rs6599388-T	rs6599388	0	6599388	intron_variant	0	0.31	4e-12	11.397940008672		1.16	[1.12-1.20]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	4p15.32	4	15735478	BST1	BST1			ENSG00000109743	NA	NA	rs11724635-A	rs11724635	0	11724635	intron_variant	0	0.56	1e-16	16		1.15	[1.11-1.19]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	12q12	12	40227006	LRRK2	LRRK2			ENSG00000188906	NA	NA	rs1491942-G	rs1491942	0	1491942	intron_variant	0	0.08	6e-14	13.2218487496164		1.27	[1.21-1.33]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	1q22	1	156060246	SYT11	LAMTOR2 - RAB25	ENSG00000116586	ENSG00000132698		1736	914	rs34372695-T	rs34372695	0	34372695	regulatory_region_variant	1	0.03	4e-12	11.397940008672		1.47	[1.35-1.59]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	2q21.3	2	134834811	ACMSD	CCNT2-AS1			ENSG00000224043	NA	NA	rs6710823-G	rs6710823	0	6710823	intron_variant	0	0.46	7e-09	8.15490195998574		1.1	[1.06-1.14]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	3q27.1	3	183103487	MCCC1, LAMP3	MCCC1			ENSG00000078070	NA	NA	rs11711441-G	rs11711441	0	11711441	intron_variant	0	0.86	8e-12	11.0969100130081		1.19	[1.13-1.25]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	4q22.1	4	89716450	SNCA	AC093866.1			ENSG00000251095	NA	NA	rs356219-G	rs356219	0	356219	intron_variant	0	0.39	2e-47	46.698970004336		1.29	[1.25-1.33]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	2q24.3	2	168260515	STK39	STK39 - RN7SL813P	ENSG00000198648	ENSG00000241074		12920	190809	rs2102808-C	rs2102808	0	2102808	intergenic_variant	1	0.12	4e-10	9.39794000867204		1.18	[1.12-1.24]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls				HLA-DRB5					NA	NA	6:32588205-A	6:32588205	0	NA		1	0.76	2e-14	13.698970004336		1.28	[1.22-1.34]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	12q24.31	12	122811747	CCDC62, HIP1R	CCDC62			ENSG00000130783	NA	NA	rs12817488-T	rs12817488	0	12817488	intron_variant	0	0.41	3e-13	12.5228787452803		1.14	[1.10-1.18]	Illumina [7689524] (imputed)	N
2015-04-20	21292315	Nalls MA	2011-02-01	Lancet	www.ncbi.nlm.nih.gov/pubmed/21292315	Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.	Parkinson's disease	5,333 European ancestry cases, 12,019 European ancestry controls	7,053 cases, 9,007 controls	17q21.31	17	45637484	MAPT	LINC02210, LINC02210-CRHR1, LINC02210-CRHR1			ENSG00000204650, ENSG00000263715, ENSG00000282456	NA	NA	rs2942168-G	rs2942168	0	2942168	non_coding_transcript_exon_variant	0	0.78	1e-28	28		1.27	[1.23-1.31]	Illumina [7689524] (imputed)	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	20q11.22	20	35326405	GDF5	UQCC1			ENSG00000101019	NA	NA	rs6060373-A	rs6060373	0	6060373	intron_variant	0	0.62	2e-17	16.698970004336		0.08	[0.05-0.11] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	4p15.31	4	17943217	LCORL	LCORL			ENSG00000178177	NA	NA	rs16896068-A	rs16896068	0	16896068	intron_variant	0	0.16	2e-13	12.698970004336		0.07	[0.03-0.11] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	12q14.3	12	65964567	HMGA2	HMGA2			ENSG00000149948	NA	NA	rs1042725-C	rs1042725	0	1042725	3_prime_UTR_variant	0	0.49	3e-18	17.5228787452803		0.05	[0.03-0.08] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	15q25.2	15	83899406	ADAMTSL3	ADAMTSL3			ENSG00000156218	NA	NA	rs10906982-A	rs10906982	0	10906982	intron_variant	0	0.52	2e-08	7.69897000433602		0.05	[0.02-0.07] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	1q42.13	1	227610249	ZNF678	ZNF678			ENSG00000181450	NA	NA	rs1390401-A	rs1390401	0	1390401	intron_variant	0	0.82	5e-09	8.30102999566398		0.04	[0.01-0.08] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	6q22.32	6	126645162	LOC387103	AL356534.1			ENSG00000286215	NA	NA	rs4549631-C	rs4549631	0	4549631	intron_variant	0	0.5	5e-13	12.301029995664		0.06	[0.03-0.08] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	9q22.32	9	95497421	PTCH1	PTCH1			ENSG00000185920	NA	NA	rs10512248-G	rs10512248	0	10512248	intron_variant	0	0.31	4e-11	10.397940008672		0.05	[0.02-0.07] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	1p12	1	118341350	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126		76861	272983	rs12735613-A	rs12735613	0	12735613	intergenic_variant	1	0.24	4e-11	10.397940008672		0.08	[0.05-0.11] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	13q14.3	13	50537219	DLEU7	DLEU1, DLEU7			ENSG00000176124, ENSG00000186047	NA	NA	rs3116602-G	rs3116602	0	3116602	intron_variant	0	0.21	7e-09	8.15490195998574		0.04	[0.00-0.07] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	1p34.2	1	41065199	SCMH1	SCMH1			ENSG00000010803	NA	NA	rs6686842-C	rs6686842	0	6686842	intron_variant	0	0.56	2e-08	7.69897000433602		0.05	[0.02-0.08] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	3q22.2	3	134514250	ANAPC13, CEP63	CEP63			ENSG00000182923	NA	NA	rs10935120-A	rs10935120	0	10935120	intron_variant	0	0.33	7e-08	7.15490195998574		0.06	[0.03-0.09] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	15q26.1	15	88816458	ACAN	ACAN			ENSG00000157766	NA	NA	rs8041863-A	rs8041863	0	8041863	intron_variant	0	0.47	8e-08	7.09691001300806		0.04	[0.01-0.06] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	2p16.1	2	55884174	EFEMP1	EFEMP1			ENSG00000115380	NA	NA	rs3791675-C	rs3791675	0	3791675	intron_variant	0	0.77	2e-12	11.698970004336		0.09	[0.05-0.12] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	18q21.1	18	49464790	DYM	DYM - PRR13P4	ENSG00000141627	ENSG00000264971		3443	5013	rs8099594-A	rs8099594	0	8099594	regulatory_region_variant	1	0.65	3e-07	6.52287874528034		0.05	[0.02-0.08] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	2q35	2	219079124	IHH	NHEJ1, AC068946.1			ENSG00000187736, ENSG00000280537	NA	NA	rs6724465-A	rs6724465	0	6724465	intron_variant	0	0.1	2e-08	7.69897000433602		0.06	[0.02-0.10] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	4q31.21	4	144721927	HHIP	HHIP, AC098588.3, AC098588.2			ENSG00000164161, ENSG00000285783, ENSG00000285713	NA	NA	rs6854783-A	rs6854783	0	6854783	intron_variant	0	0.43	2e-09	8.69897000433602		0.06	[0.03-0.08] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	12q22	12	93584728	SOCS2	SOCS2 - AC012085.1	ENSG00000120833	ENSG00000186076		1241	56094	rs11107116-G	rs11107116	0	11107116	regulatory_region_variant	1	0.77	6e-10	9.22184874961636		0.04	[0.01-0.07] s.d. decrease (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	6p21.31	6	34651116	C6orf106	ILRUN			ENSG00000196821	NA	NA	rs2814993-A	rs2814993	0	2814993	intron_variant	0	0.15	4e-12	11.397940008672		0.09	[0.05-0.13] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	7q21.2	7	92635096	CDK6	CDK6			ENSG00000105810	NA	NA	rs2282978-C	rs2282978	0	2282978	intron_variant	0	0.33	8e-23	22.0969100130081		0.09	[0.06-0.12] s.d. increase (males)	Affymetrix [402951]	N
2008-09-17	18391952	Weedon MN	2008-04-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18391952	Genome-wide association analysis identifies 20 loci that influence adult height.	Height	13,665 European ancestry individuals	16,482 European ancestry individuals	3q23	3	141375367	ZBTB38	ZBTB38			ENSG00000177311	NA	NA	rs6440003-A	rs6440003	0	6440003	intron_variant	0	0.44	2e-24	23.698970004336		0.07	[0.04-0.09] s.d. increase (males)	Affymetrix [402951]	N
2011-11-09	22010048	Wu X	2011-10-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22010048	A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.	Renal cell carcinoma	894 European ancestry cases, 1,516 European ancestry controls	3,772 European ancestry cases, 8,505 European ancestry controls	12p11.23	12	26300350	ITPR2	AC022509.2, AC022509.1			ENSG00000256234, ENSG00000255750	NA	NA	rs718314-?	rs718314	0	718314	intron_variant	0	NR	9e-10	9.04575749056067		1.19	[1.13-1.26]	Illumina [533191]	N
2011-11-09	22010048	Wu X	2011-10-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22010048	A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.	Renal cell carcinoma	894 European ancestry cases, 1,516 European ancestry controls	3,772 European ancestry cases, 8,505 European ancestry controls	11q13.3	11	69419726	NR	AP005233.1 - AP000439.2	ENSG00000259854	ENSG00000255980		2894	5964	rs4980785-?	rs4980785	0	4980785	regulatory_region_variant	1	NR	2e-06	5.69897000433602		NA		Illumina [533191]	N
2011-11-09	22010048	Wu X	2011-10-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22010048	A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.	Renal cell carcinoma	894 European ancestry cases, 1,516 European ancestry controls	3,772 European ancestry cases, 8,505 European ancestry controls	6q22.31	6	118486684	NR	CEP85L			ENSG00000111860	NA	NA	rs25422-?	rs25422	0	25422	intron_variant	0	NR	5e-06	5.30102999566398		NA		Illumina [533191]	N
2010-02-08	20081856	McMahon FJ	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081856	Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.	Major mood disorders	6,686 European ancestry cases, 9,068 European ancestry controls	1,930 European ancestry cases, 2,747 European ancestry controls	3p21.1	3	52550771	PBRM1	SMIM4, PBRM1			ENSG00000168273, ENSG00000163939	NA	NA	rs2251219-?	rs2251219	0	2251219	synonymous_variant	0	0.59	2e-09	8.69897000433602		1.14	[1.09-1.18]	Affymetrix, Illumina, Perlegen [~ 2100000] (imputed)	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6q23.3	6	135111414	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		8358	69894	rs9494145-C	rs9494145	0	9494145	intergenic_variant	1	0.24	3e-15	14.5228787452803	(MCV)	0.98	[0.74-1.22] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6q23.3	6	135131014	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		27958	50294	rs6569992-A	rs6569992	0	6569992	intergenic_variant	1	0.20	3e-08	7.52287874528034	(MCV)	0.75	[0.48-1.02] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6q23.3	6	135131014	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		27958	50294	rs6569992-A	rs6569992	0	6569992	intergenic_variant	1	0.20	6e-09	8.22184874961636	(RBC count)	0.07	[0.05-0.09] unit decrease	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.26	1e-14	14	(RBC count)	0.09	[0.07-0.11] unit decrease	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-A	rs855791	0	855791	missense_variant	0	0.44	1e-12	12	(MCH)	0.29	[0.21-0.37] unit decrease	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	22q12.3	22	37073551	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs4820268-G	rs4820268	0	4820268	missense_variant	0	0.47	1e-12	12	(MCHC)	0.09	[0.07-0.11] unit decrease	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.24	1e-15	15	(MCH)	0.38	[0.29-0.47] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	0.06	6e-07	6.22184874961636	(MCV)	1.09	[NR] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6q23.3	6	135131014	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		27958	50294	rs6569992-A	rs6569992	0	6569992	intergenic_variant	1	0.19	1e-08	8	(MCH)	0.3	[0.19-0.40] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	0.06	3e-09	8.52287874528034	(MCH)	0.49	[NR] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-A	rs855791	0	855791	missense_variant	0	0.44	5e-09	8.30102999566398	(MCV)	0.62	[0.41-0.83] unit decrease	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	0.06	3e-09	8.52287874528034	(MCH)	0.49	[0.33-0.65] unit increase	Illumina [489421]	N
2010-10-15	20927387	Kullo IJ	2010-09-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20927387	A genome-wide association study of red blood cell traits using the electronic medical record.	Red blood cell traits	3,012 European ancestry individuals	NA	6p22.2	6	25821542	SLC17A1	SLC17A1			ENSG00000124568	NA	NA	rs17342717-T	rs17342717	0	17342717	intron_variant	0	0.10	5e-08	7.30102999566398	(MCH)	0.38	[0.24-0.52] unit increase	Illumina [489421]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	10q11.21	10	44824206	AL139 119.2	TMEM72-AS1			ENSG00000224812	NA	NA	rs7911712-A	rs7911712	0	7911712	intron_variant	0	0.15	6e-06	5.22184874961636	(quantitative)	2.05	[NR] HU increase	Illumina [499578]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	10p11.22	10	33942347	PARD3	LINC02629 - PARD3	ENSG00000223470	ENSG00000148498		24543	167213	rs7905537-A	rs7905537	0	7905537	intergenic_variant	1	0.75	8e-07	6.09691001300806	(quantitative)	1.85	[NR] HU increase	Illumina [499578]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	8p23.2	8	2882980	CSMD1	AC246817.1			ENSG00000253853	NA	NA	rs641525-T	rs641525	0	641525	intergenic_variant	0	0.95	5e-07	6.30102999566398	(qualitative)	2.19	[NR]	Illumina [499578]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	7p12.1	7	52404754	AC006320.2	AC006320.1 - AC006459.1	ENSG00000253028	ENSG00000286908		135185	88398	rs1012036-C	rs1012036	0	1012036	intergenic_variant	1	0.77	5e-06	5.30102999566398	(qualitative)	1.47	[NR]	Illumina [499578]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	5p13.3	5	30661466	CDH6	AC099517.1			ENSG00000287176	NA	NA	rs9292394-T	rs9292394	0	9292394	intron_variant	0	0.78	2e-06	5.69897000433602	(quantitative)	1.83	[NR] HU increase	Illumina [499578]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	12p11.21	12	32227567	BICD1	BICD1, AC016954.1			ENSG00000151746, ENSG00000258134	NA	NA	rs10844154-C	rs10844154	0	10844154	non_coding_transcript_exon_variant	0	0.58	6e-07	6.22184874961636	(qualitative)	1.46	[NR]	Illumina [499578]	N
2010-09-22	20709820	Kong X	2010-08-13	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/20709820	Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.	Emphysema-related traits	2,383 European ancestry cases	NA	10p15.3	10	1588626	ADARB2	ADARB2			ENSG00000185736	NA	NA	rs2999399-T	rs2999399	0	2999399	intron_variant	0	0.76	6e-06	5.22184874961636	(qualitative)	1.47	[NR]	Illumina [499578]	N
2009-10-23	19812673	Weiss LA	2009-10-08	Nature	www.ncbi.nlm.nih.gov/pubmed/19812673	A genome-wide linkage and association scan reveals novel loci for autism.	Autism	1,553 cases from 1,031 families	2,073 trios	5p15.31	5	9623510	SEMA5A, TAS2R1	AC026787.1			ENSG00000248525	NA	NA	rs10513025-?	rs10513025	0	10513025	non_coding_transcript_exon_variant	0	NR	2e-07	6.69897000433602		1.81	[NR]	Affymetrix [~ 365000]	N
2009-10-23	19812673	Weiss LA	2009-10-08	Nature	www.ncbi.nlm.nih.gov/pubmed/19812673	A genome-wide linkage and association scan reveals novel loci for autism.	Autism	1,553 cases from 1,031 families	2,073 trios	5q13.3	5	77121217	NR	ZBED3-AS1, AC022414.1, AC008581.2			ENSG00000250802, ENSG00000284762, ENSG00000285000	NA	NA	rs6453278-?	rs6453278	0	6453278	intron_variant	0	NR	5e-06	5.30102999566398		1.25	[NR]	Affymetrix [~ 365000]	N
2009-10-06	19786962	Roeske D	2009-09-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19786962	First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.	Speech perception in dyslexia	200 European ancestry cases	186 European ancestry cases	10q26.3	10	130193981	NR	GLRX3 - LINC02646	ENSG00000108010	ENSG00000236303		9460	19507	rs4751178-G	rs4751178	0	4751178	regulatory_region_variant	1	NR	7e-06	5.15490195998574	(MMNb)	NA		Illumina [297086]	N
2009-10-06	19786962	Roeske D	2009-09-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19786962	First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.	Speech perception in dyslexia	200 European ancestry cases	186 European ancestry cases	4q32.1	4	156077389	PDGFC, CTSO, TDO2	FTH1P21 - AC096736.3	ENSG00000249013	ENSG00000251511		70401	508590	rs4234898-T	rs4234898	0	4234898	intergenic_variant	1	NR	5e-08	7.30102999566398	(MMNb)	NA		Illumina [297086]	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	1q23.1	1	158615625	SPTA1	SPTA1			ENSG00000163554	NA	NA	rs2779116-T	rs2779116	0	2779116	intron_variant	0	0.27	3e-09	8.52287874528034		0.02	[0.01-0.03] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	2q31.1	2	168934928	G6PC2, ABCB11	ABCB11			ENSG00000073734	NA	NA	rs552976-G	rs552976	0	552976	intron_variant	0	0.64	8e-18	17.0969100130081		0.05	[0.04-0.06] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	7p13	7	44189469	GCK	GCK			ENSG00000106633	NA	NA	rs1799884-T	rs1799884	0	1799884	intron_variant	0	0.18	1e-20	20		0.04	[0.03-0.05] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	11q14.3	11	92940662	MTNR1B	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		2996	25135	rs1387153-T	rs1387153	0	1387153	intergenic_variant	1	0.28	4e-11	10.397940008672		0.03	[0.02-0.04] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	8p11.21	8	41772887	ANK1	ANK1			ENSG00000029534	NA	NA	rs4737009-A	rs4737009	0	4737009	intron_variant	0	0.24	6e-12	11.2218487496164		0.03	[0.02-0.04] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	17q25.3	17	82727657	FN3K	FN3KRP			ENSG00000141560	NA	NA	rs1046896-T	rs1046896	0	1046896	3_prime_UTR_variant	0	0.31	2e-26	25.698970004336		0.04	[0.03-0.05] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-A	rs855791	0	855791	missense_variant	0	0.42	3e-14	13.5228787452803		0.03	[0.02-0.04] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	8p11.21	8	41691676	ANK1	ANK1			ENSG00000029534	NA	NA	rs6474359-T	rs6474359	0	6474359	intron_variant	0	0.97	1e-08	8		0.06	[0.04-0.08] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-G	rs1800562	0	1800562	missense_variant	0	0.94	3e-20	19.5228787452803		0.06	[0.05-0.07] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	10q22.1	10	69333636	HK1	HK1			ENSG00000156515	NA	NA	rs16926246-C	rs16926246	0	16926246	intron_variant	0	0.90	3e-54	53.5228787452803		0.09	[0.08-0.10] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-10-07	20858683	Soranzo N	2010-09-21	Diabetes	www.ncbi.nlm.nih.gov/pubmed/20858683	Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.	Glycated hemoglobin levels	up to 46,368 European ancestry individuals	NA	13q34	13	112677554	ATP11A, TUBGCP3	ATP11AUN			ENSG00000197595	NA	NA	rs7998202-G	rs7998202	0	7998202	intron_variant	0	0.14	5e-09	8.30102999566398		0.03	[0.02-0.04] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2015-04-24	21239051	Reilly MP	2011-01-14	Lancet	www.ncbi.nlm.nih.gov/pubmed/21239051	Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.	Coronary artery disease	1,808 European ancestry cases, 915 European ancestry controls	10,585 European ancestry cases, 6,468 European ancestry controls	15q25.1	15	78787892	ADAMTS7	ADAMTS7			ENSG00000136378	NA	NA	rs1994016-C	rs1994016	0	1994016	intron_variant	0	0.60	5e-13	12.301029995664		1.19	[1.13-1.24]	Affymetrix, Illumina [> 2400000] (imputed)	N
2015-04-24	21239051	Reilly MP	2011-01-14	Lancet	www.ncbi.nlm.nih.gov/pubmed/21239051	Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.	Coronary artery disease	1,808 European ancestry cases, 915 European ancestry controls	10,585 European ancestry cases, 6,468 European ancestry controls	1p13.3	1	109275908	SORT1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		157	3648	rs646776-T	rs646776	0	646776	intergenic_variant	1	0.79	8e-11	10.0969100130081		1.33	[1.22-1.44]	Affymetrix, Illumina [> 2400000] (imputed)	N
2015-04-24	21239051	Reilly MP	2011-01-14	Lancet	www.ncbi.nlm.nih.gov/pubmed/21239051	Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.	Coronary artery disease	1,808 European ancestry cases, 915 European ancestry controls	10,585 European ancestry cases, 6,468 European ancestry controls	9p21.3	9	22098575	ANRIL, CDKN2A, CDKN2B	CDKN2B-AS1			ENSG00000240498	NA	NA	rs4977574-G	rs4977574	0	4977574	intron_variant	0	0.53	5e-14	13.301029995664		1.3	[1.22-1.39]	Affymetrix, Illumina [> 2400000] (imputed)	N
2015-04-24	21239051	Reilly MP	2011-01-14	Lancet	www.ncbi.nlm.nih.gov/pubmed/21239051	Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.	Myocardial infarction in coronary artery disease	4,572 European ancestry cases, 2,739 European ancestry controls	1,211 European ancestry cases, 905 European ancestry controls	9q34.2	9	133266790	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs514659-C	rs514659	0	514659	intron_variant	0	0.37	8e-09	8.09691001300806		1.21	[1.13-1.29]	Affymetrix, Illumina [up to 2400000] (imputed)	N
2010-10-05	20849430	Franklin CS	2010-09-16	Ann Hum Genet	www.ncbi.nlm.nih.gov/pubmed/20849430	The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis.	Glycated hemoglobin levels	1,782 European ancestry individuals	NA	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-C	rs7903146	0	7903146	intron_variant	0	0.72	1e-07	7		0.05	[0.02-0.08] % HbA1C decrease	Illumina [256587]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	4q32.2	4	161329780	intergenic	RPS14P7 - AC104793.1	ENSG00000242635	ENSG00000249568		510911	49173	rs4470583-A	rs4470583	0	4470583	intergenic_variant	1	NR	4e-07	6.39794000867204		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	10p12.31	10	20253705	PLXDC2	PLXDC2			ENSG00000120594	NA	NA	rs1571942-C	rs1571942	0	1571942	intron_variant	0	NR	3e-07	6.52287874528034		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	10q11.22	10	48491914	ARHGAP22	ARHGAP22			ENSG00000128805	NA	NA	rs4838605-C	rs4838605	0	4838605	intron_variant	0	NR	2e-09	8.69897000433602		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	10q21.1	10	57429418	intergenic	MIR3924 - AL731534.1	ENSG00000264747	ENSG00000235810		124859	83739	rs4462262-C	rs4462262	0	4462262	intergenic_variant	1	NR	9e-08	7.04575749056067		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	1p32.1	1	58696476	MYSM1	MYSM1			ENSG00000162601	NA	NA	rs2811893-T	rs2811893	0	2811893	intron_variant	0	NR	3e-07	6.52287874528034		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	5q15	5	94221997	intergenic	KIAA0825			ENSG00000185261	NA	NA	rs17376456-A	rs17376456	0	17376456	intron_variant	0	NR	3e-15	14.5228787452803		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	10p12.31	10	20304158	intergenic	PLXDC2 - AMD1P1	ENSG00000120594	ENSG00000228339		14302	45891	rs12219125-T	rs12219125	0	12219125	intergenic_variant	1	NR	9e-09	8.04575749056067		NA		Illumina [~ 550000]	N
2015-05-23	21310492	Huang YC	2011-02-08	Ophthalmology	www.ncbi.nlm.nih.gov/pubmed/21310492	Genome-wide association study of diabetic retinopathy in a Taiwanese population.	Diabetic retinopathy	174 Han Chinese ancestry Type 2 diabetes cases, 575 Han Chinese ancestry Type 2 diabetes controls, 100 Han Chinese ancestry non-diabetic controls	NA	13q32.1	13	96299179	HS6ST3	HS6ST3			ENSG00000185352	NA	NA	rs2038823-C	rs2038823	0	2038823	intron_variant	0	NR	5e-11	10.301029995664		NA		Illumina [~ 550000]	N
2015-05-15	21347284	Smith JG	2011-02-10	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21347284	Genome-wide association studies of the PR interval in African Americans.	PR interval	6,247 African American individuals	2,022 African American individuals	3p22.2	3	38582762	SCN5A	SCN5A			ENSG00000183873	NA	NA	rs3922844-C	rs3922844	0	3922844	intron_variant	0	0.41	3e-23	22.5228787452803		5.11	[4.11-6.11] unit increase	Affymetrix [2801419] (imputed)	N
2015-05-15	21347284	Smith JG	2011-02-10	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21347284	Genome-wide association studies of the PR interval in African Americans.	PR interval	6,247 African American individuals	2,022 African American individuals	3p22.2	3	38757345	SCN10A	SCN10A			ENSG00000185313	NA	NA	rs6798015-C	rs6798015	0	6798015	intron_variant	0	0.14	2e-12	11.698970004336		4.98	[3.61-6.35] unit increase	Affymetrix [2801419] (imputed)	N
2015-05-15	21347284	Smith JG	2011-02-10	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21347284	Genome-wide association studies of the PR interval in African Americans.	PR interval	6,247 African American individuals	2,022 African American individuals	2p14	2	66537865	MEIS1	MEIS1			ENSG00000143995	NA	NA	rs10865355-A	rs10865355	0	10865355	intron_variant	0	0.43	3e-09	8.52287874528034		2.89	[1.95-3.83] unit increase	Affymetrix [2801419] (imputed)	N
2015-05-15	21347284	Smith JG	2011-02-10	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21347284	Genome-wide association studies of the PR interval in African Americans.	PR interval	6,247 African American individuals	2,022 African American individuals	12q24.21	12	114362169	TBX5	TBX5			ENSG00000089225	NA	NA	rs7312625-A	rs7312625	0	7312625	intron_variant	0	0.71	7e-09	8.15490195998574		3.23	[2.15-4.31] unit decrease	Affymetrix [2801419] (imputed)	N
2015-05-15	21347284	Smith JG	2011-02-10	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21347284	Genome-wide association studies of the PR interval in African Americans.	PR interval	6,247 African American individuals	2,022 African American individuals	3p22.2	3	38606571	SCN5A	SCN5A			ENSG00000183873	NA	NA	rs6599222-C	rs6599222	0	6599222	intron_variant	0	0.23	2e-08	7.69897000433602		3.4	[2.20-4.60] unit increase	Affymetrix [2801419] (imputed)	N
2011-04-13	21441931	Okamoto K	2011-03-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21441931	Common variation in GPC5 is associated with acquired nephrotic syndrome.	Nephrotic syndrome (acquired)	195 Japanese ancestry cases, 1,546 Japanese ancestry controls	662 Japanese ancestry cases, 4,919 Japanese ancestry controls	13q31.3	13	91551559	GPC5	GPC5			ENSG00000179399	NA	NA	rs16946160-A	rs16946160	0	16946160	intron_variant	0	0.17	3e-07	6.52287874528034		1.39	[1.22-1.57]	Perlegen [205203]	N
2011-04-13	21441931	Okamoto K	2011-03-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21441931	Common variation in GPC5 is associated with acquired nephrotic syndrome.	Nephrotic syndrome (acquired)	195 Japanese ancestry cases, 1,546 Japanese ancestry controls	662 Japanese ancestry cases, 4,919 Japanese ancestry controls	20q13.13	20	48150492	SULF2, PREX1	AL136102.1 - AL121888.2	ENSG00000287107	ENSG00000288083		13648	114477	rs11086243-T	rs11086243	0	11086243	intergenic_variant	1	0.23	3e-06	5.52287874528034		1.37	[1.20-1.57]	Perlegen [205203]	N
2008-06-16	16648850	Arking DE	2006-04-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/16648850	A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.	QT interval	100 European ancestry > 445ms female individuals, 100 European ancestry < 386ms female individuals	200 European ancestry > 85th pct female individuals, 200 European ancestry < 15th pct female individuals, 4,451 European ancestry individuals	1q23.3	1	162115895	NOS1AP	NOS1AP			ENSG00000198929	NA	NA	rs10494366-?	rs10494366	0	10494366	intron_variant	0		1e-10	10		NA		Affymetrix [88500]	N
2010-09-10	20668459	Kim HN	2010-07-29	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/20668459	Genetic variants that affect length/height in infancy/early childhood in Vietnamese-Korean families.	Height	518 Vietnamese-Korean ancestry individuals from 165 families	NA	16q23.2	16	79551124	MAF	AC084064.1 - MAF	ENSG00000261472	ENSG00000178573		34831	34719	rs7498403-C	rs7498403	0	7498403	intergenic_variant	1	0.11	5e-06	5.30102999566398		NA		Illumina [269888]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	2q23.1	2	148800291	EPC2	EPC2 - RNU2-9P	ENSG00000135999	ENSG00000222126		12722	25400	rs2121433-?	rs2121433	0	2121433	intergenic_variant	1	NR	1e-06	6	(t-tau)	NA		Illumina [322557]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	19q13.32	19	44892009	TOMM40	TOMM40			ENSG00000130204	NA	NA	rs157580-?	rs157580	0	157580	intron_variant	0	NR	1e-06	6	(AB1-42)	NA		Illumina [322557]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	22q13.2	22	41822852	CCDC134	CCDC134			ENSG00000100147	NA	NA	rs7364180-?	rs7364180	0	7364180	intron_variant	0	NR	1e-06	6	(AB1-42)	NA		Illumina [322557]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	2q23.1	2	148810827	EPC2	EPC2 - RNU2-9P	ENSG00000135999	ENSG00000222126		23258	14864	rs4499362-?	rs4499362	0	4499362	intergenic_variant	1	NR	1e-06	6	(t-tau/AB1-42)	NA		Illumina [322557]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	19q13.32	19	44892362	TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	0	NR	1e-06	6	(p-tau181p/AB1-42, t-tau/AB1-42)	NA		Illumina [322557]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	19q13.32	19	44908684	APOE	APOE			ENSG00000130203	NA	NA	rs429358-?	rs429358	0	429358	missense_variant	0	NR	1e-06	6	(AB1-42, p-tau181p, p-tau181p/AB1-42, t-tau/AB1-42)	NA		Illumina [322557]	N
2011-01-12	21123754	Kim S	2010-12-01	Neurology	www.ncbi.nlm.nih.gov/pubmed/21123754	Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort.	Alzheimer's disease biomarkers	96 European ancestry Alzheimer disease cases, 176 European ancestry individuals with mild cognitive impairment, 102 European ancestry controls	NA	19q13.32	19	44911194	LOC100129500	AC011481.3			ENSG00000280087	NA	NA	rs439401-?	rs439401	0	439401	non_coding_transcript_exon_variant	0	NR	1e-06	6	(AB1-42)	NA		Illumina [322557]	N
2009-02-05	19081515	Mead S	2008-12-11	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/19081515	Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.	Creutzfeldt-Jakob disease	117 European ancestry cases, 3,083 European ancestry controls	2 European ancestry vCJD cases, 506 Oceania ancestry sCJD cases, 28 Oceania ancestry iCJD cases, 151 Oceania ancestry Kuru cases, 125 Oceania ancestry Kuru resistant cases, 3,608 European ancestry controls, 562 Oceania ancestry controls	8q21.13	8	79315213	STMN2	AC138646.1 - AC100870.1	ENSG00000253659	ENSG00000253391		262	204932	rs1460163-A	rs1460163	0	1460163	intergenic_variant	1	NR	6e-08	7.22184874961636		NA		Affymetrix [288908]	N
2009-02-05	19081515	Mead S	2008-12-11	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/19081515	Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.	Creutzfeldt-Jakob disease	117 European ancestry cases, 3,083 European ancestry controls	2 European ancestry vCJD cases, 506 Oceania ancestry sCJD cases, 28 Oceania ancestry iCJD cases, 151 Oceania ancestry Kuru cases, 125 Oceania ancestry Kuru resistant cases, 3,608 European ancestry controls, 562 Oceania ancestry controls	20p13	20	4699605	PRNP	PRNP			ENSG00000171867	NA	NA	rs1799990-A	rs1799990	0	1799990	missense_variant	0	NR	2e-21	20.698970004336		NA		Affymetrix [288908]	N
2013-10-18	20308991	Kim S	2010-03-23	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20308991	Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.	Brain cytoarchitecture	14 European ancestry bipolar cases, 15 European ancestry depression cases, 13 European ancestry schizophrenia cases, 14 European ancestry controls	NA	5q22.2	5	113379677	MCC	AC079465.1, MCC			ENSG00000232633, ENSG00000171444	NA	NA	rs6594713-?	rs6594713	0	6594713	intron_variant	0	0.21	2e-06	5.69897000433602		NA		Affymetrix [309531]	N
2013-10-18	20308991	Kim S	2010-03-23	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20308991	Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.	Brain cytoarchitecture	14 European ancestry bipolar cases, 15 European ancestry depression cases, 13 European ancestry schizophrenia cases, 14 European ancestry controls	NA	2q33.1	2	198737201	SATB2, PLCL1	AC019330.1			ENSG00000225421	NA	NA	rs11893063-?	rs11893063	0	11893063	intron_variant	0	0.46	2e-06	5.69897000433602		NA		Affymetrix [309531]	N
2010-10-05	20835239	Solouki AM	2010-09-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20835239	A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14.	Refractive error	5,328 European ancestry individuals	10,280 European ancestry individuals	15q14	15	34713872	GJD2, GOLGA8B, ACTC1	LINC02252 - GJD2	ENSG00000261304	ENSG00000159248		42777	37160	rs634990-C	rs634990	0	634990	intergenic_variant	1	0.47	2e-14	13.698970004336		0.23	[0.228-0.232] diopter increase	Illumina [~ 2500000] (imputed)	N
2009-02-28	19187332	Kim SH	2009-02-01	Clin Exp Allergy	www.ncbi.nlm.nih.gov/pubmed/19187332	Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.	Asthma (toluene diisocyanate-induced)	84 Korean ancestry cases, 263 Korean ancestry controls	NA	10q21.3	10	66328750	CTNNA3	CTNNA3			ENSG00000183230	NA	NA	rs10762058-G	rs10762058	0	10762058	intron_variant	0	0.25	6e-06	5.22184874961636		5	[2.36-10.6]	Affymetrix [312978]	N
2009-02-28	19187332	Kim SH	2009-02-01	Clin Exp Allergy	www.ncbi.nlm.nih.gov/pubmed/19187332	Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.	Asthma (toluene diisocyanate-induced)	84 Korean ancestry cases, 263 Korean ancestry controls	NA	13q12.13	13	26841536	intergenic	GPR12 - FGFR1OP2P1	ENSG00000132975	ENSG00000230256		80750	63826	rs9319321-T	rs9319321	0	9319321	intergenic_variant	1	0.29	3e-06	5.52287874528034		5.2	[2.47-10.92]	Affymetrix [312978]	N
2009-02-28	19187332	Kim SH	2009-02-01	Clin Exp Allergy	www.ncbi.nlm.nih.gov/pubmed/19187332	Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis.	Asthma (toluene diisocyanate-induced)	84 Korean ancestry cases, 263 Korean ancestry controls	NA	9p21.3	9	20098713	intergenic	AL591222.3 - AL512635.1	ENSG00000277711	ENSG00000237434		130719	232733	rs16937883-G	rs16937883	0	16937883	intergenic_variant	1	0.02	7e-06	5.15490195998574		5.29	[2.41-11.61]	Affymetrix [312978]	N
2008-09-09	17668382	Salonen JT	2007-06-26	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/17668382	Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.	Type 2 diabetes	201 Finland founder cases, 200 Finland founder controls, 200 Ashkenazi Jewish cases, 197 Ashkenazi Jewish controls, 99 European ancestry cases, 100 European ancestry controls	2,573 European ancestry cases, 2,776 European ancestry controls	2q12.1	2	105221141	intergenic	LINC01918 - GPR45	ENSG00000226508	ENSG00000135973		75717	20602	rs6712932-?	rs6712932	0	6712932	intergenic_variant	1	NR	6e-06	5.22184874961636		1.52	[1.27-1.82]	Illumina [315917]	N
2008-09-09	17668382	Salonen JT	2007-06-26	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/17668382	Type 2 diabetes whole-genome association study in four populations: the DiaGen consortium.	Type 2 diabetes	201 Finland founder cases, 200 Finland founder controls, 200 Ashkenazi Jewish cases, 197 Ashkenazi Jewish controls, 99 European ancestry cases, 100 European ancestry controls	2,573 European ancestry cases, 2,776 European ancestry controls	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-A	rs7903146	0	7903146	intron_variant	0	NR	5e-08	7.30102999566398		1.71	[1.41-2.08]	Illumina [315917]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	11p15.4	11	5209677	NA	AC104389.2 - AC104389.7	ENSG00000224091	ENSG00000285498		2369	14632	rs7120391-C	rs7120391	0	7120391	intergenic_variant	1	0.12	5e-09	8.30102999566398	(MCHC)	0.3	[0.20-0.40] unit increase	Illumina [907954]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	Xq28	X	154536002	G6PD	G6PD			ENSG00000160211	NA	NA	rs1050828-A	rs1050828	0	1050828	missense_variant	0	0.12	9e-09	8.04575749056067	(MCH)	0.72	[0.48-0.96] pg increase	Illumina [907954]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	16p13.3	16	264781	ITFG3	FAM234A			ENSG00000167930	NA	NA	rs9924561-T	rs9924561	0	9924561	intron_variant	0	0.10	5e-29	28.301029995664	(MCV)	3.57	[2.94-4.20] fL decrease	Illumina [907954]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	16p13.3	16	264781	ITFG3	FAM234A			ENSG00000167930	NA	NA	rs9924561-T	rs9924561	0	9924561	intron_variant	0	0.10	8e-36	35.0969100130081	(MCH)	1.56	[1.32-1.80] pg decrease	Illumina [907954]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	16p13.3	16	264781	ITFG3	FAM234A			ENSG00000167930	NA	NA	rs9924561-T	rs9924561	0	9924561	intron_variant	0	0.10	9e-17	16.0457574905607	(MCHC)	0.47	[0.35-0.59] unit decrease	Illumina [907954]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	Xq28	X	154536002	G6PD	G6PD			ENSG00000160211	NA	NA	rs1050828-A	rs1050828	0	1050828	missense_variant	0	0.12	4e-13	12.397940008672	(RBC count)	0.2	[0.14-0.26] x10^12/L decrease	Illumina [907954]	N
2013-11-13	23696099	Ding K	2013-05-20	G3 (Bethesda)	www.ncbi.nlm.nih.gov/pubmed/23696099	Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.	Red blood cell traits	1904 African American individuals	411 African American individuals	Xq28	X	154536002	G6PD	G6PD			ENSG00000160211	NA	NA	rs1050828-A	rs1050828	0	1050828	missense_variant	0	0.12	1e-14	14	(MCV)	2.46	[1.83-3.09] fL increase	Illumina [907954]	N
2009-02-04	19107115	Muglia P	2008-12-23	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19107115	Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts.	Major depressive disorder	1,359 European ancestry cases, 1,782 European ancestry controls	NA	12p13.32	12	4009151	CCND2	AC005842.1 - AC084375.1	ENSG00000256862	ENSG00000256969		98769	3751	rs4238010-G	rs4238010	0	4238010	intergenic_variant	1	0.02	6e-06	5.22184874961636		1.72		Affymetrix, Illumina [494678] (imputed)	N
2013-09-21	20117844	Brynedal B	2010-02-01	J Neuroimmunol	www.ncbi.nlm.nih.gov/pubmed/20117844	MGAT5 alters the severity of multiple sclerosis.	Multiple sclerosis (severity)	1,040 European ancestry cases	873 European ancestry cases	2q21.3	2	134311223	MGAT5	MGAT5			ENSG00000152127	NA	NA	rs4953911-T	rs4953911	0	4953911	intron_variant	0	0.36	2e-07	6.69897000433602		NA		Affymetrix [105035]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	6q25.3	6	155608667	intergenic	NOX3 - RNU7-152P	ENSG00000074771	ENSG00000238789		152828	46296	rs35229355-T	rs35229355	0	35229355	intergenic_variant	1	NR	5e-06	5.30102999566398		7.24	[2.46-21.30]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	10q26.12	10	121141109	intergenic	RPL19P16 - LINC01153	ENSG00000236762	ENSG00000227143		7386	37591	rs2901286-A	rs2901286	0	2901286	intergenic_variant	1	NR	4e-06	5.39794000867204		4.66	[1.58-13.7]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	20q13.12	20	47579861	NCOA3	NCOA3			ENSG00000124151	NA	NA	rs6125048-T	rs6125048	0	6125048	intron_variant	0	NR	2e-06	5.69897000433602		2.73	[1.08-6.88]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	4q31.21	4	141788570	IL15	IL15 - INPP4B	ENSG00000164136	ENSG00000109452		54583	234590	rs17007695-C	rs17007695	0	17007695	intergenic_variant	1	NR	9e-07	6.04575749056067		2.67	[1.53-4.68]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	2q33.1	2	200157231	C2orf47	AC004464.1 - SPATS2L	ENSG00000287027	ENSG00000196141		57206	148650	rs1569175-T	rs1569175	0	1569175	intergenic_variant	1	NR	9e-07	6.04575749056067		2.73	[1.52-4.93]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	7p21.2	7	14406292	DGKB	DGKB			ENSG00000136267	NA	NA	rs6971925-T	rs6971925	0	6971925	intron_variant	0	NR	3e-06	5.52287874528034		13.91	[2.72-70.92]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	7p14.1	7	37226747	ELMO1	ELMO1			ENSG00000155849	NA	NA	rs4723619-C	rs4723619	0	4723619	intron_variant	0	NR	3e-06	5.52287874528034		3.01	[1.50-6.03]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	10p14	10	8108750	intergenic	GATA3 - PRPF38AP1	ENSG00000107485	ENSG00000225053		33552	52510	rs10508343-A	rs10508343	0	10508343	intergenic_variant	1	NR	8e-06	5.09691001300806		3.81	[1.40-10.40]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	5p13.2	5	36137518	LMBRD2	LMBRD2			ENSG00000164187	NA	NA	rs267759-A	rs267759	0	267759	intron_variant	0	NR	7e-06	5.15490195998574		3.23	[1.52-6.87]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	11q21	11	96266936	MAML2	MAML2			ENSG00000184384	NA	NA	rs7115578-A	rs7115578	0	7115578	intron_variant	0	NR	8e-06	5.09691001300806		1.86	[1.23-2.79]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	11p15.1	11	20540973	intergenic	PRMT3 - HMGB1P40	ENSG00000185238	ENSG00000255291		31635	33213	rs7128311-C	rs7128311	0	7128311	intergenic_variant	1	NR	5e-06	5.30102999566398		13.9	[2.72-71.1]	Affymetrix [476796]	N
2009-02-26	19176441	Yang JJ	2009-01-28	JAMA	www.ncbi.nlm.nih.gov/pubmed/19176441	Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia.	Response to treatment for acute lymphoblastic leukemia	356 European ancestry cases, 53 Black cases, 78 cases	NA	10p12.33	10	17346144	ST8SIA6	ST8SIA6			ENSG00000148488	NA	NA	rs359312-T	rs359312	0	359312	intron_variant	0	NR	9e-08	7.04575749056067		3.91	[1.52-10.10]	Affymetrix [476796]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	2q37.2	2	234706553	ARL4C	LINC01173			ENSG00000280744	NA	NA	rs6736997-A	rs6736997	0	6736997	intron_variant	0	0.33	6e-06	5.22184874961636	(recessive)	1.57	[1.29-1.91]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	7q36.2	7	153928758	DPP6	DPP6			ENSG00000130226	NA	NA	rs6464375-A	rs6464375	0	6464375	intron_variant	0	0.10	4e-07	6.39794000867204	(recessive)	3.73	[2.24-6.21]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	6p25.3	6	1339954	FOXQ1	LINC01394 - AL034346.1	ENSG00000281809	ENSG00000261730		15932	43836	rs9502893-G	rs9502893	0	9502893	intergenic_variant	1	0.35	3e-07	6.52287874528034	(allelic)	1.29	[1.17-1.43]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	8q24.13	8	123753462	FAM91A1	ANXA13 - FAM91A1	ENSG00000104537	ENSG00000176853		16060	14977	rs10088262-A	rs10088262	0	10088262	intergenic_variant	1	0.34	4e-06	5.39794000867204	(dominant)	1.4	[1.21-1.61]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	2q12.1	2	104762499	LOC284998	PANTR1			ENSG00000233639	NA	NA	rs12615966-A	rs12615966	0	12615966	intergenic_variant	0	0.10	7e-06	5.15490195998574	(recessive)	3.15	[1.91-5.21]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	13q22.1	13	73357977	LOC730242	RNY1P8 - AL162376.1	ENSG00000206697	ENSG00000279754		130717	41054	rs1886449-A	rs1886449	0	1886449	intergenic_variant	1	0.38	9e-06	5.04575749056067	(recessive)	1.51	[1.26-1.80]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	13q31.1	13	79725587	NDFIP2	AL136442.1 - LINC01038	ENSG00000285902	ENSG00000229011		58243	78831	rs2039553-A	rs2039553	0	2039553	regulatory_region_variant	1	0.27	7e-06	5.15490195998574	(recessive)	1.73	[1.36-2.19]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	17p11.2	17	18850557	PRPSAP2	PRPSAP2			ENSG00000141127	NA	NA	rs4924935-G	rs4924935	0	4924935	intron_variant	0	0.23	8e-06	5.09691001300806	(dominant)	1.37	[1.19-1.58]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	8p11.22	8	38611785	RNF5P1	RNF5P1 - AC016813.1	ENSG00000253570	ENSG00000254321		10585	87489	rs7832232-A	rs7832232	0	7832232	intergenic_variant	1	0.45	5e-06	5.30102999566398	(recessive)	1.45	[1.24-1.71]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	5p15.33	5	2109787	LOC731559	AC124852.1			ENSG00000248994	NA	NA	rs6879627-G	rs6879627	0	6879627	intron_variant	0	0.52	8e-06	5.09691001300806	(allelic)	1.25	[1.14-1.39]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	12p11.21	12	32283475	BICD1	BICD1			ENSG00000151746	NA	NA	rs708224-A	rs708224	0	708224	intron_variant	0	0.66	3e-07	6.52287874528034	(allelic)	1.32	[1.19-1.47]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	17q11.2	17	32550640	MYO1D	MYO1D			ENSG00000176658	NA	NA	rs225190-G	rs225190	0	225190	intron_variant	0	0.36	6e-06	5.22184874961636	(allelic)	1.26	[1.14-1.39]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	6q26	6	161815043	PARK2	PRKN			ENSG00000185345	NA	NA	rs3016539-A	rs3016539	0	3016539	intron_variant	0	0.87	7e-06	5.15490195998574	(dominant)	1.5	[1.26-1.79]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	2q11.2	2	101305708	RNF149	RNF149			ENSG00000163162	NA	NA	rs6711606-A	rs6711606	0	6711606	intron_variant	0	0.12	4e-06	5.39794000867204	(recessive)	2.81	[1.81-4.37]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	17q22	17	58370936	RNF43	TSPOAP1-AS1, RNF43, AC004687.2			ENSG00000265148, ENSG00000108375, ENSG00000285897	NA	NA	rs2257205-A	rs2257205	0	2257205	missense_variant	0	0.33	8e-06	5.09691001300806	(dominant)	1.38	[1.20-1.59]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	2q22.1	2	136797654	THSD7B	THSD7B			ENSG00000144229	NA	NA	rs1427593-A	rs1427593	0	1427593	intron_variant	0	0.08	7e-06	5.15490195998574	(dominant)	1.49	[1.25-1.77]	Illumina [420236]	N
2010-09-10	20686608	Low SK	2010-07-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/20686608	Genome-wide association study of pancreatic cancer in Japanese population.	Pancreatic cancer	991 Japanese ancestry cases, 5,209 Japanese ancestry controls	NA	13q21.32	13	65907683	LOC387933	LINC01052			ENSG00000234767	NA	NA	rs1585440-C	rs1585440	0	1585440	intron_variant	0	0.71	9e-06	5.04575749056067	(allelic)	1.3	[1.16-1.45]	Illumina [420236]	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	3p12.3	3	78304441	intergenic	AC108752.1 - MRPS17P3	ENSG00000240241	ENSG00000239226		9710	220660	rs9831754-T	rs9831754	0	9831754	intergenic_variant	1	NR	8e-06	5.09691001300806		0.02	[NR] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	6q11.1	6	62450242	intergenic	KHDRBS2 - DHFRP5	ENSG00000112232	ENSG00000216859		164017	10698	rs682238-C	rs682238	0	682238	intergenic_variant	1	NR	3e-06	5.52287874528034		0.03	[NR] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	2p23.3	2	27519736	FNDC4, IFT172, GCKR, C2orf16	GCKR			ENSG00000084734	NA	NA	rs780093-T	rs780093	0	780093	intron_variant	0	NR	7e-06	5.15490195998574		0.02	[NR] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	9p22.3	9	15157979	C9orf52	CLCN3P1 - TTC39B	ENSG00000232000	ENSG00000155158		11578	5643	rs1780159-T	rs1780159	0	1780159	regulatory_region_variant	1	NR	6e-06	5.22184874961636		0.03	[NR] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	3q21.1	3	122274400	CASR, WDR5B, C3orf28, CCDC58, CSTA, KPNA1	CASR			ENSG00000036828	NA	NA	rs17251221-G	rs17251221	0	17251221	intron_variant	0	0.14	2e-22	21.698970004336		0.06	[0.05-0.07] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	17p13.3	17	1730810	PRPF8, MGC14376, SMYD4, SERPINF2, SERPINF1, WDR81	WDR81, WDR81, AC130343.1			ENSG00000276021, ENSG00000167716, ENSG00000262791	NA	NA	rs12150338-T	rs12150338	0	12150338	synonymous_variant	0	NR	7e-07	6.15490195998574		0.05	[NR] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	11p15.4	11	2932493	SLC22A18, PHLDA2, CDKN1C, NAP1L4	PHLDA2 - NAP1L4	ENSG00000181649	ENSG00000273562		3073	11938	rs3847646-T	rs3847646	0	3847646	intergenic_variant	1	NR	5e-06	5.30102999566398		0.03	[NR] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	2q37.1	2	233364596	SAG, DGKD	DGKD, DGKD			ENSG00000280873, ENSG00000077044	NA	NA	rs838705-A	rs838705	0	838705	intron_variant	0	NR	9e-06	5.04575749056067		0.02	[NR] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	6p24.3	6	10163735	intergenic	OFCC1			ENSG00000181355	NA	NA	rs13195786-?	rs13195786	0	13195786	intron_variant	0	NR	7e-06	5.15490195998574		0.03	[NR] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-21	20705733	O'Seaghdha CM	2010-08-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20705733	Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels.	Calcium levels	20,611 European ancestry individuals	NA	20q13.2	20	53733353	intergenic	RNU7-14P - AC005914.1	ENSG00000238468	ENSG00000287886		64595	5375	rs6091737-T	rs6091737	0	6091737	intergenic_variant	1	NR	6e-06	5.22184874961636		0.02	[NR] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-03-01	19198612	Erdmann J	2009-02-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19198612	New susceptibility locus for coronary artery disease on chromosome 3q22.3.	Coronary heart disease	1,222 European ancestry cases, 1,298 European ancestry controls	18,185 European ancestry cases, 20,068 European ancestry controls	3q22.3	3	138403280	MRAS	MRAS			ENSG00000158186	NA	NA	rs9818870-T	rs9818870	0	9818870	3_prime_UTR_variant	0	0.15	7e-13	12.1549019599857		1.15	[1.11-1.19]	Affymetrix [567119]	N
2009-03-01	19198612	Erdmann J	2009-02-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19198612	New susceptibility locus for coronary artery disease on chromosome 3q22.3.	Coronary heart disease	1,222 European ancestry cases, 1,298 European ancestry controls	18,185 European ancestry cases, 20,068 European ancestry controls	12q24.31	12	120997784	C12orf43, HNF1A	HNF1A			ENSG00000135100	NA	NA	rs2259816-T	rs2259816	0	2259816	synonymous_variant	0	0.36	5e-07	6.30102999566398		1.08	[1.05-1.11]	Affymetrix [567119]	N
2012-01-27	22182935	Chen DT	2011-12-20	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22182935	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	Bipolar disorder	5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese ancestry cases, 1,000 Taiwanese ancestry controls	1,115 European ancestry cases, 2,728 European ancestry controls	1p31.1	1	78772330	PTGFR	AC104837.1 - ADGRL4	ENSG00000235400	ENSG00000162618		21671	117434	rs4650608-T	rs4650608	0	4650608	intergenic_variant	1	NR	8e-09	8.09691001300806		NA		Affymetrix, Illumina [748555]	N
2012-01-27	22182935	Chen DT	2011-12-20	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22182935	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	Bipolar disorder	5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese ancestry cases, 1,000 Taiwanese ancestry controls	1,115 European ancestry cases, 2,728 European ancestry controls	2q11.2	2	96739703	LMAN2L	LMAN2L			ENSG00000114988	NA	NA	rs2271893-G	rs2271893	0	2271893	intron_variant	0	NR	2e-10	9.69897000433602		NA		Affymetrix, Illumina [748555]	N
2012-01-27	22182935	Chen DT	2011-12-20	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22182935	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	Bipolar disorder	5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese ancestry cases, 1,000 Taiwanese ancestry controls	1,115 European ancestry cases, 2,728 European ancestry controls	3p21.2	3	52245578	intergenic	AC006252.1 - PPM1M	ENSG00000243224	ENSG00000164088		4481	181	rs7618915-G	rs7618915	0	7618915	regulatory_region_variant	1	NR	3e-10	9.52287874528034		NA		Affymetrix, Illumina [748555]	N
2012-01-27	22182935	Chen DT	2011-12-20	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22182935	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	Bipolar disorder	5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese ancestry cases, 1,000 Taiwanese ancestry controls	1,115 European ancestry cases, 2,728 European ancestry controls	3p22.2	3	36814539	TRANK1	HSPD1P6 - LINC02033	ENSG00000230067	ENSG00000279727		30372	4737	rs9834970-C	rs9834970	0	9834970	regulatory_region_variant	1	NR	1e-12	12		NA		Affymetrix, Illumina [748555]	N
2012-01-27	22182935	Chen DT	2011-12-20	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22182935	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	Bipolar disorder	5,568 European ancestry cases, 7,187 European ancestry controls, 1,000 Taiwanese ancestry cases, 1,000 Taiwanese ancestry controls	1,115 European ancestry cases, 2,728 European ancestry controls	10q21.2	10	60425736	ANK3	ANK3			ENSG00000151150	NA	NA	rs4948418-T	rs4948418	0	4948418	intron_variant	0	NR	4e-10	9.39794000867204		NA		Affymetrix, Illumina [748555]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	1p13.1	1	116558335	CD58	CD58			ENSG00000116815	NA	NA	rs1335532-A	rs1335532	0	1335532	intron_variant	0	0.87	1e-07	7		1.28	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	1p22.1	1	92838046	RPL5, EVI5	DIPK1A, RPL5			ENSG00000154511, ENSG00000122406	NA	NA	rs6604026-G	rs6604026	0	6604026	intron_variant	0	0.28	3e-06	5.52287874528034		1.17	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	12q14.1	12	57768956	CYP27B1, METTL1	METTL1, CYP27B1			ENSG00000037897, ENSG00000111012	NA	NA	rs703842-A	rs703842	0	703842	missense_variant	0	0.67	5e-11	10.301029995664		1.23	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	6p21.32	6	32619077	HLA-DRB1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		29229	9102	rs9271366-G	rs9271366	0	9271366	intergenic_variant	1	0.15	7e-184	183.154901959986		2.78	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	10p15.1	10	6057082	IL2RA	IL2RA			ENSG00000134460	NA	NA	rs2104286-A	rs2104286	0	2104286	intron_variant	0	0.73	7e-06	5.15490195998574		1.16	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	20q13.12	20	46111557	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017		11381	6721	rs6074022-G	rs6074022	0	6074022	TF_binding_site_variant	1	0.25	1e-07	7		1.2	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	16p12.2	16	23055939	NR	AC127459.2 - AC127459.1	ENSG00000261090	ENSG00000260566		29654	5467	rs8049603-T	rs8049603	0	8049603	intergenic_variant	1	0.20	1e-06	6		1.19	[NR]	Illumina [302098]	N
2009-06-30	19525955	Bahlo M	2009-06-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19525955	Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.	Multiple sclerosis	1,618 European ancestry cases, 3,413 European ancestry controls	2,256 European ancestry cases, 2,310 European ancestry controls	8q24.21	8	130080167	ASAP1, DDEF1	ASAP1			ENSG00000153317	NA	NA	rs6984045-C	rs6984045	0	6984045	intron_variant	0	0.02	2e-06	5.69897000433602		1.59	[NR]	Illumina [302098]	N
2010-02-08	20081857	Saxena R	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081857	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.	Two-hour glucose challenge	15,234 individuals	up to 30,620 European ancestry individuals	3q21.1	3	123375604	ADCY5	ADCY5			ENSG00000173175	NA	NA	rs2877716-C	rs2877716	0	2877716	intron_variant	0	NR	7e-16	15.1549019599857		0.09	[0.07-0.11] mmol/L increase	Affymetrix, Illumina [NR]	N
2010-02-08	20081857	Saxena R	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081857	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.	Two-hour glucose challenge	15,234 individuals	up to 30,620 European ancestry individuals	10q25.2	10	113029056	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs12243326-C	rs12243326	0	12243326	intron_variant	0	NR	1e-07	7		0.08	[0.06-0.10] mmol/L increase	Affymetrix, Illumina [NR]	N
2010-02-08	20081857	Saxena R	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081857	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.	Two-hour glucose challenge	15,234 individuals	up to 30,620 European ancestry individuals	15q22.2	15	62040781	VPS13C	VPS13C			ENSG00000129003	NA	NA	rs17271305-G	rs17271305	0	17271305	intron_variant	0	NR	1e-07	7		0.06	[0.04-0.08 mmol/L increase	Affymetrix, Illumina [NR]	N
2010-02-08	20081857	Saxena R	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081857	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.	Two-hour glucose challenge	15,234 individuals	up to 30,620 European ancestry individuals	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-T	rs1260326	0	1260326	missense_variant	0	NR	3e-10	9.52287874528034		0.07	[0.05-0.09] mmol/L increase	Affymetrix, Illumina [NR]	N
2010-02-08	20081857	Saxena R	2010-01-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20081857	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.	Two-hour glucose challenge	15,234 individuals	up to 30,620 European ancestry individuals	19q13.32	19	45679046	GIPR	GIPR			ENSG00000010310	NA	NA	rs10423928-A	rs10423928	0	10423928	intron_variant	0	NR	3e-12	11.5228787452803		0.09	[0.07-0.11] mmol/L increase	Affymetrix, Illumina [NR]	N
2009-07-24	19581569	Treutlein J	2009-07-01	Arch Gen Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19581569	Genome-wide association study of alcohol dependence.	Alcohol dependence	476 European ancestry cases, 1,358 European ancestry controls	1,024 European ancestry cases, 996 European ancestry controls	Xp22.2	X	10263651	intergenic	AC003666.1			ENSG00000227042	NA	NA	rs12388359-T	rs12388359	0	12388359	intron_variant	0	0.11	4e-06	5.39794000867204		1.61	[1.32-2.00]	Illumina [524396]	N
2009-07-24	19581569	Treutlein J	2009-07-01	Arch Gen Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19581569	Genome-wide association study of alcohol dependence.	Alcohol dependence	476 European ancestry cases, 1,358 European ancestry controls	1,024 European ancestry cases, 996 European ancestry controls	2q35	2	216033935	PECR	MREG, PECR			ENSG00000118242, ENSG00000115425	NA	NA	rs7590720-G	rs7590720	0	7590720	intron_variant	0	0.29	1e-08	8		1.35	[1.22-1.49]	Illumina [524396]	N
2009-07-24	19581569	Treutlein J	2009-07-01	Arch Gen Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19581569	Genome-wide association study of alcohol dependence.	Alcohol dependence	476 European ancestry cases, 1,358 European ancestry controls	1,024 European ancestry cases, 996 European ancestry controls	5q15	5	96775667	CAST, ERAP1	ERAP1, CAST			ENSG00000164307, ENSG00000153113	NA	NA	rs13160562-G	rs13160562	0	13160562	3_prime_UTR_variant	0	0.68	7e-06	5.15490195998574		1.27	[1.14-1.41]	Illumina [524396]	N
2009-07-24	19581569	Treutlein J	2009-07-01	Arch Gen Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19581569	Genome-wide association study of alcohol dependence.	Alcohol dependence	476 European ancestry cases, 1,358 European ancestry controls	1,024 European ancestry cases, 996 European ancestry controls	5q32	5	146941260	PPP2R2B	PPP2R2B			ENSG00000156475	NA	NA	rs1864982-A	rs1864982	0	1864982	intron_variant	0	0.13	3e-06	5.52287874528034		1.36	[1.20-1.55]	Illumina [524396]	N
2009-07-24	19581569	Treutlein J	2009-07-01	Arch Gen Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19581569	Genome-wide association study of alcohol dependence.	Alcohol dependence	476 European ancestry cases, 1,358 European ancestry controls	1,024 European ancestry cases, 996 European ancestry controls	6q25.1	6	151836746	ESR1	ESR1			ENSG00000091831	NA	NA	rs6902771-C	rs6902771	0	6902771	intron_variant	0	0.51	8e-06	5.09691001300806		1.24	[1.13-1.36]	Illumina [524396]	N
2009-07-24	19581569	Treutlein J	2009-07-01	Arch Gen Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19581569	Genome-wide association study of alcohol dependence.	Alcohol dependence	476 European ancestry cases, 1,358 European ancestry controls	1,024 European ancestry cases, 996 European ancestry controls	14q24.2	14	70885931	intergenic	AC004825.1 - AC004825.2	ENSG00000258431	ENSG00000274818		26502	20726	rs36563-A	rs36563	0	36563	intergenic_variant	1	0.15	5e-06	5.30102999566398		1.33	[1.18-1.50]	Illumina [524396]	N
2009-03-01	19230858	Schrauwen I	2009-02-18	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19230858	A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosis.	Otosclerosis	302 cases, 302 controls	847 cases, 872 controls	7q22.1	7	103886922	RELN	RELN			ENSG00000189056	NA	NA	rs3914132-?	rs3914132	0	3914132	intron_variant	0	0.23	2e-08	7.69897000433602		1.54	[1.32-1.79]	Illumina [~ 555000]	N
2009-09-04	19648918	Amundadottir L	2009-08-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19648918	Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.	Pancreatic cancer	1,771 European ancestry cases, 1,805 European ancestry controls	2,120 European ancestry cases, 2,127 European ancestry controls	9q34.2	9	133273813	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs505922-C	rs505922	0	505922	intron_variant	0	0.35	5e-08	7.30102999566398		1.2	[1.12-1.28]	Illumina [558542]	N
2009-07-12	19567438	Elliott P	2009-07-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/19567438	Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.	C-reactive protein	17,967 European ancestry and Indian Asian ancestry individuals	13,615 European ancestry and Indian Asian ancestry Individuals	1q21.3	1	154446403	IL6R	IL6R			ENSG00000160712	NA	NA	rs4537545-T	rs4537545	0	4537545	intron_variant	0	NR	2e-14	13.698970004336		11.5	[8.5-14.4] % decrease	Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)	N
2009-07-12	19567438	Elliott P	2009-07-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/19567438	Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.	C-reactive protein	17,967 European ancestry and Indian Asian ancestry individuals	13,615 European ancestry and Indian Asian ancestry Individuals	12q24.31	12	120983004	HNF1A	HNF1A			ENSG00000135100	NA	NA	rs1183910-T	rs1183910	0	1183910	intron_variant	0	NR	1e-30	30		13.8	[10.9-16.6] % decrease	Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)	N
2009-07-12	19567438	Elliott P	2009-07-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/19567438	Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.	C-reactive protein	17,967 European ancestry and Indian Asian ancestry individuals	13,615 European ancestry and Indian Asian ancestry Individuals	1q23.2	1	159728759	CRP	CRP - AL445528.1	ENSG00000132693	ENSG00000235226		14170	30411	rs7553007-A	rs7553007	0	7553007	intergenic_variant	1	NR	8e-44	43.0969100130081		20.7	[18.9-23.4] % decrease	Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)	N
2009-07-12	19567438	Elliott P	2009-07-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/19567438	Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.	C-reactive protein	17,967 European ancestry and Indian Asian ancestry individuals	13,615 European ancestry and Indian Asian ancestry Individuals	1p31.3	1	65624099	LEPR	LEPR			ENSG00000116678	NA	NA	rs6700896-T	rs6700896	0	6700896	intron_variant	0	NR	3e-14	13.5228787452803		14.8	[12.0-17.6] % decrease	Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)	N
2009-07-12	19567438	Elliott P	2009-07-01	JAMA	www.ncbi.nlm.nih.gov/pubmed/19567438	Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.	C-reactive protein	17,967 European ancestry and Indian Asian ancestry individuals	13,615 European ancestry and Indian Asian ancestry Individuals	19q13.32	19	44919689	APOE, APOCII, APOC1	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-G	rs4420638	0	4420638	regulatory_region_variant	1	NR	5e-27	26.301029995664		21.8	[18.1-25.3] % decrease	Affymetrix, Illumina, Perlegen [~ 1400000] (imputed)	N
2012-03-17	22367966	Lin X	2012-02-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22367966	Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.	Vitamin B12 levels	1,999 Han Chinese ancestry individuals	1,496 Chinese ancestry individuals	19q13.33	19	48703374	FUT2	FUT2			ENSG00000176920	NA	NA	rs1047781-?	rs1047781	0	1047781	missense_variant	0	NR	4e-36	35.397940008672		70.21	[59.37-81.05] pg/ml increase	Illumina [1940245] (imputed)	N
2012-03-17	22367966	Lin X	2012-02-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22367966	Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.	Vitamin B12 levels	1,999 Han Chinese ancestry individuals	1,496 Chinese ancestry individuals	5q32	5	145659268	intergenic	PRELID2			ENSG00000186314	NA	NA	rs10515552-?	rs10515552	0	10515552	intron_variant	0	NR	4e-08	7.39794000867204		43.93	[28.29-59.57] pg/ml increase	Illumina [1940245] (imputed)	N
2012-03-17	22367966	Lin X	2012-02-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22367966	Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.	Vitamin B12 levels	1,999 Han Chinese ancestry individuals	1,496 Chinese ancestry individuals	9p21.1	9	32914591	intergenic	APTX			ENSG00000137074	NA	NA	rs12377462-?	rs12377462	0	12377462	intron_variant	0	NR	2e-06	5.69897000433602		28.53	[16.79-40.27] pg/ml increase	Illumina [1940245] (imputed)	N
2012-03-17	22367966	Lin X	2012-02-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22367966	Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.	Vitamin B12 levels	1,999 Han Chinese ancestry individuals	1,496 Chinese ancestry individuals	11q12.1	11	60069719	MS4A3	MS4A3			ENSG00000149516	NA	NA	rs2298585-?	rs2298585	0	2298585	intron_variant	0	NR	3e-15	14.5228787452803		71.8	[54.08-89.52] pg/ml increase	Illumina [1940245] (imputed)	N
2012-03-17	22367966	Lin X	2012-02-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22367966	Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.	Vitamin B12 levels	1,999 Han Chinese ancestry individuals	1,496 Chinese ancestry individuals	13q32.3	13	99866380	CLYBL	CLYBL, AL137139.2			ENSG00000125246, ENSG00000286757	NA	NA	rs41281112-?	rs41281112	0	41281112	stop_gained	0	NR	9e-10	9.04575749056067		83.6	[56.90-110.30] pg/ml decrease	Illumina [1940245] (imputed)	N
2012-03-17	22367966	Lin X	2012-02-24	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22367966	Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.	Vitamin B12 levels	1,999 Han Chinese ancestry individuals	1,496 Chinese ancestry individuals	19p13.3	19	5839735	FUT6	FUT6 - FUT3	ENSG00000156413	ENSG00000171124		4	3153	rs3760776-?	rs3760776	0	3760776	TF_binding_site_variant	1	NR	4e-13	12.397940008672		49.78	[36.41-63.15] pg/ml increase	Illumina [1940245] (imputed)	N
2009-06-14	19483682	Kanetsky PA	2009-05-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19483682	Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.	Testicular cancer	277 European ancestry cases, 919 European ancestry controls	371 European ancestry  cases with their 408 parents, 860 European ancestry controls	12q21.32	12	88560182	KITLG	KITLG			ENSG00000049130	NA	NA	rs4474514-A	rs4474514	0	4474514	intron_variant	0	NR	6e-15	14.2218487496164		3.07	[2.29-4.13]	Affymetrix [611254]	N
2009-02-25	19165155	Ling H	2009-01-22	Obesity (Silver Spring)	www.ncbi.nlm.nih.gov/pubmed/19165155	Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.	Adiponectin levels	997 European ancestry cases, 989 European ancestry controls	NA	3q27.3	3	186855916	ADIPOQ	ADIPOQ-AS1, ADIPOQ			ENSG00000226482, ENSG00000181092	NA	NA	rs6773957-A	rs6773957	0	6773957	3_prime_UTR_variant	0	0.37	5e-08	7.30102999566398		NA		Affymetrix [398625]	N
2009-02-25	19165155	Ling H	2009-01-22	Obesity (Silver Spring)	www.ncbi.nlm.nih.gov/pubmed/19165155	Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.	Adiponectin levels	997 European ancestry cases, 989 European ancestry controls	NA	5q35.2	5	173507895	intergenic	AC008632.1 - AC008663.1	ENSG00000253141	ENSG00000253768		23311	54583	rs7722022-?	rs7722022	0	7722022	intergenic_variant	1	NR	9e-06	5.04575749056067		NA		Affymetrix [398625]	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	10p15.1	10	6430929	PRKCQ	PRKCQ			ENSG00000065675	NA	NA	rs11258747-?	rs11258747	0	11258747	missense_variant	0	NR	1e-07	7		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	12q13.2	12	56088396	ERBB3	ERBB3			ENSG00000065361	NA	NA	rs2292239-?	rs2292239	0	2292239	intron_variant	0	NR	2e-25	24.698970004336		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	12q24.12	12	111446804	SH2B3	ATXN2, SH2B3			ENSG00000204842, ENSG00000111252	NA	NA	rs3184504-?	rs3184504	0	3184504	missense_variant	0	NR	3e-27	26.5228787452803		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	15q25.1	15	78943104	CTSH	CTSH			ENSG00000103811	NA	NA	rs3825932-?	rs3825932	0	3825932	intron_variant	0	NR	8e-08	7.09691001300806		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	18p11.21	18	12809341	PTPN2	PTPN2			ENSG00000175354	NA	NA	rs1893217-?	rs1893217	0	1893217	intron_variant	0	NR	4e-15	14.397940008672		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	21q22.3	21	42416077	UBASH3A	UBASH3A			ENSG00000160185	NA	NA	rs11203203-?	rs11203203	0	11203203	intron_variant	0	NR	2e-09	8.69897000433602		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	1q32.1	1	206766559	IL10	Y_RNA - IL10	ENSG00000265852	ENSG00000136634		18467	1043	rs3024505-?	rs3024505	0	3024505	intergenic_variant	1	0.83	2e-09	8.69897000433602		1.19	[1.10-1.30]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	6q22.32	6	126377573	C6orf173	AL356534.1			ENSG00000286215	NA	NA	rs9388489-G	rs9388489	0	9388489	intron_variant	0	0.45	4e-13	12.397940008672		1.17	[1.10-1.24]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	7p12.1	7	50959497	COBL	AC004830.2			ENSG00000228204	NA	NA	rs4948088-?	rs4948088	0	4948088	intron_variant	0	0.95	4e-08	7.39794000867204		1.3	[1.11-1.49]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	10q23.31	10	88263276	C10orf59	AL353149.1 - RNLS	ENSG00000275015	ENSG00000184719		3904	10588	rs10509540-?	rs10509540	0	10509540	intergenic_variant	1	0.71	1e-28	28		1.33	[1.25-1.43]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	12p13.31	12	9757568	CD69	CD69			ENSG00000110848	NA	NA	rs4763879-A	rs4763879	0	4763879	intron_variant	0	0.37	2e-11	10.698970004336		1.09	[1.02-1.16]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	14q32.2	14	98032614	intergenic	LINC01550 - AL163932.1	ENSG00000246223	ENSG00000259097		54490	35547	rs4900384-G	rs4900384	0	4900384	intergenic_variant	1	0.29	4e-09	8.39794000867204		1.09	[1.02-1.16]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	16q23.1	16	75213347	intergenic	CTRB2 - CTRB1	ENSG00000168928	ENSG00000168925		6186	5641	rs7202877-G	rs7202877	0	7202877	intergenic_variant	1	0.10	3e-15	14.5228787452803		1.28	[1.17-1.41]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	20p13	20	1629905	intergenic	SIRPG			ENSG00000089012	NA	NA	rs2281808-?	rs2281808	0	2281808	intron_variant	0	0.64	1e-11	11		1.11	[1.05-1.19]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	22q12.2	22	30185733	intergenic	AC002378.1			ENSG00000225676	NA	NA	rs5753037-T	rs5753037	0	5753037	intron_variant	0	0.39	3e-16	15.5228787452803		1.1	[1.04-1.17]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	1p31.3	1	63643100	PGM1	PGM1			ENSG00000079739	NA	NA	rs2269241-G	rs2269241	0	2269241	intron_variant	0	0.19	4e-07	6.39794000867204		1.1	[1.02-1.18]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	2p24.3	2	12500615	intergenic	MIR3681HG			ENSG00000224184	NA	NA	rs1534422-G	rs1534422	0	1534422	intron_variant	0	0.46	2e-06	5.69897000433602		1.08	[1.02-1.15]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	6p21.32	6	32440750	MHC	HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA, HLA-DRA			ENSG00000228987, ENSG00000206308, ENSG00000230726, ENSG00000204287, ENSG00000226260, ENSG00000227993, ENSG00000234794	NA	NA	rs9268645-?	rs9268645	0	9268645	intron_variant	0	NR	1e-100	100		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	1p13.2	1	113834946	PTPN22	PTPN22, AL137856.1			ENSG00000134242, ENSG00000231128	NA	NA	rs2476601-?	rs2476601	0	2476601	missense_variant	0	NR	9e-85	84.0457574905607		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	2q24.2	2	162267541	IFIH1	IFIH1			ENSG00000115267	NA	NA	rs1990760-?	rs1990760	0	1990760	missense_variant	0	NR	7e-09	8.15490195998574		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	4q27	4	122211337	IL2	KIAA1109			ENSG00000138688	NA	NA	rs4505848-?	rs4505848	0	4505848	intron_variant	0	NR	5e-13	12.301029995664		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	17q21.1	17	39909987	ORMDL3	GSDMB			ENSG00000073605	NA	NA	rs2290400-?	rs2290400	0	2290400	intron_variant	0	0.50	6e-13	12.2218487496164		1.15	[1.08-1.22]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	2q33.2	2	203874196	CTLA4	CTLA4 - ICOS	ENSG00000163599	ENSG00000163600		231	62552	rs3087243-?	rs3087243	0	3087243	intergenic_variant	1	NR	1e-15	15		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	7p15.2	7	26852046	intergenic	SKAP2			ENSG00000005020	NA	NA	rs7804356-?	rs7804356	0	7804356	intron_variant	0	0.76	5e-09	8.30102999566398		1.14	[1.06-1.22]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	17p13.1	17	7730374	intergenic	DNAH2			ENSG00000183914	NA	NA	rs16956936-?	rs16956936	0	16956936	intron_variant	0	0.86	5e-07	6.30102999566398		1.09	[1.00-1.19]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	19q13.32	19	46705224	intergenic	PRKD2			ENSG00000105287	NA	NA	rs425105-?	rs425105	0	425105	intron_variant	0	0.84	3e-11	10.5228787452803		1.16	[1.08-1.27]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	17q21.2	17	40614034	intergenic	AC004585.2 - SMARCE1	ENSG00000279775	ENSG00000073584		15449	10928	rs7221109-?	rs7221109	0	7221109	intergenic_variant	1	0.65	1e-09	9		1.05	[0.99-1.12]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	Xq28	X	154717327	intergenic	GAB3			ENSG00000160219	NA	NA	rs2664170-G	rs2664170	0	2664170	intron_variant	0	0.32	8e-09	8.09691001300806		1.16	[1.07-1.24]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	16p12.3	16	20331250	intergenic	GP2 - UMOD	ENSG00000169347	ENSG00000169344		3442	1802	rs12444268-A	rs12444268	0	12444268	intergenic_variant	1	0.30	2e-07	6.69897000433602		1.1	[1.03-1.17]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	6q15	6	90248512	BACH2	BACH2			ENSG00000112182	NA	NA	rs11755527-?	rs11755527	0	11755527	intron_variant	0	NR	5e-08	7.30102999566398		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	10p15.1	10	6081532	IL2RA	RPL32P23 - RBM17	ENSG00000214015	ENSG00000134453		9614	7502	rs12251307-?	rs12251307	0	12251307	intergenic_variant	1	NR	1e-13	13		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	11p15.5	11	2191936	INS	MIR4686 - ASCL2	ENSG00000265258	ENSG00000183734		18798	76559	rs7111341-?	rs7111341	0	7111341	regulatory_region_variant	1	NR	4e-48	47.397940008672		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	16p13.13	16	11086016	CLEC16A	CLEC16A			ENSG00000038532	NA	NA	rs12708716-?	rs12708716	0	12708716	intron_variant	0	NR	2e-16	15.698970004336		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	22q12.3	22	37195278	C1QTNF6	C1QTNF6			ENSG00000133466	NA	NA	rs229541-?	rs229541	0	229541	intron_variant	0	NR	2e-07	6.69897000433602		NA		Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	4p15.2	4	26083889	intergenic	LINC02357			ENSG00000283314	NA	NA	rs10517086-A	rs10517086	0	10517086	intron_variant	0	0.30	5e-10	9.30102999566398		1.09	[1.02-1.17]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	9p24.2	9	4291747	GLIS3	GLIS3			ENSG00000107249	NA	NA	rs7020673-?	rs7020673	0	7020673	intron_variant	0	0.50	5e-12	11.301029995664		1.14	[1.08-1.20]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	14q24.1	14	68796882	intergenic	ZFP36L1 - MAGOH3P	ENSG00000185650	ENSG00000270975		629	64880	rs1465788-?	rs1465788	0	1465788	regulatory_region_variant	1	0.71	2e-12	11.698970004336		1.16	[1.10-1.25]	Affymetrix, Illumina [841622] (imputed)	N
2009-06-01	19430480	Barrett JC	2009-05-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19430480	Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.	Type 1 diabetes	7,514 European ancestry cases, 9,045 European ancestry controls	4,267 European ancestry cases, 4,670 European ancestry controls, 4,342 European ancestry trios from 2,319 families	16p11.2	16	28528527	IL27	IL27 - NUPR1	ENSG00000197272	ENSG00000176046		16476	4181	rs4788084-G	rs4788084	0	4788084	regulatory_region_variant	1	0.42	3e-13	12.5228787452803		1.09	[1.02-1.16]	Affymetrix, Illumina [841622] (imputed)	N
2011-01-15	21149283	Oexle K	2010-12-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21149283	Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.	Iron status biomarkers	Up to 6,616 individuals	NA	11q23.3	11	117220893	PCSK7	PCSK7			ENSG00000160613	NA	NA	rs236918-C	rs236918	0	236918	non_coding_transcript_exon_variant	0	NR	1e-27	27	(sTfR)	0.038	[0.03-0.05] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-01-15	21149283	Oexle K	2010-12-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21149283	Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.	Iron status biomarkers	Up to 6,616 individuals	NA	11q23.3	11	116851325	APOA	SIK3, APOA1-AS			ENSG00000160584, ENSG00000235910	NA	NA	rs10047462-T	rs10047462	0	10047462	intron_variant	0	NR	4e-25	24.397940008672	(sTfR)	0.041	[0.03-0.05] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-01-15	21149283	Oexle K	2010-12-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21149283	Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.	Iron status biomarkers	Up to 6,616 individuals	NA	6p22.2	6	25842723	HFE	SLC17A3			ENSG00000124564	NA	NA	rs1408272-T	rs1408272	0	1408272	intron_variant	0	NR	9e-09	8.04575749056067	(sTfR)	0.038	[0.03-0.05] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-01-15	21149283	Oexle K	2010-12-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21149283	Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.	Iron status biomarkers	Up to 6,616 individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-A	rs855791	0	855791	missense_variant	0	NR	2e-15	14.698970004336	(sTfR)	0.019	[0.015-0.023] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-01-15	21149283	Oexle K	2010-12-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21149283	Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.	Iron status biomarkers	Up to 6,616 individuals	NA	6p22.2	6	25821542	HFE	SLC17A1			ENSG00000124568	NA	NA	rs17342717-T	rs17342717	0	17342717	intron_variant	0	NR	9e-10	9.04575749056067	(ferritin)	0.087	[0.06-0.12] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639878	Singer JB	2010-07-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20639878	A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.	Lumiracoxib-related liver injury	31 European ancestry cases, 3 Hispanic cases, 1 case, 176 European, Hispanic and other ancestry controls	79 European ancestry cases, 16 Hispanic ancestry cases, 1 case, 405 European, Hispanic and other ancestry controls	6p21.32	6	32338202	HLA-DRB1	TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1-AS1			ENSG00000234280, ENSG00000232106, ENSG00000206245, ENSG00000204296, ENSG00000206310, ENSG00000226892, ENSG00000237881, ENSG00000236672, ENSG00000225914	NA	NA	rs3129900-?	rs3129900	0	3129900	intron_variant	0	0.105	7e-25	24.1549019599857		7.5	[5.0-11.3]	Affymetrix [682386]	N
2010-02-10	20096396	Kung AW	2010-01-20	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/20096396	Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.	Bone mineral density	785 Han Chinese ancestry extreme high and low BMD female individuals	264 Han Chinese ancestry High BMD individuals, 456 Han Chinese ancestry Low BMD individuals, 3,465 Han Chinese ancestry individuals, 13,913 European ancestry individuals	20p12.2	20	10658895	JAG1	JAG1			ENSG00000101384	NA	NA	rs2273061-A	rs2273061	0	2273061	intron_variant	0	0.31	5e-08	7.30102999566398	(lumbar spine)	0.07	[NR] s.d. increase	Illumina [488853]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	1p36.12	1	22371954	intergenic	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		5472	56884	rs7524102-A	rs7524102	0	7524102	intergenic_variant	1	0.83	3e-07	6.52287874528034		1.1	[1.00-1.21]	Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	1q32.1	1	206770623	IL10	IL10			ENSG00000136634	NA	NA	rs3024493-?	rs3024493	0	3024493	intron_variant	0	NR	8e-08	7.09691001300806		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	16q22.1	16	68557327	CDH1	ZFP90			ENSG00000184939	NA	NA	rs1728785-G	rs1728785	0	1728785	intron_variant	0	0.76	3e-08	7.52287874528034		1.17	[1.07-1.27]	Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	7q31.1	7	107854989	LAMB1	PIGCP2 - DLD	ENSG00000229626	ENSG00000091140		45421	36173	rs886774-G	rs886774	0	886774	regulatory_region_variant	1	0.41	3e-08	7.52287874528034		1.11	[1.03-1.19]	Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	9q34.3	9	136374886	CARD9	CARD9 - SNAPC4	ENSG00000187796	ENSG00000165684		1205	691	rs10781500-?	rs10781500	0	10781500	intergenic_variant	1	NR	7e-06	5.15490195998574		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	20q13.12	20	44436388	HNF4A	LINC01620			ENSG00000168746	NA	NA	rs6017342-C	rs6017342	0	6017342	non_coding_transcript_exon_variant	0	0.52	9e-17	16.0457574905607		1.17	[1.09-1.26]	Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	13q14.11	13	39931373	intergenic	SNORD116 - LINC00598	ENSG00000212553	ENSG00000215483		74146	147733	rs9548988-T	rs9548988	0	9548988	regulatory_region_variant	1	0.46	3e-07	6.52287874528034		1.1	[1.03-1.19]	Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	1p31.3	1	67240275	IL23R	IL23R			ENSG00000162594	NA	NA	rs11209026-?	rs11209026	0	11209026	missense_variant	0	NR	3e-10	9.52287874528034		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	1p36.13	1	19845367	OTUD3, PLA2G2E	AL391883.1 - OTUD3	ENSG00000235434	ENSG00000169914		25865	37028	rs6426833-?	rs6426833	0	6426833	TF_binding_site_variant	1	NR	2e-11	10.698970004336		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	6p21.32	6	32463370	MHC	HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9, HLA-DRB9			ENSG00000234164, ENSG00000232705, ENSG00000228260, ENSG00000227526, ENSG00000196301, ENSG00000227384, ENSG00000237591, ENSG00000226035	NA	NA	rs9268877-?	rs9268877	0	9268877	intron_variant	0	NR	4e-23	22.397940008672		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	1q32.1	1	200908434	KIF21B	INAVA			ENSG00000163362	NA	NA	rs7554511-?	rs7554511	0	7554511	intron_variant	0	NR	1e-06	6		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	3p21.31	3	49664550	MST1	BSN			ENSG00000164061	NA	NA	rs9858542-?	rs9858542	0	9858542	synonymous_variant	0	NR	7e-09	8.15490195998574		NA		Affymetrix [NR]	N
2009-12-11	19915572	Barrett JC	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915572	Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.	Ulcerative colitis	2,361 European ancestry cases, 5,417 European ancestry controls	2,321 European ancestry cases, 4,818 European ancestry controls	10q24.2	10	99530544	NKX2, NKX3	LINC01475			ENSG00000257582	NA	NA	rs6584283-?	rs6584283	0	6584283	intron_variant	0	NR	2e-07	6.69897000433602		NA		Affymetrix [NR]	N
2009-12-10	19915574	Imielinski M	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915574	Common variants at five new loci associated with early-onset inflammatory bowel disease.	Inflammatory bowel disease (early onset)	2,413 European ancestry cases, 6,158 European ancestry controls	1,013 European ancestry cases, 5,805 European ancestry controls	22q12.2	22	30133642	LIF, HORMAD2, MTMR3	HORMAD2			ENSG00000176635	NA	NA	rs2412973-?	rs2412973	0	2412973	intron_variant	0	0.46	2e-09	8.69897000433602		1.15	[1.01-1.31]	Illumina [~ 500000]	N
2009-12-10	19915574	Imielinski M	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915574	Common variants at five new loci associated with early-onset inflammatory bowel disease.	Inflammatory bowel disease (early onset)	2,413 European ancestry cases, 6,158 European ancestry controls	1,013 European ancestry cases, 5,805 European ancestry controls	16p11.2	16	28826194	CCDC101, CLN3, SULT1A1, SULT1A2, NUPR1, IL27, EIF3C	ATXN2L			ENSG00000168488	NA	NA	rs8049439-G	rs8049439	0	8049439	intron_variant	0	0.37	2e-09	8.69897000433602		1.14	[1.00-1.30]	Illumina [~ 500000]	N
2009-12-10	19915574	Imielinski M	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915574	Common variants at five new loci associated with early-onset inflammatory bowel disease.	Inflammatory bowel disease (early onset)	2,413 European ancestry cases, 6,158 European ancestry controls	1,013 European ancestry cases, 5,805 European ancestry controls	19q13.11	19	33259408	intergenic	SLC7A10 - AC008738.6	ENSG00000130876	ENSG00000270212		33558	24570	rs10500264-?	rs10500264	0	10500264	intergenic_variant	1	0.18	4e-10	9.39794000867204		1.21	[1.11-1.31]	Illumina [~ 500000]	N
2009-12-10	19915574	Imielinski M	2009-11-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19915574	Common variants at five new loci associated with early-onset inflammatory bowel disease.	Inflammatory bowel disease (early onset)	2,413 European ancestry cases, 6,158 European ancestry controls	1,013 European ancestry cases, 5,805 European ancestry controls	10q22.3	10	79300560	ZMIZ1	ZMIZ1			ENSG00000108175	NA	NA	rs1250550-?	rs1250550	0	1250550	intron_variant	0	0.68	6e-09	8.22184874961636		1.16	[1.09-1.25]	Illumina [~ 500000]	N
2013-04-23	23350875	Fernandez-Rozadilla C	2013-01-26	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/23350875	A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.	Colorectal cancer	882 European ancestry cases, 473 European ancestry controls	1,436 European ancestry cases, 1,780 European ancestry controls	3p21.31	3	47347457	NR	AC104447.1			ENSG00000280173	NA	NA	rs8180040-?	rs8180040	0	8180040	non_coding_transcript_exon_variant	0	NR	2e-06	5.69897000433602		1.28	[1.15-1.41]	Affymetrix [674718]	N
2013-04-23	23350875	Fernandez-Rozadilla C	2013-01-26	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/23350875	A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.	Colorectal cancer	882 European ancestry cases, 473 European ancestry controls	1,436 European ancestry cases, 1,780 European ancestry controls	8p12	8	29486945	NR	AC084262.2 - AC084026.2	ENSG00000285601	ENSG00000253632		126723	40367	rs12548021-?	rs12548021	0	12548021	intergenic_variant	1	NR	3e-06	5.52287874528034		1.28	[1.155-1.418]	Affymetrix [674718]	N
2013-04-23	23350875	Fernandez-Rozadilla C	2013-01-26	BMC Genomics	www.ncbi.nlm.nih.gov/pubmed/23350875	A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12.	Colorectal cancer	882 European ancestry cases, 473 European ancestry controls	1,436 European ancestry cases, 1,780 European ancestry controls	8q22.1	8	95583508	NR	C8orf37-AS1			ENSG00000253773	NA	NA	rs3104964-?	rs3104964	0	3104964	intron_variant	0	NR	4e-06	5.39794000867204		1.265	[1.144-1.398]	Affymetrix [674718]	N
2011-01-04	21048783	Kamada F	2010-11-04	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/21048783	A genome-wide association study identifies RNF213 as the first Moyamoya disease gene.	Moyamoya disease	72 Japanese ancestry cases, 45 Japanese ancestry controls	63 Japanese ancestry cases, 45 Japanese ancestry controls	17q25.3	17	80374694	RNF213	RNF213, RNF213-AS1			ENSG00000173821, ENSG00000263069	NA	NA	rs6565681-A	rs6565681	0	6565681	3_prime_UTR_variant	0	0.37	2e-08	7.69897000433602		4.82	[2.73-8.49]	Illumina [785720]	N
2010-02-28	20101243	Petersen GM	2010-01-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20101243	A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.	Pancreatic cancer	3,851 European, Chinese and other ancestry cases, 3,934 European, Chinese and other ancestry controls	NA	13q22.1	13	73342491	KLF12, KLF5	RNY1P8 - AL162376.1	ENSG00000206697	ENSG00000279754		115231	56540	rs9543325-C	rs9543325	0	9543325	regulatory_region_variant	1	0.37	3e-11	10.5228787452803		1.26	[1.18-1.35]	Illumina [551766]	N
2010-02-28	20101243	Petersen GM	2010-01-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20101243	A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.	Pancreatic cancer	3,851 European, Chinese and other ancestry cases, 3,934 European, Chinese and other ancestry controls	NA	1q32.1	1	200038304	NR5A2	NR5A2			ENSG00000116833	NA	NA	rs3790844-T	rs3790844	0	3790844	intron_variant	0	0.76	2e-10	9.69897000433602		1.3	[1.19-1.41]	Illumina [551766]	N
2010-02-28	20101243	Petersen GM	2010-01-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20101243	A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.	Pancreatic cancer	3,851 European, Chinese and other ancestry cases, 3,934 European, Chinese and other ancestry controls	NA	5p15.33	5	1321972	CLPTM1L	CLPTM1L			ENSG00000049656	NA	NA	rs401681-T	rs401681	0	401681	intron_variant	0	0.45	7e-07	6.15490195998574		1.19	[1.11-1.27]	Illumina [551766]	N
2009-02-28	19198613	Gudmundsson J	2009-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19198613	Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.	Thyroid cancer	192 European ancestry cases, 37,196 European ancestry controls	432 European ancestry cases, 1,727 European ancestry controls	9q22.33	9	97793827	FOXE1	PTCSC2			ENSG00000236130	NA	NA	rs965513-A	rs965513	0	965513	intron_variant	0	0.34	2e-27	26.698970004336		1.75	[1.59-1.94]	Illumina [304083]	N
2009-02-28	19198613	Gudmundsson J	2009-02-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19198613	Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.	Thyroid cancer	192 European ancestry cases, 37,196 European ancestry controls	432 European ancestry cases, 1,727 European ancestry controls	14q13.3	14	36180040	NKX2-1	PTCSC3 - AL162511.1	ENSG00000259104	ENSG00000258844		3572	33160	rs944289-T	rs944289	0	944289	intergenic_variant	1	0.57	2e-09	8.69897000433602		1.37	[1.24-1.52]	Illumina [304083]	N
2010-10-05	20833655	Cha PC	2010-09-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20833655	Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.	Warfarin maintenance dose	807 Japanese ancestry low dose individuals, 701 Japanese ancestry high dose individuals	444 Japanese ancestry individuals	13q21.1	13	56198562	NR	AL138997.1 - SPATA2P1	ENSG00000286709	ENSG00000228319		144165	15811	rs1512651-?	rs1512651	0	1512651	intergenic_variant	1	NR	6e-06	5.22184874961636		NA		Illumina [485227]	N
2010-10-05	20833655	Cha PC	2010-09-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20833655	Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.	Warfarin maintenance dose	807 Japanese ancestry low dose individuals, 701 Japanese ancestry high dose individuals	444 Japanese ancestry individuals	19p13.12	19	15879621	CYP4F2	CYP4F2			ENSG00000186115	NA	NA	rs2108622-T	rs2108622	0	2108622	missense_variant	0	NR	3e-08	7.52287874528034		NA		Illumina [485227]	N
2010-10-05	20833655	Cha PC	2010-09-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20833655	Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.	Warfarin maintenance dose	807 Japanese ancestry low dose individuals, 701 Japanese ancestry high dose individuals	444 Japanese ancestry individuals	7q22.3	7	106030821	NR	CDHR3			ENSG00000128536	NA	NA	rs10270308-?	rs10270308	0	10270308	synonymous_variant	0	NR	6e-06	5.22184874961636		NA		Illumina [485227]	N
2010-10-05	20833655	Cha PC	2010-09-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20833655	Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.	Warfarin maintenance dose	807 Japanese ancestry low dose individuals, 701 Japanese ancestry high dose individuals	444 Japanese ancestry individuals	16p11.2	16	31096368	VKORC1	VKORC1 - BCKDK	ENSG00000167397	ENSG00000103507		388	9739	rs9923231-?	rs9923231	0	9923231	regulatory_region_variant	1	NR	9e-31	30.0457574905607		NA		Illumina [485227]	N
2010-10-05	20833655	Cha PC	2010-09-10	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20833655	Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese.	Warfarin maintenance dose	807 Japanese ancestry low dose individuals, 701 Japanese ancestry high dose individuals	444 Japanese ancestry individuals	10q23.33	10	94974582	CYP2C9	CYP2C9			ENSG00000138109	NA	NA	rs10509680-?	rs10509680	0	10509680	intron_variant	0	NR	4e-07	6.39794000867204		NA		Illumina [485227]	N
2009-12-03	19890347	Birlea SA	2009-11-05	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19890347	Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.	Vitiligo	32 Romanian founder cases, 44 European ancestry controls	NA	2p16.3	2	47617366	KCNK12	MSH2			ENSG00000095002	NA	NA	rs6544997-?	rs6544997	0	6544997	intron_variant	0	0.47	7e-06	5.15490195998574		NA		Illumina [297342]	N
2009-12-03	19890347	Birlea SA	2009-11-05	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19890347	Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.	Vitiligo	32 Romanian founder cases, 44 European ancestry controls	NA	6q27	6	168540944	SMOC2	SMOC2			ENSG00000112562	NA	NA	rs13208776-?	rs13208776	0	13208776	intron_variant	0	0.38	9e-08	7.04575749056067		NA		Illumina [297342]	N
2009-12-03	19890347	Birlea SA	2009-11-05	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19890347	Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.	Vitiligo	32 Romanian founder cases, 44 European ancestry controls	NA	18q21.31	18	57787145	ATP8B1	ATP8B1			ENSG00000081923	NA	NA	rs10503019-?	rs10503019	0	10503019	intron_variant	0	0.28	3e-06	5.52287874528034		NA		Illumina [297342]	N
2009-12-03	19890347	Birlea SA	2009-11-05	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/19890347	Genome-wide association study of generalized vitiligo in an isolated European founder population identifies SMOC2, in close proximity to IDDM8.	Vitiligo	32 Romanian founder cases, 44 European ancestry controls	NA	21q22.11	21	32008727	HUNK	HUNK			ENSG00000142149	NA	NA	rs2833607-?	rs2833607	0	2833607	intron_variant	0	0.26	2e-06	5.69897000433602		NA		Illumina [297342]	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	3q25.31	3	156679960	TIPARP	TIPARP			ENSG00000163659	NA	NA	rs2665390-C	rs2665390	0	2665390	intron_variant	0	NR	3e-07	6.52287874528034		1.19	[1.11-1.27]	Illumina [2056878] (imputed)	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	1p36.12	1	22164231	NR	AL445253.1 - MIR4418	ENSG00000285873	ENSG00000266564		6830	102008	rs7521902-?	rs7521902	0	7521902	intergenic_variant	1	NR	5e-06	5.30102999566398		1.12	[1.07-1.18]	Illumina [2056878] (imputed)	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	11p14.3	11	25186158	NR	AC087373.1 - RPL36AP40	ENSG00000255368	ENSG00000240298		45135	402317	rs12794435-?	rs12794435	0	12794435	intergenic_variant	1	NR	5e-06	5.30102999566398		1.16	[1.09-1.23]	Illumina [2056878] (imputed)	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	2q31.1	2	176177905	HOXD1, HOXD3	HAGLR, HAGLROS			ENSG00000224189, ENSG00000226363	NA	NA	rs2072590-T	rs2072590	0	2072590	non_coding_transcript_exon_variant	0	NR	5e-14	13.301029995664		1.16	[1.12-1.21]	Illumina [2056878] (imputed)	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	8q24.21	8	128531703	MYC, THEM75	LINC00824			ENSG00000254275	NA	NA	rs10088218-G	rs10088218	0	10088218	intron_variant	0	NR	3e-09	8.52287874528034		1.19	[1.12-1.25]	Illumina [2056878] (imputed)	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	17q21.32	17	48334138	SKAP1	SKAP1			ENSG00000141293	NA	NA	rs9303542-G	rs9303542	0	9303542	intron_variant	0	NR	1e-06	6		1.11	[1.06-1.16]	Illumina [2056878] (imputed)	N
2010-10-12	20852632	Goode EL	2010-09-19	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20852632	A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.	Ovarian cancer	1,768 European ancestry cases, 2,354 European ancestry controls	8,709 European ancestry cases, 51,764 European ancestry controls	17q21.32	17	48279758	NR	SKAP1			ENSG00000141293	NA	NA	rs2084881-?	rs2084881	0	2084881	intron_variant	0	NR	2e-06	5.69897000433602		1.12	[1.07-1.18]	Illumina [2056878] (imputed)	N
2010-10-14	20885792	Naj AC	2010-09-23	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20885792	Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.	Alzheimer's disease (late onset)	931 cases, 1,104 controls	1,338 cases, 2,003 controls	2q13	2	109018801	intergenic	EDAR - Metazoa_SRP	ENSG00000135960	ENSG00000278569		29429	105556	rs4676049-A	rs4676049	0	4676049	intergenic_variant	1	0.08	4e-08	7.39794000867204		1.76	[1.44-2.15]	Illumina [483399]	N
2010-10-14	20885792	Naj AC	2010-09-23	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20885792	Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.	Alzheimer's disease (late onset)	931 cases, 1,104 controls	1,338 cases, 2,003 controls	19q13.32	19	44892362	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-G	rs2075650	0	2075650	intron_variant	0	0.20	5e-36	35.301029995664		2.94	[2.48-3.47]	Illumina [483399]	N
2010-10-14	20885792	Naj AC	2010-09-23	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20885792	Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.	Alzheimer's disease (late onset)	931 cases, 1,104 controls	1,338 cases, 2,003 controls	19q13.32	19	44878777	PVRL2	NECTIN2			ENSG00000130202	NA	NA	rs6859-A	rs6859	0	6859	3_prime_UTR_variant	0	0.46	1e-07	7		1.41	[1.24-1.60]	Illumina [483399]	N
2010-10-14	20885792	Naj AC	2010-09-23	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20885792	Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.	Alzheimer's disease (late onset)	931 cases, 1,104 controls	1,338 cases, 2,003 controls	6q25.1	6	150885942	MTHFD1L	MTHFD1L			ENSG00000120254	NA	NA	rs11754661-A	rs11754661	0	11754661	intron_variant	0	0.07	2e-10	9.69897000433602		2.1	[1.67-2.64]	Illumina [483399]	N
2009-08-04	19597492	Benjamin EJ	2009-07-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19597492	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.	Atrial fibrillation	3,413 cases, 37,105 referents	2,145 cases, 4,073 controls	16q22.3	16	73017721	ZFHX3	ZFHX3			ENSG00000140836	NA	NA	rs2106261-T	rs2106261	0	2106261	intron_variant	0	0.174	2e-15	14.698970004336		1.25		Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-08-04	19597492	Benjamin EJ	2009-07-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19597492	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.	Atrial fibrillation	3,413 cases, 37,105 referents	2,145 cases, 4,073 controls	1p36.22	1	11792459	NPPA, MTHFR	MTHFR			ENSG00000177000	NA	NA	rs17375901-T	rs17375901	0	17375901	intron_variant	0	0.053	6e-07	6.22184874961636		1.26		Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-08-04	19597492	Benjamin EJ	2009-07-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19597492	Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.	Atrial fibrillation	3,413 cases, 37,105 referents	2,145 cases, 4,073 controls	4q25	4	110787131	PITX2	PITX2 - LINC01438	ENSG00000164093	ENSG00000249519		145008	7272	rs17042171-A	rs17042171	0	17042171	intergenic_variant	1	0.12	4e-63	62.397940008672		1.65		Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-06	21357676	Sulem P	2011-02-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21357676	Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.	Coffee consumption	5,840 European ancestry individuals, 771 Sorbian (founder/genetic isolate) individuals	4,050 European ancestry individuals	15q24.1	15	74735539	CYP1A1, CYP1A2	CYP1A1 - CYP1A2	ENSG00000140465	ENSG00000140505		10003	13306	rs2472297-T	rs2472297	0	2472297	intergenic_variant	1	0.265	5e-14	13.301029995664		0.31	[0.17-0.44] cups per day increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-06	21357676	Sulem P	2011-02-28	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21357676	Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.	Coffee consumption	5,840 European ancestry individuals, 771 Sorbian (founder/genetic isolate) individuals	4,050 European ancestry individuals	7p21.1	7	17247645	AHR	AC073332.1, AHR			ENSG00000237773, ENSG00000106546	NA	NA	rs6968865-T	rs6968865	0	6968865	5_prime_UTR_variant	0	0.593	2e-11	10.698970004336		0.26	[0.15-0.36] cups per day increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-02-02	20066004	Chung CM	2010-01-12	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/20066004	A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.	Angiotensin-converting enzyme activity	400 Han Chinese ancestry hypertensive cases	623 Han Chinese ancestry hypertensive cases	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		3270	23176	rs495828-A	rs495828	0	495828	intergenic_variant	1	0.17	3e-08	7.52287874528034		4.9	[NR] % variance	Illumina [~ 550000]	N
2010-02-02	20066004	Chung CM	2010-01-12	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/20066004	A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor.	Angiotensin-converting enzyme activity	400 Han Chinese ancestry hypertensive cases	623 Han Chinese ancestry hypertensive cases	17q23.3	17	63488670	ACE	AC113554.1, ACE			ENSG00000264813, ENSG00000159640	NA	NA	rs4343-G	rs4343	0	4343	synonymous_variant	0	0.31	3e-25	24.5228787452803		16.2	[NR] % variance	Illumina [~ 550000]	N
2011-01-27	21216876	Sharma S	2011-01-07	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21216876	Genome-wide association studies of adolescent idiopathic scoliosis suggest candidate susceptibility genes.	Adolescent idiopathic scoliosis	1,113 European, African, Oceania, Hispanic and other ancestry individuals from 418 families	562 European ancestry cases, 666 European ancestry controls, 137 cases, 2,126 controls	3p26.3	3	149364	LOC642891, CHL1	CHL1-AS2			ENSG00000224318	NA	NA	rs10510181-A	rs10510181	0	10510181	intron_variant	0	0.33	8e-07	6.09691001300806	(EA)	1.37	[1.20-1.58]	Illumina [326498]	N
2011-04-06	21364930	Bol SM	2011-02-25	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21364930	Genome-wide association study identifies single nucleotide polymorphism in DYRK1A associated with replication of HIV-1 in monocyte-derived macrophages.	HIV-1 replication	191 European ancestry individuals	31 individuals	21q22.13	21	37368522	DYRK1A	DYRK1A			ENSG00000157540	NA	NA	rs12483205-?	rs12483205	0	12483205	intron_variant	0	NR	5e-06	5.30102999566398		NA		Illumina [494656]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	3q13.12	3	107746970	BBX	BBX			ENSG00000114439	NA	NA	rs6437740-?	rs6437740	0	6437740	intron_variant	0	0.24	2e-07	6.69897000433602	(CPD)	0.1	[NR] cigarettes per day decrease	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	1p35.2	1	30094749	intergenic	LINC01648 - AL137076.1	ENSG00000233399	ENSG00000233372		57137	45514	rs910696-?	rs910696	0	910696	intergenic_variant	1	0.31	3e-06	5.52287874528034	(CPD)	0.08	[NR] cigarettes per day increase	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	Xq23	X	111912005	TRPC5	TRPC5			ENSG00000072315	NA	NA	rs7050529-?	rs7050529	0	7050529	intron_variant	0	0.07	6e-06	5.22184874961636	(CPD)	0.06	[NR] cigarettes per day decrease	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	13q33.1	13	103214754	intergenic	SLC10A2 - AL162717.1	ENSG00000125255	ENSG00000285789		148337	128906	rs912969-?	rs912969	0	912969	intergenic_variant	1	0.07	8e-06	5.09691001300806	(SMKDU)	0.14	[NR] years decrease	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	4q31.1	4	139501980	SET7	SETD7			ENSG00000145391	NA	NA	rs17050782-?	rs17050782	0	17050782	intron_variant	0	0.21	8e-06	5.09691001300806	(SMKAGE)	0.03	[NR] years increase	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	14q24.1	14	68941980	ACTN1	ACTN1			ENSG00000072110	NA	NA	rs2268983-?	rs2268983	0	2268983	intron_variant	0	0.51	7e-06	5.15490195998574	(CPDBI)	1.52	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	7p15.2	7	26517999	intergenic	AC004540.1 - KIAA0087	ENSG00000214870	ENSG00000122548		20404	15122	rs886716-?	rs886716	0	886716	intergenic_variant	1	0.69	8e-06	5.09691001300806	(CPDBI)	1.52	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	Xp11.3	X	43747786	MAOA	MAOA - MAOB	ENSG00000189221	ENSG00000069535		962	18824	rs3027409-?	rs3027409	0	3027409	intergenic_variant	1	0.95	7e-06	5.15490195998574	(CPDBI)	1.73	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	3q24	3	144621363	intergenic	AC011592.1 - LARP7P4	ENSG00000280397	ENSG00000244024		175519	902175	rs800082-?	rs800082	0	800082	intergenic_variant	1	0.42	3e-06	5.52287874528034	(PKYRS)	0.12	[NR] pack years increase	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	12q21.2	12	77335605	intergenic	NAV3			ENSG00000067798	NA	NA	rs1402279-?	rs1402279	0	1402279	intron_variant	0	0.95	5e-06	5.30102999566398	(EVNV)	1.51	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	12q21.33	12	90683731	intergenic	LINC02822, AC112481.2			ENSG00000286021, ENSG00000288102	NA	NA	rs1847461-?	rs1847461	0	1847461	non_coding_transcript_exon_variant	0	0.94	8e-06	5.09691001300806	(CIGSTAT)	1.8	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	16p13.3	16	7786295	intergenic	AC005774.1 - AC093515.1	ENSG00000252138	ENSG00000260289		59344	92504	rs3112740-?	rs3112740	0	3112740	intergenic_variant	1	0.86	6e-06	5.22184874961636	(CPDBI)	2.16	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	3q27.2	3	185904041	intergenic	IGF2BP2 - TRA2B	ENSG00000073792	ENSG00000136527		78985	10517	rs6444087-?	rs6444087	0	6444087	intergenic_variant	1	0.26	9e-06	5.04575749056067	(EVNV)	1.28	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	9q31.1	9	101860586	intergenic	MTND3P4 - ARL2BPP7	ENSG00000230302	ENSG00000230418		66830	194666	rs10989661-?	rs10989661	0	10989661	intergenic_variant	1	0.74	6e-06	5.22184874961636	(CIGSTAT)	1.68	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	9p21.2	9	26789942	intergenic	AL451137.2 - AL451137.1	ENSG00000254261	ENSG00000252580		3068	6231	rs1889899-?	rs1889899	0	1889899	regulatory_region_variant	1	0.37	6e-06	5.22184874961636	(EVNV)	1.26	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	5q14.3	5	91466931	LOC133789	ARRDC3-AS1			ENSG00000281357	NA	NA	rs933688-?	rs933688	0	933688	intron_variant	0	0.17	6e-06	5.22184874961636	(EVNV)	1.48	[NR]	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	4q28.1	4	125510764	intergenic	MIR2054 - AC104664.1	ENSG00000283550	ENSG00000250149		3457	165954	rs950063-?	rs950063	0	950063	intergenic_variant	1	0.39	9e-06	5.04575749056067	(SMKDU)	0.08	[NR] years decrease	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	1p22.3	1	87147675	AK002179	LINC01140, AC093155.3			ENSG00000267272, ENSG00000267561	NA	NA	rs7553864-?	rs7553864	0	7553864	intron_variant	0	0.39	3e-06	5.52287874528034	(SMKDU)	0.08	[NR] years increase	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	18q11.2	18	23141009	CABLES1	CABLES1			ENSG00000134508	NA	NA	rs11082304-?	rs11082304	0	11082304	intron_variant	0	0.49	6e-06	5.22184874961636	(SMKAGE)	0.03	[NR] years decrease	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	17p13.2	17	3883613	CAMKK1	CAMKK1			ENSG00000004660	NA	NA	rs758642-?	rs758642	0	758642	intron_variant	0	0.34	7e-06	5.15490195998574	(CPD)	0.08	[NR] cigarettes per day increase	Illumina [~ 518000]	N
2009-04-01	19247474	Caporaso N	2009-02-27	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19247474	Genome-wide and candidate gene association study of cigarette smoking behaviors.	Smoking behavior	2,617 European ancestry smokers, 1,725 European ancestry controls	NA	19p12	19	19925367	ZNF505	ZNF93			ENSG00000184635	NA	NA	rs10411195-?	rs10411195	0	10411195	intron_variant	0	0.03	6e-06	5.22184874961636	(CPD)	0.21	[NR] cigarettes per day decrease	Illumina [~ 518000]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	9q34.2	9	133260148	OBP2A, C9orf96, LOC286310, SURF6, LOC653163, SURF5, ADAMTS13, ABO, OBP2B	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs8176704-A	rs8176704	0	8176704	intron_variant	0	NR	4e-34	33.397940008672	(Conditioned on rs687289)	0.34	[NR] lU/dL decrease	Illumina [723716]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	9q34.2	9;9;9	133261703;133255801;133260148	ABO	ABO; ABO; ABO				NA	NA	rs687289-A; rs8176749-C; rs8176704-G	rs687289; rs8176749; rs8176704	0	NA	intron_variant; synonymous_variant; intron_variant	NA	0.155	4e-98	97.397940008672	(ABO allele - A1)	0.36	[NR] lU/dL increase	Illumina [723716]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	12p13.31	12;12	6044368;6044348	VWF	VWF; VWF				NA	NA	rs1063856-?; rs1063857-?	rs1063856; rs1063857	0	NA	missense_variant; synonymous_variant	NA	NR	6e-07	6.22184874961636		NA		Illumina [723716]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	9q34.2	9	133261703	OBP2A, C9orf96, LOC286310, SURF6, LOC653163, SURF5, ADAMTS13, ABO, OBP2B	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs687289-T	rs687289	0	687289	intron_variant	0	0.751	1e-128	128		0.33	[0.30-0.36] lU/dL increase	Illumina [723716]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	12p13.31	12	6044368	VWF	VWF			ENSG00000110799	NA	NA	rs1063856-A	rs1063856	0	1063856	missense_variant	0	0.395	5e-16	15.301029995664		0.12	[0.091-0.149] lU/dL decrease	Illumina [723716]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	9q34.2	9;9;9	133261703;133255801;133260148	ABO	ABO; ABO; ABO				NA	NA	rs687289-G; rs8176749-C; rs8176704-G	rs687289; rs8176749; rs8176704	0	NA	intron_variant; synonymous_variant; intron_variant	NA	0.72	2e-138	137.698970004336	(ABO allele - O)	0.34	[NR] lU/dL decrease	Illumina [723716]	N
2013-02-21	23267103	Desch KC	2012-12-24	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/23267103	Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association.	Coagulation factor levels	3,250 European ancestry individuals, up to 212 individuals	NA	9q34.2	9;9;9	133261703;133255801;133260148	ABO	ABO; ABO; ABO				NA	NA	rs687289-A; rs8176749-T; rs8176704-G	rs687289; rs8176749; rs8176704	0	NA	intron_variant; synonymous_variant; intron_variant	NA	0.0722	7e-50	49.1549019599857	(ABO allele - B)	0.36	[NR] lU/dL increase	Illumina [723716]	N
2009-06-16	19478329	Aston KI	2009-05-28	J Androl	www.ncbi.nlm.nih.gov/pubmed/19478329	Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.	Male infertility	52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls	NA	20q13.2	20	51943113	SALL4	RNU7-6P - ZFP64	ENSG00000252654	ENSG00000020256		38083	108550	rs6068020-?	rs6068020	0	6068020	intergenic_variant	1	0.49	5e-07	6.30102999566398	(azoospermia)	NA		Illumina [314776]	N
2009-06-16	19478329	Aston KI	2009-05-28	J Androl	www.ncbi.nlm.nih.gov/pubmed/19478329	Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.	Male infertility	52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls	NA	3q11.2	3	95969999	ARL6	AC106719.1 - AC107304.1	ENSG00000286516	ENSG00000271671		50447	274733	rs9814870-?	rs9814870	0	9814870	intergenic_variant	1	0.15	7e-07	6.15490195998574	(oligozoospermia)	NA		Illumina [314776]	N
2009-06-16	19478329	Aston KI	2009-05-28	J Androl	www.ncbi.nlm.nih.gov/pubmed/19478329	Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.	Male infertility	52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls	NA	12p12.2	12	20368720	PDE3A	AC129102.1			ENSG00000256879	NA	NA	rs10841496-?	rs10841496	0	10841496	intron_variant	0	0.58	5e-07	6.30102999566398	(azoospermia)	NA		Illumina [314776]	N
2009-06-16	19478329	Aston KI	2009-05-28	J Androl	www.ncbi.nlm.nih.gov/pubmed/19478329	Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.	Male infertility	52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls	NA	12p13.32	12	3705072	EFCAB4B	CRACR2A			ENSG00000130038	NA	NA	rs10848911-?	rs10848911	0	10848911	intron_variant	0	0.11	4e-06	5.39794000867204	(azoospermia)	NA		Illumina [314776]	N
2009-06-16	19478329	Aston KI	2009-05-28	J Androl	www.ncbi.nlm.nih.gov/pubmed/19478329	Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia.	Male infertility	52 European ancestry oligozoospermic cases, 40 European ancestry non-obstructive azoospermic cases, 80 European ancestry controls	NA	2q22.1	2	139390262	NXPH2	AC062021.1 - AC016710.1	ENSG00000226939	ENSG00000229131		11115	79513	rs1399645-?	rs1399645	0	1399645	intergenic_variant	1	0.02	9e-07	6.04575749056067	(azoospermia)	NA		Illumina [314776]	N
2011-01-27	21221998	Kim JJ	2011-01-09	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/21221998	A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.	Kawasaki disease	186 Korean ancestry child cases, 600 Korean ancestry controls	514 East Asian ancestry child cases, 1,042 East Asian ancestry controls	2p14	2	64122068	PELI1	PELI1			ENSG00000197329	NA	NA	rs7604693-G	rs7604693	0	7604693	intron_variant	0	0.05	2e-06	5.69897000433602	(CAL)	2.7	[1.77-4.12]	Affymetrix [641760]	N
2011-01-27	21221998	Kim JJ	2011-01-09	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/21221998	A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.	Kawasaki disease	186 Korean ancestry child cases, 600 Korean ancestry controls	514 East Asian ancestry child cases, 1,042 East Asian ancestry controls	1p32.2	1	58292243	DAB1	DAB1			ENSG00000173406	NA	NA	rs527409-T	rs527409	0	527409	intron_variant	0	0.02	1e-06	6	(KD)	2.9	[1.85-4.54]	Affymetrix [641760]	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	4q28.1	4	125438301	FAT4	FAT4			ENSG00000196159	NA	NA	rs1395241-?	rs1395241	0	1395241	intron_variant	0	NR	8e-06	5.09691001300806		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	15q14	15	38694167	C15orf53	LINC02694			ENSG00000175779	NA	NA	rs12912251-?	rs12912251	0	12912251	intron_variant	0	NR	1e-06	6		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	7q21.12	7	87192664	C7orf23, DMTF1	DMTF1			ENSG00000135164	NA	NA	rs11773103-?	rs11773103	0	11773103	non_coding_transcript_exon_variant	0	NR	1e-06	6		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	12p13.33	12	2236129	CACNA1C	CACNA1C, CACNA1C			ENSG00000151067, ENSG00000285479	NA	NA	rs1006737-?	rs1006737	0	1006737	intron_variant	0	NR	3e-08	7.52287874528034		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	6q25.2	6	152417619	SYNE1	SYNE1			ENSG00000131018	NA	NA	rs17082664-?	rs17082664	0	17082664	intron_variant	0	NR	1e-06	6		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	13q14.3	13	50492487	intergenic	DLEU1			ENSG00000176124	NA	NA	rs1262778-?	rs1262778	0	1262778	intron_variant	0	NR	8e-06	5.09691001300806		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	10q21.2	10	60421370	ANK3	ANK3			ENSG00000151150	NA	NA	rs10994338-?	rs10994338	0	10994338	intron_variant	0	NR	5e-07	6.30102999566398		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	18p11.32	18	278796	COLEC12, THOC1	AP000845.1 - COLEC12	ENSG00000263884	ENSG00000158270		8518	37941	rs7226677-?	rs7226677	0	7226677	intergenic_variant	1	NR	4e-06	5.39794000867204		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2010-04-15	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder or major depressive disorder	4,387 European and unknown ancestry bipolar disorder cases, 1,695 major depressive disorder cases, 7,970 European and unknown ancestry controls	NA	2q31.1	2	175375121	intergenic	AC093459.1			ENSG00000229066	NA	NA	rs4972755-?	rs4972755	0	4972755	intron_variant	0	NR	3e-06	5.52287874528034		NA		Affymetrix, Perlegen [1472580] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	2q11.2	2	96747751	LMAN2L, FER1L5, CNNM4	LMAN2L - CNNM4	ENSG00000114988	ENSG00000158158		7687	13151	rs2314398-?	rs2314398	0	2314398	regulatory_region_variant	1	NR	3e-06	5.52287874528034		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	3p24.3	3	21664877	ZNF385D	ZNF385D			ENSG00000151789	NA	NA	rs3821396-?	rs3821396	0	3821396	intron_variant	0	NR	5e-06	5.30102999566398		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	6q25.2	6	152417619	SYNE1	SYNE1			ENSG00000131018	NA	NA	rs17082664-?	rs17082664	0	17082664	intron_variant	0	NR	4e-06	5.39794000867204		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	9q33.3	9	127347467	GARNL3, SLC2A8	GARNL3			ENSG00000136895	NA	NA	rs7041940-?	rs7041940	0	7041940	intron_variant	0	NR	3e-06	5.52287874528034		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	10q21.2	10	60420054	ANK3	ANK3			ENSG00000151150	NA	NA	rs109944336-?	rs10994336	0	10994336	intron_variant	0	NR	9e-09	8.04575749056067		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	10q21.2	10	60540625	intergenic	ANK3			ENSG00000151150	NA	NA	rs1938526-?	rs1938526	0	1938526	intron_variant	0	NR	1e-08	8		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	11q14.1	11	79372576	hsa-mir-708, ODZ4	TENM4			ENSG00000149256	NA	NA	rs12290811-?	rs12290811	0	12290811	intron_variant	0	NR	4e-06	5.39794000867204		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	11q24.2	11	124668099	PAN3, SIAE, SPA17, TBRG1	SIAE			ENSG00000110013	NA	NA	rs544368-?	rs544368	0	544368	intron_variant	0	NR	6e-06	5.22184874961636		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	12p13.33	12	2236129	CACNA1C	CACNA1C, CACNA1C			ENSG00000151067, ENSG00000285479	NA	NA	rs1006737-?	rs1006737	0	1006737	intron_variant	0	NR	7e-08	7.15490195998574		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	14q11.2	14	23912306	C14orf165, C14orf167, DHRS4	AL136419.2 - LINC00596	ENSG00000285727	ENSG00000259334		29878	9941	rs12436436-?	rs12436436	0	12436436	intergenic_variant	1	NR	5e-06	5.30102999566398		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	15q14	15	38703290	C15orf53	LINC02694			ENSG00000175779	NA	NA	rs12899449-?	rs12899449	0	12899449	intron_variant	0	NR	4e-07	6.39794000867204		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	4q26	4	119514966	COLEC12, THOC1	PDE5A, AC093752.1			ENSG00000138735, ENSG00000245958	NA	NA	rs722667-?	rs722667	0	722667	intron_variant	0	NR	7e-06	5.15490195998574		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	9p13.3	9	33799372	PRSS3, UBE2R2	UBE2R2-AS1			ENSG00000235481	NA	NA	rs216345-?	rs216345	0	216345	intron_variant	0	NR	4e-06	5.39794000867204		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	15q25.1	15	80402580	ARNT2	AC016705.2			ENSG00000259495	NA	NA	rs2278702-?	rs2278702	0	2278702	intron_variant	0	NR	6e-06	5.22184874961636		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	1p21.2	1	101475100	intergenic	LINC01307 - LINC01709	ENSG00000231671	ENSG00000226715		84797	164409	rs1419103-?	rs1419103	0	1419103	intergenic_variant	1	NR	6e-06	5.22184874961636		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	3p26.2	3	3617156	intergenic	AC034195.1			ENSG00000223727	NA	NA	rs1601875-?	rs1601875	0	1601875	intron_variant	0	NR	7e-06	5.15490195998574		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	9p13.3	9	33942932	UBE2R2, UBAP2, SNORD121B, SNORD121A	UBAP2			ENSG00000137073	NA	NA	rs307660-?	rs307660	0	307660	intron_variant	0	NR	5e-06	5.30102999566398		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	9q31.3	9	110434983	SVEP1	SVEP1			ENSG00000165124	NA	NA	rs7042161-?	rs7042161	0	7042161	intron_variant	0	NR	6e-06	5.22184874961636		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	15q14	15	38219782	SPRED1	AC087473.1			ENSG00000259380	NA	NA	rs16966460-?	rs16966460	0	16966460	intron_variant	0	NR	4e-06	5.39794000867204		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	10q22.3	10	79195310	ZMIZ1	ZMIZ1			ENSG00000108175	NA	NA	rs703965-?	rs703965	0	703965	intron_variant	0	NR	8e-06	5.09691001300806		NA		Affymetrix [1769948] (imputed)	N
2019-01-10	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Bipolar disorder	4,387 European and unknown ancestry cases, 6,209 European and unknown ancestry controls	NA	18p11.32	18	278796	COLEC12, THOC1	AP000845.1 - COLEC12	ENSG00000263884	ENSG00000158270		8518	37941	rs7226677-?	rs7226677	0	7226677	intergenic_variant	1	NR	7e-06	5.15490195998574		NA		Affymetrix [1769948] (imputed)	N
2018-11-14	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Major depressive disorder	1,695 cases, 1,761 controls	NA	3q12.1	3	98969178	intergenic	AC091212.1			ENSG00000239462	NA	NA	rs1481631-?	rs1481631	0	1481631	intron_variant	0	NR	2e-06	5.69897000433602		NA		Perlegen [1893617] (imputed)	N
2018-11-14	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Major depressive disorder	1,695 cases, 1,761 controls	NA	7q21.11	7	82825088	PCLO	PCLO			ENSG00000186472	NA	NA	rs2247523-?	rs2247523	0	2247523	intron_variant	0	NR	5e-06	5.30102999566398		NA		Perlegen [1893617] (imputed)	N
2018-11-14	20351715	Liu Y	2010-03-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20351715	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	Major depressive disorder	1,695 cases, 1,761 controls	NA	10p11.22	10	33968684	intergenic	LINC02629 - PARD3	ENSG00000223470	ENSG00000148498		50880	140876	rs1780436-?	rs1780436	0	1780436	intergenic_variant	1	NR	7e-06	5.15490195998574		NA		Perlegen [1893617] (imputed)	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	13q12.11	13	21730960	intergenic	FGF9 - RN7SL766P	ENSG00000102678	ENSG00000244197		26462	59577	rs518590-?	rs518590	0	518590	intergenic_variant	1	0.21	2e-07	6.69897000433602	(quetiapine-HDL)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	9q31.1	9	102182473	intergenic	ARL2BPP7 - RNU6-329P	ENSG00000230418	ENSG00000238882		126732	74131	rs320209-?	rs320209	0	320209	intergenic_variant	1	0.068	4e-07	6.39794000867204	(clozapine-glucose)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	12p12.1	12	24236726	SOX5	SOX5, SOX5-AS1			ENSG00000134532, ENSG00000256120	NA	NA	rs1464500-?	rs1464500	0	1464500	intron_variant	0	0.232	1e-07	7	(perphenazine-HDL)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	16p13.12	16	13160099	LOC729993	SHISA9			ENSG00000237515	NA	NA	rs153091-?	rs153091	0	153091	intron_variant	0	0.227	2e-06	5.69897000433602	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	4q23	4	99792608	intergenic	C4orf54 - DAPP1	ENSG00000248713	ENSG00000070190		137960	24219	rs11735070-?	rs11735070	0	11735070	intergenic_variant	1	0.338	1e-06	6	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	8q22.3	8	104980468	intergenic	ZFPM2			ENSG00000169946	NA	NA	rs977396-?	rs977396	0	977396	intron_variant	0	0.089	3e-07	6.52287874528034	(olanzapine-total cholesterol)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	10p11.23	10	31077342	intergenic	AL359546.1			ENSG00000287564	NA	NA	rs2994684-?	rs2994684	0	2994684	intron_variant	0	0.155	3e-07	6.52287874528034	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	16q23.3	16	83453866	CDH13	CDH13			ENSG00000140945	NA	NA	rs17216786-?	rs17216786	0	17216786	intron_variant	0	0.054	1e-06	6	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	1p21.2	1	101086370	intergenic	AC093157.1			ENSG00000233184	NA	NA	rs17410015-?	rs17410015	0	17410015	intron_variant	0	0.063	2e-06	5.69897000433602	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p25.3	2	1773378	intergenic	PXDN - MYT1L	ENSG00000130508	ENSG00000186487		28526	15735	rs6735179-?	rs6735179	0	6735179	regulatory_region_variant	1	0.346	1e-07	7	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p16.1	2	60273009	intergenic	AC007100.1 - AC007381.1	ENSG00000271955	ENSG00000228590		172809	63437	rs10202231-?	rs10202231	0	10202231	intergenic_variant	1	0.457	7e-07	6.15490195998574	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p12	2	79460126	intergenic	CTNNA2			ENSG00000066032	NA	NA	rs399885-?	rs399885	0	399885	intron_variant	0	0.327	5e-07	6.30102999566398	(clozapine-heart rate)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	5q14.3	5	91003406	GPR98	ADGRV1			ENSG00000164199	NA	NA	rs1967256-?	rs1967256	0	1967256	intron_variant	0	0.148	3e-08	7.52287874528034	(olanzapine-hemoglobin A1c	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	6q14.3	6	85982222	intergenic	AL450338.2			ENSG00000288021	NA	NA	rs1577917-?	rs1577917	0	1577917	intron_variant	0	0.21	3e-06	5.52287874528034	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p12	2	79482228	intergenic	CTNNA2			ENSG00000066032	NA	NA	rs7570469-?	rs7570469	0	7570469	intron_variant	0	0.418	6e-07	6.22184874961636	(clozapine-heart rate)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p11.2	2	84123793	intergenic	ST6GALNAC2P1 - FUNDC2P2	ENSG00000228902	ENSG00000182814		83073	166890	rs1534238-?	rs1534238	0	1534238	intergenic_variant	1	0.381	3e-06	5.52287874528034	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	4q24	4	101010669	intergenic	EMCN - PPP3CA	ENSG00000164035	ENSG00000138814		130543	12740	rs1405687-?	rs1405687	0	1405687	regulatory_region_variant	1	0.088	5e-08	7.30102999566398	(ziprasidone-hip circumference)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	18q12.2	18	36527489	FHOD3	FHOD3			ENSG00000134775	NA	NA	rs17651157-?	rs17651157	0	17651157	intron_variant	0	0.068	1e-07	7	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	6p21.31	6	35395980	PPARD	PPARD			ENSG00000112033	NA	NA	rs9658108-?	rs9658108	0	9658108	intron_variant	0	0.052	5e-07	6.30102999566398	(clozapine-glucose)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	10p12.33	10	18108318	intergenic	SLC39A12 - CACNB2	ENSG00000148482	ENSG00000165995		65026	32359	rs17661538-?	rs17661538	0	17661538	intergenic_variant	1	0.138	1e-06	6	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	11q24.2	11	126989261	KIRREL3	KIRREL3			ENSG00000149571	NA	NA	rs620875-?	rs620875	0	620875	intron_variant	0	0.101	3e-06	5.52287874528034	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	15q14	15	37057601	MEIS2	MEIS2			ENSG00000134138	NA	NA	rs1568679-?	rs1568679	0	1568679	intron_variant	0	0.103	1e-08	8	(risperidone-hip circumference)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	20q13.2	20	55184590	intergenic	RPL12P4 - LINC01440	ENSG00000185834	ENSG00000235166		109450	224308	rs6092078-?	rs6092078	0	6092078	intergenic_variant	1	0.115	3e-06	5.52287874528034	(risperidone-hip circumference)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	1p31.1	1	82846152	intergenic	AL157944.1			ENSG00000233290	NA	NA	rs11163585-?	rs11163585	0	11163585	intron_variant	0	0.24	9e-07	6.04575749056067	(perphenazine-HDL)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	11q23.1	11	112585498	intergenic	LINC02763			ENSG00000254968	NA	NA	rs7105881-?	rs7105881	0	7105881	intron_variant	0	0.367	3e-07	6.52287874528034	(risperidone-hip circumference)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	14q32.13	14	95205534	CLMN	CLMN			ENSG00000165959	NA	NA	rs1187614-?	rs1187614	0	1187614	intron_variant	0	0.313	2e-07	6.69897000433602	(perphenazine-total cholesterol)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	16p13.13	16	10465406	ATF7IP2	ATF7IP2			ENSG00000166669	NA	NA	rs13335336-?	rs13335336	0	13335336	intron_variant	0	0.078	7e-07	6.15490195998574	(risperidone-hemoglobin A1c)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	16q23.3	16	82560778	intergenic	AC009117.2			ENSG00000261285	NA	NA	rs4783227-?	rs4783227	0	4783227	intron_variant	0	0.424	4e-07	6.39794000867204	(olanzapine-total cholesterol)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	18q22.2	18	70475178	intergenic	RPS2P6 - AC091305.1	ENSG00000214255	ENSG00000278971		44053	14452	rs8092443-?	rs8092443	0	8092443	intergenic_variant	1	0.225	1e-06	6	(risperidone-hemoglobin A1c)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	18q22.2	18	70486384	intergenic	RPS2P6 - AC091305.1	ENSG00000214255	ENSG00000278971		55259	3246	rs11663206-?	rs11663206	0	11663206	intergenic_variant	1	0.289	2e-06	5.69897000433602	(risperidone-hemoglobin A1c)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	7p21.1	7	17521959	intergenic	AC019117.1			ENSG00000236039	NA	NA	rs10499504-?	rs10499504	0	10499504	intron_variant	0	0.11	4e-07	6.39794000867204	(clozapine-total cholesterol)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p25.1	2	7007842	RNF144A	RNF144A			ENSG00000151692	NA	NA	rs6741819-?	rs6741819	0	6741819	intron_variant	0	0.305	2e-07	6.69897000433602	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2q33.1	2	201942473	intergenic	RNU6-440P - AC069148.1	ENSG00000212184	ENSG00000273209		14930	90297	rs17385675-?	rs17385675	0	17385675	intergenic_variant	1	0.069	3e-06	5.52287874528034	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	5q31.3	5	143624040	intergenic	AC008696.2			ENSG00000249881	NA	NA	rs17100498-?	rs17100498	0	17100498	intron_variant	0	0.126	5e-07	6.30102999566398	(risperidone-hemoglobin A1c)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	7q22.3	7	107122773	PRKAR2B	AC006387.1, PRKAR2B, PRKAR2B			ENSG00000243193, ENSG00000284096, ENSG00000005249	NA	NA	rs13224682-?	rs13224682	0	13224682	intron_variant	0	0.072	6e-08	7.22184874961636	(clozapine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	9q33.1	9	117164147	ASTN2	ASTN2			ENSG00000148219	NA	NA	rs4838255-?	rs4838255	0	4838255	intron_variant	0	0.139	3e-07	6.52287874528034	(perphenazine-triglycerides)	NA		Affymetrix [492900]	N
2010-04-06	20195266	Adkins DE	2010-03-02	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20195266	Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.	Response to antipsychotic treatment	421 European ancestry, 214 African American, and 103 cases	NA	2p24.1	2	21617221	intergenic	AC018742.1, AC009411.2			ENSG00000233005, ENSG00000235537	NA	NA	rs1117324-?	rs1117324	0	1117324	intron_variant	0	0.156	3e-07	6.52287874528034	(risperidone-hip circumference)	NA		Affymetrix [492900]	N
2012-06-19	22508271	Rasmussen-Torvik LJ	2012-04-16	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/22508271	Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).	Fasting plasma glucose	2,349 European ancestry individuals, 664 Chinese ancestry individuals, 1,366 African American individuals, 1,171 Hispanic individuals	NA	11q14.3	11	92975544	MTNR1B	MTNR1B			ENSG00000134640	NA	NA	rs10830963-G	rs10830963	0	10830963	intron_variant	0	0.27	1e-12	12	(Fasting glucose)	1.38	[1.01-1.75] mg/dL increase	Affymetrix [NR] (imputed)	N
2012-06-19	22508271	Rasmussen-Torvik LJ	2012-04-16	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/22508271	Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).	Fasting plasma glucose	2,349 European ancestry individuals, 664 Chinese ancestry individuals, 1,366 African American individuals, 1,171 Hispanic individuals	NA	7p13	7	44196069	GCKR	GCK			ENSG00000106633	NA	NA	rs4607517-G	rs4607517	0	4607517	intron_variant	0	0.19	1e-07	7	(fasting gluocse)	1.15	[0.72-1.58] mg/dL decrease	Affymetrix [NR] (imputed)	N
2012-06-19	22508271	Rasmussen-Torvik LJ	2012-04-16	Genet Epidemiol	www.ncbi.nlm.nih.gov/pubmed/22508271	Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).	Fasting plasma glucose	2,349 European ancestry individuals, 664 Chinese ancestry individuals, 1,366 African American individuals, 1,171 Hispanic individuals	NA	2q31.1	2	168906638	G6PC2	SPC25, SPC25, G6PC2, G6PC2			ENSG00000152253, ENSG00000277909, ENSG00000152254, ENSG00000278373	NA	NA	rs560887-T	rs560887	0	560887	intron_variant	0	0.20	2e-06	5.69897000433602	(fasting glucose)	1.29	[0.84-1.74] mg/dL decrease	Affymetrix [NR] (imputed)	N
2010-05-23	20418489	Qi L	2010-04-23	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20418489	Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes.	Type 2 diabetes	2,591 European ancestry cases, 3,052 European ancestry controls	10,870 European ancestry cases, 73,735 European ancestry controls	2q24.2	2	160314943	ITGB6, RBMS1	RBMS1			ENSG00000153250	NA	NA	rs7593730-?	rs7593730	0	7593730	intron_variant	0	0.78	4e-08	7.39794000867204		1.11	[1.08-1.16]	Affymetrix [683509]	N
2012-06-18	22524403	Rice JP	2012-04-24	Addiction	www.ncbi.nlm.nih.gov/pubmed/22524403	CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results.	Nicotine dependence	2,267 European ancestry individuals, 99 Hispanic individuals, 999 African American individuals	835 individuals	8p11.21	8	42691568	CHRNB3	SMIM19 - CHRNB3	ENSG00000176209	ENSG00000147432		136375	5798	rs1451240-?	rs1451240	0	1451240	intergenic_variant	1	NR	7e-16	15.1549019599857		NA		Illumina [948658]	N
2009-03-28	19270707	Birnbaum S	2009-03-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19270707	Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.	Orofacial clefts	224 European ancestry cases, 383 European ancestry controls	246 cases, 954 controls	1q32.2	1	209815925	IRF6	IRF6 - UTP25	ENSG00000117595	ENSG00000117597		9750	12047	rs642961-A	rs642961	0	642961	intergenic_variant	1	NR	2e-06	5.69897000433602		NA		Illumina [521176]	N
2009-03-28	19270707	Birnbaum S	2009-03-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19270707	Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.	Orofacial clefts	224 European ancestry cases, 383 European ancestry controls	246 cases, 954 controls	8q24.21	8	128933908	GSDMC, PVT1	CCDC26			ENSG00000229140	NA	NA	rs987525-A	rs987525	0	987525	intron_variant	0	0.20	3e-24	23.5228787452803		2.57	[2.02-3.26]	Illumina [521176]	N
2010-09-14	20675712	Reed DR	2010-07-31	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20675712	The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.	Bitter taste response	1,457 European ancestry individuals	73 European ancestry individuals	7q34	7	141973545	TAS2R38	MGAM, TAS2R38			ENSG00000257335, ENSG00000257138	NA	NA	rs713598-?	rs713598	0	713598	missense_variant	0	0.40	2e-104	103.698970004336	(PROP)	NA		Illumina [~ 2300000] (imputed)	N
2012-08-08	22694956	Cipriani V	2012-06-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22694956	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	Age-related macular degeneration	893 European ancestry cases, 2,199 European ancestry controls	1,411 European ancestry cases, 1,431 European ancestry controls	10q26.13	10	122454932	ARMS2, HTRA1	ARMS2, BX842242.1			ENSG00000254636, ENSG00000285955	NA	NA	rs10490924-T	rs10490924	0	10490924	missense_variant	0	0.21	3e-72	71.5228787452803		3	[2.64-3.40]	Illumina [2272849] (imputed)	N
2012-08-08	22694956	Cipriani V	2012-06-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22694956	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	Age-related macular degeneration	893 European ancestry cases, 2,199 European ancestry controls	1,411 European ancestry cases, 1,431 European ancestry controls	1q31.3	1	196691131	CFH	CFH			ENSG00000000971	NA	NA	rs10801555-A	rs10801555	0	10801555	intron_variant	0	0.40	2e-47	46.698970004336		2.33	[2.08-2.63]	Illumina [2272849] (imputed)	N
2012-08-08	22694956	Cipriani V	2012-06-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22694956	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	Age-related macular degeneration	893 European ancestry cases, 2,199 European ancestry controls	1,411 European ancestry cases, 1,431 European ancestry controls	6p21.32	6	32107027	TNXB	TNXB, TNXB, TNXB, TNXB, TNXB, TNXB, AL662884.2			ENSG00000168477, ENSG00000206258, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000236221, ENSG00000284829	NA	NA	rs12153855-C	rs12153855	0	12153855	intron_variant	0	0.011	1e-09	9		1.44	[1.28-1.63]	Illumina [2272849] (imputed)	N
2012-08-08	22694956	Cipriani V	2012-06-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22694956	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	Age-related macular degeneration	893 European ancestry cases, 2,199 European ancestry controls	1,411 European ancestry cases, 1,431 European ancestry controls	6p21.32	6	32203906	NOTCH4	NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4			ENSG00000235396, ENSG00000223355, ENSG00000204301, ENSG00000232339, ENSG00000234876, ENSG00000206312, ENSG00000238196	NA	NA	rs2071277-C	rs2071277	0	2071277	intron_variant	0	0.219	2e-11	10.698970004336		1.3	[1.20-1.41]	Illumina [2272849] (imputed)	N
2012-08-08	22694956	Cipriani V	2012-06-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22694956	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	Age-related macular degeneration	893 European ancestry cases, 2,199 European ancestry controls	1,411 European ancestry cases, 1,431 European ancestry controls	6p21.33	6	31949174	CFB	CFB, CFB, CFB, CFB, CFB, CFB, AL645922.1			ENSG00000243649, ENSG00000239754, ENSG00000242335, ENSG00000241534, ENSG00000241253, ENSG00000243570, ENSG00000244255	NA	NA	rs541862-T	rs541862	0	541862	non_coding_transcript_exon_variant	0	0.99	9e-17	16.0457574905607		1.89	[1.61-2.17]	Illumina [2272849] (imputed)	N
2012-08-08	22694956	Cipriani V	2012-06-13	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22694956	Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.	Age-related macular degeneration	893 European ancestry cases, 2,199 European ancestry controls	1,411 European ancestry cases, 1,431 European ancestry controls	19q13.32	19	44892362	TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-A	rs2075650	0	2075650	intron_variant	0	0.851	8e-08	7.09691001300806		1.37	[1.22-1.54]	Illumina [2272849] (imputed)	N
2012-03-10	22327514	Postel-Vinay S	2012-02-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22327514	Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.	Ewing sarcoma	Up to 427 European ancestry cases, up to 4,352 European ancestry controls	661 European ancestry cases, 1,299 European ancestry controls	1p36.22	1	10986798	TARDBP	C1orf127 - CFL1P6	ENSG00000175262	ENSG00000215785		4761	4180	rs9430161-G	rs9430161	0	9430161	intergenic_variant	1	0.79	1e-20	20		2.2	[1.77-2.72]	NR [286966]	N
2012-03-10	22327514	Postel-Vinay S	2012-02-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22327514	Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.	Ewing sarcoma	Up to 427 European ancestry cases, up to 4,352 European ancestry controls	661 European ancestry cases, 1,299 European ancestry controls	15q15.1	15	40047293	BMF, SRP14, EIF2AK4	SRP14-AS1			ENSG00000248508	NA	NA	rs4924410-A	rs4924410	0	4924410	intron_variant	0	0.27	7e-09	8.15490195998574		1.46	[1.23-1.74]	NR [286966]	N
2012-03-10	22327514	Postel-Vinay S	2012-02-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22327514	Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.	Ewing sarcoma	Up to 427 European ancestry cases, up to 4,352 European ancestry controls	661 European ancestry cases, 1,299 European ancestry controls	10q21.3	10	62820815	EGR2, ADO, ZNF365	EGR2			ENSG00000122877	NA	NA	rs224278-C	rs224278	0	224278	intron_variant	0	0.58	4e-17	16.397940008672		1.66	[1.42-1.93]	NR [286966]	N
2012-05-25	22511988	Jylhava J	2012-04-12	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22511988	A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.	Circulating cell-free DNA	1,841 individuals	NA	2q37.1	2	233763993	UGT1A1	UGT1A9, UGT1A5, UGT1A8, UGT1A6, UGT1A3, UGT1A7, UGT1A10, UGT1A1, UGT1A4			ENSG00000241119, ENSG00000240224, ENSG00000242366, ENSG00000167165, ENSG00000243135, ENSG00000244122, ENSG00000242515, ENSG00000241635, ENSG00000244474	NA	NA	rs6742078-T	rs6742078	0	6742078	intron_variant	0	0.60	2e-23	22.698970004336		0.3358	[0.27-0.40] ug/ml increase	Illumina [2543887] (imputed)	N
2009-03-24	19268274	Liu XG	2009-03-04	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19268274	Genome-wide association and replication studies identified TRHR as an important gene for lean body mass.	Body mass (lean)	973 European ancestry individuals	1,488 European ancestry individuals,  1,972 European ancestry individuals from 593 families, 2,955 Chinese ancestry individuals	8q23.1	8	109103447	TRHR	TRHR			ENSG00000174417	NA	NA	rs7832552-T	rs7832552	0	7832552	intron_variant	0	0.32	4e-10	9.39794000867204		0.1	[0.04-0.16] kg increase	Affymetrix [379319]	N
2012-05-16	22472174	Xiao Y	2012-04-03	Clin Cancer Res	www.ncbi.nlm.nih.gov/pubmed/22472174	SSBP2 variants are associated with survival in glioblastoma patients.	Glioblastoma	315 European ancestry cases	434 European ancestry cases	5q14.1	5	81423306	SSBP2	SSBP2			ENSG00000145687	NA	NA	rs7732320-T	rs7732320	0	7732320	intron_variant	0	0.11	1e-06	6		1.64	[1.34-2.00]	Illumina [314635]	N
2012-04-28	22479309	Boraska V	2012-03-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22479309	Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts.	Brachial circumference	18,753 European ancestry individuals	3,623 European ancestry individuals	7q21.12	7	87067398	GRM3, DMTF1	KIAA1324L - AC004023.1	ENSG00000164659	ENSG00000261462		7744	42141	rs1476587-G	rs1476587	0	1476587	intergenic_variant	1	0.141	7e-06	5.15490195998574		0.283	[0.16-0.41] unit increase	Affymetrix, Illumina [2238430] (imputed)	N
2012-04-06	22419738	Osman W	2012-03-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22419738	A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.	Glaucoma (primary open-angle)	1,394 Japanese ancestry cases, 6,599 Japanese ancestry controls	1,802 Japanese ancestry cases, 7,212 Japanese ancestry controls	2q21.2	2	133605461	NCKAP5	RN7SKP93 - AC092623.1	ENSG00000200708	ENSG00000286697		9062	423147	rs7588567-G	rs7588567	0	7588567	regulatory_region_variant	1	0.586	4e-07	6.39794000867204		1.18	[1.10-1.25]	Illumina [602216]	N
2012-04-06	22419738	Osman W	2012-03-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22419738	A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.	Glaucoma (primary open-angle)	1,394 Japanese ancestry cases, 6,599 Japanese ancestry controls	1,802 Japanese ancestry cases, 7,212 Japanese ancestry controls	9p21.3	9	22003368	CDKN2B	CDKN2B, AL359922.1, CDKN2B-AS1			ENSG00000147883, ENSG00000264545, ENSG00000240498	NA	NA	rs1063192-T	rs1063192	0	1063192	3_prime_UTR_variant	0	0.79	5e-11	10.301029995664		1.33	[1.22-1.43]	Illumina [602216]	N
2012-04-06	22419738	Osman W	2012-03-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22419738	A genome-wide association study in the Japanese population confirms 9p21 and 14q23 as susceptibility loci for primary open angle glaucoma.	Glaucoma (primary open-angle)	1,394 Japanese ancestry cases, 6,599 Japanese ancestry controls	1,802 Japanese ancestry cases, 7,212 Japanese ancestry controls	14q23.1	14	60606157	SIX6, SIX1	AL049874.1 - SALRNA1	ENSG00000241354	ENSG00000258952		3624	33059	rs10483727-T	rs10483727	0	10483727	intergenic_variant	1	0.768	9e-08	7.04575749056067		1.27	[1.18-1.37]	Illumina [602216]	N
2013-09-26	23652523	Mayerle J	2013-05-08	JAMA	www.ncbi.nlm.nih.gov/pubmed/23652523	Identification of genetic loci associated with Helicobacter pylori serologic status.	Helicobacter pylori serologic status	2,623 European ancestry high titer cases, 7,862 European ancestry low or no titer controls	NA	4p14	4	38783103	FAM114A1, TLR10, TLR1, TLR6, KLF3	TLR10 - TLR1	ENSG00000174123	ENSG00000174125		113	7574	rs10004195-A	rs10004195	0	10004195	regulatory_region_variant	1	0.75	1e-18	18		1.43	[1.32-1.54]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-09-26	23652523	Mayerle J	2013-05-08	JAMA	www.ncbi.nlm.nih.gov/pubmed/23652523	Identification of genetic loci associated with Helicobacter pylori serologic status.	Helicobacter pylori serologic status	2,623 European ancestry high titer cases, 7,862 European ancestry low or no titer controls	NA	1q23.3	1	161514420	FCGR2A, HSPA6	AL590385.2, FCGR2A			ENSG00000273112, ENSG00000143226	NA	NA	rs368433-C	rs368433	0	368433	intron_variant	0	0.84	2e-08	7.69897000433602		1.37	[1.23-1.54]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-05-24	22479191	Pattaro C	2012-03-29	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22479191	Genome-wide association and functional follow-up reveals new loci for kidney function.	Chronic kidney disease	74,354  European ancestry individuals	56,246 European ancestry individuals	11p14.1	11	30738788	MPPED2	MPPED2-AS1 - AL122014.1	ENSG00000254489	ENSG00000287373		106205	35125	rs3925584-?	rs3925584	0	3925584	intergenic_variant	1	NR	8e-18	17.0969100130081		0.0075	[0.0057-0.0093] ml/min/1.73m^2 decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-05-24	22479191	Pattaro C	2012-03-29	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22479191	Genome-wide association and functional follow-up reveals new loci for kidney function.	Chronic kidney disease	74,354  European ancestry individuals	56,246 European ancestry individuals	2p24.3	2	15722878	DDX1	LINC01804			ENSG00000231031	NA	NA	rs6431731-?	rs6431731	0	6431731	intron_variant	0	NR	4e-08	7.39794000867204		0.0127	[0.0082-0.0172] ml/min/1.73m^2 decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	1p36.12	1	22371954	RP11-415K20.1, WNT4	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		5472	56884	rs7524102-G	rs7524102	0	7524102	intergenic_variant	1	0.21	3e-09	8.52287874528034		1.28	[1.17-1.41]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	6q25.1	6	149441401	ZC3H12D, TAB2	TAB2 - ZC3H12D	ENSG00000055208	ENSG00000178199		29788	5394	rs2179367-G	rs2179367	0	2179367	regulatory_region_variant	1	0.42	3e-07	6.52287874528034		1.23	[1.14-1.32]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	7p14.1	7	37949493	EPDR1, SFRP4	SFRP4, EPDR1			ENSG00000106483, ENSG00000086289	NA	NA	rs16879765-A	rs16879765	0	16879765	intron_variant	0	0.19	6e-39	38.2218487496164		1.98	[1.78-2.18]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	7q31.2	7	117277064	WNT2	WNT2			ENSG00000105989	NA	NA	rs4730775-?	rs4730775	0	4730775	3_prime_UTR_variant	0	0.59	3e-08	7.52287874528034		1.2	[1.14-1.30]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	8q23.1	8	108215779	RSPO2, EIF3E	EIF3E			ENSG00000104408	NA	NA	rs611744-?	rs611744	0	611744	intron_variant	0	0.6	8e-15	14.0969100130081		1.33	[1.23-1.43]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	8q13.2	8	69080145	SULF1, C8orf34	LINC01592			ENSG00000253658	NA	NA	rs2912522-?	rs2912522	0	2912522	intron_variant	0	0.8	2e-13	12.698970004336		1.39	[1.28-1.52]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	9p24.3	9	1202371	DMRT2, RP11-341G2.1	RPS27AP14 - AL358934.1	ENSG00000236594	ENSG00000233575		37504	126293	rs10809650-?	rs10809650	0	10809650	intergenic_variant	1	0.76	6e-09	8.22184874961636		1.25	[1.14-1.35]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	15q26.1	15	88702008	ISG20	ISG20 - AC103982.1	ENSG00000172183	ENSG00000259676		45525	95405	rs4932194-?	rs4932194	0	4932194	regulatory_region_variant	1	0.69	8e-07	6.09691001300806		1.22	[1.12-1.3]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	17q25.3	17	78885621	AC100788.1, TIMP2	TIMP2, CEP295NL			ENSG00000035862, ENSG00000178404	NA	NA	rs4789939-?	rs4789939	0	4789939	intron_variant	0	0.86	6e-07	6.22184874961636		1.22	[1.11-1.35]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	19q13.43	19	57166826	DUXA, ZNF264	DUXA			ENSG00000258873	NA	NA	rs11672517-A	rs11672517	0	11672517	intron_variant	0	0.28	7e-14	13.1549019599857		1.34	[1.25-1.45]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	20q12	20	40399796	AL049691.1, MAFB	AL009050.1 - MAFB	ENSG00000223410	ENSG00000204103		273439	286052	rs8124695-A	rs8124695	0	8124695	intergenic_variant	1	0.1	8e-10	9.09691001300806		1.48	[1.30-1.68]	Illumina [234939]	N
2012-03-03	21732829	Dolmans GH	2011-07-06	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/21732829	Wnt signaling and Dupuytren's disease.	Dupuytren's disease	856 European ancestry cases, 2,836 European ancestry controls	1,298 European ancestry cases, 7,136 European ancestry controls	22q13.31	22	46025962	RP11-398F12.1, WNT7B	BX537318.1 - LINC00899	ENSG00000273145	ENSG00000231711		10464	13945	rs6519955-A	rs6519955	0	6519955	regulatory_region_variant	1	0.47	3e-33	32.5228787452803		1.54	[1.44-1.65]	Illumina [234939]	N
2011-10-07	21912425	Tohkin M	2011-09-13	Pharmacogenomics J	www.ncbi.nlm.nih.gov/pubmed/21912425	A whole-genome association study of major determinants for allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients.	Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN)	14 Japanese ancestry cases, 991 Japanese ancestry controls	NA	6p21.33	6	31537703	PSORS1C1, PSORS1C3, BAT1, HLA-C, MICC, PPIAP9, POLR2LP, CCHCR1, TCF19, HLA-B*5801, HCP5, POU5F1	DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, DDX39B, ATP6V1G2-DDX39B			ENSG00000230624, ENSG00000198563, ENSG00000237889, ENSG00000235439, ENSG00000215425, ENSG00000229496, ENSG00000225073, ENSG00000225859, ENSG00000254870	NA	NA	rs2734583-?	rs2734583	0	2734583	intron_variant	0	0.0055	2e-08	7.69897000433602		66.8	[19.8-225.0]	Illumina [890321]	N
2012-03-17	22368281	Deshmukh HA	2012-02-24	J Lipid Res	www.ncbi.nlm.nih.gov/pubmed/22368281	Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).	Response to statin therapy	2,702 European ancestry individuals	2,550 European ancestry individuals	6q25.3	6	160589086	LPA	LPA			ENSG00000198670	NA	NA	rs10455872-A	rs10455872	0	10455872	intron_variant	0	NR	1e-09	9		0.28	[0.20-0.36] mmol/L decrease	Illumina, Perlegen [NR] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	21q22.11	21	34279939	KCNE2	AP000317.1, AP000317.2			ENSG00000214955, ENSG00000272657	NA	NA	rs9978142-T	rs9978142	0	9978142	intron_variant	0	0.16	3e-08	7.52287874528034	(FEV1/FVC)	0.043	[0.027-0.059] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	12p12.3	12	19713195	AEBP2	AEBP2			ENSG00000139154	NA	NA	rs4762767-G	rs4762767	0	4762767	intron_variant	0	NR	8e-06	5.09691001300806	(FEV1/FVC)	0.027	[0.015-0.039] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	1p36.13	1	16980180	MFAP2	MFAP2, AL049569.1			ENSG00000117122, ENSG00000226526	NA	NA	rs2284746-G	rs2284746	0	2284746	intron_variant	0	0.52	8e-16	15.0969100130081	(FEV1/FVC)	0.04	[0.030-0.050] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	12q13.3	12	57133500	LRP1	LRP1			ENSG00000123384	NA	NA	rs11172113-T	rs11172113	0	11172113	intron_variant	0	0.61	1e-08	8	(FEV1/FVC)	0.032	[0.020-0.044] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	1q41	1	218686726	TGFB2	U3 - NXNP1	ENSG00000202268	ENSG00000226693		144827	194874	rs993925-T	rs993925	0	993925	regulatory_region_variant	1	0.31	1e-08	8	(FEV1/FVC)	0.034	[0.022-0.046] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	12q23.1	12	95877650	CCDC38	CCDC38, SNRPF			ENSG00000165972, ENSG00000139343	NA	NA	rs1036429-T	rs1036429	0	1036429	intron_variant	0	0.20	2e-11	10.698970004336	(FEV1/FVC)	0.038	[0.026-0.050] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	2p24.3	2	15786044	DDX1	LINC01804 - AC113608.2	ENSG00000231031	ENSG00000237326		41705	15703	rs2544527-T	rs2544527	0	2544527	intergenic_variant	1	NR	9e-06	5.04575749056067	(FEV1/FVC)	0.026	[0.014-0.038] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	3p24.2	3	25479091	RARB	RARB			ENSG00000077092	NA	NA	rs1529672-C	rs1529672	0	1529672	intron_variant	0	0.83	4e-14	13.397940008672	(FEV1/FVC)	0.048	[0.036-0.060] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	10p13	10	12235993	CDC123	CDC123			ENSG00000151465	NA	NA	rs7068966-T	rs7068966	0	7068966	intron_variant	0	0.52	6e-13	12.2218487496164	(FEV1/FVC)	0.033	[0.023-0.043] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	2q37.3	2	238955452	HDAC4	LINC01940 - HDAC4	ENSG00000227744	ENSG00000068024		29183	92716	rs12477314-T	rs12477314	0	12477314	regulatory_region_variant	1	0.20	2e-12	11.698970004336	(FEV1/FVC)	0.041	[0.029-0.053] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	16q23.1	16	75356418	CFDP1	CFDP1			ENSG00000153774	NA	NA	rs2865531-T	rs2865531	0	2865531	intron_variant	0	0.42	2e-11	10.698970004336	(FEV1/FVC)	0.031	[0.021-0.041] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p21.33	6	31600692	NCR3	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		7686	10391	rs2857595-G	rs2857595	0	2857595	intergenic_variant	1	0.81	2e-10	9.69897000433602	(FEV1/FVC)	0.037	[0.025-0.049] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6q21	6	108946847	ARMC2	ARMC2			ENSG00000118690	NA	NA	rs2798641-T	rs2798641	0	2798641	intron_variant	0	0.18	8e-09	8.09691001300806	(FEV1/FVC)	0.041	[0.027-0.055] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	5q15	5	95700996	SPATA9	SPATA9 - AC008840.1	ENSG00000145757	ENSG00000250240		2285	253	rs153916-T	rs153916	0	153916	intergenic_variant	1	0.55	2e-08	7.69897000433602	(FEV1/FVC)	0.031	[0.021-0.041] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	16q21	16	58041378	MMP15	MMP15			ENSG00000102996	NA	NA	rs12447804-T	rs12447804	0	12447804	intron_variant	0	0.21	4e-08	7.39794000867204	(FEV1/FVC)	0.038	[0.024-0.052] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p22.3	6	22017509	AK026189	CASC15			ENSG00000272168	NA	NA	rs1928168-T	rs1928168	0	1928168	intron_variant	0	NR	2e-07	6.69897000433602	(FEV1/FVC)	0.028	[0.018-0.038] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	5q11.2	5	52899203	ITGA1	ITGA1			ENSG00000213949	NA	NA	rs1551943-G	rs1551943	0	1551943	intron_variant	0	NR	2e-06	5.69897000433602	(FEV1/FVC)	0.026	[0.014-0.038] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-16	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p21.32	6	32700133	HLA-DQB1	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		31750	5991	rs2647044-G	rs2647044	0	2647044	intergenic_variant	1	NR	6e-06	5.22184874961636	(FEV1/FVC)	0.044	[0.024-0.064] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	2q37.3	2	238440721	ASB1	ASB1			ENSG00000065802	NA	NA	rs3769124-G	rs3769124	0	3769124	intron_variant	0	NR	7e-08	7.15490195998574	(FEV1)	0.047	[0.029-0.065] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	15q25.1	15	78606381	CHRNA3	CHRNA3			ENSG00000080644	NA	NA	rs12914385-T	rs12914385	0	12914385	intron_variant	0	NR	5e-07	6.30102999566398	(FEV1)	0.025	[0.015-0.035] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	15q25.1	15	78559273	CHRNA5	PSMA4 - CHRNA5	ENSG00000041357	ENSG00000169684		6856	6247	rs2036527-G	rs2036527	0	2036527	regulatory_region_variant	1	NR	7e-07	6.15490195998574	(FEV1)	0.026	[0.016-0.036] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	2q37.3	2	238955452	HDAC4	LINC01940 - HDAC4	ENSG00000227744	ENSG00000068024		29183	92716	rs12477314-T	rs12477314	0	12477314	regulatory_region_variant	1	0.20	1e-07	7	(FEV1)	0.028	[0.018-0.038] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p22.1	6	29387425	OR12D2	OR5V1, OR5V1, OR5V1, OR5V1			ENSG00000227137, ENSG00000233046, ENSG00000243729, ENSG00000243441	NA	NA	rs3094548-G	rs3094548	0	3094548	intron_variant	0	NR	1e-07	7	(FEV1)	0.029	[0.019-0.039] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p21.33	6	31504943	MICB	MICB, MICB, MICB, MICB, MICB			ENSG00000204516, ENSG00000206449, ENSG00000234218, ENSG00000227772, ENSG00000231372	NA	NA	rs2855812-T	rs2855812	0	2855812	intron_variant	0	NR	2e-07	6.69897000433602	(FEV1)	0.03	[0.018-0.042] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	4q24	4	105127203	TET2	AC096577.1 - AC004069.1	ENSG00000248373	ENSG00000251259		7203	10077	rs1541374-T	rs1541374	0	1541374	intergenic_variant	1	NR	6e-07	6.22184874961636	(FEV1)	0.026	[0.016-0.036] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-11-04	22895189	Timmann C	2012-08-15	Nature	www.ncbi.nlm.nih.gov/pubmed/22895189	Genome-wide association study indicates two novel resistance loci for severe malaria.	Malaria	1,325 African ancestry, 828 African ancestry controls	2,229 African ancestry cases, 3,526 African ancestry controls	11p15.4	11	5496926	HBB	HBG2, HBE1, OR51B5, AC104389.5			ENSG00000196565, ENSG00000213931, ENSG00000167355, ENSG00000239920	NA	NA	rs372091-C	rs372091	0	372091	intron_variant	0	0.972	6e-14	13.2218487496164		2.17	[NR]	Affymetrix [4205739] (imputed)	N
2012-11-04	22895189	Timmann C	2012-08-15	Nature	www.ncbi.nlm.nih.gov/pubmed/22895189	Genome-wide association study indicates two novel resistance loci for severe malaria.	Malaria	1,325 African ancestry, 828 African ancestry controls	2,229 African ancestry cases, 3,526 African ancestry controls	1q32.1	1	203684896	ATP2B4	ATP2B4			ENSG00000058668	NA	NA	rs10900585-T	rs10900585	0	10900585	intron_variant	0	0.62	2e-10	9.69897000433602		1.64	[NR]	Affymetrix [4205739] (imputed)	N
2012-11-04	22895189	Timmann C	2012-08-15	Nature	www.ncbi.nlm.nih.gov/pubmed/22895189	Genome-wide association study indicates two novel resistance loci for severe malaria.	Malaria	1,325 African ancestry, 828 African ancestry controls	2,229 African ancestry cases, 3,526 African ancestry controls	9q34.2	9	133257522	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs8176719-G	rs8176719	0	8176719	frameshift_variant	0	0.37	4e-21	20.397940008672		1.48	[NR]	Affymetrix [4205739] (imputed)	N
2012-11-04	22895189	Timmann C	2012-08-15	Nature	www.ncbi.nlm.nih.gov/pubmed/22895189	Genome-wide association study indicates two novel resistance loci for severe malaria.	Malaria	1,325 African ancestry, 828 African ancestry controls	2,229 African ancestry cases, 3,526 African ancestry controls	16q22.2	16	71619734	MARVELD3	TAT-AS1 - AC009097.2	ENSG00000260886	ENSG00000260593		41547	3974	rs2334880-C	rs2334880	0	2334880	intergenic_variant	1	0.45	2e-06	5.69897000433602		1.19	[NR]	Affymetrix [4205739] (imputed)	N
2011-09-30	21876539	Amin N	2011-08-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21876539	Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.	Coffee consumption	18,176 European ancestry individuals	7,929 European ancestry individuals	15q24.1	15	74727108	CYP1A1, CYP1A2	CYP1A1 - CYP1A2	ENSG00000140465	ENSG00000140505		1572	21737	rs2470893-T	rs2470893	0	2470893	regulatory_region_variant	1	NR	2e-11	10.698970004336		0.0675	[0.05-0.09] unit increase	Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)	N
2011-09-30	21876539	Amin N	2011-08-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21876539	Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.	Coffee consumption	18,176 European ancestry individuals	7,929 European ancestry individuals	15q24.1	15	74833304	CPLX3, ULK3	CPLX3 - ULK3	ENSG00000213578	ENSG00000140474		1502	2814	rs6495122-A	rs6495122	0	6495122	regulatory_region_variant	1	NR	7e-09	8.15490195998574		0.05	[0.03-0.07] unit decrease	Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)	N
2011-09-30	21876539	Amin N	2011-08-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21876539	Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.	Coffee consumption	18,176 European ancestry individuals	7,929 European ancestry individuals	8q22.3	8	102040149	NCALD	NCALD			ENSG00000104490	NA	NA	rs16868941-A	rs16868941	0	16868941	intron_variant	0	NR	8e-07	6.09691001300806		0.056	[0.04-0.08] unit increase	Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)	N
2011-09-30	21876539	Amin N	2011-08-30	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21876539	Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.	Coffee consumption	18,176 European ancestry individuals	7,929 European ancestry individuals	7q31.1	7	108141755	LAMB4, NRCAM	LAMB4 - NRCAM	ENSG00000091128	ENSG00000091129		11394	5868	rs382140-A	rs382140	0	382140	intergenic_variant	1	NR	4e-09	8.39794000867204		0.079	[0.05-0.11] unit increase	Affymetrix, Illumina, Perlegen [~ 2600000] (imputed)	N
2012-08-14	22685421	Fan Q	2012-06-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22685421	Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.	Myopia (pathological)	2,789 Chinese ancestry individuals, 2,155 Malay ancestry individuals	NA	2p16.2	2	54491044	SPTBN1	SPTBN1			ENSG00000115306	NA	NA	rs4557020-T	rs4557020	0	4557020	intron_variant	0	0.37	3e-07	6.52287874528034		0.12	[0.081-0.159] mm decrease	Illumina [456634]	N
2012-08-14	22685421	Fan Q	2012-06-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22685421	Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.	Myopia (pathological)	2,789 Chinese ancestry individuals, 2,155 Malay ancestry individuals	NA	5q11.1	5	50730631	PARP8	PARP8			ENSG00000151883	NA	NA	rs282544-C	rs282544	0	282544	intron_variant	0	0.35	4e-06	5.39794000867204		0.1	[0.061-0.139] mm decrease	Illumina [456634]	N
2012-08-14	22685421	Fan Q	2012-06-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22685421	Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.	Myopia (pathological)	2,789 Chinese ancestry individuals, 2,155 Malay ancestry individuals	NA	2p13.1	2	74712049	SEMA4F	SEMA4F - AC007387.3	ENSG00000135622	ENSG00000287687		28196	38124	rs1137-C	rs1137	0	1137	intergenic_variant	1	0.16	4e-06	5.39794000867204		0.12	[0.061-0.179] mm increase	Illumina [456634]	N
2012-08-14	22685421	Fan Q	2012-06-07	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22685421	Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.	Myopia (pathological)	2,789 Chinese ancestry individuals, 2,155 Malay ancestry individuals	NA	13q12.12	13	22719894	ZC3H11B	DDX39AP1 - SNORD36	ENSG00000225777	ENSG00000253094		13688	83251	rs4373767-C	rs373767	0	373767	intergenic_variant	1	0.30	3e-10	9.52287874528034		0.16	[0.12-0.20] mm decrease	Illumina [456634]	N
2011-10-04	21931568	Geller F	2011-09-08	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21931568	Genome-wide association study identifies four loci associated with eruption of permanent teeth.	Permanent tooth development	5,088 European ancestry females	2,994 European ancestry individuals, 161 individuals	10q22.2	10	74536031	ADK	ADK			ENSG00000156110	NA	NA	rs7924176-G	rs7924176	0	7924176	intron_variant	0	0.43	6e-18	17.2218487496164		0.105	[0.08-0.13] unit decrease	Illumina [521741]	N
2011-10-04	21931568	Geller F	2011-09-08	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21931568	Genome-wide association study identifies four loci associated with eruption of permanent teeth.	Permanent tooth development	5,088 European ancestry females	2,994 European ancestry individuals, 161 individuals	12q14.3	12	65970729	HMGA2	HMGA2 - MIR6074	ENSG00000149948	ENSG00000276878		4434	52891	rs12424086-C	rs12424086	0	12424086	intergenic_variant	1	0.18	2e-12	11.698970004336		0.111	[0.08-0.14] unit decrease	Illumina [521741]	N
2011-10-04	21931568	Geller F	2011-09-08	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21931568	Genome-wide association study identifies four loci associated with eruption of permanent teeth.	Permanent tooth development	5,088 European ancestry females	2,994 European ancestry individuals, 161 individuals	2q35	2	217030033	TNP1	AC007749.1 - AC007749.2	ENSG00000259855	ENSG00000287498		33543	31034	rs4491709-T	rs4491709	0	4491709	intergenic_variant	1	0.71	2e-14	13.698970004336		0.102	[0.07-0.13] unit decrease	Illumina [521741]	N
2011-10-04	21931568	Geller F	2011-09-08	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21931568	Genome-wide association study identifies four loci associated with eruption of permanent teeth.	Permanent tooth development	5,088 European ancestry females	2,994 European ancestry individuals, 161 individuals	1q32.1	1	201112815	CACNA1S	CACNA1S - ASCL5	ENSG00000081248	ENSG00000232237		364	1138	rs2281845-T	rs2281845	0	2281845	intergenic_variant	1	0.38	8e-17	16.0969100130081		0.103	[0.08-0.12] unit decrease	Illumina [521741]	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		6p25.3	6	577820	NR	EXOC2			ENSG00000112685	NA	NA	rs9504361-G	rs9504361	0	9504361	intron_variant	0	0.4504	6e-06	5.22184874961636		1.156	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		22q12.3	22	36803762	NR	PVALB, PVALB			ENSG00000274665, ENSG00000100362	NA	NA	rs2022068-A	rs2022068	0	2022068	intron_variant	0	0.3926	7e-06	5.15490195998574		1.1831	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		Xp11.4	X	40026377	BCOR	AC092198.1 - BCOR	ENSG00000223486	ENSG00000183337		14195	23438	rs17145638-C	rs17145638	0	17145638	intergenic_variant	1	0.1169	2e-07	6.69897000433602		2.329	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		7p14.1	7	41772310	INHBA-AS1, INHBA	INHBA-AS1			ENSG00000224116	NA	NA	rs10486722-C	rs10486722	0	10486722	intron_variant	0	0.3349	7e-06	5.15490195998574		1.215	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		3p14.2	3	60016099	NR	FHIT			ENSG00000189283	NA	NA	rs9311745-C	rs9311745	0	9311745	intron_variant	0	0.0466	5e-06	5.30102999566398		2.9914	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		9q21.11	9	68856996	NR	PIP5K1B			ENSG00000107242	NA	NA	rs6560397-T	rs6560397	0	6560397	intron_variant	0	0.4671	2e-07	6.69897000433602		1.289	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		8q21.3	8	89198871	intergenic	AC090578.1 - RPSAP74	ENSG00000253553	ENSG00000253621		311298	44530	rs2046315-T	rs2046315	0	2046315	intergenic_variant	1	0.1322	7e-07	6.15490195998574		1.871	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Pit-and-Fissure caries	996 European ancestry individuals		3q21.3	3	128563854	NR	AC080005.1			ENSG00000286806	NA	NA	rs6806253-A	rs6806253	0	6806253	non_coding_transcript_exon_variant	0	0.8295	6e-06	5.22184874961636		1.5595	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	4p15.32	4	16020917	NR	PROM1			ENSG00000007062	NA	NA	rs2677780-A	rs2677780	0	2677780	intron_variant	0	0.9356	2e-06	5.69897000433602		6.3471	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	20q13.11	20	43362961	NR	AL021395.2 - AL031681.1	ENSG00000252193	ENSG00000237555		58282	25681	rs2010809-C	rs2010809	0	2010809	intergenic_variant	1	0.9883	2e-06	5.69897000433602		14.0668	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	11q14.1	11	81524108	NR	AP003464.1 - MTND4LP18	ENSG00000287912	ENSG00000254747		92588	28118	rs2032381-G	rs2032381	0	2032381	intergenic_variant	1	0.9212	4e-06	5.39794000867204		5.6947	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	8q21.3	8	89198871	intergenic	AC090578.1 - RPSAP74	ENSG00000253553	ENSG00000253621		311298	44530	rs2046315-T	rs2046315	0	2046315	intergenic_variant	1	0.1322	8e-08	7.09691001300806		5.187	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	9q22.33	9	99472041	NR	STX17-AS1, AL359710.1			ENSG00000255145, ENSG00000237461	NA	NA	rs649057-T	rs649057	0	649057	intron_variant	0	0.05057	8e-06	5.09691001300806		6.806	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	11q25	11	133251042	NR	OPCML			ENSG00000183715	NA	NA	rs2078454-A	rs2078454	0	2078454	intron_variant	0	0.2094	6e-06	5.22184874961636		3.603	[NR] unit decrease	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	4q31.22	4	145954399	NR	ZNF827 - Y_RNA	ENSG00000151612	ENSG00000265852		15576	3729	rs723794-G	rs723794	0	723794	regulatory_region_variant	1	0.2686	6e-07	6.22184874961636		3.645	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	5q35.1	5	170813419	NR	GABRP			ENSG00000094755	NA	NA	rs11134654-A	rs11134654	0	11134654	3_prime_UTR_variant	0	0.1735	2e-07	6.69897000433602		4.6139	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	2q35	2	218265791	CXCR2, AAMP, CXCR1	AAMP			ENSG00000127837	NA	NA	rs1079204-A	rs1079204	0	1079204	non_coding_transcript_exon_variant	0	0.0378	2e-06	5.69897000433602		8.4526	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	8q21.3	8	88981259	NR	AC090578.1 - RPSAP74	ENSG00000253553	ENSG00000253621		93686	262142	rs10429371-C	rs10429371	0	10429371	intergenic_variant	1	.2142	3e-06	5.52287874528034		3.8	[NR] unit increase	Illumina [1200000] (imputed)	N
2013-06-21	23470693	Zeng Z	2013-03-07	J Dent Res	www.ncbi.nlm.nih.gov/pubmed/23470693	Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.	Smooth-surface caries	982 European ancestry individuals	NA	1q32.2	1	210724921	NR	KCNH1			ENSG00000143473	NA	NA	rs1934620-A	rs1934620	0	1934620	intron_variant	0	.8656	8e-06	5.09691001300806		4.2462	[NR] unit decrease	Illumina [1200000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	6q22.31	6	118252898	SLC35F1	SLC35F1			ENSG00000196376	NA	NA	rs281868-G	rs281868	0	281868	intron_variant	0	0.50	4e-10	9.39794000867204		6.3	[4.36-8.24] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	7q22.1	7	100855586	SLC12A9	SLC12A9			ENSG00000146828	NA	NA	rs314370-C	rs314370	0	314370	non_coding_transcript_exon_variant	0	0.19	6e-10	9.22184874961636		7.6	[5.23-9.97] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	7q22.1	7	100889133	UFSP1	UFSP1			ENSG00000176125	NA	NA	rs12666989-C	rs12666989	0	12666989	missense_variant	0	0.18	2e-08	7.69897000433602		7	[4.63-9.37] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	11q12.2	11	61803311	FADS1	FADS2, FADS1			ENSG00000134824, ENSG00000149485	NA	NA	rs174547-C	rs174547	0	174547	intron_variant	0	0.33	2e-09	8.69897000433602		6.2	[4.22-8.18] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	1q32.2	1	207955377	CD34	AL356275.1 - LINC02767	ENSG00000285719	ENSG00000284237		38289	3915	rs2745967-G	rs2745967	0	2745967	intergenic_variant	1	0.37	7e-08	7.15490195998574		5.4	[3.48-7.32] ms increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	14q11.2	14	23396676	MYH6	MYH6			ENSG00000197616	NA	NA	rs452036-A	rs452036	0	452036	intron_variant	0	0.36	4e-14	13.397940008672		7.8	[5.84-9.76] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	12p12.1	12	24617944	intergenic	KNOP1P1 - AC087312.1	ENSG00000256852	ENSG00000244662		33395	24743	rs17287293-G	rs17287293	0	17287293	intergenic_variant	1	0.15	2e-10	9.69897000433602		8.6	[6.03-11.17] ms increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	6q22.31	6	121824888	GJA1	AL603865.1 - HMGB3P18	ENSG00000217139	ENSG00000220184		140616	33291	rs9398652-A	rs9398652	0	9398652	intergenic_variant	1	0.10	4e-15	14.397940008672		12.6	[9.54-15.66] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	14q11.2	14	23507801	MYH7, NDNG	NGDN			ENSG00000129460	NA	NA	rs223116-A	rs223116	0	223116	intron_variant	0	0.24	3e-08	7.52287874528034		7.4	[4.85-9.95] ms decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2010-09-02	20639392	Eijgelsheim M	2010-07-16	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20639392	Genome-wide association analysis identifies multiple loci related to resting heart rate.	Resting heart rate	38,991 European ancestry individuals	NA	6q22.31	6	121427396	GJA1	AL139098.2 - GJA1	ENSG00000272714	ENSG00000152661		37039	8199	rs11154022-A	rs11154022	0	11154022	intergenic_variant	1	0.33	7e-08	7.15490195998574		5.8	[3.74-7.86] ms increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	1q21.3	1	153796924	LOC343052	AL513523.2, GATAD2B			ENSG00000231827, ENSG00000143614	NA	NA	rs9426935-C	rs9426935	0	9426935	intron_variant	0	0.49	5e-06	5.30102999566398		96.63	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	19q12	19	29245435	intergenic	RN7SL340P - AC007786.4	ENSG00000241604	ENSG00000287272		12050	23541	rs11083866-A	rs11083866	0	11083866	intergenic_variant	1	0.26	5e-06	5.30102999566398		114.77	[NR] unit increase	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	1q24.3	1	171122735	FMO3, FMO6P	BX284613.2			ENSG00000231424	NA	NA	rs1795240-A	rs1795240	0	1795240	intron_variant	0	0.43	5e-08	7.30102999566398		112.27	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	20q13.33	20	60323151	intergenic	MIR646HG			ENSG00000228340	NA	NA	rs6027511-C	rs6027511	0	6027511	non_coding_transcript_exon_variant	0	0.17	9e-06	5.04575749056067		122.24	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	2q14.3	2	122383969	intergenic	AC011246.1			ENSG00000286481	NA	NA	rs4848768-G	rs4848768	0	4848768	intron_variant	0	0.11	6e-06	5.22184874961636		154.6	[NR] unit increase	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	6q23.2	6	130961070	EPB41L2	EPB41L2			ENSG00000079819	NA	NA	rs6941712-C	rs6941712	0	6941712	intron_variant	0	0.13	5e-06	5.30102999566398		149.67	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	1q21.3	1	153941294	DENND4B	DENND4B			ENSG00000198837	NA	NA	rs2252508-G	rs2252508	0	2252508	splice_region_variant	0	0.47	5e-06	5.30102999566398		97.78	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	2q14.3	2	122368903	intergenic	AC011246.1			ENSG00000286481	NA	NA	rs10496584-G	rs10496584	0	10496584	intron_variant	0	0.11	4e-06	5.39794000867204		158.69	[NR] unit increase	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	11q14.1	11	80666008	intergenic	ARL6IP1P3 - LINC02720	ENSG00000255014	ENSG00000255178		12020	85192	rs17140547-T	rs17140547	0	17140547	intergenic_variant	1	0.02	8e-06	5.09691001300806		532.56	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	1q21.3	1	153966654	SLC39A1	AL358472.3, SLC39A1, AL358472.7			ENSG00000273026, ENSG00000143570, ENSG00000285779	NA	NA	rs11264736-T	rs11264736	0	11264736	non_coding_transcript_exon_variant	0	0.47	4e-06	5.39794000867204		98.69	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	2q14.3	2	122379314	intergenic	AC011246.1			ENSG00000286481	NA	NA	rs1919922-T	rs1919922	0	1919922	intron_variant	0	0.11	5e-06	5.30102999566398		155.52	[NR] unit increase	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	1q23.3	1	165478920	LOC400794	LRRC52-AS1			ENSG00000237463	NA	NA	rs10918196-C	rs10918196	0	10918196	intron_variant	0	0.41	9e-06	5.04575749056067		93.94	[NR] unit increase	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	1q21.3	1	153876520	GATAD2B	GATAD2B			ENSG00000143614	NA	NA	rs7414227-G	rs7414227	0	7414227	intron_variant	0	0.49	3e-06	5.52287874528034		99.5	[NR] unit decrease	Illumina [2380200] (imputed)	N
2012-10-12	22903471	Hibar DP	2012-08-18	Brain Imaging Behav	www.ncbi.nlm.nih.gov/pubmed/22903471	Genome-wide association identifies genetic variants associated with lentiform nucleus volume in N = 1345 young and elderly subjects.	Lentiform nucleus volume	162 European ancestry Alzheimer's disease cases, 346 European ancestry mild cognitive impairment cases, 198 European ancestry controls, 639 European ancestry individuals from 364 families	NA	2q14.3	2	122370213	intergenic	AC011246.1			ENSG00000286481	NA	NA	rs2037892-A	rs2037892	0	2037892	intron_variant	0	0.11	5e-06	5.30102999566398		156.7	[NR] unit increase	Illumina [2380200] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases				APOE					NA	NA	APOE-E4	APOE	0	NA		1	0.19	2e-33	32.698970004336	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	2p22.3	2	32640454	TTC27	TTC27			ENSG00000018699	NA	NA	rs1031261-C	rs1031261	0	1031261	intron_variant	0	0.11	2e-06	5.69897000433602	(White matter hyperintensities)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	2q31.1	2	171271410	METTL8	TLK1 - METTL8	ENSG00000198586	ENSG00000123600		40096	45995	rs4667682-C	rs4667682	0	4667682	regulatory_region_variant	1	0.82	5e-06	5.30102999566398	(White matter hyperintensities)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	20q12	20	41435919	CHD6	CHD6			ENSG00000124177	NA	NA	rs13037749-A	rs13037749	0	13037749	intron_variant	0	0.92	8e-06	5.09691001300806	(White matter hyperintensities)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	1p32.3	1	53115998	SLC1A7	SLC1A7, AL445183.2			ENSG00000162383, ENSG00000235563	NA	NA	rs3820201-A	rs3820201	0	3820201	non_coding_transcript_exon_variant	0	0.62	1e-06	6	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	1q24.2	1	169581725	SELP, F5	F5			ENSG00000198734	NA	NA	rs6703865-A	rs6703865	0	6703865	intron_variant	0	0.08	1e-09	9	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	2p12	2	75699439	GCFC2	GCFC2			ENSG00000005436	NA	NA	rs2298948-C	rs2298948	0	2298948	intron_variant	0	0.29	5e-08	7.30102999566398	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	8q22.2	8	99822954	intergenic	VPS13B			ENSG00000132549	NA	NA	rs959695-C	rs959695	0	959695	intron_variant	0	0.18	1e-06	6	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	9q21.32	9	81757826	TLE1	AL591368.1			ENSG00000233926	NA	NA	rs11139399-C	rs11139399	0	11139399	intron_variant	0	0.41	1e-06	6	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	13q14.11	13	39543931	LHFP	LHFPL6			ENSG00000183722	NA	NA	rs9315702-A	rs9315702	0	9315702	intron_variant	0	0.44	2e-08	7.69897000433602	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases				APOE					NA	NA	APOE-E4	APOE	0	NA		1	0.19	1e-07	7	(Total cerebral volume)	NA		Illumina [2131250] (imputed)	N
2012-07-31	22745009	Melville SA	2012-05-15	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22745009	Multiple loci influencing hippocampal degeneration identified by genome scan.	Hippocampal atrophy	1149 European ancestry Alzheimer disease cases, 336 European ancestry individuals with mild cognitive impairment, 188 European ancestry controls	419 African American Alzheimer disease cases	21q22.3	21	45427029	COL18A1	COL18A1			ENSG00000182871	NA	NA	rs2838923-A	rs2838923	0	2838923	intron_variant	0	0.73	8e-07	6.09691001300806	(Hippocampal volume)	NA		Illumina [2131250] (imputed)	N
2012-08-14	22726844	Kim JW	2012-06-20	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22726844	A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval.	QT interval	6,805 Korean ancestry individuals	7,373 East Asian ancestry individuals	2p22.1	2	40530651	SLC8A1	SLC8A1			ENSG00000183023	NA	NA	rs13017846-G	rs13017846	0	13017846	intron_variant	0	0.42	8e-14	13.0969100130081		0.069	[0.038-0.100] unit decrease	Affymetrix [352228]	N
2012-08-14	22726844	Kim JW	2012-06-20	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22726844	A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval.	QT interval	6,805 Korean ancestry individuals	7,373 East Asian ancestry individuals	1q23.3	1	162225948	NOS1AP	NOS1AP			ENSG00000198929	NA	NA	rs4657175-?	rs4657175	0	4657175	intron_variant	0	NR	1e-09	9		1.709	[1.156-2.261] ms increase	Affymetrix [352228]	N
2012-08-14	22726844	Kim JW	2012-06-20	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22726844	A common variant in SLC8A1 is associated with the duration of the electrocardiographic QT interval.	QT interval	6,805 Korean ancestry individuals	7,373 East Asian ancestry individuals	16q21	16	58532400	NDRG4, CNOT1	CNOT1			ENSG00000125107	NA	NA	rs37060-?	rs37060	0	37060	splice_region_variant	0	NR	1e-07	7		1.52	[0.957-2.084] ms increase	Affymetrix [352228]	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p21.33	6	31600692	NCR3	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		7686	10391	rs2857595-G	rs2857595	0	2857595	intergenic_variant	1	0.81	1e-06	6	(FEV1)	0.025	[0.02-0.04] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	10p13	10	12235993	CDC123	CDC123			ENSG00000151465	NA	NA	rs7068966-T	rs7068966	0	7068966	intron_variant	0	0.52	3e-12	11.5228787452803	(FEV1)	0.029	[0.021-0.037] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	10q22.3	10	76555466	C10orf11	LRMDA			ENSG00000148655	NA	NA	rs11001819-G	rs11001819	0	11001819	intron_variant	0	0.52	3e-12	11.5228787452803	(FEV1)	0.029	[0.021-0.037] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6p22.1	6	28354519	ZKSCAN3, ZNF323	ZKSCAN3, ZSCAN31			ENSG00000189298, ENSG00000235109	NA	NA	rs6903823-G	rs6903823	0	6903823	intron_variant	0	0.21	2e-10	9.69897000433602	(FEV1)	0.037	[0.025-0.049] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	3q26.2	3	169582431	MECOM	MECOM			ENSG00000085276	NA	NA	rs1344555-T	rs1344555	0	1344555	intron_variant	0	0.21	3e-08	7.52287874528034	(FEV1)	0.034	[0.022-0.046] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	16q23.1	16	78154841	WWOX	WWOX			ENSG00000186153	NA	NA	rs12716852-G	rs12716852	0	12716852	intron_variant	0	NR	2e-07	6.69897000433602	(FEV1)	0.025	[0.015-0.035] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	3p22.3	3	32887623	TRIM71	TRIM71			ENSG00000206557	NA	NA	rs9310995-T	rs9310995	0	9310995	intron_variant	0	NR	4e-06	5.39794000867204	(FEV1)	0.023	[0.013-0.033] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6q25.1	6	150249731	PPP1R14C	PPP1R14C			ENSG00000198729	NA	NA	rs3734729-G	rs3734729	0	3734729	3_prime_UTR_variant	0	NR	4e-06	5.39794000867204	(FEV1)	0.055	[0.031-0.079] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-10-18	21946350	Soler Artigas M	2011-09-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21946350	Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.	Pulmonary function	48,201 European ancestry individuals	46,411 European ancestry individuals	6q21	6	108946847	ARMC2	ARMC2			ENSG00000118690	NA	NA	rs2798641-T	rs2798641	0	2798641	intron_variant	0	0.18	5e-06	5.30102999566398	(FEV1)	0.03	[0.018-0.042] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	14q24.1	14;14;14;14;14;14	68497029;68506829;68507560;68505059;68500665;68508657		RAD51B; RAD51B; RAD51B; RAD51B; RAD51B; RAD51B				NA	NA	rs765899-?; rs757369-?; rs10132579-?; rs2842347-?; rs737387-?; rs2842346-?	rs765899; rs757369; rs10132579; rs2842347; rs737387; rs2842346	0	NA	intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	2e-06	5.69897000433602		1.67	[1.35-2.08]	Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	4q27	4;4	121200339;121205653	TNIP3	TNIP3; TNIP3				NA	NA	rs17435444-A; rs13116936-G	rs17435444; rs13116936	0	NA	intron_variant; intron_variant	NA	0.64	3e-07	6.52287874528034		1.23	[1.13-1.33]	Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	1p36.23	1;1;1;1;1	8335381;8335500;8326670;8334176;8330828	SLC45A1	SLC45A1; SLC45A1; SLC45A1; SLC45A1; SLC45A1				NA	NA	rs2305016-?; rs7535752-?; rs9628987-?; rs12711517-?; rs2289731-?	rs2305016; rs7535752; rs9628987; rs12711517; rs2289731	0	NA	intron_variant; missense_variant; intron_variant; intron_variant; synonymous_variant	NA	NR	5e-06	5.30102999566398		1.23	[1.12-1.35]	Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	10p15.1	10;10;10	5630056;5628312;5623811		LINC02657; LINC02677; LINC02657; LINC02677; LINC02657; LINC02677				NA	NA	rs4414128-?; rs2386661-?; rs17141741-?	rs4414128; rs2386661; rs17141741	0	NA	intron_variant; intron_variant; intron_variant	NA	NR	5e-06	5.30102999566398		1.27	[1.14-1.39]	Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	10q22.3	10	79295869		ZMIZ1			ENSG00000108175	NA	NA	rs12355688-T	rs12355688	0	12355688	non_coding_transcript_exon_variant	0	0.22	6e-06	5.22184874961636		1.24	[1.13-1.36]	Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	1p36.23	1;1	8326670;8335500		SLC45A1; SLC45A1				NA	NA	rs9628987-?; rs7535752-?	rs9628987; rs7535752	0	NA	intron_variant; missense_variant	NA	NR	5e-06	5.30102999566398		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	3p26.1	3;3	7220327;7242282		GRM7; GRM7; AC066585.1				NA	NA	rs6797852-?; rs1810320-?	rs6797852; rs1810320	0	NA	intron_variant; non_coding_transcript_exon_variant	NA	NR	3e-06	5.52287874528034		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	4q27	4;4	121185138;121205653		TNIP3; TNIP3				NA	NA	rs17051310-?; rs13116936-?	rs17051310; rs13116936	0	NA	intron_variant; intron_variant	NA	NR	2e-06	5.69897000433602		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	4q27	4;4	121215608;121189820		TNIP3; TNIP3				NA	NA	rs4455437-?; rs921551-?	rs4455437; rs921551	0	NA	intron_variant; intron_variant	NA	NR	2e-06	5.69897000433602		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	4q27	4;4	121222509;121200339		TNIP3; TNIP3				NA	NA	rs6835704-?; rs17435444-?	rs6835704; rs17435444	0	NA	intron_variant; intron_variant	NA	NR	2e-06	5.69897000433602		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	5p15.32	5;5	5320143;5324870		ADAMTS16; ADAMTS16 - ALG3P1				NA	NA	rs3806872-?; rs16875333-?	rs3806872; rs16875333	0	NA	3_prime_UTR_variant; intergenic_variant	NA	NR	3e-06	5.52287874528034		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	12q22	12;12	94138989;94149730		RN7SKP263 - AC123567.1; PLXNC1				NA	NA	rs11613298-?; rs2230754-?	rs11613298; rs2230754	0	NA	regulatory_region_variant; synonymous_variant	NA	NR	5e-06	5.30102999566398		NA		Illumina [1006480]	N
2013-06-06	23468962	Song C	2013-02-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23468962	A genome-wide scan for breast cancer risk haplotypes among African American women.	Breast cancer	3,016 African American cases, 2,745 African American controls	NA	17q23.2	17;17	61319088;61314018		BCAS3; BCAS3				NA	NA	rs10853029-?; rs3785856-?	rs10853029; rs3785856	0	NA	intron_variant; intron_variant	NA	NR	8e-06	5.09691001300806	(Haplotype-?????)	NA		Illumina [1006480]	N
2011-09-27	21866343	Ahn MJ	2011-08-25	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/21866343	The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations.	Non-small cell lung cancer	445 Korean ancestry cases, 497 Korean ancestry controls	396 Korean ancestry cases, 998 Korean ancestry controls	18p11.22	18	10899030	APCDD1, NAPG, FAM38B	AP005120.1, PIEZO2			ENSG00000263952, ENSG00000154864	NA	NA	rs11080466-C	rs11080466	0	11080466	intron_variant	0	NR	1e-06	6		1.47	[1.27-1.72]	Affymetrix [474503]	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	3q26.2	3	169432844	MECOM	MECOM			ENSG00000085276	NA	NA	rs16853722-C	rs16853722	0	16853722	intron_variant	0	0.29	3e-14	13.5228787452803		0.0064	[0.0048-0.0080] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	1q22	1	155225189	MTX1, GBA	GBAP1			ENSG00000160766	NA	NA	rs2049805-T	rs2049805	0	2049805	intron_variant	0	0.17	2e-12	11.698970004336		0.0072	[0.0052-0.0092] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	2q14.1	2	113221363	PAX8	PAX8-AS1, PAX8			ENSG00000189223, ENSG00000125618	NA	NA	rs11123170-G	rs11123170	0	11123170	intron_variant	0	0.35	3e-10	9.52287874528034		0.0051	[0.0035-0.0067] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	15q21.3	15	53615751	WDR72	WDR72			ENSG00000166415	NA	NA	rs17730281-G	rs17730281	0	17730281	missense_variant	0	0.58	3e-11	10.5228787452803		0.0051	[0.0035-0.0067] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	17q23.2	17	61161860	BCAS3	BCAS3			ENSG00000141376	NA	NA	rs11868441-G	rs11868441	0	11868441	intron_variant	0	0.75	2e-09	8.69897000433602		0.0059	[0.0039-0.0079] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	20q13.32	20	58894018	GNAS	GNAS			ENSG00000087460	NA	NA	rs6026584-T	rs6026584	0	6026584	intron_variant	0	0.32	9e-09	8.04575749056067		0.0052	[0.0034-0.0070] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	7p22.3	7	1234209	UNCX	UNCX			ENSG00000164853	NA	NA	rs10275044-T	rs10275044	0	10275044	intron_variant	0	0.34	4e-09	8.39794000867204		0.0069	[0.0046-0.0093] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	11p14.1	11	30747131	DCDC5, MPPED2l	MPPED2-AS1 - AL122014.1	ENSG00000254489	ENSG00000287373		114548	26782	rs10767873-C	rs10767873	0	10767873	intergenic_variant	1	0.69	5e-16	15.301029995664		0.0068	[0.0052-0.0084] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	12q24.13	12	112207597	C12orf51	HECTD4			ENSG00000173064	NA	NA	rs2074356-A	rs2074356	0	2074356	intron_variant	0	0.23	2e-09	8.69897000433602		0.0064	[0.0042-0.0086] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	3p14.1	3	66748526	LRIG1, KBTBD8	RPL21P41 - AC098969.2	ENSG00000214560	ENSG00000288039		111114	31550	rs13069000-G	rs13069000	0	13069000	regulatory_region_variant	1	0.17	1e-19	19		0.0093	[0.0073-0.0113] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	3q27.3	3	187995930	BCL6, LPP	LINC01991 - AC092941.1	ENSG00000224187	ENSG00000225058		19523	1492	rs10937329-T	rs10937329	0	10937329	regulatory_region_variant	1	0.69	9e-30	29.0457574905607		0.01	[0.0082-0.0118] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	5q13.2	5	73136209	TMEM171, TMEM174	AC116345.3			ENSG00000251599	NA	NA	rs17663555-G	rs17663555	0	17663555	intron_variant	0	0.34	2e-06	5.69897000433602		0.004	[0.0024-0.0056] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	6p12.3	6	50818295	TFAP2B	TFAP2D - TFAP2B	ENSG00000008197	ENSG00000008196		45307	428	rs2206271-A	rs2206271	0	2206271	regulatory_region_variant	1	0.32	2e-07	6.69897000433602		0.0055	[0.0035-0.0075] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	6q22.33	6	127114919	RSPO3	AL356534.1			ENSG00000286215	NA	NA	rs1936800-T	rs1936800	0	1936800	intron_variant	0	0.50	1e-11	11		0.0052	[0.0036-0.0068] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (BUN)	39,717 East Asian ancestry individuals	17,461 East Asian ancestry individuals	18q12.3	18	45607165	SLC14A2	AC091151.5, SLC14A2, AC023421.2			ENSG00000287943, ENSG00000132874, ENSG00000267193	NA	NA	rs7227483-G	rs7227483	0	7227483	intron_variant	0	0.80	7e-18	17.1549019599857		0.0083	[0.0063-0.0103] mg/dl increase	Affymetrix, Illumina [2281523] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	11p14.1	11	30727543	DCDC5, MPPED2	MPPED2-AS1 - AL122014.1	ENSG00000254489	ENSG00000287373		94960	46370	rs963837-T	rs963837	0	963837	intergenic_variant	1	0.64	3e-09	8.52287874528034		0.0037	[0.0025-0.0049] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	6p21.33	6	31472892	MHC	HCP5			ENSG00000206337	NA	NA	rs3828890-G	rs3828890	0	3828890	intron_variant	0	0.11	3e-09	8.52287874528034		0.0069	[0.0046-0.0092] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	7p22.3	7	1245559	UNCX	UNCX - AC073094.1	ENSG00000164853	ENSG00000233082		8233	21794	rs10277115-T	rs10277115	0	10277115	regulatory_region_variant	1	0.35	5e-11	10.301029995664		0.0052	[0.0036-0.0068] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	12q24.12	12	111803962	ALDH2	ALDH2			ENSG00000111275	NA	NA	rs671-A	rs671	0	671	missense_variant	0	0.27	3e-10	9.52287874528034		0.0045	[0.0031-0.0059] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	4q21.1	4	76490987	SHROOM3	SHROOM3			ENSG00000138771	NA	NA	rs13146355-A	rs13146355	0	13146355	intron_variant	0	0.21	9e-12	11.0457574905607		0.0047	[0.0033-0.0061] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	5q35.3	5	177367190	RGS14	RGS14			ENSG00000169220	NA	NA	rs12654812-A	rs12654812	0	12654812	intron_variant	0	0.36	5e-07	6.30102999566398		0.0036	[0.0022-0.0050] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	15q21.3	15	53650731	WDR72	WDR72			ENSG00000166415	NA	NA	rs17730436-T	rs17730436	0	17730436	intron_variant	0	0.60	1e-13	13		0.005	[0.0036-0.0064] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	16p12.3	16	20389517	UMOD	PDILT, AC106796.1			ENSG00000169340, ENSG00000263237	NA	NA	rs11864909-C	rs11864909	0	11864909	intron_variant	0	0.81	1e-10	10		0.0052	[0.0036-0.0068] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (sCR)	42,257 East Asian, South Asian, and South East Asian ancestry individuals	19,662 East Asian ancestry individuals	17q23.2	17	61379228	BCAS3	AC005746.2, BCAS3			ENSG00000267131, ENSG00000141376	NA	NA	rs9895661-C	rs9895661	0	9895661	non_coding_transcript_exon_variant	0	0.52	7e-11	10.1549019599857		0.0045	[0.0031-0.0059] mg/dl increase	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	6p21.33	6	31472892	MHC	HCP5			ENSG00000206337	NA	NA	rs3828890-G	rs3828890	0	3828890	intron_variant	0	0.11	1e-09	9		0.0079	[0.0054-0.0105] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	9q32	9	114228791	KIF12, ORM1, COL27A1	COL27A1			ENSG00000196739	NA	NA	rs7868992-G	rs7868992	0	7868992	intron_variant	0	0.28	3e-08	7.52287874528034		1.29	[NR]	Illumina [484295]	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	12q23.3	12	106391776	POLR3B, TCP11L2, FLJ45508	POLR3B			ENSG00000013503	NA	NA	rs6539267-T	rs6539267	0	6539267	intron_variant	0	0.69	6e-06	5.22184874961636		1.27	[NR]	Illumina [484295]	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	11q14.2	11	86072696	PICALM	PICALM - RNU6-560P	ENSG00000073921	ENSG00000200877		2814	80531	rs621942-A	rs621942	0	621942	intergenic_variant	1	.24	9e-06	5.04575749056067		1.22	[NR]	Illumina [484295]	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	6p22.3	6	23077083	intergenic	AL035401.1 - AL591416.1	ENSG00000233358	ENSG00000218476		45303	25597	rs9393366-A	rs9393366	0	9393366	intergenic_variant	1	0.28	8e-06	5.09691001300806		1.27	[NR]	Illumina [484295]	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	Xp22.11	X	22116540	PHEX	PHEX			ENSG00000102174	NA	NA	rs5951698-G	rs5951698	0	5951698	intron_variant	0	0.0032	6e-06	5.22184874961636		5.65	[NR]	Illumina [484295]	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	9q31.1	9	102740216	intergenic	LINC00587 - AL365396.1	ENSG00000204250	ENSG00000234269		82702	182358	rs10990268-C	rs10990268	0	10990268	intergenic_variant	1	0.12	5e-06	5.30102999566398		1.29	[NR]	Illumina [484295]	N
2012-10-23	22889924	Scharf JM	2012-08-14	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22889924	Genome-wide association study of Tourette's syndrome.	Tourette syndrome	778 European ancestry cases, 4,414 European ancestry controls, 242 Ashkenazi Jewish cases, 354 Ashkenazi Jewish controls, 265 French Canadian founder cases, 196 French Canadian founder controls	211 Latin American cases, 285 Latin American controls	7p21.3	7	12020180	THSD7A, TMEM106B	THSD7A - TMEM106B	ENSG00000005108	ENSG00000106460		187982	191090	rs769111-T	rs769111	0	769111	intergenic_variant	1	0.62	6e-06	5.22184874961636		1.23	[NR]	Illumina [484295]	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	7p22.3	7	1245559	UNCX	UNCX - AC073094.1	ENSG00000164853	ENSG00000233082		8233	21794	rs10277115-T	rs10277115	0	10277115	regulatory_region_variant	1	0.35	1e-10	10		0.0058	[0.0040-0.0076] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	11p14.1	11	30727543	DCDC5, MPPED2	MPPED2-AS1 - AL122014.1	ENSG00000254489	ENSG00000287373		94960	46370	rs963837-T	rs963837	0	963837	intergenic_variant	1	0.64	1e-09	9		0.0043	[0.0029-0.0057] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	4q21.1	4	76490987	SHROOM3	SHROOM3			ENSG00000138771	NA	NA	rs13146355-A	rs13146355	0	13146355	intron_variant	0	0.21	7e-11	10.1549019599857		0.0051	[0.0035-0.0067] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	5q35.3	5	177367190	RGS14	RGS14			ENSG00000169220	NA	NA	rs12654812-A	rs12654812	0	12654812	intron_variant	0	0.36	2e-07	6.69897000433602		0.0042	[0.0026-0.0058] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	6q16.3	6	101226414	GRIK2	GRIK2			ENSG00000164418	NA	NA	rs2797369-T	rs2797369	0	2797369	intron_variant	0	0.66	1e-07	7		0.0042	[0.0026-0.0058] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	15q21.3	15	53650731	WDR72	WDR72			ENSG00000166415	NA	NA	rs17730436-T	rs17730436	0	17730436	intron_variant	0	0.60	6e-13	12.2218487496164		0.0055	[0.0039-0.0071] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	16p12.3	16	20389517	UMOD	PDILT, AC106796.1			ENSG00000169340, ENSG00000263237	NA	NA	rs11864909-C	rs11864909	0	11864909	intron_variant	0	0.81	4e-10	9.39794000867204		0.0057	[0.0039-0.0075] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	17q23.2	17	61379228	BCAS3	AC005746.2, BCAS3			ENSG00000267131, ENSG00000141376	NA	NA	rs9895661-C	rs9895661	0	9895661	non_coding_transcript_exon_variant	0	0.52	5e-11	10.301029995664		0.0051	[0.0035-0.0067] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (eGRFcrea)	42,451 East Asian, South Asian, and South East Asian ancestry individuals	19,636 East Asian ancestry individuals	6q25.2	6	154665530	CNKSR3, RBM16	AL591419.1 - AL591499.1	ENSG00000231316	ENSG00000205625		59576	41113	rs9397738-G	rs9397738	0	9397738	intergenic_variant	1	0.22	5e-06	5.30102999566398		0.0039	[0.0021-0.0057] ml/min/1.73m2 decrease	Affymetrix, Illumina [2353587] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (urea)	21,417 East Asian ancestry individuals	11,657 East Asian ancestry individuals	16q23.2	16	79612092	MAF	AC009159.3 - AC009159.1	ENSG00000278058	ENSG00000275040		5487	7377	rs889472-C	rs889472	0	889472	intergenic_variant	1	0.57	1e-09	9		0.0711	[0.048-0.094] mg/dl increase	Affymetrix, Illumina [2278301] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (urea)	21,417 East Asian ancestry individuals	11,657 East Asian ancestry individuals	4p16.1	4	9993558	SLC2A9	SLC2A9			ENSG00000109667	NA	NA	rs3775948-C	rs3775948	0	3775948	intron_variant	0	0.59	2e-65	64.698970004336		0.1786	[0.16-0.20] mg/dl increase	Affymetrix, Illumina [2278301] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (urea)	21,417 East Asian ancestry individuals	11,657 East Asian ancestry individuals	4q22.1	4	88038770	ABCG2	PKD2			ENSG00000118762	NA	NA	rs2725220-C	rs2725220	0	2725220	intron_variant	0	0.32	4e-30	29.397940008672		0.135	[0.11-0.16] mg/dl increase	Affymetrix, Illumina [2278301] (imputed)	N
2012-09-18	22797727	Okada Y	2012-07-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22797727	Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.	Renal function-related traits (urea)	21,417 East Asian ancestry individuals	11,657 East Asian ancestry individuals	11q13.1	11	64696613	SLC22A12	NRXN2			ENSG00000110076	NA	NA	rs504915-T	rs504915	0	504915	intron_variant	0	0.82	3e-63	62.5228787452803		0.2251	[0.20-0.25] mg/dl increase	Affymetrix, Illumina [2278301] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	1q32.2	1	210995417	KCNH1	KCNH1, AL590132.1			ENSG00000143473, ENSG00000284299	NA	NA	rs1501550-A	rs1501550	0	1501550	intron_variant	0	0.21	2e-06	5.69897000433602	(ADM)	0.011	[0.0071-0.0149] nmol/l decrease	Illumina [2269099] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	4q35.2	4	186227233	KLKB1	KLKB1			ENSG00000164344	NA	NA	rs4253238-C	rs4253238	0	4253238	intron_variant	0	0.46	4e-52	51.397940008672	(ADM)	0.031	[0.027-0.035] nmol/l increase	Illumina [2269099] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	4q35.2	4	186227233	KLKB1	KLKB1			ENSG00000164344	NA	NA	rs4253238-C	rs4253238	0	4253238	intron_variant	0	0.46	1e-122	122	(ET)	5.136	[4.71-5.56] pmol/l increase	Illumina [2269099] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	5q35.3	5	177415473	F12	GRK6			ENSG00000198055	NA	NA	rs2731672-T	rs2731672	0	2731672	intron_variant	0	0.24	6e-24	23.2218487496164	(ADM)	0.022	[0.018-0.026] nmol/l increase	Illumina [2269099] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	5q35.3	5	177415473	F12	GRK6			ENSG00000198055	NA	NA	rs2731672-T	rs2731672	0	2731672	intron_variant	0	0.24	1e-67	67	(ET)	4.61	[4.09-5.13] pmol/l increase	Illumina [2269099] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	6p24.1	6	12296022	EDN1	EDN1			ENSG00000078401	NA	NA	rs5370-T	rs5370	0	5370	missense_variant	0	0.22	1e-27	27	(ET)	2.955	[2.42-3.49] pmol/l increase	Illumina [2269099] (imputed)	N
2013-05-09	23381795	Verweij N	2013-02-04	Hypertension	www.ncbi.nlm.nih.gov/pubmed/23381795	Genome-wide association study on plasma levels of midregional-proadrenomedullin and C-terminal-pro-endothelin-1.	Circulating vasoactive peptide levels	3,444 European ancestry individuals	3,230 European ancestry individuals	11p15.4	11	10346572	ADM	AMPD3			ENSG00000133805	NA	NA	rs2957692-G	rs2957692	0	2957692	intron_variant	0	0.40	1e-12	12	(ADM)	0.015	[0.011-0.019] nmol/l decrease	Illumina [2269099] (imputed)	N
2013-02-08	23223146	Le Clerc S	2012-12-06	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/23223146	A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.	Aging (facial)	502 European ancestry females	NA	3q13.33	3	120866468	FBXO40, STXBP5L	AC072026.2, AC072026.3			ENSG00000286827, ENSG00000287366	NA	NA	rs322458-G	rs322458	0	322458	intron_variant	0	NR	2e-08	7.69897000433602		NA		Illumina [795063]	N
2013-02-08	23223146	Le Clerc S	2012-12-06	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/23223146	A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.	Aging (facial)	502 European ancestry females	NA	3q13.33	3;3	120866468;121381436	FBXO40, STXBP5L	AC072026.2; AC072026.3; STXBP5L				NA	NA	rs322458-G; rs17740066-G	rs322458; rs17740066	0	NA	intron_variant; missense_variant	NA	NR	6e-09	8.22184874961636		NA		Illumina [795063]	N
2013-02-08	23223146	Le Clerc S	2012-12-06	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/23223146	A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.	Aging (facial)	502 European ancestry females	NA	3q13.33	3;3	120866468;121419129	FBXO40, STXBP5L	AC072026.2; AC072026.3; AC079841.2; STXBP5L				NA	NA	rs322458-G; rs6782025-A	rs322458; rs6782025	0	NA	intron_variant; 3_prime_UTR_variant	NA	NR	4e-09	8.39794000867204		NA		Illumina [795063]	N
2013-02-08	23223146	Le Clerc S	2012-12-06	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/23223146	A genome-wide association study in Caucasian women points out a putative role of the STXBP5L gene in facial photoaging.	Aging (facial)	502 European ancestry females	NA	3q13.33	3;3	120866468;121600977	POLQ, FBXO40, STXBP5L	AC072026.2; AC072026.3; FBXO40				NA	NA	rs322458-G; rs6775899-A	rs322458; rs6775899	0	NA	intron_variant; intron_variant	NA	NR	1e-09	9		NA		Illumina [795063]	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5p15.1	5	16812529	MYO10	MYO10			ENSG00000145555	NA	NA	rs17651119-C	rs17651119	0	17651119	intron_variant	0	0.99	2e-08	7.69897000433602	(% improvement - 12 weeks)	3.1807	[2.77-3.59]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	7q11.22	7	71008019	WBSCR17	AC073873.1 - GALNT17	ENSG00000236978	ENSG00000185274		170006	124125	rs1525293-C	rs1525293	0	1525293	intergenic_variant	1	0.66	2e-06	5.69897000433602	(remission - SSRI treated - 12 weeks)	1.7041	[1.48-1.92]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	1q42.13	1	227480089	intergenic	BTF3P9 - AL451054.2	ENSG00000224834	ENSG00000237193		45743	2164	rs12410462-A	rs12410462	0	12410462	intergenic_variant	1	0.122	4e-07	6.39794000867204	(% improvement - 12 weeks)	1.259	[1.16-1.36]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	14q23.2	14	62855629	KCNH5	KCNH5			ENSG00000140015	NA	NA	rs8012941-G	rs8012941	0	8012941	intron_variant	0	0.4975174	4e-06	5.39794000867204	(remission - SSRI treated - 12 weeks)	1.5387	[1.35-1.72]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	18p11.21	18	10923810	FAM38B	PIEZO2			ENSG00000154864	NA	NA	rs264272-G	rs264272	0	264272	intron_variant	0	0.52	4e-06	5.39794000867204	(% improvement - 12 weeks)	1.144	[1.09-1.2]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	13q31.1	13	79594869	NDFIP2	LINC01068 - AL136442.1	ENSG00000227676	ENSG00000285902		23424	42564	rs9601248-C	rs9601248	0	9601248	intergenic_variant	1	0.498	2e-06	5.69897000433602	(remission - 12 weeks)	1.3841	[1.25-1.52]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	4q28.1	4	124344158	intergenic	AC133530.1 - AC097474.1	ENSG00000286734	ENSG00000248506		5111	91592	rs2125000-T	rs2125000	0	2125000	intergenic_variant	1	0.307	3e-06	5.52287874528034	(remission - 12 weeks)	1.425	[1.27-1.58]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q32	5	149657413	FLJ41603	ARHGEF37 - AC022100.1	ENSG00000183111	ENSG00000287323		22445	36824	rs17710780-T	rs17710780	0	17710780	regulatory_region_variant	1	0.86	4e-06	5.39794000867204	(remission - 12 weeks)	1.662	[1.45-1.88]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	6p22.3	6	23840904	intergenic	AL133270.1 - AL139093.1	ENSG00000219453	ENSG00000278128		191130	13235	rs9466930-C	rs9466930	0	9466930	intergenic_variant	1	0.215	4e-06	5.39794000867204	(remission - 12 weeks)	1.501	[1.32-1.68]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	12p13.1	12	13488772	GRIN2B	GRIN2B			ENSG00000273079	NA	NA	rs1457614-C	rs1457614	0	1457614	intron_variant	0	0.181	8e-06	5.09691001300806	(remission - 12 weeks)	1.4652	[1.29-1.64]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	15q23	15	68304789	ITGA11	ITGA11			ENSG00000137809	NA	NA	rs7174755-T	rs7174755	0	7174755	intron_variant	0	0.63	9e-07	6.04575749056067	(% improvement - 2 weeks)	1.168	[1.11-1.23]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q33.3	5	159580770	MIR548D2	AC008691.1			ENSG00000249738	NA	NA	rs10065906-C	rs10065906	0	10065906	intron_variant	0	0.332	2e-06	5.69897000433602	(% improvement - 2 weeks)	1.1655	[1.11-1.22]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q23.2	5	124496959	intergenic	AC025465.1			ENSG00000248296	NA	NA	rs12513663-T	rs12513663	0	12513663	intron_variant	0	0.268	2e-06	5.69897000433602	(% improvement - 2 weeks)	1.184	[1.11-1.26]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	3q28	3	192100853	FGF12	AC026320.3			ENSG00000287178	NA	NA	rs4585146-G	rs4585146	0	4585146	intron_variant	0	0.65	6e-06	5.22184874961636	(% improvement - 2 weeks)	1.1643	[1.11-1.22]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q33.3	5	159580770	MIR548D2	AC008691.1			ENSG00000249738	NA	NA	rs10065906-C	rs10065906	0	10065906	intron_variant	0	0.3622876	2e-06	5.69897000433602	(partial response - SSRI treated - 2 weeks)	1.5298	[1.36-1.7]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	4q21.22	4	81541443	RASGEF1B	RASGEF1B			ENSG00000138670	NA	NA	rs1822818-T	rs1822818	0	1822818	intron_variant	0	0.87	6e-06	5.22184874961636	(partial response - SSRI treated - 2 weeks)	1.7737	[1.53-2.02]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	6p24.3	6	10175803	intergenic	OFCC1			ENSG00000181355	NA	NA	rs12210761-A	rs12210761	0	12210761	intron_variant	0	0.0676606	6e-06	5.22184874961636	(partial response - SSRI treated - 2 weeks)	2.4458	[2.06-2.83]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	7p12.3	7	45942861	IGFBP1, IGFBP3	AC073115.2			ENSG00000237471	NA	NA	rs2462686-C	rs2462686	0	2462686	intron_variant	0	0.3509068	9e-06	5.04575749056067	(partial response - SSRI treated - 2 weeks)	1.4872	[1.31-1.66]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	9q34.13	9	132757106	C9orf98	AK8			ENSG00000165695	NA	NA	rs12552369-A	rs12552369	0	12552369	intron_variant	0	0.494	8e-06	5.09691001300806	(% improvement - 2 weeks)	1.155	[1.1-1.21]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	2q32.3	2	192877447	intergenic	PCGEM1 - AC096647.1	ENSG00000227418	ENSG00000286358		100548	293257	rs10174573-T	rs10174573	0	10174573	intergenic_variant	1	0.57	2e-06	5.69897000433602	(partial response - 2 weeks)	1.564	[1.39-1.74]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	12p12.3	12	17509301	intergenic	AC048352.1			ENSG00000256389	NA	NA	rs1706631-T	rs1706631	0	1706631	intron_variant	0	0.408	6e-06	5.22184874961636	(partial response - 2 weeks)	1.3548	[1.22-1.49]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	4p15.2	4	24739335	SOD3	LINC02473 - AC006390.1	ENSG00000261121	ENSG00000251638		67767	28714	rs12500612-G	rs12500612	0	12500612	intergenic_variant	1	0.85	7e-06	5.15490195998574	(partial response - 2 weeks)	1.7665	[1.51-2.02]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	22q12.3	22	34427837	ENOX1	LINC01643 - AL021877.1	ENSG00000236052	ENSG00000235485		209041	161248	rs1034394-G	rs1034394	0	1034394	regulatory_region_variant	1	0.3390146	2e-06	5.69897000433602	(% improvement - SSRI treated - 12 weeks)	0.2107	[0.12-0.3] unit increase	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	18p11.21	18	10923810	FAM38B	PIEZO2			ENSG00000154864	NA	NA	rs264272-T	rs264272	0	264272	intron_variant	0	0.4874733	3e-06	5.52287874528034	(% improvement - SSRI treated - 12 weeks)	0.1712	[0.099-0.243] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	19q13.11	19	33830353	KCTD15, CHST8	KCTD15 - AC008556.1	ENSG00000153885	ENSG00000277013		14590	75999	rs398426-T	rs398426	0	398426	intergenic_variant	1	0.2588456	5e-06	5.30102999566398	(% improvement - SSRI treated - 12 weeks)	0.2513	[0.14-0.36] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	19q13.42	19	55754298	EPN1, NLRP9, NLRP11, RFPL4A	NLRP9 - RFPL4A	ENSG00000185792	ENSG00000223638		15896	4716	rs17634917-G	rs17634917	0	17634917	intergenic_variant	1	0.0573945	6e-06	5.22184874961636	(% improvement - SSRI treated - 12 weeks)	0.3761	[0.21-0.54] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	4q28.1	4	124494379	intergenic	TECRP2 - LINC02516	ENSG00000248565	ENSG00000261083		30589	5561	rs6534441-C	rs6534441	0	6534441	intergenic_variant	1	0.3328325	7e-06	5.15490195998574	(% improvement - SSRI treated - 12 weeks)	0.1801	[0.1-0.26] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	12p13.32	12	4307138	C12orf5, CCND2	AC008012.1			ENSG00000285901	NA	NA	rs4625554-G	rs4625554	0	4625554	intron_variant	0	0.2996789	9e-06	5.04575749056067	(% improvement - SSRI treated - 12 weeks)	0.1927	[0.11-0.28] unit increase	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	19q13.11	19	33829949	KCTD15	KCTD15 - AC008556.1	ENSG00000153885	ENSG00000277013		14186	76403	rs2546057-A	rs2546057	0	2546057	intergenic_variant	1	0.52	3e-07	6.52287874528034	(% improvement - 12 weeks)	1.183	[1.12-1.24]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	9p24.3	9	955794	DMRT3, DMRT1	DMRT1			ENSG00000137090	NA	NA	rs364477-C	rs364477	0	364477	intron_variant	0	0.2154931	4e-06	5.39794000867204	(remission - SSRI treated - 12 weeks)	1.6925	[1.47-1.92]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	19q13.42	19	55754298	RFPL4A	NLRP9 - RFPL4A	ENSG00000185792	ENSG00000223638		15896	4716	rs17634917-A	rs17634917	0	17634917	intergenic_variant	1	0.94	3e-06	5.52287874528034	(% improvement - 12 weeks)	1.371	[1.23-1.51]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	1q41	1	217027541	ESRRG	ESRRG			ENSG00000196482	NA	NA	rs2377360-G	rs2377360	0	2377360	intron_variant	0	0.2632403	9e-06	5.04575749056067	(remission - SSRI treated - 12 weeks)	1.6	[1.39-1.81]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5p14.1	5	27611324	intergenic	PURPL - AC093300.1	ENSG00000250337	ENSG00000250079		114330	602035	rs12054895-T	rs12054895	0	12054895	intergenic_variant	1	0.275456	3e-08	7.52287874528034	(% improvement - SSRI treated - 2 weeks)	0.2428	[0.16-0.33] unit increase	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	15q23	15	68304789	PIAS1, CALML4, CLN6, FEM1B, ITGA11	ITGA11			ENSG00000137809	NA	NA	rs7174755-C	rs7174755	0	7174755	intron_variant	0	0.3690476	3e-07	6.52287874528034	(% improvement - SSRI treated - 2 weeks)	0.2048	[0.13-0.28] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	19q13.11	19	32598525	PDCD5, ANKRD27, RGS9BP, NUDT19	ANKRD27			ENSG00000105186	NA	NA	rs17692896-A	rs17692896	0	17692896	intron_variant	0	0.0739179	7e-07	6.15490195998574	(% improvement - SSRI treated - 2 weeks)	0.4395	[0.27-0.61] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	6p22.3	6	16255812	MYLIP, GMPR, ATXN1	GMPR			ENSG00000137198	NA	NA	rs10484358-T	rs10484358	0	10484358	intron_variant	0	0.0827112	1e-06	6	(% improvement - SSRI treated - 2 weeks)	0.4258	[0.25-0.6] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q14.3	5	87738535	RASA1, CCNH	LINC02144 - AC020930.1	ENSG00000248708	ENSG00000287783		5266	29073	rs1673101-A	rs1673101	0	1673101	intergenic_variant	1	0.3312154	4e-06	5.39794000867204	(% improvement - SSRI treated - 2 weeks)	0.1877	[0.11-0.27] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	1p36.32	1	5294784	intergenic	LINC02782 - AL139823.1	ENSG00000231510	ENSG00000284616		203885	7144	rs912988-T	rs912988	0	912988	intergenic_variant	1	0.3630374	6e-06	5.22184874961636	(% improvement - SSRI treated - 2 weeks)	0.1825	[0.1-0.26] unit increase	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	3q29	3	193865921	intergenic	LINC02038 - LINC02026	ENSG00000229155	ENSG00000214146		21897	91451	rs604222-A	rs604222	0	604222	intergenic_variant	1	0.1915251	7e-06	5.15490195998574	(% improvement - SSRI treated - 2 weeks)	0.2173	[0.12-0.31] unit increase	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	3q25.33	3	159926508	IL12A, SCHIP1	IL12A-AS1			ENSG00000244040	NA	NA	rs6799788-G	rs6799788	0	6799788	intron_variant	0	0.2476976	1e-06	6	(partial response - SSRI treated - 2 weeks)	1.6268	[1.43-1.82]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	15q13.3	15	33212866	FMN1	FMN1 - TMCO5B	ENSG00000248905	ENSG00000215296		18133	22686	rs974379-C	rs974379	0	974379	intergenic_variant	1	0.075	8e-06	5.09691001300806	(% improvement - 2 weeks)	1.2872	[1.17-1.4]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	6p21.1	6	44097574	MRPL14	AL109615.4 - MRPL14	ENSG00000287562	ENSG00000180992		1989	15877	rs7742824-A	rs7742824	0	7742824	regulatory_region_variant	1	0.224	9e-06	5.04575749056067	(% improvement - 2 weeks)	1.185	[1.11-1.26]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q33.3	5	159580770	intergenic	AC008691.1			ENSG00000249738	NA	NA	rs10065906-C	rs10065906	0	10065906	intron_variant	0	0.308	5e-08	7.30102999566398	(partial response - 2 weeks)	1.4712	[1.33-1.61]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	5q31.3	5	141831188	PCDH1	AC005753.1 - PCDH1	ENSG00000278925	ENSG00000156453		4863	21923	rs166040-G	rs166040	0	166040	intergenic_variant	1	0.87	5e-06	5.30102999566398	(partial response - 2 weeks)	1.6054	[1.41-1.8]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	13q14.11	13	43260134	ENOX1	ENOX1			ENSG00000120658	NA	NA	rs17538444-T	rs17538444	0	17538444	intron_variant	0	0.0698752	4e-07	6.39794000867204	(% improvement - SSRI treated - 12 weeks)	0.3905	[0.24-0.54] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	15q26.3	15	99759034	LYSMD4, C15orf51	LYSMD4 - DNM1P46	ENSG00000183060	ENSG00000182397		25473	31122	rs6598266-A	rs6598266	0	6598266	intergenic_variant	1	0.1427493	3e-06	5.52287874528034	(% improvement - SSRI treated - 12 weeks)	0.2543	[0.15-0.36] unit increase	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	13q31.1	13	80783536	intergenic	AL590807.1			ENSG00000286746	NA	NA	rs11149178-A	rs11149178	0	11149178	intron_variant	0	0.3560899	7e-06	5.15490195998574	(% improvement - SSRI treated - 12 weeks)	0.1777	[0.1-0.26] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	12p13.1	12	13367062	C12orf36	AC022276.1 - LINC01559	ENSG00000286869	ENSG00000180861		88686	4027	rs11055387-C	rs11055387	0	11055387	intergenic_variant	1	0.0895145	8e-06	5.09691001300806	(remission - SSRI treated - 12 weeks)	2.1853	[1.84-2.53]	Affymetrix, Illumina [1200000] (imputed)	N
2013-05-09	23377640	GENDEP Investigators	2013-02-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23377640	Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.	Major depressive disorder	Up to 2,256 European ancestry cases	NA	3q28	3	192100853	FGF12	AC026320.3			ENSG00000287178	NA	NA	rs4585146-A	rs4585146	0	4585146	intron_variant	0	0.362271	3e-07	6.52287874528034	(% improvement - SSRI treated - 2 weeks)	0.2208	[0.14-0.31] unit decrease	Affymetrix, Illumina [1200000] (imputed)	N
2013-03-22	23269536	Sun J	2012-12-27	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23269536	Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population.	Prostate-specific antigen levels	1,999 Chinese ancestry males	1,496 Chinese ancestry males	1q32.1	1	205669094	SLC45A3, NUCKS1, RAB7L1, SLC41A1, FLJ32569	SLC45A3			ENSG00000158715	NA	NA	rs12409639-A	rs12409639	0	12409639	intron_variant	0	0.11	2e-19	18.698970004336		0.2	[NR] % increase	Illumina [> 709211] (imputed)	N
2013-03-22	23269536	Sun J	2012-12-27	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23269536	Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population.	Prostate-specific antigen levels	1,999 Chinese ancestry males	1,496 Chinese ancestry males	10q11.22	10	46046326	MSMB	MSMB			ENSG00000263639	NA	NA	rs10993994-T	rs10993994	0	10993994	5_prime_UTR_variant	0	0.50	5e-17	16.301029995664		0.12	[NR] % increase	Illumina [> 709211] (imputed)	N
2013-03-22	23269536	Sun J	2012-12-27	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23269536	Genome-wide association study identified novel genetic variant on SLC45A3 gene associated with serum levels prostate-specific antigen (PSA) in a Chinese population.	Prostate-specific antigen levels	1,999 Chinese ancestry males	1,496 Chinese ancestry males	19q13.33	19	50861367	KLK3	KLK3 - KLK2	ENSG00000142515	ENSG00000167751		603	201	rs2735839-G	rs2735839	0	2735839	intergenic_variant	1	0.58	6e-37	36.2218487496164		0.19	[NR] % increase	Illumina [> 709211] (imputed)	N
2012-09-11	22764253	Thier S	2012-07-03	Neurology	www.ncbi.nlm.nih.gov/pubmed/22764253	Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor.	Essential tremor	436 European ancestry cases, 928 European ancestry controls	554 European ancestry cases, 609 European ancestry controls	11p13	11	35308068	SLC1A2	SLC1A2			ENSG00000110436	NA	NA	rs3794087-?	rs3794087	0	3794087	intron_variant	0	NR	1e-07	7		1.43	[1.26-1.64]	Affymetrix [620077]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	2q37.2	2	235886699	CENTG2	AGAP1			ENSG00000157985	NA	NA	rs13025591-?	rs13025591	0	13025591	intron_variant	0	NR	8e-08	7.09691001300806		1.11	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	12p13.33	12	2240418	TCF4	CACNA1C, CACNA1C			ENSG00000151067, ENSG00000285479	NA	NA	rs17597926-?	rs4765905	0	4765905	intron_variant	0	NR	1e-07	7		1.36	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	12p13.33	12	2240418	CACNA1C	CACNA1C, CACNA1C			ENSG00000151067, ENSG00000285479	NA	NA	rs4765905-?	rs4765905	0	4765905	intron_variant	0	NR	2e-07	6.69897000433602		1.11	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	10q24.33	10	103146454	NT5C2, other genes, CNNM2	NT5C2			ENSG00000076685	NA	NA	rs11191580-?	rs11191580	0	11191580	intron_variant	0	NR	2e-09	8.69897000433602		1.23	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	15q22.2	15	61578744	intergenic	AC104574.2			ENSG00000259616	NA	NA	rs12592967-?	rs12592967	0	12592967	intron_variant	0	NR	3e-07	6.52287874528034		1.1	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	11q25	11	130960853	intergenic	SNX19 - RN7SL167P	ENSG00000120451	ENSG00000242673		44344	43275	rs10894294-?	rs10894294	0	10894294	intergenic_variant	1	NR	3e-07	6.52287874528034		1.1	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	1p21.3	1	98087276	DPYD, has-mir-137	NFU1P2 - LINC01776	ENSG00000233557	ENSG00000226053		9808	123471	rs1198588-?	rs1198588	0	1198588	intergenic_variant	1	NR	5e-07	6.30102999566398		1.12	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	1p21.3	1	96648359	PTBP2	NDUFS5P2 - RPL7P9	ENSG00000234226	ENSG00000137970		63632	30515	rs12071951-?	rs12071951	0	12071951	intergenic_variant	1	NR	5e-07	6.30102999566398		1.14	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	7p22.3	7	1964786	SNX8, NUDT1, FTSJ2, MAD1L1	MAD1L1, AC069288.1			ENSG00000002822, ENSG00000286192	NA	NA	rs12666575-?	rs12666575	0	12666575	intron_variant	0	NR	2e-09	8.69897000433602		1.12	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	5q12.1	5	61435631	intergenic	ZSWIM6			ENSG00000130449	NA	NA	rs7709645-?	rs7709645	0	7709645	intron_variant	0	NR	4e-08	7.39794000867204		1.11	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	8q21.3	8	88748082	MMP16	AC090578.1			ENSG00000253553	NA	NA	rs7004633-?	rs7004633	0	7004633	intron_variant	0	NR	6e-08	7.22184874961636		1.15	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	11q24.2	11	125454069	FEZ1, El24, PKNOX2	FEZ1			ENSG00000149557	NA	NA	rs11220082-?	rs11220082	0	11220082	intron_variant	0	NR	7e-07	6.15490195998574		1.1	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	10q21.2	10	60586880	intergenic	ANK3			ENSG00000151150	NA	NA	rs16915157-?	rs16915157	0	16915157	intron_variant	0	NR	7e-07	6.15490195998574		1.13	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	8p23.2	8	4356657	CSMD1	CSMD1			ENSG00000183117	NA	NA	rs10503256-?	rs10503256	0	10503256	intron_variant	0	NR	9e-07	6.04575749056067		1.1	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Schizophrenia	2,111 European ancestry cases, 2,535 European ancestry controls	11,271 European ancestry cases, 14,601 European ancestry controls	6p22.1	6	27742386	MHC	GPR89P - AL009179.2	ENSG00000216915	ENSG00000287252		3892	17484	rs17693963-?	rs17693963	0	17693963	intergenic_variant	1	NR	3e-11	10.5228787452803		1.24	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	6p21.32	6	32390493	other genes, MHC	TSBP1-AS1			ENSG00000225914	NA	NA	rs3117099-?	rs3117099	0	3117099	non_coding_transcript_exon_variant	0	NR	3e-06	5.52287874528034		1.25	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	4q34.3	4	179734472	intergenic	AC020551.1 - AC021193.1	ENSG00000250993	ENSG00000248921		269167	122381	rs17746001-T	rs17746001	0	17746001	intergenic_variant	1	NR	3e-07	6.52287874528034		1.75	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	4q34.3	4	179734472	intergenic	AC020551.1 - AC021193.1	ENSG00000250993	ENSG00000248921		269167	122381	rs17746001-?	rs17746001	0	17746001	intergenic_variant	1	NR	3e-07	6.52287874528034		1.75	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	6p21.33	6	30814225	other genes, MHC	LINC00243			ENSG00000214894	NA	NA	rs886424-?	rs886424	0	886424	non_coding_transcript_exon_variant	0	NR	9e-07	6.04575749056067		1.37	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	3q26.32	3	178623794	KCNMB2	AC117457.1, KCNMB2-AS1, KCNMB2			ENSG00000275163, ENSG00000237978, ENSG00000197584	NA	NA	rs2054399-?	rs2054399	0	2054399	intron_variant	0	NR	1e-06	6		1.22	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	16q13	16	57024670	NLRC5	NLRC5			ENSG00000140853	NA	NA	rs821470-A	rs821470	0	821470	intron_variant	0	NR	3e-06	5.52287874528034		1.25	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	8p23.1	8	10129145	MSRA	AC023385.1, MSRA, MSRA			ENSG00000285675, ENSG00000175806, ENSG00000285250	NA	NA	rs1484642-C	rs1484642	0	1484642	intron_variant	0	NR	3e-06	5.52287874528034		1.43	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	10q26.11	10	117422360	intergenic	PDZD8 - AC005871.2	ENSG00000165650	ENSG00000258114		46920	2834	rs181500-T	rs181500	0	181500	regulatory_region_variant	1	NR	5e-06	5.30102999566398		1.24	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	5q33.1	5	152908893	NMUR2	LINC01470			ENSG00000249484	NA	NA	rs4262150-?	rs4262150	0	4262150	intron_variant	0	NR	7e-06	5.15490195998574		1.22	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	5q23.1	5	116233060	COMMD10	COMMD10			ENSG00000145781	NA	NA	rs253959-T	rs253959	0	253959	intron_variant	0	NR	8e-06	5.09691001300806		1.21	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	2q33.3	2	206257058	ZDBF2, GPR1, ADAM23	GPR1-AS, GPR1-AS			ENSG00000279220, ENSG00000283643	NA	NA	rs2058710-A	rs2058710	0	2058710	intron_variant	0	NR	9e-06	5.04575749056067		1.24	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	6p22.1	6	29931900	other genes, MHC	HLA-K - HLA-U	ENSG00000232708	ENSG00000228078		2668	2201	rs2524005-?	rs2524005	0	2524005	intron_variant	1	NR	5e-07	6.30102999566398		1.32	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder and schizophrenia	2,111 European ancestry schizophrenia cases, 836 European ancestry bipolar disorder cases, 2,535 European ancestry controls	NA	9q22.31	9	92060258	SPTLC1, ROR2	SPTLC1			ENSG00000090054	NA	NA	rs7872515-?	rs7872515	0	7872515	intron_variant	0	NR	6e-07	6.22184874961636		1.39	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder	836 European ancestry cases, 2,093 European ancestry controls	NA	4q34.3	4	179734472	intergenic	AC020551.1 - AC021193.1	ENSG00000250993	ENSG00000248921		269167	122381	rs17746001-T	rs17746001	0	17746001	intergenic_variant	1	NR	3e-07	6.52287874528034		2.03	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder	836 European ancestry cases, 2,093 European ancestry controls	NA	12q23.3	12	108349043	CMKLR1	CMKLR1 - LINC01498	ENSG00000174600	ENSG00000247213		9726	85087	rs17040430-T	rs17040430	0	17040430	regulatory_region_variant	1	NR	9e-07	6.04575749056067		1.89	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder	836 European ancestry cases, 2,093 European ancestry controls	NA	1q42.2	1	234527144	IRF2BP2	TARBP1 - LINC01354	ENSG00000059588	ENSG00000231768		47965	743	rs271738-A	rs271738	0	271738	intergenic_variant	1	NR	5e-06	5.30102999566398		1.32	[NR]	Affymetrix [745006]	N
2012-08-14	22688191	Bergen SE	2012-06-12	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22688191	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	Bipolar disorder	836 European ancestry cases, 2,093 European ancestry controls	NA	8p22	8	13403027	DLC1	DLC1			ENSG00000164741	NA	NA	rs289585-?	rs289585	0	289585	non_coding_transcript_exon_variant	0	NR	5e-06	5.30102999566398		1.45	[NR]	Affymetrix [745006]	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	1p36.11	1	24946709	RUNX3	RUNX3			ENSG00000020633	NA	NA	rs7551188-T	rs7551188	0	7551188	intron_variant	0	NR	9e-06	5.04575749056067		1.18	[1.10-1.28]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	4p14	4	38334202	TBC1D1	AC098680.1 - LINC02513	ENSG00000251642	ENSG00000248227		46711	32712	rs1487630-T	rs1487630	0	1487630	intergenic_variant	1	NR	1e-11	11		1.33	[1.22-1.44]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	13q14.11	13	40983974	WBP4, ELF1, microRNA2276, SLC25A15	ELF1			ENSG00000120690	NA	NA	rs7329174-G	rs7329174	0	7329174	intron_variant	0	NR	8e-09	8.09691001300806		1.27	[1.17-1.38]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	17q21.2	17	42355962	STAT3	STAT3			ENSG00000168610	NA	NA	rs9891119-A	rs9891119	0	9891119	intron_variant	0	NR	2e-15	14.698970004336		1.37	[1.27-1.48]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	2p25.2	2	5523876	SOX11	AC073143.1 - AC107057.1	ENSG00000228585	ENSG00000232835		209742	25904	rs11894081-T	rs11894081	0	11894081	intergenic_variant	1	0.55	4e-09	8.39794000867204		1.22	[1.2-1.22]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	11q13.4	11	72959855	ATG16L2, FCHSD2	FCHSD2			ENSG00000137478	NA	NA	rs72981516-T	rs72981516	0	72981516	intron_variant	0	0.12	4e-07	6.39794000867204		1.28	[1.27-1.29]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	6p21.33	6	31174468	PSORS1C3	PSORS1C3, PSORS1C3, PSORS1C3, PSORS1C3, PSORS1C3, PSORS1C3, PSORS1C3, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1, POU5F1			ENSG00000223364, ENSG00000224056, ENSG00000226422, ENSG00000230983, ENSG00000224744, ENSG00000231450, ENSG00000204528, ENSG00000204531, ENSG00000233911, ENSG00000229094, ENSG00000230336, ENSG00000206454, ENSG00000237582, ENSG00000235068	NA	NA	rs3094188-C	rs3094188	0	3094188	intron_variant	0	0.280	7e-07	6.15490195998574		1.61	[1.33-1.94]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	6p21.32	6	32237333	PBX2, NOTCH4	NOTCH4 - TSBP1-AS1	ENSG00000238196	ENSG00000225914		13266	17307	rs9267911-T	rs9267911	0	9267911	intergenic_variant	1	0.479	3e-07	6.52287874528034		1.5	[1.29-1.76]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	6p21.32	6	32713151	HLA-DQA2, HLA-DOB, HLA-DQB1, PSMB9, HLA-DRB1, HLA-DQA1	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		6196	4854	rs7765379-G	rs7765379	0	7765379	regulatory_region_variant	1	NR	9e-59	58.0457574905607		1.93	[1.78-2.09]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	9p24.1	9	4985879	JAK2	JAK2			ENSG00000096968	NA	NA	rs2274471-A	rs2274471	0	2274471	intron_variant	0	NR	5e-06	5.30102999566398		1.27	[1.15-1.41]	Illumina [4929034] (imputed)	N
2013-02-27	23266558	Yamazaki K	2012-12-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/23266558	A genome-wide association study identifies 2 susceptibility Loci for Crohn's disease in a Japanese population.	Crohn's disease	372 Japanese ancestry cases,3,389 Japanese ancestry controls	Up to 1,151 Japanese ancestry cases, up to 15,800 Japanese ancestry controls	9q32	9	114783386	LOC100129633, LOC645266, TNFSF8, TNFSF15	AL390240.1 - TNFSF15	ENSG00000274919	ENSG00000181634		8266	1266	rs6478106-T	rs6478106	0	6478106	intergenic_variant	1	NR	5e-46	45.301029995664		1.73	[1.60-1.86]	Illumina [4929034] (imputed)	N
2013-05-01	23382809	Xu C	2013-01-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23382809	BCL9 and C9orf5 are associated with negative symptoms in schizophrenia: meta-analysis of two genome-wide association studies.	Schizophrenia (negative symptoms)	1,774 European ancestry cases, 2,726 European ancestry controls		9q31.3	9	109037283	C9orf5	TMEM245			ENSG00000106771	NA	NA	rs643410-A	rs643410	0	643410	intron_variant	0	0.05	1e-06	6		1.6	[NR]	Affymetrix [729454]	N
2013-05-01	23382809	Xu C	2013-01-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23382809	BCL9 and C9orf5 are associated with negative symptoms in schizophrenia: meta-analysis of two genome-wide association studies.	Schizophrenia (negative symptoms)	1,774 European ancestry cases, 2,726 European ancestry controls		1q21.2	1	147611315	BCL9	BCL9			ENSG00000116128	NA	NA	rs583583-A	rs583583	0	583583	intron_variant	0	0.28	6e-07	6.22184874961636		1.3	[NR]	Affymetrix [729454]	N
2013-05-01	23382809	Xu C	2013-01-29	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23382809	BCL9 and C9orf5 are associated with negative symptoms in schizophrenia: meta-analysis of two genome-wide association studies.	Schizophrenia (negative symptoms)	1,774 European ancestry cases, 2,726 European ancestry controls		8q24.22	8	133656434	ST3Gal1	AC090821.1 - Metazoa_SRP	ENSG00000212273	ENSG00000278569		11709	11986	rs2860223-C	rs2860223	0	2860223	regulatory_region_variant	1	0.35	2e-06	5.69897000433602		1.26	[NR]	Affymetrix [729454]	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	8q24.12	8	118995181	TNFRSF11B	AC107953.1 - COLEC10	ENSG00000254247	ENSG00000184374		12306	271	rs2062377-A	rs2062377	0	2062377	regulatory_region_variant	1	0.57	1e-07	7	(Cortical vBMD)	0.08	[0.041-0.119] unit decrease	Illumina [2401124] (imputed)	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	13q14.11	13	42541997	TNFSF11	LINC02341 - TNFSF11	ENSG00000283554	ENSG00000120659		56041	20739	rs1021188-C	rs1021188	0	1021188	intergenic_variant	1	0.17	4e-14	13.397940008672	(Cortical vBMD)	0.15	[0.11-0.19] unit decrease	Illumina [2401124] (imputed)	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	6q23.2	6	132994665	LOC285735	LINC00326			ENSG00000231023	NA	NA	rs271170-T	rs271170	0	271170	intron_variant	0	0.33	3e-12	11.5228787452803	(Cortical vBMD)	0.11	[0.071-0.149] unit decrease	Illumina [2401124] (imputed)	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	8q24.12	8	118964303	TNFRSF11B	TNFRSF11B - RNU6-12P	ENSG00000164761	ENSG00000207334		12418	12210	rs7839059-A	rs7839059	0	7839059	intergenic_variant	1	0.34	1e-10	10	(Cortical vBMD)	0.1	[0.061-0.139] unit decrease	Illumina [2401124] (imputed)	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	6q25.1	6	151574321	ESR1, C6orf97	CCDC170			ENSG00000120262	NA	NA	rs6909279-G	rs6909279	0	6909279	intron_variant	0	0.40	1e-09	9	(Cortical vBMD)	0.09	[0.070-0.110] unit decrease	Illumina [2401124] (imputed)	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	13q14.11	13	42382485	TNFSF11	LINC02341			ENSG00000283554	NA	NA	rs17638544-T	rs17638544	0	17638544	intron_variant	0	0.07	5e-06	5.30102999566398	(Cortical vBMD - conditional on rs1021188)	0.13	[0.071-0.189] unit increase	Illumina [2401124] (imputed)	N
2013-05-21	23437003	Paternoster L	2013-02-21	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23437003	Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure.	Bone mineral density	up to 5,878 European ancestry individuals	up to 1,052 European ancestry individuals	1q43	1	240433914	FMN2	FMN2			ENSG00000155816	NA	NA	rs9287237-T	rs9287237	0	9287237	intron_variant	0	0.15	2e-09	8.69897000433602	(Trabecular vBMD)	0.19	[0.13-0.25] unit increase	Illumina [2401124] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	1q31.3	1	196727803	CFHR4	CFH			ENSG00000000971	NA	NA	rs1410996-G	rs1410996	0	1410996	intron_variant	0	0.585	1e-09	9	(FXIIIA)	0.203	[0.14-0.27] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	1p21.3	1	94586920	F3	AC093117.1			ENSG00000223675	NA	NA	rs2022309-G	rs2022309	0	2022309	intron_variant	0	0.701	4e-08	7.39794000867204	(D-dimer)	0.244	[0.16-0.33] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	1q31.3	1	197101646	CFHR4	ASPM			ENSG00000066279	NA	NA	rs10922162-C	rs10922162	0	10922162	synonymous_variant	0	0.839	2e-30	29.698970004336	(FXIIIA)	0.521	[0.43-0.61] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	1q31.3	1	197004053	CFHR4	CFHR5			ENSG00000134389	NA	NA	rs12116643-T	rs12116643	0	12116643	intron_variant	0	0.84	5e-30	29.301029995664	(FXIIIA)	0.515	[0.43-0.6] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	9q34.2	9	133278431	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		2407	59297	rs651007-C	rs651007	0	651007	intergenic_variant	1	0.81	2e-25	24.698970004336	(FVIII)	0.461	[0.37-0.55] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	13q34	13	113139535	F7/F10	F10			ENSG00000126218	NA	NA	rs3211770-G	rs3211770	0	3211770	intron_variant	0	0.879	3e-19	18.5228787452803	(FVII:C)	0.534	[0.42-0.65] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	1q31.3	1	197185891	CFHR4	ZBTB41			ENSG00000177888	NA	NA	rs7410943-A	rs7410943	0	7410943	intron_variant	0	0.531	3e-19	18.5228787452803	(FXIIIB)	0.301	[0.23-0.37] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	1q31.3	1	196917640	CFHR4	CFHR4			ENSG00000134365	NA	NA	rs4915559-T	rs4915559	0	4915559	intron_variant	0	0.759	7e-19	18.1549019599857	(FXIIIA)	0.339	[0.26-0.41] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	6p25.1	6	6337273	F13A1	F13A1 - LY86-AS1	ENSG00000124491	ENSG00000216863		16260	9192	rs11243081-C	rs11243081	0	11243081	intergenic_variant	1	0.676	5e-18	17.301029995664	(FXIIIA)	0.299	[0.23-0.37] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	6p25.1	6	6341054	F13A1	F13A1 - LY86-AS1	ENSG00000124491	ENSG00000216863		20041	5411	rs17142067-A	rs17142067	0	17142067	intergenic_variant	1	0.67	1e-17	17	(FXIIIA)	0.299	[0.23-0.37] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	9q34.2	9	133256028	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs8176743-C	rs8176743	0	8176743	missense_variant	0	0.939	2e-17	16.698970004336	(vWF)	0.582	[0.45-0.72] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	6p25.1	6	6331703	F13A1	F13A1 - LY86-AS1	ENSG00000124491	ENSG00000216863		10690	14762	rs1318606-T	rs1318606	0	1318606	intergenic_variant	1	0.569	4e-17	16.397940008672	(FXIIIA)	0.273	[0.21-0.34] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	13q34	13	113102226	F7/F10	MCF2L - F7	ENSG00000126217	ENSG00000057593		2484	3562	rs555212-G	rs555212	0	555212	intergenic_variant	1	0.768	1e-15	15	(FVII:C)	0.367	[0.28-0.46] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	9q32	9	114325784	ORM1	ORM1			ENSG00000229314	NA	NA	rs10982156-T	rs10982156	0	10982156	intron_variant	0	0.939	2e-10	9.69897000433602	(FX)	0.456	[0.31-0.6] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	5p15.31	5	6324180	FLJ33360	LINC02145			ENSG00000250490	NA	NA	rs12518614-A	rs12518614	0	12518614	intron_variant	0	0.954	2e-09	8.69897000433602	(vWF)	0.463	[0.31-0.61] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	13q14.11	13	43196338	ENOX1	AL138709.1 - ENOX1	ENSG00000276569	ENSG00000120658		15145	17180	rs9533425-G	rs9533425	0	9533425	regulatory_region_variant	1	0.801	2e-09	8.69897000433602	(Fibrin lag time)	0.308	[0.21-0.41] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	6p25.1	6	6318562	F13A1	F13A1			ENSG00000124491	NA	NA	rs5985-C	rs5985	0	5985	missense_variant	0	0.741	3e-186	185.52287874528	(FXIII activity)	1.077	[1-1.15] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	6p25.1	6	6317893	F13A1	F13A1			ENSG00000124491	NA	NA	rs3024321-A	rs3024321	0	3024321	intron_variant	0	0.679	8e-142	141.096910013008	(FXIII activity)	0.891	[0.82-0.96] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	9q34.2	9	133273813	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs505922-T	rs505922	0	505922	intron_variant	0	0.68	5e-57	56.301029995664	(vWF)	0.561	[0.49-0.63] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	9q34.2	9	133266942	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs643434-G	rs643434	0	643434	intron_variant	0	0.656	1e-49	49	(vWF)	0.51	[0.44-0.58] unit decrease	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	13q34	13	113098517	F7/F10	MCF2L			ENSG00000126217	NA	NA	rs10665-A	rs10665	0	10665	3_prime_UTR_variant	0	0.878	2e-47	46.698970004336	(FVII:C)	0.847	[0.73-0.96] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	13q34	13	113098850	F7/F10	MCF2L			ENSG00000126217	NA	NA	rs2181540-T	rs2181540	0	2181540	3_prime_UTR_variant	0	0.876	1e-46	46	(FVII:C)	0.834	[0.72-0.95] unit increase	Illumina [NR] (imputed)	N
2013-03-20	23381943	Williams FM	2013-01-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/23381943	Ischemic stroke is associated with the ABO locus: the EuroCLOT study.	End-stage coagulation	2,100 European ancestry individuals	NA	13q34	13	113118393	F7/F10	F7			ENSG00000057593	NA	NA	rs6041-G	rs6041	0	6041	intron_variant	0	0.892	2e-45	44.698970004336	(FVII:C)	0.877	[0.76-1] unit increase	Illumina [NR] (imputed)	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	10q25.1	10	107614626	SORCS1, LOC100128304	RNA5SP326 - LINC01435	ENSG00000200079	ENSG00000229981		152957	80347	rs11193561-A	rs11193561	0	11193561	regulatory_region_variant	1	0.239	6e-06	5.22184874961636		1.19	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	17p13.3	17	3126260	OR1D2, OR1G1	OR1E3 - OR1G1	ENSG00000142163	ENSG00000183024		8886	324	rs12449465-G	rs12449465	0	12449465	intergenic_variant	1	0.125	1e-06	6		1.26	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	2q23.3	2	150779318	RBM43, RND3	LINC02612 - AC023469.2	ENSG00000224048	ENSG00000228064		143500	203188	rs6757804-G	rs6757804	0	6757804	regulatory_region_variant	1	0.401	6e-08	7.22184874961636		1.2	[1.13-1.29]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	9p24.1	9	6253571	IL33	IL33			ENSG00000137033	NA	NA	rs10975519-A	rs10975519	0	10975519	synonymous_variant	0	0.3	9e-07	6.04575749056067		1.19	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	1p36.12	1;1;1	22096228;22113027;22123994	WNT4	CDC42; CDC42 - WNT4; WNT4				NA	NA	rs10917151-A; rs4654783-T; rs2235529-T	rs10917151; rs4654783; rs2235529	0	NA	3_prime_UTR_variant; intergenic_variant; intron_variant	NA	0.152	7e-09	8.15490195998574		1.28	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	1p36.12	1;1;1	22096228;22113027;22123994	WNT4	CDC42; CDC42 - WNT4; WNT4				NA	NA	rs10917151-G; rs4654783-G; rs2235529-C	rs10917151; rs4654783; rs2235529	0	NA	3_prime_UTR_variant; intergenic_variant; intron_variant	NA	0.709	6e-06	5.22184874961636		1.19	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	1p36.12	1;1;1;1;1	22096228;22164231;22113027;22123994;22159378	WNT4	CDC42; AL445253.1 - MIR4418; CDC42 - WNT4; WNT4; AL445253.1 - MIR4418				NA	NA	rs10917151-A; rs7521902-A; rs4654783-T; rs2235529-T; rs16826658-G	rs10917151; rs7521902; rs4654783; rs2235529; rs16826658	0	NA	3_prime_UTR_variant; intergenic_variant; intergenic_variant; intron_variant; intergenic_variant	NA	0.134	8e-07	6.09691001300806		1.25	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	1p36.12	1	22123994	LOC100289113, ZBTB40, WNT4	WNT4			ENSG00000162552	NA	NA	rs2235529-A	rs2235529	0	2235529	intron_variant	0	0.153	3e-09	8.52287874528034		1.3	[1.19-1.41]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	6p22.3	6	19803537	RNF144B, ID4	AL022068.1			ENSG00000228412	NA	NA	rs6907340-A	rs6907340	0	6907340	non_coding_transcript_exon_variant	0	0.371	2e-07	6.69897000433602		1.2	[1.12-1.28]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	7p14.3	7	31864413	PDE1C	PDE1C			ENSG00000154678	NA	NA	rs2270221-A	rs2270221	0	2270221	intron_variant	0	0.267	1e-06	6		1.2	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	8p23.2	8	5213890	LOC100287015, CSMD1	RN7SL318P - AC007718.1	ENSG00000242079	ENSG00000278256		71183	149481	rs7816936-A	rs7816936	0	7816936	intergenic_variant	1	0.446	6e-06	5.22184874961636		1.1628	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	10q11.21	10	44046117	HNRNPA3P1, LOC100130539	LINC00841 - AL137026.2	ENSG00000233395	ENSG00000237590		65015	213485	rs10508881-A	rs10508881	0	10508881	regulatory_region_variant	1	0.405	4e-07	6.39794000867204		1.19	[1.11-1.27]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	12q22	12	95302644	VEZT	VEZT			ENSG00000028203	NA	NA	rs3596-G	rs3596	0	3596	3_prime_UTR_variant	0	0.472	2e-06	5.69897000433602		1.17	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	12q24.22	12	117668389	KSR2	KSR2			ENSG00000171435	NA	NA	rs10431397-A	rs10431397	0	10431397	intron_variant	0	0.012	7e-06	5.15490195998574		1.73	[NR]	Illumina [580699]	N
2013-06-20	23472165	Albertsen HM	2013-03-05	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23472165	Genome-wide association study link novel loci to endometriosis.	Endometriosis	1,514 European ancestry cases, 12,660 European ancestry controls	505 European ancestry cases, 1,811 European ancestry controls	14q32.12	14	93178034	ITPK1, MOAP1	AL110118.1 - MOAP1	ENSG00000258595	ENSG00000165943		39569	4165	rs1268843-A	rs1268843	0	1268843	regulatory_region_variant	1	0.263	3e-06	5.52287874528034		1.19	[NR]	Illumina [580699]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	5q11.2	5	52411072	PELO	RPS17P11 - MFSD4BP1	ENSG00000244621	ENSG00000250827		128213	168483	rs6889746-?	rs6889746	0	6889746	intergenic_variant	1	.3534	6e-06	5.22184874961636	(ACL)	1.776	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	1p31.3	1	66657374	SGIP1	SGIP1			ENSG00000118473	NA	NA	rs6681460-?	rs6681460	0	6681460	intron_variant	0	0.3755	7e-06	5.15490195998574	(ACL)	1.827	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	6q14.1	6	79446542	LCA5	AL391840.1			ENSG00000231533	NA	NA	rs12204683-?	rs12204683	0	12204683	intron_variant	0	0.2378	7e-06	5.15490195998574	(ACL)	1.877	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	22q11.21	22	17965347	MICAL3	MICAL3			ENSG00000243156	NA	NA	rs1978968-?	rs1978968	0	1978968	intron_variant	0	0.2144	2e-06	5.69897000433602	(LAC)	2.235	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	2p12	2	75563363	FAM176A	EVA1A			ENSG00000115363	NA	NA	rs17011455-?	rs17011455	0	17011455	intron_variant	0	0.01661	5e-06	5.30102999566398	(LAC)	5.211	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	13q33.3	13	108728378	MYO16	MYO16			ENSG00000041515	NA	NA	rs10492418-?	rs10492418	0	10492418	intron_variant	0	0.4292	2e-06	5.69897000433602	(anti-B2 GPI)	2.172	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	7p14.3	7	32149928	PDE1C	PDE1C			ENSG00000154678	NA	NA	rs11975235-?	rs11975235	0	11975235	intron_variant	0	0.4843	3e-06	5.52287874528034	(anti-B2 GPI)	2.139	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	2q24.2	2	161029592	TANK	RN7SL423P - AC009313.2	ENSG00000244372	ENSG00000232337		151742	19014	rs2357982-?	rs2357982	0	2357982	intergenic_variant	1	0.3885	3e-06	5.52287874528034	(anti-B2 GPI)	2.189	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	20p12.1	20	16022761	MACROD2	MACROD2			ENSG00000172264	NA	NA	rs6080100-?	rs6080100	0	6080100	intron_variant	0	0.2655	7e-06	5.15490195998574	(anti-B2 GPI)	2.086	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	16q23.2	16	80158708	DYNLRB2	AC105411.1, AC022166.1			ENSG00000259867, ENSG00000260706	NA	NA	rs8060581-?	rs8060581	0	8060581	intron_variant	0	0.02466	1e-06	6	(ACL, LAC, or Anti-B2 GPI)	6.714	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	2q31.2	2	179352004	SESTD1	AC093911.1 - AC068042.1	ENSG00000237477	ENSG00000237964		66297	47724	rs13403289-?	rs13403289	0	13403289	regulatory_region_variant	1	0.3857	6e-06	5.22184874961636	(ACL, LAC, or anti-B2 GPI)	2.423	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	20p12.1	20	17585424	DSTN	DSTN			ENSG00000125868	NA	NA	rs17791782-?	rs17791782	0	17791782	intron_variant	0	0.07867	6e-06	5.22184874961636	(LAC)	2.628	[NR]	Affymetrix [906600]	N
2013-05-26	23509613	Kamboh MI	2013-02-24	Autoimmune Dis	www.ncbi.nlm.nih.gov/pubmed/23509613	Genome-wide association study of antiphospholipid antibodies.	Presence of antiphospholipid antibodies	183 European ancestry ACL-positive cases, 487 European ancestry ACL-negative controls, 127 European ancestry LAC-positive cases, 581 European ancestry LAC-negative controls, 136 European ancestry Anti-B2GPI-positive cases, 360 European ancestry Anti-B2GPI-negative controls	NA	13q14.11	13	40167770	FLJ42392	LINC00598			ENSG00000215483	NA	NA	rs9315762-?	rs9315762	0	9315762	intron_variant	0	0.1535	7e-06	5.15490195998574	(anti-B2 GPI)	2.255	[NR]	Affymetrix [906600]	N
2011-01-08	21107343	Aoki A	2010-11-25	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/21107343	SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.	Myocardial infarction	194 Japanese ancestry cases, 1,539 Japanese ancestry controls	5,177 Japanese ancestry cases, 6,220 Japanese ancestry controls	5p15.33	5	4029676	intergenic	AC025773.1 - AC025187.1	ENSG00000248962	ENSG00000249994		16027	4037	rs11748327-?	rs11748327	0	11748327	intergenic_variant	1	NR	5e-13	12.301029995664		1.25	[1.18-1.33]	Perlegen [210785]	N
2013-06-16	23474815	Stambolian D	2013-03-07	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23474815	Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error.	Refractive error	6,597 European ancestry and Erasmus Rucphen individuals, 683 Sardinian inidividuals	19,763 European ancestry individuals	16p13.3	16	7409346	RBFOX1	RBFOX1			ENSG00000078328	NA	NA	rs10500355-?	rs10500355	0	10500355	intron_variant	0	.3721	4e-09	8.39794000867204		0.111	[0.074-0.147] unit decrease	Affymetrix, Illumina [2093862] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	2p14	2	64993776	SLC1A4	SLC1A4, LINC02245			ENSG00000115902, ENSG00000237638	NA	NA	rs2160387-?	rs2160387	0	2160387	intron_variant	0	NR	3e-22	21.5228787452803	(Ala, Val)	0.17	[0.13-0.21] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	4q22.1	4	88305270	PPM1K	PPM1K-DT			ENSG00000246375	NA	NA	rs1440581-?	rs1440581	0	1440581	intron_variant	0	NR	2e-16	15.698970004336	(Fischer's ratio)	0.13	[0.091-0.169] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	5q35.3	5	177414338	F12	GRK6			ENSG00000198055	NA	NA	rs2545801-?	rs2545801	0	2545801	intron_variant	0	NR	9e-11	10.0457574905607	(Phe)	0.12	[0.081-0.159] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	10q24.2	10	97599982	DHDPSL	AL355315.1, HOGA1			ENSG00000249967, ENSG00000241935	NA	NA	rs2297644-?	rs2297644	0	2297644	non_coding_transcript_exon_variant	0	NR	1e-12	12	(Gln, His)	0.15	[0.11-0.19] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	16q22.2	16	71600908	TAT	TAT-AS1 - AC009097.2	ENSG00000260886	ENSG00000260593		22721	22800	rs4788815-?	rs4788815	0	4788815	intergenic_variant	1	NR	2e-17	16.698970004336	(Phe, Tyr)	0.15	[0.11-0.19] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	17p13.1	17	7239532	SLC2A4	PHF23			ENSG00000040633	NA	NA	rs117616209-?	rs117616209	0	117616209	intron_variant	0	NR	3e-14	13.5228787452803	(Fischer's ratio)	0.51	[0.37-0.65] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	22q11.21	22	19167009	SLC25A1	GSC2 - LINC01311	ENSG00000063515	ENSG00000260924		16726	4386	rs807669-?	rs807669	0	807669	intergenic_variant	1	NR	3e-16	15.5228787452803	(Citrate)	0.14	[0.1-0.18] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-?	rs1260326	0	1260326	missense_variant	0	NR	3e-18	17.5228787452803	(Ala, Gln)	0.15	[0.11-0.19] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	2q31.1	2	168906638	G6PC2	SPC25, SPC25, G6PC2, G6PC2			ENSG00000152253, ENSG00000277909, ENSG00000152254, ENSG00000278373	NA	NA	rs560887-?	rs560887	0	560887	intron_variant	0	NR	2e-17	16.698970004336	(Glc)	0.15	[0.11-0.19] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	4q35.2	4	186231173	KLKB1	KLKB1			ENSG00000164344	NA	NA	rs4241816-?	rs4241816	0	4241816	intron_variant	0	NR	6e-13	12.2218487496164	(His, Val)	0.12	[0.081-0.159] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	6q21	6	111473206	SLC16A10	REV3L			ENSG00000009413	NA	NA	rs6900341-?	rs6900341	0	6900341	intron_variant	0	NR	4e-15	14.397940008672	(Ala, Tyr)	0.13	[0.091-0.169] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	11q14.3	11	92975544	MTNR1B	MTNR1B			ENSG00000134640	NA	NA	rs10830963-?	rs10830963	0	10830963	intron_variant	0	NR	3e-11	10.5228787452803	(Glc)	0.14	[0.1-0.18] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Metabolite levels	8,330 European ancestry individuals	NA	12q13.3	12	56471272	GLS2	AC097104.1, GLS2, SPRYD4			ENSG00000285528, ENSG00000135423, ENSG00000176422	NA	NA	rs2638315-?	rs2638315	0	2638315	3_prime_UTR_variant	0	NR	2e-35	34.698970004336	(Gln, Glc)	0.29	[0.25-0.33] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	11q13.3	11	68794860	CPT1A	CPT1A			ENSG00000110090	NA	NA	rs17610395-?	rs17610395	1	2229738	missense_variant	0	NR	8e-12	11.0969100130081	(LA/PUFA)	0.17	[0.13-0.21] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	1p32.2	1	55650832	PCSK9	AL603840.1			ENSG00000234810	NA	NA	rs72669744-?	rs72669744	0	72669744	intron_variant	0	NR	1e-19	19	(L-LDL-FC)	0.59	[0.47-0.71] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	1p31.3	1	62503731	ANGPTL3	DOCK7			ENSG00000116641	NA	NA	rs1168029-?	rs1168029	0	1168029	intron_variant	0	NR	3e-13	12.5228787452803	(MobCH)	0.13	[0.091-0.169] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	7q11.23	7	73596112	MLXIPL	MLXIPL			ENSG00000009950	NA	NA	rs13247874-?	rs13247874	0	13247874	intron_variant	0	NR	8e-14	13.0969100130081	(VLDL-D)	0.16	[0.12-0.2] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	8p21.3	8	20054859	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		87600	24255	rs115849089-?	rs115849089	0	115849089	intergenic_variant	1	NR	4e-15	14.397940008672	(M-VLDL-PL)	0.22	[0.16-0.28] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	9q31.1	9	104903458	ABCA1	ABCA1			ENSG00000165029	NA	NA	rs2575876-?	rs2575876	0	2575876	intron_variant	0	NR	2e-11	10.698970004336	(Tot-C/Est-C)	0.14	[0.1-0.18] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	11q12.2	11	61803311	FADS1, FADS2, FADS3	FADS2, FADS1			ENSG00000134824, ENSG00000149485	NA	NA	rs174547-?	rs174547	0	174547	intron_variant	0	NR	8e-262	261.096910013008	(LA/PUFA)	0.57	[0.53-0.61] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	11q23.3	11	116791863	APOA1, APOC3, APOA4, APOA5	APOA5			ENSG00000110243	NA	NA	rs651821-?	rs651821	0	651821	5_prime_UTR_variant	0	NR	8e-20	19.0969100130081	(Val/serum TG)	0.27	[0.21-0.33] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	15q21.3	15	58388444	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs35853021-?	rs35853021	0	35853021	intron_variant	0	NR	7e-76	75.1549019599858	(XL-HDL-TG)	0.31	[0.27-0.35] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	16p13.11	16	15054789	PDXC1, C20:2, C20:3	NTAN1, NTAN1, PDXDC1			ENSG00000275779, ENSG00000157045, ENSG00000179889	NA	NA	rs11075253-?	rs11075253	0	11075253	intron_variant	0	NR	5e-15	14.301029995664	(LA/PUFA)	0.14	[0.1-0.18] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-?	rs3764261	0	3764261	regulatory_region_variant	1	NR	1e-36	36	(HDL-C)	0.22	[0.18-0.26] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	18q21.1	18	49634444	LIPG	LIPG - SMUG1P1	ENSG00000101670	ENSG00000267444		35259	15906	rs7228085-?	rs7228085	0	7228085	intergenic_variant	1	NR	7e-11	10.1549019599857	(XL-HDL-TG)	0.11	[0.071-0.149] unit increase	Illumina [~ 7700000] (imputed)	N
2008-06-16	18372905	Tomlinson IP	2008-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18372905	A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.	Colorectal cancer	922 European ancestry cases, 927 European ancestry controls	17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls	8q24.21	8	127401060	intergenic	PCAT1, CCAT2, POU5F1B, CASC8			ENSG00000253438, ENSG00000280997, ENSG00000212993, ENSG00000246228	NA	NA	rs6983267-?	rs6983267	0	6983267	non_coding_transcript_exon_variant	0	0.48	7e-11	10.1549019599857		1.24	[1.17-1.33]	Illumina [547647]	N
2008-06-16	18372905	Tomlinson IP	2008-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18372905	A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.	Colorectal cancer	922 European ancestry cases, 927 European ancestry controls	17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls	8q23.3	8	116618444	EIF3H	AC105177.1 - EIF3H	ENSG00000253672	ENSG00000147677		214687	23686	rs16892766-A	rs16892766	0	16892766	intergenic_variant	1	0.07	3e-18	17.5228787452803		1.27	[1.20-1.34]	Illumina [547647]	N
2008-06-16	18372905	Tomlinson IP	2008-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18372905	A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.	Colorectal cancer	922 European ancestry cases, 927 European ancestry controls	17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls	18q21.1	18	48927093	SMAD7	SMAD7			ENSG00000101665	NA	NA	rs4939827-?	rs4939827	0	4939827	intron_variant	0	0.53	2e-06	5.69897000433602		1.18	[1.10-1.25]	Illumina [547647]	N
2008-06-16	18372905	Tomlinson IP	2008-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18372905	A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.	Colorectal cancer	922 European ancestry cases, 927 European ancestry controls	17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls	15q13.3	15	32702555	intergenic	SCG5 - AC090877.2	ENSG00000166922	ENSG00000259721		5457	14715	rs4779584-?	rs4779584	0	4779584	intergenic_variant	1	0.19	5e-07	6.30102999566398		1.23	[1.14-1.34]	Illumina [547647]	N
2008-06-16	18372905	Tomlinson IP	2008-03-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18372905	A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.	Colorectal cancer	922 European ancestry cases, 927 European ancestry controls	17,089 European ancestry cases, 16,862 European ancestry controls, 783 cases, 664 controls	10p14	10	8659256	intergenic	RNA5SP299 - AL355333.1	ENSG00000212505	ENSG00000270234		2425	64754	rs10795668-A	rs10795668	0	10795668	intergenic_variant	1	0.67	3e-13	12.5228787452803		1.12	[1.10-1.16]	Illumina [547647]	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	19p13.2	19	11077477	LDLR	SMARCA4			ENSG00000127616	NA	NA	rs55791371-?	rs55791371	0	55791371	intron_variant	0	NR	8e-17	16.0969100130081	(M-LDL-C/M-LDL-PL)	0.26	[0.2-0.32] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	19q13.32	19	44908822	APOC2, APOE, APOC1	APOE			ENSG00000130203	NA	NA	rs7412-?	rs7412	0	7412	missense_variant	0	NR	3e-58	57.5228787452803	(L-LDL-FC)	0.75	[0.65-0.85] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	20q13.12	20	45906012	PLTP	PLTP			ENSG00000100979	NA	NA	rs6065904-?	rs6065904	0	6065904	intron_variant	0	NR	2e-31	30.698970004336	(L-HDL-L/M-HDL-L)	0.22	[0.18-0.26] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	1q23.3	1	161571067	FCGR2A, FCGR2B	AL590385.2			ENSG00000273112	NA	NA	rs67418890-?	rs67418890	0	67418890	intron_variant	0	NR	1e-10	10	(XL-HDL-CE)	0.19	[0.13-0.25] unit increase	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	4q13.3	4	72456848	ALB	ADAMTS3			ENSG00000156140	NA	NA	rs115136538-?	rs115136538	0	115136538	intron_variant	0	NR	5e-18	17.301029995664	(Albumin)	0.51	[0.39-0.63] unit decrease	Illumina [~ 7700000] (imputed)	N
2012-02-28	22286219	Kettunen J	2012-01-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22286219	Genome-wide association study identifies multiple loci influencing human serum metabolite levels.	Lipid metabolism phenotypes	8,330 European ancestry individuals	NA	6p22.1	6	30049294	PPP1R11	ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP, ZNRD1ASP			ENSG00000204623, ENSG00000236598, ENSG00000235394, ENSG00000196299, ENSG00000225618, ENSG00000235814, ENSG00000229653, ENSG00000232691	NA	NA	rs6917603-?	rs6917603	0	6917603	intron_variant	0	NR	3e-29	28.5228787452803	(XXL-VLDL-P)	0.24	[0.2-0.28] unit decrease	Illumina [~ 7700000] (imputed)	N
2008-06-16	17158188	Bierut LJ	2006-12-07	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Nicotine dependence	482 European ancestry cases, 466 European ancestry controls	568 European ancestry cases, 413 European ancestry controls	21q22.2	21	39008323	NR	AF064858.1			ENSG00000235888	NA	NA	rs2836823-T	rs2836823	0	2836823	intron_variant	0	0.40	2e-06	5.69897000433602		1.46	[1.23-1.73]	Perlegen [2400000]	N
2008-06-16	17158188	Bierut LJ	2006-12-07	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Nicotine dependence	482 European ancestry cases, 466 European ancestry controls	568 European ancestry cases, 413 European ancestry controls	10q21.3	10	66881193	CTNNA3	CTNNA3			ENSG00000183230	NA	NA	rs4142041-G	rs4142041	0	4142041	intron_variant	0	0.34	6e-06	5.22184874961636		1.14	[0.97-1.35]	Perlegen [2400000]	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	17q25.3	17	78308429	BIRC5, SOCS3	LINC01993 - AC087645.2	ENSG00000204277	ENSG00000267737		29937	7300	rs8081523-?	rs8081523	0	8081523	regulatory_region_variant	1	NR	5e-06	5.30102999566398		0.13	[0.075-0.185] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	5q14.1	5	79020653	BHMT2, BHMT, DMGDH	DMGDH			ENSG00000132837	NA	NA	rs921943-T	rs921943	0	921943	intron_variant	0	NR	9e-28	27.0457574905607		0.246	[0.20-0.29] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	2q35	2	215995827	MREG	MREG			ENSG00000118242	NA	NA	rs3770549-?	rs3770549	0	3770549	intron_variant	0	NR	3e-06	5.52287874528034		0.161	[0.092-0.230] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	6q24.1	6	139510043	CITED2	AL592429.2			ENSG00000226571	NA	NA	rs679582-?	rs679582	0	679582	intron_variant	0	NR	3e-06	5.52287874528034		0.095	[0.056-0.134] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	9p24.2	9	2777384	KIAA0020, KCNV2	PUM3			ENSG00000080608	NA	NA	rs10812641-?	rs10812641	0	10812641	intron_variant	0	NR	3e-06	5.52287874528034		0.091	[0.054-0.128] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	17p11.2	17	21020764	MGC87631, DHRS7B	USP22			ENSG00000124422	NA	NA	rs7226229-?	rs7226229	0	7226229	intron_variant	0	NR	1e-06	6		0.117	[0.070-0.164] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	19q13.33	19	49834979	MED25	MED25			ENSG00000104973	NA	NA	rs2017698-?	rs2017698	0	2017698	splice_region_variant	0	NR	1e-07	7		0.492	[0.31-0.67] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	19q13.42	19	54404500	TTYH1	AC245884.4 - TTYH1	ENSG00000237955	ENSG00000276537		24540	10719	rs11084337-?	rs11084337	0	11084337	intergenic_variant	1	NR	9e-07	6.04575749056067		0.134	[0.081-0.187] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	21q22.3	21	43058387	CBS	CBS			ENSG00000160200	NA	NA	rs6586282-?	rs6586282	0	6586282	intron_variant	0	NR	5e-06	5.30102999566398		0.117	[0.068-0.166] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Se levels)	5477 European ancestry individuals	NA	5q14.1	5	79118514	BHMT2, BHMT, DMGDH	DMGDH, BHMT			ENSG00000132837, ENSG00000145692	NA	NA	rs506500-?	rs506500	0	506500	intron_variant	0	NR	8e-12	11.0969100130081	(Conditioned on rs921943)	NA		Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	1p36.32	1	3774964	CCDC27, LOC388588, KIAA0562, DFFB, LRRC47	SMIM1			ENSG00000235169	NA	NA	rs1175550-A	rs1175550	0	1175550	intron_variant	0	NR	5e-10	9.30102999566398		0.198	[0.14-0.26] unit decrease	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	1q21.3	1	151372265	PSMB4, POGZ, SELENBP1	SELENBP1			ENSG00000143416	NA	NA	rs2769264-G	rs2769264	0	2769264	intron_variant	0	NR	3e-20	19.5228787452803		0.313	[0.25-0.38] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	3q11.2	3	97449896	EPHA6	EPHA6			ENSG00000080224	NA	NA	rs1458303-?	rs1458303	0	1458303	intron_variant	0	NR	3e-07	6.52287874528034		2.978	[1.84-4.12] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	4q25	4	113027634	ANK2	AC093879.1, ANK2			ENSG00000248152, ENSG00000145362	NA	NA	rs10014072-?	rs10014072	0	10014072	intron_variant	0	NR	1e-06	6		0.164	[0.097-0.231] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	5q14.3	5	85287951	COX7C, EDIL3	AC117522.1 - AC010486.1	ENSG00000248170	ENSG00000248667		49877	132077	rs12153606-?	rs12153606	0	12153606	intergenic_variant	1	NR	2e-06	5.69897000433602		0.159	[0.092-0.226] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	6q12	6	66219155	EGFL11	NUFIP1P1 - AL450336.1	ENSG00000218890	ENSG00000270521		124246	491087	rs3857536-?	rs3857536	0	3857536	intergenic_variant	1	NR	4e-06	5.39794000867204		0.129	[0.074-0.184] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Cu levels)	2,603 European ancestry individuals	NA	12q21.2	12	75670748	KRR1, PHLDA1	AC078820.2, AC078923.1			ENSG00000286259, ENSG00000258077	NA	NA	rs12582659-?	rs12582659	0	12582659	intron_variant	0	NR	3e-06	5.52287874528034		1.262	[0.73-1.79] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	8q21.2	8	85356084	CA1, CA2, CA3, CA13	CA1			ENSG00000133742	NA	NA	rs1532423-A	rs1532423	0	1532423	intron_variant	0	NR	6e-12	11.2218487496164		0.178	[0.13-0.23] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	15q24.2	15	75041843	SCAMP5, PPCDC	PPCDC			ENSG00000138621	NA	NA	rs2120019-C	rs2120019	0	2120019	intron_variant	0	NR	2e-18	17.698970004336		0.287	[0.22-0.35] unit decrease	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	Xp11.21	X	56785262	KLF8, ZXDA, ZXDB	NBDY			ENSG00000204272	NA	NA	rs4826508-T	rs4826508	0	4826508	intron_variant	0	NR	1e-12	12		0.21	[0.15-0.27] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	2q23.3	2	153712244	RPRM, GALNT13	AC012501.2 - DNAJA1P2	ENSG00000227400	ENSG00000236917		118956	49206	rs10931753-?	rs10931753	0	10931753	intergenic_variant	1	NR	5e-06	5.30102999566398		0.129	[0.074-0.184] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	3q11.2	3	96681755	EPHA6	RPL18AP8 - RCC2P5	ENSG00000218754	ENSG00000241018		61924	71430	rs6793516-?	rs6793516	0	6793516	intergenic_variant	1	NR	5e-06	5.30102999566398		2.372	[1.36-3.39] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	4p16.2	4	5928306	CRMP1, FLJ46481	C4orf50			ENSG00000181215	NA	NA	rs4333127-?	rs4333127	0	4333127	intron_variant	0	NR	3e-06	5.52287874528034		0.218	[0.13-0.31] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	7p21.2	7	15591246	MEOX2	AGMO - MEOX2	ENSG00000187546	ENSG00000106511		29231	19966	rs11763353-?	rs11763353	0	11763353	intergenic_variant	1	NR	7e-07	6.15490195998574		0.192	[0.12-0.27] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	11q14.1	11	81217766	intergenic	AP003464.1			ENSG00000287912	NA	NA	rs11232535-?	rs11232535	0	11232535	intron_variant	0	NR	7e-07	6.15490195998574		0.325	[0.20-0.45] unit increase	Illumina [> 2500000] (imputed)	N
2008-09-12	18758464	Kugathasan S	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758464	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Inflammatory bowel disease	1,011 European ancestry cases, 4,250 European ancestry controls	1,922 European ancestry cases, 14,124 European ancestry controls	20q13.33	20	63712604	TNFRSF6B	ZGPAT, AL121845.3			ENSG00000197114, ENSG00000273154	NA	NA	rs2315008-G	rs2315008	0	2315008	intron_variant	0	0.69	9e-15	14.0457574905607		1.36	[1.05-1.76]	Illumina [NR]	N
2008-09-12	18758464	Kugathasan S	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758464	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Inflammatory bowel disease	1,011 European ancestry cases, 4,250 European ancestry controls	1,922 European ancestry cases, 14,124 European ancestry controls	16q12.1	16	50722863	NOD2	NOD2			ENSG00000167207	NA	NA	rs5743289-T	rs5743289	0	5743289	intron_variant	0	0.17	4e-10	9.39794000867204		1.46	[1.29-1.64]	Illumina [NR]	N
2008-09-12	18758464	Kugathasan S	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758464	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Inflammatory bowel disease	1,011 European ancestry cases, 4,250 European ancestry controls	1,922 European ancestry cases, 14,124 European ancestry controls	6p21.32	6	32601914	HLA-DQA1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		12066	26265	rs477515-?	rs477515	0	477515	intron_variant	1	0.69	1e-08	8		1.38	[1.23-1.54]	Illumina [NR]	N
2008-09-12	18758464	Kugathasan S	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758464	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Inflammatory bowel disease	1,011 European ancestry cases, 4,250 European ancestry controls	1,922 European ancestry cases, 14,124 European ancestry controls	9q32	9	114806486	TNFSF15	TNFSF15 - AL133412.1	ENSG00000181634	ENSG00000229817		447	39108	rs6478109-?	rs6478109	0	6478109	TF_binding_site_variant	1	0.69	3e-08	7.52287874528034		1.36	[1.22-1.52]	Illumina [NR]	N
2008-09-12	18758464	Kugathasan S	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758464	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Inflammatory bowel disease	1,011 European ancestry cases, 4,250 European ancestry controls	1,922 European ancestry cases, 14,124 European ancestry controls	21q22.2	21	39093608	PSMG1	AF064858.1 - RPL23AP12	ENSG00000235888	ENSG00000228861		30714	33960	rs2836878-?	rs2836878	0	2836878	intergenic_variant	1	0.72	4e-12	11.397940008672		1.41	[1.08-1.84]	Illumina [NR]	N
2008-09-12	18758464	Kugathasan S	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758464	Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.	Inflammatory bowel disease	1,011 European ancestry cases, 4,250 European ancestry controls	1,922 European ancestry cases, 14,124 European ancestry controls	1p31.3	1	67240275	IL23R	IL23R			ENSG00000162594	NA	NA	rs11209026-?	rs11209026	0	11209026	missense_variant	0	0.94	7e-11	10.1549019599857		2.56	[1.92-3.45]	Illumina [NR]	N
2008-09-03	18846228	Weidinger S	2008-08-22	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18846228	Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.	IgE levels	1,530 European ancesrty individuals	9,769 European ancestry individuals	1q23.2	1	159302270	FCER1A	FCER1A			ENSG00000179639	NA	NA	rs2251746-C	rs2251746	0	2251746	intron_variant	0	0.26	2e-20	19.698970004336		19.2	[NR] % decrease	Affymetrix [353569]	N
2008-09-03	18846228	Weidinger S	2008-08-22	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18846228	Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.	IgE levels	1,530 European ancesrty individuals	9,769 European ancestry individuals	5q31.1	5	132637485	RAD50	AC116366.3, TH2LCRR, RAD50			ENSG00000283782, ENSG00000223442, ENSG00000113522	NA	NA	rs2040704-?	rs2040704	0	2040704	intron_variant	0	0.23	4e-08	7.39794000867204		13.9	[NR] % increase	Affymetrix [353569]	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	14q23.3	14	65006478	MAX, FNTB	MAX, FNTB, CHURC1-FNTB			ENSG00000125952, ENSG00000257365, ENSG00000125954	NA	NA	rs7148590-?	rs7148590	0	7148590	intron_variant	0	NR	1e-07	7		0.14	[0.089-0.191] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	14q31.3	14	86350752	FLRT2	LINC02309			ENSG00000258994	NA	NA	rs10484100-?	rs10484100	0	10484100	intron_variant	0	NR	3e-06	5.52287874528034		0.209	[0.12-0.30] unit increase	Illumina [> 2500000] (imputed)	N
2013-11-20	23720494	Evans DM	2013-05-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23720494	Genome-wide association study identifies loci affecting blood copper, selenium and zinc.	Blood trace element (Zn levels)	2,603 European ancestry individuals	NA	18q12.3	18	41648346	PIK3C3	AC021504.1 - NPM1P1	ENSG00000267313	ENSG00000267652		16161	140816	rs9958032-?	rs9958032	0	9958032	intergenic_variant	1	NR	3e-06	5.52287874528034		1.467	[0.85-2.08] unit increase	Illumina [> 2500000] (imputed)	N
2008-09-03	18591461	Turner ST	2008-06-30	Hypertension	www.ncbi.nlm.nih.gov/pubmed/18591461	Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic.	Response to diuretic therapy	97 African American good response individuals, 97 African American poor response individuals, 98 European ancestry good response individuals, 97 European ancestry poor response individuals	NA	12q15	12;12;12	69333410;69430244;69369207	FRS2, LYZ, YEATS4	AC020656.2 - LYZ; RPS26P45 - LINC02373; YEATS4				NA	NA	rs317689-?; rs7297610-?; rs315135-?	rs317689; rs7297610; rs315135	0	NA	intergenic_variant; intergenic_variant; intron_variant	NA	NR	3e-07	6.52287874528034	(blacks)	NA		Affymetrix [up to 102334]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	12q24.22	12	116564853	KRTHB5	MAP1LC3B2			ENSG00000258102	NA	NA	rs2089222-A	rs2089222	0	2089222	intron_variant	0	0.03	8e-08	7.09691001300806		2.26	[1.60-3.0]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	1q43	1	237103303	RYR2	RYR2			ENSG00000198626	NA	NA	rs7554607-A	rs7554607	0	7554607	intron_variant	0	0.56	2e-06	5.69897000433602		1.49	[1.20-1.70]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	3q26.32	3	178712151	KCNMB2	KCNMB2-AS1, KCNMB2, AC117457.1			ENSG00000237978, ENSG00000197584, ENSG00000275163	NA	NA	rs9290663-T	rs9290663	0	9290663	intron_variant	0	0.13	6e-06	5.22184874961636		1.58	[1.20-1.90]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	12p13.32	12	4315956	C12orf5	TIGAR, AC008012.1			ENSG00000078237, ENSG00000285901	NA	NA	rs10849033-G	rs10849033	0	10849033	intron_variant	0	0.02	9e-06	5.04575749056067		2.55	[1.60-3.80]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	10q21.2	10	61963818	ARID5B	ARID5B			ENSG00000150347	NA	NA	rs10821936-C	rs10821936	1	10821936	intron_variant	0	0.34	1e-15	15		1.91	[1.60-2.20]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	7p12.2	7	50398606	DDC, IKZF1	IKZF1, AC124014.1			ENSG00000185811, ENSG00000285165	NA	NA	rs11978267-G	rs11978267	0	11978267	intron_variant	0	0.27	8e-11	10.0969100130081		1.69	[1.40-1.90]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	6q24.1	6	140848688	intergenic	AL035446.2, AL035446.1			ENSG00000285875, ENSG00000234147	NA	NA	rs11155133-G	rs11155133	0	11155133	intron_variant	0	0.01	3e-07	6.52287874528034		3.62	[2.10-6.00]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	19q13.31	19	44007237	ZNF230	ZNF230			ENSG00000159882	NA	NA	rs2191566-G	rs2191566	0	2191566	intron_variant	0	0.28	4e-07	6.39794000867204		1.52	[1.20-1.70]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	1p31.1	1	76306643	SIAT7C	ST6GALNAC3			ENSG00000184005	NA	NA	rs10873876-T	rs10873876	0	10873876	intron_variant	0	0.15	4e-06	5.39794000867204		1.55	[1.20-1.80]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	1q31.3	1	196875463	intergenic	BX248415.1			ENSG00000285986	NA	NA	rs6428370-G	rs6428370	0	6428370	intron_variant	0	0.32	7e-06	5.15490195998574		1.43	[1.20-1.60]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	1q44	1	247526230	OR2C3	OR2C3, GCSAML-AS1, GCSAML			ENSG00000196242, ENSG00000284824, ENSG00000169224	NA	NA	rs1881797-C	rs1881797	0	1881797	3_prime_UTR_variant	0	0.18	7e-06	5.15490195998574		1.52	[1.20-1.80]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	18p11.32	18	2498055	intergenic	AP005230.1 - AP005136.4	ENSG00000263745	ENSG00000286975		8629	8573	rs1879352-C	rs1879352	0	1879352	intergenic_variant	1	0.16	9e-06	5.04575749056067		1.53	[1.20-1.80]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	10p11.21	10	34529060	PARD3	PARD3			ENSG00000148498	NA	NA	rs563507-A	rs563507	0	563507	intron_variant	0	0.04	9e-06	5.04575749056067		2	[1.40-2.70]	Affymetrix [307944]	N
2009-09-11	19684603	Trevino LR	2009-08-16	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19684603	Germline genomic variants associated with childhood acute lymphoblastic leukemia.	Acute lymphoblastic leukemia (childhood)	317 European ancestry cases, 17,958 European ancestry controls	NA	2q36.1	2	223053265	KCNE4	KCNE4			ENSG00000152049	NA	NA	rs12621643-T	rs12621643	0	12621643	missense_variant	0	0.28	3e-06	5.52287874528034		1.48	[1.20-1.70]	Affymetrix [307944]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	9p24.1	9	5893861	MLANA	MLANA, KIAA2026			ENSG00000120215, ENSG00000183354	NA	NA	rs2150702-G	rs2150702	0	2150702	intron_variant	0	0.49	3e-08	7.52287874528034		1.16	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	2p21	2	43098432	THADA	LINC02580			ENSG00000230587	NA	NA	rs6718520-A	rs6718520	0	6718520	intron_variant	0	0.48	3e-08	7.52287874528034		1.17	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	1p13.1	1	116561593	CD58	CD58			ENSG00000116815	NA	NA	rs2300747-A	rs2300747	0	2300747	intron_variant	0	0.91	6e-09	8.22184874961636		1.37	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	6p21.32	6	32445768	HLA-DRB1	HLA-DRA - HLA-DRB9	ENSG00000234794	ENSG00000226035		722	14053	rs3129889-G	rs3129889	0	3129889	intergenic_variant	1	0.20	1e-206	206		2.97	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	17q21.2	17	42329511	STAT3	STAT3			ENSG00000168610	NA	NA	rs2293152-C	rs2293152	0	2293152	intron_variant	0	0.62	4e-08	7.39794000867204		1.22	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	20q13.12	20	46111557	CD40	RPL13P2 - CD40	ENSG00000213820	ENSG00000101017		11381	6721	rs6074022-C	rs6074022	0	6074022	TF_binding_site_variant	1	0.27	5e-06	5.30102999566398		1.15	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	5q33.3	5	159332892	IL12B	AC008691.1			ENSG00000249738	NA	NA	rs2546890-A	rs2546890	0	2546890	non_coding_transcript_exon_variant	0	0.52	8e-08	7.09691001300806		1.16	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	17q21.32	17	47691470	KPNB1, TBX21, TBKBP1	KPNB1 - TBKBP1	ENSG00000108424	ENSG00000198933		5965	2611	rs8070463-T	rs8070463	0	8070463	intergenic_variant	1	0.50	1e-07	7		1.15	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	3q13.33	3	122050675	ILDR1, CD86	Y_RNA - CD86	ENSG00000265852	ENSG00000114013		25371	4687	rs2681424-T	rs2681424	0	2681424	intergenic_variant	1	0.40	2e-07	6.69897000433602		1.16	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	6q25.3	6	159044945	TAGAP	AL035530.1, AL035530.2, TAGAP			ENSG00000226032, ENSG00000271913, ENSG00000164691	NA	NA	rs1738074-C	rs1738074	0	1738074	5_prime_UTR_variant	0	0.58	4e-07	6.39794000867204		1.15	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	10q22.3	10	79274913	ZMIZ1	ZMIZ1			ENSG00000108175	NA	NA	rs1250542-A	rs1250542	0	1250542	intron_variant	0	0.37	4e-07	6.39794000867204		1.15	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	16p13.13	16	11312946	TNP2, PRM3, PRM2, PRM1, C16orf75	RMI2			ENSG00000175643	NA	NA	rs7191700-C	rs7191700	0	7191700	intron_variant	0	0.67	6e-07	6.22184874961636		1.15	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	13q14.2	13	50268304	intergenic	DLEU1			ENSG00000176124	NA	NA	rs9596270-T	rs9596270	0	9596270	intron_variant	0	0.93	7e-07	6.15490195998574		1.35	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	5q33.3	5	159491886	IL12B	AC008691.1, AC008703.1			ENSG00000249738, ENSG00000283413	NA	NA	rs10866713-A	rs10866713	0	10866713	intron_variant	0	0.22	7e-07	6.15490195998574		1.17	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	3p24.1	3	28037594	EOMES	LINC01967			ENSG00000235493	NA	NA	rs170934-T	rs170934	0	170934	intron_variant	0	0.48	2e-08	7.69897000433602		1.17	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	6p22.1	6	29952555	HLA-B	HLA-A - HLA-W	ENSG00000235657	ENSG00000235144		6671	4041	rs9260489-T	rs9260489	0	9260489	intron_variant	1	0.45	1e-11	11		1.21	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	10p15.1	10	6060049	IL2RA	IL2RA			ENSG00000134460	NA	NA	rs12722489-C	rs12722489	0	12722489	intron_variant	0	0.85	4e-08	7.39794000867204		1.23	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	19p13.11	19	16437564	EPS15L1	EPS15L1			ENSG00000127527	NA	NA	rs10411936-A	rs10411936	0	10411936	intron_variant	0	0.30	2e-07	6.69897000433602		1.16	[NR]	Affymetrix, Illumina [2529394]	N
2012-01-17	22190364	Patsopoulos NA	2011-12-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/22190364	Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.	Multiple sclerosis	5,545 European ancestry cases, 12,153 European ancestry controls	NA	2p13.3	2	68419651	FBXO48, C2orf13, PLEK	PLEK - AC127383.1	ENSG00000115956	ENSG00000229462		22198	26059	rs7592330-A	rs7592330	0	7592330	regulatory_region_variant	1	0.56	2e-07	6.69897000433602		1.15	[NR]	Affymetrix, Illumina [2529394]	N
2008-06-11	17362836	Schymick JC	2007-02-20	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17362836	Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.	Amyotrophic lateral sclerosis	276 European ancestry cases, 271 European ancestry controls	NA	2p24.2	2	18053180	intergenic	KCNS3			ENSG00000170745	NA	NA	rs16984239-?	rs16984239	0	16984239	intron_variant	0	NR	2e-06	5.69897000433602		2.1	[1.50-3.00]	Illumina [549062]	N
2008-06-11	17362836	Schymick JC	2007-02-20	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17362836	Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.	Amyotrophic lateral sclerosis	276 European ancestry cases, 271 European ancestry controls	NA	4q31.3	4	152972202	KIAA1727	FHDC1			ENSG00000137460	NA	NA	rs11099864-?	rs11099864	0	11099864	intron_variant	0	NR	9e-06	5.04575749056067		1	[0.80-1.40]	Illumina [549062]	N
2008-06-11	17362836	Schymick JC	2007-02-20	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17362836	Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.	Amyotrophic lateral sclerosis	276 European ancestry cases, 271 European ancestry controls	NA	10q26.2	10	127476239	intergenic	DOCK1 - NPS	ENSG00000150760	ENSG00000214285		23722	73130	rs4363506-?	rs4363506	0	4363506	intergenic_variant	1	NR	7e-07	6.15490195998574		1.9	[1.50-2.40]	Illumina [549062]	N
2008-06-11	17362836	Schymick JC	2007-02-20	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17362836	Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.	Amyotrophic lateral sclerosis	276 European ancestry cases, 271 European ancestry controls	NA	8q24.23	8	135859496	intergenic	LINC02055			ENSG00000254101	NA	NA	rs12680546-?	rs12680546	0	12680546	non_coding_transcript_exon_variant	0	NR	3e-06	5.52287874528034		1.67	[1.25-2.00]	Illumina [549062]	N
2008-06-11	17362836	Schymick JC	2007-02-20	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17362836	Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.	Amyotrophic lateral sclerosis	276 European ancestry cases, 271 European ancestry controls	NA	20q13.2	20	52086094	ZFP64	ZFP64, AL109984.1			ENSG00000020256, ENSG00000287511	NA	NA	rs6013382-?	rs6013382	0	6013382	intron_variant	0	NR	5e-06	5.30102999566398		1.43	[1.11-1.67]	Illumina [549062]	N
2008-06-11	17362836	Schymick JC	2007-02-20	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17362836	Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data.	Amyotrophic lateral sclerosis	276 European ancestry cases, 271 European ancestry controls	NA	9q31.3	9	112087910	SUSD1	SUSD1			ENSG00000106868	NA	NA	rs2782931-?	rs2782931	0	2782931	intron_variant	0	NR	6e-06	5.22184874961636		1.11	[0.91-1.43]	Illumina [549062]	N
2012-01-19	22205951	Kerner B	2011-12-21	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22205951	Genome-wide association study in bipolar patients stratified by co-morbidity.	Bipolar disorder	1,000 European ancestry cases, 1,034 European ancestry controls	NA	6q27	6	165741969	RP11-252P19.1	PDE10A			ENSG00000112541	NA	NA	rs1039002-?	rs1039002	0	1039002	intron_variant	0	NR	2e-08	7.69897000433602	(Latent Class 1)	NA		Affymetrix [728331]	N
2012-01-19	22205951	Kerner B	2011-12-21	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22205951	Genome-wide association study in bipolar patients stratified by co-morbidity.	Bipolar disorder	1,000 European ancestry cases, 1,034 European ancestry controls	NA	1q41	1	220484892	MARK1	PRELID3BP1 - LINC02779	ENSG00000226226	ENSG00000231529		16084	212	rs12563333-?	rs12563333	0	12563333	intergenic_variant	1	NR	6e-08	7.22184874961636	(Latent Class 1)	NA		Affymetrix [728331]	N
2012-01-19	22205951	Kerner B	2011-12-21	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22205951	Genome-wide association study in bipolar patients stratified by co-morbidity.	Bipolar disorder	1,000 European ancestry cases, 1,034 European ancestry controls	NA	3p26.3	3	1856289	intergenic	RPL23AP39 - RPL21P17	ENSG00000214074	ENSG00000214073		125815	49362	rs2727943-?	rs2727943	0	2727943	intergenic_variant	1	NR	3e-08	7.52287874528034	(Latent Class 2)	NA		Affymetrix [728331]	N
2013-07-01	23493294	Gao X	2013-03-14	Invest Ophthalmol Vis Sci	www.ncbi.nlm.nih.gov/pubmed/23493294	A genome-wide association study of central corneal thickness in Latinos.	Central corneal thickness	1,644 Latino individuals	124 Latino individuals	9q34.3	9	134548682	COL5A1, RXRA	AL669970.3 - AL669970.2	ENSG00000228877	ENSG00000227150		3438	4056	rs1536482-G	rs1536482	0	1536482	regulatory_region_variant	1	0.73	6e-08	7.22184874961636		0.22	unit decrease	Illumina [6290547] (imputed)	N
2013-07-01	23493294	Gao X	2013-03-14	Invest Ophthalmol Vis Sci	www.ncbi.nlm.nih.gov/pubmed/23493294	A genome-wide association study of central corneal thickness in Latinos.	Central corneal thickness	1,644 Latino individuals	124 Latino individuals	9q34.3	9	134544468	COL5A1, RXRA, LOC100506532	AL669970.3			ENSG00000228877	NA	NA	rs3118515-A	rs3118515	0	3118515	intron_variant	0	0.262	8e-10	9.09691001300806		0.23	[NR] unit decrease	Illumina [6290547] (imputed)	N
2008-09-03	18758461	Di Bernardo MC	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758461	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	Chronic lymphocytic leukemia	505 European ancestry cases, 1,438 European ancestry controls	1,024 European ancestry cases, 1,677 European ancestry controls	15q23	15	69726651	intergenic	DRAIC			ENSG00000245750	NA	NA	rs7176508-A	rs7176508	0	7176508	intron_variant	0	0.37	5e-12	11.301029995664		1.37	[1.26-1.50]	Illumina [345665]	N
2008-09-03	18758461	Di Bernardo MC	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758461	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	Chronic lymphocytic leukemia	505 European ancestry cases, 1,438 European ancestry controls	1,024 European ancestry cases, 1,677 European ancestry controls	2q13	2	111039881	ACOXL, BCL2L11	MIR4435-2HG, ACOXL			ENSG00000172965, ENSG00000153093	NA	NA	rs17483466-G	rs17483466	0	17483466	intron_variant	0	0.20	2e-10	9.69897000433602		1.39	[1.25-1.53]	Illumina [345665]	N
2008-09-03	18758461	Di Bernardo MC	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758461	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	Chronic lymphocytic leukemia	505 European ancestry cases, 1,438 European ancestry controls	1,024 European ancestry cases, 1,677 European ancestry controls	19q13.32	19	46704397	PRKD2, STRN4	PRKD2			ENSG00000105287	NA	NA	rs11083846-A	rs11083846	0	11083846	splice_region_variant	0	0.22	4e-09	8.39794000867204		1.35	[1.22-1.49]	Illumina [345665]	N
2008-09-03	18758461	Di Bernardo MC	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758461	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	Chronic lymphocytic leukemia	505 European ancestry cases, 1,438 European ancestry controls	1,024 European ancestry cases, 1,677 European ancestry controls	11q24.1	11	123490689	GRAMD1B	GRAMD1B			ENSG00000023171	NA	NA	rs735665-A	rs735665	0	735665	intron_variant	0	0.21	4e-12	11.397940008672		1.45	[1.31-1.61]	Illumina [345665]	N
2008-09-03	18758461	Di Bernardo MC	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758461	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	Chronic lymphocytic leukemia	505 European ancestry cases, 1,438 European ancestry controls	1,024 European ancestry cases, 1,677 European ancestry controls	6p25.3	6	411064	IRF4	IRF4			ENSG00000137265	NA	NA	rs872071-G	rs872071	0	872071	3_prime_UTR_variant	0	0.54	2e-20	19.698970004336		1.54	[1.41- 1.69]	Illumina [345665]	N
2008-09-03	18758461	Di Bernardo MC	2008-08-31	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18758461	A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.	Chronic lymphocytic leukemia	505 European ancestry cases, 1,438 European ancestry controls	1,024 European ancestry cases, 1,677 European ancestry controls	2q37.1	2	230226508	SP140, SP110	SP140			ENSG00000079263	NA	NA	rs13397985-G	rs13397985	0	13397985	intron_variant	0	0.19	6e-10	9.22184874961636		1.41	[1.26-1.57]	Illumina [345665]	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	10q21.2	10	59653595	SLC16A9	SLC16A9			ENSG00000165449	NA	NA	rs12356193-A	rs12356193	0	12356193	intron_variant	0	0.83	1e-08	8		0.08	[0.051-0.105] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	11q13.1	11	64589600	SLC22A12	SLC22A11 - SLC22A12	ENSG00000168065	ENSG00000197891		16725	1041	rs505802-T	rs505802	0	505802	intergenic_variant	1	0.70	2e-09	8.69897000433602		0.06	[0.038-0.074] mg/dl decrease	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	11q13.1	11	64563990	SLC22A11	SLC22A11			ENSG00000168065	NA	NA	rs17300741-A	rs17300741	0	17300741	intron_variant	0	0.51	7e-14	13.1549019599857		0.06	[0.046-0.078] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	6p22.2	6	25607343	SCGN, LRRC16A	CARMIL1			ENSG00000079691	NA	NA	rs742132-A	rs742132	0	742132	intron_variant	0	0.70	9e-09	8.04575749056067		0.05	[0.036-0.072] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	4q22.1	4	88131171	ABCG2	ABCG2			ENSG00000118777	NA	NA	rs2231142-T	rs2231142	0	2231142	missense_variant	0	0.11	1e-10	10	(women)	0.14	[0.096-0.181] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	6p22.2	6	25823216	SLC17A1	SLC17A1			ENSG00000124568	NA	NA	rs1183201-A	rs1183201	0	1183201	intron_variant	0	0.48	3e-14	13.5228787452803		0.06	[0.459-0.078] mg/dl decrease	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	4p16.1	4	9921380	SLC2A9	SLC2A9			ENSG00000109667	NA	NA	rs734553-T	rs734553	0	734553	intron_variant	0	0.77	1e-192	192	(women)	0.4	[0.371-0.423] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-T	rs780094	0	780094	intron_variant	0	0.42	1e-09	9		0.05	[0.035-0.068] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	4q22.1	4	88131171	ABCG2	ABCG2			ENSG00000118777	NA	NA	rs2231142-T	rs2231142	0	2231142	missense_variant	0	0.11	2e-18	17.698970004336	(men)	0.22	[0.171-0.270] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	1q21.1	1	145709377	PDZK1	PDZK1 - CD160	ENSG00000174827	ENSG00000117281		1229	10094	rs12129861-A	rs12129861	0	12129861	intergenic_variant	1	0.46	3e-09	8.52287874528034		0.06	[0.042-0.083] mg/dl decrease	Affymetrix, Illumina [2493963] (imputed)	N
2009-06-22	19503597	Kolz M	2009-06-05	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/19503597	Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.	Uric acid levels	12,328 European ancestry males, 15,813 European ancestry females	NA	4p16.1	4	9921380	SLC2A9	SLC2A9			ENSG00000109667	NA	NA	rs734553-T	rs734553	0	734553	intron_variant	0	0.77	1e-41	41	(men)	0.22	[0.188-0.252] mg/dl increase	Affymetrix, Illumina [2493963] (imputed)	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	4q35.2	4	186757712	FAT1, MTNR1A	FAT1 - AC108865.1	ENSG00000083857	ENSG00000250829		30990	133257	rs925642-?	rs925642	0	925642	regulatory_region_variant	1	NR	7e-06	5.15490195998574	(obesity)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	7q22.2	7	104863366	LHFPL3	LHFPL3			ENSG00000187416	NA	NA	rs10953454-?	rs10953454	0	10953454	intron_variant	0	NR	7e-07	6.15490195998574	(HIP)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	22q12.1	22	27982484	PITPNB	TTC28, TTC28-AS1			ENSG00000100154, ENSG00000235954	NA	NA	rs5762430-?	rs5762430	0	5762430	synonymous_variant	0	NR	7e-07	6.15490195998574	(HIP)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	16q23.1	16	78918542	WWOX	WWOX			ENSG00000186153	NA	NA	rs9923451-?	rs9923451	0	9923451	intron_variant	0	NR	8e-07	6.09691001300806	(HIP)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	21q21.1	21	21317024	NCAM2	NCAM2			ENSG00000154654	NA	NA	rs11088859-?	rs11088859	0	11088859	intron_variant	0	NR	4e-08	7.39794000867204	(waist)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	2q14.2	2	120437605	INHBB	INHBB - LINC01101	ENSG00000163083	ENSG00000280409		85802	26730	rs7581710-?	rs7581710	0	7581710	regulatory_region_variant	1	NR	2e-07	6.69897000433602	(WHR)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	6q23.2	6	131488780	ARG1	ARG1			ENSG00000118520	NA	NA	rs2807278-?	rs2807278	0	2807278	intron_variant	0	NR	3e-07	6.52287874528034	(WHR)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	14q24.3	14	78319734	NRXN3	NRXN3			ENSG00000021645	NA	NA	rs11624704-?	rs11624704	0	11624704	intron_variant	0	NR	3e-09	8.52287874528034	(WHR)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	8p22	8	18120141	ASAH1	AC124242.3			ENSG00000286542	NA	NA	rs17126232-?	rs17126232	0	17126232	intron_variant	0	NR	8e-08	7.09691001300806	(weight)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	16q12.2	16	53779455	FTO	FTO			ENSG00000140718	NA	NA	rs17817449-?	rs17817449	0	17817449	intron_variant	0	NR	2e-12	11.698970004336	(obesity)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	8p22	8	18120141	ASAH1	AC124242.3			ENSG00000286542	NA	NA	rs17126232-?	rs17126232	0	17126232	intron_variant	0	NR	4e-07	6.39794000867204	(BMI)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	8p22	8	18120141	ASAH1	AC124242.3			ENSG00000286542	NA	NA	rs17126232-?	rs17126232	0	17126232	intron_variant	0	NR	2e-07	6.69897000433602	(HIP)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	2q31.3	2	180497652	UBE2E3	AC012669.1 - AC009478.1	ENSG00000270289	ENSG00000225258		24233	74060	rs16867321-?	rs16867321	0	16867321	intergenic_variant	1	NR	2e-06	5.69897000433602	(obesity)	NA		Illumina [~ 550000]	N
2011-05-28	21552555	Wang K	2011-04-28	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21552555	A genome-wide association study on obesity and obesity-related traits.	Obesity	520 European ancestry cases, 540 European ancestry controls	1,196 European ancestry individuals	13q21.32	13	66393490	PCDH9	PCDH9			ENSG00000184226	NA	NA	rs17081231-?	rs17081231	0	17081231	intron_variant	0	NR	7e-07	6.15490195998574	(weight)	NA		Illumina [~ 550000]	N
2008-09-12	18057069	Cronin S	2007-12-07	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/18057069	A genome-wide association study of sporadic ALS in a homogenous Irish population.	Amyotrophic lateral sclerosis	221 Genetically Homogenous Irish cases, 211 Genetically Homogenous Irish controls	737 European ancestry cases, 721 European ancestry controls	7q36.2	7	154513713	DPP6	DPP6			ENSG00000130226	NA	NA	rs10260404-?	rs10260404	0	10260404	intron_variant	0	0.37	3e-06	5.52287874528034		1.37	[1.20-1.56]	Illumina [497917]	N
2008-06-16	18198356	Hakonarson H	2008-01-15	Diabetes	www.ncbi.nlm.nih.gov/pubmed/18198356	A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study.	Type 1 diabetes	467 European ancestry trios, 561 European ancestry cases, 1,143 European ancestry controls	946 European ancestry cases and 1,098 European ancestry controls from 549 families, 364 European ancestry trios	12q13.2	12	56018703	CDK2, RAB5B, SUOX, IKZF4, ERBB3	IKZF4			ENSG00000123411	NA	NA	rs1701704-C	rs1701704	0	1701704	intron_variant	0	0.35	9e-10	9.04575749056067		1.25	[1.12-1.40]	Illumina [543071]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	11p15.1	11	17388025	KCNJ11	KCNJ11			ENSG00000187486	NA	NA	rs5219-T	rs5219	0	5219	stop_gained	0	0.46	7e-11	10.1549019599857	(DGI+FUSION+WTCCC)	1.14	[1.10-1.19]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	11p12	11	41893816	intergenic	AC023442.2 - LINC02745	ENSG00000254822	ENSG00000255300		16738	99565	rs9300039-C	rs9300039	0	9300039	intergenic_variant	1	0.89	6e-08	7.22184874961636		1.48	[1.28-1.71]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	3q27.2	3	185793899	IGF2BP2	IGF2BP2			ENSG00000073792	NA	NA	rs4402960-T	rs4402960	0	4402960	intron_variant	0	0.30	9e-16	15.0457574905607	(DGI+FUSION+WTCCC)	1.14	[1.11-1.18]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	16q12.2	16	53782363	FTO	FTO			ENSG00000140718	NA	NA	rs8050136-A	rs8050136	0	8050136	intron_variant	0	0.38	1e-12	12	(DGI+FUSION+WTCCC)	1.17	[1.12-1.22]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	3p25.2	3	12351626	PPARG	PPARG			ENSG00000132170	NA	NA	rs1801282-C	rs1801282	0	1801282	missense_variant	0	0.82	2e-06	5.69897000433602	(DGI+FUSION+WTCCC)	1.14	[1.08-1.20]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	10q23.33	10	92703125	HHEX	HHEX - Y_RNA	ENSG00000152804	ENSG00000265852		7478	7374	rs1111875-C	rs1111875	0	1111875	intergenic_variant	1	0.52	6e-10	9.22184874961636	(DGI+FUSION+WTCCC)	1.13	[1.09-1.17]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	9p21.3	9	22134095	CDKN2A, CDKN2B	CDKN2B-AS1 - AL157937.1	ENSG00000240498	ENSG00000236921		5992	69895	rs10811661-T	rs10811661	0	10811661	intergenic_variant	1	0.85	8e-15	14.0969100130081	(DGI+FUSION+WTCCC)	1.2	[1.14-1.25]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	6p22.3	6	20661019	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs7754840-C	rs7754840	0	7754840	intron_variant	0	0.36	4e-11	10.397940008672	(DGI+FUSION+WTCCC)	1.12	[1.08-1.16]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	0	0.18	1e-08	8		1.34	[1.21-1.49]	Illumina [315635]	N
2008-06-16	17463248	Scott LJ	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463248	A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants.	Type 2 diabetes	1,161 European ancestry cases, 1,174 European ancestry controls	1,215 European ancestry cases, 1,258 European ancestry controls	8q24.11	8	117172544	SLC30A8	SLC30A8			ENSG00000164756	NA	NA	rs13266634-C	rs13266634	0	13266634	missense_variant	0	0.61	5e-08	7.30102999566398	(DGI+FUSION+WTCCC)	1.12	[1.07-1.16]	Illumina [315635]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	6p24.1	6	12196980	intergenic	HIVEP1 - EDN1	ENSG00000095951	ENSG00000078401		31981	93381	rs1040994-?	rs1040994	0	1040994	intergenic_variant	1	NR	2e-06	5.69897000433602	(olanzapine)	9	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	9q33.3	9	126166744	intergenic	AL589923.1 - AL162391.1	ENSG00000232413	ENSG00000228392		7131	103377	rs888219-?	rs888219	0	888219	intergenic_variant	1	NR	2e-07	6.69897000433602	(risperidone)	11	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	1q21.3	1	152565478	intergenic	CRCT1 - LCE3E	ENSG00000169509	ENSG00000185966		49470	176	rs10888501-?	rs10888501	0	10888501	intergenic_variant	1	NR	1e-06	6	(olanzapine)	9	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	4p15.1	4	34892233	intergenic	AC093913.1 - AC020589.1	ENSG00000275250	ENSG00000238694		177635	74008	rs17390445-?	rs17390445	0	17390445	intergenic_variant	1	NR	1e-07	7	(ziprasidone)	17	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	3q28	3	191949988	intergenic	Y_RNA - AC026320.2	ENSG00000265852	ENSG00000237653		308751	2361	rs7635839-?	rs7635839	0	7635839	intergenic_variant	1	NR	3e-06	5.52287874528034	(olanzapine)	9	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	2q14.3	2	124524333	CNTNAP5	CNTNAP5			ENSG00000155052	NA	NA	rs17727261-?	rs17727261	0	17727261	missense_variant	0	NR	5e-07	6.30102999566398	(risperidone)	10	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	15q13.3	15	31042159	TRPM1	TRPM1, AC009562.1			ENSG00000274965, ENSG00000259720	NA	NA	rs17815774-?	rs17815774	0	17815774	missense_variant	0	NR	3e-06	5.52287874528034	(risperidone)	9	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	6p21.33	6	30768374	intergenic	HCG20, HCG20, HCG20, HCG20, HCG20, HCG20			ENSG00000224133, ENSG00000238216, ENSG00000224641, ENSG00000228022, ENSG00000224923, ENSG00000228762	NA	NA	rs12526186-?	rs12526186	0	12526186	intron_variant	0	NR	3e-06	5.52287874528034	(risperidone)	9	[NR] % variance	Affymetrix, Perlegen [492900]	N
2009-09-28	19721433	McClay JL	2009-09-01	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/19721433	Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics.	Response to antipsychotic treatment	494 European ancestry cases, 244 African American and other ancestry cases	NA	12q23.1	12	99423064	ANKS1B	ANKS1B			ENSG00000185046	NA	NA	rs7968606-?	rs7968606	0	7968606	intron_variant	0	NR	3e-07	6.52287874528034	(olanzapine)	10	[NR] % variance	Affymetrix, Perlegen [492900]	N
2008-09-12	18776911	Hazra A	2008-09-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18776911	Common variants of FUT2 are associated with plasma vitamin B12 levels.	Vitamin B12 levels	1,658 European ancestry female individuals	1,059 European ancestry female individuals	19q13.33	19	48703160	FUT2	FUT2			ENSG00000176920	NA	NA	rs492602-A	rs492602	0	492602	synonymous_variant	0	0.51	5e-17	16.301029995664		0.09	[0.070-0.110] unit decrease	Illumina [528134]	N
2009-01-07	19030899	Lei SF	2008-11-23	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19030899	Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.	Height	618 Chinese ancestry individuals	2,953 Chinese ancestry individuals	9q22.33	9	96776856	ZNP510	ZNF510			ENSG00000081386	NA	NA	rs10816533-C	rs10816533	0	10816533	intron_variant	0	0.29	2e-06	5.69897000433602		NA		Affymetrix [281533]	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	3p14.3	3	56831748	ARHGEF3	ARHGEF3			ENSG00000163947	NA	NA	rs12485738-A	rs12485738	0	12485738	intron_variant	0	NR	6e-31	30.2218487496164		0.02	[0.013-0.017] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	10q21.3	10	63373396	JMJD1C	JMJD1C			ENSG00000171988	NA	NA	rs2393967-A	rs2393967	0	2393967	intron_variant	0	NR	3e-21	20.5228787452803		0.01	[0.01-0.018] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	18q22.2	18	69849610	CD226	CD226			ENSG00000150637	NA	NA	rs893001-C	rs893001	0	893001	intron_variant	0	NR	1e-10	10		0.01	[0.007-0.015] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	20p12.1	20	14407569	NR	MACROD2			ENSG00000172264	NA	NA	rs6110278-T	rs6110278	0	6110278	intron_variant	0	NR	4e-07	6.39794000867204		0.01	[0.005-0.013] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	1q24.3	1	171980610	DNM3	DNM3			ENSG00000197959	NA	NA	rs10914144-C	rs10914144	0	10914144	intron_variant	0	NR	2e-14	13.698970004336		0.01	[0.009-0.017] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	11p15.5	11	202856	BET1L	BET1L			ENSG00000177951	NA	NA	rs11602954-G	rs11602954	0	11602954	intron_variant	0	NR	1e-14	14		0.01	[0.009-0.017] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	1q32.1	1	205266862	TMCC2	TMCC2			ENSG00000133069	NA	NA	rs1668873-G	rs1668873	0	1668873	intron_variant	0	NR	1e-20	20		0.01	[0.01-0.014] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	12q24.31	12	121927677	WDR66	WDR66			ENSG00000158023	NA	NA	rs7961894-T	rs7961894	0	7961894	intron_variant	0	NR	3e-44	43.5228787452803		0.03	[0.027-0.035] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	17q11.2	17	29376331	TAOK1	AC068025.1, AC068025.2			ENSG00000264808, ENSG00000266111	NA	NA	rs2138852-T	rs2138852	0	2138852	intron_variant	0	NR	1e-22	22		0.02	[0.012-0.020] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	7q22.3	7	106731773	PIK3CG	AC004917.1			ENSG00000243797	NA	NA	rs342293-G	rs342293	0	342293	intron_variant	0	NR	2e-33	32.698970004336		0.02	[0.013-0.017] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	2p23.1	2	31241963	EHD3	EHD3			ENSG00000013016	NA	NA	rs647316-A	rs647316	0	647316	intron_variant	0	NR	3e-11	10.5228787452803		0.01	[0.006-0.014] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	5q33.3	5	159176563	NR	RNF145			ENSG00000145860	NA	NA	rs1473247-C	rs1473247	0	1473247	intron_variant	0	NR	3e-07	6.52287874528034		0.01	[0.004-0.012] fl decrease	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	12q13.13	12	54293448	NR	NFE2, AC078778.1			ENSG00000123405, ENSG00000258344	NA	NA	rs10506328-A	rs10506328	0	10506328	intron_variant	0	NR	5e-07	6.30102999566398		0.01	[0.004-0.012] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	20p13	20	1943088	SIRPA	SIRPA - PDYN-AS1	ENSG00000198053	ENSG00000233896		2496	4158	rs6136489-T	rs6136489	0	6136489	intergenic_variant	1	NR	8e-11	10.0969100130081		0.01	[0.006-0.014] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Mean platelet volume	4,627 European ancestry individuals	9,316 European ancestry individuals	15q22.2	15	63049797	TPM1	TPM1			ENSG00000140416	NA	NA	rs11071720-T	rs11071720	0	11071720	intron_variant	0	NR	2e-08	7.69897000433602		0.01	[0.007-0.015] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	7q22.1	7	100638347	TFR2	TFR2			ENSG00000106327	NA	NA	rs7385804-C	rs7385804	0	7385804	intron_variant	0	NR	5e-10	9.30102999566398	(RBC)	0.01	[0.004-0.008] 10^12/l increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	9p24.1	9	4763176	AK3	AL353151.2 - ECM1P1	ENSG00000287759	ENSG00000270639		3537	5441	rs385893-C	rs385893	0	385893	regulatory_region_variant	1	NR	9e-17	16.0457574905607	(PLT)	6.26	[4.78-7.74] 10^9/l increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	NR	1e-23	23	(MCV)	1.41	[1.13-1.69] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	6p21.32	6	32445682	intergenic	HLA-DRA - HLA-DRB9	ENSG00000234794	ENSG00000226035		636	14139	rs2227139-G	rs2227139	0	2227139	intergenic_variant	1	NR	1e-07	7	(WBC)	0.02	[0.01-0.03] 10^9/l increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	22q12.3	22	37071352	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs5756506-C	rs5756506	0	5756506	intron_variant	0	NR	1e-09	9	(MCH)	0.14	[0.10-0.18] pg increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	6p21.1	6	41957552	BYSL, CCND3	CCND3			ENSG00000112576	NA	NA	rs11970772-T	rs11970772	0	11970772	intron_variant	0	NR	7e-19	18.1549019599857	(MCV)	0.58	[0.44-0.70] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	22q12.3	22	32471541	FBX07	BPIFC - FBXO7	ENSG00000184459	ENSG00000100225		7057	3135	rs9609565-G	rs9609565	0	9609565	intergenic_variant	1	NR	4e-10	9.39794000867204	(MCV)	0.37	[0.25-0.49] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	6q23.3	6	135106679	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		3623	74629	rs9402686-A	rs9402686	0	9402686	intergenic_variant	1	NR	7e-42	41.1549019599857	(MCV)	0.82	[0.70-0.94] fl increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	6q21	6	109768846	intergenic	FIG4			ENSG00000112367	NA	NA	rs4947019-G	rs4947019	0	4947019	intron_variant	0	NR	8e-06	5.09691001300806	(MCV)	0.01	[0.003-0.011] fl decrease	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	17q21.1	17	39954436	GSDMA, ORMDL3	GSDMA			ENSG00000167914	NA	NA	rs17609240-G	rs17609240	0	17609240	intron_variant	0	NR	9e-09	8.04575749056067	(WBC)	0.02	[0.01-0.03] 10^9/l increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2011-01-06	21084426	Saad M	2010-11-17	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21084426	Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.	Parkinson's disease	1,039 European ancestry cases, 1,984 European ancestry controls	3,232 European ancestry cases, 7,064 European ancestry controls	4q22.1	4	89720189	SNCA	AC093866.1			ENSG00000251095	NA	NA	rs356220-T	rs356220	0	356220	intron_variant	0	0.35	3e-08	7.52287874528034		1.37	[NR]	Illumina [492929]	N
2011-01-06	21084426	Saad M	2010-11-17	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21084426	Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.	Parkinson's disease	1,039 European ancestry cases, 1,984 European ancestry controls	3,232 European ancestry cases, 7,064 European ancestry controls	4p15.32	4	15735725	BST1	BST1			ENSG00000109743	NA	NA	rs4698412-A	rs4698412	0	4698412	intron_variant	0	0.55	2e-06	5.69897000433602		1.14	[1.08-1.20]	Illumina [492929]	N
2011-01-06	21084426	Saad M	2010-11-17	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21084426	Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population.	Parkinson's disease	1,039 European ancestry cases, 1,984 European ancestry controls	3,232 European ancestry cases, 7,064 European ancestry controls	12q23.3	12	106556209	intergenic	AC079385.1			ENSG00000257545	NA	NA	rs4964469-A	rs4964469	0	4964469	intron_variant	0	0.37	2e-07	6.69897000433602		1.16	[1.09-1.22]	Illumina [492929]	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	6p21.31	6	33572915	BAK1	GGNBP1, BAK1			ENSG00000204188, ENSG00000030110	NA	NA	rs210135-A	rs210135	0	210135	3_prime_UTR_variant	0	NR	4e-10	9.39794000867204	(PLT)	5.44	[3.74-7.14] 10^9/l increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2009-10-30	19820697	Soranzo N	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19820697	A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.	Hematological parameters	4,627 European ancestry individuals	9,316 European ancestry individuals	12q24.13	12	112433568	PTPN11	PTPN11			ENSG00000179295	NA	NA	rs11066301-G	rs11066301	0	11066301	intron_variant	0	NR	8e-12	11.0969100130081	(PLT)	4.65	[3.32-5.98] 10^9/l increase	Affymetrix, Illumina [~ 2110000] (imputed)	N
2012-08-07	22683750	Sinner MF	2012-06-06	Heart Rhythm	www.ncbi.nlm.nih.gov/pubmed/22683750	A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.	Early cardiac repolarization	7,482 European ancestry individuals	7,151 European ancestry individuals	17q25.2	17	77008131	MGAT5B, SEC14L	AC016168.3 - Metazoa_SRP	ENSG00000280122	ENSG00000278569		38601	6749	rs11653989-T	rs11653989	0	11653989	intergenic_variant	1	0.917	3e-06	5.52287874528034		1.61	[1.32-2.0]	Affymetrix, Illumina [2523555] (imputed)	N
2012-08-07	22683750	Sinner MF	2012-06-06	Heart Rhythm	www.ncbi.nlm.nih.gov/pubmed/22683750	A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.	Early cardiac repolarization	7,482 European ancestry individuals	7,151 European ancestry individuals	10q26.11	10	117450864	PDZD8, EMX2	AC005871.2			ENSG00000258114	NA	NA	rs6585436-C	rs6585436	0	6585436	intron_variant	0	0.983	6e-06	5.22184874961636		2.08	[1.52-2.86]	Affymetrix, Illumina [2523555] (imputed)	N
2012-08-07	22683750	Sinner MF	2012-06-06	Heart Rhythm	www.ncbi.nlm.nih.gov/pubmed/22683750	A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern.	Early cardiac repolarization	7,482 European ancestry individuals	7,151 European ancestry individuals	1p13.2	1	111921754	KCND3	KCND3			ENSG00000171385	NA	NA	rs17029069-T	rs17029069	0	17029069	intron_variant	0	0.356	8e-06	5.09691001300806		1.29	[1.15-1.44]	Affymetrix, Illumina [2523555] (imputed)	N
2009-02-27	19116933	Hinks A	2009-01-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/19116933	Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.	Arthritis (juvenile idiopathic)	279 European ancestry cases, 184 European ancestry controls	up to 654 European ancestry cases, 2,024 European ancestry controls	1p12	1	117208743	VTCN1	VTCN1			ENSG00000134258	NA	NA	rs12046117-?	rs12046117	0	12046117	intron_variant	0	0.09	1e-06	6		1.58	[1.29-1.94]	Affymetrix [88862]	N
2010-01-21	20060832	Rauch A	2010-01-07	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/20060832	Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.	Chronic hepatitis C infection	1,015 European ancestry chronic HCV carriers, 347 European ancestry spontaneously cleared HCV individuals	NA	19q13.2	19	39252525	IL29, IL28B, IL28A	IFNL4 - MSRB1P1	ENSG00000272395	ENSG00000213926		3669	2391	rs8099917-G	rs8099917	0	8099917	intergenic_variant	1	0.24	6e-09	8.22184874961636		2.31	[1.74-3.06]	Illumina [~ 500000]	N
2009-09-30	19749758	Suppiah V	2009-09-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19749758	IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy.	Response to hepatitis C treatment	131 European ancestry responders, 162 European ancestry non-responders	261 European ancestry responders, 294 European ancestry non-responders	19q13.2	19	39252525	IL28A, IL28B	IFNL4 - MSRB1P1	ENSG00000272395	ENSG00000213926		3669	2391	rs8099917-G	rs8099917	0	8099917	intergenic_variant	1	NR	9e-09	8.04575749056067		1.98	[1.57-2.52]	Illumina [311159]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	12p13.1	12	13774962	GRIN2B	GRIN2B			ENSG00000273079	NA	NA	rs6488619-?	rs6488619	0	6488619	intron_variant	0		9e-07	6.04575749056067	(FSH levels - EA)	NA		Affymetrix [677261]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	5p13.3	5	32748531	NPR3	NPR3			ENSG00000113389	NA	NA	rs10061804-?	rs10061804	0	10061804	intron_variant	0		1e-06	6	(FSH levels - EA)	NA		Affymetrix [677261]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	3p25.1	3	13919660	TPRXL	WNT7A - VN1R20P	ENSG00000154764	ENSG00000233121		39589	7153	rs9875589-?	rs9875589	0	9875589	intergenic_variant	1		4e-06	5.39794000867204	(AMH levels - AA)	NA		Affymetrix [677261]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	11p15.1	11	18668106	TMEM86A	AP006296.1 - TMEM86A	ENSG00000257043	ENSG00000151117		2558	25016	rs12295403-?	rs12295403	0	12295403	regulatory_region_variant	1		5e-06	5.30102999566398	(AMH levels- AA)	NA		Affymetrix [677261]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	6p23	6	14586772	JARID2	AL009177.1 - AL109914.1	ENSG00000286277	ENSG00000229646		84071	10742	rs12213875-?	rs12213875	0	12213875	intergenic_variant	1		3e-07	6.52287874528034	(AMH - EA)	NA		Affymetrix [677261]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	2p22.3	2	34405965	MYADML	LINC01320			ENSG00000228262	NA	NA	rs6543833-?	rs6543833	0	6543833	intron_variant	0		8e-08	7.09691001300806	(FSH levels - AA)	NA		Affymetrix [677261]	N
2012-01-11	22116950	Schuh-Huerta SM	2011-11-24	Hum Reprod	www.ncbi.nlm.nih.gov/pubmed/22116950	Genetic variants and environmental factors associated with hormonal markers of ovarian reserve in Caucasian and African American women.	Ovarian reserve	232 European ancestry female individuals, 200 African American female individuals	NA	10p14	10	7694941	ITIH2	ITIH5 - ITIH2	ENSG00000123243	ENSG00000151655		27943	8375	rs11255291-?	rs11255291	0	11255291	intergenic_variant	1		2e-06	5.69897000433602	(FSH levels - AA)	NA		Affymetrix [677261]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	8q24.11	8	117172544	SLC30A8	SLC30A8			ENSG00000164756	NA	NA	rs13266634-C	rs13266634	0	13266634	missense_variant	0	0.65	5e-08	7.30102999566398		1.12	[1.07-1.16]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	9p21.3	9	22134095	CDKN2A, CDKN2B	CDKN2B-AS1 - AL157937.1	ENSG00000240498	ENSG00000236921		5992	69895	rs10811661-T	rs10811661	0	10811661	intergenic_variant	1	0.83	8e-15	14.0969100130081		1.2	[1.14-1.25]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	11p15.1	11	17388025	KCNJ11	KCNJ11			ENSG00000187486	NA	NA	rs5219-T	rs5219	0	5219	stop_gained	0	0.47	7e-11	10.1549019599857		1.14	[1.10-1.19]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	10q23.33	10	92703125	HHEX	HHEX - Y_RNA	ENSG00000152804	ENSG00000265852		7478	7374	rs1111875-C	rs1111875	0	1111875	intergenic_variant	1	0.53	6e-10	9.22184874961636		1.13	[1.08-1.17]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	3p25.2	3	12351626	PPARG	PPARG			ENSG00000132170	NA	NA	rs1801282-C	rs1801282	0	1801282	missense_variant	0	0.86	2e-06	5.69897000433602		1.14	[1.08-1.20]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	6p22.3	6	20661019	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs7754840-C	rs7754840	0	7754840	intron_variant	0	0.31	4e-11	10.397940008672		1.12	[1.08-1.16]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	3q27.2	3	185793899	IGF2BP2	IGF2BP2			ENSG00000073792	NA	NA	rs4402960-T	rs4402960	0	4402960	intron_variant	0	0.29	9e-16	15.0457574905607		1.14	[1.11-1.18]	Affymetrix [386731]	N
2008-06-16	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Type 2 diabetes	1,464 European ancestry cases, 1,467 European ancestry controls	5,065 European ancestry cases, 5,785 European ancestry controls, at least 18,129 cases and controls.	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	0	0.26	1e-48	48		1.37	[1.31-1.43]	Affymetrix [386731]	N
2009-02-13	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Triglycerides	2,659 European ancestry type 2 diabetes cases and controls	5,217 European ancestry individuals	8p21.3	8	19975135	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		7876	103979	rs17482753-T	rs17482753	0	17482753	regulatory_region_variant	1	0.1	5e-07	6.30102999566398		1	(% variance) increase	Affymetrix [389878]	N
2009-02-13	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Triglycerides	2,659 European ancestry type 2 diabetes cases and controls	5,217 European ancestry individuals	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-T	rs780094	0	780094	intron_variant	0	0.35	9e-08	7.04575749056067		0.5	(% variance) increase	Affymetrix [389878]	N
2017-11-01	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	HDL cholesterol levels	2,623 European ancestry type 2 diabetes cases and controls	NA	16q13	16	56961324	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		16460	599	rs1800775-C	rs1800775	0	1800775	regulatory_region_variant	1	0.47	3e-13	12.5228787452803		2.1	(% variance) increase	Affymetrix [389878]	N
2017-11-01	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	LDL cholesterol levels	2,601 European ancestry type 2 diabetes cases and controls	NA	2p24.1	2	21009323	APOB	APOB			ENSG00000084674	NA	NA	rs693-A	rs693	0	693	synonymous_variant	0	0.49	7e-07	6.15490195998574		1	(% variance) increase	Affymetrix [389878]	N
2017-11-01	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	LDL cholesterol levels	2,601 European ancestry type 2 diabetes cases and controls	NA	19q13.32	19	44919689	APOE	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-G	rs4420638	0	4420638	regulatory_region_variant	1	0.22	3e-13	12.5228787452803		2.1	(% variance) increase	Affymetrix [389878]	N
2017-11-01	17463246	Saxena R	2007-04-26	Science	www.ncbi.nlm.nih.gov/pubmed/17463246	Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.	Apolipoprotein A1 levels	1,451 European ancestry type 2 diabetes cases and controls	NA	16q13	16	56961324	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		16460	599	rs1800775-C	rs1800775	0	1800775	regulatory_region_variant	1	0.44	3e-06	5.52287874528034		1.6	(% variance) increase	Affymetrix [389878]	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	2p23.3	2	27684606	SLC4A1AP	SLC4A1AP			ENSG00000163798	NA	NA	rs17006206-G	rs17006206	0	17006206	intron_variant	0	0.10	2e-06	5.69897000433602		2.05	[1.52-2.76]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	8q24.13	8	121897448	intergenic	HAS2-AS1			ENSG00000248690	NA	NA	rs956225-A	rs956225	0	956225	intron_variant	0	NR	9e-06	5.04575749056067		3.33	[1.96-5.56]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	1q32.3	1	213944747	intergenic	PROX1-AS1			ENSG00000230461	NA	NA	rs340849-?	rs340849	0	340849	intron_variant	0	NR	8e-06	5.09691001300806		1.69	[1.33-2.13]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	2p24.2	2	17246318	intergenic	RN7SKP168 - ZFYVE9P2	ENSG00000222842	ENSG00000214843		123178	37974	rs11889338-A	rs11889338	0	11889338	regulatory_region_variant	1	0.26	9e-06	5.04575749056067		1.55	[1.28-1.88]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	3p24.1	3	28887369	intergenic	AC098650.1, RBMS3			ENSG00000283563, ENSG00000144642	NA	NA	rs2221154-?	rs2221154	0	2221154	intron_variant	0	NR	3e-06	5.52287874528034		1.75	[1.39-2.22]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	4p16.3	4	2101369	POLN	HAUS3, POLN			ENSG00000214367, ENSG00000130997	NA	NA	rs1923775-T	rs1923775	0	1923775	intron_variant	0	0.25	6e-06	5.22184874961636		1.6	[1.30-1.95]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	7q35	7	147200311	CNTNAP2	CNTNAP2			ENSG00000174469	NA	NA	rs10273775-G	rs10273775	0	10273775	intron_variant	0	0.42	9e-06	5.04575749056067		1.52	[1.27-1.84]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	12q24.21	12	114942588	intergenic	AC009804.1 - AC008125.1	ENSG00000274879	ENSG00000257958		12653	134737	rs10850408-?	rs10850408	0	10850408	intergenic_variant	1	NR	9e-07	6.04575749056067		1.59	[1.32-1.92]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	13q32.2	13	98479040	STK24	STK24			ENSG00000102572	NA	NA	rs912330-?	rs912330	0	912330	intron_variant	0	NR	4e-06	5.39794000867204		1.85	[1.43-2.44]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	19q13.32	19	44878777	PVRL2	NECTIN2			ENSG00000130202	NA	NA	rs6859-A	rs6859	0	6859	3_prime_UTR_variant	0	NR	5e-07	6.30102999566398		1.58	[NR]	Illumina [2505093] (imputed)	N
2012-01-06	22159054	Logue MW	2011-12-01	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/22159054	A comprehensive genetic association study of Alzheimer disease in African Americans.	Alzheimer's disease	513 African American cases, 496 African American controls	NA	13q12.13	13	26150190	intergenic	ATP8A2P3, RNF6			ENSG00000233963, ENSG00000127870	NA	NA	rs17511627-C	rs17511627	0	17511627	intron_variant	0	0.17	5e-06	5.30102999566398		1.75	[1.37-2.22]	Illumina [2505093] (imputed)	N
2010-10-05	20835238	Thorleifsson G	2010-09-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20835238	Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.	Glaucoma (primary open-angle)	1,263 European ancestry cases, 34,887 European ancestry controls	2,175 European ancestry cases, 2,064 European ancestry controls	7q31.2	7	116522675	CAV1, CAV2	CAV2 - CAV1	ENSG00000105971	ENSG00000105974		14134	2326	rs4236601-A	rs4236601	0	4236601	regulatory_region_variant	1	0.23	2e-11	10.698970004336		1.27	[1.18-1.36]	Illumina [303117]	N
2009-09-28	19727025	De Moor MH	2009-09-02	Med Sci Sports Exerc	www.ncbi.nlm.nih.gov/pubmed/19727025	Genome-wide association study of exercise behavior in Dutch and American adults.	Leisure-time exercise behaviour	2,622 European ancestry individuals	NA	2q33.1	2	200293399	DNAPTP6	AC004464.1 - SPATS2L	ENSG00000287027	ENSG00000196141		193374	12482	rs12612420-A	rs12612420	0	12612420	intergenic_variant	1	NR	8e-06	5.09691001300806		1.43	[1.22-1.67]	Affymetrix, Perlegen [~ 1600000] (imputed)	N
2009-09-28	19727025	De Moor MH	2009-09-02	Med Sci Sports Exerc	www.ncbi.nlm.nih.gov/pubmed/19727025	Genome-wide association study of exercise behavior in Dutch and American adults.	Leisure-time exercise behaviour	2,622 European ancestry individuals	NA	10q23.2	10	87683553	PAPSS2	PAPSS2			ENSG00000198682	NA	NA	rs10887741-T	rs10887741	0	10887741	intron_variant	0	NR	4e-06	5.39794000867204		1.32	[1.17-1.49]	Affymetrix, Perlegen [~ 1600000] (imputed)	N
2009-09-28	19727025	De Moor MH	2009-09-02	Med Sci Sports Exerc	www.ncbi.nlm.nih.gov/pubmed/19727025	Genome-wide association study of exercise behavior in Dutch and American adults.	Leisure-time exercise behaviour	2,622 European ancestry individuals	NA	18p11.32	18	1595020	C18orf2	AP005262.2			ENSG00000266602	NA	NA	rs8097348-G	rs8097348	0	8097348	intron_variant	0	NR	7e-06	5.15490195998574		1.36	[1.19-1.56]	Affymetrix, Perlegen [~ 1600000] (imputed)	N
2009-09-29	19734900	Rung J	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734900	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	Type 2 diabetes	679 European ancestry cases, 697 European ancestry controls	5,579 European ancestry cases, 7,096 European ancestry controls	2q36.3	2	226229029	LOC64673, IRS1	AC062015.1 - MIR5702	ENSG00000235070	ENSG00000263363		43658	429681	rs2943641-C	rs2943641	0	2943641	intergenic_variant	1	0.63	9e-12	11.0457574905607		1.19	[1.13-1.25]	Illumina [392365]	N
2009-09-29	19734900	Rung J	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734900	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	Type 2 diabetes	679 European ancestry cases, 697 European ancestry controls	5,579 European ancestry cases, 7,096 European ancestry controls	4p16.1	4	6268329	PPP2R2C, WFS1	LINC02495 - WFS1	ENSG00000249896	ENSG00000109501		28392	1520	rs4689388-T	rs4689388	0	4689388	intergenic_variant	1	0.57	1e-08	8		1.16	[1.10-1.21]	Illumina [392365]	N
2009-09-29	19734900	Rung J	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734900	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	Type 2 diabetes	679 European ancestry cases, 697 European ancestry controls	5,579 European ancestry cases, 7,096 European ancestry controls	5q14.3	5	90250292	LOC72901, CETN3	LINC01339			ENSG00000248555	NA	NA	rs12518099-C	rs12518099	0	12518099	intron_variant	0	0.23	7e-07	6.15490195998574		1.16	[1.10-1.22]	Illumina [392365]	N
2009-09-29	19734900	Rung J	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734900	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	Type 2 diabetes	679 European ancestry cases, 697 European ancestry controls	5,579 European ancestry cases, 7,096 European ancestry controls	6p22.3	6	20657333	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs4712523-G	rs4712523	0	4712523	intron_variant	0	0.32	2e-12	11.698970004336		1.2	[1.14-1.26]	Illumina [392365]	N
2009-09-29	19734900	Rung J	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734900	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	Type 2 diabetes	679 European ancestry cases, 697 European ancestry controls	5,579 European ancestry cases, 7,096 European ancestry controls	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	0	0.27	1e-30	30		1.48	[1.39-1.57]	Illumina [392365]	N
2009-09-29	19734900	Rung J	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734900	Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia.	Type 2 diabetes	679 European ancestry cases, 697 European ancestry controls	5,579 European ancestry cases, 7,096 European ancestry controls	8q24.11	8	117172544	SLC30A8	SLC30A8			ENSG00000164756	NA	NA	rs13266634-C	rs13266634	0	13266634	missense_variant	0	0.68	8e-08	7.09691001300806		1.16	[1.10-1.22]	Illumina [392365]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	8q24.21	8	127527115	intergenic	CASC8 - AC104370.1	ENSG00000246228	ENSG00000286266		44976	51358	rs7837688-?	rs7837688	0	7837688	intergenic_variant	1	NR	1e-25	25		NA		Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	8q24.21	8	127091692	intergenic	PRNCR1, PCAT1, CASC19			ENSG00000282961, ENSG00000253438, ENSG00000254166	NA	NA	rs1456315-?	rs1456315	0	1456315	non_coding_transcript_exon_variant	0	NR	2e-29	28.698970004336		NA		Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	2p24.1	2	20688505	C2orf43	LDAH			ENSG00000118961	NA	NA	rs13385191-G	rs13385191	0	13385191	intron_variant	0	0.44	8e-08	7.09691001300806		1.15	[1.10-1.21]	Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	6q22.1	6	116888889	GPRC6A, RFX6	RFX6			ENSG00000185002	NA	NA	rs339331-T	rs339331	0	339331	intron_variant	0	0.37	2e-12	11.698970004336		1.22	[1.15-1.28]	Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	13q22.1	13	73154002	intergenic	RNU6-66P - RNU4-10P	ENSG00000200267	ENSG00000201253		40984	37526	rs9600079-T	rs9600079	0	9600079	intergenic_variant	1	0.38	3e-09	8.52287874528034		1.18	[1.12-1.24]	Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	3p11.2	3	87103019	intergenic	AC107204.1			ENSG00000281392	NA	NA	rs9284813-?	rs9284813	0	9284813	intron_variant	0	NR	5e-09	8.30102999566398		NA		Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	8p21.2	8	23668950	NKX3.1	SINHCAFP3 - NKX3-1	ENSG00000253488	ENSG00000167034		33443	9747	rs1512268-?	rs1512268	0	1512268	intergenic_variant	1	NR	4e-11	10.397940008672		NA		Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	10q11.22	10	46046326	MSMB	MSMB			ENSG00000263639	NA	NA	rs10993994-?	rs10993994	0	10993994	5_prime_UTR_variant	0	NR	3e-08	7.52287874528034		NA		Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	17q12	17	37741165	HNF1B	HNF1B, HNF1B			ENSG00000276194, ENSG00000275410	NA	NA	rs7501939-?	rs7501939	0	7501939	intron_variant	0	NR	1e-12	12		NA		Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	5p15.33	5	1895715	intergenic	AC025183.2			ENSG00000249326	NA	NA	rs12653946-T	rs12653946	0	12653946	intron_variant	0	0.44	4e-18	17.397940008672		1.26	[1.20-1.33]	Illumina [510687]	N
2010-09-11	20676098	Takata R	2010-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20676098	Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.	Prostate cancer	1,583 Japanese ancestry cases, 3,386 Japanese ancestry controls	3,001 Japanese ancestry cases, 5,415 Japanese ancestry controls	6p21.1	6	41568689	FOXP4	FOXP4			ENSG00000137166	NA	NA	rs1983891-T	rs1983891	0	1983891	intron_variant	0	0.41	8e-08	7.09691001300806		1.15	[1.09-1.21]	Illumina [510687]	N
2010-09-17	20802479	Anttila V	2010-08-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20802479	Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.	Migraine	2,731 European ancestry cases, 10,747 European ancestry controls	3,202 European ancestry cases, 40,062 European ancestry controls	8q22.1	8	97154685	MTDH, PGCP	CPQ - AP003115.1	ENSG00000104324	ENSG00000260640		5031	87057	rs1835740-A	rs1835740	0	1835740	intergenic_variant	1	0.21	2e-11	10.698970004336		1.18	[1.13-1.24]	Illumina [429912]	N
2011-01-08	21113153	van der Zanden LF	2010-11-28	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21113153	Common variants in DGKK are strongly associated with risk of hypospadias.	Hypospadias	436 European ancestry cases, 494 European ancestry controls	133 European ancestry cases and their parents, 266 European ancestry cases, 402 European ancestry controls	Xp11.22	X	50439186	DGKK	DGKK			ENSG00000274588	NA	NA	rs1934179-A	rs1934179	0	1934179	intron_variant	0	0.33	3e-21	20.5228787452803		2.6	[2.1-3.1]	Affymetrix [574400]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	12p13.1	12	13634912	GRIN2B	GRIN2B			ENSG00000273079	NA	NA	rs2160519-?	rs2160519	0	2160519	intron_variant	0	0.05946	2e-06	5.69897000433602	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	17q21.32	17	48643203	AC103702.3	AC103702.2			ENSG00000272763	NA	NA	rs2326017-?	rs2326017	0	2326017	intron_variant	0	0.2985	3e-07	6.52287874528034	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	9p22.2	9	17899608	NR	SH3GL2 - ADAMTSL1	ENSG00000107295	ENSG00000178031		102484	6955	rs4284125-?	rs4284125	1	1977882	intergenic_variant	1	0.1267	8e-06	5.09691001300806	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	2p16.3	2	51440601	AC007402.3	AC007402.1			ENSG00000231918	NA	NA	rs1206397-?	rs1206397	0	1206397	intron_variant	0	0.0476	3e-07	6.52287874528034	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3q26.32	3	177879201	AC007953.21	LINC02015			ENSG00000231574	NA	NA	rs7612209-?	rs7612209	0	7612209	intron_variant	0	0.4012	4e-06	5.39794000867204	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	16q23.3	16	82346348	AC009117.8	RN7SKP190 - AC009117.1	ENSG00000251888	ENSG00000259873		153558	88480	rs4082514-?	rs4082514	0	4082514	intergenic_variant	1	0.02741	3e-06	5.52287874528034	(PC1)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	12p12.3	12	19648661	AC090059.9	AEBP2			ENSG00000139154	NA	NA	rs6486986-?	rs6486986	0	6486986	intron_variant	0	0.2253	8e-06	5.09691001300806	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	5p15.31	5	7227934	AC091951.3	AC091889.1			ENSG00000286254	NA	NA	rs7729273-?	rs7729273	0	7729273	intron_variant	0	0.1985	1e-06	6	(SSP)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	17q25.3	17	77215126	SEC14L1	SEC14L1			ENSG00000129657	NA	NA	rs3744064-?	rs3744064	0	3744064	3_prime_UTR_variant	0	0.03053	7e-07	6.15490195998574	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3q23	3	141260569	ACPL2	PXYLP1, AC022215.2			ENSG00000155893, ENSG00000287155	NA	NA	rs16851254-?	rs16851254	0	16851254	intron_variant	0	0.0313	8e-06	5.09691001300806	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	8q12.1	8	58795750	TOX	NSMAF - TOX	ENSG00000035681	ENSG00000198846		135897	9662	rs960089-?	rs960089	0	960089	intergenic_variant	1	0.06545	6e-06	5.22184874961636	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	13q21.33	13	72194571	AL445923.10	RPS10P21 - AL139003.1	ENSG00000232881	ENSG00000212377		280393	259331	rs4083578-?	rs4083578	0	4083578	intergenic_variant	1	0.2874	8e-06	5.09691001300806	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	11p12	11	43064544	API5	AC009643.2			ENSG00000271028	NA	NA	rs10501293-?	rs10501293	0	10501293	non_coding_transcript_exon_variant	0	0.2494	5e-06	5.30102999566398	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3p22.3	3	35940638	ARPP-21	AC104308.1 - RFC3P1	ENSG00000226489	ENSG00000236158		68440	229129	rs6799705-?	rs6799705	0	6799705	intergenic_variant	1	0.04563	2e-07	6.69897000433602	(PAL8)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	6p21.2	6	37519268	AL353597.20	LINC02520			ENSG00000204110	NA	NA	rs1757171-?	rs1757171	0	1757171	intron_variant	0	0.3884	7e-06	5.15490195998574	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	18q22.1	18	67349863	C18orf4, DSEL	RPL31P9 - AC091042.1	ENSG00000264054	ENSG00000265936		212112	25270	rs2124349-?	rs2124349	0	2124349	intergenic_variant	1	0.04926	4e-06	5.39794000867204	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	11q14.2	11	86344859	C11orf73	HIKESHI			ENSG00000149196	NA	NA	rs6592284-?	rs6592284	0	6592284	3_prime_UTR_variant	0	0.21	2e-06	5.69897000433602	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	6p21.2	6	37483920	C6orf129	CCDC167			ENSG00000198937	NA	NA	rs904251-?	rs904251	0	904251	intron_variant	0	0.3806	7e-06	5.15490195998574	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	11q13.5	11	77112438	CAPN5	CAPN5			ENSG00000149260	NA	NA	rs3781684-?	rs3781684	0	3781684	intron_variant	0	0.1135	7e-06	5.15490195998574	(VRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	15q23	15	68600650	CORO2B	CORO2B			ENSG00000103647	NA	NA	rs11856323-?	rs11856323	0	11856323	intron_variant	0	0.07883	1e-07	7	(PAL8)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	13q14.11	13	43153713	DNAJC15	DNAJC15 - LINC00400	ENSG00000120675	ENSG00000229928		39500	4918	rs1324015-?	rs1324015	0	1324015	regulatory_region_variant	1	0.4193	9e-06	5.04575749056067	(PC1)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	1p36.13	1	16066862	FAM131C	FAM131C			ENSG00000185519	NA	NA	rs9442235-?	rs9442235	0	9442235	intron_variant	0	0.4154	6e-06	5.22184874961636	(PC1)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	1q41	1	222750009	FAM177B	FAM177B, AL392172.2			ENSG00000197520, ENSG00000287684	NA	NA	rs6683071-?	rs6683071	0	6683071	missense_variant	0	0.2016	4e-06	5.39794000867204	(PC1)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	4q28.1	4	125505540	FAT4	FAT4 - MIR2054	ENSG00000196159	ENSG00000283550		12608	1719	rs12639834-?	rs12639834	0	12639834	intergenic_variant	1	0.358	6e-06	5.22184874961636	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	13q12.3	13	28355574	FLT1	FLT1			ENSG00000102755	NA	NA	rs17086609-?	rs17086609	0	17086609	intron_variant	0	0.3475	5e-06	5.30102999566398	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	2q31.1	2	170965956	GORASP2	GORASP2			ENSG00000115806	NA	NA	rs4668356-?	rs4668356	0	4668356	synonymous_variant	0	0.06041	1e-06	6	(PAL8)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	16p12.1	16	27045134	AC092725.3	AC009035.1 - C16orf82	ENSG00000260580	ENSG00000234186		316008	21573	rs2203512-?	rs2203512	0	2203512	intergenic_variant	1	0.1394	3e-07	6.52287874528034	(PRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	Xp22.2	X	11030572	HCCS	AC073529.1			ENSG00000234129	NA	NA	rs5934953-?	rs5934953	0	5934953	intron_variant	0	0.02285	1e-07	7	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	13q34	13	110817691	RP11-120J20.1	LINC00567 - LINC00346	ENSG00000259831	ENSG00000255874		4607	46296	rs767210-?	rs767210	0	767210	intergenic_variant	1	0.1089	3e-07	6.52287874528034	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	1p32.1	1	58859954	JUN	LINC01135			ENSG00000234807	NA	NA	rs4601609-?	rs4601609	0	4601609	intron_variant	0	0.04517	5e-06	5.30102999566398	(PRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	13q21.33	13	69881529	KLHL1	KLHL1			ENSG00000150361	NA	NA	rs7984606-?	rs7984606	0	7984606	intron_variant	0	0.01081	8e-06	5.09691001300806	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3p22.1	3	39512297	MOBP	MOBP			ENSG00000168314	NA	NA	rs816488-?	rs816488	0	816488	intron_variant	0	0.04479	4e-06	5.39794000867204	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	14q23.3	14	64432337	MTHFD1	MTHFD1, AL122035.1			ENSG00000100714, ENSG00000258824	NA	NA	rs10498514-?	rs10498514	0	10498514	intron_variant	0	0.01817	8e-07	6.09691001300806	(SWM strategy)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	21q11.2	21	14967968	NRIP1	AF127577.4, NRIP1			ENSG00000235609, ENSG00000180530	NA	NA	rs2229741-?	rs2229741	0	2229741	synonymous_variant	0	0.4726	6e-07	6.22184874961636	(SRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	20p12.3	20	8856124	PLCB1	PLCB1			ENSG00000182621	NA	NA	rs6056209-?	rs6056209	0	6056209	intron_variant	0	0.4347	2e-06	5.69897000433602	(RVP)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	Xq28	X	152487090	AC108171.5	KRT8P8 - AC244102.4	ENSG00000223940	ENSG00000287394		6066	87587	rs10856240-?	rs10856240	0	10856240	intergenic_variant	1	0.2913	9e-06	5.04575749056067	(PC1)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	9p22.2	9	17895107	SH3GL2	SH3GL2 - ADAMTSL1	ENSG00000107295	ENSG00000178031		97983	11456	rs10810865-?	rs10810865	0	10810865	intergenic_variant	1	0.127	4e-06	5.39794000867204	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	13q31.2	13	88110091	AL354896.16	TET1P1 - LINC00373	ENSG00000232204	ENSG00000231019		217619	32776	rs969962-?	rs969962	0	969962	intergenic_variant	1	0.1398	9e-06	5.04575749056067	(PAL8)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	19q12	19	31310224	TSHZ3	TSHZ3			ENSG00000121297	NA	NA	rs1078373-?	rs1078373	0	1078373	intron_variant	0	0.3707	6e-06	5.22184874961636	(SSP)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	1q23.2	1	160452126	VANGL2	VANGL2 - SLAMF6	ENSG00000162738	ENSG00000162739		23456	32904	rs16832015-?	rs16832015	0	16832015	regulatory_region_variant	1	0.01081	2e-06	5.69897000433602	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	Xp22.31	X	8426212	VCX3B	AC079142.1 - VCX3B	ENSG00000285679	ENSG00000205642		51826	38618	rs7892812-?	rs7892812	0	7892812	intergenic_variant	1	0.4747	8e-06	5.09691001300806	(SSP)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	12q23.3	12	107310928	BTBD11	SETP7 - BTBD11	ENSG00000257444	ENSG00000151136		39082	7493	rs1820460-?	rs1820460	0	1820460	intergenic_variant	1	0.2788	8e-06	5.09691001300806	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	12q24.23	12	120017960	CCDC64	BICDL1			ENSG00000135127	NA	NA	rs11064994-?	rs11064994	0	11064994	intron_variant	0	0.05521	6e-06	5.22184874961636	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	7p14.3	7	29001574	CPVL	AC005162.3, CPVL			ENSG00000272568, ENSG00000106066	NA	NA	rs2252521-?	rs2252521	0	2252521	intron_variant	0	0.3363	5e-06	5.30102999566398	(PAL8)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3q27.2	3	185228061	EHHADH	EHHADH			ENSG00000113790	NA	NA	rs7374394-?	rs7374394	0	7374394	intron_variant	0	0.2035	2e-06	5.69897000433602	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	8q24.13	8	123819594	FAM91A1	FAM91A1 - FER1L6	ENSG00000176853	ENSG00000214814		4142	32393	rs10481151-?	rs10481151	0	10481151	regulatory_region_variant	1	0.1414	4e-07	6.39794000867204	(PRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3q13.33	3	121625293	FBXO40	FBXO40			ENSG00000163833	NA	NA	rs3772130-?	rs3772130	0	3772130	intron_variant	0	0.2284	6e-06	5.22184874961636	(PC1)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	15q12	15	26727939	GABRB3	GABRB3			ENSG00000166206	NA	NA	rs8043440-?	rs8043440	0	8043440	intron_variant	0	0.1695	2e-06	5.69897000433602	(SRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	3p25.1	3	14489213	GRIP2	SLC6A6, GRIP2			ENSG00000131389, ENSG00000144596	NA	NA	rs9036-?	rs9036	0	9036	3_prime_UTR_variant	0	0.187	3e-06	5.52287874528034	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	7q31.1	7	110827165	IMMP2L	IMMP2L			ENSG00000184903	NA	NA	rs10279573-?	rs10279573	0	10279573	intron_variant	0	0.1446	3e-06	5.52287874528034	(IED)	NA		Illumina [475971]	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	20q13.12	20	45352086	SDC4	SDC4 - SYS1	ENSG00000124145	ENSG00000204070		3662	9851	rs1008953-C	rs1008953	0	1008953	intergenic_variant	1	0.79	1e-07	7		1.14	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	17p11.2	17	22180454	NR	UBBP4			ENSG00000263563	NA	NA	rs1975974-G	rs1975974	0	1975974	intron_variant	0	0.23	1e-07	7		1.17	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	2p16.1	2	60864815	NR	LINC01185			ENSG00000228414	NA	NA	rs842636-G	rs842636	0	842636	intron_variant	0	0.56	6e-06	5.22184874961636		1.15	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	16p11.2	16	30931304	FBXL19, POL3S	FBXL19			ENSG00000099364	NA	NA	rs10782001-G	rs10782001	0	10782001	intron_variant	0	0.37	9e-10	9.04575749056067		1.16	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	14q13.2	14	35212966	PSMA6, NFKBIA	AL121594.1, PRORP			ENSG00000258790, ENSG00000100890	NA	NA	rs12586317-T	rs12586317	0	12586317	intron_variant	0	0.75	2e-08	7.69897000433602		1.15	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	17q11.2	17	27779649	NOS2	NOS2			ENSG00000007171	NA	NA	rs4795067-G	rs4795067	0	4795067	intron_variant	0	0.35	4e-11	10.397940008672		1.19	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	20q13.13	20	49905793	RNF114, SLC9A8, SNAI1, SPATA2	SPATA2			ENSG00000158480	NA	NA	rs495337-G	rs495337	0	495337	synonymous_variant	0	0.57	2e-07	6.69897000433602		1.21	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2010-12-01	20953189	Stuart PE	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953189	Genome-wide association analysis identifies three psoriasis susceptibility loci.	Psoriasis	Up to 1,831 cases, up to 2,546 controls	Up to 4,064 cases, up to 4,685 controls	12q13.2	12	56045425	RPS26	RPS26 - ERBB3	ENSG00000197728	ENSG00000065361		728	31374	rs12580100-A	rs12580100	0	12580100	regulatory_region_variant	1	0.90	1e-06	6		1.17	[NR]	Illumina, Perlegen [up to 7456344] (imputed)	N
2011-06-23	21627779	Antunez C	2011-05-31	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21627779	The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.	Alzheimer's disease	319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls	4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls	11q12.2	11	60255614	MS4A	MS4A4A			ENSG00000110079	NA	NA	rs1562990-?	rs1562990	0	1562990	intron_variant	0	0.58	4e-11	10.397940008672		1.14	[1.10-1.18]	Affymetrix, Illumina [696707] (imputed)	N
2011-06-23	21627779	Antunez C	2011-05-31	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21627779	The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.	Alzheimer's disease	319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls	4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls	19q13.32	19	44892009	APOE	TOMM40			ENSG00000130204	NA	NA	rs157580-?	rs157580	0	157580	intron_variant	0	NR	8e-89	88.0969100130081		1.69	[NR]	Affymetrix, Illumina [696707] (imputed)	N
2011-06-23	21627779	Antunez C	2011-05-31	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21627779	The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.	Alzheimer's disease	319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls	4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls	11q14.2	11	86076782	PICALM	PICALM - RNU6-560P	ENSG00000073921	ENSG00000200877		6900	76445	rs536841-?	rs536841	0	536841	intergenic_variant	1	NR	3e-09	8.52287874528034		1.16	[NR]	Affymetrix, Illumina [696707] (imputed)	N
2011-06-23	21627779	Antunez C	2011-05-31	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21627779	The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.	Alzheimer's disease	319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls	4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls	8p21.1	8	27630273	CLU	CLU - SCARA3	ENSG00000120885	ENSG00000168077		15573	3595	rs569214-?	rs569214	0	569214	intergenic_variant	1	NR	4e-08	7.39794000867204		1.14	[NR]	Affymetrix, Illumina [696707] (imputed)	N
2011-06-23	21627779	Antunez C	2011-05-31	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21627779	The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.	Alzheimer's disease	319 European ancestry cases, 769 European ancestry controls, 2,690 cases, 2,237 controls	4,982 European ancestry cases, 7,961 European ancestry controls, 2,190 cases, 3,374 controls	2q14.3	2	127137039	BIN1	BIN1 - AC110926.2	ENSG00000136717	ENSG00000286400		29751	4937	rs744373-?	rs744373	0	744373	regulatory_region_variant	1	NR	2e-09	8.69897000433602		1.18	[NR]	Affymetrix, Illumina [696707] (imputed)	N
2010-08-18	19853236	Ferreira MA	2009-10-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19853236	Sequence variants in three loci influence monocyte counts and erythrocyte volume.	Platelet count	2,538 European ancestry individuals, 3,477 individuals	1,543 individuals	6q23.3	6	135097880	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs9399137-T	rs9399137	0	9399137	intron_variant	0	0.74	1e-09	9		0.16	[0.10-0.22] s.d. decrease	Illumina, Perlegen [~ 2500000] (imputed)	N
2019-08-13	19853236	Ferreira MA	2009-10-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19853236	Sequence variants in three loci influence monocyte counts and erythrocyte volume.	Mean corpuscular hemoglobin	2,538 European ancestry individuals, 3,477 individuals	1,543 individuals	6p22.2	6	25842723	HFE	SLC17A3			ENSG00000124564	NA	NA	rs1408272-T	rs1408272	0	1408272	intron_variant	0	0.94	1e-11	11		0.32	[0.22-0.42] s.d. decrease	Illumina, Perlegen [~ 2500000] (imputed)	N
2019-08-13	19853236	Ferreira MA	2009-10-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19853236	Sequence variants in three loci influence monocyte counts and erythrocyte volume.	Mean corpuscular hemoglobin	2,538 European ancestry individuals, 3,477 individuals	1,543 individuals	22q12.3	22	37073551	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs4820268-A	rs4820268	0	4820268	missense_variant	0	0.53	3e-10	9.52287874528034		0.15	[0.11-0.19] s.d. increase	Illumina, Perlegen [~ 2500000] (imputed)	N
2019-08-13	19853236	Ferreira MA	2009-10-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19853236	Sequence variants in three loci influence monocyte counts and erythrocyte volume.	Mean corpuscular hemoglobin	2,538 European ancestry individuals, 3,477 individuals	1,543 individuals	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-C	rs7775698	0	7775698	intron_variant	0	0.74	5e-13	12.301029995664		0.19	[0.13-0.25] s.d. decrease	Illumina, Perlegen [~ 2500000] (imputed)	N
2019-08-13	19853236	Ferreira MA	2009-10-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19853236	Sequence variants in three loci influence monocyte counts and erythrocyte volume.	Mean corpuscular volume	2,538 European ancestry individuals, 3,477 individuals	1,543 individuals	22q12.3	22	37073551	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs4820268-A	rs4820268	0	4820268	missense_variant	0	0.53	4e-12	11.397940008672		0.13	[0.09-0.17] s.d. increase	Illumina, Perlegen [~ 2500000] (imputed)	N
2019-08-13	19853236	Ferreira MA	2009-10-22	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19853236	Sequence variants in three loci influence monocyte counts and erythrocyte volume.	Mean corpuscular volume	2,538 European ancestry individuals, 3,477 individuals	1,543 individuals	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-C	rs7775698	0	7775698	intron_variant	0	0.74	8e-18	17.0969100130081		0.19	[0.15-0.23] s.d. decrease	Illumina, Perlegen [~ 2500000] (imputed)	N
2011-06-18	21647738	Wu Y	2011-06-07	Inflammation	www.ncbi.nlm.nih.gov/pubmed/21647738	Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.	C-reactive protein	1,709 Filipino ancestry female individuals	NA	1q23.2	1	159705143	CRP	CRPP1			ENSG00000223603	NA	NA	rs876537-C	rs876537	0	876537	non_coding_transcript_exon_variant	0	0.43	1e-09	9		0.288	[0.20-0.38] unit increase	Affymetrix [2073674] (imputed)	N
2011-06-18	21647738	Wu Y	2011-06-07	Inflammation	www.ncbi.nlm.nih.gov/pubmed/21647738	Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.	C-reactive protein	1,709 Filipino ancestry female individuals	NA	12q24.31	12	120965129	HNF1A	HNF1A-AS1			ENSG00000241388	NA	NA	rs7305618-T	rs7305618	0	7305618	intron_variant	0	0.52	1e-08	8		0.267	[0.18-0.36] unit increase	Affymetrix [2073674] (imputed)	N
2011-06-18	21647738	Wu Y	2011-06-07	Inflammation	www.ncbi.nlm.nih.gov/pubmed/21647738	Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.	C-reactive protein	1,709 Filipino ancestry female individuals	NA	6q16.1	6	93142534	NR	AL138731.1 - EPHA7	ENSG00000235099	ENSG00000135333		39150	97486	rs1408282-A	rs1408282	0	1408282	intergenic_variant	1	0.10	1e-06	6		0.412	[0.24-0.58] unit increase	Affymetrix [2073674] (imputed)	N
2010-09-22	20713499	Huang J	2010-08-16	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20713499	Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.	Schizophrenia, bipolar disorder and depression (combined)	402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls	NA	11p15.4	11	10369034	ADM	AMPD3			ENSG00000133805	NA	NA	rs6484218-A	rs6484218	0	6484218	intron_variant	0	0.14	4e-08	7.39794000867204		NA		Affymetrix, Perlegen [1574154] (imputed)	N
2010-09-22	20713499	Huang J	2010-08-16	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20713499	Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.	Schizophrenia, bipolar disorder and depression (combined)	402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls	NA	14q13.1	14	33007060	NPAS3	NPAS3			ENSG00000151322	NA	NA	rs4982029-A	rs4982029	0	4982029	intron_variant	0	0.02	4e-06	5.39794000867204		NA		Affymetrix, Perlegen [1574154] (imputed)	N
2010-09-22	20713499	Huang J	2010-08-16	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20713499	Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.	Schizophrenia, bipolar disorder and depression (combined)	402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls	NA	13q12.11	13	20635373	IFT88	IFT88			ENSG00000032742	NA	NA	rs7326068-A	rs7326068	0	7326068	intron_variant	0	0.19	3e-06	5.52287874528034		NA		Affymetrix, Perlegen [1574154] (imputed)	N
2010-09-22	20713499	Huang J	2010-08-16	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20713499	Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.	Schizophrenia, bipolar disorder and depression (combined)	402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls	NA	9q21.13	9	73149649	ANXA1	ALDH1A1 - ANXA1	ENSG00000165092	ENSG00000135046		69207	2216	rs3758354-C	rs3758354	0	3758354	TF_binding_site_variant	1	0.03	3e-06	5.52287874528034		NA		Affymetrix, Perlegen [1574154] (imputed)	N
2010-09-22	20713499	Huang J	2010-08-16	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20713499	Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression.	Schizophrenia, bipolar disorder and depression (combined)	402 European ancestry schizophrenia cases, 1,021 European ancestry bipolar I cases, 493 European ancestry bipolar II cases, 1,210 European ancestry MDD cases, 1,060 European ancestry controls	NA	22q12.1	22	26007633	MYO18B	MYO18B			ENSG00000133454	NA	NA	rs1001021-A	rs1001021	0	1001021	intron_variant	0	0.02	2e-06	5.69897000433602		NA		Affymetrix, Perlegen [1574154] (imputed)	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	21q21.3	21	25630065	JAM2	MRPL39 - JAM2	ENSG00000154719	ENSG00000154721		22548	9193	rs17001239-?	rs17001239	0	17001239	intergenic_variant	1	0.1166	2e-06	5.69897000433602	(PRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	11p13	11	33847061	LMO2	LINC02721 - LMO2	ENSG00000255133	ENSG00000135363		24683	11515	rs11032423-?	rs11032423	0	11032423	intergenic_variant	1	0.04637	8e-06	5.09691001300806	(IED)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	1q32.1	1	204602943	MDM4	RNA5SP74 - AL512306.3	ENSG00000200408	ENSG00000240710		40422	92	rs12143943-?	rs12143943	0	12143943	intergenic_variant	1	0.413	5e-06	5.30102999566398	(PAL8)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	12q24.31	12	124549387	NCOR2	NCOR2			ENSG00000196498	NA	NA	rs12423712-?	rs12423712	0	12423712	intron_variant	0	0.05907	7e-06	5.15490195998574	(RVP)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	18q12.3	18	42708328	RIT2	LINC00907 - RIT2	ENSG00000267586	ENSG00000152214		16906	34899	rs8085804-?	rs8085804	0	8085804	intergenic_variant	1	0.3695	8e-06	5.09691001300806	(VRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	9p22.1	9	19664083	SLC24A2	SLC24A2			ENSG00000155886	NA	NA	rs4258076-?	rs4258076	0	4258076	intron_variant	0	0.2668	4e-06	5.39794000867204	(VRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	4p13	4	41282694	UCHL1	UCHL1 - Y_RNA	ENSG00000154277	ENSG00000265852		14239	20543	rs4861096-?	rs4861096	0	4861096	intergenic_variant	1	0.244	9e-06	5.04575749056067	(PAL6)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	15q21.3	15	54049268	UNC13C	UNC13C, AC010867.1			ENSG00000137766, ENSG00000259619	NA	NA	rs1897031-?	rs1897031	0	1897031	non_coding_transcript_exon_variant	0	0.1753	1e-06	6	(PRM)	NA		Illumina [475971]	N
2012-11-08	19734545	Need AC	2009-09-04	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/19734545	A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.	Cognitive performance	Up to 1,295 individuals	NA	7p14.1	7	38795435	VPS41	VPS41			ENSG00000006715	NA	NA	rs11984145-?	rs11984145	0	11984145	intron_variant	0	0.0471	6e-06	5.22184874961636	(PAL8)	NA		Illumina [475971]	N
2010-10-15	20872241	Li J	2010-09-26	Breast Cancer Res Treat	www.ncbi.nlm.nih.gov/pubmed/20872241	A combined analysis of genome-wide association studies in breast cancer.	Breast cancer	2,702 European ancestry female cases, 5,726 European ancestry controls	Up to 7,386 cases, 7,576 controls	16q12.1	16	52552429	TOX3	CASC16			ENSG00000249231	NA	NA	rs3803662-A	rs3803662	0	3803662	non_coding_transcript_exon_variant	0	0.30	4e-07	6.39794000867204		1.22	[1.13-1.32]	Illumina [285984]	N
2010-10-15	20872241	Li J	2010-09-26	Breast Cancer Res Treat	www.ncbi.nlm.nih.gov/pubmed/20872241	A combined analysis of genome-wide association studies in breast cancer.	Breast cancer	2,702 European ancestry female cases, 5,726 European ancestry controls	Up to 7,386 cases, 7,576 controls	5p12	5	44874903	MRPS30	AC093297.2 - AC114954.1	ENSG00000272335	ENSG00000248148		46311	160296	rs7716600-A	rs7716600	0	7716600	regulatory_region_variant	1	0.23	7e-07	6.15490195998574		1.24	[1.14-1.34]	Illumina [285984]	N
2010-10-15	20872241	Li J	2010-09-26	Breast Cancer Res Treat	www.ncbi.nlm.nih.gov/pubmed/20872241	A combined analysis of genome-wide association studies in breast cancer.	Breast cancer	2,702 European ancestry female cases, 5,726 European ancestry controls	Up to 7,386 cases, 7,576 controls	2q35	2	217041109	intergenic	AC007749.1 - AC007749.2	ENSG00000259855	ENSG00000287498		44619	19958	rs13387042-?	rs13387042	0	13387042	intergenic_variant	1	0.53	9e-06	5.04575749056067		1.18	[1.10-1.27]	Illumina [285984]	N
2010-10-15	20872241	Li J	2010-09-26	Breast Cancer Res Treat	www.ncbi.nlm.nih.gov/pubmed/20872241	A combined analysis of genome-wide association studies in breast cancer.	Breast cancer	2,702 European ancestry female cases, 5,726 European ancestry controls	Up to 7,386 cases, 7,576 controls	10q26.13	10	121586676	FGFR2	FGFR2			ENSG00000066468	NA	NA	rs1219648-G	rs1219648	0	1219648	intron_variant	0	0.42	2e-13	12.698970004336		1.32	[1.22-1.42]	Illumina [285984]	N
2008-06-22	18463370	Maris JM	2008-05-09	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18463370	Chromosome 6p22 locus associated with clinically aggressive neuroblastoma.	Neuroblastoma	1,032 European ancestry cases, 2,043 European ancestry controls	720 European ancestry cases, 2,128 European ancestry controls	6p22.3	6	22139775	FLJ22536, FLJ44180	CASC15, NBAT1			ENSG00000272168, ENSG00000260455	NA	NA	rs6939340-G	rs6939340	0	6939340	intron_variant	0	0.50	9e-15	14.0457574905607		1.37	[1.27-1.49]	Illumina [464934]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	22q11.23	22	24596299	GGT1	GGT1, GGT1			ENSG00000286070, ENSG00000100031	NA	NA	rs5751901-?	rs5751901	0	5751901	intron_variant	0	0.39	2e-07	6.69897000433602	(GGT1)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	17q25.3	17	82450939	C17orf62	AC132938.6			ENSG00000287193	NA	NA	rs9303029-?	rs9303029	0	9303029	non_coding_transcript_exon_variant	0	0.08	4e-07	6.39794000867204	(Free IGF1)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	19p13.2	19	10102478	ANGPTL6	ANGPTL6			ENSG00000130812	NA	NA	rs8109578-?	rs8109578	0	8109578	intron_variant	0	0.08	4e-07	6.39794000867204	(TSH)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	1p21.1	1	102668353	COL11A1	AC114485.1 - AC099567.1	ENSG00000233359	ENSG00000230864		278723	94969	rs10874639-?	rs10874639	0	10874639	intergenic_variant	1	0.12	3e-06	5.52287874528034	(Fibrinogen)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	1q21.1	1	147383114	CHD1L	LINC00624			ENSG00000278811	NA	NA	rs4950322-?	rs4950322	0	4950322	non_coding_transcript_exon_variant	0	0.21	2e-07	6.69897000433602	(Resistin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	2p12	2	79695676	CTNNA2	CTNNA2			ENSG00000066032	NA	NA	rs11695685-?	rs11695685	0	11695685	intron_variant	0	0.30	5e-07	6.30102999566398	(IL10)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	2p11.2	2	85472627	SH2D6	Y_RNA - RPSAP22	ENSG00000265852	ENSG00000229648		38008	18303	rs7577642-?	rs7577642	0	7577642	regulatory_region_variant	1	0.27	7e-06	5.15490195998574	(sIL-6R)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	6p21.33	6	31303939	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs9461688-?	rs9461688	0	9461688	intron_variant	0	0.31	4e-06	5.39794000867204	(IL18)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	6q22.31	6	121581723	GJA1	RNU2-8P - AL603865.2	ENSG00000222659	ENSG00000220326		1202	59286	rs4541776-?	rs4541776	0	4541776	intergenic_variant	1	0.33	2e-06	5.69897000433602	(GGT)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	6q24.3	6	148466870	SASH1	SASH1			ENSG00000111961	NA	NA	rs6930337-?	rs6930337	0	6930337	intron_variant	0	0.06	1e-06	6	(insulin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	9q31.2	9	105892815	TMEM38B	SLC25A6P5 - LINC01505	ENSG00000228948	ENSG00000234323		41390	100495	rs4742971-?	rs4742971	0	4742971	intergenic_variant	1	0.11	8e-07	6.09691001300806	(GPT (ALT))	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	8q24.21	8	129968226	FAM49B	FAM49B			ENSG00000153310	NA	NA	rs10092658-?	rs10092658	0	10092658	intron_variant	0	0.07	6e-06	5.22184874961636	(Aldolase)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	10p12.31	10	18470700	CACNB2	CACNB2			ENSG00000165995	NA	NA	rs7076247-?	rs7076247	0	7076247	intron_variant	0	0.37	6e-06	5.22184874961636	(CRP)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	11q14.1	11	83744664	DLG2	DLG2			ENSG00000150672	NA	NA	rs3885683-?	rs3885683	0	3885683	intron_variant	0	0.11	8e-06	5.09691001300806	(MCP1)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	15q15.2	15	42692090	CDAN1	STARD9			ENSG00000159433	NA	NA	rs16957063-?	rs16957063	0	16957063	synonymous_variant	0	0.01	5e-07	6.30102999566398	(Ft4)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	15q21.1	15	48340956	DUT	DUT			ENSG00000128951	NA	NA	rs11637235-?	rs11637235	0	11637235	intron_variant	0	0.28	3e-06	5.52287874528034	(Adiponectin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	17q12	17	36463349	CCL4L2	TBC1D3J - ZNHIT3	ENSG00000282656	ENSG00000273611		5814	23280	rs4796217-?	rs4796217	0	4796217	regulatory_region_variant	1	0.34	4e-21	20.397940008672	(MIPb)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	11q23.1	11	112214593	IL18	BCO2			ENSG00000197580	NA	NA	rs2250417-?	rs2250417	0	2250417	intron_variant	0	0.44	7e-13	12.1549019599857	(IL18)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	2p15	2	63369701	LOC51057	WDPCP			ENSG00000143951	NA	NA	rs11683229-?	rs11683229	0	11683229	intron_variant	0	0.15	6e-06	5.22184874961636	(IL6)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	1q21.3	1	154453788	IL6R	IL6R			ENSG00000160712	NA	NA	rs4129267-?	rs4129267	0	4129267	intron_variant	0	0.37	2e-57	56.698970004336	(sIL-6R)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	12q12	12	41327628	CNTN1, PDZRN4	PDZRN4			ENSG00000165966	NA	NA	rs1880887-?	rs1880887	0	1880887	intron_variant	0	0.03	1e-10	10	(Alkaline phosphatase)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	18q11.2	18	24169651	OSBPL1A	OSBPL1A			ENSG00000141447	NA	NA	rs9635963-?	rs9635963	0	9635963	intron_variant	0	0.18	2e-07	6.69897000433602	(SHBG)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	1q23.2	1	159678198	CRP	AL445528.2 - CRPP1	ENSG00000276632	ENSG00000223603		28578	26785	rs12093699-?	rs12093699	0	12093699	intergenic_variant	1	0.29	6e-06	5.22184874961636	(CRP)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	10p11.21	10	36359112	FZD8, ANKRD30A	AL355300.1 - MTND5P17	ENSG00000227475	ENSG00000236626		269723	73770	rs1779876-?	rs1779876	0	1779876	intergenic_variant	1	0.10	3e-06	5.52287874528034	(Lipoprotein A)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	9q22.2	9	90124949	GADD45G, DIRAS2	AL161629.2 - AL353649.1	ENSG00000278382	ENSG00000279503		16431	33079	rs2081670-?	rs2081670	0	2081670	regulatory_region_variant	1	0.15	3e-06	5.52287874528034	(MIP-1b)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	12p12.3	12	15777871	EPS8	EPS8			ENSG00000151491	NA	NA	rs17415853-?	rs17415853	0	17415853	intron_variant	0	0.02	7e-07	6.15490195998574	(Ferritin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	12q24.11	12	110266682	ATP2A2	IFT81 - ATP2A2	ENSG00000122970	ENSG00000174437		47889	14074	rs11065611-?	rs11065611	0	11065611	intergenic_variant	1	0.06	1e-07	7	(Alpha-1 globulin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	13q12.11	13	21913486	FGF3	LINC00424 - AL136962.1	ENSG00000226722	ENSG00000276476		35230	127486	rs17369571-?	rs17369571	0	17369571	intergenic_variant	1	0.16	1e-07	7	(IL1RA)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	13q12.12	13	23329652	SACS	SACS			ENSG00000151835	NA	NA	rs4770433-?	rs4770433	0	4770433	3_prime_UTR_variant	0	0.40	4e-06	5.39794000867204	(IL12)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	9q34.2	9	133273813	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs505922-?	rs505922	0	505922	intron_variant	0	0.34	7e-40	39.1549019599857	(TNFA)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	17p13.1	17	7514346	SHBG	POLR2A, POLR2A			ENSG00000181222, ENSG00000284832	NA	NA	rs6761-?	rs6761	0	6761	3_prime_UTR_variant	0	0.31	3e-07	6.52287874528034	(SHBG)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	2q14.1	2	113074735	IL1RN	IL1F10			ENSG00000136697	NA	NA	rs6761276-?	rs6761276	0	6761276	missense_variant	0	0.37	7e-06	5.15490195998574	(IL1RA)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	1q21.1	1	147383114	CHD1L	LINC00624			ENSG00000278811	NA	NA	rs4950322-?	rs4950322	0	4950322	non_coding_transcript_exon_variant	0	0.21	7e-07	6.15490195998574	(Hgb)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	2p13.2	2	71731350	DYSF	DYSF - RPS20P10	ENSG00000135636	ENSG00000233971		44582	252832	rs2900976-?	rs2900976	0	2900976	intergenic_variant	1	0.30	1e-06	6	(Albumin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	3p12.3	3	78449847	ROBO1	AC108752.1 - MRPS17P3	ENSG00000240241	ENSG00000239226		155116	75254	rs9834373-?	rs9834373	0	9834373	intergenic_variant	1	0.17	4e-06	5.39794000867204	(GP130)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	2q23.1	2	148630399	EPC2	RPS29P8 - EPC2	ENSG00000232238	ENSG00000135999		35071	14041	rs10191411-?	rs10191411	0	10191411	intergenic_variant	1	0.32	4e-06	5.39794000867204	(IL8)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	5q35.1	5	169647052	DOCK2	DOCK2			ENSG00000134516	NA	NA	rs169082-?	rs169082	0	169082	intron_variant	0	0.48	1e-06	6	(Leptin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	6q11.1	6	61987841	KHDRBS2	KHDRBS2			ENSG00000112232	NA	NA	rs6455128-?	rs6455128	0	6455128	intron_variant	0	0.19	3e-07	6.52287874528034	(GOT (AST))	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	6q23.2	6	133539207	EYA4	TARID			ENSG00000227954	NA	NA	rs9402515-?	rs9402515	0	9402515	intron_variant	0	0.09	1e-06	6	(Alpha-2 macroglobulin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	8q21.12	8	74600899	GDAP1, PI15	MIR2052HG			ENSG00000254349	NA	NA	rs6472866-?	rs6472866	0	6472866	intron_variant	0	0.42	8e-07	6.09691001300806	(myoglobin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	7p21.3	7	9226758	NXPH1	AC004852.2 - GAPDHP68	ENSG00000278254	ENSG00000233876		36901	388220	rs1285407-?	rs1285407	0	1285407	intergenic_variant	1	0.35	1e-06	6	(TGF-b1)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	11p15.5	11	2745052	KCNQ1	KCNQ1			ENSG00000053918	NA	NA	rs2237878-?	rs2237878	0	2237878	intron_variant	0	0.07	1e-06	6	(Lactic dehydrogenase)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	11q24.2	11	126939809	KIRREL3	KIRREL3, AP002833.1			ENSG00000149571, ENSG00000254938	NA	NA	rs1939992-?	rs1939992	0	1939992	intron_variant	0	0.26	1e-06	6	(Total IGF-1)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	12q24.33	12	131455375	GPR133	AC073578.2			ENSG00000275232	NA	NA	rs10466868-?	rs10466868	0	10466868	intron_variant	0	0.12	1e-06	6	(Erythropoeitin)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	11q23.3	11	117166645	PAFAH1B2	PAFAH1B2			ENSG00000168092	NA	NA	rs7112513-?	rs7112513	0	7112513	intron_variant	0	0.13	6e-09	8.22184874961636	(Soluble transferrin receptor)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	6q25.3	6	160597142	LPA	LPA			ENSG00000198670	NA	NA	rs7770628-?	rs7770628	0	7770628	intron_variant	0	0.49	4e-10	9.39794000867204	(LPA)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	16q23.2	16	81270154	BCM01	BCO1			ENSG00000135697	NA	NA	rs4889294-?	rs4889294	0	4889294	splice_region_variant	0	0.47	5e-07	6.30102999566398	(IL1B)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	17p12	17	14390704	HS3ST3B1	AC022816.1			ENSG00000230647	NA	NA	rs3848445-?	rs3848445	0	3848445	intron_variant	0	0.05	8e-09	8.09691001300806	(Ft3)	NA		Illumina [496032]	N
2008-06-22	18464913	Melzer D	2008-05-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18464913	A genome-wide association study identifies protein quantitative trait loci (pQTLs).	Protein quantitative trait loci	1,200 European ancestry individuals	up to 4,590 European ancestry individuals	18q12.1	18	30561722	DSC3	AC115100.1 - AC090506.1	ENSG00000286605	ENSG00000266196		147649	151553	rs2729409-?	rs2729409	0	2729409	intergenic_variant	1	0.26	3e-06	5.52287874528034	(Parathyroid hormone)	NA		Illumina [496032]	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	11q13.5	11	76588150	LRRC32, C11orf30	EMSY - AP001189.2	ENSG00000158636	ENSG00000254755		35125	2873	rs2155219-T	rs2155219	0	2155219	intergenic_variant	1	0.47	1e-08	8		1.22	[1.14-1.31]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	5q22.1	5	110810746	TMEM232, SLCA25A46	SLC25A46 - AC008782.1	ENSG00000164209	ENSG00000270779		45585	97538	rs17513503-G	rs17513503	0	17513503	intergenic_variant	1	0.09	1e-08	8		1.39	[1.24-1.56]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	4q27	4	122451978	IL2	IL2			ENSG00000109471	NA	NA	rs2069772-C	rs2069772	0	2069772	intron_variant	0	0.30	1e-06	6		1.19	[1.11-1.28]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	16p13.2	16	9305867	intergenic	RPL21P119 - LINC02177	ENSG00000220793	ENSG00000261617		148986	49721	rs631208-A	rs631208	0	631208	intergenic_variant	1	0.60	2e-06	5.69897000433602		1.18	[1.10-1.26]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	1p32.3	1	51393570	EPS15	EPS15			ENSG00000085832	NA	NA	rs6673480-T	rs6673480	0	6673480	intron_variant	0	0.07	2e-06	5.69897000433602		1.35	[1.19-1.52]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	5p15.2	5	13740867	DNAH5	DNAH5			ENSG00000039139	NA	NA	rs6554809-C	rs6554809	0	6554809	intron_variant	0	0.84	3e-06	5.52287874528034		1.29	[1.16-1.43]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	3q22.1	3	133009059	TMEM108	NPHP3-AS1 - AC079942.1	ENSG00000248724	ENSG00000249725		134836	5945	rs7617456-G	rs7617456	0	7617456	intergenic_variant	1	0.59	3e-06	5.52287874528034		1.18	[1.10-1.26]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	1q25.2	1	179102621	ABL2	ABL2			ENSG00000143322	NA	NA	rs1325195-A	rs1325195	0	1325195	3_prime_UTR_variant	0	0.59	5e-06	5.30102999566398		1.17	[1.10-1.26]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	IgE grass sensitization	2,315 European ancestry cases, 10,032 European ancestry controls	NA	6p21.32	6	32690302	HLA region	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		21919	15822	rs7775228-C	rs7775228	0	7775228	TF_binding_site_variant	1	0.13	2e-09	8.69897000433602		1.33	[1.21-1.45]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	20p11.21	20	25226018	ENTPD6	ENTPD6			ENSG00000197586	NA	NA	rs1044573-A	rs1044573	0	1044573	3_prime_UTR_variant	0	0.51	1e-06	6		1.15	[1.09-1.21]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	5q23.1	5	116639960	SEMA6A	SEMA6A-AS2 - RPS17P2	ENSG00000249167	ENSG00000197575		28760	76283	rs6898653-G	rs6898653	0	6898653	intergenic_variant	1	0.22	1e-06	6		1.23	[1.13-1.34]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	16p13.13	16	11065028	CLEC16A	CLEC16A			ENSG00000038532	NA	NA	rs887864-A	rs887864	0	887864	intron_variant	0	0.63	1e-06	6		1.16	[1.09-1.23]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	11q13.5	11	76588150	LRRC32, C11orf30	EMSY - AP001189.2	ENSG00000158636	ENSG00000254755		35125	2873	rs2155219-T	rs2155219	0	2155219	intergenic_variant	1	0.47	4e-08	7.39794000867204		1.17	[1.11-1.24]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	5q22.1	5	110810746	TMEM232, SLCA25A46	SLC25A46 - AC008782.1	ENSG00000164209	ENSG00000270779		45585	97538	rs17513503-G	rs17513503	0	17513503	intergenic_variant	1	0.09	7e-07	6.15490195998574		1.28	[1.16-1.41]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	14q23.1	14	60216712	PPM1A, DHRS7	RPL17P2 - AL157756.1	ENSG00000242135	ENSG00000254718		3800	23409	rs216518-A	rs216518	0	216518	intergenic_variant	1	0.15	2e-06	5.69897000433602		1.21	[1.12-1.31]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	1p36.13	1	16889836	CROCC	CROCC			ENSG00000058453	NA	NA	rs6586513-C	rs6586513	0	6586513	intron_variant	0	0.29	4e-06	5.39794000867204		1.24	[1.13-1.36]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	5q22.1	5	111072304	TSLP	TSLP			ENSG00000145777	NA	NA	rs1898671-T	rs1898671	0	1898671	intron_variant	0	0.35	5e-06	5.30102999566398		1.15	[1.08-1.22]	Affymetrix, Illumina [2217510] (imputed)	N
2011-12-01	22036096	Ramasamy A	2011-11-01	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/22036096	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	Allergic rhinitis	3,933 European ancestry cases, 8,965 European ancestry controls	NA	7p14.1	7	42225080	GLI3	GLI3			ENSG00000106571	NA	NA	rs4724100-C	rs4724100	0	4724100	intron_variant	0	0.45	2e-06	5.69897000433602		1.14	[1.08-1.21]	Affymetrix, Illumina [2217510] (imputed)	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	2q37.1	2	233274722	ATG16L1	ATG16L1, ATG16L1			ENSG00000085978, ENSG00000281089	NA	NA	rs2241880-?	rs2241880	0	2241880	missense_variant	0	NR	3e-06	5.52287874528034		1.32	[1.18-1.47]	Illumina [304825]	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	16q12.1	16	50729868	NOD2	AC007728.2, NOD2			ENSG00000261644, ENSG00000167207	NA	NA	rs2066847-?	rs2066847	0	2066847	frameshift_variant	0	NR	2e-15	14.698970004336		1.62	[1.42-1.86]	Illumina [304825]	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	19q13.33	19	48705608	FUT2	FUT2			ENSG00000176920	NA	NA	rs504963-A	rs504963	0	504963	3_prime_UTR_variant	0	0.431	2e-08	7.69897000433602		NA		Illumina [304825]	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	1p31.3	1	67236843	IL23R	IL23R			ENSG00000162594	NA	NA	rs11465804-?	rs11465804	0	11465804	intron_variant	0	NR	1e-06	6		1.89	[1.47-2.44]	Illumina [304825]	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	5q31.1	5	132435113	IBD5	C5orf56, AC116366.3			ENSG00000197536, ENSG00000283782	NA	NA	rs2188962-?	rs2188962	0	2188962	intron_variant	0	NR	1e-07	7		1.36	[1.21-1.52]	Illumina [304825]	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	5q33.3	5	159387525	IL12B	AC008691.1			ENSG00000249738	NA	NA	rs10045431-?	rs10045431	0	10045431	intron_variant	0	NR	7e-08	7.15490195998574		1.45	[1.27-1.64]	Illumina [304825]	N
2010-07-12	20570966	McGovern DP	2010-06-22	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20570966	Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.	Crohn's disease	896 European ancestry cases, 3,204 European ancestry controls	1,174 European ancestry cases, 357 European ancestry controls	6q27	6	167024500	FGFR10P, RNASE2, CCR6	FGFR1OP, Z94721.2			ENSG00000213066, ENSG00000272980	NA	NA	rs2301436-?	rs2301436	0	2301436	intron_variant	0	NR	6e-08	7.22184874961636		1.37	[1.22-1.53]	Illumina [304825]	N
2008-06-18	18471798	Valdes AM	2008-05-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18471798	Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis.	Knee osteoarthritis	357 European ancestry cases, 285 European ancestry controls	1,177 European ancestry cases, 2,372 European ancestry controls	1q31.1	1	186755871	PTGS2, PLA2G4A	PACERR - PLA2G4A	ENSG00000273129	ENSG00000116711		74425	73078	rs4140564-?	rs4140564	0	4140564	intergenic_variant	1	0.05	3e-06	5.52287874528034		1.59	[1.31-1.94]	Illumina [413461]	N
2008-06-18	18471798	Valdes AM	2008-05-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18471798	Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis.	Knee osteoarthritis	357 European ancestry cases, 285 European ancestry controls	1,177 European ancestry cases, 2,372 European ancestry controls	2q33.3	2	205285870	PARD3B	PARD3B			ENSG00000116117	NA	NA	rs1207421-?	rs1207421	0	1207421	intron_variant	0	0.09	6e-06	5.22184874961636		1.46	[1.24-1.73]	Illumina [413461]	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	6q16.3	6	104931079	LIN28B	LIN28B-AS1			ENSG00000203809	NA	NA	rs7759938-C	rs7759938	0	7759938	intron_variant	0	0.32	4e-09	8.39794000867204	(Late pubertal growth)	0.11	[0.079-0.141] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	6p21.31	6	34796205	C6orf106	UHRF1BP1			ENSG00000065060	NA	NA	rs9469890-C	rs9469890	0	9469890	intron_variant	0	0.88	9e-08	7.04575749056067	(Pubertal growth)	0.12	[0.077-0.163] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	2p23.3	2	24946331	ADCY3, DNAJC27, POMC	DNAJC27			ENSG00000115137	NA	NA	rs1172294-G	rs1172294	0	1172294	3_prime_UTR_variant	0	0.45	1e-08	8	(Pubertal growth)	0.08	[0.053-0.107] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	3p12.1	3	86801468	VGLL3	LINC02070 - AC108706.1	ENSG00000241328	ENSG00000277746		304472	15272	rs7628864-G	rs7628864	0	7628864	intergenic_variant	1	0.38	3e-09	8.52287874528034	(Pubertal growth, females)	0.11	[0.073-0.147] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	9q31.3	9	111531354	ZNF483	ZNF483			ENSG00000173258	NA	NA	rs10980926-G	rs10980926	0	10980926	intron_variant	0	0.65	2e-07	6.69897000433602	(Pubertal growth)	0.07	[0.043-0.097] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	6p21.32	6	32415273	TAP2, HLA-DRA	TSBP1-AS1 - HLA-DRA	ENSG00000225914	ENSG00000234794		7510	24605	rs4959027-G	rs4959027	0	4959027	regulatory_region_variant	1	0.82	9e-07	6.04575749056067	(Pubertal growth)	0.09	[0.057-0.123] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	4q21.21	4	81223772	BMP3, PRKG2	PRKG2 - RNU5A-2P	ENSG00000138669	ENSG00000207065		8655	110531	rs1662853-C	rs1662853	0	1662853	intergenic_variant	1	0.76	1e-07	7	(Pubertal growth)	0.08	[0.051-0.109] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	12q22	12	93589778	SOCS2	SOCS2 - AC012085.1	ENSG00000120833	ENSG00000186076		6291	51044	rs7953508-C	rs7953508	0	7953508	intergenic_variant	1	0.72	4e-06	5.39794000867204	(Pubertal growth)	0.07	[0.041-0.099] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	6p21.33	6	31392478	MICA, VARS2	HLA-S - AL645933.2	ENSG00000228179	ENSG00000272221		10190	1811	rs7751505-C	rs7751505	0	7751505	intergenic_variant	1	0.28	4e-06	5.39794000867204	(Pubertal growth)	0.07	[0.041-0.099] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	13q14.3	13	50532652	DLEU7	DLEU1, DLEU7			ENSG00000176124, ENSG00000186047	NA	NA	rs3118906-G	rs3118906	0	3118906	intron_variant	0	0.69	5e-06	5.30102999566398	(Pubertal growth)	0.07	[0.043-0.097] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	1p31.1	1	74527379	TNNI3K	FPGT-TNNI3K, TNNI3K			ENSG00000259030, ENSG00000116783	NA	NA	rs1514174-C	rs1514174	0	1514174	intron_variant	0	0.47	6e-06	5.22184874961636	(Pubertal growth, females)	0.08	[0.045-0.115] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	9q31.3	9	111531354	ZNF483	ZNF483			ENSG00000173258	NA	NA	rs10980926-G	rs10980926	0	10980926	intron_variant	0	0.65	3e-06	5.52287874528034	(Pubertal growth,males)	0.1	[0.059-0.141] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	6q16.3	6	104916546	LIN28B	LIN28B-AS1			ENSG00000203809	NA	NA	rs11156429-G	rs11156429	0	11156429	intron_variant	0	0.55	2e-07	6.69897000433602	(Late pubertal growth, females)	0.11	[0.071-0.149] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	up to 5,043 European ancestry males, up to 5,756 European ancestry females	NA	9q31.2	9	106204807	TMEM38B	LINC01505			ENSG00000234323	NA	NA	rs2090409-C	rs2090409	0	2090409	intron_variant	0	0.66	2e-06	5.69897000433602	(Late pubertal growth, males)	0.11	[0.065-0.155] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	16p11.2	16	29956113	MAPK3	TMEM219			ENSG00000149932	NA	NA	rs4788196-G	rs4788196	0	4788196	intron_variant	0	0.44	9e-11	10.0457574905607	(Single Height)	0.07	[0.048-0.092] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	1q32.1	1	205720679	NUCKS1, RAB7L1	NUCKS1			ENSG00000069275	NA	NA	rs823094-G	rs823094	0	823094	intron_variant	0	0.43	2e-07	6.69897000433602	(Single Height)	0.05	[0.03-0.07] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	9q21.12	9	70542500	TRPM3	TRPM3			ENSG00000083067	NA	NA	rs10780944-G	rs10780944	0	10780944	intron_variant	0	0.19	8e-07	6.09691001300806	(Single Height-males)	0.09	[0.053-0.127] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	12q24.31	12	123600955	DDX55	TMED2 - DDX55	ENSG00000086598	ENSG00000111364		2373	1122	rs786425-G	rs786425	0	786425	regulatory_region_variant	1	0.4	3e-06	5.52287874528034	(Single Height)	0.06	[0.038-0.082] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	12p12.3	12	14813670	C12orf60, HIST4H4	SMCO3, C12orf60			ENSG00000179256, ENSG00000182993	NA	NA	rs4764124-C	rs4764124	0	4764124	intron_variant	0	0.52	8e-07	6.09691001300806	(Single Height)	0.05	[0.03-0.07] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	6p22.1	6	28162011	ZNF	ZNF192P1			ENSG00000226314	NA	NA	rs1150668-G	rs1150668	0	1150668	intron_variant	0	0.43	2e-07	6.69897000433602	(Single Height)	0.06	[0.038-0.082] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	11q22.1	11	102138549	YAP1	YAP1			ENSG00000137693	NA	NA	rs11225148-G	rs11225148	0	11225148	intron_variant	0	0.06	2e-06	5.69897000433602	(Single Height)	0.1	[0.051-0.149] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	1p31.1	1	76011522	ST6	AC092813.1			ENSG00000225605	NA	NA	rs12122440-C	rs12122440	0	12122440	intron_variant	0	0.16	2e-06	5.69897000433602	(Single Height)	0.08	[0.049-0.111] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	5q35.3	5	178999318	GRM6	AC104117.4 - ZNF879	ENSG00000254158	ENSG00000234284		503	24486	rs11249608-C	rs11249608	0	11249608	intergenic_variant	1	0.69	6e-07	6.22184874961636	(Single Height-female)	0.08	[0.049-0.111] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	1p32.2	1	57160259	DAB1	DAB1			ENSG00000173406	NA	NA	rs17541203-C	rs17541203	0	17541203	intron_variant	0	0.082	2e-06	5.69897000433602	(Single Height-female)	0.13	[0.073-0.187] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-05-31	23449627	Cousminer DL	2013-02-27	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23449627	Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.	Pubertal anthropometrics	7,161 European ancestry males, 6,879 European ancestry females	5,133 European ancestry males, 4,577 European ancestry females	19q13.33	19	48711017	MAMSTR	FUT2 - MAMSTR	ENSG00000176920	ENSG00000176909		5066	1708	rs281379-G	rs281379	0	281379	intergenic_variant	1	0.52	5e-08	7.30102999566398	(Single Height-males)	0.07	[0.043-0.097] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-06-14	19465909	Jallow M	2009-05-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19465909	Genome-wide and fine-resolution association analysis of malaria in West Africa.	Malaria	958 Gambian ancestry cases, 1,382 Gambian ancestry controls	1,087 Gambian ancestry cases, 2,376 Gambian ancestry controls	7p12.1	7	50555014	DDC	DDC			ENSG00000132437	NA	NA	rs1451375-?	rs1451375	0	1451375	intron_variant	0	0.78	6e-06	5.22184874961636		1.33	[1.18-1.52]	Affymetrix [402814]	N
2009-06-14	19465909	Jallow M	2009-05-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19465909	Genome-wide and fine-resolution association analysis of malaria in West Africa.	Malaria	958 Gambian ancestry cases, 1,382 Gambian ancestry controls	1,087 Gambian ancestry cases, 2,376 Gambian ancestry controls	17p13.1	17	10670842	SCO1	AC002347.1 - SCO1	ENSG00000261433	ENSG00000133028		11760	1632	rs6503319-T	rs6503319	0	6503319	intergenic_variant	1	0.45	7e-07	6.15490195998574		1.21	[1.12-1.31]	Affymetrix [402814]	N
2009-06-14	19465909	Jallow M	2009-05-24	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19465909	Genome-wide and fine-resolution association analysis of malaria in West Africa.	Malaria	958 Gambian ancestry cases, 1,382 Gambian ancestry controls	1,087 Gambian ancestry cases, 2,376 Gambian ancestry controls	11p15.4	11	5204405	HBB	OR51V1 - AC104389.2	ENSG00000176742	ENSG00000224091		3705	636	rs11036238-?	rs11036238	0	11036238	regulatory_region_variant	1	0.14	4e-11	10.397940008672		1.59	[1.39-1.82]	Affymetrix [402814]	N
2008-07-30	18604267	Pare G	2008-07-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18604267	Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.	Soluble ICAM-1	4,570 European ancestry female individuals	2,008 European ancestry female individuals	19p13.2	19	10284116	ICAM1	AC011511.2, ICAM1			ENSG00000266978, ENSG00000090339	NA	NA	rs1799969-A	rs1799969	0	1799969	missense_variant	0	0.12	4e-47	46.397940008672		28.19	[NR] umol/L decrease	Illumina [336108]	N
2008-07-30	18604267	Pare G	2008-07-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18604267	Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.	Soluble ICAM-1	4,570 European ancestry female individuals	2,008 European ancestry female individuals	19p13.2	19	10285007	ICAM1	ICAM1, AC011511.2			ENSG00000090339, ENSG00000266978	NA	NA	rs5498-A	rs5498	0	5498	missense_variant	0	0.43	5e-25	24.301029995664		13.22	[NR] umol/L increase	Illumina [336108]	N
2008-07-30	18604267	Pare G	2008-07-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18604267	Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.	Soluble ICAM-1	4,570 European ancestry female individuals	2,008 European ancestry female individuals	19p13.2	19	10286562	ICAM1	ICAM1, AC011511.5			ENSG00000090339, ENSG00000267607	NA	NA	rs281437-?	rs281437	0	281437	3_prime_UTR_variant	0	0.30	3e-10	9.52287874528034		10.1	[NR] umol/L increase	Illumina [336108]	N
2008-07-30	18604267	Pare G	2008-07-04	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18604267	Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.	Soluble ICAM-1	4,570 European ancestry female individuals	2,008 European ancestry female individuals	9q34.2	9	133273983	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs507666-G	rs507666	0	507666	intron_variant	0	0.20	5e-29	28.301029995664		17.73	[NR] umol/L decrease	Illumina [336108]	N
2010-10-15	20876420	Ingle JN	2010-09-27	J Clin Oncol	www.ncbi.nlm.nih.gov/pubmed/20876420	Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.	Adverse response to aromatase inhibitors	293 cases, 585 controls	NA	14q32.13	14	95702794	TCL1A	AL133467.3 - TCL1A	ENSG00000259084	ENSG00000100721		10164	7153	rs7158782-?	rs7158782	0	7158782	intergenic_variant	1	0.11	8e-07	6.09691001300806		2.13	[1.58-2.87]	Illumina [551395]	N
2011-01-11	21139019	Walsh KM	2010-12-07	Endocr Relat Cancer	www.ncbi.nlm.nih.gov/pubmed/21139019	A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.	Ileal carcinoids	239 European ancestry cases, 107 European ancestry controls	NA	3q28	3	192179429	FGF12	FGF12			ENSG00000114279	NA	NA	rs975121-?	rs975121	0	975121	intron_variant	0	NR	7e-06	5.15490195998574		2.17	[1.55-3.03]	Illumina [308330]	N
2011-01-11	21139019	Walsh KM	2010-12-07	Endocr Relat Cancer	www.ncbi.nlm.nih.gov/pubmed/21139019	A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.	Ileal carcinoids	239 European ancestry cases, 107 European ancestry controls	NA	6p22.3	6	20694653	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs2206734-?	rs2206734	0	2206734	intron_variant	0	NR	8e-06	5.09691001300806		3.45	[2.08-5.56]	Illumina [308330]	N
2011-01-11	21139019	Walsh KM	2010-12-07	Endocr Relat Cancer	www.ncbi.nlm.nih.gov/pubmed/21139019	A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.	Ileal carcinoids	239 European ancestry cases, 107 European ancestry controls	NA	5q23.3	5	128186851	SLC12A2	SLC12A2			ENSG00000064651	NA	NA	rs10089-?	rs10089	0	10089	3_prime_UTR_variant	0	NR	2e-06	5.69897000433602		2.56	[1.79-3.70]	Illumina [308330]	N
2011-01-11	21139019	Walsh KM	2010-12-07	Endocr Relat Cancer	www.ncbi.nlm.nih.gov/pubmed/21139019	A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum.	Ileal carcinoids	239 European ancestry cases, 107 European ancestry controls	NA	20p12.1	20	16330665	KIF16B	KIF16B			ENSG00000089177	NA	NA	rs2208059-?	rs2208059	0	2208059	intron_variant	0	NR	4e-07	6.39794000867204		2.42	[1.72-3.42]	Illumina [308330]	N
2009-06-10	19456320	Ma D	2009-05-28	Ann Hum Genet	www.ncbi.nlm.nih.gov/pubmed/19456320	A genome-wide association study of autism reveals a common novel risk locus at 5p14.1.	Autism	1,390 European ancestry individuals from 438 families	2,390 European ancestry individuals from 457 families	5p14.1	5	25902233	intergenic	AC022418.1 - MSNP1	ENSG00000279869	ENSG00000251593		185518	7270	rs10038113-T	rs10038113	0	10038113	intergenic_variant	1	0.59	3e-06	5.52287874528034		1.33	[1.11-1.43]	Illumina [775311]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	9p21.2	9	27490969	IFNK	MOB3B			ENSG00000120162	NA	NA	rs7046653-A	rs7046653	0	7046653	intron_variant	0	0.26	5e-07	6.30102999566398		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	2q24.3	2	168532581	LASS6	CERS6			ENSG00000172292	NA	NA	rs13393173-A	rs13393173	0	13393173	intron_variant	0	0.12	4e-06	5.39794000867204		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	20p11.21	20	23866372	CST5	CST2 - CST5	ENSG00000170369	ENSG00000170367		39643	9562	rs6138150-T	rs6138150	0	6138150	intergenic_variant	1	0.84	3e-06	5.52287874528034		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	1p22.3	1	87666697	LMO4	PKN2-AS1			ENSG00000237505	NA	NA	rs983332-A	rs983332	0	983332	intron_variant	0	0.21	5e-06	5.30102999566398		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	4p15.1	4	35370476	CENTD1	AC020589.1 - SEC63P2	ENSG00000238694	ENSG00000250416		404132	117336	rs437943-G	rs437943	0	437943	intergenic_variant	1	0.33	4e-06	5.39794000867204		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	7q21.3	7	95301079	PON1	PON1			ENSG00000005421	NA	NA	rs854555-A	rs854555	0	854555	intron_variant	0	0.34	2e-06	5.69897000433602		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	6q26	6	163765645	QKI	AL078602.1			ENSG00000235538	NA	NA	rs10945919-G	rs10945919	0	10945919	intron_variant	0	0.32	3e-07	6.52287874528034		NA		Illumina [283348]	N
2008-08-07	18615156	Liu C	2008-07-10	Mol Med	www.ncbi.nlm.nih.gov/pubmed/18615156	Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.	Response to TNF antagonist treatment	89 European ancestry cases	NA	20q12	20	40192165	MAFB	AL009050.1 - MAFB	ENSG00000223410	ENSG00000204103		65808	493683	rs6028945-T	rs6028945	0	6028945	regulatory_region_variant	1	0.12	2e-07	6.69897000433602		NA		Illumina [283348]	N
2012-01-10	22171074	Tan A	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22171074	A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.	Triglycerides	1,999 Han Chinese ancestry male individuals	1,496 Han Chinese ancestry male individuals	8p21.3	8	19962213	LPL	LPL			ENSG00000175445	NA	NA	rs328-?	rs328	0	328	stop_gained	0	NR	1e-09	9		NA		Illumina [1940243] (imputed)	N
2012-01-10	22171074	Tan A	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22171074	A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.	Triglycerides	1,999 Han Chinese ancestry male individuals	1,496 Han Chinese ancestry male individuals	11q23.3	11	116791863	APOA5	APOA5			ENSG00000110243	NA	NA	rs651821-?	rs651821	0	651821	5_prime_UTR_variant	0	NR	9e-26	25.0457574905607		NA		Illumina [1940243] (imputed)	N
2012-01-10	22171074	Tan A	2011-12-30	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/22171074	A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.	Triglycerides	1,999 Han Chinese ancestry male individuals	1,496 Han Chinese ancestry male individuals	12q24.12	12	111803962	ALDH2	ALDH2			ENSG00000111275	NA	NA	rs671-?	rs671	0	671	missense_variant	0	NR	2e-06	5.69897000433602		NA		Illumina [1940243] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	1p36.32	1	2622185	MMEL1, TNFRSF14	MMEL1, MMEL1			ENSG00000142606, ENSG00000277131	NA	NA	rs3890745-T	rs3890745	0	3890745	intron_variant	0	0.67	1e-07	7		1.12	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	7q21.2	7	92617430	CDK6	CDK6			ENSG00000105810	NA	NA	rs42041-G	rs42041	0	42041	intron_variant	0	0.24	4e-06	5.39794000867204		1.11	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	20q13.12	20	46119308	CD40	CD40			ENSG00000101017	NA	NA	rs4810485-G	rs4810485	0	4810485	intron_variant	0	0.75	8e-09	8.09691001300806		1.15	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	1p13.2	1	113761186	PTPN22	PHTF1 - RSBN1	ENSG00000116793	ENSG00000081019		1697	646	rs6679677-?	rs6679677	0	6679677	intergenic_variant	1	0.10	6e-42	41.2218487496164		1.79	[1.65-1.94]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	6p21.32	6	32696222	HLA-DRB1	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		27839	9902	rs6457620-?	rs6457620	0	6457620	intergenic_variant	1	0.50	4e-186	185.397940008672		2.55	[2.40-2.71]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	6q23.3	6	137685367	TNFIP3, OLIG3	AL356234.2			ENSG00000230533	NA	NA	rs6920220-?	rs6920220	0	6920220	intron_variant	0	0.22	2e-09	8.69897000433602		1.24	[1.16-1.32]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	10p15.1	10	6351298	PRKCQ	LINC02649, LINC02656			ENSG00000215244, ENSG00000212743	NA	NA	rs4750316-G	rs4750316	0	4750316	non_coding_transcript_exon_variant	0	0.20	4e-06	5.39794000867204		1.14	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	9p13.3	9	34710263	CCL21	AL162231.2			ENSG00000230074	NA	NA	rs2812378-G	rs2812378	0	2812378	intron_variant	0	0.34	3e-08	7.52287874528034		1.12	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
2008-09-25	18794853	Raychaudhuri S	2008-09-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18794853	Common variants at CD40 and other loci confer risk of rheumatoid arthritis.	Rheumatoid arthritis	3,393 European ancestry cases, 12,460 European ancestry controls	3,929 European ancestry cases, 5,807 European ancestry controls	12q13.3	12	57574932	KIF5A, PIP4K2C	KIF5A			ENSG00000155980	NA	NA	rs1678542-C	rs1678542	0	1678542	intron_variant	0	0.37	9e-08	7.04575749056067		1.12	[NR]	Affymetrix, Illumina [at least 315971] (imputed)	N
2011-12-17	22101970	Kho AN	2011-11-19	J Am Med Inform Assoc	www.ncbi.nlm.nih.gov/pubmed/22101970	Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study.	Type 2 diabetes	2,413 European ancestry cases, 2,392 European ancestry controls, 810 African American cases, 873 African American controls	NA	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	0	0.26 (EA+AA)	2e-15	14.698970004336		1.46	[NR]	Illumina [NR]	N
2008-10-14	18820697	Miyagawa T	2008-09-28	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18820697	Variant between CPT1B and CHKB associated with susceptibility to narcolepsy.	Narcolepsy	222 Japanese ancestry cases, 389 Japanese ancestry controls	274 East Asian ancestry cases, 499 East Asian ancestry controls, 388 European ancestry cases, 397 European ancestry controls, 86 African American cases, 98 African American controls	22q13.33	22	50578924	CPT1B	CHKB-CPT1B			ENSG00000254413	NA	NA	rs5770917-C	rs5770917	0	5770917	intron_variant	0	0.17	6e-08	7.22184874961636		1.63	[1.37-1.95]	Affymetrix [249133]	N
2009-05-21	19421330	Yang HC	2009-05-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/19421330	Genome-wide association study of young-onset hypertension in the Han Chinese population of Taiwan.	Hypertension (young onset)	175 Han Chinese ancestry cases, 175 Han Chinese ancestry controls	833 Han Chinese ancestry cases, 833 Han Chinese ancestry controls	2p22.3	2;2;2;2	34080190;34059785;34060127;34059917	LOC344371, MYADML, FAM98A, RASGRP3	LINC01320; LINC01320; LINC01320; LINC01320				NA	NA	rs10495809-?; rs9308945-?; rs6729869-?; rs6711736-?	rs10495809; rs9308945; rs6729869; rs6711736	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	3e-10	9.52287874528034		NA		Affymetrix [91713]	N
2008-12-09	18987618	Cronin S	2008-11-05	Eur J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18987618	Screening for replication of genome-wide SNP associations in sporadic ALS.	Amyotrophic lateral sclerosis	958 European ancestry cases, 932 European ancestry controls	309 European ancestry cases, 404 European ancestry controls	7q36.2	7	154513713	DPP6	DPP6			ENSG00000130226	NA	NA	rs10260404-C	rs10260404	0	10260404	intron_variant	0	0.35	3e-06	5.52287874528034		1.37	[1.20-1.56]	Illumina [287522]	N
2008-12-09	18991354	Gretarsdottir S	2008-10-01	Ann Neurol	www.ncbi.nlm.nih.gov/pubmed/18991354	Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.	Stroke (ischemic)	1,661 European ancestry cases, 10,815 European ancestry controls	4,576 European ancestry cases, 19,343 European ancestry controls	4q25	4	110789013	NR	PITX2 - LINC01438	ENSG00000164093	ENSG00000249519		146890	5390	rs2200733-T	rs2200733	0	2200733	intergenic_variant	1	0.11	2e-10	9.69897000433602		1.26	[1.17-1.35]	Illumina [310881]	N
2008-12-09	18978790	McKay JD	2008-11-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18978790	Lung cancer susceptibility locus at 5p15.33.	Lung cancer	2,971 European ancestry cases, 3,746 European ancestry controls	2,899 European ancestry cases, 5,573 European ancestry controls	5p15.33	5	1320607	TERT, CLPTM1L	CLPTM1L			ENSG00000049656	NA	NA	rs402710-C	rs402710	0	402710	non_coding_transcript_exon_variant	0	NR	4e-06	5.39794000867204		1.18	[1.12-1.24]	Illumina [315194]	N
2008-12-09	18978790	McKay JD	2008-11-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18978790	Lung cancer susceptibility locus at 5p15.33.	Lung cancer	2,971 European ancestry cases, 3,746 European ancestry controls	2,899 European ancestry cases, 5,573 European ancestry controls	15q25.1	15	78601997	intergenic	CHRNA3			ENSG00000080644	NA	NA	rs1051730-A	rs1051730	0	1051730	synonymous_variant	0	NR	1e-15	15		1.35	[1.25-1.45]	Illumina [315194]	N
2010-09-07	20661308	Kapur K	2010-07-22	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20661308	Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene.	Calcium levels	8,918 European ancestry individuals, 3,947 Indian Asian ancestry individuals	4,126 European ancestry individuals	3q21.1	3	122284910	CASR	CASR			ENSG00000036828	NA	NA	rs1801725-T	rs1801725	0	1801725	missense_variant	0	0.1775	6e-37	36.2218487496164		0	[0.0031-0.0042] log(CASR, mmol/L) increase	Affymetrix, Illumina, Perlegen [2557252] (imputed)	N
2010-03-06	20150558	He M	2010-02-11	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20150558	Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.	Interleukin-18 levels	1,523 European ancestry female individuals	435 European ancestry female individuals	11q23.1	11	112180446	BCO2	AP002884.2, BCO2			ENSG00000255292, ENSG00000197580	NA	NA	rs2115763-T	rs2115763	0	2115763	intron_variant	0	0.33	4e-09	8.39794000867204		NA		Affymetrix [704409]	N
2010-03-06	20150558	He M	2010-02-11	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20150558	Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.	Interleukin-18 levels	1,523 European ancestry female individuals	435 European ancestry female individuals	11q23.1	11	112153104	BCO2	AP002884.2, IL18			ENSG00000255292, ENSG00000150782	NA	NA	rs1834481-G	rs1834481	0	1834481	non_coding_transcript_exon_variant	0	0.24	1e-08	8		NA		Affymetrix [704409]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	1q42.2	1	230539080	LOC729257	AL133516.1 - LINC01737	ENSG00000282564	ENSG00000232964		102258	53580	rs701157-C	rs701157	0	701157	intergenic_variant	1	0.45	4e-06	5.39794000867204		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	13q12.2	13	27855601	GSX1, PDX1	PLUT			ENSG00000247381	NA	NA	rs9512900-C	rs9512900	0	9512900	intron_variant	0	0.37	9e-06	5.04575749056067		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	18q21.31	18	57766970	ATP8B1	ATP8B1			ENSG00000081923	NA	NA	rs7236632-A	rs7236632	0	7236632	intron_variant	0	0.86	6e-06	5.22184874961636		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	16q22.2	16	71931293	PKD1L3, KIAA0174, DHODH	PKD1L3			ENSG00000277481	NA	NA	rs16973500-C	rs16973500	0	16973500	intron_variant	0	0.86	7e-06	5.15490195998574		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	1p35.2	1	30154865	intergenic	AL137076.1 - AL021921.1	ENSG00000233372	ENSG00000231251		13258	71658	rs2180233-C	rs2180233	0	2180233	intergenic_variant	1	0.31	9e-06	5.04575749056067		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	2p22.3	2	34255008	intergenic	LINC01320			ENSG00000228262	NA	NA	rs6733379-G	rs6733379	0	6733379	intron_variant	0	0.28	4e-06	5.39794000867204		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	1q25.3	1	183883780	GLT25D2, RGL1	RGL1			ENSG00000143344	NA	NA	rs10797919-G	rs10797919	0	10797919	splice_region_variant	0	0.59	9e-06	5.04575749056067		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	7q31.1	7	112988318	FLJ31818, GPR85	AC018464.1			ENSG00000234520	NA	NA	rs10229603-C	rs10229603	0	10229603	intron_variant	0	0.31	5e-06	5.30102999566398		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	13q33.3	13	108163877	LIG4, ABHD13	AL359436.1 - LIG4	ENSG00000286343	ENSG00000174405		230374	43562	rs10492664-C	rs10492664	0	10492664	intergenic_variant	1	0.84	1e-06	6		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	16q23.2	16	81122917	PKD1L2, C16orf46	PKD1L2			ENSG00000166473	NA	NA	rs4889240-T	rs4889240	0	4889240	intron_variant	0	0.45	7e-06	5.15490195998574		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	1q23.1	1	157160775	ETV3L, ETV3	ETV3 - AL357143.1	ENSG00000117036	ENSG00000229961		22301	10341	rs6427356-G	rs6427356	0	6427356	intergenic_variant	1	0.28	8e-06	5.09691001300806		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	2q33.1	2	202085128	FLJ39061, FZD7	KIAA2012-AS1, KIAA2012			ENSG00000222035, ENSG00000182329	NA	NA	rs1521882-A	rs1521882	0	1521882	intron_variant	0	0.82	8e-06	5.09691001300806		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	5q31.1	5	133867905	C5orf15	AC005178.1 - WSPAR	ENSG00000251243	ENSG00000249073		146971	45772	rs1644305-A	rs1644305	0	1644305	intergenic_variant	1	0.41	8e-06	5.09691001300806		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	10p15.2	10	3241815	PITRM1	LINC02668			ENSG00000226762	NA	NA	rs2764980-A	rs2764980	0	2764980	intron_variant	0	0.51	9e-06	5.04575749056067		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	14q12	14	26790837	intergenic	LINC02588, LINC02294, AL110292.1			ENSG00000257842, ENSG00000257845, ENSG00000258081	NA	NA	rs1951082-T	rs1951082	0	1951082	intron_variant	0	0.43	5e-06	5.30102999566398		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	16p13.3	16	6860384	A2BP1	RBFOX1			ENSG00000078328	NA	NA	rs12921846-A	rs12921846	0	12921846	intron_variant	0	0.40	9e-06	5.04575749056067		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	16q21	16	63921543	intergenic	LINC02165 - AC092337.1	ENSG00000261014	ENSG00000261653		165659	14235	rs1381102-A	rs1381102	0	1381102	intergenic_variant	1	0.40	6e-06	5.22184874961636		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	2p12	2	77848118	intergenic	AC012494.1			ENSG00000227088	NA	NA	rs7595103-A	rs7595103	0	7595103	intron_variant	0	0.64	7e-06	5.15490195998574		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	9p24.1	9	8235633	PTPRD	AL135923.2 - PTPRD	ENSG00000231902	ENSG00000153707		274409	78613	rs10815798-A	rs10815798	0	10815798	intergenic_variant	1	0.48	6e-06	5.22184874961636		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	11q21	11	94934799	AMOTL1, CWC15, JMJD2D	AP002383.2 - CWC15	ENSG00000256469	ENSG00000150316		9278	27821	rs10831284-G	rs10831284	0	10831284	regulatory_region_variant	1	0.13	2e-06	5.69897000433602		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	12q15	12	69938047	C12orf28	MYRFL, AC025159.1			ENSG00000166268, ENSG00000257815	NA	NA	rs789560-G	rs789560	0	789560	intron_variant	0	0.87	7e-06	5.15490195998574		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	11q24.2	11	126749295	KIRREL3	KIRREL3			ENSG00000149571	NA	NA	rs1557488-T	rs1557488	0	1557488	intron_variant	0	0.18	5e-06	5.30102999566398		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	15q26.2	15	96719197	SPATA8	AC110588.1 - FAM149B1P1	ENSG00000259340	ENSG00000214424		167680	37790	rs4533251-T	rs4533251	0	4533251	intergenic_variant	1	0.15	4e-06	5.39794000867204		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	12q21.2	12	79668450	PAWR	PAWR			ENSG00000177425	NA	NA	rs7297018-A	rs7297018	0	7297018	intron_variant	0	0.19	4e-06	5.39794000867204		NA		Perlegen [378332]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	8q22.3	8	100907093	YWHAZ	Metazoa_SRP - AC027373.1	ENSG00000278569	ENSG00000260368		8957	6154	rs931812-C	rs931812	0	931812	intergenic_variant	1	0.74	5e-06	5.30102999566398		NA		Perlegen [378332]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	6q23.3	6	137874586	TNFAIP3	TNFAIP3			ENSG00000118503	NA	NA	rs5029939-?	rs5029939	0	5029939	intron_variant	0	0.03	3e-12	11.5228787452803		2.28	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	10q11.23	10	48728291	c10orf64	WDFY4			ENSG00000128815	NA	NA	rs11101442-?	rs11101442	0	11101442	intron_variant	0	0.32	3e-06	5.52287874528034		NA	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	2p16.3	2	49728359	intergenic	AC009971.1 - RPL7P13	ENSG00000282828	ENSG00000234253		133233	150264	rs17039212-?	rs17039212	0	17039212	intergenic_variant	1	0.10	9e-06	5.04575749056067		NA	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	17p12	17	13830489	intergenic	COX10-AS1			ENSG00000236088	NA	NA	rs12949531-?	rs12949531	0	12949531	intron_variant	0	0.22	8e-06	5.09691001300806		NA	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	16p11.2	16	31322915	ITGAM	ITGAM			ENSG00000169896	NA	NA	rs11150610-?	rs11150610	0	11150610	intron_variant	0	0.42	2e-06	5.69897000433602		NA	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	8p23.1	8	11495032	BLK	BLK			ENSG00000136573	NA	NA	rs2618476-?	rs2618476	0	2618476	intron_variant	0	0.26	2e-08	7.69897000433602		1.29	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	4q28.3	4	137771096	intergenic	AC131956.3 - AC131956.1	ENSG00000287441	ENSG00000250034		15796	36610	rs2313132-?	rs2313132	0	2313132	intergenic_variant	1	0.12	8e-06	5.09691001300806		NA	[NR]	Affymetrix [313238]	N
2008-08-27	19165918	Graham RR	2008-08-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19165918	Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.	Systemic lupus erythematosus	431 European ancestry cases, 2,155 European ancestry controls	447 European ancestry trios, 293 trios	2q32.2	2	191038032	STAT4	STAT4			ENSG00000138378	NA	NA	rs3821236-?	rs3821236	0	3821236	intron_variant	0	0.19	8e-11	10.0969100130081		1.49	[NR]	Affymetrix [313238]	N
2008-12-09	18951430	Anney RJ	2008-10-24	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18951430	Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.	Attention deficit hyperactivity disorder and conduct disorder	938 European ancestry trios	NA	21q21.1	21	20512990	intergenic	RPS3AP1 - AP001506.1	ENSG00000233206	ENSG00000276738		82228	84963	rs2826340-T	rs2826340	0	2826340	intergenic_variant	1	0.17	2e-06	5.69897000433602		NA		Perlegen [378332]	N
2008-12-09	18957941	Terracciano A	2008-11-24	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/18957941	Genome-wide association scan for five major dimensions of personality.	Personality dimensions	3,972 Sardinian individuals	3,903 individuals	19q13.31	19	44466713	ZNF180	ZNF229 - ZNF285B	ENSG00000278318	ENSG00000176761		18135	928	rs644148-G	rs644148	0	644148	intergenic_variant	1	0.50	9e-07	6.04575749056067	(openness)	0.15	[NR] s.d. increase	Affymetrix [362129]	N
2008-12-09	18957941	Terracciano A	2008-11-24	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/18957941	Genome-wide association scan for five major dimensions of personality.	Personality dimensions	3,972 Sardinian individuals	3,903 individuals	4q12	4	55432027	CLOCK	CLOCK, TMEM165			ENSG00000134852, ENSG00000134851	NA	NA	rs6832769-A	rs6832769	0	6832769	3_prime_UTR_variant	0	0.73	2e-06	5.69897000433602	(agreeableness)	0.14	[NR] s.d. decrease	Affymetrix [362129]	N
2008-12-09	18957941	Terracciano A	2008-11-24	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/18957941	Genome-wide association scan for five major dimensions of personality.	Personality dimensions	3,972 Sardinian individuals	3,903 individuals	2p22.1	2	39731920	THUMPD2	TMEM178A - THUMPD2	ENSG00000152154	ENSG00000138050		13957	4140	rs2540226-T	rs2540226	0	2540226	intergenic_variant	1	0.53	3e-06	5.52287874528034	(agreeableness)	0.13	[NR] s.d. increase	Affymetrix [362129]	N
2008-12-09	18957941	Terracciano A	2008-11-24	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/18957941	Genome-wide association scan for five major dimensions of personality.	Personality dimensions	3,972 Sardinian individuals	3,903 individuals	19q13.31	19	44466713	ZNF180	ZNF229 - ZNF285B	ENSG00000278318	ENSG00000176761		18135	928	rs644148-G	rs644148	0	644148	intergenic_variant	1	0.50	8e-06	5.09691001300806	(extraversion)	0.14	[NR] s.d. increase	Affymetrix [362129]	N
2008-12-09	18957941	Terracciano A	2008-11-24	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/18957941	Genome-wide association scan for five major dimensions of personality.	Personality dimensions	3,972 Sardinian individuals	3,903 individuals	Xp11.3	X	44540940	FUNDC1	FUNDC1			ENSG00000069509	NA	NA	rs6610953-G	rs6610953	0	6610953	intron_variant	0	0.85	6e-06	5.22184874961636	(openness)	0.15	[NR] s.d. increase	Affymetrix [362129]	N
2012-02-09	22247754	Murray SS	2012-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22247754	Genome-wide association of implantable cardioverter-defibrillator activation with life-threatening arrhythmias.	Life threatening arrhythmia	607 European ancestry cases, 297 European ancestry controls	NA	15q13.1	15	29439240	KIAA0574	FAM189A1			ENSG00000273564	NA	NA	rs11856574-G	rs11856574	0	11856574	intron_variant	0	0.86	5e-06	5.30102999566398		2.02		Illumina [NR] (imputed)	N
2012-02-09	22247754	Murray SS	2012-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22247754	Genome-wide association of implantable cardioverter-defibrillator activation with life-threatening arrhythmias.	Life threatening arrhythmia	607 European ancestry cases, 297 European ancestry controls	NA	1q42.3	1	234680808	IRF2BP2	AL160408.1, AL160408.3			ENSG00000228044, ENSG00000230628	NA	NA	rs482329-C	rs482329	0	482329	splice_region_variant	0	0.61	6e-06	5.22184874961636		1.6		Illumina [NR] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	11q14.1	11	79372576	NR	TENM4			ENSG00000149256	NA	NA	rs12290811-A	rs12290811	0	12290811	intron_variant	0	0.15	4e-06	5.39794000867204		1.2	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	10q21.2	10	60420054	ANK3	ANK3			ENSG00000151150	NA	NA	rs10994336-T	rs10994336	0	10994336	intron_variant	0	0.05	9e-09	8.04575749056067		1.45	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	2q11.2	2	96747751	intergenic	LMAN2L - CNNM4	ENSG00000114988	ENSG00000158158		7687	13151	rs2314398-?	rs2314398	0	2314398	regulatory_region_variant	1	0.69	3e-06	5.52287874528034		1.17	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	3p24.3	3	21207150	NR	AC099753.1			ENSG00000282987	NA	NA	rs11720452-?	rs11720452	0	11720452	intron_variant	0	0.58	5e-06	5.30102999566398		1.15	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	15q14	15	38703290	C15orf53, RASGRP1	LINC02694			ENSG00000175779	NA	NA	rs12899449-?	rs12899449	0	12899449	intron_variant	0	0.72	4e-07	6.39794000867204		1.2	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	14q13.1	14	33011716	NR	NPAS3			ENSG00000151322	NA	NA	rs8015959-T	rs8015959	0	8015959	intron_variant	0	0.02	5e-06	5.30102999566398		1.59	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	3p26.2	3	3617156	NR	AC034195.1			ENSG00000223727	NA	NA	rs1601875-?	rs1601875	0	1601875	intron_variant	0	0.50	7e-06	5.15490195998574		1.14	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	9q33.3	9	127345685	NR	GARNL3			ENSG00000136895	NA	NA	rs4130590-?	rs4130590	0	4130590	intron_variant	0	0.56	3e-06	5.52287874528034		1.16	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	15q14	15	38219782	NR	AC087473.1			ENSG00000259380	NA	NA	rs16966460-G	rs16966460	0	16966460	intron_variant	0	0.10	4e-06	5.39794000867204		1.26	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	14q11.2	14	23912306	NR	AL136419.2 - LINC00596	ENSG00000285727	ENSG00000259334		29878	9941	rs12436436-C	rs12436436	0	12436436	intergenic_variant	1	0.08	5e-06	5.30102999566398		1.3	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	3p22.3	3	32288005	NR	CMTM8			ENSG00000170293	NA	NA	rs4380451-?	rs4380451	0	4380451	intron_variant	0	0.73	4e-06	5.39794000867204		1.18	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	9p13.3	9	33799372	NR	UBE2R2-AS1			ENSG00000235481	NA	NA	rs216345-T	rs216345	0	216345	intron_variant	0	0.37	4e-06	5.39794000867204		1.15	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	3p24.3	3	21664877	NR	ZNF385D			ENSG00000151789	NA	NA	rs3821396-A	rs3821396	0	3821396	intron_variant	0	0.11	5e-06	5.30102999566398		1.23	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	1p21.2	1	101472921	NR	LINC01307 - LINC01709	ENSG00000231671	ENSG00000226715		82618	166588	rs1948368-?	rs1948368	0	1948368	intergenic_variant	1	0.51	6e-06	5.22184874961636		1.15	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	11q24.2	11	124668099	NR	SIAE			ENSG00000110013	NA	NA	rs544368-T	rs544368	0	544368	intron_variant	0	0.12	6e-06	5.22184874961636		1.22	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	15q25.1	15	80402580	NR	AC016705.2			ENSG00000259495	NA	NA	rs2278702-?	rs2278702	0	2278702	intron_variant	0	0.83	6e-06	5.22184874961636		1.21	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	18p11.32	18	278796	NR	AP000845.1 - COLEC12	ENSG00000263884	ENSG00000158270		8518	37941	rs7226677-G	rs7226677	0	7226677	intergenic_variant	1	0.12	7e-06	5.15490195998574		1.24	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	10q22.3	10	79195310	NR	ZMIZ1			ENSG00000108175	NA	NA	rs703965-?	rs703965	0	703965	intron_variant	0	0.54	8e-06	5.09691001300806		1.15	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	12p13.33	12	2236129	CACNA1C	CACNA1C, CACNA1C			ENSG00000151067, ENSG00000285479	NA	NA	rs1006737-A	rs1006737	0	1006737	intron_variant	0	0.32	7e-08	7.15490195998574		1.18	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	6q25.2	6	152417619	NR	SYNE1			ENSG00000131018	NA	NA	rs17082664-G	rs17082664	0	17082664	intron_variant	0	0.13	4e-06	5.39794000867204		1.22	[NR]	Affymetrix [1769948] (imputed)	N
2008-09-12	18711365	Ferreira MA	2008-08-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18711365	Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.	Bipolar disorder	4,387 European ancestry cases, 6,209 European ancestry controls	NA	9q31.3	9	110434983	NR	SVEP1			ENSG00000165124	NA	NA	rs7042161-?	rs7042161	0	7042161	intron_variant	0	0.65	6e-06	5.22184874961636		1.15	[NR]	Affymetrix [1769948] (imputed)	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	14q24.3	14	76346148	intergenic	ESRRB			ENSG00000119715	NA	NA	rs2360997-C	rs2360997	0	2360997	intron_variant	0	0.86	8e-06	5.09691001300806	(maternal warmth)	1.3	[NR] unit decrease	Perlegen [429981]	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	11q21	11	94579157	PIWIL4	AP000943.2, PIWIL4			ENSG00000255929, ENSG00000134627	NA	NA	rs2212361-C	rs2212361	0	2212361	intron_variant	0	0.26	9e-07	6.04575749056067	(maternal warmth)	0.97	[NR] unit decrease	Perlegen [429981]	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	8p23.2	8	5604231	intergenic	AC004944.1 - AC084768.1	ENSG00000253510	ENSG00000254007		95105	55448	rs4875598-G	rs4875598	0	4875598	regulatory_region_variant	1	0.34	9e-06	5.04575749056067	(maternal warmth)	0.94	[NR] unit decrease	Perlegen [429981]	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	13q12.3	13	28857201	intergenic	MTUS2			ENSG00000132938	NA	NA	rs1161463-C	rs1161463	0	1161463	intron_variant	0	0.79	2e-06	5.69897000433602	(maternal warmth)	1.72	[NR] unit decrease	Perlegen [429981]	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	6p21.2	6	39571431	KIF6	KIF6			ENSG00000164627	NA	NA	rs4714261-T	rs4714261	0	4714261	intron_variant	0	0.17	2e-06	5.69897000433602	(maternal warmth)	0.95	[NR] unit increase	Perlegen [429981]	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	21q21.1	21	19164331	intergenic	AP000431.1 - SLC6A6P1	ENSG00000229289	ENSG00000226818		29908	80212	rs2825388-A	rs2825388	0	2825388	intergenic_variant	1	0.4	8e-06	5.09691001300806	(maternal criticism)	1.06	[NR] unit increase	Perlegen [429981]	N
2008-12-09	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Attention deficit hyperactivity disorder symptoms (maternal expressed emotions interaction)	909 European ancestry trios	NA	3q27.2	3	185968952	intergenic	NMRAL2P			ENSG00000171658	NA	NA	rs10049246-G	rs10049246	0	10049246	intron_variant	0	0.59	8e-06	5.09691001300806	(maternal warmth)	0.6	[NR] unit increase	Perlegen [429981]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	4q22.1	4	88282518	PPM1K	PPM1K			ENSG00000163644	NA	NA	rs893971-T	rs893971	0	893971	intron_variant	0	0.6	7e-06	5.15490195998574	(maternal warmth)	1.15	[NR] unit decrease	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	15q26.2	15	95613139	intergenic	LINC00924 - AC015574.1	ENSG00000259134	ENSG00000275016		105274	25177	rs4321143-G	rs4321143	0	4321143	intergenic_variant	1	0.28	7e-06	5.15490195998574	(maternal criticism)	1.13	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	2p22.2	2	37749874	intergenic	AC006369.2 - AC010878.1	ENSG00000236572	ENSG00000225402		2828	67041	rs604381-A	rs604381	0	604381	regulatory_region_variant	1	0.32	8e-06	5.09691001300806	(maternal warmth)	1.26	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	17q22	17	53160580	intergenic	MTCO1P40 - AC034268.2	ENSG00000262902	ENSG00000285939		54222	116180	rs8073783-C	rs8073783	0	8073783	intergenic_variant	1	0.49	8e-06	5.09691001300806	(maternal warmth)	1.76	[NR] unit decrease	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	8p23.1	8	8859497	MFHAS1	MFHAS1, MFHAS1			ENSG00000285022, ENSG00000147324	NA	NA	rs332034-A	rs332034	0	332034	intron_variant	0	0.85	6e-06	5.22184874961636	(maternal warmth)	1.05	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	5q21.1	5	101612841	intergenic	RN7SL802P - OR7H2P	ENSG00000277506	ENSG00000251261		30713	203634	rs13188771-A	rs13188771	0	13188771	intergenic_variant	1	0.17	2e-06	5.69897000433602	(maternal warmth)	4.24	[NR] unit decrease	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	2p21	2	41777857	intergenic	AC009413.2 - LDHAP3	ENSG00000287145	ENSG00000236090		46246	41890	rs719593-T	rs719593	0	719593	intergenic_variant	1	0.86	5e-06	5.30102999566398	(maternal criticism)	2.05	[NR] unit decrease	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	6q15	6	88266258	intergenic	AL139042.1			ENSG00000234426	NA	NA	rs16880441-G	rs16880441	0	16880441	intron_variant	0	0.08	9e-06	5.04575749056067	(maternal criticism)	1.63	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	11q23.2	11	114091040	ZBTB16	ZBTB16			ENSG00000109906	NA	NA	rs17116334-T	rs17116334	0	17116334	intron_variant	0	0.16	9e-06	5.04575749056067	(maternal criticism)	1.3	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	3p25.3	3	10998753	SLC6A1	SLC6A1			ENSG00000157103	NA	NA	rs9990174-T	rs9990174	0	9990174	intron_variant	0	0.33	6e-06	5.22184874961636	(maternal warmth)	2.52	[NR] unit decrease	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	10q22.3	10	78341104	intergenic	LINC00595, AC012560.1			ENSG00000230417, ENSG00000282863	NA	NA	rs2395528-T	rs2395528	0	2395528	intron_variant	0	0.23	6e-06	5.22184874961636	(maternal warmth)	1.46	[NR] unit decrease	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	1q22	1	155898834	RIT1	RIT1			ENSG00000143622	NA	NA	rs2282301-A	rs2282301	0	2282301	3_prime_UTR_variant	0	0.23	7e-06	5.15490195998574	(maternal warmth)	2.88	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	18q12.3	18	43228833	intergenic	AC100779.1 - SYT4	ENSG00000287209	ENSG00000132872		99794	39059	rs17664267-T	rs17664267	0	17664267	intergenic_variant	1	0.19	7e-06	5.15490195998574	(maternal warmth)	1.39	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	4q23	4	99329262	ADH1C	ADH1B			ENSG00000196616	NA	NA	rs1789891-A	rs1789891	0	1789891	intron_variant	0	0.14	3e-06	5.52287874528034	(maternal warmth)	1.47	[NR] unit increase	Perlegen [429901]	N
2009-01-15	18846501	Sonuga-Barke EJ	2008-10-07	Am J Med Genet B Neuropsychiatr Genet	www.ncbi.nlm.nih.gov/pubmed/18846501	Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.	Conduct disorder (maternal expressed emotions interaction)	909 European ancestry trios	NA	16p13.3	16	6063660	A2BP1	AC009135.1, RBFOX1			ENSG00000257180, ENSG00000078328	NA	NA	rs6500744-C	rs6500744	0	6500744	intron_variant	0	0.53	3e-06	5.52287874528034	(maternal warmth)	0.91	[NR] unit increase	Perlegen [429901]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	14q32.12	14	92307319	SLC24A4	AL133240.2 - SLC24A4	ENSG00000286630	ENSG00000140090		9671	15262	rs12896399-G	rs12896399	0	12896399	intergenic_variant	1	NR	8e-21	20.0969100130081		0.18	[0.14-0.22] hair color score increase	Illumina [528173]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	15q13.1	15	28090674	OCA2	OCA2, OCA2			ENSG00000277361, ENSG00000104044	NA	NA	rs11855019-G	rs11855019	1	4778138	intron_variant	0	NR	2e-24	23.698970004336		0.28	[0.22-0.34] hair color score decrease	Illumina [528173]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	15q13.1	15	28760947	intergenic	WHAMMP2 - AC055876.4	ENSG00000248334	ENSG00000260844		1743	2493	rs8033165-T	rs8033165	0	8033165	intergenic_variant	1	NR	5e-11	10.301029995664		0.12	[0.08-0.16] hair color score increase	Illumina [528173]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	15q13.1	15	28120472	HERC2	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs12913832-A	rs12913832	0	12913832	intron_variant	0	NR	4e-103	102.397940008672		0.44	[0.40-0.48] hair color score decrease	Illumina [528173]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	6p25.3	6	396321	IRF4	IRF4			ENSG00000137265	NA	NA	rs12203592-T	rs12203592	0	12203592	intron_variant	0	NR	7e-127	126.154901959986		0.35	[0.33-0.37] hair color score decrease	Illumina [528173]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	5p13.2	5	33958854	MATP	SLC45A2, SLC45A2			ENSG00000164175, ENSG00000281919	NA	NA	rs28777-C	rs28777	0	28777	intron_variant	0	NR	1e-17	17		0.46	[0.36-0.56] hair color score decrease	Illumina [528173]	N
2008-06-20	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. blond hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	6p25.3	6	542159	EXOC2	EXOC2			ENSG00000112685	NA	NA	rs6918152-A	rs6918152	0	6918152	intron_variant	0	NR	6e-08	7.22184874961636		0.11	[0.07-0.15] hair color score increase	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	15q13.1	15	28120472	HERC2	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs12913832-A	rs12913832	0	12913832	intron_variant	0	NR	1e-77	77		0.44	[0.40-0.48] hair color score decrease	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	15q13.1	15	28760947	intergenic	WHAMMP2 - AC055876.4	ENSG00000248334	ENSG00000260844		1743	2493	rs8033165-T	rs8033165	0	8033165	intergenic_variant	1	NR	2e-12	11.698970004336		0.15	[0.11-0.19] hair color score increase	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	6p25.3	6	542159	EXOC2	EXOC2			ENSG00000112685	NA	NA	rs6918152-A	rs6918152	0	6918152	intron_variant	0	NR	5e-07	6.30102999566398		0.11	[0.07-0.15] hair color score increase	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	16q24.3	16	89689495	MC1R	CDK10			ENSG00000185324	NA	NA	rs258322-T	rs258322	0	258322	intron_variant	0	NR	2e-23	22.698970004336		0.36	[0.28-0.44] hair color score increase	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	5p13.2	5	33958854	MATP	SLC45A2, SLC45A2			ENSG00000164175, ENSG00000281919	NA	NA	rs28777-C	rs28777	0	28777	intron_variant	0	NR	9e-14	13.0457574905607		0.46	[0.34-0.58] hair color score decrease	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	6p25.3	6	396321	IRF4	IRF4			ENSG00000137265	NA	NA	rs12203592-T	rs12203592	0	12203592	intron_variant	0	NR	9e-28	27.0457574905607		0.31	[0.25-0.36] hair color score decrease	Illumina [528173]	N
2008-07-01	18483556	Han J	2008-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/18483556	A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.	Black vs. red hair color	2,287 European ancestry female individuals	8,465 European ancestry individuals	15q13.1	15	28090674	OCA2	OCA2, OCA2			ENSG00000277361, ENSG00000104044	NA	NA	rs11855019-G	rs11855019	1	4778138	intron_variant	0	NR	6e-20	19.2218487496164		0.29	[0.23-0.35] hair color score decrease	Illumina [528173]	N
2010-09-23	20719862	Vitart V	2010-08-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20719862	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	Central corneal thickness	1,445 European ancestry individuals	5,882 European ancestry individuals	15q25.3	15	85282336	PDE8A, AKAP13	ADAMTS7P4			ENSG00000218052	NA	NA	rs6496932-C	rs6496932	0	6496932	intron_variant	0	0.22	1e-08	8		0.13	[0.09-0.18] unit increase	Illumina [~ 2000000] (imputed)	N
2010-09-23	20719862	Vitart V	2010-08-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20719862	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	Central corneal thickness	1,445 European ancestry individuals	5,882 European ancestry individuals	13q14.11	13	40535292	FOXO1	LINC00598, FOXO1			ENSG00000215483, ENSG00000150907	NA	NA	rs2755237-A	rs2755237	0	2755237	intron_variant	0	NR	1e-08	8		0.17	[0.11-0.23] unit increase	Illumina [~ 2000000] (imputed)	N
2010-09-23	20719862	Vitart V	2010-08-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20719862	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	Central corneal thickness	1,445 European ancestry individuals	5,882 European ancestry individuals	9q34.3	9	134676205	COL5A1	COL5A1			ENSG00000130635	NA	NA	rs7044529-A	rs7044529	0	7044529	intron_variant	0	NR	5e-08	7.30102999566398		0.13	[0.09-0.18] unit decrease	Illumina [~ 2000000] (imputed)	N
2010-09-23	20719862	Vitart V	2010-08-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20719862	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	Central corneal thickness	1,445 European ancestry individuals	5,882 European ancestry individuals	13q12.12	13	22654552	AVGR8, AL354828.1	AL512484.1 - FTH1P7	ENSG00000287357	ENSG00000232187		60681	41471	rs1034200-C	rs1034200	0	1034200	intergenic_variant	1	0.22	4e-09	8.39794000867204		0.14	[0.10-0.19] unit decrease	Illumina [~ 2000000] (imputed)	N
2010-09-23	20719862	Vitart V	2010-08-18	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20719862	New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.	Central corneal thickness	1,445 European ancestry individuals	5,882 European ancestry individuals	16q24.2	16	88264518	BANP, ZNF469	AC138512.1			ENSG00000261273	NA	NA	rs12447690-G	rs12447690	0	12447690	intron_variant	0	0.38	6e-22	21.2218487496164		0.16	[0.13-0.19] unit decrease	Illumina [~ 2000000] (imputed)	N
2008-06-27	18364390	Capon F	2008-03-25	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/18364390	Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.	Psoriasis	318 European ancestry cases, 288 European ancestry controls	2,361 European ancestry cases, 1,927 European ancestry controls	20q13.13	20	49905793	SPATA2	SPATA2			ENSG00000158480	NA	NA	rs495337-?	rs495337	0	495337	synonymous_variant	0	NR	1e-08	8		1.25	[1.12-1.39]	Illumina [~ 408000]	N
2008-06-27	18364390	Capon F	2008-03-25	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/18364390	Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.	Psoriasis	318 European ancestry cases, 288 European ancestry controls	2,361 European ancestry cases, 1,927 European ancestry controls	6p21.33	6	31344549	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs3134792-?	rs3134792	0	3134792	intron_variant	0	NR	1e-09	9		NA		Illumina [~ 408000]	N
2013-04-18	23349225	Hwang JY	2013-01-24	J Med Genet	www.ncbi.nlm.nih.gov/pubmed/23349225	Meta-analysis identifies a MECOM gene as a novel predisposing factor of osteoporotic fracture.	Osteoporosis	288 Korean ancestry cases, 1,139 Korean ancestry controls	831 East Asian ancestry cases, 2305 East Asian ancestry controls	3q26.2	3	169253443	MECOM	MECOM			ENSG00000085276	NA	NA	rs784288-A	rs784288	0	784288	intron_variant	0	0.23	4e-08	7.39794000867204		1.39	[1.24-1.56]	Affymetrix [1573409] (imputed)	N
2010-09-22	20711176	Nakashima M	2010-08-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20711176	A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.	Keloid	178 Japanese ancestry cases, 906 Japanese ancestry controls	621 Japanese ancestry cases, 2,271 Japanese ancestry controls	15q21.3	15	55902679	NEDD4	NEDD4			ENSG00000069869	NA	NA	rs8032158-C	rs8032158	0	8032158	intron_variant	0	0.36	6e-13	12.2218487496164		1.51	[1.35-1.69]	Illumina [452038]	N
2010-09-22	20711176	Nakashima M	2010-08-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20711176	A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.	Keloid	178 Japanese ancestry cases, 906 Japanese ancestry controls	621 Japanese ancestry cases, 2,271 Japanese ancestry controls	3p21.31	3	50314769	NR	HYAL1 - HYAL2	ENSG00000114378	ENSG00000068001		2388	3021	rs11130248-?	rs11130248	0	11130248	regulatory_region_variant	1	0.52	5e-07	6.30102999566398		1.34	[1.19-1.49]	Illumina [452038]	N
2010-09-22	20711176	Nakashima M	2010-08-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20711176	A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.	Keloid	178 Japanese ancestry cases, 906 Japanese ancestry controls	621 Japanese ancestry cases, 2,271 Japanese ancestry controls	3q22.3	3	138994862	FOXL2, LOC389151	FOXL2NB - PRR23A	ENSG00000206262	ENSG00000206260		40872	9100	rs1511412-A	rs1511412	0	1511412	regulatory_region_variant	1	0.08	2e-13	12.698970004336		1.87	[1.58-2.21]	Illumina [452038]	N
2010-09-22	20711176	Nakashima M	2010-08-15	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20711176	A genome-wide association study identifies four susceptibility loci for keloid in the Japanese population.	Keloid	178 Japanese ancestry cases, 906 Japanese ancestry controls	621 Japanese ancestry cases, 2,271 Japanese ancestry controls	1q41	1	222098425	intergenic	AL356108.1			ENSG00000236230	NA	NA	rs873549-C	rs873549	0	873549	intron_variant	0	0.28	6e-23	22.2218487496164		1.77	[1.58-1.99]	Illumina [452038]	N
2012-07-24	22673963	Lasky-Su J	2012-06-07	Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22673963	Genome-wide association analysis of circulating vitamin D levels in children with asthma.	Vitamin D levels	422 European ancestry trios with asthmatic children, 150 European ancestry asthmatic child cases	1,108 Hispanic asthmatic child cases	4q13.3	4	71742666	GC	GC			ENSG00000145321	NA	NA	rs2282679-?	rs2282679	0	2282679	intron_variant	0	0.29	2e-14	13.698970004336		NA		Illumina [547645]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (hip)	5,861 European ancestry individuals	7,925 European ancestry individuals	13q14.11	13	42378009	RANKL	LINC02341			ENSG00000283554	NA	NA	rs9594738-T	rs9594738	0	9594738	intron_variant	0	0.56	2e-08	7.69897000433602		0.1	[0.06-0.13] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (hip)	5,861 European ancestry individuals	7,925 European ancestry individuals	18q21.33	18	62414860	RANK	TNFRSF11A - RPL17P44	ENSG00000141655	ENSG00000241088		23572	818	rs3018362-A	rs3018362	0	3018362	intergenic_variant	1	0.35	1e-06	6		0.07	[0.04-0.10] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (hip)	5,861 European ancestry individuals	7,925 European ancestry individuals	1p36.12	1	22371954	ZBTB40	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		5472	56884	rs7524102-A	rs7524102	0	7524102	intergenic_variant	1	0.82	5e-16	15.301029995664		0.15	[0.11-0.19] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (hip)	5,861 European ancestry individuals	7,925 European ancestry individuals	8q24.12	8	119039999	OPG	COLEC10			ENSG00000184374	NA	NA	rs6993813-C	rs6993813	0	6993813	intron_variant	0	0.50	3e-11	10.5228787452803		0.09	[0.07-0.12] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (hip)	5,861 European ancestry individuals	7,925 European ancestry individuals	6q25.1	6	151580274	ESR1, C6orf97	CCDC170			ENSG00000120262	NA	NA	rs4870044-T	rs4870044	0	4870044	intron_variant	0	0.28	2e-07	6.69897000433602		0.08	[0.05-0.11] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (hip)	5,861 European ancestry individuals	7,925 European ancestry individuals	6q25.1	6	151612040	ESR1	CCDC170			ENSG00000120262	NA	NA	rs1038304-G	rs1038304	0	1038304	intron_variant	0	0.47	5e-09	8.30102999566398		0.08	[0.06-0.11] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	1p36.12	1	22371954	ZBTB40	AL591122.1 - ZBTB40	ENSG00000279625	ENSG00000184677		5472	56884	rs7524102-A	rs7524102	0	7524102	intergenic_variant	1	0.82	9e-09	8.04575749056067		0.11	[0.07-0.15] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	6q25.1	6	151580274	ESR1	CCDC170			ENSG00000120262	NA	NA	rs4870044-T	rs4870044	0	4870044	intron_variant	0	0.28	2e-11	10.698970004336		0.11	[0.08-0.14] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	2p16.2	2	54457420	SPTBN1	SPTBN1			ENSG00000115306	NA	NA	rs11898505-G	rs11898505	0	11898505	intron_variant	0	0.67	8e-07	6.09691001300806		0.08	[0.05-0.11] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	6p21.32	6	32276850	MHC, C6orf10	TSBP1-AS1			ENSG00000225914	NA	NA	rs3130340-T	rs3130340	0	3130340	intron_variant	0	0.79	1e-07	7		0.1	[0.06-0.13] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	8q24.12	8	119032590	OPG	COLEC10			ENSG00000184374	NA	NA	rs6469804-A	rs6469804	0	6469804	intron_variant	0	0.51	7e-15	14.1549019599857		0.12	[0.09-0.15] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	13q14.11	13	42458457	RANKL	LINC02341			ENSG00000283554	NA	NA	rs9594759-T	rs9594759	0	9594759	intron_variant	0	0.62	2e-21	20.698970004336		0.17	[0.14-0.21] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	6q25.1	6	151612040	ESR1, C6orf97	CCDC170			ENSG00000120262	NA	NA	rs1038304-G	rs1038304	0	1038304	intron_variant	0	0.47	4e-11	10.397940008672		0.1	[0.07-0.13] s.d. decrease	Illumina [301019]	N
2008-06-20	18445777	Styrkarsdottir U	2008-04-29	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/18445777	Multiple genetic loci for bone mineral density and fractures.	Bone mineral density (spine)	5,861 European ancestry individuals	7,925 European ancestry individuals	6q25.1	6	151747229	ESR1, C6orf97	ESR1			ENSG00000091831	NA	NA	rs1999805-C	rs1999805	0	1999805	intron_variant	0	0.44	2e-08	7.69897000433602		0.09	[0.06-0.12] s.d. decrease	Illumina [301019]	N
2008-08-07	18723019	Franke A	2008-07-21	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/18723019	Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.	Crohn's disease and sarcoidosis (combined)	382 European ancestry Crohn's disease cases, 398 European ancestry Sarcoidosis cases, 394 European ancestry controls	660 European ancestry Crohn's disease cases, 657 European ancestry Sarcoidosis cases, 1,091 European ancestry controls	10p12.2	10	23376509	C10orf67	AL606469.1 - AL606469.2	ENSG00000224215	ENSG00000264574		31328	16896	rs1398024-A	rs1398024	0	1398024	intergenic_variant	1	0.25	4e-06	5.39794000867204		1.23	[1.04-1.45]	Affymetrix [83360]	N
2013-04-17	23341777	Dong J	2013-01-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23341777	Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in han chinese.	Squamous cell carcinoma	833 Han Chinese ancestry cases, 3,094 Han Chinese ancestry controls	2,223 Han Chinese ancestry cases, 6,409 Han Chinese ancestry controls	12q23.1	12	100426307	SLC17A8, NR1H4, SCYL2, GAS2L3	SLC17A8 - NR1H4	ENSG00000179520	ENSG00000012504		4252	47401	rs12296850-A	rs12296850	0	12296850	intergenic_variant	1	0.744	1e-10	10		1.28	[1.19-1.39]	Affymetrix [570009]	N
2010-06-09	20460270	Garcia-Barcelo MM	2010-05-11	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20460270	Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2.	Biliary atresia	281 Chinese ancestry cases, 481 Chinese ancestry controls	124 Chinese ancestry cases, 90 Chinese ancestry controls	10q25.1	10	109975992	XPNPEP1, ADD3	ADD3-AS1			ENSG00000203876	NA	NA	rs17095355-T	rs17095355	0	17095355	intron_variant	0	0.409	7e-09	8.15490195998574		1.77	[1.38-2.26]	Affymetrix [289118]	N
2010-06-09	20460270	Garcia-Barcelo MM	2010-05-11	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20460270	Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2.	Biliary atresia	281 Chinese ancestry cases, 481 Chinese ancestry controls	124 Chinese ancestry cases, 90 Chinese ancestry controls	12q13.13	12	53876444	HOXC13	AC076968.2			ENSG00000286069	NA	NA	rs2120991-A	rs2120991	0	2120991	intron_variant	0	0.134	9e-06	5.04575749056067		2.14	[1.58-2.89]	Affymetrix [289118]	N
2010-06-09	20460270	Garcia-Barcelo MM	2010-05-11	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/20460270	Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2.	Biliary atresia	281 Chinese ancestry cases, 481 Chinese ancestry controls	124 Chinese ancestry cases, 90 Chinese ancestry controls	13q12.3	13	29884600	UBL3	LINC00297			ENSG00000224329	NA	NA	rs9314986-G	rs9314986	0	9314986	intron_variant	0	0.044	2e-06	5.69897000433602		2.95	[1.89-4.60]	Affymetrix [289118]	N
2011-11-24	22019779	Takahashi Y	2011-10-23	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22019779	A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis.	Scoliosis	1,033 Japanese ancestry adolescent female cases, 1,473 Japanese ancestry female controls	326 Japanese ancestry adolescent female cases, 9,823 Japanese ancestry female controls	10q24.32	10	101219450	LBX1	LINC01514 - LBX1	ENSG00000237579	ENSG00000138136		25303	6745	rs11190870-?	rs11190870	0	11190870	intergenic_variant	1	0.57	1e-19	19		1.56	[1.41-1.71]	Illumina [455121]	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	1p13.3	1	109275216	CELSR2	CELSR2			ENSG00000143126	NA	NA	rs660240-T	rs660240	0	660240	3_prime_UTR_variant	0	0.22	2e-22	21.698970004336	(LDL)	0.17	[0.14-0.20] mmol/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	4q22.1	4	88124179	ABCG2	ABCG2			ENSG00000118777	NA	NA	rs2199936-A	rs2199936	0	2199936	intron_variant	0	0.12	2e-17	16.698970004336	(UA)	0.188	[0.14-0.23] umol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA				MRC1					NA	NA	rs2437258-T	rs2437258	0	2437258		1	0.23	3e-10	9.52287874528034	(AST)	0.102	[0.071-0.133] units/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	2p24.1	2	21021128	APOB	APOB			ENSG00000084674	NA	NA	rs10199768-T	rs10199768	0	10199768	intron_variant	0	0.47	8e-15	14.0969100130081	(LDL)	0.11	[0.083-0.137] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	3q26.1	3	165773492	BCHE	LINC01322, BCHE			ENSG00000244128, ENSG00000114200	NA	NA	rs1803274-T	rs1803274	0	1803274	missense_variant	0	0.21	6e-92	91.2218487496164	(BCHE)	0.365	[0.33-0.40] units/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	4p16.1	4	10054752	WDR1	SLC2A9			ENSG00000109667	NA	NA	rs7671266-T	rs7671266	0	7671266	intron_variant	0	0.21	9e-71	70.0457574905607	(UA)	0.305	[0.27-0.34] umol/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	4p16.1	4	10329670	intergenic	AC006499.7 - AC110768.2	ENSG00000251338	ENSG00000250613		34091	81326	rs4698036-G	rs4698036	0	4698036	intergenic_variant	1	0.22	2e-52	51.698970004336	(UA)	0.257	[0.22-0.29] umol/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	8p21.3	8	19992246	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		24987	86868	rs17091905-A	rs17091905	0	17091905	intergenic_variant	1	0.124	6e-12	11.2218487496164	(HDL)	0.15	[0.11-0.19] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	8p21.3	8	19992246	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		24987	86868	rs17091905-A	rs17091905	0	17091905	intergenic_variant	1	0.12	5e-15	14.301029995664	(TRIG)	0.174	[0.13-0.22] mmol/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	12q24.31	12	121033534	OASL	OASL			ENSG00000135114	NA	NA	rs3213545-A	rs3213545	0	3213545	synonymous_variant	0	0.30	4e-15	14.397940008672	(GGT)	0.121	[0.092-0.150] units/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	15q21.3	15	58386313	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs10468017-T	rs10468017	0	10468017	intron_variant	0	0.33	3e-12	11.5228787452803	(HDL)	0.104	[0.075-0.133] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	16q13	16	56954132	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		9268	7791	rs173539-T	rs173539	0	173539	intergenic_variant	1	0.32	3e-65	64.5228787452803	(HDL)	0.255	[0.23-0.28] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	19q13.32	19	44892362	TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-G	rs2075650	0	2075650	intron_variant	0	0.15	2e-14	13.698970004336	(LDL)	0.153	[0.11-0.19] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	19q13.32	19	44892362	TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-G	rs2075650	0	2075650	intron_variant	0	0.15	4e-08	7.39794000867204	(CRP)	0.116	[0.075-0.157] unit decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-T	rs1260326	0	1260326	missense_variant	0	0.40	2e-08	7.69897000433602	(TRIG)	0.082	[0.053-0.111] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	6p22.2	6	25776721	SLC17A4	SLC17A4			ENSG00000146039	NA	NA	rs11754288-A	rs11754288	0	11754288	missense_variant	0	0.43	4e-09	8.39794000867204	(UA)	0.084	[0.057-0.111] umol/l decrease	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	0.08	5e-12	11.301029995664	(FERR)	0.177	[0.13-0.23] mg/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	11q23.3	11	117204850	PCSK7	TAGLN, PCSK7			ENSG00000149591, ENSG00000160613	NA	NA	rs508487-T	rs508487	0	508487	3_prime_UTR_variant	0	0.04	2e-10	9.69897000433602	(TRIG)	0.235	[0.16-0.31] mmol/l increase	Illumina [NR] (imputed)	N
2011-10-20	21943158	Middelberg RP	2011-09-24	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/21943158	Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits.	Cardiovascular disease risk factors	11,683 European ancestry individuals	NA	19p13.2	19	11091630	LDLR	LDLR			ENSG00000130164	NA	NA	rs6511720-T	rs6511720	0	6511720	intron_variant	0	0.11	5e-11	10.301029995664	(LDL)	0.148	[0.10-0.19] mmol/l decrease	Illumina [NR] (imputed)	N
2013-01-10	23065704	Amin Al Olama A	2012-10-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23065704	A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.	Prostate cancer	5,132 European ancestry non-aggressive cases, 5,953 European ancestry aggressive cases, 11,463 European ancestry controls	22,387 European ancestry non-aggressive cases, 2,008 European ancestry aggressive cases, up to 24,726 European ancestry controls	19q13.2	19	41479679	ATP5SL, CEACAM21	PCAT19			ENSG00000267107	NA	NA	rs11672691-G	rs11672691	0	11672691	non_coding_transcript_exon_variant	0	NR	1e-08	8	(Aggressive)	1.11	[1.02-1.20]	Illumina [~ 2600000] (imputed)	N
2013-01-10	23065704	Amin Al Olama A	2012-10-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23065704	A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.	Prostate cancer	5,132 European ancestry non-aggressive cases, 5,953 European ancestry aggressive cases, 11,463 European ancestry controls	22,387 European ancestry non-aggressive cases, 2,008 European ancestry aggressive cases, up to 24,726 European ancestry controls	19q13.2	19	41479679	ATP5SL, CEACAM21	PCAT19			ENSG00000267107	NA	NA	rs11672691-G	rs11672691	0	11672691	non_coding_transcript_exon_variant	0	NR	2e-12	11.698970004336	(All)	1.08	[1.04-1.12]	Illumina [~ 2600000] (imputed)	N
2013-01-10	23065704	Amin Al Olama A	2012-10-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23065704	A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.	Prostate cancer	5,132 European ancestry non-aggressive cases, 5,953 European ancestry aggressive cases, 11,463 European ancestry controls	22,387 European ancestry non-aggressive cases, 2,008 European ancestry aggressive cases, up to 24,726 European ancestry controls	22q13.1	22	40040969	TNRC6B	FAM83F			ENSG00000133477	NA	NA	rs11704416-C	rs11704416	0	11704416	3_prime_UTR_variant	0	NR	4e-06	5.39794000867204	(Aggressive)	1.05	[0.96-1.15]	Illumina [~ 2600000] (imputed)	N
2013-01-10	23065704	Amin Al Olama A	2012-10-12	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23065704	A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.	Prostate cancer	5,132 European ancestry non-aggressive cases, 5,953 European ancestry aggressive cases, 11,463 European ancestry controls	22,387 European ancestry non-aggressive cases, 2,008 European ancestry aggressive cases, up to 24,726 European ancestry controls	22q13.1	22	40040969	TNRC6B	FAM83F			ENSG00000133477	NA	NA	rs11704416-C	rs11704416	0	11704416	3_prime_UTR_variant	0	NR	4e-07	6.39794000867204	(All)	1.06	[1.02-1.10]	Illumina [~ 2600000] (imputed)	N
2009-07-30	19597491	Gudbjartsson DF	2009-07-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19597491	A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.	Atrial fibrillation	2,385 European ancestry cases, 33,752 European ancestry controls	up to 2,427 European ancestry cases, 3,379 European ancestry controls, 286 Han Chinese ancestry cases, 2,763 Han Chinese ancestry controls	4q25	4	110789013	intergenic	PITX2 - LINC01438	ENSG00000164093	ENSG00000249519		146890	5390	rs2200733-?	rs2200733	0	2200733	intergenic_variant	1	0.12	1e-14	14		1.42	[NR]	Illumina [303136]	N
2009-07-30	19597491	Gudbjartsson DF	2009-07-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19597491	A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.	Atrial fibrillation	2,385 European ancestry cases, 33,752 European ancestry controls	up to 2,427 European ancestry cases, 3,379 European ancestry controls, 286 Han Chinese ancestry cases, 2,763 Han Chinese ancestry controls	16q22.3	16	72995261	ZFHX3	ZFHX3			ENSG00000140836	NA	NA	rs7193343-T	rs7193343	0	7193343	intron_variant	0	NR	1e-10	10		1.21	[1.14-1.29]	Illumina [303136]	N
2011-01-14	21059979	Shen H	2010-11-08	Arch Intern Med	www.ncbi.nlm.nih.gov/pubmed/21059979	Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish.	LDL cholesterol	841 Amish individuals	663 Amish inidividuals	2p24.1	2	20703255	APOB	LDAH			ENSG00000118961	NA	NA	rs4971516-?	rs4971516	0	4971516	intron_variant	0	0.06	2e-40	39.698970004336	(total cholesterol)	NA		Affymetrix [369241]	N
2011-01-14	21059979	Shen H	2010-11-08	Arch Intern Med	www.ncbi.nlm.nih.gov/pubmed/21059979	Familial defective apolipoprotein B-100 and increased low-density lipoprotein cholesterol and coronary artery calcification in the old order amish.	LDL cholesterol	841 Amish individuals	663 Amish inidividuals	2p24.1	2	20703255	APOB	LDAH			ENSG00000118961	NA	NA	rs4971516-?	rs4971516	0	4971516	intron_variant	0	0.06	2e-52	51.698970004336	(LDL)	NA		Affymetrix [369241]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	2q24.2	2	162404181	IFIH1	KCNH7			ENSG00000184611	NA	NA	rs17716942-A	rs17716942	0	17716942	intron_variant	0	0.86	1e-13	13		1.29	[1.17-1.43]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	2p16.1	2	60854407	REL	LINC01185			ENSG00000228414	NA	NA	rs702873-G	rs702873	0	702873	intron_variant	0	0.56	4e-09	8.39794000867204		1.12	[1.04-1.20]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	3p24.3	3	18742931	intergenic	SATB1-AS1			ENSG00000228956	NA	NA	rs6809854-G	rs6809854	0	6809854	intron_variant	0	0.19	1e-07	7		1.14	[1.04-1.26]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	5q15	5	96766240	ERAP1	ERAP1, CAST			ENSG00000164307, ENSG00000153113	NA	NA	rs27524-A	rs27524	0	27524	intron_variant	0	0.36	3e-11	10.5228787452803		1.13	[1.05-1.22]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	6q21	6	111352511	TRAF3IP2	REV3L, MFSD4B			ENSG00000009413, ENSG00000173214	NA	NA	rs240993-A	rs240993	0	240993	intron_variant	0	0.25	5e-20	19.301029995664		1.25	[1.16-1.34]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	19p13.2	19	10359299	TYK2	TYK2			ENSG00000105397	NA	NA	rs12720356-A	rs12720356	0	12720356	missense_variant	0	0.90	4e-11	10.397940008672		1.4	[1.23-1.61]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	5q33.3	5	159323761	IL12B	IL12B, AC008691.1			ENSG00000113302, ENSG00000249738	NA	NA	rs3213094-?	rs3213094	0	3213094	intron_variant	0	NR	5e-11	10.301029995664		1.39	[1.26-1.53]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	6p21.33	6	31306778	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs10484554-?	rs10484554	0	10484554	intron_variant	0	NR	4e-214	213.397940008672		4.66	[4.23-5.13]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	6q23.3	6	137878280	TNFAIP3	TNFAIP3			ENSG00000118503	NA	NA	rs610604-?	rs610604	0	610604	intron_variant	0	NR	7e-07	6.15490195998574		1.22	[1.13-1.32]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	19p13.2	19	10362257	TYK2	TYK2			ENSG00000105397	NA	NA	rs280519-A	rs280519	0	280519	splice_region_variant	0	0.47	4e-09	8.39794000867204		1.13	[1.05-1.21]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	1q21.3	1	152578800	LCE3D	LCE3E - LCE3D	ENSG00000185966	ENSG00000163202		12020	581	rs4112788-?	rs4112788	0	4112788	intergenic_variant	1	NR	3e-10	9.52287874528034		1.29	[1.19-1.40]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	1p36.11	1	24193430	IL28RA	IFNLR1 - LINC02800	ENSG00000185436	ENSG00000230023		5471	6810	rs4649203-A	rs4649203	0	4649203	intergenic_variant	1	0.73	7e-08	7.15490195998574		1.13	[1.05-1.22]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	14q13.2	14	35363460	NFKBIA	AL133163.2			ENSG00000258860	NA	NA	rs8016947-C	rs8016947	0	8016947	intron_variant	0	0.57	2e-11	10.698970004336		1.19	[1.11-1.27]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	6q21	6	111374888	TRAF3IP2	MFSD4B, REV3L			ENSG00000173214, ENSG00000009413	NA	NA	rs458017-G	rs458017	0	458017	missense_variant	0	0.06	2e-16	15.698970004336		1.37	[1.22-1.54]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	1p31.3	1	67240275	IL23R	IL23R			ENSG00000162594	NA	NA	rs11209026-?	rs11209026	0	11209026	missense_variant	0	NR	7e-07	6.15490195998574		1.49	[1.27-1.74]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	12q13.3	12	56344189	IL23A	STAT2			ENSG00000170581	NA	NA	rs2066808-?	rs2066808	0	2066808	intron_variant	0	NR	2e-07	6.69897000433602		1.49	[1.28-1.73]	Illumina [535475]	N
2011-01-18	20953190	Strange A	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Psoriasis	2,178 European ancestry cases, 5,175 European ancestry controls	3,174 European ancestry cases, 5,464 European ancestry controls	20q13.13	20	49938440	ZNF313	RNF114			ENSG00000124226	NA	NA	rs2235617-?	rs2235617	0	2235617	intron_variant	0	NR	2e-06	5.69897000433602		1.2	[1.11-1.30]	Illumina [535475]	N
2009-09-29	19734903	Lambert JC	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734903	Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.	Alzheimer's disease	2,032 European ancestry cases, 5,328 European ancestry controls	3,978 European ancestry cases, 3,297 European ancestry controls	8p21.1	8;8;8	27611345;27598736;27607002	CLU	CLU; CLU; CLU				NA	NA	rs9331888-G; rs2279590-C; rs11136000-C	rs9331888; rs2279590; rs11136000	0	NA	5_prime_UTR_variant; non_coding_transcript_exon_variant; intron_variant	NA	0.26	6e-10	9.22184874961636		1.22	[1.14-1.29]	Illumina [537029]	N
2009-09-29	19734903	Lambert JC	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734903	Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.	Alzheimer's disease	2,032 European ancestry cases, 5,328 European ancestry controls	3,978 European ancestry cases, 3,297 European ancestry controls	1q32.2	1;1	207518704;207611623	CR1	CR1; CR1				NA	NA	rs6656401-A; rs3818361-A	rs6656401; rs3818361	0	NA	intron_variant; intron_variant	NA	0.18	3e-10	9.52287874528034	(AA)	1.22	[1.15-1.30]	Illumina [537029]	N
2009-09-29	19734903	Lambert JC	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734903	Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.	Alzheimer's disease	2,032 European ancestry cases, 5,328 European ancestry controls	3,978 European ancestry cases, 3,297 European ancestry controls	19q13.32	19	44892362	APOE	TOMM40			ENSG00000130204	NA	NA	rs2075650-?	rs2075650	0	2075650	intron_variant	0	0.90	2e-16	15.698970004336		NA		Illumina [537029]	N
2013-01-11	23118974	Candille SI	2012-10-31	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23118974	Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations.	Eye color	175 European ancestry individuals	293 European ancestry individuals	15q13.1	15	28285036	HERC2, OCA2	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs1667394-C	rs1667394	0	1667394	intron_variant	0	0.28	2e-20	19.698970004336	(Eye color)	0.353	[0.28-0.42] unit increase	Illumina [313763]	N
2013-01-11	23118974	Candille SI	2012-10-31	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23118974	Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations.	Eye color	175 European ancestry individuals	293 European ancestry individuals	5q21.3	5	108064804	FBXL17	FBXL17			ENSG00000145743	NA	NA	rs288139-A	rs288139	0	288139	intron_variant	0	0.21	1e-06	6	(Eye color)	0.206	[0.12-0.29] unit increase	Illumina [313763]	N
2013-01-11	23118974	Candille SI	2012-10-31	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23118974	Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations.	Eye color	175 European ancestry individuals	293 European ancestry individuals	8q24.22	8	131341488	ADCY8/EFR3A	AC104257.1 - SNORA72	ENSG00000253507	ENSG00000207249		23856	91288	rs4596632-C	rs4596632	0	4596632	intergenic_variant	1	0.33	3e-06	5.52287874528034	(Eye color)	0.167	[0.098-0.236] unit increase	Illumina [313763]	N
2011-06-25	21659334	Tanaka Y	2011-06-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21659334	Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.	Response to hepatitis C treatment	303 Japanese ancestry cases	391 Japanese ancestry cases	20p13	20	3204477	DDRGK1	DDRGK1			ENSG00000198171	NA	NA	rs11697186-T	rs11697186	0	11697186	intron_variant	0	0.15	5e-17	16.301029995664	(Decrease of PLT)	4.5	[3.10-6.50]	Affymetrix [595052]	N
2011-06-25	21659334	Tanaka Y	2011-06-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21659334	Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.	Response to hepatitis C treatment	303 Japanese ancestry cases	391 Japanese ancestry cases	20p13	20	3207087	ITPA	DDRGK1 - ITPA	ENSG00000198171	ENSG00000125877		2402	1781	rs6139030-C	rs6139030	0	6139030	intergenic_variant	1	0.17	1e-15	15	(Decrease of PLT)	3.9	[2.80-5.50]	Affymetrix [595052]	N
2011-06-25	21659334	Tanaka Y	2011-06-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21659334	Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.	Response to hepatitis C treatment	303 Japanese ancestry cases	391 Japanese ancestry cases	20p13	20	3204477	DDRGK1	DDRGK1			ENSG00000198171	NA	NA	rs11697186-A	rs11697186	0	11697186	intron_variant	0	0.85	9e-25	24.0457574905607	(Change in Hb)	33.33	[12.50-100]	Affymetrix [595052]	N
2011-06-25	21659334	Tanaka Y	2011-06-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21659334	Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C.	Response to hepatitis C treatment	303 Japanese ancestry cases	391 Japanese ancestry cases	20p13	20	3207087	ITPA	DDRGK1 - ITPA	ENSG00000198171	ENSG00000125877		2402	1781	rs6139030-T	rs6139030	0	6139030	intergenic_variant	1	0.83	2e-25	24.698970004336	(Change of Hb)	25	[11.11-50.0]	Affymetrix [595052]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	11p13	11	34533644	ELF5	AL137224.1			ENSG00000255271	NA	NA	rs836132-C	rs836132	0	836132	intron_variant	0	0.15	5e-08	7.30102999566398		0.65	unit increase	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	11p15.4	11	9090011	SCUBE2	AC079296.2, SCUBE2			ENSG00000286935, ENSG00000175356	NA	NA	rs963167-C	rs963167	0	963167	non_coding_transcript_exon_variant	0	0.15	1e-07	7		0.65	unit increase	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	11p15.4	11	9087740	SCUBE2	SCUBE2			ENSG00000175356	NA	NA	rs2647528-C	rs2647528	0	2647528	intron_variant	0	0.17	3e-07	6.52287874528034		0.59	unit increase	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	17q24.1	17	66137608	CEP112	CEP112			ENSG00000154240	NA	NA	rs7209395-T	rs7209395	0	7209395	intron_variant	0	0.34	7e-07	6.15490195998574		0.44	unit increase	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	17q24.2	17	66240200	APOH	APOH			ENSG00000091583	NA	NA	rs10048158-C	rs10048158	0	10048158	intron_variant	0	0.5	1e-06	6		0.41	unit decrease	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	17q24.1	17	66102427	CEP112	CEP112			ENSG00000154240	NA	NA	rs2319125-C	rs2319125	0	2319125	intron_variant	0	0.46	1e-06	6		0.42	unit increase	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	20q13.33	20	61806743	CDH4	CDH4			ENSG00000179242	NA	NA	rs4925295-A	rs4925295	0	4925295	intron_variant	0	0.16	2e-06	5.69897000433602		0.52	unit decrease	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	5p14.1	5	25692864	CDH10, CDH9	AC022140.1 - RNU6-374P	ENSG00000248605	ENSG00000201016		246939	8353	rs193741-A	rs193741	0	193741	intergenic_variant	1	0.14	2e-06	5.69897000433602		0.64	unit decrease	Illumina [283437]	N
2013-03-19	23279374	Athanasiadis G	2013-01-02	J Thromb Haemost	www.ncbi.nlm.nih.gov/pubmed/23279374	Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain.	&beta;2-Glycoprotein I (&beta;2-GPI) plasma levels	306 European ancestry individuals	NA	10q24.2	10	99605556	SLC25A28	NKX2-3 - SLC25A28	ENSG00000119919	ENSG00000155287		69032	4966	rs11190179-G	rs11190179	0	11190179	regulatory_region_variant	1	0.12	2e-06	5.69897000433602		0.65	unit increase	Illumina [283437]	N
2009-09-04	19651812	Chambers JC	2009-08-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/19651812	Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians.	Fasting plasma glucose	698 Asian Indian ancestry cases, 6,776 Asian Indian ancestry controls	4,462 European ancestry controls	11q14.3	11	92958366	MTNR1B	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		20700	7431	rs2166706-G	rs2166706	0	2166706	intergenic_variant	1	0.46	2e-09	8.69897000433602		0.07	(0.04-0.09) mmol/L increase	Illumina [up to 544390]	N
2013-06-18	23561647	van Setten J	2013-03-13	Atherosclerosis	www.ncbi.nlm.nih.gov/pubmed/23561647	Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.	Coronary artery calcification	2,620 European ancestry males	NA	15q25.1	15	78796769	ADAMTS7	ADAMTS7			ENSG00000136378	NA	NA	rs3825807-A	rs3825807	0	3825807	missense_variant	0	0.57	7e-06	5.15490195998574		0.363	[0.21-0.52] unit increase	Illumina [2500000] (imputed)	N
2013-06-18	23561647	van Setten J	2013-03-13	Atherosclerosis	www.ncbi.nlm.nih.gov/pubmed/23561647	Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.	Coronary artery calcification	2,620 European ancestry males	NA	9p21.3	9	22084311	CDKN2A, CDKN2B	CDKN2B-AS1			ENSG00000240498	NA	NA	rs1537370-T	rs1537370	0	1537370	intron_variant	0	0.46	2e-11	10.698970004336		0.532	[0.38-0.69] unit increase	Illumina [2500000] (imputed)	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	3q26.2	3	169800667	LRRC34	LRRC34			ENSG00000171757	NA	NA	rs6793295-C	rs6793295	0	6793295	missense_variant	0	0.26	8e-13	12.0969100130081		1.3	[1.19-1.42]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-A	rs2736100	0	2736100	3_prime_UTR_variant	0	0.49	2e-19	18.698970004336		1.37	[1.27-1.49]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	6p24.3	6	7562999	DSP	DSP			ENSG00000096696	NA	NA	rs2076295-G	rs2076295	0	2076295	intron_variant	0	0.44	1e-19	19		1.43	[1.32-1.55]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	7q22.1	7	99995723	intergenic	AC004522.2 - AC004522.5	ENSG00000235713	ENSG00000286923		2673	1967	rs4727443-C	rs4727443	0	4727443	intergenic_variant	1	0.39	1e-08	8		1.3	[1.20-1.41]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	8p23.2	8	4760288	NR	CSMD1			ENSG00000183117	NA	NA	rs1379326-C	rs1379326	0	1379326	intron_variant	0	0.26	1e-07	7		1.78	[1.45-2.19]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	11p15.5	11	1100037	MUC2	MUC2, MUC2, MUC2			ENSG00000198788, ENSG00000278466, ENSG00000284971	NA	NA	rs7934606-T	rs7934606	0	7934606	intron_variant	0	0.42	7e-34	33.1549019599857		1.52	[1.40-1.65]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	13q34	13	112882313	ATP11A	ATP11A			ENSG00000068650	NA	NA	rs1278769-G	rs1278769	0	1278769	3_prime_UTR_variant	0	0.76	7e-09	8.15490195998574		1.27	[1.14-1.39]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	15q15.1	15	40425103	intergenic	IVD			ENSG00000128928	NA	NA	rs2034650-A	rs2034650	0	2034650	intron_variant	0	0.51	1e-11	11		1.3	[1.19-1.41]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	19p13.3	19	4717660	DPP9	DPP9			ENSG00000142002	NA	NA	rs12610495-G	rs12610495	0	12610495	missense_variant	0	0.29	2e-12	11.698970004336		1.29	[1.18-1.41]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	4q22.1	4	88890044	FAM13A	FAM13A			ENSG00000138640	NA	NA	rs2609255-G	rs2609255	0	2609255	intron_variant	0	0.21	2e-11	10.698970004336		1.29	[1.18-1.42]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	10q24.33	10	103913084	OBFC1	STN1			ENSG00000107960	NA	NA	rs11191865-A	rs11191865	0	11191865	intron_variant	0	0.49	2e-08	7.69897000433602		1.25	[1.15-1.35]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	17q21.31	17	45979401	MAPT	MAPT, MAPT, MAPT			ENSG00000277956, ENSG00000276155, ENSG00000186868	NA	NA	rs1981997-G	rs1981997	0	1981997	non_coding_transcript_exon_variant	0	0.77	9e-14	13.0457574905607		1.41	[1.28-1.56]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	15q25.3	15	85524075	NR	AKAP13			ENSG00000170776	NA	NA	rs6496044-G	rs6496044	0	6496044	intron_variant	0	0.33	2e-06	5.69897000433602		1.25	[1.15-1.36]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	6p21.32	6	32222251	NR	NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4, NOTCH4			ENSG00000235396, ENSG00000223355, ENSG00000204301, ENSG00000232339, ENSG00000234876, ENSG00000206312, ENSG00000238196	NA	NA	rs3132946-A	rs3132946	0	3132946	intron_variant	0	0.12	8e-06	5.09691001300806		1.38	[1.21-1.57]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	8q24.12	8	119941633	NR	DEPTOR			ENSG00000155792	NA	NA	rs7005380-G	rs7005380	0	7005380	intron_variant	0	0.63	2e-07	6.69897000433602		1.25	[1.15-1.37]	Illumina [439828]	N
2013-11-01	23583980	Fingerlin TE	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583980	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	Interstitial lung disease	1,161 European ancestry cases, 4,683 European ancestry controls	876 European ancestry cases, 1,890 European ancestry controls	10q21.3	10	66465128	NR	CTNNA3			ENSG00000183230	NA	NA	rs2441727-G	rs2441727	0	2441727	intron_variant	0	0.05	1e-06	6		1.35	[1.15-1.60]	Illumina [439828]	N
2013-06-18	23536807	Scheetz TE	2013-03-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23536807	A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci.	Age-related macular degeneration	200 cases, 197 controls	200 cases, 200 controls				CFHR2, CFHR4, F13B, ASPM, CFHR3, CFHR5, ZBTB41, KCNT2, CFH, CFHR1P					NA	NA	SNP_A-2171106-?	SNP_A-2171106	0	NA		1	0.39	1e-16	16		3.75	[2.91-4.82]	Affymetrix [500000]	N
2013-06-18	23536807	Scheetz TE	2013-03-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23536807	A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci.	Age-related macular degeneration	200 cases, 197 controls	200 cases, 200 controls				ARMS2, PLEKHA1, HTRA1					NA	NA	SNP_A-1841655-?	SNP_A-1841655	0	NA		1	0.20	1e-16	16		3.14	[2.49-3.97]	Affymetrix [500000]	N
2013-06-20	23496005	Luca G	2013-03-18	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/23496005	Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.	Narcolepsy with cataplexy	585 European ancestry cases	387 European ancestry cases	19q12	19	31667558	NR	RNA5SP471 - RNU6-967P	ENSG00000252780	ENSG00000201894		12097	119590	rs16966122-?	rs16966122	0	16966122	intergenic_variant	1	NR	2e-06	5.69897000433602	(ESS)	1.601	[NR] unit decrease	NR [NR]	N
2013-06-20	23496005	Luca G	2013-03-18	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/23496005	Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.	Narcolepsy with cataplexy	585 European ancestry cases	387 European ancestry cases	8q12.1	8	58411603	UBXN2B	UBXN2B			ENSG00000215114	NA	NA	rs2859998-?	rs2859998	0	2859998	intron_variant	0	NR	1e-07	7	(Age EDS onset)	4.4145	[NR] unit decrease	NR [NR]	N
2013-06-20	23496005	Luca G	2013-03-18	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/23496005	Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.	Narcolepsy with cataplexy	585 European ancestry cases	387 European ancestry cases	12p13.33	12	3055757	TEAD4	AC125807.2 - AC125807.1	ENSG00000250899	ENSG00000234589		10807	15775	rs12425451-?	rs12425451	0	12425451	TF_binding_site_variant	1	NR	2e-07	6.69897000433602	(Age cataplexy onset)	6.7866	[NR] unit decrease	NR [NR]	N
2013-06-20	23496005	Luca G	2013-03-18	J Sleep Res	www.ncbi.nlm.nih.gov/pubmed/23496005	Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study.	Narcolepsy with cataplexy	585 European ancestry cases	387 European ancestry cases	20q13.13	20	48763274	NR	PREX1			ENSG00000124126	NA	NA	rs2426087-?	rs2426087	0	2426087	intron_variant	0	NR	2e-06	5.69897000433602	(SE)	10.463	[NR] unit increase	NR [NR]	N
2013-06-21	23502781	Germain M	2013-03-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23502781	Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension.	Pulmonary arterial hypertension (without BMPR2 mutations)	340 European ancestry cases, 1,068 European ancestry controls	285 cases, 457 controls	18q22.3	18	72483704	CBLN2	AC069114.1 - CBLN2	ENSG00000265995	ENSG00000141668		539127	52976	rs2217560-G	rs2217560	0	2217560	intergenic_variant	1	0.069	7e-10	9.15490195998574		1.97	[1.59-2.45]	Illumina [462499]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	4q12	4	53464700	FIP1L1, LNX1	LNX1, AC058822.1			ENSG00000072201, ENSG00000282278	NA	NA	rs2412488-A	rs2412488	0	2412488	intron_variant	0	0.29	9e-07	6.04575749056067	(H19-ICR)	NA		Illumina [515966]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	NR	2e-06	5.69897000433602	(AA)	NA		Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	134391	Alpha-globin cluster	NPRL3			ENSG00000103148	NA	NA	rs7203560-G	rs7203560	0	7203560	intron_variant	0	0.06801	5e-62	61.301029995664	(AA)	1.255	[1.11-1.4] unit decrease	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	0.4408	5e-14	13.301029995664	(EA)	0.2343	[0.17-0.3] unit decrease	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.2615	4e-13	12.397940008672	(EA)	0.2534	[0.19-0.32] unit increase	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	0.4408	7e-19	18.1549019599857		0.2326	[0.18-0.28] unit decrease	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	190281	Alpha-globin cluster	LUC7L			ENSG00000007392	NA	NA	rs1211375-A	rs1211375	0	1211375	intron_variant	0	NR	3e-17	16.5228787452803		0.2115	[0.16-0.26] unit decrease	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	6q23.3	6	135097880	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs9399137-T	rs9399137	0	9399137	intron_variant	0	NR	4e-15	14.397940008672		0.2519	[0.19-0.31] unit decrease	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	NR	7e-09	8.15490195998574		0.3558	[0.24-0.48] unit increase	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	6q24.1	6	139514552	CITED2	AL592429.2			ENSG00000226571	NA	NA	rs668459-T	rs668459	0	668459	intron_variant	0	NR	9e-09	8.04575749056067		0.139	[0.092-0.186] unit decrease	Illumina [544917]	N
2013-03-20	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin	7,943 African American children, 6,234 European ancestry children	NA	9p24.1	9	4845520	RCL1	RCL1			ENSG00000120158	NA	NA	rs10815094-A	rs10815094	0	10815094	intron_variant	0	NR	5e-06	5.30102999566398		0.1461	[0.083-0.209] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	1q23.3	1	161976937	DARC	ATF6 - OLFML2B	ENSG00000118217	ENSG00000162745		12867	6255	rs2340727-A	rs2340727	0	2340727	intergenic_variant	1	NR	2e-23	22.698970004336	(WBC)	0.0229	[0.018-0.027] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	NR	2e-06	5.69897000433602	(HGB)	0.1944	[0.11-0.27] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	6q23.3	6	135097880	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs9399137-T	rs9399137	0	9399137	intron_variant	0	NR	3e-06	5.52287874528034	(RBC)	0.0361	[0.021-0.051] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	6p21.33	6	31090563	PSORS1C1, MUC21, HCG22, C6orf15, CCHCR1, CDSN, PSORS1C2	RNU6-1133P - C6orf15	ENSG00000222895	ENSG00000229432		7454	20660	rs3130544-A	rs3130544	0	3130544	intergenic_variant	1	NR	5e-07	6.30102999566398	(WBC)	0.0189	[0.011-0.026] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	11p15.4	11	5281833	HBE1, HBD, HBBP1, HBG1, HBB	HBE1, HBG2, AC104389.5			ENSG00000213931, ENSG00000196565, ENSG00000239920	NA	NA	rs2213169-T	rs2213169	0	2213169	intron_variant	0	0.1362	5e-11	10.301029995664	(AA, HCT)	0.4471	[0.31-0.58] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	134391	Alpha-globin cluster	NPRL3			ENSG00000103148	NA	NA	rs7203560-G	rs7203560	0	7203560	intron_variant	0	0.06801	2e-08	7.69897000433602	(AA, HGB)	0.199	[0.13-0.27] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	134391	Alpha-globin cluster	NPRL3			ENSG00000103148	NA	NA	rs7203560-G	rs7203560	0	7203560	intron_variant	0	0.06801	2e-23	22.698970004336	(AA, RBC)	0.1452	[0.12-0.17] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	Xq28	X	154785832	MPP1	MPP1			ENSG00000130830	NA	NA	rs5987027-T	rs5987027	0	5987027	intron_variant	0	0.2462	1e-11	11	(AA, RBC)	0.0745	[0.053-0.096] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	1q23.1	1	159001296	DARC	IFI16			ENSG00000163565	NA	NA	rs4657616-G	rs4657616	0	4657616	intron_variant	0	0.099	5e-47	46.301029995664	(AA, WBC)	0.0612	[0.053-0.07] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	6p21.33	6	31973120	CFB, STK19, ZBTB12	STK19			ENSG00000234947	NA	NA	rs389884-C	rs389884	0	389884	non_coding_transcript_exon_variant	0	0.0953	2e-08	7.69897000433602	(EA, WBC)	0.0254	[0.017-0.034] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	0.4408	3e-08	7.52287874528034	(HGB)	0.0896	[0.058-0.121] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Hematology traits	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	190281	Alpha-globin cluster	LUC7L			ENSG00000007392	NA	NA	rs1211375-A	rs1211375	0	1211375	intron_variant	0	NR	7e-14	13.1549019599857	(RBC)	0.0423	[0.031-0.053] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin concentration	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	134391	Alpha-globin cluster	NPRL3			ENSG00000103148	NA	NA	rs7203560-G	rs7203560	0	7203560	intron_variant	0	0.06801	1e-33	33	(AA)	0.5311	[0.45-0.62] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin concentration	7,943 African American children, 6,234 European ancestry children	NA	11p15.4	11	5281833	HBE1, HBD, HBBP1, HBG1, HBB	HBE1, HBG2, AC104389.5			ENSG00000213931, ENSG00000196565, ENSG00000239920	NA	NA	rs2213169-T	rs2213169	0	2213169	intron_variant	0	0.1362	1e-13	13	(AA)	0.2227	[0.16-0.28] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin concentration	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	0.4408	4e-07	6.39794000867204		0.0875	[0.054-0.121] unit decrease	Illumina [544917]	N
2013-03-19	23209189	Tabassum R	2012-12-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/23209189	Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.	Type 2 diabetes	1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls	3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls	2q21.3	2	134722410	TMEM163	AC110620.2			ENSG00000287463	NA	NA	rs6723108-T	rs6723108	0	6723108	non_coding_transcript_exon_variant	0	0.86	7e-08	7.15490195998574	(All South Asians)	1.27	[1.17-1.39]	Illumina [536420]	N
2013-03-19	23209189	Tabassum R	2012-12-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/23209189	Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.	Type 2 diabetes	1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls	3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls	5q11.2	5	56808481	MAP3K1	AC008940.1 - MAP3K1	ENSG00000228650	ENSG00000095015		36178	7068	rs10461617-A	rs10461617	0	10461617	intergenic_variant	1	0.21	4e-06	5.39794000867204	(All South Asians)	1.17	[1.09-1.25]	Illumina [536420]	N
2013-03-19	23209189	Tabassum R	2012-12-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/23209189	Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.	Type 2 diabetes	1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls	3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls	1p22.1	1	91728765	TGFBR3	TGFBR3			ENSG00000069702	NA	NA	rs11165354-A	rs11165354	0	11165354	intron_variant	0	0.78	4e-06	5.39794000867204	(All South Asians)	1.17	[1.10-1.25]	Illumina [536420]	N
2013-03-19	23209189	Tabassum R	2012-12-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/23209189	Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.	Type 2 diabetes	1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls	3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls	10q25.2	10	112998590	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs7903146-T	rs7903146	0	7903146	intron_variant	0	0.30	1e-35	35	(Indo-European South Asians)	1.51	[1.42-1.62]	Illumina [536420]	N
2013-03-19	23209189	Tabassum R	2012-12-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/23209189	Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.	Type 2 diabetes	1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls	3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls	9p21.3	9	22132077	CDKN2A	CDKN2B-AS1 - AL157937.1	ENSG00000240498	ENSG00000236921		3974	71913	rs2383208-T	rs2383208	0	2383208	intergenic_variant	1	0.85	3e-06	5.52287874528034	(Indo-European South Asians)	1.23	[1.13-1.34]	Illumina [536420]	N
2013-03-19	23209189	Tabassum R	2012-12-03	Diabetes	www.ncbi.nlm.nih.gov/pubmed/23209189	Genome-wide association study for type 2 diabetes in Indians identifies a new susceptibility locus at 2q21.	Type 2 diabetes	1,101 Indo-European ancestry cases, 1,027 Indo-European ancestry controls	3,607 Indo-European ancestry cases, 2,924 Indo-European ancestry controls, 1,184 Dravidian ancestry cases, 1,061 Dravidian ancestry controls, 11,285 European ancestry cases, 11,285 European ancestry controls	16q12.2	16	53782363	FTO	FTO			ENSG00000140718	NA	NA	rs8050136-A	rs8050136	0	8050136	intron_variant	0	0.34	6e-06	5.22184874961636	(Indo-European South Asians)	1.16	[1.09-1.24]	Illumina [536420]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin concentration	7,943 African American children, 6,234 European ancestry children	NA	6q23.3	6	135105435	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		2379	75873	rs4895441-A	rs4895441	0	4895441	regulatory_region_variant	1	NR	3e-06	5.52287874528034		0.0928	[0.054-0.132] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin concentration	7,943 African American children, 6,234 European ancestry children	NA	1q32.1	1	203682799	ATP2B4	ATP2B4			ENSG00000058668	NA	NA	rs1541252-?	rs1541252	0	1541252	5_prime_UTR_variant	0	NR	9e-08	7.04575749056067		NA		Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular hemoglobin concentration	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	530124	Alpha-globin cluster	CAPN15			ENSG00000103326	NA	NA	rs2266928-A	rs2266928	0	2266928	intron_variant	0	NR	3e-11	10.5228787452803		0.1178	[0.083-0.152] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	190281	Alpha-globin cluster	LUC7L			ENSG00000007392	NA	NA	rs1211375-A	rs1211375	0	1211375	intron_variant	0	NR	1e-16	16		0.5254	[0.4-0.65] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	Xq28	X	154785832	MPP1	MPP1			ENSG00000130830	NA	NA	rs5987027-T	rs5987027	0	5987027	intron_variant	0	0.2462	4e-10	9.39794000867204	(AA)	0.9159	[0.63-1.2] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.2615	2e-09	8.69897000433602	(EA)	0.5411	[0.37-0.72] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	0.4408	2e-09	8.69897000433602	(EA)	0.479	[0.32-0.64] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-T	rs855791	0	855791	missense_variant	0	0.4408	7e-12	11.1549019599857		0.4566	[0.33-0.59] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	6q23.3	6	135097880	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs9399137-T	rs9399137	0	9399137	intron_variant	0	NR	1e-11	11		0.5546	[0.39-0.71] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	6q24.1	6	139514552	CITED2	AL592429.2			ENSG00000226571	NA	NA	rs668459-T	rs668459	0	668459	intron_variant	0	NR	4e-08	7.39794000867204		0.3363	[0.22-0.46] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	6p21.1	6	41937537	BYSL, USP49, CCND3, MED20	CCND3			ENSG00000112576	NA	NA	rs3218097-T	rs3218097	0	3218097	intron_variant	0	NR	9e-08	7.04575749056067		0.422	[0.27-0.58] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	9p24.1	9	4844265	RCL1	RCL1			ENSG00000120158	NA	NA	rs2236496-T	rs2236496	0	2236496	intron_variant	0	NR	2e-07	6.69897000433602		0.4162	[0.26-0.57] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Mean corpuscular volume	7,943 African American children, 6,234 European ancestry children	NA	16p13.3	16	134391	Alpha-globin cluster	NPRL3			ENSG00000103148	NA	NA	rs7203560-G	rs7203560	0	7203560	intron_variant	0	0.06801	8e-43	42.0969100130081	(AA)	2.555	[2.19-2.92] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	3p14.3	3	56815721	ARHGEF3	ARHGEF3			ENSG00000163947	NA	NA	rs1354034-C	rs1354034	0	1354034	intron_variant	0	0.27	9e-13	12.0457574905607	(AA)	11.44	[8.31-14.57] unit increase	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	6p21.31	6	33572432	BAK1	GGNBP1			ENSG00000204188	NA	NA	rs210134-A	rs210134	0	210134	intron_variant	0	0.2675	2e-08	7.69897000433602	(AA)	8.923	[5.82-12.02] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	3p14.3	3	56815721	ARHGEF3	ARHGEF3			ENSG00000163947	NA	NA	rs1354034-T	rs1354034	0	1354034	intron_variant	0	0.4092	4e-09	8.39794000867204	(EA)	9.443	[6.3-12.59] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	12q13.13	12	54342686	COPZ1	COPZ1, AC078778.1			ENSG00000111481, ENSG00000258344	NA	NA	rs4326844-A	rs4326844	0	4326844	intron_variant	0	0.4493	5e-08	7.30102999566398	(EA)	8.679	[5.57-11.79] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	3p14.3	3	56815721	ARHGEF3	ARHGEF3			ENSG00000163947	NA	NA	rs1354034-T	rs1354034	0	1354034	intron_variant	0	NR	1e-19	19		10.4352	[8.18-12.69] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	6p21.31	6	33573942	BAK1	GGNBP1, BAK1			ENSG00000204188, ENSG00000030110	NA	NA	rs513349-A	rs513349	0	513349	intron_variant	0	NR	2e-12	11.698970004336		7.7549	[5.59-9.92] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	10q21.3	10	63203689	JMJD1C	JMJD1C			ENSG00000171988	NA	NA	rs4379723-T	rs4379723	0	4379723	intron_variant	0	NR	7e-07	6.15490195998574		5.4297	[3.28-7.58] unit decrease	Illumina [544917]	N
2013-03-15	23263863	Li J	2012-12-20	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23263863	GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.	Platelet count	7,943 African American children, 6,234 European ancestry children	NA	9p24.1	9	4834394	RCL1	RCL1			ENSG00000120158	NA	NA	rs457287-A	rs457287	0	457287	intron_variant	0	NR	1e-06	6		5.987	[3.55-8.42] unit decrease	Illumina [544917]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	3p26.2	3	2854000	CNTN4	CNTN4			ENSG00000144619	NA	NA	rs11713158-?	rs11713158	0	11713158	intron_variant	0	NR	9e-07	6.04575749056067	(High intelligence)	5.04	[3.06-7.02] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	10q21.2	10	62463624	ZNF365	ZNF365, AC024598.1			ENSG00000138311, ENSG00000285837	NA	NA	rs10995170-?	rs10995170	0	10995170	intron_variant	0	NR	3e-07	6.52287874528034	(High intelligence)	4.42	[2.77-6.07] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	7q21.3	7	94380322	COL1A2	AC002074.1			ENSG00000285090	NA	NA	rs7792596-?	rs7792596	0	7792596	non_coding_transcript_exon_variant	0	NR	6e-07	6.22184874961636	(High intelligence)	4.13	[2.52-5.74] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	9p13.2	9;9;9;9	36998996;37002118;37000690;36997420	PAX5	PAX5; PAX5; PAX5; PAX5				NA	NA	rs1329573-?; rs7020413-?; rs3824344-?; rs3758171-?	rs1329573; rs7020413; rs3824344; rs3758171	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	4e-08	7.39794000867204	(Neurodevelopment)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	19q13.33	19;19;19;19	48022250;48027959;48019612;48024325	ELSPBP1	ELSPBP1; ELSPBP1 - CABP5; ELSPBP1; ELSPBP1				NA	NA	rs2303690-?; rs2560966-?; rs3815908-?; rs3936340-?	rs2303690; rs2560966; rs3815908; rs3936340	0	NA	missense_variant; intergenic_variant; intron_variant; intron_variant	NA	NR	3e-08	7.52287874528034		NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	2q33.1	2;2;2;2	200706420;200716231;200717470;200711561	AOX1	AOX3P-AOX2P; AOX3P; LINC01792; AOX3P-AOX2P; AOX3P; LINC01792; AOX3P-AOX2P; AOX3P; LINC01792; AOX3P-AOX2P; AOX3P				NA	NA	rs2540051-?; rs7589014-?; rs2348114-?; rs7563911-?	rs2540051; rs7589014; rs2348114; rs7563911	0	NA	splice_donor_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant	NA	NR	6e-08	7.22184874961636	(Amyotrophic Lateral Sclerosis)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	1p35.1	1;1;1;1	33720593;33723829;33716230;33715242	CSMD2	CSMD2; CSMD2; CSMD2; CSMD2				NA	NA	rs528059-?; rs544991-?; rs7533254-?; rs16835742-?	rs528059; rs544991; rs7533254; rs16835742	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	8e-08	7.09691001300806	(Brain structure)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	10p15.1	10;10;10;10	5307908;5312714;5311727;5306374	UCN3	RPL26P28 - AL683826.1; RPL26P28 - AL683826.1; RPL26P28 - AL683826.1; RPL26P28 - AL683826.1				NA	NA	rs7475343-?; rs7896729-?; rs9423406-?; rs1987511-?	rs7475343; rs7896729; rs9423406; rs1987511	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	NR	9e-08	7.04575749056067	(Depression; med response/addiction)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	3p26.2	3;3;3;3	2851590;2839891;2844843;2854000	CNTN4	CNTN4; CNTN4; CNTN4; CNTN4				NA	NA	rs4629318-?; rs6781149-?; rs17584516-?; rs11713158-?	rs4629318; rs6781149; rs17584516; rs11713158	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	1e-07	7	(Cell adhesion; neurodevelopment)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	11p14.3	11;11;11;11	24718258;24720113;24718888;24720211	LUZP2	LUZP2; LUZP2; LUZP2; LUZP2				NA	NA	rs10834449-?; rs12798374-?; rs2716458-?; rs1021261-?	rs10834449; rs12798374; rs2716458; rs1021261	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	8e-08	7.09691001300806	(Prader-Willi syndrome; verbal memory)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	4q28.3	4;4;4;4	130210261;130211745;130206478;130212336	CYCSP14	LINC02465 - LINC02479; LINC02465 - LINC02479; LINC02465 - LINC02479; LINC02465 - LINC02479				NA	NA	rs11099040-?; rs13113376-?; rs1908039-?; rs1908038-?	rs11099040; rs13113376; rs1908039; rs1908038	0	NA	intergenic_variant; intergenic_variant; intergenic_variant; intergenic_variant	NA	NR	9e-08	7.04575749056067		NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	22q12.3	22	31833663	DEPDC5	DEPDC5, Z82190.2			ENSG00000100150, ENSG00000285404	NA	NA	rs5994434-?	rs5994434	0	5994434	intron_variant	0	NR	5e-07	6.30102999566398	(Average Intelligence)	6.29	[3.88-8.70] unit decrease	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	8p22	8	15808103	TUSC3	PPM1AP1 - AC018437.3	ENSG00000250483	ENSG00000287476		820	88164	rs240657-?	rs240657	0	240657	intergenic_variant	1	NR	2e-06	5.69897000433602	(Average Intelligence)	5.22	[3.10-7.34] unit decrease	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	20p12.1	20;20;20;20	16475129;16470997;16480070;16478664	KIF16B	KIF16B; KIF16B; KIF16B; KIF16B				NA	NA	rs932541-?; rs6043979-?; rs6044003-?; rs6044001-?	rs932541; rs6043979; rs6044003; rs6044001	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	1e-08	8	(Synaptic signaling, transport)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	2q14.3	2	126573377	GYPC	YWHAZP2 - GYPC	ENSG00000213236	ENSG00000136732		15215	82756	rs1550404-?	rs1550404	0	1550404	intergenic_variant	1	NR	1e-06	6	(high intelligence)	7.05	[4.23-9.87] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	19q13.33	19	48024325	ELSPBP1	ELSPBP1			ENSG00000169393	NA	NA	rs3936340-?	rs3936340	0	3936340	intron_variant	0	NR	2e-06	5.69897000433602	(High intelligence)	6.8	[4.06-9.54] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	18q23	18	75480491	C18orf62	AC012101.1 - AC090812.1	ENSG00000286603	ENSG00000287295		5719	25736	rs1865721-?	rs1865721	0	1865721	intergenic_variant	1	NR	5e-06	5.30102999566398	(High intelligence)	3.9	[2.25-5.55] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	1p13.3	1	106921021	PRMT6	LINC01661 - PRMT6	ENSG00000237460	ENSG00000198890		55705	135653	rs12125971-?	rs12125971	0	12125971	intergenic_variant	1	NR	7e-06	5.15490195998574	(High intelligence)	6.93	[3.99-9.87] unit increase	Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	22q12.2	22;22;22;22	31631463;31628994;31653931;31629927	PISD	PISD; PISD; PISD; PISD				NA	NA	rs12627933-?; rs11703808-?; rs9621305-?; rs761746-?	rs12627933; rs11703808; rs9621305; rs761746	0	NA	intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant	NA	NR	7e-08	7.15490195998574		NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	9q34.2	9;9;9;9	134389093;134393077;134393657;134377610	RXRA	RXRA; RXRA; RXRA; RXRA				NA	NA	rs35079168-?; rs4501664-?; rs11102986-?; rs34312136-?	rs35079168; rs4501664; rs11102986; rs34312136	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	8e-08	7.09691001300806	(Schizophrenia, Cognitive ability)	NA		Illumina [795637]	N
2012-04-25	22449649	Loo SK	2012-02-28	J Am Acad Child Adolesc Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22449649	Genome-wide association study of intelligence: additive effects of novel brain expressed genes.	Intelligence	656 European ancestry individuals from ADHD families	NA	7q21.3	7;7;7;7	94377682;94371161;94373948;94379223	COL1A2	AC002074.1; AC002074.1; AC002074.1; AC002074.1				NA	NA	rs13221576-?; rs10262915-?; rs6465411-?; rs4729127-?	rs13221576; rs10262915; rs6465411; rs4729127	0	NA	intron_variant; intron_variant; intron_variant; intron_variant	NA	NR	9e-08	7.04575749056067		NA		Illumina [795637]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	11p15.5	11	2003314	H19, MIR675	H19 - IGF2	ENSG00000130600	ENSG00000167244		1844	125798	rs4930103-A	rs4930103	0	4930103	regulatory_region_variant	1	0.49	5e-16	15.301029995664	(H19-ICR-CpG02)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	11q21	11	93051037	RPL26P31	MTNR1B - RPL26P31	ENSG00000134640	ENSG00000242807		65971	1358	rs7931462-G	rs7931462	0	7931462	intergenic_variant	1	0.02	2e-09	8.69897000433602	(KvDMR 10-11-12)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	2q24.3	2	167302841	intergenic	AC073050.1			ENSG00000228222	NA	NA	rs10497324-A	rs10497324	0	10497324	intron_variant	0	0.04	2e-09	8.69897000433602	(KvDMR 21)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	3q13.13	3	110070723	intergenic	AC078918.1 - AC117430.1	ENSG00000243945	ENSG00000240895		92956	456759	rs10934011-G	rs10934011	0	10934011	regulatory_region_variant	1	0.21	1e-09	9	(NESPAS CpG08_09)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	4q28.3	4	136605429	TERF1P3	AC093875.1 - LINC02511	ENSG00000279749	ENSG00000248869		51690	190490	rs10012307-T	rs10012307	0	10012307	intergenic_variant	1	0.06	2e-08	7.69897000433602	(H19-ICR CpG 09-10)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	22q11.21	22	19703979	GP1BB, AC000093.3, TBX1, SEPT5	AC000067.1 - SEPTIN5	ENSG00000225007	ENSG00000184702		36424	10524	rs4819833-C	rs4819833	0	4819833	regulatory_region_variant	1	0.34	6e-08	7.22184874961636	(IGF2-DMR CpG01)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (parent-of-origin)	1,024 European ancestry individuals	NA	4q31.3	4	153943598	intergenic	SFRP2 - AC079298.3	ENSG00000145423	ENSG00000280241		154515	5120	rs13135284-C	rs13135284	0	13135284	intergenic_variant	1	0.26	5e-08	7.30102999566398	(NESPAS CpG02)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	11p15.5	11	1963897	H19, IGF2, MRPL23	MRPL23			ENSG00000214026	NA	NA	rs10769945-T	rs10769945	0	10769945	intron_variant	0	0.48	5e-07	6.30102999566398	(H19-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	11p15.5	11	2003314	H19	H19 - IGF2	ENSG00000130600	ENSG00000167244		1844	125798	rs4930103-G	rs4930103	0	4930103	regulatory_region_variant	1	0.397	1e-14	14	(H19-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	11p15.4	11	6501574	FXC1, DNHD1	DNHD1, AC084337.2			ENSG00000179532, ENSG00000283977	NA	NA	rs2555155-G	rs2555155	0	2555155	intron_variant	0	0.117	5e-06	5.30102999566398	(H19-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	5p15.32	5	4488132	RP11-44503.2	AC106799.2			ENSG00000248973	NA	NA	rs10462794-C	rs10462794	0	10462794	intron_variant	0	0.24	5e-06	5.30102999566398	(IGF2-DMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	11q13.1	11	65811201	OVOL1, CFL1	AP001266.1 - CFL1	ENSG00000255404	ENSG00000172757		13982	11821	rs11227306-A	rs11227306	0	11227306	regulatory_region_variant	1	0.38	2e-07	6.69897000433602	(IGF2-DMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	13q14.3	13	54059238	LINC00458	LINC00558 - LINC00458	ENSG00000261517	ENSG00000234787		119278	56545	rs9596905-A	rs9596905	0	9596905	intergenic_variant	1	0.06	2e-06	5.69897000433602	(IGF2-DMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	15q26.1	15	92263061	SLCO3A1, ST8SIA1	AC116903.2			ENSG00000260661	NA	NA	rs4304977-A	rs4304977	0	4304977	intron_variant	0	0.46	5e-06	5.30102999566398	(IGF2-DMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	22q13.32	22	48256185	intergenic	AL008720.1			ENSG00000285707	NA	NA	rs1004689-G	rs1004689	0	1004689	non_coding_transcript_exon_variant	0	0.467	2e-06	5.69897000433602	(IGF2-DMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	4q22.1	4	91494378	FAM190A	CCSER1			ENSG00000184305	NA	NA	rs11933531-A	rs11933531	0	11933531	intron_variant	0	0.04	3e-08	7.52287874528034	(KvDMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	11p15.4	11	5938527	TRIM5	TRIM5			ENSG00000132256	NA	NA	rs3858526-C	rs3858526	0	3858526	5_prime_UTR_variant	0	0.27	3e-06	5.52287874528034	(KvDMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	20q13.32	20	58833371	GNAS, GNAS-AS1	GNAS-AS1			ENSG00000235590	NA	NA	rs965808-G	rs965808	0	965808	intron_variant	0	0.22	5e-09	8.30102999566398	(NESPAS-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	8q22.1	8	96784503	PGCP	CPQ			ENSG00000104324	NA	NA	rs3763558-A	rs3763558	0	3763558	intron_variant	0	0.11	1e-06	6	(NESPAS-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	17q21.31	17	44960841	C1QL1	C1QL1			ENSG00000131094	NA	NA	rs1007190-T	rs1007190	0	1007190	intron_variant	0	0.13	2e-06	5.69897000433602	(IGF2-DMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	3p24.2	3	25880794	AC103588.1	LINC00692 - RPEP2	ENSG00000230891	ENSG00000234158		7046	134875	rs7644516-G	rs7644516	0	7644516	intergenic_variant	1	0.12	4e-06	5.39794000867204	(KvDMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	9q22.31	9	93800281	intergenic	PHF2 - AL442224.1	ENSG00000197724	ENSG00000231990		120694	8066	rs7027203-C	rs7027203	0	7027203	intergenic_variant	1	0.35	6e-06	5.22184874961636	(KvDMR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	4q32.1	4	160107665	intergenic	LINC02233 - AC093853.1	ENSG00000250488	ENSG00000250997		329837	414164	rs17261688-G	rs17261688	0	17261688	intergenic_variant	1	0.12	3e-06	5.52287874528034	(NESPAS-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	14q32.2	14	97057408	intergenic	AL049833.4 - AL049833.2	ENSG00000288034	ENSG00000259026		49784	53008	rs724210-C	rs724210	0	724210	intergenic_variant	1	0.33	8e-07	6.09691001300806	(NESPAS-ICR)	NA		Illumina [515966]	N
2013-12-03	23725790	Renteria ME	2013-06-03	Twin Res Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23725790	GWAS of DNA methylation variation within imprinting control regions suggests parent-of-origin association.	DNA methylation (variation)	256 European ancestry individuals	384 European ancestry individuals	2p21	2	43590366	THADA	THADA			ENSG00000115970	NA	NA	rs11897432-A	rs11897432	0	11897432	intron_variant	0	0.22	8e-07	6.09691001300806	(H19-ICR)	NA		Illumina [515966]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		3270	23176	rs495828-T	rs495828	0	495828	intergenic_variant	1	0.28	3e-12	11.5228787452803		0.091	[0.066-0.116] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	4q12	4	54528005	PDGFRA, HK1	AC098868.1 - LINC02260	ENSG00000251264	ENSG00000250456		81282	75206	rs218237-T	rs218237	0	218237	intergenic_variant	1	0.27	2e-17	16.698970004336		0.111	[0.086-0.136] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	6p21.1	6	41937537	BYSL, USP49, CCND3, MED20	CCND3			ENSG00000112576	NA	NA	rs3218097-T	rs3218097	0	3218097	intron_variant	0	0.19	1e-10	10		0.097	[0.068-0.126] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	2p21	2	46126027	PRKCE	PRKCE			ENSG00000171132	NA	NA	rs10495928-G	rs10495928	0	10495928	intron_variant	0	0.17	4e-08	7.39794000867204		0.087	[0.056-0.118] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	6q21	6	109313625	C6orf182, CD164	CCDC162P			ENSG00000203799	NA	NA	rs11966072-G	rs11966072	0	11966072	intron_variant	0	0.1	7e-09	8.15490195998574		0.114	[0.075-0.153] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	12p13.32	12	4224753	CCND2	AC007207.1 - CCND2-AS1	ENSG00000242444	ENSG00000255920		106621	23228	rs11611647-C	rs11611647	0	11611647	intergenic_variant	1	0.37	6e-09	8.22184874961636		0.071	[0.047-0.095] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-G	rs2736100	0	2736100	3_prime_UTR_variant	0	0.4	3e-08	7.52287874528034		0.067	[0.043-0.091] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Red blood cell count	14,392 Japanese ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.35	7e-48	47.1549019599857		0.179	[0.16-0.20] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	White blood cell count	14,677 Japanese ancestry individuals	NA	6p21.33	6	31117993	PSORS1C1, CDSN	CDSN, CDSN, CDSN, CDSN, CDSN, CDSN, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1, PSORS1C1			ENSG00000237114, ENSG00000137197, ENSG00000204539, ENSG00000237165, ENSG00000237123, ENSG00000206460, ENSG00000231094, ENSG00000233439, ENSG00000206458, ENSG00000233734, ENSG00000204540, ENSG00000235487	NA	NA	rs3094212-C	rs3094212	0	3094212	non_coding_transcript_exon_variant	0	0.35	7e-09	8.15490195998574		0.07	[0.046-0.094] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	White blood cell count	14,677 Japanese ancestry individuals	NA	17q21.1	17	39987295	CSF3, PSMD3, MED24, GSDMA	PSMD3			ENSG00000108344	NA	NA	rs4065321-T	rs4065321	0	4065321	intron_variant	0	0.32	3e-14	13.5228787452803		0.094	[0.070-0.118] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	White blood cell count	14,677 Japanese ancestry individuals	NA	6q23.3	6	135105435	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		2379	75873	rs4895441-G	rs4895441	0	4895441	regulatory_region_variant	1	0.37	2e-09	8.69897000433602		0.073	[0.049-0.097] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	White blood cell count	14,677 Japanese ancestry individuals	NA	12q15	12	68567804	RAP1B, NUP107, SLC35E3	RPSAP12 - Metazoa_SRP	ENSG00000240087	ENSG00000278569		13922	8054	rs12313946-C	rs12313946	0	12313946	intergenic_variant	1	0.47	3e-08	7.52287874528034		0.065	[0.041-0.089] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	White blood cell count	14,677 Japanese ancestry individuals	NA	7q21.2	7	92779056	CDK6	CDK6			ENSG00000105810	NA	NA	rs445-T	rs445	0	445	intron_variant	0	0.32	2e-08	7.69897000433602		0.07	[0.045-0.095] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	16q24.3	16	88787321	CDT1	PIEZO1 - CDT1	ENSG00000103335	ENSG00000167513		2101	16468	rs837763-C	rs837763	0	837763	intergenic_variant	1	0.38	4e-13	12.397940008672		0.088	[0.064-0.112] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.35	6e-12	11.2218487496164		0.085	[0.061-0.109] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-G	rs855791	0	855791	missense_variant	0	0.44	8e-14	13.0969100130081		0.089	[0.065-0.113] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	12q24.12	12	111803962	ALDH2	ALDH2			ENSG00000111275	NA	NA	rs671-A	rs671	0	671	missense_variant	0	0.26	7e-10	9.15490195998574		0.083	[0.058-0.108] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	5p15.33	5	1113129	SLC12A7	SLC12A7 - AC114291.1	ENSG00000113504	ENSG00000249201		1066	60012	rs4580814-T	rs4580814	0	4580814	regulatory_region_variant	1	0.26	5e-10	9.30102999566398		0.083	[0.058-0.108] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	9q34.2	9	133255935	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs8176746-T	rs8176746	0	8176746	missense_variant	0	0.18	4e-08	7.39794000867204		0.084	[0.055-0.113] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin concentration	14,377 Japanese ancestry individuals	NA	1q22	1	156285665	CCT3, BGLAP, PAQR6, SMG5, TMEM79, C1orf182, C1orf85, VHLL	TMEM79			ENSG00000163472	NA	NA	rs6684514-A	rs6684514	0	6684514	missense_variant	0	0.21	3e-09	8.52287874528034		0.086	[0.057-0.115] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Triglycerides	8,993 Japanese ancestry individuals	NA	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-C	rs1260326	0	1260326	missense_variant	0	0.45	1e-11	11		0.101	[0.072-0.13] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Triglycerides	8,993 Japanese ancestry individuals	NA	11q23.3	11	116715567	APOA1, APOC3, APOA4, APOA5	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		57272	32603	rs7350481-G	rs7350481	0	7350481	regulatory_region_variant	1	0.43	1e-49	49		0.241	[0.21-0.27] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Triglycerides	8,993 Japanese ancestry individuals	NA	1p31.3	1	62652525	ANGPTL3	DOCK7			ENSG00000116641	NA	NA	rs10889353-C	rs10889353	0	10889353	intron_variant	0	0.14	2e-09	8.69897000433602		0.126	[0.085-0.167] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Triglycerides	8,993 Japanese ancestry individuals	NA	8p21.3	8	19973410	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		6151	105704	rs10096633-T	rs10096633	0	10096633	regulatory_region_variant	1	0.12	9e-14	13.0457574905607		0.169	[0.12-0.21] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Triglycerides	8,993 Japanese ancestry individuals	NA	8q24.13	8	125478730	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs2954029-T	rs2954029	0	2954029	intron_variant	0	0.53	3e-07	6.52287874528034		0.076	[0.047-0.105] unit decrease	Illumina [561583]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	17q24.3	17	72588126	LOC100499467, SLC39A11, LINC00511	LINC00511			ENSG00000227036	NA	NA	rs718073-?	rs718073	0	718073	intron_variant	0	0.84	5e-06	5.30102999566398		0.35	[0.20-0.50] unit increase	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	17p13.1	17	10664166	MAGOH2, TMEM220, MYH3, C17orf48, SCO1	AC002347.1 - SCO1	ENSG00000261433	ENSG00000133028		5084	8308	rs169313-?	rs169313	0	169313	intergenic_variant	1	0.44	8e-06	5.09691001300806		0.25	[0.14-0.36] unit increase	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	15q26.3	15	101325267	VIMP, LOC100507472, PCSK6, CHSY1, SNRPA1	PCSK6			ENSG00000140479	NA	NA	rs7182874-T	rs7182874	0	7182874	intron_variant	0	0.71	9e-09	8.04575749056067		0.37	[0.24-0.50] unit decrease	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	1p12	1	118601809	intergenic	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126		337320	12524	rs10802047-?	rs10802047	0	10802047	intergenic_variant	1	0.38	2e-06	5.69897000433602		0.25	[0.15-0.36] unit decrease	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	3p25.2	3	11652993	VGLL4, ATG7	VGLL4			ENSG00000144560	NA	NA	rs4684792-?	rs4684792	0	4684792	intron_variant	0	0.18	9e-06	5.04575749056067		0.28	[0.16-0.4] unit decrease	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	7p22.1	7	5485174	FBXL18, TNRC18, ACTB, MIR589	FBXL18			ENSG00000155034	NA	NA	rs10216189-?	rs10216189	0	10216189	intron_variant	0	0.39	4e-06	5.39794000867204		0.24	[0.14-0.34] unit decrease	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	11p13	11	35473893	PAMR1, SLC1A2	PAMR1			ENSG00000149090	NA	NA	rs1996369-?	rs1996369	0	1996369	intron_variant	0	0.21	9e-06	5.04575749056067		0.27	[0.15-0.39] unit increase	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	14q11.2	14	22487722	DAD1	TRAJ51 - TRAJ50	ENSG00000248366	ENSG00000211839		477	871	rs227869-?	rs227869	0	227869	regulatory_region_variant	1	0.32	4e-06	5.39794000867204		0.25	[0.14-0.36] unit decrease	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	15q21.3	15	56444280	TEX9, MNS1	TEX9, MNS1			ENSG00000151575, ENSG00000138587	NA	NA	rs6493858-?	rs6493858	0	6493858	intron_variant	0	0.41	4e-06	5.39794000867204		0.25	[0.14-0.35] unit increase	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill in reading disability	728 European ancestry individuals with reading disability	NA	16q21	16	62764948	intergenic	AC009110.1 - AC010546.1	ENSG00000231589	ENSG00000260332		166499	43274	rs2962462-?	rs2962462	0	2962462	intergenic_variant	1	0.56	2e-06	5.69897000433602		0.29	[0.17-0.41] unit increase	Illumina [2095209]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill	2,666 European ancestry individuals	NA	Xq26.2	X	133991764	GPC3	AF003529.1 - Y_RNA	ENSG00000232068	ENSG00000265852		1678	150464	rs7883190-?	rs7883190	0	7883190	intergenic_variant	1	0.62	2e-06	5.69897000433602		0.12	[0.071-0.169] unit increase	Illumina [NR]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill	2,666 European ancestry individuals	NA	20p12.2	20	11228874	LOC339593	C20orf187 - AL049649.1	ENSG00000125899	ENSG00000230990		199419	5296	rs6040449-?	rs6040449	0	6040449	regulatory_region_variant	1	0.63	4e-06	5.39794000867204		0.14	[0.081-0.199] unit increase	Illumina [NR]	N
2014-04-02	24068947	Brandler WM	2013-09-12	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068947	Common variants in left/right asymmetry genes and pathways are associated with relative hand skill.	Relative hand skill	2,666 European ancestry individuals	NA	20q13.2	20	54794480	intergenic	DOK5 - RNU4ATAC7P	ENSG00000101134	ENSG00000252089		143311	65208	rs13037755-?	rs13037755	0	13037755	intergenic_variant	1	0.71	5e-06	5.30102999566398		0.26	[0.15-0.37] unit increase	Illumina [NR]	N
2013-09-14	23612905	Zhao SX	2013-04-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23612905	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	Graves' disease	1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls	7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls	8q24.22	8	133133268	SLA, WISP1, TG	TG			ENSG00000042832	NA	NA	rs2294025-T	rs2294025	0	2294025	intron_variant	0	0.19	8e-09	8.09691001300806		1.16	[1.10-1.22]	Illumina [8019905] (imputed)	N
2013-09-14	23612905	Zhao SX	2013-04-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23612905	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	Graves' disease	1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls	7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls	14q32.2	14	98021670	intergenic	LINC01550 - AL163932.1	ENSG00000246223	ENSG00000259097		43546	46491	rs1456988-?	rs1456988	0	1456988	intergenic_variant	1	0.53	5e-09	8.30102999566398		1.12	[1.09-1.18]	Illumina [8019905] (imputed)	N
2013-09-14	23612905	Zhao SX	2013-04-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23612905	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	Graves' disease	1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls	7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls	22q12.3	22	37185445	C1QTNF6, RAC2	C1QTNF6			ENSG00000133466	NA	NA	rs229527-?	rs229527	0	229527	missense_variant	0	0.71	5e-20	19.301029995664		1.23	[1.19-1.3]	Illumina [8019905] (imputed)	N
2013-09-14	23612905	Zhao SX	2013-04-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23612905	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	Graves' disease	1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls	7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls	Xq21.1	X	79241621	ITM2A, GPR174	CTHRC1P1 - KIF4CP	ENSG00000271005	ENSG00000225025		63953	81825	rs5912838-?	rs5912838	0	5912838	intergenic_variant	1	0.58	2e-33	32.698970004336		1.32	[1.25-1.37]	Illumina [8019905] (imputed)	N
2013-09-14	23612905	Zhao SX	2013-04-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23612905	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	Graves' disease	1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls	7,891 Han Chinese ancestry cases, 8,351 Han Chinese ancestry controls	1q23.2	1	160495121	SLAMF6	SLAMF6			ENSG00000162739	NA	NA	rs1265883-C	rs1265883	0	1265883	intron_variant	0	0.1	2e-18	17.698970004336		1.34	[1.25-1.43]	Illumina [8019905] (imputed)	N
2013-09-14	23612905	Zhao SX	2013-04-29	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/23612905	Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.	Graves' disease	1,442 Han Chinese ancestry cases, 1,468 Han Chinese ancestry controls	6,358 Han Chinese ancestry cases, 6,722 Han Chinese ancestry controls	9q34.2	9	133273813	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs505922-?	rs505922	0	505922	intron_variant	0	0.53	2e-10	9.69897000433602		1.14	[1.1-1.19]	Illumina [483947]	N
2012-06-20	22538805	Tantisira KG	2012-04-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22538805	Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.	Asthma	418 European ancestry cases	407 European ancestry cases	6q27	6	166121254	T	AL627443.1 - TBXT	ENSG00000231297	ENSG00000164458		7981	36402	rs6456042-?	rs6456042	0	6456042	intergenic_variant	1	NR	6e-06	5.22184874961636		NA		Affymetrix [444088]	N
2013-06-28	23467860	Pare G	2013-03-06	Circulation	www.ncbi.nlm.nih.gov/pubmed/23467860	Genetic determinants of dabigatran plasma levels and their relation to bleeding.	Response to dabigatran etexilate treatment	1,490 European ancestry atrial fibrillation cases at risk of stroke	204 European ancestry atrial fibrillation cases at risk of stroke, 66 Latin American atrial fibrillation cases at risk of stroke, 1 Arab ancestry atrial fibrillation cases at risk of stroke, 5 Black African atrial fibrillation cases at risk of stroke, 25 East Asian ancestry atrial fibrillation cases at risk of stroke, 1 Colored African atrial fibrillation cases at risk of stroke, 9 South Asian ancestry atrial fibrillation cases at risk of stroke, 15 Asian ancestry atrial fibrillation cases at risk of stroke, 134 atrial fibrillation cases at risk of stroke	16q12.2	16	55810697	CES1	CES1, CES1			ENSG00000198848, ENSG00000262243	NA	NA	rs2244613-?	rs2244613	0	2244613	intron_variant	0	0.82	5e-07	6.30102999566398	(Trough concentrations)	1.16	[1.10-1.22]	Illumina [551203]	N
2013-06-28	23467860	Pare G	2013-03-06	Circulation	www.ncbi.nlm.nih.gov/pubmed/23467860	Genetic determinants of dabigatran plasma levels and their relation to bleeding.	Response to dabigatran etexilate treatment	1,490 European ancestry atrial fibrillation cases at risk of stroke	204 European ancestry atrial fibrillation cases at risk of stroke, 66 Latin American atrial fibrillation cases at risk of stroke, 1 Arab ancestry atrial fibrillation cases at risk of stroke, 5 Black African atrial fibrillation cases at risk of stroke, 25 East Asian ancestry atrial fibrillation cases at risk of stroke, 1 Colored African atrial fibrillation cases at risk of stroke, 9 South Asian ancestry atrial fibrillation cases at risk of stroke, 15 Asian ancestry atrial fibrillation cases at risk of stroke, 134 atrial fibrillation cases at risk of stroke	16q12.2	16	55827882	CES1	CES1, CES1			ENSG00000198848, ENSG00000262243	NA	NA	rs8192935-?	rs8192935	0	8192935	splice_region_variant	0	0.67	1e-06	6	(Peak concentrations)	1.12	[1.08-1.18]	Illumina [551203]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Urate levels	8,868 Japanese ancestry individuals	NA	4p16.1	4	9914117	SLC2A9	SLC2A9			ENSG00000109667	NA	NA	rs11722228-T	rs11722228	0	11722228	intron_variant	0	0.45	7e-24	23.1549019599857		0.164	[0.13-0.2] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Urate levels	8,868 Japanese ancestry individuals	NA	11q13.1	11	64673448	SLC22A12	NRXN2			ENSG00000110076	NA	NA	rs506338-C	rs506338	0	506338	intron_variant	0	0.17	2e-31	30.698970004336		0.229	[0.19-0.27] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Urate levels	8,868 Japanese ancestry individuals	NA	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-T	rs780094	0	780094	intron_variant	0	0.57	5e-06	5.30102999566398		0.069	[0.040,0.098] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	11q23.3	11	116715567	APOA1, APOC3, APOA4, APOA5	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		57272	32603	rs7350481-T	rs7350481	0	7350481	regulatory_region_variant	1	0.28	9e-10	9.04575749056067	(HDL)	0.124	[0.085-0.163] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-A	rs3764261	0	3764261	regulatory_region_variant	1	0.21	5e-29	28.301029995664	(HDL)	0.254	[0.21-0.3] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	2p23.3	2	27508073	GCKR	GCKR			ENSG00000084734	NA	NA	rs1260326-C	rs1260326	0	1260326	missense_variant	0	0.44	4e-09	8.39794000867204	(ALB)	0.085	[0.056-0.114] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	8p21.3	8	19986711	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		19452	92403	rs12678919-G	rs12678919	0	12678919	intergenic_variant	1	0.18	9e-06	5.04575749056067	(HDL)	0.125	[0.070-0.180] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.35	1e-10	10	(Ht)	0.08	[0.056-0.104] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		3270	23176	rs495828-T	rs495828	0	495828	intergenic_variant	1	0.28	6e-10	9.22184874961636	(Ht)	0.081	[0.056-0.106] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	22q12.3	22	37074184	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs2413450-T	rs2413450	0	2413450	intron_variant	0	0.59	5e-06	5.30102999566398	(Ht)	0.204	[0.116-0.291] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	15q21.3	15	53648110	WDR72	WDR72			ENSG00000166415	NA	NA	rs10518733-C	rs10518733	0	10518733	intron_variant	0	0.4	2e-08	7.69897000433602	(sCr)	0.068	[0.044-0.092] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	17p11.2	17	16945825	TNFRSF13B	TNFRSF13B			ENSG00000240505	NA	NA	rs4273077-G	rs4273077	0	4273077	intron_variant	0	0.46	3e-10	9.52287874528034	(TP)	0.088	[0.061-0.115] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	19q13.33	19	49496752	FCGRT, RPL13A, RPS11, RCN3	RPS11			ENSG00000142534	NA	NA	rs2280401-A	rs2280401	0	2280401	intron_variant	0	0.16	3e-08	7.52287874528034	(TP)	0.107	[0.07-0.144] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		3270	23176	rs495828-T	rs495828	0	495828	intergenic_variant	1	0.28	4e-59	58.397940008672	(ALP)	0.308	[0.27-0.35] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	15q26.2	15	94727238	intergenic	AC022308.1 - AC087633.2	ENSG00000286917	ENSG00000277654		719	113821	rs7173947-C	rs7173947	0	7173947	intergenic_variant	1	0.29	3e-08	7.52287874528034	(ALP)	0.105	[0.068-0.142] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	1p36.12	1	21578036	ALPL	ALPL			ENSG00000162551	NA	NA	rs2242420-T	rs2242420	0	2242420	3_prime_UTR_variant	0	0.18	5e-13	12.301029995664	(ALP)	0.163	[0.12-0.21] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	6p22.3	6	24480067	GPLD1	GPLD1			ENSG00000112293	NA	NA	rs6911965-C	rs6911965	0	6911965	intron_variant	0	0.66	2e-11	10.698970004336	(ALP)	0.235	[0.17-0.3] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	22q13.31	22	43937814	PARVB, PNPLA3, SAMM50	PNPLA3			ENSG00000100344	NA	NA	rs2896019-G	rs2896019	0	2896019	intron_variant	0	0.45	2e-12	11.698970004336	(ALT)	0.085	[0.061-0.109] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	12q24.12	12	111672685	BRAP, ALDH2	BRAP			ENSG00000089234	NA	NA	rs3782886-G	rs3782886	0	3782886	synonymous_variant	0	0.27	5e-09	8.30102999566398	(ALT)	0.079	[0.052-0.106] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	10p12.33	10	17833817	FAM23A, MRC1L1, FAM23B, MRC1	MRC1			ENSG00000260314	NA	NA	rs2477664-T	rs2477664	0	2477664	synonymous_variant	0	0.44	1e-16	16	(AST)	0.099	[0.075-0.123] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	22q13.31	22	43937814	PARVB, PNPLA3, SAMM50	PNPLA3			ENSG00000100344	NA	NA	rs2896019-G	rs2896019	0	2896019	intron_variant	0	0.45	2e-12	11.698970004336	(AST)	0.085	[0.061-0.109] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	3q27.3	3	187969286	intergenic	LINC01991			ENSG00000224187	NA	NA	rs9820070-C	rs9820070	0	9820070	intron_variant	0	0.31	1e-11	11	(BUN)	0.087	[0.062-0.112] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	18q12.3	18	45651657	SLC14A2	AC023421.2, SLC14A2			ENSG00000267193, ENSG00000132874	NA	NA	rs4890568-G	rs4890568	0	4890568	intron_variant	0	0.24	2e-10	9.69897000433602	(BUN)	0.087	[0.06-0.114] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	3p14.1	3	66772733	intergenic	RPL21P41 - AC098969.2	ENSG00000214560	ENSG00000288039		135321	7343	rs11709625-A	rs11709625	0	11709625	intergenic_variant	1	0.17	1e-10	10	(BUN)	0.102	[0.071-0.133] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	12p13.31	12	7538538	CD163	CD163 - GAPDHP31	ENSG00000177575	ENSG00000235868		34645	27831	rs7136716-G	rs7136716	0	7136716	regulatory_region_variant	1	0.39	3e-26	25.5228787452803	(CK)	0.165	[0.13-0.2] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Triglycerides	8,993 Japanese ancestry individuals	NA	7q11.23	7	73450539	MIXIPL	BAZ1B			ENSG00000009954	NA	NA	rs714052-G	rs714052	0	714052	intron_variant	0	0.11	3e-07	6.52287874528034		0.123	[0.076-0.170] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	9p24.1	9	4763176	AK3	AL353151.2 - ECM1P1	ENSG00000287759	ENSG00000270639		3537	5441	rs385893-C	rs385893	0	385893	regulatory_region_variant	1	0.76	3e-13	12.5228787452803		5.928	[4.344-7.507] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.34	3e-14	13.5228787452803		0.093	[0.069-0.117] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	3q27.1	3	184372478	THPO, CHRD	THPO			ENSG00000090534	NA	NA	rs6141-T	rs6141	0	6141	3_prime_UTR_variant	0	0.45	5e-11	10.301029995664		0.076	[0.052-0.100] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	6p21.31	6	33580617	BAK1	GGNBP1			ENSG00000204188	NA	NA	rs5745568-T	rs5745568	0	5745568	intron_variant	0	0.23	7e-11	10.1549019599857		0.09	[0.063-0.117] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	9p24.1	9	4763176	RCL1	AL353151.2 - ECM1P1	ENSG00000287759	ENSG00000270639		3537	5441	rs385893-T	rs385893	0	385893	regulatory_region_variant	1	0.25	3e-13	12.5228787452803		0.099	[0.072-0.126] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	12q24.12	12	111449855	SH2B3	ATXN2, SH2B3			ENSG00000204842, ENSG00000111252	NA	NA	rs739496-A	rs739496	0	739496	3_prime_UTR_variant	0	0.16	5e-19	18.301029995664		0.141	[0.11-0.17] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Platelet count	14,806 Japanese ancestry individuals	NA	17p13.2	17	4933086	GP1BA	GP1BA, CHRNE			ENSG00000185245, ENSG00000108556	NA	NA	rs6065-T	rs6065	0	6065	missense_variant	0	0.12	2e-12	11.698970004336		0.124	[0.089-0.159] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	16p13.3	16	175654	RGS11, ITFG3, HBA2, HBA1, LUC7L	HBA2 - HBA1	ENSG00000188536	ENSG00000206172		1944	1026	rs2858942-A	rs2858942	0	2858942	intergenic_variant	1	0.46	3e-09	8.52287874528034		0.069	[0.045-0.093] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.35	3e-66	65.5228787452803		0.211	[0.19-0.23] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	9p24.1	9	4844265	RCL1	RCL1			ENSG00000120158	NA	NA	rs2236496-C	rs2236496	0	2236496	intron_variant	0	0.47	6e-11	10.2218487496164		0.077	[0.053-0.101] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	3q29	3	196180782	TFRC, ZDHHC19	LINC00885 - ZDHHC19	ENSG00000224652	ENSG00000163958		19889	16670	rs4916483-C	rs4916483	0	4916483	intergenic_variant	1	0.44	4e-11	10.397940008672		0.078	[0.054-0.102] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-G	rs855791	0	855791	missense_variant	0	0.44	5e-25	24.301029995664		0.122	[0.098-0.146] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	6q24.1	6	139512875	CITED2	AL592429.2			ENSG00000226571	NA	NA	rs632057-G	rs632057	0	632057	intron_variant	0	0.25	1e-09	9		0.081	[0.056-0.106] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	15q22.31	15	65759007	IGDCC4, DPP8, PTPLAD1, C15orf44, SLC24A1, DENND4A	RAB11A, DENND4A			ENSG00000103769, ENSG00000174485	NA	NA	rs6494537-C	rs6494537	0	6494537	intron_variant	0	0.27	3e-09	8.52287874528034		0.078	[0.053-0.103] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	22q13.33	22	50528485	TYMP, KLHDC7B, SCO2, NCAPH2	TYMP			ENSG00000025708	NA	NA	rs470119-T	rs470119	0	470119	non_coding_transcript_exon_variant	0	0.26	4e-08	7.39794000867204		0.074	[0.049-0.099] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	4q12	4	54528005	PDGFRA, HK1	AC098868.1 - LINC02260	ENSG00000251264	ENSG00000250456		81282	75206	rs218237-T	rs218237	0	218237	intergenic_variant	1	0.27	3e-25	24.5228787452803		0.136	[0.11-0.16] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	3p24.2	3	24309320	THRB	THRB			ENSG00000151090	NA	NA	rs9310736-A	rs9310736	0	9310736	intron_variant	0	0.26	4e-10	9.39794000867204		0.084	[0.059-0.109] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	1q31.3	1	198626376	ATP6V1G3, PTPRC	AL157402.1 - PTPRC	ENSG00000223881	ENSG00000081237		27508	12081	rs12127588-A	rs12127588	0	12127588	intergenic_variant	1	0.21	7e-10	9.15490195998574		0.09	[0.061-0.119] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	6p21.1	6	41937537	BYSL, USP49, CCND3, MED20	CCND3			ENSG00000112576	NA	NA	rs3218097-A	rs3218097	0	3218097	intron_variant	0	0.19	2e-20	19.698970004336		0.139	[0.11-0.17] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	10q11.22	10	46002468	MSMB, NCOA4, TIMM23	TIMM23			ENSG00000265354	NA	NA	rs7085433-A	rs7085433	0	7085433	intron_variant	0	0.15	6e-10	9.22184874961636		0.102	[0.071-0.133] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	10q11.21	10	45459616	ANUBL1, FAM21C, AGAP4, MARCH8, ALOX5	MARCH8			ENSG00000165406	NA	NA	rs2279434-T	rs2279434	0	2279434	intron_variant	0	0.12	4e-12	11.397940008672		0.128	[0.093-0.163] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular hemoglobin	Up to 14,362 Japanese ancestry individuals	NA	6q21	6	109313625	C6orf182, CD164	CCDC162P			ENSG00000203799	NA	NA	rs11966072-G	rs11966072	0	11966072	intron_variant	0	0.1	1e-08	8		0.111	[0.072-0.15] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Urate levels	8,868 Japanese ancestry individuals	NA	2q31.1	2	169348336	LRP2	LRP2			ENSG00000081479	NA	NA	rs2544390-C	rs2544390	0	2544390	intron_variant	0	0.49	4e-08	7.39794000867204		0.082	[0.053-0.111] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Urate levels	8,868 Japanese ancestry individuals	NA	4q22.1	4	88133515	ABCG2	ABCG2			ENSG00000118777	NA	NA	rs4148155-G	rs4148155	0	4148155	intron_variant	0	0.3	1e-13	13		0.121	[0.09-0.152] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	22q11.23	22	24600663	GGT1	GGT1, GGT1			ENSG00000286070, ENSG00000100031	NA	NA	rs5751902-T	rs5751902	0	5751902	intron_variant	0	0.37	8e-20	19.0969100130081	(GGT)	0.172	[0.13-0.21] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	12q24.12	12	111803962	ALDH2	ALDH2			ENSG00000111275	NA	NA	rs671-A	rs671	0	671	missense_variant	0	0.26	5e-09	8.30102999566398	(GGT)	0.123	[0.082-0.164] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	22q12.3	22	37071230	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs5756504-T	rs5756504	0	5756504	intron_variant	0	0.45	2e-10	9.69897000433602	(Hb)	0.076	[0.052-0.1] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	9q34.2	9	133279294	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		3270	23176	rs495828-T	rs495828	0	495828	intergenic_variant	1	0.28	1e-11	11	(Hb)	0.089	[0.064-0.114] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	2p21	2	46126027	PRKCE	PRKCE			ENSG00000171132	NA	NA	rs10495928-A	rs10495928	0	10495928	intron_variant	0	0.83	5e-06	5.30102999566398	(Hb)	0.032	[0.018-0.046] unit increase	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	15q21.3	15	58431280	LIPC	LIPC, ALDH1A2			ENSG00000166035, ENSG00000128918	NA	NA	rs1077834-T	rs1077834	0	1077834	intron_variant	0	0.49	1e-14	14	(HDL)	0.14	[0.1-0.18] unit decrease	Illumina [561583]	N
2013-11-05	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Hematological and biochemical traits	Up to 14,402 Japanese individuals	NA	2p21	2	46133768	PRKCE	PRKCE			ENSG00000171132	NA	NA	rs10168349-G	rs10168349	0	10168349	intron_variant	0	0.83	5e-07	6.30102999566398	(Ht)	0.317	[0.193-0.44] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	6q23.3	6	135097497	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7775698-T	rs7775698	0	7775698	intron_variant	0	0.35	3e-56	55.5228787452803		0.194	[0.17-0.22] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	22q11.21	22	21610472	UBE2L3, HIC2	UBE2L3			ENSG00000185651	NA	NA	rs4821112-A	rs4821112	0	4821112	intron_variant	0	0.47	1e-08	8		0.067	[0.043-0.091] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	20q13.31	20	57416639	RBM38	RBM38 - AL109955.2	ENSG00000132819	ENSG00000286052		7306	26103	rs6092477-G	rs6092477	0	6092477	regulatory_region_variant	1	0.42	1e-08	8		0.068	[0.044-0.092] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	9p24.1	9	4844265	RCL1	RCL1			ENSG00000120158	NA	NA	rs2236496-C	rs2236496	0	2236496	intron_variant	0	0.47	3e-14	13.5228787452803		0.09	[0.066-0.114] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	3q29	3	196180782	TFRC, ZDHHC19	LINC00885 - ZDHHC19	ENSG00000224652	ENSG00000163958		19889	16670	rs4916483-C	rs4916483	0	4916483	intergenic_variant	1	0.44	2e-08	7.69897000433602		0.067	[0.043-0.091] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-G	rs855791	0	855791	missense_variant	0	0.44	1e-15	15		0.095	[0.071-0.119] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	6q24.1	6	139512875	CITED2	AL592429.2			ENSG00000226571	NA	NA	rs632057-G	rs632057	0	632057	intron_variant	0	0.25	1e-09	9		0.082	[0.057-0.107] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	8p21.3	8	21963302	DOK2, XPO7	XPO7			ENSG00000130227	NA	NA	rs7843479-A	rs7843479	0	7843479	intron_variant	0	0.29	3e-08	7.52287874528034		0.072	[0.047-0.097] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	4q12	4	54528005	PDGFRA, HK1	AC098868.1 - LINC02260	ENSG00000251264	ENSG00000250456		81282	75206	rs218237-T	rs218237	0	218237	intergenic_variant	1	0.27	2e-29	28.698970004336		0.147	[0.12-0.17] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	3p24.2	3	24309320	THRB	THRB			ENSG00000151090	NA	NA	rs9310736-A	rs9310736	0	9310736	intron_variant	0	0.26	3e-08	7.52287874528034		0.074	[0.049-0.099] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	6p21.1	6	41937537	BYSL, USP49, CCND3, MED20	CCND3			ENSG00000112576	NA	NA	rs3218097-A	rs3218097	0	3218097	intron_variant	0	0.19	4e-27	26.397940008672		0.162	[0.13-0.19] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	10q11.22	10	46002468	MSMB, NCOA4, TIMM23	TIMM23			ENSG00000265354	NA	NA	rs7085433-A	rs7085433	0	7085433	intron_variant	0	0.15	7e-09	8.15490195998574		0.095	[0.064-0.126] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	1q44	1	247882970	TRIM58	TRIM58 - OR2W3	ENSG00000162722	ENSG00000238243		2832	12617	rs11204538-C	rs11204538	0	11204538	intergenic_variant	1	0.16	2e-08	7.69897000433602		0.091	[0.060-0.122] unit decrease	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	10q11.21	10	45459616	ANUBL1, FAM21C, AGAP4, MARCH8, ALOX5	MARCH8			ENSG00000165406	NA	NA	rs2279434-T	rs2279434	0	2279434	intron_variant	0	0.12	3e-11	10.5228787452803		0.123	[0.088-0.158] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	6q21	6	109313625	C6orf182, CD164	CCDC162P			ENSG00000203799	NA	NA	rs11966072-G	rs11966072	0	11966072	intron_variant	0	0.1	3e-08	7.52287874528034		0.11	[0.071-0.149] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	6p22.2	6	26107235	HFE	HIST1H4C - HIST1H1T	ENSG00000197061	ENSG00000187475		2925	184	rs198846-A	rs198846	0	198846	intergenic_variant	1	0.06	2e-06	5.69897000433602		0.679	[0.402-0.956] unit increase	Illumina [561583]	N
2013-09-04	20139978	Kamatani Y	2010-02-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20139978	Genome-wide association study of hematological and biochemical traits in a Japanese population.	Mean corpuscular volume	14,364 Japanese ancestry individuals	NA	4q12	4	54541595	KIT	AC098868.1 - LINC02260	ENSG00000251264	ENSG00000250456		94872	61616	rs172629-C	rs172629	0	172629	intergenic_variant	1	0.74	1e-27	27		0.698	[0.573-0.824] unit decrease	Illumina [561583]	N
2011-07-13	21700618	Nan H	2011-06-23	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21700618	Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma.	Basal cell carcinoma	2,045 European ancestry cases, 6,013 European ancestry controls	1,426 cases, 4,845 controls	16q24.3	16	89919709	MC1R	MC1R, AC092143.1			ENSG00000258839, ENSG00000198211	NA	NA	rs1805007-T	rs1805007	0	1805007	missense_variant	0	0.07	4e-17	16.397940008672		1.55	[1.45-1.66]	Affymetrix, Illumina [2318094] (imputed)	N
2011-07-13	21700618	Nan H	2011-06-23	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21700618	Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma.	Basal cell carcinoma	2,045 European ancestry cases, 6,013 European ancestry controls	1,426 cases, 4,845 controls	6p25.3	6	475489	EXOC2	AL512308.1			ENSG00000286364	NA	NA	rs12210050-T	rs12210050	0	12210050	non_coding_transcript_exon_variant	0	0.17	1e-09	9		1.24	[1.17-1.31]	Affymetrix, Illumina [2318094] (imputed)	N
2011-07-13	21700618	Nan H	2011-06-23	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21700618	Genome-wide association study identifies novel alleles associated with risk of cutaneous basal cell carcinoma and squamous cell carcinoma.	Basal cell carcinoma	2,045 European ancestry cases, 6,013 European ancestry controls	1,426 cases, 4,845 controls	13q32.3	13	99389484	UBAC2	UBAC2 - CCR12P	ENSG00000134882	ENSG00000238241		2980	15200	rs7335046-G	rs7335046	0	7335046	intergenic_variant	1	0.12	3e-08	7.52287874528034		1.26	[1.18-1.34]	Affymetrix, Illumina [2318094] (imputed)	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	8q12.3	8	62971034	NKAIN3	NKAIN3			ENSG00000185942	NA	NA	rs7834588-T	rs7834588	0	7834588	intron_variant	0	0.41	6e-07	6.22184874961636	(alpha-TOH)	0.03	[0.010-0.050] mg/L increase	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	12p13.31	12	6829708	CD4, LEPREL2, GNB3	P3H3, GPR162			ENSG00000110811, ENSG00000250510	NA	NA	rs3741920-T	rs3741920	0	3741920	non_coding_transcript_exon_variant	0	0.16	4e-06	5.39794000867204	(alpha-TOH)	0.04	[0.020-0.060] mg/L decrease	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	11q23.3	11	116778201	ZNF259, LOC100128347, APOA5, SIK3, BUD13	ZPR1			ENSG00000109917	NA	NA	rs964184-G	rs964184	0	964184	3_prime_UTR_variant	0	0.15	3e-12	11.5228787452803	(alpha-TOH)	0.07	[0.050-0.090] mg/L increase	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	19p13.12	19	15879621	CYP4F2, LOC729645	CYP4F2			ENSG00000186115	NA	NA	rs2108622-T	rs2108622	0	2108622	missense_variant	0	0.19	2e-07	6.69897000433602	(alpha-TOH)	0.04	[0.020-0.060] mg/L increase	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	11q23.3	11	116778201	ZNF259, BUD13	ZPR1			ENSG00000109917	NA	NA	rs964184-G	rs964184	0	964184	3_prime_UTR_variant	0	0.15	4e-07	6.39794000867204	(change in alpha-TOH)	0.88	[0.55-1.21] unit increase	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	11p13	11	35134185	CD44	AL356215.1			ENSG00000255521	NA	NA	rs2785173-T	rs2785173	0	2785173	intron_variant	0	0.02	3e-06	5.52287874528034	(change in alpha-TOH)	1.94	[1.12-2.76] unit increase	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	7q34	7	140892427	BRAF	BRAF			ENSG00000157764	NA	NA	rs17623382-G	rs17623382	0	17623382	intron_variant	0	0.16	4e-06	5.39794000867204	(change in alpha-TOH)	0.78	[0.45-1.11] unit increase	Illumina [549989]	N
2012-06-18	22437554	Major JM	2012-03-21	J Nutr	www.ncbi.nlm.nih.gov/pubmed/22437554	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	Response to Vitamin E supplementation	2,112 European ancestry individuals	NA	3p25.3	3	11033328	SLC6A1	SLC6A1			ENSG00000157103	NA	NA	rs2675163-C	rs2675163	0	2675163	non_coding_transcript_exon_variant	0	0.23	6e-06	5.22184874961636	(change in alpha-TOH)	0.68	[0.39-0.97] unit increase	Illumina [549989]	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	3q21.1	3	122284910	CASR	CASR			ENSG00000036828	NA	NA	rs1801725-T	rs1801725	0	1801725	missense_variant	0	0.15	9e-86	85.0457574905607		0.071	[0.063-0.079] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	2q37.1	2	233356202	DGKD	DGKD, DGKD			ENSG00000280873, ENSG00000077044	NA	NA	rs1550532-C	rs1550532	0	1550532	intron_variant	0	0.31	8e-11	10.0969100130081		0.018	[0.012-0.024] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-T	rs780094	0	780094	intron_variant	0	0.42	1e-10	10		0.017	[0.016-0.018] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	10p14	10	9286688	GATA3	LINC00709			ENSG00000230014	NA	NA	rs10491003-T	rs10491003	0	10491003	non_coding_transcript_exon_variant	0	0.09	5e-09	8.30102999566398		0.027	[0.017-0.037] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	11p15.4	11	3007859	CARS	CARS, CARS			ENSG00000278191, ENSG00000110619	NA	NA	rs7481584-A	rs7481584	0	7481584	non_coding_transcript_exon_variant	0	0.3	1e-10	10		0.018	[0.012-0.024] unit decrease	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	13q14.11	13	41984940	KIAA0564, DGKH	VWA8-AS1 - RPS28P8	ENSG00000278338	ENSG00000226093		3375	18490	rs7336933-A	rs7336933	0	7336933	intergenic_variant	1	0.15	9e-10	9.04575749056067		0.022	[0.014-0.03] unit decrease	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	20q13.2	20	54157888	CYP24A1	CYP24A1			ENSG00000019186	NA	NA	rs1570669-A	rs1570669	0	1570669	intron_variant	0	0.66	9e-12	11.0457574905607		0.018	[0.012-0.024] unit decrease	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	5q35.3	5	177370342	RGS14, SLC34A1	RGS14			ENSG00000169220	NA	NA	rs4074995-A	rs4074995	0	4074995	intron_variant	0	0.28	5e-06	5.30102999566398		0.013	[0.0071-0.0189] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	6q13	6	73749014	CD109	CD109			ENSG00000156535	NA	NA	rs9447004-A	rs9447004	0	9447004	intron_variant	0	0.48	3e-06	5.52287874528034		0.012	[0.0061-0.0179] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	6q25.3	6	156807123	ARID1B	ARID1B			ENSG00000049618	NA	NA	rs11967485-A	rs11967485	0	11967485	intron_variant	0	0.1	9e-07	6.04575749056067		0.026	[0.016-0.036] unit decrease	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	7q11.21	7	65806210	VKORC1L1	GTF2IP5 - RNU6-912P	ENSG00000224316	ENSG00000200670		4143	8462	rs17711722-T	rs17711722	0	17711722	intergenic_variant	1	0.47	8e-09	8.09691001300806		0.015	[0.0091-0.0209] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	17p13.3	17	1730810	SERPINF2, WDR81	WDR81, WDR81, AC130343.1			ENSG00000276021, ENSG00000167716, ENSG00000262791	NA	NA	rs12150338-T	rs12150338	0	12150338	synonymous_variant	0	0.09	2e-06	5.69897000433602		0.03	[0.018-0.042] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2014-03-27	24068962	O'Seaghdha CM	2013-09-19	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/24068962	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	Calcium levels	39,400 European ancestry individuals	Up to 21,679 European ancestry individuals	20p11.21	20	25259553	PYGB	PYGB			ENSG00000100994	NA	NA	rs2281558-T	rs2281558	0	2281558	intron_variant	0	0.25	5e-06	5.30102999566398		0.015	[0.0091-0.0209] unit increase	Affymetrix, Illumina [2500000] (imputed)	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	6q14.3	6	86756774	NR	AL353133.1 - AL353133.2	ENSG00000218561	ENSG00000219190		26666	11748	rs493187-?	rs493187	0	493187	TF_binding_site_variant	1	NR	3e-06	5.52287874528034		1.2298	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q33.2	13	105999312	DAOA	AL138701.2			ENSG00000287923	NA	NA	rs4996815-?	rs4996815	0	4996815	intron_variant	0	NR	1e-07	7		1.2764	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xq27.1	X	140084524	NR	HNRNPA3P3 - RN7SL727P	ENSG00000214653	ENSG00000241248		51044	1331	rs5907577-?	rs5907577	0	5907577	intergenic_variant	1	NR	5e-06	5.30102999566398		1.2743	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xq27.1	X	140231900	NR	FO393408.1 - AL137014.1	ENSG00000231110	ENSG00000224942		15096	165162	rs5955415-?	rs5955415	0	5955415	intergenic_variant	1	NR	2e-06	5.69897000433602		1.4612	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	20p11.23	20	19871859	RIN2	RIN2			ENSG00000132669	NA	NA	rs6046396-?	rs6046396	0	6046396	non_coding_transcript_exon_variant	0	NR	4e-07	6.39794000867204		1.2815	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q14.3	13	53861102	NR	LINC00558			ENSG00000261517	NA	NA	rs6561750-?	rs6561750	0	6561750	intron_variant	0	NR	9e-06	5.04575749056067		1.2266	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8q24.3	8	141349451	NR	LINC01300 - AC100803.3	ENSG00000253595	ENSG00000261655		4830	3952	rs7386474-?	rs7386474	0	7386474	intergenic_variant	1	NR	3e-06	5.52287874528034		1.2301	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8q24.3	8	142610477	NR	MROH4P - ARC	ENSG00000232722	ENSG00000198576		32596	572	rs7465272-?	rs7465272	0	7465272	regulatory_region_variant	1	NR	9e-06	5.04575749056067		1.2559	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	9q33.2	9	121336257	NR	GSN - STOM	ENSG00000148180	ENSG00000148175		3414	2730	rs767770-?	rs767770	0	767770	regulatory_region_variant	1	NR	6e-06	5.22184874961636		1.7173	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	11q23.3	11	116529665	NR	LINC02151 - AP000770.1	ENSG00000236437	ENSG00000278945		29035	80330	rs7941534-?	rs7941534	0	7941534	intergenic_variant	1	NR	8e-06	5.09691001300806		1.2722	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7q35	7	146262151	CNTNAP2	CNTNAP2			ENSG00000174469	NA	NA	rs802568-?	rs802568	0	802568	intron_variant	0	NR	2e-07	6.69897000433602		2.0307	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	9p13.3	9	33217268	NR	B4GALT1-AS1 - SPINK4	ENSG00000233554	ENSG00000122711		34403	1097	rs830407-?	rs830407	0	830407	intergenic_variant	1	NR	8e-06	5.09691001300806		1.3581	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q14.11	13	40374014	NR	LINC00598			ENSG00000215483	NA	NA	rs913246-?	rs913246	0	913246	intron_variant	0	NR	7e-06	5.15490195998574		1.9374	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	14q12	14	31964652	NR	AL352984.2			ENSG00000275002	NA	NA	rs915071-?	rs915071	0	915071	non_coding_transcript_exon_variant	0	NR	2e-06	5.69897000433602		1.2346	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	6q16.3	6	104145992	NR	NPM1P10 - AL357522.1	ENSG00000214428	ENSG00000287616		119229	341103	rs9377619-?	rs9377619	0	9377619	intergenic_variant	1	NR	2e-06	5.69897000433602		1.3421	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q31.3	13	93688843	NR	GPC6			ENSG00000183098	NA	NA	rs9561428-?	rs9561428	0	9561428	intron_variant	0	NR	9e-06	5.04575749056067		1.8346	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	3p24.2	3	25070680	NR	AC092422.1			ENSG00000237838	NA	NA	rs993804-?	rs993804	0	993804	intron_variant	0	NR	1e-06	6		1.2846	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	3p24.3	3	20067054	NR	KAT2B			ENSG00000114166	NA	NA	rs1124376-?	rs1124376	0	1124376	intron_variant	0	NR	5e-06	5.30102999566398		1.2753	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8q22.1	8	93157121	NR	C8orf87			ENSG00000279847	NA	NA	rs278567-?	rs278567	0	278567	intron_variant	0	NR	8e-06	5.09691001300806		1.247	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	3p24.3	3	20573781	NR	SGO1-AS1			ENSG00000231304	NA	NA	rs1395103-?	rs1395103	0	1395103	intron_variant	0	NR	9e-06	5.04575749056067		1.2382	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q14.1	5	79803641	NR	AC008496.2			ENSG00000250258	NA	NA	rs7735699-?	rs7735699	0	7735699	intron_variant	0	NR	6e-06	5.22184874961636		1.2285	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q12.3	5	65238814	NR	ADAMTS6			ENSG00000049192	NA	NA	rs13183791-?	rs13183791	0	13183791	intron_variant	0	NR	6e-06	5.22184874961636		1.5749	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8p21.2	8	27219081	NR	AC090150.1 - STMN4	ENSG00000253888	ENSG00000015592		8298	16242	rs1446682-?	rs1446682	0	1446682	intergenic_variant	1	NR	6e-06	5.22184874961636		1.2633	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	3q28	3	191478803	NR	AC073365.1			ENSG00000223812	NA	NA	rs16822582-?	rs16822582	0	16822582	intron_variant	0	NR	8e-06	5.09691001300806		1.4994	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	14q12	14	26937686	NR	AL110292.1			ENSG00000258081	NA	NA	rs17111920-?	rs17111920	0	17111920	intron_variant	0	NR	3e-06	5.52287874528034		2.4079	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	16p13.3	16	7703702	NR	RBFOX1			ENSG00000078328	NA	NA	rs12444931-?	rs12444931	0	12444931	intron_variant	0	NR	5e-06	5.30102999566398		1.2244	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	3p14.3	3	54598520	NR	CACNA2D3			ENSG00000157445	NA	NA	rs13064588-?	rs13064588	0	13064588	intron_variant	0	NR	4e-06	5.39794000867204		1.2367	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	22q13.2	22	42274959	NR	OGFRP1, TCF20, TCF20, TCF20, TCF20, TCF20			ENSG00000182057, ENSG00000283681, ENSG00000100207, ENSG00000276461, ENSG00000281897, ENSG00000282892	NA	NA	rs134882-?	rs134882	0	134882	non_coding_transcript_exon_variant	0	NR	7e-06	5.15490195998574		1.2196	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xq21.1	X	83280161	NR	ATG4AP1 - Z82170.1	ENSG00000232735	ENSG00000279437		280925	225862	rs1410530-?	rs1410530	0	1410530	intergenic_variant	1	NR	4e-06	5.39794000867204		1.3746	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xp21.1	X	32207138	NR	DMD			ENSG00000198947	NA	NA	rs1456737-?	rs1456737	0	1456737	intron_variant	0	NR	5e-06	5.30102999566398		1.2492	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	2p24.1	2	22353228	NR	AC096570.1			ENSG00000228999	NA	NA	rs1605834-?	rs1605834	0	1605834	intron_variant	0	NR	8e-06	5.09691001300806		1.3206	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	18q22.1	18	68646835	NR	AC067819.1 - TMX3	ENSG00000264697	ENSG00000166479		118712	26853	rs1704734-?	rs1704734	0	1704734	intergenic_variant	1	NR	6e-06	5.22184874961636		1.3235	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	6q21	6	108002555	NR	MTHFD2P3 - RPL3P7	ENSG00000231112	ENSG00000225093		16524	1802	rs17069122-?	rs17069122	0	17069122	intergenic_variant	1	NR	1e-06	6		2.3265	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5p15.2	5	10811362	NR	AC012629.1 - CTNND2	ENSG00000250576	ENSG00000169862		34300	160474	rs17176973-?	rs17176973	0	17176973	intergenic_variant	1	NR	5e-06	5.30102999566398		1.776	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q22.1	5	111771418	NR	NREP			ENSG00000134986	NA	NA	rs173896-?	rs173896	0	173896	intron_variant	0	NR	7e-06	5.15490195998574		1.4282	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	9q21.33	9	87416754	NR	AL136367.1 - AL353752.1	ENSG00000212421	ENSG00000228373		156169	6880	rs1806864-?	rs1806864	0	1806864	regulatory_region_variant	1	NR	1e-06	6		1.4392	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8q12.1	8	57928365	FAM110B	AC012103.1, LINC01602			ENSG00000253376, ENSG00000205293	NA	NA	rs1992045-?	rs1992045	0	1992045	intron_variant	0	NR	2e-07	6.69897000433602		1.563	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xq21.1	X	83456934	NR	ATG4AP1 - Z82170.1	ENSG00000232735	ENSG00000279437		457698	49089	rs213443-?	rs213443	0	213443	intergenic_variant	1	NR	6e-06	5.22184874961636		1.248	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	20q13.2	20	53993957	NR	BCAS1			ENSG00000064787	NA	NA	rs2276498-?	rs2276498	0	2276498	intron_variant	0	NR	7e-06	5.15490195998574		1.3111	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	11q22.1	11	98254676	CNTN5	AP001317.1 - AP003038.1	ENSG00000255380	ENSG00000254939		123478	310398	rs2509843-?	rs2509843	0	2509843	intergenic_variant	1	NR	2e-07	6.69897000433602		1.2684	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q21.3	5	107388887	NR	EFNA5			ENSG00000184349	NA	NA	rs252817-?	rs252817	0	252817	intron_variant	0	NR	2e-06	5.69897000433602		1.2431	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8p23.3	8	2092276	NR	MYOM2, MYOM2			ENSG00000036448, ENSG00000274137	NA	NA	rs2235121-?	rs2235121	0	2235121	intron_variant	0	NR	8e-06	5.09691001300806		1.221	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	9p24.1	9	6784726	NR	KDM4C			ENSG00000107077	NA	NA	rs10815468-?	rs10815468	0	10815468	intron_variant	0	NR	7e-06	5.15490195998574		1.2194	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	15q14	15	38711562	NR	LINC02694			ENSG00000175779	NA	NA	rs2643217-?	rs2643217	0	2643217	intron_variant	0	NR	6e-06	5.22184874961636		1.2713	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	1p13.2	1	114172962	NR	SYT6 - AL121999.1	ENSG00000134207	ENSG00000232895		19043	33465	rs2774292-?	rs2774292	0	2774292	intergenic_variant	1	NR	3e-06	5.52287874528034		2.0874	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	15q22.2	15	59426970	NR	FAM81A			ENSG00000157470	NA	NA	rs28890483-?	rs28890483	0	28890483	intron_variant	0	NR	9e-06	5.04575749056067		1.3904	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	17q21.2	17	41094387	NR	AC100808.1 - KRTAP4-8	ENSG00000287602	ENSG00000204880		1141	2594	rs4006360-?	rs4006360	0	4006360	intergenic_variant	1	NR	4e-06	5.39794000867204		1.2328	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	16q23.1	16	77882294	NR	VAT1L			ENSG00000171724	NA	NA	rs435746-?	rs435746	0	435746	non_coding_transcript_exon_variant	0	NR	3e-06	5.52287874528034		1.283	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q12.13	13	25463822	NR	ATP8A2			ENSG00000132932	NA	NA	rs4770837-?	rs4770837	0	4770837	intron_variant	0	NR	5e-06	5.30102999566398		1.246	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7p11.2	7	57639445	NR	AC064862.6			ENSG00000243981	NA	NA	rs4870684-?	rs4870684	0	4870684	intron_variant	0	NR	5e-06	5.30102999566398		1.2718	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	1q31.3	1	196073532	NR	LINC01724 - KCNT2	ENSG00000227421	ENSG00000162687		8297	152247	rs7512769-?	rs7512769	0	7512769	intergenic_variant	1	NR	2e-06	5.69897000433602		1.2898	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7p22.3	7	1846899	NR	AC104129.1, AC069288.1, MAD1L1			ENSG00000176349, ENSG00000286192, ENSG00000002822	NA	NA	rs6952808-?	rs6952808	0	6952808	non_coding_transcript_exon_variant	0	NR	2e-06	5.69897000433602		1.2541	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7p22.3	7	2001797	NR	AC069288.1, MAD1L1			ENSG00000286192, ENSG00000002822	NA	NA	rs1107592-?	rs1107592	0	1107592	intron_variant	0	NR	2e-06	5.69897000433602		1.2384	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	10q11.21	10	44627931	NR	AL356157.1 - TMEM72-AS1	ENSG00000234580	ENSG00000224812		25827	165188	rs11239177-?	rs11239177	0	11239177	TF_binding_site_variant	1	NR	3e-06	5.52287874528034		1.2306	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	17q12	17	37666305	NR	AC243571.2			ENSG00000277501	NA	NA	rs6607284-?	rs6607284	0	6607284	intron_variant	0	NR	7e-06	5.15490195998574		1.2262	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7p22.3	7	2258592	NR	SNX8			ENSG00000106266	NA	NA	rs2398668-?	rs2398668	0	2398668	intron_variant	0	NR	7e-06	5.15490195998574		1.2261	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	20p11.21	20	24736449	NR	AL049594.1 - AL035661.1	ENSG00000231015	ENSG00000274173		55458	195391	rs2424635-?	rs2424635	0	2424635	intergenic_variant	1	NR	7e-06	5.15490195998574		1.2261	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7p21.3	7	7359773	NR	COL28A1			ENSG00000215018	NA	NA	rs10486158-?	rs10486158	0	10486158	intron_variant	0	NR	6e-06	5.22184874961636		1.2739	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	10p12.33	10	18099505	NR	SLC39A12 - CACNB2	ENSG00000148482	ENSG00000165995		56213	41172	rs10508558-?	rs10508558	0	10508558	intergenic_variant	1	NR	9e-06	5.04575749056067		1.5425	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	14q23.1	14	57734007	NR	SLC35F4			ENSG00000151812	NA	NA	rs1092015-?	rs1092015	0	1092015	intron_variant	0	NR	8e-06	5.09691001300806		2.0443	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	2p24.3	2	12428870	NR	MIR3681HG			ENSG00000224184	NA	NA	rs10929808-?	rs10929808	0	10929808	intron_variant	0	NR	4e-06	5.39794000867204		1.3678	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7q36.3	7	156255955	LOC393076	Y_RNA - AC093813.1	ENSG00000265852	ENSG00000270584		69732	7592	rs10949808-?	rs10949808	0	10949808	intergenic_variant	1	NR	1e-07	7		1.2699	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8p21.3	8	20208538	NR	ATP6V1B2			ENSG00000147416	NA	NA	rs1106634-?	rs1106634	0	1106634	intron_variant	0	NR	4e-06	5.39794000867204		1.344	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	15q23	15	69357714	NR	PAQR5			ENSG00000137819	NA	NA	rs11072089-?	rs11072089	0	11072089	intron_variant	0	NR	3e-06	5.52287874528034		1.8896	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	4q22.3	4	94224984	NR	SMARCAD1			ENSG00000163104	NA	NA	rs11097407-?	rs11097407	0	11097407	intron_variant	0	NR	4e-06	5.39794000867204		1.2498	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xq28	X	153741041	NR	ABCD1, U52111.1			ENSG00000101986, ENSG00000232725	NA	NA	rs11156606-?	rs11156606	0	11156606	intron_variant	0	NR	3e-06	5.52287874528034		1.4169	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	12q13.11	12	48009982	NR	AC004801.5			ENSG00000258203	NA	NA	rs11168351-?	rs11168351	0	11168351	intron_variant	0	NR	9e-06	5.04575749056067		1.2231	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	10p15.1	10	6365775	NR	LINC02649 - PRKCQ	ENSG00000215244	ENSG00000065675		11948	61368	rs11258317-?	rs11258317	0	11258317	TF_binding_site_variant	1	NR	6e-06	5.22184874961636		1.2306	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q33.3	5	157515277	NR	ADAM19			ENSG00000135074	NA	NA	rs11740562-?	rs11740562	0	11740562	intron_variant	0	NR	1e-06	6		1.5638	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	9q33.1	9	118597008	ASTN2	TPT1P9 - AL355592.1	ENSG00000234782	ENSG00000225050		513626	90744	rs11789399-?	rs11789399	0	11789399	intergenic_variant	1	NR	6e-09	8.22184874961636		1.2935	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5p13.1	5	40626651	NR	TTC33			ENSG00000113638	NA	NA	rs11955175-?	rs11955175	0	11955175	intron_variant	0	NR	6e-06	5.22184874961636		1.467	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	9p22.3	9	15283099	NR	TTC39B			ENSG00000155158	NA	NA	rs12003180-?	rs12003180	0	12003180	intron_variant	0	NR	5e-06	5.30102999566398		1.6032	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	6q15	6	89022382	GABRR1	AL079342.1 - AL079342.2	ENSG00000220130	ENSG00000220960		20568	37246	rs12201676-?	rs12201676	0	12201676	regulatory_region_variant	1	NR	4e-08	7.39794000867204		1.3139	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	11p15.1	11	18244252	NR	SAA2, SAA2-SAA4			ENSG00000134339, ENSG00000255071	NA	NA	rs12282742-?	rs12282742	0	12282742	intron_variant	0	NR	1e-06	6		1.6703	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	12q15	12	68138297	NR	IFNG-AS1			ENSG00000255733	NA	NA	rs12321565-?	rs12321565	0	12321565	intron_variant	0	NR	5e-06	5.30102999566398		1.3481	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	19p13.2	19	11220266	NR	DOCK6			ENSG00000130158	NA	NA	rs17699030-?	rs17699030	0	17699030	intron_variant	0	NR	8e-06	5.09691001300806		1.7062	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	19p13.3	19	3251221	NR	CELF5			ENSG00000161082	NA	NA	rs17764205-?	rs17764205	0	17764205	intron_variant	0	NR	5e-06	5.30102999566398		1.3597	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	11p15.4	11	10718819	NR	MRVI1 - Y_RNA	ENSG00000072952	ENSG00000265852		24831	7084	rs2018368-?	rs2018368	0	2018368	intergenic_variant	1	NR	1e-06	6		1.2392	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7q21.11	7	82156904	NR	CACNA2D1			ENSG00000153956	NA	NA	rs2367911-?	rs2367911	0	2367911	intron_variant	0	NR	5e-06	5.30102999566398		1.771	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5p15.2	5	11298111	NR	CTNND2			ENSG00000169862	NA	NA	rs2530215-?	rs2530215	0	2530215	intron_variant	0	NR	7e-06	5.15490195998574		1.2196	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	6q16.3	6	100308811	NR	AL080285.1 - SIM1	ENSG00000216378	ENSG00000112246		130619	76204	rs2841307-?	rs2841307	0	2841307	intergenic_variant	1	NR	1e-06	6		1.3621	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	1p13.2	1	115333024	NR	NGF-AS1, NGF			ENSG00000228035, ENSG00000134259	NA	NA	rs4332358-?	rs4332358	0	4332358	intron_variant	0	NR	5e-06	5.30102999566398		1.2615	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	22q12.1	22	26615456	NR	CRYBB1			ENSG00000100122	NA	NA	rs4822752-?	rs4822752	0	4822752	intron_variant	0	NR	9e-06	5.04575749056067		1.216	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	1p35.2	1	29959372	PTPRU	AL645944.1 - LINC01648	ENSG00000270927	ENSG00000233399		54015	54580	rs4949526-?	rs4949526	0	4949526	intergenic_variant	1	NR	4e-07	6.39794000867204		1.2805	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q22.2	5	113244593	NR	MCC			ENSG00000171444	NA	NA	rs17323670-?	rs17323670	0	17323670	intron_variant	0	NR	7e-06	5.15490195998574		1.7476	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	11q25	11	131466180	NR	NTM			ENSG00000182667	NA	NA	rs992564-?	rs992564	0	992564	intron_variant	0	NR	4e-06	5.39794000867204		1.6221	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	8q24.12	8	120623156	NR	SNTB1			ENSG00000172164	NA	NA	rs6986718-?	rs6986718	0	6986718	intron_variant	0	NR	9e-06	5.04575749056067		1.5223	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	7p21.3	7	12897630	NR	AC011287.1			ENSG00000229618	NA	NA	rs17166499-?	rs17166499	0	17166499	intron_variant	0	NR	5e-06	5.30102999566398		1.5129	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	Xq27.3	X	145059799	CYCSP44	RN7SKP189 - CYCSP44	ENSG00000201912	ENSG00000233548		2362	116783	rs6627057-?	rs6627057	0	6627057	intergenic_variant	1	NR	1e-06	6		1.4569	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	19p13.3	19	6080471	NR	RFX2			ENSG00000087903	NA	NA	rs11880706-?	rs11880706	0	11880706	intron_variant	0	NR	2e-06	5.69897000433602		1.4393	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	15q22.2	15	62020641	NR	VPS13C			ENSG00000129003	NA	NA	rs4143844-?	rs4143844	0	4143844	intron_variant	0	NR	4e-06	5.39794000867204		1.4298	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	22q13.2	22	40600363	NR	MRTFA			ENSG00000196588	NA	NA	rs17002034-?	rs17002034	0	17002034	intron_variant	0	NR	4e-06	5.39794000867204		1.3976	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	2q21.2	2	133247997	NAP5	NCKAP5			ENSG00000176771	NA	NA	rs10496702-?	rs10496702	0	10496702	intron_variant	0	NR	7e-07	6.15490195998574		1.3968	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	3q26.2	3	170445686	TMEM212	CLDN11, AC026316.4			ENSG00000013297, ENSG00000285218	NA	NA	rs6444931-?	rs6444931	0	6444931	intron_variant	0	NR	6e-07	6.22184874961636		1.3421	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	21p11.2	21	10510446	NR	AF254983.1, BAGE2			ENSG00000273840, ENSG00000187172	NA	NA	rs240444-?	rs240444	0	240444	intron_variant	0	NR	2e-06	5.69897000433602		1.3094	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5p15.32	5	4720472	NR	AC106799.2			ENSG00000248973	NA	NA	rs7727102-?	rs7727102	0	7727102	intron_variant	0	NR	1e-06	6		1.3053	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q32.3	13	101055958	NALCN	NALCN, NALCN-AS1			ENSG00000102452, ENSG00000233009	NA	NA	rs2044117-?	rs2044117	0	2044117	intron_variant	0	NR	5e-07	6.30102999566398		1.3006	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	1p31.1	1	79668438	FAM69A	ADH5P2 - AC099671.1	ENSG00000232676	ENSG00000285409		146235	299295	rs7533906-?	rs7533906	0	7533906	intergenic_variant	1	NR	4e-06	5.39794000867204		1.2982	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	19p13.11	19	18357076	NR	PGPEP1			ENSG00000130517	NA	NA	rs7248363-?	rs7248363	0	7248363	intron_variant	0	NR	1e-06	6		1.296	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	5q11.2	5	51922017	NR	RNA5SP182 - KATNBL1P4	ENSG00000251873	ENSG00000249270		35248	8791	rs10042348-?	rs10042348	0	10042348	intergenic_variant	1	NR	5e-06	5.30102999566398		1.2948	[NR]	Affymetrix [722112]	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	15q25.3	15	86648746	AGBL1	AGBL1			ENSG00000273540	NA	NA	rs2469184-A	rs2469184	0	2469184	intron_variant	0	NR	4e-08	7.39794000867204		0.162	[0.081-0.243] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	1q24.2	1	169582444	SELP, F5	F5			ENSG00000198734	NA	NA	rs6028-C	rs6028	0	6028	synonymous_variant	0	NR	3e-09	8.52287874528034		0.226	[0.14-0.31] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	4q35.2	4	186274397	F11	F11			ENSG00000088926	NA	NA	rs1593-A	rs1593	0	1593	3_prime_UTR_variant	0	NR	2e-18	17.698970004336		0.536	[0.41-0.66] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	4q35.2	4	186286227	F11	F11, F11-AS1			ENSG00000088926, ENSG00000251165	NA	NA	rs2289252-C	rs2289252	0	2289252	non_coding_transcript_exon_variant	0	NR	6e-43	42.2218487496164		0.483	[0.40-0.57] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	3q27.3	3	186672838	AHSG, FETUB, HRG	HRG, AC068631.1			ENSG00000113905, ENSG00000197099	NA	NA	rs9898-C	rs9898	0	9898	missense_variant	0	NR	1e-111	111		1	[0.92-1.08] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	3q27.3	3	186742138	RFC4, ADIPOQ, KNG1	AC068631.1, KNG1			ENSG00000197099, ENSG00000113889	NA	NA	rs710446-C	rs710446	0	710446	missense_variant	0	NR	2e-203	202.698970004336		1.18	[1.10-1.26] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	5q35.3	5	177414338	RGS14, PRR7, DBN1, GRK6, UIMC1, SLC34A1, F12, FGFR4, NSD1, PRELID1, MXD3, LMAN2	GRK6			ENSG00000198055	NA	NA	rs2545801-C	rs2545801	0	2545801	intron_variant	0	NR	6e-88	87.2218487496164		1.68	[1.48-1.88] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	6p21.32	6	32371299	C6orf10	TSBP1-AS1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1			ENSG00000225914, ENSG00000234280, ENSG00000232106, ENSG00000206245, ENSG00000204296, ENSG00000206310, ENSG00000226892, ENSG00000237881, ENSG00000236672	NA	NA	rs2050190-A	rs2050190	0	2050190	intron_variant	0	NR	7e-07	6.15490195998574		0.2528	[0.17-0.34] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Activated partial thromboplastin time	9,240 European ancestry individuals	2611 European ancestry individuals	9q34.2	9	133261662	LOC653163, SURF2, SURF4, ADAMTS13, C9orf7, ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs687621-A	rs687621	0	687621	intron_variant	0	NR	9e-100	99.0457574905607		0.817	[0.73-0.90] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Prothrombin time	2,583 European ancestry individuals	986 European ancestry individuals	13q34	13	113105720	F7	MCF2L - F7	ENSG00000126217	ENSG00000057593		5978	68	rs561241-C	rs561241	0	561241	TF_binding_site_variant	1	NR	4e-56	55.397940008672		0.035	[0.029-0.041] unit increase	Illumina [~ 2500000] (imputed)	N
2012-08-15	22703881	Tang W	2012-06-14	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22703881	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	Prothrombin time	2,583 European ancestry individuals	986 European ancestry individuals	20q11.22	20	35135060	MYH7B, EDEM2, TRPC4AP, PROCR	EDEM2			ENSG00000088298	NA	NA	rs2295888-A	rs2295888	0	2295888	intron_variant	0	NR	5e-13	12.301029995664		0.02	[0.012-0.028] unit decrease	Illumina [~ 2500000] (imputed)	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	1p22.1	1	92936280	NR	DIPK1A			ENSG00000154511	NA	NA	rs12745968-?	rs12745968	0	12745968	intron_variant	0	NR	8e-07	6.09691001300806		1.2527	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	13q34	13	110378231	NR	COL4A2			ENSG00000134871	NA	NA	rs7319311-?	rs7319311	0	7319311	intron_variant	0	NR	4e-06	5.39794000867204		1.2452	[NR]	Affymetrix [722112]	N
2012-11-02	20889312	Wang KS	2010-10-01	Schizophr Res	www.ncbi.nlm.nih.gov/pubmed/20889312	A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.	Bipolar disorder and schizophrenia	651 European ancestry bipolar cases, 1,171 European ancestry schizophrenia cases, 2,412 European ancestry controls	NA	20q11.23	20	38329435	NR	BPI			ENSG00000101425	NA	NA	rs6024905-?	rs6024905	0	6024905	intron_variant	0	NR	1e-06	6		1.2399	[NR]	Affymetrix [722112]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	19q13.11	19	33677367	CHST8	CHST8			ENSG00000124302	NA	NA	rs4805924-?	rs4805924	0	4805924	intron_variant	0	0.02	6e-07	6.22184874961636	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	6p23	6	14598589	intergenic	AL109914.1			ENSG00000229646	NA	NA	rs7770731-?	rs7770731	0	7770731	intron_variant	0	0.29	1e-06	6	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	14q22.2	14	54390568	CDKN3	ATP5F1CP1 - CDKN3	ENSG00000224004	ENSG00000100526		398573	6281	rs4293296-?	rs4293296	0	4293296	intergenic_variant	1	0.29	3e-06	5.52287874528034	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	1p13.3	1	106889954	intergenic	LINC01661 - PRMT6	ENSG00000237460	ENSG00000198890		24638	166720	rs12726652-?	rs12726652	0	12726652	intergenic_variant	1	0.26	5e-07	6.30102999566398	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	12q23.1	12	99872335	ANKS1B	ANKS1B			ENSG00000185046	NA	NA	rs11110077-?	rs11110077	0	11110077	intron_variant	0	0.11	4e-07	6.39794000867204	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	1q42.3	1	236149827	GPR137B	GPR137B			ENSG00000077585	NA	NA	rs7520258-?	rs7520258	0	7520258	intron_variant	0	0.07	5e-07	6.30102999566398	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	11q23.2	11	113439147	DRD2	DRD2			ENSG00000149295	NA	NA	rs11214606-?	rs11214606	0	11214606	intron_variant	0	0.03	5e-07	6.30102999566398	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	4q13.1	4	61571600	LPHN3	ADGRL3			ENSG00000150471	NA	NA	rs6856328-?	rs6856328	0	6856328	intron_variant	0	0.07	8e-07	6.09691001300806	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	3q28	3	190279607	CLDN1	NMNAT1P3 - CLDN1	ENSG00000238077	ENSG00000163347		111956	26100	rs16865258-?	rs16865258	0	16865258	intergenic_variant	1	0.02	2e-06	5.69897000433602	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	2q14.1	2	112771663	IL1A	CKAP2L - IL1A	ENSG00000169607	ENSG00000115008		6999	2252	rs11677416-?	rs11677416	0	11677416	intergenic_variant	1	0.25	7e-07	6.15490195998574	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (working memory)	738 European ancestry, African American, and other ancestry cases	NA	2p23.3	2	24298897	ITSN2	ITSN2			ENSG00000198399	NA	NA	rs6707600-?	rs6707600	0	6707600	intron_variant	0	0.02	3e-06	5.52287874528034	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment	738 European ancestry, African American, and other ancestry cases	NA	11p13	11	34633816	EHF	EHF			ENSG00000135373	NA	NA	rs286913-?	rs286913	0	286913	intron_variant	0	0.05	7e-08	7.15490195998574	(Ziprasidone, vigilance)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment	738 European ancestry, African American, and other ancestry cases	NA	1q32.1	1	205927107	SLC26A9	SLC26A9			ENSG00000174502	NA	NA	rs11240594-?	rs11240594	0	11240594	intron_variant	0	0.19	1e-07	7	(Olanzapine, processing speed)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	21q22.11	21	31912988	HUNK	HUNK			ENSG00000142149	NA	NA	rs2833556-?	rs2833556	0	2833556	intron_variant	0	0.31	5e-07	6.30102999566398	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	3p22.1	3	42406979	LYZL4	LYZL4			ENSG00000157093	NA	NA	rs2286720-?	rs2286720	0	2286720	synonymous_variant	0	0.07	1e-06	6	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	1p36.33	1	2138242	PRKCZ	PRKCZ			ENSG00000067606	NA	NA	rs3753242-?	rs3753242	0	3753242	intron_variant	0	0.06	1e-06	6	(risperidone)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	16q22.1	16	68566448	ZFP90	ZFP90			ENSG00000184939	NA	NA	rs17689437-?	rs17689437	0	17689437	3_prime_UTR_variant	0	0.13	1e-06	6	(risperidone)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	12q13.13	12	51870172	ANKRD33	FIGNL2-DT - ANKRD33	ENSG00000259887	ENSG00000167612		17443	17837	rs17126180-?	rs17126180	0	17126180	intergenic_variant	1	0.06	9e-07	6.04575749056067	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	14q24.2	14	70783085	MAP3K9	MAP3K9			ENSG00000006432	NA	NA	rs17108533-?	rs17108533	0	17108533	intron_variant	0	0.10	1e-06	6	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	8q22.3	8	101215695	ZNF706	AP001330.4 - AP001330.2	ENSG00000271882	ENSG00000253942		7137	8246	rs1264202-?	rs1264202	0	1264202	intergenic_variant	1	0.31	2e-06	5.69897000433602	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	11p12	11	40816163	intergenic	LRRC4C			ENSG00000148948	NA	NA	rs4611189-?	rs4611189	0	4611189	intron_variant	0	0.03	6e-07	6.22184874961636	(quetiapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	16q23.1	16	78536060	WWOX	WWOX			ENSG00000186153	NA	NA	rs17706989-?	rs17706989	0	17706989	intron_variant	0	0.03	1e-06	6	(olanzapine)	NA		Affymetrix [492900]	N
2011-01-08	21107309	McClay JL	2010-11-24	Neuropsychopharmacology	www.ncbi.nlm.nih.gov/pubmed/21107309	Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.	Response to antipsychotic treatment in schizophrenia (reasoning)	738 European ancestry, African American, and other ancestry cases	NA	2q36.3	2	229105082	PID1	PID1			ENSG00000153823	NA	NA	rs6436839-?	rs6436839	0	6436839	intron_variant	0	0.29	3e-06	5.52287874528034	(quetiapine)	NA		Affymetrix [492900]	N
2015-04-14	21699788	Okada Y	2011-06-20	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/21699788	HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.	Ulcerative colitis or Crohn's disease	372 Japanese ancestry Crohn's disease cases, 372 Japanese ancestry ulcerative colitis cases	607 Japanese ancestry Crohn's disease cases, 376 Japanese ancestry ulcerative colitis cases	6p21.32	6	32619077	MHC, HLA-DRB1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		29229	9102	rs9271366-C	rs9271366	0	9271366	intergenic_variant	1	0.21	2e-70	69.698970004336	(UC vs. CD)	4.44	[3.74-5.27]	Illumina [461368]	N
2015-04-14	21699788	Okada Y	2011-06-20	Gastroenterology	www.ncbi.nlm.nih.gov/pubmed/21699788	HLA-Cw*1202-B*5201-DRB1*1502 haplotype increases risk for ulcerative colitis but reduces risk for Crohn's disease.	Ulcerative colitis or Crohn's disease	372 Japanese ancestry Crohn's disease cases, 372 Japanese ancestry ulcerative colitis cases	607 Japanese ancestry Crohn's disease cases, 376 Japanese ancestry ulcerative colitis cases	9q32	9	114830358	TNFSF15	TNFSF15 - AL133412.1	ENSG00000181634	ENSG00000229817		24319	15236	rs2006996-T	rs2006996	0	2006996	regulatory_region_variant	1	0.47	4e-13	12.397940008672	(UC vs. CD)	1.67	[1.47-1.92]	Illumina [461368]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	1p36.22	1	9351410	SPSB1	SPSB1			ENSG00000171621	NA	NA	rs11121382-C	rs11121382	0	11121382	intron_variant	0	NR	4e-06	5.39794000867204		0.099	[0.056-0.142] unit decrease	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	5q31.1	5	135227467	H2AFY, PITX1	C5orf66			ENSG00000224186	NA	NA	rs634308-G	rs634308	0	634308	intron_variant	0	NR	4e-06	5.39794000867204		0.1	[0.057-0.143] unit decrease	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	9q33.1	9	117162816	ASTN2	ASTN2			ENSG00000148219	NA	NA	rs6478282-A	rs6478282	0	6478282	intron_variant	0	NR	6e-06	5.22184874961636		0.101	[0.058-0.144] unit increase	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	13q14.3	13	52943749	OLFM4, PCDH8	PCDH8 - OLFM4	ENSG00000136099	ENSG00000102837		95108	85064	rs732949-C	rs732949	0	732949	regulatory_region_variant	1	NR	8e-06	5.09691001300806		0.166	[0.093-0.239] unit increase	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	18q21.2	18	51164249	SMAD4, MEX3C	SRSF10P1 - MEX3C	ENSG00000267717	ENSG00000176624		4866	10301	rs7230711-C	rs7230711	0	7230711	regulatory_region_variant	1	NR	1e-06	6		0.162	[0.097-0.227] unit decrease	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	4q24	4	105347437	TET2, PPA2	RN7SL89P - PPA2	ENSG00000243383	ENSG00000138777		53491	21640	rs2647264-G	rs2647264	0	2647264	intergenic_variant	1	NR	9e-06	5.04575749056067		0.165	[0.092-0.238] unit increase	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	6p21.32	6	32713899	HLA-DRB1, HLA-DQA1	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		6944	4106	rs3104402-A	rs3104402	0	3104402	regulatory_region_variant	1	NR	6e-06	5.22184874961636		0.165	[0.094-0.236] unit decrease	Affymetrix [736996]	N
2012-07-17	22658931	Pajewski NM	2012-05-30	Vaccine	www.ncbi.nlm.nih.gov/pubmed/22658931	A genome-wide association study of host genetic determinants of the antibody response to Anthrax Vaccine Adsorbed.	Immune response to anthrax vaccine	726 European ancestry individuals	NA	9p21.1	9	32755030	TAF1L, TMEM215	AL157884.1 - TMEM215	ENSG00000230867	ENSG00000188133		27508	28510	rs10758161-G	rs10758161	0	10758161	intergenic_variant	1	NR	8e-06	5.09691001300806		0.159	[0.088-0.230] unit decrease	Affymetrix [736996]	N
2011-07-13	21700879	Qi L	2011-06-23	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21700879	Novel locus FER is associated with serum HMW adiponectin levels.	Adiponectin levels	1,591 European ancestry female individuals	626 European ancestry individuals from 235 families	5q14.1	5	79549888	PAPD4	Y_RNA - Y_RNA	ENSG00000265852	ENSG00000265852		14934	12857	rs13358260-C	rs13358260	0	13358260	intergenic_variant	1	0.93	5e-06	5.30102999566398		NA		Affymetrix [2543887] (imputed)	N
2011-07-13	21700879	Qi L	2011-06-23	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21700879	Novel locus FER is associated with serum HMW adiponectin levels.	Adiponectin levels	1,591 European ancestry female individuals	626 European ancestry individuals from 235 families	8q24.3	8	139507274	KCNK9	AC087354.1 - AC090093.1	ENSG00000254258	ENSG00000275078		44258	1427	rs2468677-G	rs2468677	0	2468677	intergenic_variant	1	0.52	8e-07	6.09691001300806		NA		Affymetrix [2543887] (imputed)	N
2011-07-13	21700879	Qi L	2011-06-23	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21700879	Novel locus FER is associated with serum HMW adiponectin levels.	Adiponectin levels	1,591 European ancestry female individuals	626 European ancestry individuals from 235 families	4p12	4	45362897	AC108043.3-1	THAP12P9 - AC108043.1	ENSG00000248320	ENSG00000224560		36869	51440	rs10517133-C	rs10517133	0	10517133	intergenic_variant	1	0.90	5e-06	5.30102999566398		NA		Affymetrix [2543887] (imputed)	N
2011-07-13	21700879	Qi L	2011-06-23	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21700879	Novel locus FER is associated with serum HMW adiponectin levels.	Adiponectin levels	1,591 European ancestry female individuals	626 European ancestry individuals from 235 families	5q21.3	5	108580035	FER	AC008462.1 - AC133134.1	ENSG00000286503	ENSG00000244245		162019	13574	rs10447248-A	rs10447248	0	10447248	intergenic_variant	1	0.34	5e-08	7.30102999566398		NA		Affymetrix [2543887] (imputed)	N
2011-07-13	21700879	Qi L	2011-06-23	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21700879	Novel locus FER is associated with serum HMW adiponectin levels.	Adiponectin levels	1,591 European ancestry female individuals	626 European ancestry individuals from 235 families	3q27.3	3	186762417	ADIPOQ	AC068631.1			ENSG00000197099	NA	NA	rs822354-A	rs822354	0	822354	intron_variant	0	0.68	4e-08	7.39794000867204		NA		Affymetrix [2543887] (imputed)	N
2010-12-01	20953188	Ellinghaus E	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953188	Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.	Psoriasis	472 European ancestry cases, 1,146 European ancestry controls	2,668, European ancestry cases, 762 French Canadian founder population cases, 2,585 cases, 3,485 European ancestry controls, 994 French Canadian founder population controls, 2,412 controls	6p21.33	6	31285148	HLA-C	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs12191877-?	rs12191877	0	12191877	intron_variant	0	NR	4e-32	31.397940008672		2.79	[2.35-3.33]	Illumina [2339118] (imputed)	N
2010-12-01	20953188	Ellinghaus E	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953188	Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.	Psoriasis	472 European ancestry cases, 1,146 European ancestry controls	2,668, European ancestry cases, 762 French Canadian founder population cases, 2,585 cases, 3,485 European ancestry controls, 994 French Canadian founder population controls, 2,412 controls	6q21	6	111592059	TRAF3IP2	TRAF3IP2, TRAF3IP2-AS1			ENSG00000056972, ENSG00000231889	NA	NA	rs33980500-T	rs33980500	0	33980500	missense_variant	0	0.08	1e-16	16		NA		Illumina [2339118] (imputed)	N
2010-12-01	20953188	Ellinghaus E	2010-10-17	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20953188	Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.	Psoriasis	472 European ancestry cases, 1,146 European ancestry controls	2,668, European ancestry cases, 762 French Canadian founder population cases, 2,585 cases, 3,485 European ancestry controls, 994 French Canadian founder population controls, 2,412 controls	5q33.3	5	159332892	IL12B	AC008691.1			ENSG00000249738	NA	NA	rs2546890-A	rs2546890	0	2546890	non_coding_transcript_exon_variant	0	0.56	1e-20	20		1.54	[1.32-1.79]	Illumina [2339118] (imputed)	N
2011-11-30	22028671	Surakka I	2011-10-20	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22028671	A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.	Lipid traits	Up to 32,225 European ancestry individuals	11,509 European ancestry individuals, 11,163 individuals	4p15.1	4	31395996	PCDH7	AC104071.1 - LINC02501	ENSG00000251434	ENSG00000249882		44271	110426	rs6448771-?	rs6448771	0	6448771	intergenic_variant	1	NR	5e-09	8.30102999566398		0.028	[-0.00728-0.06328] unit increase	Affymetrix, Illumina, Perlegen [~ 2500000] (imputed)	N
2013-03-22	23303382	Hong KW	2013-01-10	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23303382	Genome-wide association study of serum albumin:globulin ratio in Korean populations.	Hematology traits	4,637 East Asian ancestry individuals	4,205 East Asian ancestry individuals	1q42.13	1	230253243	GALNT2	GALNT2			ENSG00000143641	NA	NA	rs3761944-C	rs3761944	0	3761944	intron_variant	0	0.224	8e-06	5.09691001300806	(ALB/GLB)	0.016	[0.0082-0.0238] unit increase	Affymetrix [290659]	N
2013-03-22	23303382	Hong KW	2013-01-10	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23303382	Genome-wide association study of serum albumin:globulin ratio in Korean populations.	Hematology traits	4,637 East Asian ancestry individuals	4,205 East Asian ancestry individuals	6p25.3	6	252145	IRF4	AL035696.1 - AL365272.1	ENSG00000205653	ENSG00000287265		45753	33298	rs6927090-A	rs6927090	0	6927090	regulatory_region_variant	1	0.282	4e-06	5.39794000867204	(ALB/GLB)	0.015	[0.0091-0.0209] unit increase	Affymetrix [290659]	N
2013-03-22	23303382	Hong KW	2013-01-10	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23303382	Genome-wide association study of serum albumin:globulin ratio in Korean populations.	Hematology traits	4,637 East Asian ancestry individuals	4,205 East Asian ancestry individuals	9q32	9	113234969	SLC31A1	SLC31A1			ENSG00000136868	NA	NA	rs6477998-C	rs6477998	0	6477998	intron_variant	0	0.467	8e-06	5.09691001300806	(ALB/GLB)	0.013	[0.0071-0.0189] unit increase	Affymetrix [290659]	N
2013-03-22	23303382	Hong KW	2013-01-10	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23303382	Genome-wide association study of serum albumin:globulin ratio in Korean populations.	Hematology traits	4,637 East Asian ancestry individuals	4,205 East Asian ancestry individuals	11q12.2	11	61803876	FADS1	FADS1, FADS2			ENSG00000149485, ENSG00000134824	NA	NA	rs174548-G	rs174548	0	174548	5_prime_UTR_variant	0	0.319	4e-08	7.39794000867204	(ALB/GLB)	0.017	[0.011-0.023] unit increase	Affymetrix [290659]	N
2013-03-22	23303382	Hong KW	2013-01-10	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23303382	Genome-wide association study of serum albumin:globulin ratio in Korean populations.	Hematology traits	4,637 East Asian ancestry individuals	4,205 East Asian ancestry individuals	17p11.2	17	16945436	TNFRSF13B	TNFRSF13B			ENSG00000240505	NA	NA	rs4561508-T	rs4561508	0	4561508	intron_variant	0	0.335	8e-24	23.0969100130081	(ALB/GLB)	0.031	[0.025-0.037] unit increase	Affymetrix [290659]	N
2011-01-06	21088011	Erdmann J	2010-11-18	Eur Heart J	www.ncbi.nlm.nih.gov/pubmed/21088011	Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.	Coronary heart disease	1,157 European ancestry cases, 1,748 European ancestry controls	7,887 European ancestry cases, 8,244 European ancestry controls	10p11.23	10	30027143	KIAA1462	JCAD			ENSG00000165757	NA	NA	rs3739998-C	rs3739998	0	3739998	missense_variant	0	0.44	1e-11	11		1.15	[1.11-1.20]	Affymetrix [254558]	N
2011-12-02	22037551	Shi Y	2011-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22037551	A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.	Gastric cancer	1,006 Han Chinese ancestry cases, 2,273 Han Chinese ancestry controls	3,288 Han Chinese ancestry cases, 3,609 Han Chinese ancestry controls	3q13.31	3	114643917	ZBTB20	ZBTB20			ENSG00000181722	NA	NA	rs9841504-?	rs9841504	0	9841504	intron_variant	0	NR	2e-09	8.69897000433602		1.32	[1.20-1.45]	Affymetrix [555896]	N
2011-12-02	22037551	Shi Y	2011-10-30	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22037551	A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.	Gastric cancer	1,006 Han Chinese ancestry cases, 2,273 Han Chinese ancestry controls	3,288 Han Chinese ancestry cases, 3,609 Han Chinese ancestry controls	5p13.1	5	40791782	PRKAA1, PTGER4	PRKAA1			ENSG00000132356	NA	NA	rs13361707-?	rs13361707	0	13361707	intron_variant	0	NR	8e-29	28.0969100130081		1.41	[1.32-1.49]	Affymetrix [555896]	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	10q22.1	10	68952306	DDX21	DDX50 - DDX21	ENSG00000107625	ENSG00000165732		5459	3864	rs2017305-A	rs2017305	0	2017305	intergenic_variant	1	0.92	9e-06	5.04575749056067		0.22	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	15q22.2	15	60974897	RORA	RORA			ENSG00000069667	NA	NA	rs12912233-T	rs12912233	0	12912233	intron_variant	0	0.46	6e-07	6.22184874961636		0.15	[NR] unit increase	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	13q33.3	13	107127968	FAM155A	AL354741.1 - FAM155A	ENSG00000285643	ENSG00000204442		166576	35542	rs1927745-A	rs1927745	0	1927745	intergenic_variant	1	0.24	5e-06	5.30102999566398		0.16	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	5p14.3	5	19440059	CDH18	HSPD1P15 - CDH18	ENSG00000249557	ENSG00000145526		205572	31237	rs349475-T	rs349475	0	349475	intergenic_variant	1	0.29	2e-06	5.69897000433602		0.18	[NR] unit increase	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	17q12	17	35516493	SLFN12L	AC015911.11, SLFN12L			ENSG00000286065, ENSG00000205045	NA	NA	rs8070473-T	rs8070473	0	8070473	intron_variant	0	0.32	2e-06	5.69897000433602		0.16	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	10p11.22	10	33005847	ITGB1	ITGB1-DT			ENSG00000229656	NA	NA	rs11009175-A	rs11009175	0	11009175	intron_variant	0	0.17	5e-06	5.30102999566398		0.16	[NR] unit increase	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	2p24.1	2	23191780	intergenic	AC018467.1			ENSG00000232451	NA	NA	rs1449984-A	rs1449984	0	1449984	intron_variant	0	0.72	7e-06	5.15490195998574		0.15	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	11p15.4	11	7993230	EIF3F	EIF3F			ENSG00000175390	NA	NA	rs12420464-T	rs12420464	0	12420464	intron_variant	0	0.04	3e-06	5.52287874528034		0.38	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	16q23.3	16	83250733	CDH13	CDH13			ENSG00000140945	NA	NA	rs10514585-A	rs10514585	0	10514585	intron_variant	0	0.31	5e-06	5.30102999566398		0.15	[NR] unit increase	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	7q31.33	7	126999550	GRM8	GRM8			ENSG00000179603	NA	NA	rs17864092-T	rs17864092	0	17864092	intron_variant	0	0.90	6e-06	5.22184874961636		0.17	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2010-09-28	20800221	Terracciano A	2010-08-25	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/20800221	Genome-wide association scan of trait depression.	Depression (quantitative trait)	3,972 Sardinian individuals, 839 European ancestry individuals	NA	12q24.32	12	127329196	intergenic	LINC02375			ENSG00000256362	NA	NA	rs10744304-A	rs10744304	0	10744304	intron_variant	0	0.63	9e-06	5.04575749056067		0.15	[NR] unit decrease	Affymetrix, Illumina [up to 2500000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	3q27.3	3	187999752	intergenic	AC092941.1			ENSG00000225058	NA	NA	rs4686914-T	rs4686914	0	4686914	intron_variant	0	0.38	3e-21	20.5228787452803	(BUN)	0.0242	[0.019-0.029] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.13	12	112379979	C12orf51	HECTD4			ENSG00000173064	NA	NA	rs11066280-A	rs11066280	0	11066280	intron_variant	0	0.17	8e-22	21.0969100130081	(ALT)	0.0045	[0.0035-0.0055] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	22q13.31	22	43930116	PNPLA3	PNPLA3			ENSG00000100344	NA	NA	rs12483959-A	rs12483959	0	12483959	intron_variant	0	0.42	2e-39	38.698970004336	(ALT)	0.001	[0.00080-0.00120] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	6q22.33	6	127172466	RSPO3	RSPO3, AL356534.1			ENSG00000146374, ENSG00000286215	NA	NA	rs6569474-A	rs6569474	0	6569474	intron_variant	0	0.47	1e-08	8	(BUN)	0.009	[0.0059-0.0121] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	3p14.1	3	66759518	intergenic	RPL21P41 - AC098969.2	ENSG00000214560	ENSG00000288039		122106	20558	rs13069049-T	rs13069049	0	13069049	intergenic_variant	1	0.17	3e-18	17.5228787452803	(BUN)	0.0182	[0.014-0.022] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	18q12.3	18	45622439	SLC14A2	AC023421.2, SLC14A2			ENSG00000267193, ENSG00000132874	NA	NA	rs7232775-C	rs7232775	0	7232775	intron_variant	0	0.20	8e-14	13.0969100130081	(BUN)	0.0148	[0.011-0.019] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	22q13.31	22	43930116	PNPLA3	PNPLA3			ENSG00000100344	NA	NA	rs12483959-A	rs12483959	0	12483959	intron_variant	0	0.42	2e-18	17.698970004336	(ALT)	0.0039	[0.0031-0.0047] IU/L decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.13	12	112379979	C12orf51	HECTD4			ENSG00000173064	NA	NA	rs11066280-A	rs11066280	0	11066280	intron_variant	0	0.17	3e-63	62.5228787452803	(ALT)	0.0016	[0.0014-0.0018] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	2p23.3	2	27520287	GCKR	GCKR			ENSG00000084734	NA	NA	rs780092-G	rs780092	0	780092	intron_variant	0	0.33	5e-18	17.301029995664	(ALB)	0.0232	[-0.02972-0.07612] g/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Triglycerides	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	8p21.3	8	19990179	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		22920	88935	rs10503669-T	rs10503669	0	10503669	intergenic_variant	1	0.12	7e-39	38.1549019599857		0.0857	[0.073-0.098] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Triglycerides	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	8q24.13	8	125465736	intergenic	TRIB1 - AC091114.1	ENSG00000173334	ENSG00000253111		27333	1203	rs2001945-C	rs2001945	0	2001945	intergenic_variant	1	0.42	1e-20	20		0.0405	[0.032-0.049] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Triglycerides	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	11q23.3	11	116783719	ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13	ZPR1			ENSG00000109917	NA	NA	rs603446-T	rs603446	0	603446	intron_variant	0	0.23	2e-86	85.698970004336		0.0876	[0.079-0.096] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Triglycerides	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	2p23.3	2	27520287	GCKR	GCKR			ENSG00000084734	NA	NA	rs780092-G	rs780092	0	780092	intron_variant	0	0.33	5e-27	26.301029995664		0.05	[0.041-0.059] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Triglycerides	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	7q11.23	7	73573024	TBL2, MLXIPL	TBL2			ENSG00000106638	NA	NA	rs2286276-T	rs2286276	0	2286276	non_coding_transcript_exon_variant	0	0.10	1e-15	15		0.0652	[0.049-0.081] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	15q26.2	15	96301498	intergenic	NR2F2-AS1			ENSG00000247809	NA	NA	rs7181753-T	rs7181753	0	7181753	intron_variant	0	0.199	3e-06	5.52287874528034		0.128	[NR] unit increase	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	21q22.13	21	37654970	KCNJ6	KCNJ6, AP001407.1			ENSG00000157542, ENSG00000286717	NA	NA	rs2835872-G	rs2835872	0	2835872	intron_variant	0	0.681	5e-10	9.30102999566398		0.145	[NR] unit decrease	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	14q32.2	14	100217855	intergenic	AL133523.1			ENSG00000258982	NA	NA	rs2766692-G	rs2766692	0	2766692	intron_variant	0	0.691	2e-06	5.69897000433602		0.11	[NR] unit decrease	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	22q13.31	22	44787134	PRR5, ARHGAP8	PRR5-ARHGAP8, ARHGAP8			ENSG00000248405, ENSG00000241484	NA	NA	rs16992796-G	rs16992796	0	16992796	intron_variant	0	0.05	3e-06	5.52287874528034		0.236	[NR] unit decrease	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	3p11.2	3	87734826	intergenic	AC108749.1			ENSG00000239572	NA	NA	rs9860340-A	rs9860340	0	9860340	intron_variant	0	0.749	4e-06	5.39794000867204		0.122	[NR] unit decrease	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	6p12.1	6	53442896	intergenic	NANOGP3 - GCLC	ENSG00000271373	ENSG00000001084		24159	54445	rs9395865-T	rs9395865	0	9395865	intergenic_variant	1	0.279	6e-06	5.22184874961636		0.106	[NR] unit increase	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	11q13.1	11	63825149	C11orf84	SPINDOC			ENSG00000168005	NA	NA	rs10897449-T	rs10897449	0	10897449	intron_variant	0	0.453	7e-06	5.15490195998574		0.099	[NR] unit decrease	Illumina [634583]	N
2012-07-03	22554406	Kang SJ	2012-05-03	Genes Brain Behav	www.ncbi.nlm.nih.gov/pubmed/22554406	Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6.	Electroencephalographic traits in alcoholism	1,560 European ancestry individuals from 117 families	NA	6p22.3	6	24862847	FAM65B	RIPOR2			ENSG00000111913	NA	NA	rs4256430-A	rs4256430	0	4256430	intron_variant	0	0.465	8e-06	5.09691001300806		0.099	[NR] unit decrease	Illumina [634583]	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	5q21.1	5	99244260	CHD1	LINC02062 - AC114324.2	ENSG00000248489	ENSG00000249444		249247	245299	rs17736767-G	rs17736767	0	17736767	intergenic_variant	1	0.27	7e-06	5.15490195998574		0.208	[0.12-0.30] unit decrease	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	21q22.11	21	31445194	TIAM1	TIAM1			ENSG00000156299	NA	NA	rs580140-G	rs580140	0	580140	intron_variant	0	0.28	3e-06	5.52287874528034		0.184	[0.11-0.26] unit decrease	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	12q24.33	12	128840393	GLT1D1	AC108704.1 - GLT1D1	ENSG00000274695	ENSG00000151948		12814	13034	rs10744391-A	rs10744391	0	10744391	intergenic_variant	1	0.29	1e-06	6		0.224	[0.13-0.31] unit decrease	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	9q21.11	9	69251016	TJP2	TJP2, AL358113.1			ENSG00000119139, ENSG00000285130	NA	NA	rs2282335-A	rs2282335	0	2282335	intron_variant	0	0.36	4e-06	5.39794000867204		0.171	[0.098-0.244] unit increase	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	6q22.33	6	129895365	C6orf191	TMEM244 - L3MBTL3	ENSG00000203756	ENSG00000198945		33818	118334	rs9375674-A	rs9375674	0	9375674	regulatory_region_variant	1	0.46	6e-06	5.22184874961636		0.158	[0.089-0.227] unit increase	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	13q31.3	13	94218511	GPC6	GPC6			ENSG00000183098	NA	NA	rs1572050-A	rs1572050	0	1572050	intron_variant	0	0.10	6e-06	5.22184874961636		0.313	[0.18-0.45] unit decrease	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	11q22.3	11	110525134	ARHGAP20	FDX1 - ARHGAP20	ENSG00000137714	ENSG00000137727		60250	51908	rs12785341-C	rs12785341	0	12785341	regulatory_region_variant	1	0.09	8e-06	5.09691001300806		0.29	[0.16-0.42] unit increase	Affymetrix [~ 2500000] (imputed)	N
2011-12-03	22044751	Foster MC	2011-11-01	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/22044751	Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study.	Renal sinus fat	2,809 European ancestry individuals	NA	1q23.1	1	157467720	FCRL5	AL353899.1 - FCRL5	ENSG00000286005	ENSG00000143297		29966	45657	rs6686423-A	rs6686423	0	6686423	intergenic_variant	1	0.31	8e-06	5.09691001300806		0.194	[0.11-0.28] unit decrease	Affymetrix [~ 2500000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.11	12	110976657	MYL2	LINC01405 - CUX2	ENSG00000185847	ENSG00000111249		17564	57508	rs12229654-G	rs12229654	0	12229654	intergenic_variant	1	0.14	9e-58	57.0457574905607		0.0119	[0.011-0.013] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.31	12	120986153	HNF1A	HNF1A			ENSG00000135100	NA	NA	rs2393791-G	rs2393791	0	2393791	intron_variant	0	0.48	7e-30	29.1549019599857		0.0076	[0.0062-0.0090] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	4q31.22	4	145900258	ZNF827	ZNF827			ENSG00000151612	NA	NA	rs4835265-T	rs4835265	0	4835265	intron_variant	0	0.42	1e-14	14		0.0043	[0.0031-0.0055] IU/L decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	7q11.23	7	73563568	TBL2	BCL7B - TBL2	ENSG00000106635	ENSG00000106638		5878	3969	rs12539316-C	rs12539316	0	12539316	intergenic_variant	1	0.10	6e-10	9.22184874961636		0.0051	[0.0035-0.0067] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.13	12	112207597	C12orf51	HECTD4			ENSG00000173064	NA	NA	rs2074356-T	rs2074356	0	2074356	intron_variant	0	0.15	3e-126	125.52287874528		0.0161	[0.015-0.017] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.13	12	112927816	intergenic	OAS1, AC004551.1			ENSG00000089127, ENSG00000257452	NA	NA	rs11066453-G	rs11066453	0	11066453	intron_variant	0	0.13	6e-44	43.2218487496164		0.0097	[0.0083-0.0111] IU/L increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Gamma glutamyl transpeptidase	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	22q11.23	22	24594246	GGT1, C22orf36	GGT1, GGT1			ENSG00000286070, ENSG00000100031	NA	NA	rs4820599-G	rs4820599	0	4820599	intron_variant	0	0.24	7e-53	52.1549019599857		0.0088	[0.0076-0.0100] IU/L decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.11	12	110976657	MYL2	LINC01405 - CUX2	ENSG00000185847	ENSG00000111249		17564	57508	rs12229654-G	rs12229654	0	12229654	intergenic_variant	1	0.14	3e-23	22.5228787452803		0.028	[0.023-0.033] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	9q31.1	9	104891145	ABCA1	ABCA1			ENSG00000165029	NA	NA	rs12686004-T	rs12686004	0	12686004	intron_variant	0	0.21	2e-18	17.698970004336		0.0217	[0.017-0.027] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	11q23.3	11	116746524	intergenic	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		88229	1646	rs11216126-C	rs11216126	0	11216126	intergenic_variant	1	0.20	3e-34	33.5228787452803		0.0322	[0.027-0.037] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	16q13	16	56978467	CETP	CETP			ENSG00000087237	NA	NA	rs12708980-C	rs12708980	0	12708980	intron_variant	0	0.10	2e-28	27.698970004336		0.0396	[0.033-0.047] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.13	12	112207597	C12orf51	HECTD4			ENSG00000173064	NA	NA	rs2074356-T	rs2074356	0	2074356	intron_variant	0	0.15	7e-37	36.1549019599857		0.035	[0.030-0.040] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	19q13.32	19	44873027	APOE, PVRL2, TOMM40	NECTIN2			ENSG00000130202	NA	NA	rs519113-C	rs519113	0	519113	intron_variant	0	0.15	8e-11	10.0969100130081		0.0179	[0.012-0.023] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	8p21.3	8	19990179	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		22920	88935	rs10503669-T	rs10503669	0	10503669	intergenic_variant	1	0.12	8e-43	42.0969100130081		0.0426	[0.037-0.049] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	12q24.13	12	112971371	OAS3	AC004551.1, OAS3			ENSG00000257452, ENSG00000111331	NA	NA	rs2072134-A	rs2072134	0	2072134	3_prime_UTR_variant	0	0.11	6e-06	5.22184874961636		0.0204	[0.012-0.029] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	HDL cholesterol	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	15q21.3	15	58401821	intergenic	ALDH1A2			ENSG00000128918	NA	NA	rs16940212-T	rs16940212	0	16940212	intron_variant	0	0.34	1e-24	24		0.0222	[0.018-0.027] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	9q34.2	9	133278431	ABO	ABO - Y_RNA	ENSG00000281879	ENSG00000265852		2407	59297	rs651007-A	rs651007	0	651007	intergenic_variant	1	0.26	6e-09	8.22184874961636	(LDL)	2.2778	[1.51-3.05] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	1p13.3	1	109279544	CELSR2, PSRC1, SORT1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		3793	12	rs599839-G	rs599839	0	599839	intergenic_variant	1	0.06	2e-19	18.698970004336	(LDL)	5.2254	[4.09-6.37] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	19p13.2	19	11116650	LDLR	LDLR			ENSG00000130164	NA	NA	rs2738446-C	rs2738446	0	2738446	intron_variant	0	0.14	2e-12	11.698970004336	(LDL)	2.9507	[2.13-3.77] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	2p21	2	44961214	SIX2, SIX3	AC012354.1			ENSG00000225156	NA	NA	rs895636-A	rs895636	0	895636	non_coding_transcript_exon_variant	0	0.38	1e-12	12	(FPG)	0.0393	[0.029-0.050] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	7p13	7	44189469	GCK	GCK			ENSG00000106633	NA	NA	rs1799884-A	rs1799884	0	1799884	intron_variant	0	0.19	2e-19	18.698970004336	(FPG)	0.0619	[0.049-0.075] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	11q14.3	11	92965261	MTNR1B	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		27595	536	rs10830962-C	rs10830962	0	10830962	intergenic_variant	1	0.45	1e-16	16	(FPG)	0.0445	[0.034-0.055] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	5q13.3	5	75352778	HMGCR	HMGCR			ENSG00000113161	NA	NA	rs12654264-T	rs12654264	0	12654264	intron_variant	0	0.48	1e-20	20	(LDL)	2.7106	[2.14-3.28] mg/dL decrease	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	2q31.1	2	168927903	ABCB11	ABCB11			ENSG00000073734	NA	NA	rs16856247-T	rs16856247	0	16856247	intron_variant	0	0.35	2e-15	14.698970004336	(FPG)	0.0556	[0.042-0.069] mg/dL increase	Affymetrix [~ 2200000] (imputed)	N
2011-10-11	21909109	Kim YJ	2011-09-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21909109	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	Metabolite levels	12,545 Korean ancestry individuals	Up to 30,395 East Asian ancestry individuals	19q13.33	19	49496752	RPS11	RPS11			ENSG00000142534	NA	NA	rs2280401-A	rs2280401	0	2280401	intron_variant	0	0.17	9e-13	12.0457574905607	(ALB)	0.0293	[0.021-0.037] g/dL increase	Affymetrix [~ 2200000] (imputed)	N
2012-03-09	22293688	Huang J	2012-02-01	Eur J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22293688	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.	Type 1 diabetes	16,179 European ancestry individuals	NA	10p15.1	10	6052734	IL2RA	IL2RA			ENSG00000134460	NA	NA	rs61839660-?	rs61839660	0	61839660	intron_variant	0	NR	5e-09	8.30102999566398		1.6	[1.44-1.76]	NR [6233112] (imputed)	N
2012-03-09	22293688	Huang J	2012-02-01	Eur J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22293688	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.	Type 1 diabetes	16,179 European ancestry individuals	NA	12q24.11	12	111270654	CUX2	CUX2			ENSG00000111249	NA	NA	rs1265564-?	rs1265564	0	1265564	non_coding_transcript_exon_variant	0	NR	1e-16	16		1.45	[1.28-1.67]	NR [6233112] (imputed)	N
2012-03-10	22293688	Huang J	2012-02-01	Eur J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22293688	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.	Type 2 diabetes	16,179 European ancestry individuals	NA	9p21.3	9	22137686	CDKN2B	CDKN2B-AS1 - AL157937.1	ENSG00000240498	ENSG00000236921		9583	66304	rs7018475-?	rs7018475	0	7018475	regulatory_region_variant	1	NR	3e-08	7.52287874528034		1.35	[1.18-1.56]	NR [6233112] (imputed)	N
2012-03-10	22293688	Huang J	2012-02-01	Eur J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/22293688	1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.	Crohn's disease	16,179 European ancestry individuals	NA	1p31.3	1	67240275	IL23R	IL23R			ENSG00000162594	NA	NA	rs11209026-?	rs11209026	0	11209026	missense_variant	0	NR	4e-21	20.397940008672		3.18	[2.91-3.44]	NR [6233112] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	19q13.32	19	44919689	APOE, TOMM40, APOC1	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-?	rs4420638	0	4420638	regulatory_region_variant	1	NR	8e-149	148.096910013008		3.45	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	5q12.1	5	61654384	FLJ37543	C5orf64			ENSG00000178722	NA	NA	rs11738335-?	rs11738335	0	11738335	intron_variant	0	NR	5e-06	5.30102999566398		1.2	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	11q22.2	11	102862432	MMP3, MMP12	MMP3 - MMP12	ENSG00000149968	ENSG00000262406		18823	304	rs12808148-?	rs12808148	0	12808148	intergenic_variant	1	NR	1e-06	6		1.23	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	2q12.3	2	107062032	intergenic	AC005040.2 - LINC01789	ENSG00000286218	ENSG00000229457		65498	192659	rs1357692-?	rs1357692	0	1357692	intergenic_variant	1	NR	9e-06	5.04575749056067		1.16	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	2q14.3	2	127132061	BIN1	BIN1 - AC110926.2	ENSG00000136717	ENSG00000286400		24773	9915	rs7561528-?	rs7561528	0	7561528	intergenic_variant	1	NR	6e-11	10.2218487496164		1.25	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	11q14.2	11	85966428	PICALM	PICALM			ENSG00000073921	NA	NA	rs17817600-?	rs17817600	0	17817600	intron_variant	0	NR	2e-08	7.69897000433602		1.33	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	8p23.1	8	9141509	PPP1R3B	AC022784.5, PPP1R3B, PPP1R3B			ENSG00000254340, ENSG00000285343, ENSG00000173281	NA	NA	rs3748140-?	rs3748140	0	3748140	missense_variant	0	NR	3e-07	6.52287874528034		2.43	[NR]	Illumina [2543888] (imputed)	N
2012-08-14	22832961	Kamboh MI	2012-05-15	Transl Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22832961	Genome-wide association study of Alzheimer's disease.	Alzheimer's disease	1,291 European ancestry cases, 938 European ancestry controls	509 European ancestry cases, 753 European ancestry controls, 2,218 cases, 2,583 controls	4p15.1	4	30466544	intergenic	AC106868.1 - AC098595.1	ENSG00000248281	ENSG00000286596		458228	252261	rs6856768-?	rs6856768	0	6856768	intergenic_variant	1	NR	5e-06	5.30102999566398		1.18	[NR]	Illumina [2543888] (imputed)	N
2011-11-02	21983785	Macgregor S	2011-10-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21983785	Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.	Melanoma	2,168 European ancestry cases, 4,387 European ancestry controls	5,193 European ancestry cases, 15,144 European ancestry controls	1q21.3	1	150887995	ARNT, SETDB1, LASS2, ANXA9, MCL1, CTSK	CTXND2			ENSG00000283324	NA	NA	rs7412746-T	rs7412746	0	7412746	intron_variant	0	0.55	9e-11	10.0457574905607		1.15	[NR]	Illumina [5480804] (imputed)	N
2011-11-02	21983785	Macgregor S	2011-10-09	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/21983785	Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.	Melanoma	2,168 European ancestry cases, 4,387 European ancestry controls	5,193 European ancestry cases, 15,144 European ancestry controls	1q42.12	1	226376990	PARP1	PARP1			ENSG00000143799	NA	NA	rs3219090-C	rs3219090	0	3219090	intron_variant	0	0.67	9e-08	7.04575749056067		1.15	[NR]	Illumina [5480804] (imputed)	N
2012-01-27	22086417	Cozen W	2011-11-15	Blood	www.ncbi.nlm.nih.gov/pubmed/22086417	A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32.	Nodular sclerosis Hodgkin lymphoma	393 European ancestry cases, 3,315 European ancestry controls	113 European ancestry cases, 214 European ancestry controls	6p21.32	6;6;6;6;6	32460508;32604474;32142202;32415331;32416944	HLA-DQB1, HLA-DRB1	HLA-DRB9; HLA-DRB1 - HLA-DQA1; FKBPL - PRRT1; TSBP1-AS1 - HLA-DRA; TSBP1-AS1 - HLA-DRA				NA	NA	rs6903608-T; rs2858870-C; rs204999-G; rs9268528-A; rs9268542-A	rs6903608; rs2858870; rs204999; rs9268528; rs9268542	0	NA	intron_variant; intron_variant; intergenic_variant; regulatory_region_variant; intergenic_variant	NA	NR	8e-18	17.0969100130081		2.5	[NR]	Illumina [705591]	N
2012-01-27	22086417	Cozen W	2011-11-15	Blood	www.ncbi.nlm.nih.gov/pubmed/22086417	A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32.	Nodular sclerosis Hodgkin lymphoma	393 European ancestry cases, 3,315 European ancestry controls	113 European ancestry cases, 214 European ancestry controls	6p21.32	6;6;6;6;6	32460508;32604474;32142202;32415331;32416944	HLA-DQB1, HLA-DRB1	HLA-DRB9; HLA-DRB1 - HLA-DQA1; FKBPL - PRRT1; TSBP1-AS1 - HLA-DRA; TSBP1-AS1 - HLA-DRA				NA	NA	rs6903608-C; rs2858870-T; rs204999-A; rs9268528-G; rs9268542-G	rs6903608; rs2858870; rs204999; rs9268528; rs9268542	0	NA	intron_variant; intron_variant; intergenic_variant; regulatory_region_variant; intergenic_variant	NA	NR	2e-07	6.69897000433602		1.7	[NR]	Illumina [705591]	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	1p36.22	1	11796321	MTHFR	MTHFR			ENSG00000177000	NA	NA	rs1801133-A	rs1801133	0	1801133	missense_variant	0	0.34	4e-104	103.397940008672		0.1583	[0.14-0.17] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	1q43	1	236885376	MTR	MTR			ENSG00000116984	NA	NA	rs2275565-T	rs2275565	0	2275565	intron_variant	0	0.21	2e-10	9.69897000433602		0.0542	[0.037-0.072] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	2q34	2	210675783	CPS1	CPS1			ENSG00000021826	NA	NA	rs7422339-A	rs7422339	1	1047891	missense_variant	0	0.33	5e-27	26.301029995664		0.0864	[0.071-0.102] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	6p12.3	6	49414480	MUT	EEF1A1P42 - MMUT	ENSG00000277043	ENSG00000146085		54060	15880	rs9369898-A	rs9369898	0	9369898	intergenic_variant	1	0.62	2e-10	9.69897000433602		0.0449	[0.031-0.059] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	11q14.3	11	89415204	NOX4	NOX4			ENSG00000086991	NA	NA	rs7130284-T	rs7130284	0	7130284	intron_variant	0	0.07	2e-20	19.698970004336		0.1242	[0.099-0.15] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	16q24.3	16	89641688	DPEP1	DPEP1 - CHMP1A	ENSG00000015413	ENSG00000131165		3232	2747	rs154657-A	rs154657	0	154657	regulatory_region_variant	1	0.47	2e-43	42.698970004336		0.0963	[0.083-0.11] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	21q22.3	21	43066854	CBS	CBS			ENSG00000160200	NA	NA	rs234709-T	rs234709	0	234709	intron_variant	0	0.45	4e-24	23.397940008672		0.0718	[0.058-0.086] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	1p34.1	1	45513003	MMACHC	MMACHC, PRDX1			ENSG00000132763, ENSG00000117450	NA	NA	rs4660306-T	rs4660306	0	4660306	3_prime_UTR_variant	0	0.33	2e-09	8.69897000433602		0.0435	[0.03-0.057] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	6p22.2	6	25869143	SLC17A3	SLC17A3			ENSG00000124564	NA	NA	rs548987-C	rs548987	0	548987	intron_variant	0	0.13	1e-08	8		0.0597	[0.04-0.079] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	7q21.13	7	90348446	GTPB10	GTPBP10			ENSG00000105793	NA	NA	rs42648-A	rs42648	0	42648	intron_variant	0	0.4	2e-08	7.69897000433602		0.0395	[0.026-0.053] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	10p13	10	17114152	CUBN	CUBN			ENSG00000107611	NA	NA	rs1801222-A	rs1801222	0	1801222	missense_variant	0	0.34	8e-10	9.09691001300806		0.0453	[0.032-0.059] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	12q24.31	12	120967323	HNF1A	HNF1A-AS1			ENSG00000241388	NA	NA	rs2251468-A	rs2251468	0	2251468	intron_variant	0	0.65	1e-12	12		0.0512	[0.037-0.065] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	19q13.33	19	48756272	FUT2	FGF21			ENSG00000105550	NA	NA	rs838133-A	rs838133	0	838133	synonymous_variant	0	0.45	7e-09	8.15490195998574		0.0422	[0.028-0.056] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	1p36.22	1	11778589	MTHFR	AL953897.1, C1orf167			ENSG00000177553, ENSG00000215910	NA	NA	rs12134663-A	rs12134663	0	12134663	intron_variant	0	0.8	3e-21	20.5228787452803		0.101	[0.079-0.123] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	10p13	10	17181245	CUBN	TRDMT1			ENSG00000107614	NA	NA	rs12780845-A	rs12780845	0	12780845	intron_variant	0	0.65	8e-10	9.09691001300806		0.0529	[0.035-0.071] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	11q14.3	11	89468459	NOX4	NOX4			ENSG00000086991	NA	NA	rs957140-A	rs957140	0	957140	intron_variant	0	0.45	2e-08	7.69897000433602		0.045	[0.029-0.061] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	16q24.3	16	89793345	FANCA, DPEP1	FANCA			ENSG00000187741	NA	NA	rs12921383-T	rs12921383	0	12921383	intron_variant	0	0.87	8e-11	10.0969100130081		0.09	[0.063-0.117] unit decrease	Affymetrix, Illumina [2090256] (imputed)	N
2014-01-31	23824729	van Meurs JB	2013-07-03	Am J Clin Nutr	www.ncbi.nlm.nih.gov/pubmed/23824729	Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.	Homocysteine levels	44,147 European ancestry individuals	NA	21q22.3	21	43067294	CBS	CBS			ENSG00000160200	NA	NA	rs2851391-T	rs2851391	0	2851391	intron_variant	0	0.47	2e-12	11.698970004336		0.056	[0.04-0.072] unit increase	Affymetrix, Illumina [2090256] (imputed)	N
2013-05-09	23376709	Kerns SL	2013-01-31	J Urol	www.ncbi.nlm.nih.gov/pubmed/23376709	A 2-stage genome-wide association study to identify single nucleotide polymorphisms associated with development of urinary symptoms after radiotherapy for prostate cancer.	Urinary symptoms in response to radiotherapy in prostate cancer	346 European, African, Hispanic and Asian ancestry individuals	377 European, African, Hispanic and Asian ancestry individuals	9p21.2	9	27488094	IFNK, MOB3B	MOB3B			ENSG00000120162	NA	NA	rs17779457-?	rs17779457	0	17779457	intron_variant	0	0.25	7e-07	6.15490195998574	(at 2-3 yrs)	2.4	[1.1-3.6] unit increase	Affymetrix [613496]	N
2011-12-14	22087292	Sun L	2011-11-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22087292	Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass.	Femoral neck bone geometry	1,627 Han Chinese ancestry individuals	2,286 European ancestry individuals	2p12	2	74847840	HK2	HK2			ENSG00000159399	NA	NA	rs681900-?	rs681900	0	681900	intron_variant	0	NR	3e-06	5.52287874528034	(ALM-BR)	NA		Affymetrix [689368]	N
2011-12-14	22087292	Sun L	2011-11-07	PLoS One	www.ncbi.nlm.nih.gov/pubmed/22087292	Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass.	Femoral neck bone geometry	1,627 Han Chinese ancestry individuals	2,286 European ancestry individuals	16p12.3	16	20339909	UMOD	UMOD			ENSG00000169344	NA	NA	rs11859916-?	rs11859916	0	11859916	intron_variant	0	NR	2e-06	5.69897000433602	(ALM-W)	NA		Affymetrix [689368]	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	6p21.33	6	31356108	HLA-B, MICA, HCP5, HCG26	HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs41549217-T	rs41549217	0	41549217	non_coding_transcript_exon_variant	0	0.0288	2e-07	6.69897000433602		4.6582	[4.08-5.24]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	14q31.1	14	82806309	intergenic	AL355095.1 - AL359238.1	ENSG00000258683	ENSG00000258600		10088	210797	rs148071215-A	rs148071215	0	148071215	intergenic_variant	1	0.0217	4e-07	6.39794000867204		4.3652	[3.80-4.93]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	8p23.1	8	8642006	intergenic	RN7SL178P - AC087269.3	ENSG00000284857	ENSG00000286910		59351	23491	rs111703385-A	rs111703385	0	111703385	intergenic_variant	1	0.0419	6e-07	6.22184874961636		3.6248	[3.12-4.13]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	2p25.2	2	5999574	LOC150622, LOC400940	SILC1			ENSG00000232044	NA	NA	rs12993904-G	rs12993904	0	12993904	intron_variant	0	0.4783	9e-07	6.04575749056067		1.93	[1.67-2.19]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	15q21.3	15	56403547	RFX7, TEX9, MNS1	TEX9			ENSG00000151575	NA	NA	rs144803255-A	rs144803255	0	144803255	intron_variant	0	0.0241	9e-07	6.04575749056067		4.1709	[3.60-4.74]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	19p13.13	19	12951613	DNASE2, KLF1, GCDH, SYCE2, FARSA, CALR, RAD23A, GADD45GIP1, DAND5, NFIX	RAD23A			ENSG00000179262	NA	NA	rs45495792-G	rs45495792	0	45495792	intron_variant	0	0.1706	1e-06	6		2.11	[1.81-2.41]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	12q13.11	12	48679011	KANSL2, SNORA34, MIR1291, SNORA2A, SNORA2B, CCNT1, LOC255411, ADCY6, MIR4701	KANSL2			ENSG00000139620	NA	NA	rs118067775-C	rs118067775	0	118067775	intron_variant	0	0.0348	1e-06	6		4.12	[3.55-4.69]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1q25.3	1	183286773	LAMC1, LAMC2, NMNAT2	NMNAT2			ENSG00000157064	NA	NA	rs41314643-C	rs41314643	0	41314643	missense_variant	0	0.0159	1e-06	6		5.2714815	[4.6-5.95]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1p33	1	47227548	CYP4A22, LINC00853, PDZK1IP1, TAL1, STIL	AL135960.1, TAL1			ENSG00000226252, ENSG00000162367	NA	NA	rs11211480-G	rs11211480	0	11211480	non_coding_transcript_exon_variant	0	0.5253	2e-06	5.69897000433602		1.9278966	[1.66-2.2]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1p22.3	1	86241900	COL24A1	COL24A1 - LINC02795	ENSG00000171502	ENSG00000285210		84957	46804	rs61800638-G	rs61800638	0	61800638	intergenic_variant	1	0.0438	2e-06	5.69897000433602		3.387534	[2.88-3.89]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	3p22.1	3	42852935	CCDC13, HIGD1A, CCBP2, CYP8B1, ZNF662, KRBOX1, FAM198A	ACKR2, AC092042.3, KRBOX1, AC099329.2			ENSG00000144648, ENSG00000273291, ENSG00000240747, ENSG00000273328	NA	NA	rs10865924-G	rs10865924	0	10865924	intron_variant	0	0.3018	3e-06	5.52287874528034		1.84	[1.59-2.09]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	12q24.32	12	128016467	intergenic	LINC00508 - LINC02441	ENSG00000256971	ENSG00000256643		32613	7321	rs12809497-C	rs12809497	0	12809497	intergenic_variant	1	0.4449	4e-06	5.39794000867204		2.09	[1.78-2.40]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	10p13	10	15171101	RPP38, NMT2, PPIAP30, FAM171A1	AL590365.1			ENSG00000228181	NA	NA	rs17156371-A	rs17156371	0	17156371	non_coding_transcript_exon_variant	0	0.1115	5e-06	5.30102999566398		2.1463	[1.82-2.47]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	5q14.2	5	83114977	TMEM167A, XRCC4	XRCC4			ENSG00000152422	NA	NA	rs114397494-G0.0414	rs114397494	0	114397494	intron_variant	0	0.0414	5e-06	5.30102999566398		2.96	[2.49-3.43]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1p31.2	1	69092456	intergenic	LINC01707			ENSG00000223883	NA	NA	rs3123012-T	rs3123012	0	3123012	intron_variant	0	0.0901	5e-06	5.30102999566398		2.3069	[1.95-2.67]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	12q21.32	12	88254303	C12orf50, C12orf29, CEP290, TMTC3	TMTC3 - Y_RNA	ENSG00000139324	ENSG00000265852		54416	176139	rs112511621-T	rs112511621	0	112511621	intergenic_variant	1	0.1762	6e-06	5.22184874961636		2.4087	[2.03-2.79]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	20q13.12	20	44166408	JPH2, C20orf111, LOC100505783	JPH2			ENSG00000149596	NA	NA	rs62204504-C	rs62204504	0	62204504	intron_variant	0	0.0355	6e-06	5.22184874961636		3.22	[2.71-3.73]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	2p14	2	63980311	UGP2, VPS54	VPS54			ENSG00000143952	NA	NA	rs6546043-A	rs6546043	0	6546043	intron_variant	0	0.7116	7e-06	5.15490195998574		2.079	[1.76-2.40]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	3p14.1	3	64926476	ADAMTS9-AS2, MIR548A2	ADAMTS9-AS2			ENSG00000241684	NA	NA	rs10510921-G	rs10510921	0	10510921	intron_variant	0	0.02	7e-06	5.15490195998574		3.52	[2.97-4.07]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	13q32.2	13	98214742	FARP1, RNF113B, MIR3170	FARP1			ENSG00000152767	NA	NA	rs9513373-C	rs9513373	0	9513373	intron_variant	0	0.02	8e-06	5.09691001300806		4.18	[3.55-4.81]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	8p22	8	16825237	intergenic	AC011586.2			ENSG00000253496	NA	NA	rs73201717-T	rs73201717	0	73201717	intron_variant	0	0.159	8e-06	5.09691001300806		2.08	[1.76-2.40]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1q32.3	1	211918606	INTS7	LPGAT1-AS1 - AC092814.2	ENSG00000229258	ENSG00000233626		64903	17643	rs2808382-C	rs2808382	0	2808382	regulatory_region_variant	1	0.0469	8e-06	5.09691001300806		2.7742	[2.33-3.22]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	3q21.3	3	127359497	intergenic	LINC02016			ENSG00000244215	NA	NA	rs7428297-T	rs7428297	0	7428297	intron_variant	0	0.125	8e-06	5.09691001300806		2.0602	[1.74-2.38]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1q32.1	1	203195061	MYBPH, ADORA1, CHI3L1, CHIT1	CHI3L1 - CHIT1	ENSG00000133048	ENSG00000133063		8357	17766	rs115384187-A	rs115384187	0	115384187	intergenic_variant	1	0.0125	9e-06	5.04575749056067		6.4585	[5.64-7.28]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	19q13.42	19	54660297	LILRB1, LILRB4, LILRP2	LILRB4, LILRB4, LILRB4, LILRB4			ENSG00000186818, ENSG00000276042, ENSG00000278555, ENSG00000275730	NA	NA	rs425283-A	rs425283	0	425283	intron_variant	0	0.1616	9e-06	5.04575749056067		1.9644	[1.67-2.26]	Illumina [8809853] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	4q12	4	56467946	SRP72	SRP72			ENSG00000174780	NA	NA	rs12505749-?	rs12505749	0	12505749	intron_variant	0	0.08	5e-06	5.30102999566398	(All)	1.27		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	22q12.1	22	26257396	SEZ6L	SEZ6L			ENSG00000100095	NA	NA	rs1207393-?	rs1207393	0	1207393	intron_variant	0	0.64	5e-06	5.30102999566398	(FEV1 65%)	1.19		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	4q24	4	106079305	MGC16169	TBCK			ENSG00000145348	NA	NA	rs11097912-?	rs11097912	0	11097912	intron_variant	0	0.67	6e-06	5.22184874961636	(smokers)	1.18		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	18q22.3	18	72559786	CBLN	CBLN2			ENSG00000141668	NA	NA	rs17086172-?	rs17086172	0	17086172	intron_variant	0	0.06	7e-06	5.15490195998574	(no asthma)	1.35		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	17q25.3	17	77404018	SEPT9	SEPTIN9, SEPTIN9			ENSG00000184640, ENSG00000282302	NA	NA	rs892961-?	rs892961	0	892961	intron_variant	0	0.59	9e-06	5.04575749056067	(no asthma)	1.18		Affymetrix, Illumina [up to 2500000] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19p13.3	19	5841345	FUT6	FUT6 - FUT3	ENSG00000156413	ENSG00000171124		1614	1543	rs3760775-T	rs3760775	0	3760775	regulatory_region_variant	1	0.33	1e-35	35	(CEA)	0.073	[0.048-0.098] ng/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19q13.33	19	48703374	FUT2, CA11	FUT2			ENSG00000176920	NA	NA	rs1047781-T	rs1047781	0	1047781	missense_variant	0	0.46	8e-176	175.096910013008	(CA19-9)	0.444	[0.41-0.48] U/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19p13.3	19	5834201	FUT6	FUT6			ENSG00000156413	NA	NA	rs17271883-G	rs17271883	0	17271883	intron_variant	0	0.38	5e-132	131.301029995664	(CA19-9)	0.282	[0.20-0.37] U/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19p13.3	19	5839735	FUT6	FUT6 - FUT3	ENSG00000156413	ENSG00000171124		4	3153	rs3760776-T	rs3760776	0	3760776	TF_binding_site_variant	1	0.20	2e-56	55.698970004336	(CA19-9)	0.169	[0.11-0.22] U/ml decrease	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19p13.3	19	5841345	FUT6	FUT6 - FUT3	ENSG00000156413	ENSG00000171124		1614	1543	rs3760775-T	rs3760775	0	3760775	regulatory_region_variant	1	0.33	3e-290	289.52287874528	(CA19-9)	0.481	[0.44-0.52] U/ml decrease	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19p13.11	19	17791525	B3GNT3	FCHO1 - B3GNT3	ENSG00000130475	ENSG00000179913		2957	3303	rs265548-C	rs265548	0	265548	intergenic_variant	1	0.26	1e-13	13	(CA19-9)	0.072	[0.029-0.115] U/ml decrease	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	9q34.2	9	133255801	ABO	ABO, ABO			ENSG00000175164, ENSG00000281879	NA	NA	rs8176749-T	rs8176749	0	8176749	synonymous_variant	0	0.18	7e-105	104.154901959986	(CEA)	0.205	[0.18-0.23] ng/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	19q13.33	19	48703374	FUT2	FUT2			ENSG00000176920	NA	NA	rs1047781-T	rs1047781	0	1047781	missense_variant	0	0.46	6e-209	208.221848749616	(CEA)	0.238	[0.21-0.26] ng/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	21q22.3	21	41326980	FAM3B	FAM3B			ENSG00000183844	NA	NA	rs441810-G	rs441810	0	441810	intron_variant	0	0.24	3e-22	21.5228787452803	(CEA)	0.069	[0.040-0.098] ng/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	4q13.3	4	73453566	AFP	AFP			ENSG00000081051	NA	NA	rs12506899-G	rs12506899	0	12506899	non_coding_transcript_exon_variant	0	0.32	3e-18	17.5228787452803	(AFP)	0.065	[0.032-0.098] ng/ml decrease	Affymetrix, Illumina [NR] (imputed)	N
2013-04-11	23300138	He M	2013-01-07	Gut	www.ncbi.nlm.nih.gov/pubmed/23300138	A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk.	Tumor biomarkers	3,451 Han Chinese ancestry individuals	10,326 Chinese ancestry individuals	15q15.3	15	43544280	HISPPD2A	PPIP5K1			ENSG00000168781	NA	NA	rs2251844-C	rs2251844	0	2251844	intron_variant	0	0.42	1e-14	14	(AFP)	0.087	[0.056-0.118] ng/ml increase	Affymetrix, Illumina [NR] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	5p14.1	5	26746274	intergenic	AC113347.4			ENSG00000251033	NA	NA	rs116688600-C	rs116688600	0	116688600	intron_variant	0	0.0196	9e-06	5.04575749056067		5.07	[4.35-5.79]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	7q21.11	7	85937160	intergenic	AC092013.1 - SOCS5P1	ENSG00000227785	ENSG00000236610		300816	279625	rs17312438-C	rs17312438	0	17312438	intergenic_variant	1	0.0116	9e-06	5.04575749056067		8.37	[7.43-9.31]	Illumina [8809853] (imputed)	N
2015-06-27	25187353	Goldstein JI	2014-09-04	Nat Commun	www.ncbi.nlm.nih.gov/pubmed/25187353	Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.	Clozapine-induced agranulocytosis	161 European ancestry cases, 1,196 European ancestry clozapine-treated and untreated controls	NA	1q32.1	1	204948452	NFASC	NFASC			ENSG00000163531	NA	NA	rs2068666-G	rs2068666	0	2068666	intron_variant	0	0.0813	9e-06	5.04575749056067		2.38	[2.00-2.76]	Illumina [8809853] (imputed)	N
2013-09-07	23642732	Cox AJ	2013-04-19	Atherosclerosis	www.ncbi.nlm.nih.gov/pubmed/23642732	Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.	Bilirubin levels	1,180 European ancestry individuals from ~475 families		2q37.1	2	233759924	UGT1A	UGT1A6, UGT1A3, UGT1A9, UGT1A7, UGT1A4, UGT1A5, UGT1A10, UGT1A8			ENSG00000167165, ENSG00000243135, ENSG00000241119, ENSG00000244122, ENSG00000244474, ENSG00000240224, ENSG00000242515, ENSG00000242366	NA	NA	rs887829-T	rs887829	0	887829	intron_variant	0	0.312	9e-20	19.0457574905607		NA		Affymetrix, Illumina [371951]	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1q25.2	1	177883445	SEC16B	AL136114.1			ENSG00000227579	NA	NA	rs633715-C	rs633715	0	633715	intron_variant	0	0.19	4e-19	18.397940008672	(Obesity class II)	1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	4p12	4	45173674	GNPDA2	AC108467.1 - THAP12P9	ENSG00000248744	ENSG00000248320		122022	149579	rs13130484-T	rs13130484	0	13130484	intergenic_variant	1	0.43	3e-18	17.5228787452803	(Obesity class II)	1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	12q13.12	12	49853685	LOC144233	BCDIN3D - AC131157.1	ENSG00000186666	ENSG00000257253		10579	7522	rs7138803-A	rs7138803	0	7138803	intergenic_variant	1	0.38	1e-16	16	(Obesity class II)	1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p31.1	1	72285502	NEGR1	AL513166.1			ENSG00000286863	NA	NA	rs3101336-C	rs3101336	0	3101336	intron_variant	0	0.61	1e-13	13	(Obesity class II)	1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	19q13.32	19	45679046	GIPR	GIPR			ENSG00000010310	NA	NA	rs10423928-T	rs10423928	0	10423928	intron_variant	0	0.77	4e-13	12.397940008672	(Obesity class II)	1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	11p14.1	11	27706992	BDNF	BDNF, AC103796.1			ENSG00000176697, ENSG00000255496	NA	NA	rs2030323-C	rs2030323	0	2030323	intron_variant	0	0.79	6e-11	10.2218487496164	(Obesity class II)	1.13	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	9p21.1	9	28425517	LINGO2	LINGO2			ENSG00000174482	NA	NA	rs1412239-G	rs1412239	0	1412239	intron_variant	0	0.32	2e-10	9.69897000433602	(Obesity class II)	1.11	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	13q14.3	13	53533217	OLFM4	AL356295.1			ENSG00000287722	NA	NA	rs9568867-A	rs9568867	0	9568867	intron_variant	0	0.13	2e-09	8.69897000433602	(Obesity class II)	1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	3q27.2	3	186106215	ETV5	DGKG, ETV5			ENSG00000058866, ENSG00000244405	NA	NA	rs1516725-C	rs1516725	0	1516725	intron_variant	0	0.86	3e-09	8.52287874528034	(Obesity class II)	1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	5q13.3	5	75719417	C5orf37	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078		1969	33153	rs2112347-T	rs2112347	0	2112347	intergenic_variant	1	0.63	4e-09	8.39794000867204	(Obesity class II)	1.09	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p12.3	16	19933041	GPRC5B	GPRC5B - GPR139	ENSG00000167191	ENSG00000180269		46874	98444	rs11639988-A	rs11639988	0	11639988	intergenic_variant	1	0.86	4e-09	8.39794000867204	(Obesity class II)	1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p16.1	2	59075742	FANCL	AC007092.1			ENSG00000285673	NA	NA	rs887912-T	rs887912	0	887912	intron_variant	0	0.28	6e-09	8.22184874961636	(Obesity class II)	1.1	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p11.2	16	28910488	RABEP2, SH2B1	RABEP2			ENSG00000177548	NA	NA	rs7184597-T	rs7184597	0	7184597	non_coding_transcript_exon_variant	0	0.33	7e-09	8.15490195998574	(Obesity class II)	1.1	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16q12.2	16	53767042	FTO	FTO			ENSG00000140718	NA	NA	rs1421085-C	rs1421085	0	1421085	intron_variant	0	0.41	6e-39	38.2218487496164	(Obesity class III)	1.45	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p31.1	1	77582646	ZZZ3	AC118549.1			ENSG00000036549	NA	NA	rs17381664-C	rs17381664	0	17381664	intron_variant	0	0.39	3e-08	7.52287874528034	(Obesity class II)	1.09	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p13.3	1	109604699	GNAT2	GNAT2, GNAI3			ENSG00000134183, ENSG00000065135	NA	NA	rs17024258-T	rs17024258	0	17024258	3_prime_UTR_variant	0	0.04	9e-12	11.0457574905607	(Obesity class I)	1.25	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	8q21.13	8	75703428	HNF4G	HNF4G - AC011029.1	ENSG00000164749	ENSG00000287352		136594	458691	rs4735692-A	rs4735692	0	4735692	intergenic_variant	1	0.58	2e-09	8.69897000433602	(Obesity class I)	1.06	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	20q13.2	20	52476457	MRPS33P4	LINC01524			ENSG00000234948	NA	NA	rs13041126-T	rs13041126	0	13041126	intron_variant	0	0.72	2e-08	7.69897000433602	(Obesity class I)	1.06	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p13.3	16	3963466	ADCY9	ADCY9			ENSG00000162104	NA	NA	rs2531995-T	rs2531995	0	2531995	3_prime_UTR_variant	0	0.61	4e-08	7.39794000867204	(Obesity class I)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16q12.2	16	53779538	FTO	FTO			ENSG00000140718	NA	NA	rs8043757-T	rs8043757	0	8043757	intron_variant	0	0.4	5e-110	109.301029995664	(Obesity class I)	1.23	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p25.3	2	624034	TMEM18	AC093326.1 - TMEM18	ENSG00000233633	ENSG00000151353		45889	39843	rs6711012-C	rs6711012	0	6711012	intergenic_variant	1	0.82	3e-40	39.5228787452803	(Obesity class I)	1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	18q21.32	18	60183189	MC4R	RNU4-17P - AC090771.1	ENSG00000202468	ENSG00000267620		19482	13366	rs538656-T	rs538656	0	538656	intergenic_variant	1	0.24	2e-36	35.698970004336	(Obesity class I)	1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	4p12	4	45180510	GNPDA2	AC108467.1 - THAP12P9	ENSG00000248744	ENSG00000248320		128858	142743	rs10938397-G	rs10938397	0	10938397	intergenic_variant	1	0.43	3e-34	33.5228787452803	(Obesity class I)	1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1q25.2	1	177883445	SEC16B	AL136114.1			ENSG00000227579	NA	NA	rs633715-C	rs633715	0	633715	intron_variant	0	0.19	9e-23	22.0457574905607	(Obesity class I)	1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	11p14.1	11	27706992	BDNF	BDNF, AC103796.1			ENSG00000176697, ENSG00000255496	NA	NA	rs2030323-C	rs2030323	0	2030323	intron_variant	0	0.79	3e-22	21.5228787452803	(Obesity class I)	1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	6p12.3	6	50830813	TFAP2B	TFAP2B			ENSG00000008196	NA	NA	rs2206277-T	rs2206277	0	2206277	intron_variant	0	0.18	5e-22	21.301029995664	(Obesity class I)	1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	12q13.12	12	49853685	LOC144233	BCDIN3D - AC131157.1	ENSG00000186666	ENSG00000257253		10579	7522	rs7138803-A	rs7138803	0	7138803	intergenic_variant	1	0.38	1e-20	20	(Obesity class I)	1.09	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p23.3	2	24927427	ADCY3, POMC	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137		7588	16209	rs10182181-G	rs10182181	0	10182181	intergenic_variant	1	0.46	1e-17	17	(Obesity class I)	1.08	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	14q31.1	14	79433111	NRXN3	NRXN3			ENSG00000021645	NA	NA	rs7141420-T	rs7141420	0	7141420	intron_variant	0	0.52	1e-17	17	(Obesity class I)	1.08	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p31.1	1	72371556	NEGR1	AL513166.1			ENSG00000286863	NA	NA	rs7531118-C	rs7531118	0	7531118	intron_variant	0	0.56	2e-17	16.698970004336	(Obesity class I)	1.08	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	19q13.32	19	45678134	GIPR	GIPR			ENSG00000010310	NA	NA	rs1800437-G	rs1800437	0	1800437	missense_variant	0	0.78	3e-14	13.5228787452803	(Obesity class I)	1.1	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p11.2	16	28871920	SH2B1	SH2B1			ENSG00000178188	NA	NA	rs7498665-G	rs7498665	0	7498665	missense_variant	0	0.4	3e-13	12.5228787452803	(Obesity class I)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	15q23	15	67750719	MAP2K5	MAP2K5			ENSG00000137764	NA	NA	rs8028313-C	rs8028313	0	8028313	intron_variant	0	0.78	6e-13	12.2218487496164	(Obesity class I)	1.08	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	5q13.3	5	75707853	C5orf37	POC5			ENSG00000152359	NA	NA	rs2307111-T	rs2307111	0	2307111	missense_variant	0	0.6	3e-12	11.5228787452803	(Obesity class I)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p16.1	2	59075742	FANCL	AC007092.1			ENSG00000285673	NA	NA	rs887912-T	rs887912	0	887912	intron_variant	0	0.28	1e-10	10	(Obesity class I)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p12.3	16	19924067	GPRC5B	GPRC5B - GPR139	ENSG00000167191	ENSG00000180269		37900	107418	rs12446632-G	rs12446632	0	12446632	intergenic_variant	1	0.86	2e-10	9.69897000433602	(Obesity class I)	1.09	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	9p21.1	9	28414341	LINGO2	LINGO2			ENSG00000174482	NA	NA	rs10968576-G	rs10968576	0	10968576	intron_variant	0	0.32	3e-08	7.52287874528034	(Obesity class I)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16q12.2	16	53788739	FTO	FTO			ENSG00000140718	NA	NA	rs7185735-G	rs7185735	0	7185735	intron_variant	0	0.4	1e-79	79	(Obesity class II)	1.33	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p25.3	2	646364	TMEM18	AC093326.1 - TMEM18	ENSG00000233633	ENSG00000151353		68219	17513	rs10189761-A	rs10189761	0	10189761	intergenic_variant	1	0.82	6e-24	23.2218487496164	(Obesity class II)	1.24	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	13q32.1	13	96365294	HS6ST3	HS6ST3			ENSG00000185352	NA	NA	rs7989336-A	rs7989336	0	7989336	intron_variant	0	0.47	1e-08	8	(Obesity class II)	1.1	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	6p12.3	6	50877777	TFAP2B	RPS17P5 - AL049693.1	ENSG00000060303	ENSG00000216913		20115	19838	rs2207139-G	rs2207139	0	2207139	intergenic_variant	1	0.18	3e-19	18.5228787452803	(Obesity class II)	1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	3q27.2	3	186116710	ETV5	DGKG			ENSG00000058866	NA	NA	rs9816226-T	rs9816226	0	9816226	intron_variant	0	0.82	2e-13	12.698970004336	(Obesity class I)	1.1	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	11p15.4	11	8640969	RPL27A	TRIM66			ENSG00000166436	NA	NA	rs11042023-C	rs11042023	0	11042023	missense_variant	0	0.65	1e-11	11	(Obesity class I)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p31.1	1	74525718	TNNI3K	TNNI3K, FPGT-TNNI3K			ENSG00000116783, ENSG00000259030	NA	NA	rs1514177-C	rs1514177	0	1514177	intron_variant	0	0.43	5e-09	8.30102999566398	(Obesity class I)	1.06	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	18q21.32	18	60185715	MC4R	RNU4-17P - AC090771.1	ENSG00000202468	ENSG00000267620		22008	10840	rs11152213-C	rs11152213	0	11152213	intergenic_variant	1	0.24	3e-22	21.5228787452803	(Obesity class II)	1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	8q21.13	8	75703428	HNF4G	HNF4G - AC011029.1	ENSG00000164749	ENSG00000287352		136594	458691	rs4735692-A	rs4735692	0	4735692	intergenic_variant	1	0.58	4e-10	9.39794000867204	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	17q25.3	17	80617311	RPTOR	RPTOR			ENSG00000141564	NA	NA	rs7503807-A	rs7503807	0	7503807	intron_variant	0	0.57	2e-08	7.69897000433602	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16q12.2	16	53769662	FTO	FTO			ENSG00000140718	NA	NA	rs1558902-A	rs1558902	0	1558902	intron_variant	0	0.41	2e-81	80.698970004336	(Overweight)	1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p25.3	2	624034	TMEM18	AC093326.1 - TMEM18	ENSG00000233633	ENSG00000151353		45889	39843	rs6711012-C	rs6711012	0	6711012	intergenic_variant	1	0.82	6e-35	34.2218487496164	(Overweight)	1.11	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	4p12	4	45173674	GNPDA2	AC108467.1 - THAP12P9	ENSG00000248744	ENSG00000248320		122022	149579	rs13130484-T	rs13130484	0	13130484	intergenic_variant	1	0.43	4e-28	27.397940008672	(Overweight)	1.08	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	3p14.2	3	62126467	PTPRG, ID2B	PTPRG			ENSG00000144724	NA	NA	rs35593266-A	rs35593266	0	35593266	intron_variant	0		5e-06	5.30102999566398		0.2196	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	3q21.2	3	125874014	intergenic	LINC02614, ENPP7P4			ENSG00000241288, ENSG00000241278	NA	NA	rs71327718-G	rs71327718	0	71327718	intron_variant	0		7e-06	5.15490195998574		0.2152	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	5p13.2	5	35461098	intergenic	U3 - SPEF2	ENSG00000202268	ENSG00000152582		31821	156746	rs284737-C	rs284737	0	284737	intergenic_variant	1		8e-06	5.09691001300806		0.2134	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	6q25.1	6	150059748	ULBP3	PHBP1 - ULBP3	ENSG00000213091	ENSG00000131019		16395	1305	rs78546022-G	rs78546022	0	78546022	intergenic_variant	1		4e-06	5.39794000867204		0.2221	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	8p12	8	29248542	KIF13B	KIF13B			ENSG00000197892	NA	NA	rs2954793-T	rs2954793	0	2954793	intron_variant	0	NR	3e-06	5.52287874528034		0.2305	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	8q22.1	8	95093809	C8orf38	NDUFAF6			ENSG00000156170	NA	NA	rs4590408-G	rs4590408	0	4590408	intron_variant	0	NR	6e-06	5.22184874961636		0.2245	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	9p22.1	9	19213636	DQ572382	AL161909.1 - DENND4C	ENSG00000232176	ENSG00000137145		12590	16799	rs141215807-T	rs141215807	0	141215807	intergenic_variant	1	NR	9e-06	5.04575749056067		0.222	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	9q33.3	9	127348132	GARNL3, SLC2A8	GARNL3			ENSG00000136895	NA	NA	rs7029536-T	rs7029536	0	7029536	intron_variant	0	NR	5e-06	5.30102999566398		0.2261	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	12q13.11	12	47421189	intergenic	LINC02156 - ADI1P3	ENSG00000257906	ENSG00000258369		997	41898	rs1881744-A	rs1881744	0	1881744	intergenic_variant	1		2e-06	5.69897000433602		0.228	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	12q23.1	12	99510762	ANKS1B	ANKS1B			ENSG00000185046	NA	NA	rs1961649-T	rs1961649	0	1961649	intron_variant	0		3e-06	5.52287874528034		0.2234	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	6q27	6	167988248	HGC6.1.1, MLLT4, KIF25, HGC6.3	HGC6.3 - KIF25-AS1	ENSG00000235994	ENSG00000229921		8472	4574	rs2843012-A	rs2843012	0	2843012	regulatory_region_variant	1	NR	6e-06	5.22184874961636		0.218	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	1q41	1	222071916	intergenic	LINC01705 - AL356108.1	ENSG00000232679	ENSG00000236230		7143	16890	rs10863681-G	rs10863681	0	10863681	regulatory_region_variant	1		6e-06	5.22184874961636		0.2262	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	8p23.2	8	6295398	intergenic	AC009435.1 - AC016065.1	ENSG00000253880	ENSG00000246089		37861	108153	rs6559140-A	rs6559140	0	6559140	intergenic_variant	1	NR	7e-06	5.15490195998574		0.2159	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	8q24.13	8	121694051	intergenic	LINC02855, HAS2-AS1			ENSG00000254209, ENSG00000248690	NA	NA	rs279612-G	rs279612	0	279612	intron_variant	0	NR	7e-06	5.15490195998574		0.2138	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	9q21.13	9	76050860	PCSK5	PCSK5			ENSG00000099139	NA	NA	rs7047865-G	rs7047865	0	7047865	intron_variant	0	NR	5e-06	5.30102999566398		0.2188	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	4q22.1	4	90480460	FAM190A	CCSER1			ENSG00000184305	NA	NA	rs187200046-T	rs187200046	0	187200046	intron_variant	0		4e-06	5.39794000867204		0.2293	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	13q31.3	13	91080516	intergenic	BRK1P2 - LINC00380	ENSG00000227983	ENSG00000234625		56562	6738	rs61970269-T	rs61970269	0	61970269	intergenic_variant	1	NR	3e-06	5.52287874528034		0.2234	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	16q23.1	16	78301147	WWOX	WWOX			ENSG00000186153	NA	NA	rs78867184-G	rs78867184	0	78867184	intron_variant	0	NR	9e-06	5.04575749056067		0.213	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	17p13.3	17	2241899	SMG6, SRR, AJ276246	SMG6			ENSG00000070366	NA	NA	rs11078884-C	rs11078884	0	11078884	intron_variant	0	NR	3e-06	5.52287874528034		0.2234	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	8p12	8	29137505	KIF13B, AF086219	AC108449.1, KIF13B			ENSG00000254129, ENSG00000197892	NA	NA	rs13251954-A	rs13251954	0	13251954	intron_variant	0		2e-06	5.69897000433602		0.2357	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	1q31.1	1	187442910	intergenic	ERVMER61-1			ENSG00000230426	NA	NA	rs2244067-T	rs2244067	0	2244067	intron_variant	0	NR	7e-06	5.15490195998574		0.2142	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	8q22.1	8	95093809	C8orf38	NDUFAF6			ENSG00000156170	NA	NA	rs4590408-G	rs4590408	0	4590408	intron_variant	0		6e-06	5.22184874961636		0.2255	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	2q22.1	2	138641784	intergenic	LINC02631 - NXPH2	ENSG00000237772	ENSG00000144227		24315	27373	rs58938945-A	rs58938945	0	58938945	regulatory_region_variant	1		8e-06	5.09691001300806		0.2848	unit increase	Illumina [5767231] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	21q21.3	21	26344335	CYYR1	AP001595.2 - AP001595.1	ENSG00000286902	ENSG00000229025		23562	5445	rs9975851-T	rs9975851	0	9975851	intergenic_variant	1	0.57	4e-06	5.39794000867204	(No asthma)	1.17	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	5q32	5	148476770	HTR4	HTR4			ENSG00000164270	NA	NA	rs7733088-?	rs7733088	0	7733088	intron_variant	0	0.62	4e-09	8.39794000867204	(Smoker)	1.2346	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	9p23	9	9910123	PTPRD	PTPRD			ENSG00000153707	NA	NA	rs10759102-?	rs10759102	0	10759102	intron_variant	0	0.67	1e-06	6	(FEV1 65%)	1.23	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	13q12.12	13	24221351	SPATA13	SPATA13, AL359736.1			ENSG00000182957, ENSG00000273167	NA	NA	rs715921-A	rs715921	0	715921	intron_variant	0	0.31	8e-07	6.09691001300806	(No asthma)	1.2	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	6p22.3	6	24306159	DCDC2	DCDC2			ENSG00000146038	NA	NA	rs16889038-?	rs16889038	0	16889038	intron_variant	0	0.08	8e-07	6.09691001300806	(FEV1 65%)	1.3889	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	3p24.2	3	25496826	RARB	RARB			ENSG00000077092	NA	NA	rs1997352-?	rs1997352	0	1997352	intron_variant	0	0.74	9e-07	6.04575749056067	(All)	1.1905	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	3p26.1	3	4591808	ITPR1	ITPR1			ENSG00000150995	NA	NA	rs2322734-?	rs2322734	0	2322734	intron_variant	0	0.04	8e-06	5.09691001300806	(FEV1 65%)	1.4493	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	2q37.3	2	236613199	CXCR7	ACKR3 - AC084030.1	ENSG00000144476	ENSG00000232328		30845	120090	rs7607316-A	rs7607316	0	7607316	intergenic_variant	1	0.21	3e-06	5.52287874528034	(Never smoker)	1.29	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	18q22.1	18	64209921	SERPINB8	LINC01538, LINC01924			ENSG00000266952, ENSG00000267134	NA	NA	rs4534959-?	rs4534959	0	4534959	intron_variant	0	0.03	7e-07	6.15490195998574	(FEV1 65%)	1.7241	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	3q27.2	3	185424069	MAP3K13	MAP3K13			ENSG00000073803	NA	NA	rs7629245-T	rs7629245	0	7629245	intron_variant	0	0.15	9e-06	5.04575749056067	(Smoker)	1.22	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	7p15.1	7	28392857	CREB5	CREB5			ENSG00000146592	NA	NA	rs7799265-?	rs7799265	0	7799265	intron_variant	0	0.05	2e-06	5.69897000433602	(FEV1 65%)	1.5385	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	13q14.3	13	52920559	PCDH8	PCDH8 - OLFM4	ENSG00000136099	ENSG00000102837		71918	108254	rs9536318-?	rs9536318	0	9536318	intergenic_variant	1	0.17	8e-07	6.09691001300806	(No asthma)	1.25	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	12q24.21	12	114200043	TBX5	AC010183.2 - LINC02459	ENSG00000257997	ENSG00000257476		86554	38927	rs4767234-A	rs4767234	0	4767234	intergenic_variant	1	0.59	6e-07	6.22184874961636	(Smoker)	1.17	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	1p32.2	1	55894140	PPAP2B	LINC01755, AL603840.1			ENSG00000233079, ENSG00000234810	NA	NA	rs6684428-A	rs6684428	0	6684428	intron_variant	0	0.16	5e-07	6.30102999566398	(Smoker)	1.23	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	1p31.3	1	68319530	GPR177	COX6B1P7 - ELOCP18	ENSG00000225242	ENSG00000237622		36908	55797	rs11209261-?	rs11209261	0	11209261	intergenic_variant	1	0.24	3e-06	5.52287874528034	(FEV1 65%)	1.2346	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	15q23	15	71387620	THSD4	THSD4			ENSG00000187720	NA	NA	rs2044029-A	rs2044029	0	2044029	intron_variant	0	.4	1e-07	7	(All)	1.17	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	15q24.1	15	74424268	SEMA7A	SEMA7A			ENSG00000138623	NA	NA	rs8036030-?	rs8036030	0	8036030	intron_variant	0	0.61	8e-06	5.09691001300806	(No asthma)	1.1765	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	15q26.1	15	92340610	ST8SIA2	AC116903.2 - ST8SIA2	ENSG00000260661	ENSG00000140557		9573	53271	rs12905014-?	rs12905014	0	12905014	intergenic_variant	1	0.05	4e-07	6.39794000867204	(FEV1 65%)	1.7544	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	10q23.33	10	92409040	IDE	MARCH5 - MARK2P9	ENSG00000198060	ENSG00000232709		55076	9627	rs2263638-?	rs2263638	0	2263638	intergenic_variant	1	0.63	3e-06	5.52287874528034	(Never smoker)	1.2821	[NR]	Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	15q25.1	15	78575140	CHRNA5	CHRNA5			ENSG00000169684	NA	NA	rs17486278-?	rs17486278	0	17486278	intron_variant	0	0.34	2e-07	6.69897000433602	(All)	1.18		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	15q25.1	15	78523715	AGPHD1	HYKK			ENSG00000188266	NA	NA	rs8031948-T	rs8031948	0	8031948	intron_variant	0	0.35	3e-09	8.52287874528034	(Smokers)	1.22		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	10q26.11	10	117620145	EMX2	AL356419.1 - LINC02674	ENSG00000288172	ENSG00000234952		26249	114365	rs181654-?	rs181654	0	181654	intergenic_variant	1	0.72	1e-07	7	(no asthma)	1.23		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	4q25	4	108296773	LEF1	LEF1-AS1 - RPSAP34	ENSG00000232021	ENSG00000239939		38736	111070	rs13144621-?	rs13144621	0	13144621	intergenic_variant	1	0.68	1e-06	6	(All)	1.16		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	7q11.22	7	71923865	CALN1	CALN1			ENSG00000183166	NA	NA	rs11766496-C	rs11766496	0	11766496	intron_variant	0	0.12	2e-06	5.69897000433602	(All)	1.3		Affymetrix, Illumina [up to 2500000] (imputed)	N
2012-09-26	22837378	Wilk JB	2012-07-26	Am J Respir Crit Care Med	www.ncbi.nlm.nih.gov/pubmed/22837378	Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.	Airflow obstruction	up to 3,368 European ancestry cases, up to 29,507 European ancestry controls	331 European ancestry cases, 2,550 European ancestry controls	6q24.2	6	142432201	GPR126	ADGRG6			ENSG00000112414	NA	NA	rs1329705-?	rs1329705	0	1329705	intron_variant	0	0.8	3e-06	5.52287874528034	(FEV1 65%)	1.27		Affymetrix, Illumina [up to 2500000] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	4q22.1	4	90480460	FAM190A	CCSER1			ENSG00000184305	NA	NA	rs187200046-T	rs187200046	0	187200046	intron_variant	0	NR	2e-06	5.69897000433602		0.2366	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	4q34.3	4	180308047	intergenic	AC096747.1 - NDUFB5P1	ENSG00000287775	ENSG00000251025		190884	265417	rs17834666-A	rs17834666	0	17834666	intergenic_variant	1	NR	8e-06	5.09691001300806		0.2201	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	6q15	6	92487582	intergenic	AL133457.1 - AL359987.1	ENSG00000261038	ENSG00000288101		98755	143484	rs13207034-A	rs13207034	0	13207034	intergenic_variant	1	NR	4e-06	5.39794000867204		0.2275	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	9q34.11	9	129587318	BC037833	AL391056.1 - NTMT1	ENSG00000227619	ENSG00000148335		2762	21566	rs73628692-T	rs73628692	0	73628692	regulatory_region_variant	1		7e-06	5.15490195998574		0.2144	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	11p13	11	31863373	RCN1, DKFZp686K1684	PAUPAR, AL035078.4			ENSG00000281880, ENSG00000285283	NA	NA	rs11031492-G	rs11031492	0	11031492	intron_variant	0		4e-06	5.39794000867204		0.2196	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	21q21.3	21	26773870	intergenic	CYYR1 - ADAMTS1	ENSG00000166265	ENSG00000154734		200584	61885	rs2830487-A	rs2830487	0	2830487	intergenic_variant	1	NR	2e-07	6.69897000433602		0.2543	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	21q22.2	21	38349842	ERG	LINC01423 - ERG	ENSG00000231231	ENSG00000157554		16421	30185	rs2836326-G	rs2836326	0	2836326	intergenic_variant	1	NR	3e-06	5.52287874528034		0.2311	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	1q32.3	1	213661300	intergenic	AL592402.1 - AC096639.1	ENSG00000225233	ENSG00000228255		82033	70116	rs4655303-T	rs4655303	0	4655303	regulatory_region_variant	1	NR	5e-06	5.30102999566398		0.2187	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	2p22.3	2	35437731	intergenic	AC079352.1 - MIR548AD	ENSG00000226994	ENSG00000265301		152734	33674	rs13402855-C	rs13402855	0	13402855	regulatory_region_variant	1	NR	2e-06	5.69897000433602		0.2262	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/5-HIAA ratio)	up to 398 European ancestry individuals	NA	16p13.3	16	3719580	TRAP1, CREBBP	TRAP1 - CREBBP	ENSG00000126602	ENSG00000005339		2027	5474	rs56240109-G	rs56240109	0	56240109	intergenic_variant	1		5e-06	5.30102999566398		0.219	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	8p23.2	8	5369580	intergenic	AC007718.1 - AC091193.1	ENSG00000278256	ENSG00000271248		5930	85638	rs77265424-G	rs77265424	0	77265424	regulatory_region_variant	1	NR	4e-06	5.39794000867204		0.2223	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	2p23.3	2	26027030	U6, RAB10	UQCRHP2 - TRMT112P6	ENSG00000237629	ENSG00000268412		31949	1178	rs68184094-A	rs68184094	0	68184094	intergenic_variant	1		4e-06	5.39794000867204		0.2298	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	3p25.3	3	11583940	VGLL4	VGLL4			ENSG00000144560	NA	NA	rs6802119-C	rs6802119	0	6802119	intron_variant	0		8e-06	5.09691001300806		0.2221	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	11q24.3	11	128946326	TP53AIP1, ARHGAP32, 5S_rRNA	TP53AIP1 - ARHGAP32	ENSG00000120471	ENSG00000134909		2927	18734	rs11221522-A	rs11221522	0	11221522	intergenic_variant	1	NR	5e-07	6.30102999566398		0.2412	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	6q15	6	92487582	intergenic	AL133457.1 - AL359987.1	ENSG00000261038	ENSG00000288101		98755	143484	rs13207034-A	rs13207034	0	13207034	intergenic_variant	1		1e-06	6		0.2425	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	6p22.3	6	21454922	intergenic	AL031767.2 - LINC00581	ENSG00000286368	ENSG00000280989		71722	30974	rs9460635-C	rs9460635	0	9460635	intergenic_variant	1		7e-06	5.15490195998574		0.2238	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA)	up to 398 European ancestry individuals	NA	1p35.2	1	30842746	intergenic	LINC01778 - RN7SKP91	ENSG00000223382	ENSG00000222784		7882	1077	rs4949316-G	rs4949316	0	4949316	regulatory_region_variant	1	NR	9e-06	5.04575749056067		0.2127	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	8q13.3	8	70227095	NCOA2	NCOA2			ENSG00000140396	NA	NA	rs72663955-G	rs72663955	0	72663955	intron_variant	0		6e-06	5.22184874961636		0.2246	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	1p36.31	1	5647756	AK125078	AL365255.1			ENSG00000236948	NA	NA	rs4845812-T	rs4845812	0	4845812	intron_variant	0		5e-06	5.30102999566398		0.2917	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	1q32.1	1	203523592	OPTC	OPTC - ATP2B4	ENSG00000188770	ENSG00000058668		14643	102969	rs13303128-C	rs13303128	0	13303128	intergenic_variant	1		9e-06	5.04575749056067		0.2833	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	20q12	20	40810843	intergenic	AL035665.2 - RNA5SP484	ENSG00000286972	ENSG00000238908		52207	43276	rs4812466-T	rs4812466	0	4812466	intergenic_variant	1		6e-06	5.22184874961636		0.2258	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	21q21.3	21	26773870	intergenic	CYYR1 - ADAMTS1	ENSG00000166265	ENSG00000154734		200584	61885	rs2830487-A	rs2830487	0	2830487	intergenic_variant	1		5e-07	6.30102999566398		0.2494	unit increase	Illumina [5767231] (imputed)	N
2013-06-27	23541324	Li X	2013-03-27	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/23541324	Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.	Pulmonary function in asthmatics	1,544 European ancestry individuals		22q13.31	22	45272131	UPK3A	AL008718.2 - AL008718.1	ENSG00000273287	ENSG00000213752		8546	3468	rs58667-A	rs58667	0	58667	intergenic_variant	1	0.38	4e-07	6.39794000867204	(ppFEV1)	0.18	[NR] unit increase	Illumina [369771]	N
2013-06-27	23541324	Li X	2013-03-27	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/23541324	Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.	Pulmonary function in asthmatics	1,544 European ancestry individuals		10q26.11	10	117467831	EMX2	AC005871.2			ENSG00000258114	NA	NA	rs4752066-T	rs4752066	0	4752066	intron_variant	0	0.10	6e-07	6.22184874961636	(ppFEV1)	0.3	[NR] unit decrease	Illumina [369771]	N
2013-06-27	23541324	Li X	2013-03-27	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/23541324	Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.	Pulmonary function in asthmatics	1,544 European ancestry individuals		18p11.32	18	849177	YES1	BOLA2P1 - AP000894.1	ENSG00000266575	ENSG00000264179		16708	7349	rs1291183-T	rs1291183	0	1291183	intergenic_variant	1	0.30	4e-06	5.39794000867204	(ppFEV1)	0.18	[NR] unit decrease	Illumina [369771]	N
2013-06-27	23541324	Li X	2013-03-27	J Allergy Clin Immunol	www.ncbi.nlm.nih.gov/pubmed/23541324	Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients.	Pulmonary function in asthmatics	1,544 European ancestry individuals		19p13.11	19	18021731	IL12RB1	ARRDC2 - AC020904.2	ENSG00000105643	ENSG00000273654		7629	672	rs12984174-T	rs12984174	0	12984174	regulatory_region_variant	1	0.87	9e-06	5.04575749056067	(ppFVC)	0.26	[NR] unit decrease	Illumina [369771]	N
2013-05-01	23364394	Lee JY	2013-01-31	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23364394	A genome-wide association study of a coronary artery disease risk variant.	Coronary heart disease	2,123 Korean ancestry cases, 3,591 Korean ancestry controls	3,052 Japanese ancestry cases, 4,976 Japanese ancestry controls	9p21.3	9	22103814	CDKN2A/2B	CDKN2B-AS1			ENSG00000240498	NA	NA	rs1333042-?	rs1333042	0	1333042	intron_variant	0	NR	1e-09	9		1.3	[1.19-1.41]	Affymetrix [521786]	N
2013-05-01	23364394	Lee JY	2013-01-31	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23364394	A genome-wide association study of a coronary artery disease risk variant.	Coronary heart disease	2,123 Korean ancestry cases, 3,591 Korean ancestry controls	3,052 Japanese ancestry cases, 4,976 Japanese ancestry controls	12q24.12	12	111730205	RPL6-PTPN11, ACAD10, ALDH2, C12orf51	ACAD10			ENSG00000111271	NA	NA	rs11066015-A	rs11066015	0	11066015	intron_variant	0	NR	5e-11	10.301029995664		1.41	[1.27-1.56]	Affymetrix [521786]	N
2013-05-01	23364394	Lee JY	2013-01-31	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23364394	A genome-wide association study of a coronary artery disease risk variant.	Coronary heart disease	2,123 Korean ancestry cases, 3,591 Korean ancestry controls	3,052 Japanese ancestry cases, 4,976 Japanese ancestry controls	12q24.11	12	111241410	CUX2	CUX2			ENSG00000111249	NA	NA	rs886126-T	rs886126	0	886126	intron_variant	0	0.66	1e-06	6		1.14	[1.08-1.20]	Affymetrix [521786]	N
2013-05-01	23364394	Lee JY	2013-01-31	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23364394	A genome-wide association study of a coronary artery disease risk variant.	Coronary heart disease	2,123 Korean ancestry cases, 3,591 Korean ancestry controls	3,052 Japanese ancestry cases, 4,976 Japanese ancestry controls	12q24.11	12	110912851	MYL2	MYL2			ENSG00000111245	NA	NA	rs3782889-C	rs3782889	0	3782889	intron_variant	0	0.21	4e-14	13.397940008672		1.26	[1.19-1.34]	Affymetrix [521786]	N
2013-05-01	23364394	Lee JY	2013-01-31	J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/23364394	A genome-wide association study of a coronary artery disease risk variant.	Coronary heart disease	2,123 Korean ancestry cases, 3,591 Korean ancestry controls	3,052 Japanese ancestry cases, 4,976 Japanese ancestry controls	13q12.3	13	28409926	FLT1	FLT1			ENSG00000102755	NA	NA	rs9508025-C	rs9508025	0	9508025	intron_variant	0	0.50	6e-07	6.22184874961636		1.14	[1.08-1.20]	Affymetrix [521786]	N
2014-04-25	24143882	Gelernter J	2013-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/24143882	Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.	Opioid sensitivity	1,383 European ancestry cases, 996 European ancestry controls, 683 African American cases, 2,635 African American controls	2,116 European ancestry individuals, 4,496 African American individuals	4p14	4	41054699	APBB2	APBB2			ENSG00000163697	NA	NA	rs114070671-?	rs114070671	0	114070671	intron_variant	0	0.08	1e-07	7	(AA)	NA		Illumina [988306]	N
2014-04-25	24143882	Gelernter J	2013-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/24143882	Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.	Opioid sensitivity	1,383 European ancestry cases, 996 European ancestry controls, 683 African American cases, 2,635 African American controls	2,116 European ancestry individuals, 4,496 African American individuals	11p15.1	11	17774564	KCNC1	KCNC1			ENSG00000129159	NA	NA	rs60349741-?	rs60349741	0	60349741	3_prime_UTR_variant	0	0.06	5e-07	6.30102999566398	(AA)	NA		Illumina [988306]	N
2014-04-25	24143882	Gelernter J	2013-10-19	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/24143882	Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways.	Opioid sensitivity	1,383 European ancestry cases, 996 European ancestry controls, 683 African American cases, 2,635 African American controls	2,116 European ancestry individuals, 4,496 African American individuals	18q23	18	79864479	KCNG2	KCNG2			ENSG00000178342	NA	NA	rs62103177-?	rs62103177	0	62103177	intron_variant	0	0.06	4e-10	9.39794000867204	(AA)	NA		Illumina [988306]	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1q25.2	1	177883445	SEC16B	AL136114.1			ENSG00000227579	NA	NA	rs633715-C	rs633715	0	633715	intron_variant	0	0.2	7e-20	19.1549019599857	(Overweight)	1.08	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	11p14.1	11	27706992	BDNF	BDNF, AC103796.1			ENSG00000176697, ENSG00000255496	NA	NA	rs2030323-C	rs2030323	0	2030323	intron_variant	0	0.79	5e-17	16.301029995664	(Overweight)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p31.1	1	72299433	NEGR1	AL513166.1			ENSG00000286863	NA	NA	rs2568958-A	rs2568958	0	2568958	intron_variant	0	0.61	4e-16	15.397940008672	(Overweight)	1.06	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	6p12.3	6	50830813	TFAP2B	TFAP2B			ENSG00000008196	NA	NA	rs2206277-T	rs2206277	0	2206277	intron_variant	0	0.18	7e-16	15.1549019599857	(Overweight)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	3q27.2	3	186116710	ETV5	DGKG			ENSG00000058866	NA	NA	rs9816226-T	rs9816226	0	9816226	intron_variant	0	0.82	2e-14	13.698970004336	(Overweight)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p23.3	2	24927427	ADCY3, POMC	ADCY3 - DNAJC27	ENSG00000138031	ENSG00000115137		7588	16209	rs10182181-G	rs10182181	0	10182181	intergenic_variant	1	0.46	3e-14	13.5228787452803	(Overweight)	1.05	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p12.3	16	19923751	GPRC5B	GPRC5B - GPR139	ENSG00000167191	ENSG00000180269		37584	107734	rs12446554-G	rs12446554	0	12446554	intergenic_variant	1	0.86	4e-12	11.397940008672	(Overweight)	1.07	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	16p11.2	16	28871920	SH2B1	SH2B1			ENSG00000178188	NA	NA	rs7498665-G	rs7498665	0	7498665	missense_variant	0	0.4	5e-12	11.301029995664	(Overweight)	1.05	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	15q23	15	67750719	MAP2K5	MAP2K5			ENSG00000137764	NA	NA	rs8028313-C	rs8028313	0	8028313	intron_variant	0	0.79	1e-11	11	(Overweight)	1.06	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	3p12.1	3	85835000	CADM2	CADM2			ENSG00000175161	NA	NA	rs13078807-G	rs13078807	0	13078807	intron_variant	0	0.2	3e-11	10.5228787452803	(Overweight)	1.06	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	12q13.12	12	49832684	LOC144233	BCDIN3D-AS1			ENSG00000258057	NA	NA	rs10875976-A	rs10875976	0	10875976	intron_variant	0	0.49	2e-10	9.69897000433602	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	2p16.1	2	58606358	FANCL	LINC01122			ENSG00000233723	NA	NA	rs6731302-A	rs6731302	0	6731302	intron_variant	0	0.44	2e-09	8.69897000433602	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	14q31.1	14	79437033	NRXN3	NRXN3			ENSG00000021645	NA	NA	rs2370983-A	rs2370983	0	2370983	intron_variant	0	0.62	3e-09	8.52287874528034	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	1p31.1	1	74527379	TNNI3K	FPGT-TNNI3K, TNNI3K			ENSG00000259030, ENSG00000116783	NA	NA	rs1514174-C	rs1514174	0	1514174	intron_variant	0	0.44	1e-08	8	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	5q13.3	5	75719417	C5orf37	POC5 - SLC25A5P9	ENSG00000152359	ENSG00000251078		1969	33153	rs2112347-T	rs2112347	0	2112347	intergenic_variant	1	0.63	1e-08	8	(Overweight)	1.04	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Waist-hip ratio	4,774 European ancestry high waist-to-hip ratio individuals, 5,481 European ancestry low waist-to-hip ratio individuals	3,351 European ancestry high waist-to-hip ratio individuals, 3,352 European ancestry low waist-to-hip ratio individuals	6p25.1	6	6742916	LY86	AL031123.1 - AL136361.1	ENSG00000226281	ENSG00000224532		3886	15360	rs1294421-G	rs1294421	0	1294421	regulatory_region_variant	1	0.62	2e-10	9.69897000433602		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Waist-hip ratio	4,774 European ancestry high waist-to-hip ratio individuals, 5,481 European ancestry low waist-to-hip ratio individuals	3,351 European ancestry high waist-to-hip ratio individuals, 3,352 European ancestry low waist-to-hip ratio individuals	6q22.33	6	127188012	RSPO3	AL356534.1, RSPO3			ENSG00000286215, ENSG00000146374	NA	NA	rs7745274-A	rs7745274	0	7745274	intron_variant	0	0.55	9e-10	9.04575749056067		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Waist-hip ratio	4,774 European ancestry high waist-to-hip ratio individuals, 5,481 European ancestry low waist-to-hip ratio individuals	3,351 European ancestry high waist-to-hip ratio individuals, 3,352 European ancestry low waist-to-hip ratio individuals	1q41	1	219519878	LYPLAL1	LYPLAL1-AS1 - AL356364.1	ENSG00000228536	ENSG00000238232		60509	37314	rs2820464-G	rs2820464	0	2820464	intergenic_variant	1	0.66	7e-09	8.15490195998574		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Waist-hip ratio	4,774 European ancestry high waist-to-hip ratio individuals, 5,481 European ancestry low waist-to-hip ratio individuals	3,351 European ancestry high waist-to-hip ratio individuals, 3,352 European ancestry low waist-to-hip ratio individuals	2q24.3	2	164672366	COBLL1	COBLL1			ENSG00000082438	NA	NA	rs13389219-C	rs13389219	0	13389219	intron_variant	0	0.57	3e-08	7.52287874528034		1.13	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	16q12.2	16	53785981	FTO	FTO			ENSG00000140718	NA	NA	rs11075990-G	rs11075990	0	11075990	intron_variant	0	0.4	2e-51	50.698970004336		1.35	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	18q21.32	18	60191596	MC4R	RNU4-17P - AC090771.1	ENSG00000202468	ENSG00000267620		27889	4959	rs8089364-C	rs8089364	0	8089364	intergenic_variant	1	0.27	4e-21	20.397940008672		1.24	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	2p25.3	2	624678	TMEM18	AC093326.1 - TMEM18	ENSG00000233633	ENSG00000151353		46533	39199	rs2903492-A	rs2903492	0	2903492	intergenic_variant	1	0.83	6e-15	14.2218487496164		1.26	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	1p31.1	1	72299433	NEGR1	AL513166.1			ENSG00000286863	NA	NA	rs2568958-A	rs2568958	0	2568958	intron_variant	0	0.6	2e-14	13.698970004336		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	4p12	4	45180510	GNPDA2	AC108467.1 - THAP12P9	ENSG00000248744	ENSG00000248320		128858	142743	rs10938397-G	rs10938397	0	10938397	intergenic_variant	1	0.43	2e-13	12.698970004336		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	18p11.22	18	10766427	PIEZO2	PIEZO2			ENSG00000154864	NA	NA	rs2865126-A	rs2865126	0	2865126	intron_variant	0		8e-06	5.09691001300806		0.2663	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	Xp21.3	X	26351782	intergenic	AC073614.1 - AC079178.2	ENSG00000228464	ENSG00000231388		5540	145154	rs6526555-C	rs6526555	0	6526555	intergenic_variant	1		5e-06	5.30102999566398		0.2804	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	Xq24	X	117735951	intergenic	AC005002.1 - AC006963.1	ENSG00000224314	ENSG00000279587		335870	158681	rs5910235-G	rs5910235	0	5910235	intergenic_variant	1		7e-06	5.15490195998574		0.2785	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	2p23.3	2	26005338	U6, RAB10	UQCRHP2 - TRMT112P6	ENSG00000237629	ENSG00000268412		10257	22870	rs112288323-T	rs112288323	0	112288323	intergenic_variant	1		2e-06	5.69897000433602		0.302	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	2p23.3	2	26444262	OTOF, CCDC164	DRC1			ENSG00000157856	NA	NA	rs3795958-G	rs3795958	0	3795958	missense_variant	0		4e-06	5.39794000867204		0.2965	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	2p22.2	2	37730337	intergenic	CDC42EP3			ENSG00000163171	NA	NA	rs13012266-C	rs13012266	0	13012266	intron_variant	0		7e-06	5.15490195998574		0.2833	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	2p16.3	2	50533365	NRXN1	NRXN1			ENSG00000179915	NA	NA	rs6750634-A	rs6750634	0	6750634	intron_variant	0		4e-06	5.39794000867204		0.2936	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	4q28.3	4	130105333	intergenic	LINC02465 - LINC02479	ENSG00000249618	ENSG00000251326		130004	270896	rs114646238-C	rs114646238	0	114646238	intergenic_variant	1		9e-06	5.04575749056067		0.2801	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	4q34.3	4	180308047	intergenic	AC096747.1 - NDUFB5P1	ENSG00000287775	ENSG00000251025		190884	265417	rs17834666-A	rs17834666	0	17834666	intergenic_variant	1		1e-06	6		0.307	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	5p15.2	5	10159429	intergenic	AC034229.1 - AC034229.6	ENSG00000249807	ENSG00000280449		21064	9354	rs2009501-C	rs2009501	0	2009501	intergenic_variant	1		2e-06	5.69897000433602		0.2964	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	5p15.2	5	10512585	intergenic	LINC02213			ENSG00000249160	NA	NA	rs111426949-T	rs111426949	0	111426949	intron_variant	0		6e-06	5.22184874961636		0.2871	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	6p25.3	6	1524335	BC087858, DD413621	AL512329.1 - AL512329.2	ENSG00000218027	ENSG00000272279		9046	4029	rs2569872-C	rs2569872	0	2569872	TF_binding_site_variant	1		8e-06	5.09691001300806		0.2821	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	6p23	6	14597751	intergenic	AL109914.1			ENSG00000229646	NA	NA	rs9296949-T	rs9296949	0	9296949	intron_variant	0		2e-06	5.69897000433602		0.3021	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	7p14.3	7	32421112	intergenic	PDE1C			ENSG00000154678	NA	NA	rs62458065-T	rs62458065	0	62458065	intron_variant	0		1e-06	6		0.3067	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	8p23.2	8	5516018	intergenic	AC004944.1 - AC084768.1	ENSG00000253510	ENSG00000254007		6892	143661	rs62494762-C	rs62494762	0	62494762	intergenic_variant	1		2e-06	5.69897000433602		0.3065	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	8q21.13	8	80072800	TPD52	AC036214.3, TPD52			ENSG00000276418, ENSG00000076554	NA	NA	rs181166265-C	rs181166265	0	181166265	intron_variant	0		3e-06	5.52287874528034		0.2952	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	1p35.1	1	33517419	CSMD2	CSMD2			ENSG00000121904	NA	NA	rs10798959-T	rs10798959	0	10798959	intron_variant	0		8e-06	5.09691001300806		0.2835	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	2p25.1	2	11115214	C2orf50, AX746649, FLJ33534	AC062028.1			ENSG00000145063	NA	NA	rs12692432-C	rs12692432	0	12692432	intron_variant	0		6e-06	5.22184874961636		0.2855	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	9p13.1	9	38750582	intergenic	FAM240B - AL845311.1	ENSG00000283329	ENSG00000228467		30154	53425	rs184891496-C	rs184891496	0	184891496	intergenic_variant	1		7e-06	5.15490195998574		0.284	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	10p12.33	10	18236241	CACNB2	CACNB2, AL390783.1			ENSG00000165995, ENSG00000235020	NA	NA	rs2482109-G	rs2482109	0	2482109	intron_variant	0		3e-06	5.52287874528034		0.2978	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	11q23.3	11	115528028	intergenic	CADM1 - AP003174.2	ENSG00000182985	ENSG00000256281		23071	4294	rs7483296-T	rs7483296	0	7483296	TF_binding_site_variant	1		5e-07	6.30102999566398		0.3152	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	13q12.3	13	31551178	intergenic	AL161616.1 - RXFP2	ENSG00000277319	ENSG00000133105		67479	188348	rs1902272-C	rs1902272	0	1902272	intergenic_variant	1		1e-06	6		0.3074	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	14q32.11	14	89831931	BX247991, EFCAB11	AL137230.2, EFCAB11			ENSG00000259053, ENSG00000140025	NA	NA	rs8021963-C	rs8021963	0	8021963	intron_variant	0		2e-06	5.69897000433602		0.3002	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	15q23	15	71877125	MYO9A, SENP8, NR2E3, GRAMD2	MYO9A			ENSG00000066933	NA	NA	rs12050794-G	rs12050794	0	12050794	intron_variant	0		2e-06	5.69897000433602		0.2996	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	16p13.3	16	4953073	PPL, SEC14L5	PPL			ENSG00000118898	NA	NA	rs34924084-A	rs34924084	0	34924084	intron_variant	0		2e-06	5.69897000433602		0.297	unit increase	Illumina [5767231] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	20q11.23	20	36124388	EPB41L1	EPB41L1			ENSG00000088367	NA	NA	rs6141600-C	rs6141600	0	6141600	intron_variant	0	0.28	6e-12	11.2218487496164		1.21	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	12p11.22	12	28416781	CCDC91	CCDC91			ENSG00000123106	NA	NA	rs10843164-T	rs10843164	0	10843164	intron_variant	0	0.68	6e-12	11.2218487496164		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2p23.3	2	25150429	POMC	EFR3B			ENSG00000084710	NA	NA	rs13428823-G	rs13428823	0	13428823	intron_variant	0	0.37	6e-12	11.2218487496164		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1q24.3	1	172250855	DNM3	DNM3			ENSG00000197959	NA	NA	rs12075079-G	rs12075079	0	12075079	intron_variant	0	0.21	7e-12	11.1549019599857		1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p21.31	6	35037307	ANKS1A	ANKS1A			ENSG00000064999	NA	NA	rs13210323-A	rs13210323	0	13210323	intron_variant	0	0.73	8e-12	11.0969100130081		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	14q12	14	24361644	NFATC4	U6 - NFATC4	ENSG00000277091	ENSG00000285485		9487	4029	rs1950500-T	rs1950500	0	1950500	regulatory_region_variant	1	0.3	1e-11	11		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p21.1	6	45276678	SUPT3H	SUPT3H			ENSG00000196284	NA	NA	rs10948222-C	rs10948222	0	10948222	intron_variant	0	0.6	5e-11	10.301029995664		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	12q22	12	93586312	SOCS2	SOCS2 - AC012085.1	ENSG00000120833	ENSG00000186076		2825	54510	rs10492321-A	rs10492321	0	10492321	intergenic_variant	1	0.21	7e-11	10.1549019599857		1.26	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	5p13.3	5	32689612	NPR3	NPR3			ENSG00000113389	NA	NA	rs6450922-C	rs6450922	0	6450922	intron_variant	0	0.75	1e-10	10		1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	9q34.11	9	130588697	FUBP3	FUBP3			ENSG00000107164	NA	NA	rs7466269-A	rs7466269	0	7466269	intron_variant	0	0.64	2e-10	9.69897000433602		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2p22.3	2	33135271	LTBP1	LTBP1			ENSG00000049323	NA	NA	rs1545552-G	rs1545552	0	1545552	intron_variant	0	0.72	2e-10	9.69897000433602		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p21.33	6	31605179	AIF1	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		12173	5904	rs2844479-A	rs2844479	0	2844479	intergenic_variant	1	0.66	3e-10	9.52287874528034		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	5q35.1	5	171754233	FBXW11	AC022440.1 - AC011410.1	ENSG00000285914	ENSG00000253110		16714	19419	rs153750-G	rs153750	0	153750	intergenic_variant	1	0.62	3e-10	9.52287874528034		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	7p15.3	7	23443066	IGF2BP3	IGF2BP3			ENSG00000136231	NA	NA	rs6957923-G	rs6957923	0	6957923	intron_variant	0	0.63	5e-10	9.30102999566398		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	15q26.3	15	100218180	ADAMTS17	ADAMTS17			ENSG00000140470	NA	NA	rs4965593-C	rs4965593	0	4965593	intron_variant	0	0.32	7e-10	9.15490195998574		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	13q14.2	13	49989311	TRIM13	DLEU2			ENSG00000231607	NA	NA	rs9596219-T	rs9596219	0	9596219	intron_variant	0	0.25	1e-09	9		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	11p11.2	11	47419962	PSMC3	PSMC3			ENSG00000165916	NA	NA	rs10838708-G	rs10838708	0	10838708	intron_variant	0	0.53	2e-09	8.69897000433602		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	10q22.3	10	79171724	ZMIZ1	ZMIZ1			ENSG00000108175	NA	NA	rs780151-G	rs780151	0	780151	intron_variant	0	0.57	2e-09	8.69897000433602		1.13	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q14.1	6	80136272	BCKDHB	BCKDHB			ENSG00000083123	NA	NA	rs2322633-T	rs2322633	0	2322633	intron_variant	0	0.5	3e-09	8.52287874528034		1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1p34.2	1	41223266	SCMH1	SCMH1			ENSG00000010803	NA	NA	rs11209718-T	rs11209718	0	11209718	intron_variant	0	0.44	3e-09	8.52287874528034		1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2p21	2	44253811	PPM1B	AC013717.1			ENSG00000285542	NA	NA	rs4953076-G	rs4953076	0	4953076	intron_variant	0	0.25	4e-09	8.39794000867204		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	18q21.1	18	49433130	DYM	DYM, AC100778.1			ENSG00000141627, ENSG00000263895	NA	NA	rs9967417-G	rs9967417	0	9967417	intron_variant	0	0.42	5e-09	8.30102999566398		1.13	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	15q24.1	15	73934424	LOXL1	LOXL1			ENSG00000129038	NA	NA	rs4337252-C	rs4337252	0	4337252	intron_variant	0	0.5	7e-09	8.15490195998574		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2p22.2	2	37733470	CDC42EP3	CDC42EP3			ENSG00000163171	NA	NA	rs17511102-T	rs17511102	0	17511102	intron_variant	0	0.09	2e-08	7.69897000433602		1.4	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1p12	1	118321993	SPAG17	RNA5SP56 - PSMC1P12	ENSG00000222209	ENSG00000226126		57504	292340	rs7534091-A	rs7534091	0	7534091	intergenic_variant	1	0.74	2e-16	15.698970004336		1.22	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p24.3	6	7695740	BMP6	AL390026.1 - BMP6	ENSG00000236512	ENSG00000153162		74862	30359	rs1885486-A	rs1885486	0	1885486	intergenic_variant	1	0.48	5e-17	16.301029995664		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q22.32	6	126530014	C6orf173	AL356534.1			ENSG00000286215	NA	NA	rs1490384-T	rs1490384	0	1490384	intron_variant	0	0.49	1e-16	16		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	5p13.3	5	32818967	C5orf23	NPR3 - AC025459.1	ENSG00000113389	ENSG00000251062		27243	69023	rs9292468-T	rs9292468	0	9292468	intergenic_variant	1	0.4	2e-16	15.698970004336		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	9q21.13	9	75927370	PCSK5	PCSK5			ENSG00000099139	NA	NA	rs11144688-G	rs11144688	0	11144688	intron_variant	0	0.89	4e-16	15.397940008672		1.48	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	3q26.31	3	172208583	FNDC3B	FNDC3B			ENSG00000075420	NA	NA	rs4535251-T	rs4535251	0	4535251	intron_variant	0	0.5	4e-16	15.397940008672		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	20q11.22	20	35201339	PROCR	PROCR			ENSG00000101000	NA	NA	rs8114671-C	rs8114671	0	8114671	intron_variant	0	0.56	1e-15	15		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	15q26.1	15	88852395	ACAN	ACAN			ENSG00000157766	NA	NA	rs2280470-A	rs2280470	0	2280470	intron_variant	0	0.33	1e-15	15		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	18q11.2	18	23141009	CABLES1	CABLES1			ENSG00000134508	NA	NA	rs11082304-T	rs11082304	0	11082304	intron_variant	0	0.5	5e-15	14.301029995664		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1p36.13	1	16980180	MFAP2	MFAP2, AL049569.1			ENSG00000117122, ENSG00000226526	NA	NA	rs2284746-G	rs2284746	0	2284746	intron_variant	0	0.52	5e-15	14.301029995664		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	12q15	12	69433878	FRS2	RPS26P45 - LINC02373	ENSG00000241765	ENSG00000257507		10883	15592	rs10748128-T	rs10748128	0	10748128	intergenic_variant	1	0.35	7e-15	14.1549019599857		1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	17q23.3	17	63901188	CSH1	AC127029.1 - CSHL1	ENSG00000259333	ENSG00000204414		309	8409	rs2941551-G	rs2941551	0	2941551	intergenic_variant	1	0.27	3e-14	13.5228787452803		1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	7p15.1	7	28149464	JAZF1	JAZF1			ENSG00000153814	NA	NA	rs1029534-T	rs1029534	0	1029534	intron_variant	0	0.31	8e-14	13.0969100130081		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	17q11.2	17	30837005	ATAD5	ATAD5, AC130324.2			ENSG00000176208, ENSG00000265334	NA	NA	rs3764419-C	rs3764419	0	3764419	intron_variant	0	0.61	9e-14	13.0457574905607		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1q25.3	1	184037985	GLT25D2	COLGALT2 - TSEN15	ENSG00000198756	ENSG00000198860		256	13666	rs3814333-T	rs3814333	0	3814333	regulatory_region_variant	1	0.33	2e-13	12.698970004336		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	3p13	3	72343990	RYBP	AC134508.1 - RYBP	ENSG00000260670	ENSG00000281766		19963	27835	rs9832740-G	rs9832740	0	9832740	intergenic_variant	1	0.49	5e-13	12.301029995664		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q23.1	6	130024690	L3MBTL3	L3MBTL3			ENSG00000198945	NA	NA	rs1415701-G	rs1415701	0	1415701	intron_variant	0	0.73	5e-13	12.301029995664		1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	14q23.1	14	60490561	C14orf39	C14orf39			ENSG00000179008	NA	NA	rs2093210-C	rs2093210	0	2093210	intron_variant	0	0.42	8e-13	12.0969100130081		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p21.31	6	34613859	C6orf106	ILRUN			ENSG00000196821	NA	NA	rs2744971-G	rs2744971	0	2744971	intron_variant	0	0.15	8e-13	12.0969100130081		1.26	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	3q26.31	3	172447937	GHSR	GHSR			ENSG00000121853	NA	NA	rs572169-T	rs572169	0	572169	synonymous_variant	0	0.31	1e-12	12		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	19p13.3	19	2176404	DOT1L	DOT1L			ENSG00000104885	NA	NA	rs11880992-A	rs11880992	0	11880992	intron_variant	0	0.39	2e-12	11.698970004336		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	3p21.1	3	53091569	RFT1	AC096887.1, RFT1			ENSG00000272305, ENSG00000163933	NA	NA	rs2564921-T	rs2564921	0	2564921	3_prime_UTR_variant	0	0.43	2e-12	11.698970004336		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	9q22.32	9	96399230	ZNF367	ZNF367			ENSG00000165244	NA	NA	rs2025151-G	rs2025151	0	2025151	intron_variant	0	0.18	2e-12	11.698970004336		1.22	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p21.33	6	31297713	HLA-C, HLA-B	LINC02571, HLA-B, HLA-B, HLA-B, HLA-B, HLA-B			ENSG00000256166, ENSG00000228964, ENSG00000223532, ENSG00000234745, ENSG00000224608, ENSG00000206450	NA	NA	rs2247056-T	rs2247056	0	2247056	intron_variant	0	0.27	4e-12	11.397940008672		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	5q31.1	5	132350453	FLJ44796	MIR3936HG			ENSG00000233006	NA	NA	rs10058074-A	rs10058074	0	10058074	intron_variant	0	0.45	4e-12	11.397940008672		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q16.3	6	104919741	LIN28B	LIN28B-AS1			ENSG00000203809	NA	NA	rs9391253-T	rs9391253	0	9391253	intron_variant	0	0.32	5e-12	11.301029995664		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	1q25.2	1	177883445	SEC16B	AL136114.1			ENSG00000227579	NA	NA	rs633715-C	rs633715	0	633715	intron_variant	0	0.19	5e-12	11.301029995664		1.21	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	6p12.3	6	50835337	TFAP2B	TFAP2B			ENSG00000008196	NA	NA	rs987237-G	rs987237	0	987237	intron_variant	0	0.18	2e-11	10.698970004336		1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	11p14.1	11	27706992	BDNF	BDNF, AC103796.1			ENSG00000176697, ENSG00000255496	NA	NA	rs2030323-C	rs2030323	0	2030323	intron_variant	0	0.79	6e-10	9.22184874961636		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	12q13.12	12	49853685	LOC144233	BCDIN3D - AC131157.1	ENSG00000186666	ENSG00000257253		10579	7522	rs7138803-A	rs7138803	0	7138803	intergenic_variant	1	0.38	2e-09	8.69897000433602		1.13	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Body mass index	7,962 European ancestry high body mass index individuals, 8,106 European ancestry low body mass index individuals	4,900 European ancestry high body mass index individuals, 4,891 European ancestry low body mass index individuals	3q27.2	3	186106215	ETV5	DGKG, ETV5			ENSG00000058866, ENSG00000244405	NA	NA	rs1516725-C	rs1516725	0	1516725	intron_variant	0	0.86	4e-08	7.39794000867204		1.21	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2q37.1	2	231513520	C2orf52	LINC00471			ENSG00000181798	NA	NA	rs6750795-T	rs6750795	0	6750795	splice_region_variant	0	0.44	2e-08	7.69897000433602		1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	3q25.32	3	158391590	RSRC1, SHOX2	RSRC1			ENSG00000174891	NA	NA	rs2362965-T	rs2362965	0	2362965	intron_variant	0	0.5	2e-09	8.69897000433602		1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	8p21.2	8	26348561	PPP2R2A	PPP2R2A			ENSG00000221914	NA	NA	rs1594829-C	rs1594829	0	1594829	intron_variant	0	0.77	4e-08	7.39794000867204		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	3q23	3	141414608	ZBTB38	ZBTB38			ENSG00000177311	NA	NA	rs1991431-A	rs1991431	0	1991431	intron_variant	0	0.44	4e-47	46.397940008672		1.33	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	20q11.22	20	35436182	GDF5	GDF5			ENSG00000125965	NA	NA	rs224333-A	rs224333	0	224333	intron_variant	0	0.36	8e-37	36.0969100130081		1.31	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	12q14.3	12	65958046	HMGA2	HMGA2			ENSG00000149948	NA	NA	rs1351394-T	rs1351394	0	1351394	3_prime_UTR_variant	0	0.49	7e-32	31.1549019599857		1.26	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	7q21.2	7	92618762	CDK6	CDK6			ENSG00000105810	NA	NA	rs42235-T	rs42235	0	42235	intron_variant	0	0.3	1e-28	28		1.28	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p22.2	6	26200449	HIST1H2BF	HIST1H2BF			ENSG00000277224	NA	NA	rs806794-A	rs806794	0	806794	3_prime_UTR_variant	0	0.7	1e-25	25		1.26	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	13q14.3	13	50532652	DLEU7	DLEU1, DLEU7			ENSG00000176124, ENSG00000186047	NA	NA	rs3118906-G	rs3118906	0	3118906	intron_variant	0	0.72	2e-24	23.698970004336		1.26	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1q21.2	1	149934520	MTMR11	MTMR11			ENSG00000014914	NA	NA	rs11205303-C	rs11205303	0	11205303	missense_variant	0	0.38	4e-23	22.397940008672		1.25	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	7p22.3	7	2720161	AMZ1	AMZ1			ENSG00000174945	NA	NA	rs798554-C	rs798554	0	798554	intron_variant	0	0.68	4e-23	22.397940008672		1.24	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	4p15.31	4	17950585	LCORL	LCORL			ENSG00000178177	NA	NA	rs6845078-C	rs6845078	0	6845078	intron_variant	0	0.85	3e-22	21.5228787452803		1.38	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	4q31.21	4	144647200	HHIP	HHIP-AS1, AC098588.2, HHIP, AC098588.3			ENSG00000248890, ENSG00000285713, ENSG00000164161, ENSG00000285783	NA	NA	rs7689420-C	rs7689420	0	7689420	non_coding_transcript_exon_variant	0	0.84	4e-21	20.397940008672		1.33	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	17q21.2	17	40442920	IGFBP4	RPL23AP75 - IGFBP4	ENSG00000240125	ENSG00000141753		3003	530	rs584438-C	rs584438	0	584438	regulatory_region_variant	1	0.62	5e-12	11.301029995664		1.18	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1p36.22	1	9257545	H6PD	H6PD			ENSG00000049239	NA	NA	rs6662509-T	rs6662509	0	6662509	intron_variant	0	0.15	3e-10	9.52287874528034		1.23	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q24.2	6	142334664	GPR126	ADGRG6			ENSG00000112414	NA	NA	rs7741741-T	rs7741741	0	7741741	intron_variant	0	0.72	1e-20	20		1.24	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	15q25.2	15	83911404	ADAMTSL3	ADAMTSL3			ENSG00000156218	NA	NA	rs11259933-A	rs11259933	0	11259933	intron_variant	0	0.51	1e-19	19		1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	17q23.2	17	61419288	C17orf82	C17orf82 - TBX4	ENSG00000187013	ENSG00000121075		6008	33116	rs2079795-T	rs2079795	0	2079795	regulatory_region_variant	1	0.32	1e-18	18		1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	4q21.21	4	81263080	PRKG2	PRKG2 - RNU5A-2P	ENSG00000138669	ENSG00000207065		47963	71223	rs1878528-G	rs1878528	0	1878528	intergenic_variant	1	0.33	4e-18	17.397940008672		1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	20p12.3	20	6641038	BMP2	CASC20 - LINC01713	ENSG00000229876	ENSG00000228482		112579	90042	rs2145270-C	rs2145270	0	2145270	regulatory_region_variant	1	0.37	5e-18	17.301029995664		1.2	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	22q12.1	22	27039858	AK055980	RNU6-1066P - AL008638.5	ENSG00000200443	ENSG00000279914		3867	339	rs742004-A	rs742004	0	742004	intergenic_variant	1		3e-06	5.52287874528034		0.2973	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	Xp21.3	X	26351782	VENTXP1	AC073614.1 - AC079178.2	ENSG00000228464	ENSG00000231388		5540	145154	rs6526555-C	rs6526555	0	6526555	intergenic_variant	1		4e-06	5.39794000867204		0.3006	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA/MHPG ratio)	up to 398 European ancestry individuals	NA	Xp21.2	X	30101660	intergenic	PIGFP3 - AC005185.1	ENSG00000227592	ENSG00000270794		83779	107763	rs6628506-A	rs6628506	0	6628506	intergenic_variant	1		1e-06	6		0.3338	unit increase	Illumina [5767231] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Obesity	93,015 European ancestry overweight individuals, 32,858 European ancestry  class I obese individuals, 9,889 European ancestry class II obese individuals, 2,896 European ancestry class III obese individuals, up to 65,840 European ancestry controls	65,332 European ancestry overweight individuals, 22,373 European ancestry class I obese individuals, 5,476 European ancestry class II obese individuals, 1,162 European ancestry class III obese individuals, up to 39,294 European ancestry controls	18q21.32	18	60184530	MC4R	RNU4-17P - AC090771.1	ENSG00000202468	ENSG00000267620		20823	12025	rs10871777-G	rs10871777	0	10871777	intergenic_variant	1	0.24	2e-27	26.698970004336	(Overweight)	1.1	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	2q35	2	217449530	DIRC3	DIRC3			ENSG00000231672	NA	NA	rs11689435-T	rs11689435	0	11689435	intron_variant	0		4e-06	5.39794000867204		0.2941	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	3q26.31	3	175385825	MIR4789, NAALADL2	NAALADL2			ENSG00000177694	NA	NA	rs62287976-T	rs62287976	0	62287976	intron_variant	0		1e-06	6		0.3082	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	4p15.33	4	12109925	intergenic	AC108037.1 - LINC02270	ENSG00000248262	ENSG00000251210		190237	113520	rs187075894-C	rs187075894	0	187075894	intergenic_variant	1		8e-07	6.09691001300806		0.3145	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	4q23	4	99523527	C4orf17	C4orf17			ENSG00000138813	NA	NA	rs13126513-C	rs13126513	0	13126513	intron_variant	0		8e-06	5.09691001300806		0.285	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	6q13	6	71016836	intergenic	B3GAT2 - AL096709.1	ENSG00000112309	ENSG00000287939		59776	11746	rs1158058-T	rs1158058	0	1158058	intergenic_variant	1		5e-06	5.30102999566398		0.2918	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	6q13	6	74448550	AF086303	AL357507.1			ENSG00000223786	NA	NA	rs72960926-A	rs72960926	0	72960926	intron_variant	0		2e-06	5.69897000433602		0.3084	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	9q31.1	9	103607662	intergenic	AL390962.1 - RNA5SP291	ENSG00000226566	ENSG00000253031		177770	81811	rs144649413-A	rs144649413	0	144649413	intergenic_variant	1		9e-06	5.04575749056067		0.2842	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	10q25.1	10	106494706	intergenic	LINC02624 - RPL23AP59	ENSG00000229775	ENSG00000215002		305984	55400	rs2039964-A	rs2039964	0	2039964	intergenic_variant	1		7e-06	5.15490195998574		0.2877	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	10q26.11	10	117845427	intergenic	AL513324.1 - RAB11FIP2	ENSG00000263041	ENSG00000107560		14183	159489	rs1925265-G	rs1925265	0	1925265	intergenic_variant	1		5e-06	5.30102999566398		0.2912	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	10q26.2	10	126579071	C10orf90	C10orf90			ENSG00000154493	NA	NA	rs11245052-A	rs11245052	0	11245052	intron_variant	0		2e-06	5.69897000433602		0.3034	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	11p12	11	38257400	intergenic	LRRC6P1 - AC021713.1	ENSG00000254784	ENSG00000255477		44601	241595	rs5004866-T	rs5004866	0	5004866	regulatory_region_variant	1		2e-06	5.69897000433602		0.3029	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	12q24.11	12	109960340	GIT2, TCHP, ANKRD13A	TCHP, GIT2			ENSG00000139437, ENSG00000139436	NA	NA	rs4766646-T	rs4766646	0	4766646	intron_variant	0		4e-07	6.39794000867204		0.3211	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	16p13.2	16	7853607	intergenic	AC005774.1 - AC093515.1	ENSG00000252138	ENSG00000260289		126656	25192	rs12446289-C	rs12446289	0	12446289	intergenic_variant	1		6e-06	5.22184874961636		0.2893	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	16p13.13	16	10536920	EMP2	EMP2			ENSG00000213853	NA	NA	rs6498068-C	rs6498068	0	6498068	intron_variant	0		6e-06	5.22184874961636		0.2897	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	18q21.31	18	57829073	intergenic	ATP8B1 - RSL24D1P11	ENSG00000081923	ENSG00000231544		25758	9403	rs62094879-T	rs62094879	0	62094879	intergenic_variant	1		6e-06	5.22184874961636		0.2917	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	20q13.33	20	60371431	AK309218	MIR646HG			ENSG00000228340	NA	NA	rs55681231-A	rs55681231	0	55681231	intron_variant	0		7e-07	6.15490195998574		0.3144	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (MHPG)	up to 398 European ancestry individuals	NA	Xq25	X	122833506	intergenic	RPL3P12 - U3	ENSG00000232496	ENSG00000202268		294046	6920	rs4559365-A	rs4559365	0	4559365	intergenic_variant	1		9e-06	5.04575749056067		0.2955	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	2q36.3	2	227227319	BC035052, AK056332, COL4A3	AC097662.1, COL4A3			ENSG00000236432, ENSG00000169031	NA	NA	rs35212277-A	rs35212277	0	35212277	intron_variant	0		9e-06	5.04575749056067		0.2664	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	3p12.3	3	77603591	ROBO2	ROBO2			ENSG00000185008	NA	NA	rs73114594-A	rs73114594	0	73114594	intron_variant	0		7e-06	5.15490195998574		0.272	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	4p13	4	43318490	intergenic	AC111198.1 - AC097451.1	ENSG00000248939	ENSG00000250657		83534	22385	rs2006970-C	rs2006970	0	2006970	intergenic_variant	1		9e-06	5.04575749056067		0.2674	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	6p21.1	6	41994933	CCND3	CCND3			ENSG00000112576	NA	NA	rs9357377-A	rs9357377	0	9357377	intron_variant	0		5e-06	5.30102999566398		0.2747	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	9p22.3	9	16000237	intergenic	CCDC171			ENSG00000164989	NA	NA	rs79156074-T	rs79156074	0	79156074	intron_variant	0		2e-06	5.69897000433602		0.2824	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	10q26.2	10	126134582	ADAM12	ADAM12			ENSG00000148848	NA	NA	rs1278329-G	rs1278329	0	1278329	intron_variant	0		8e-06	5.09691001300806		0.2671	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	11q23.3	11	115528028	intergenic	CADM1 - AP003174.2	ENSG00000182985	ENSG00000256281		23071	4294	rs7483296-T	rs7483296	0	7483296	TF_binding_site_variant	1		8e-07	6.09691001300806		0.2927	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (5-HIAA/ MHPG Ratio)	up to 398 European ancestry individuals	NA	14q21.1	14	38214056	SSTR1, CLEC14A	SSTR1 - CLEC14A	ENSG00000139874	ENSG00000176435		989	39944	rs11622412-T	rs11622412	0	11622412	intergenic_variant	1		5e-08	7.30102999566398		0.323	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA-5-HIAA Factor score)	up to 398 European ancestry individuals	NA	22q12.3	22	34975259	intergenic	AL024495.1			ENSG00000286592	NA	NA	rs9619497-A	rs9619497	0	9619497	intron_variant	0		5e-06	5.30102999566398		0.2273	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	2p23.3	2	26027030	U6, RAB10	UQCRHP2 - TRMT112P6	ENSG00000237629	ENSG00000268412		31949	1178	rs68184094-A	rs68184094	0	68184094	intergenic_variant	1	NR	2e-06	5.69897000433602		0.2363	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	2p23.3	2	26444262	OTOF, CCDC164	DRC1			ENSG00000157856	NA	NA	rs3795958-G	rs3795958	0	3795958	missense_variant	0	NR	2e-06	5.69897000433602		0.2394	unit increase	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	3p25.3	3	11583940	VGLL4	VGLL4			ENSG00000144560	NA	NA	rs6802119-C	rs6802119	0	6802119	intron_variant	0	NR	2e-06	5.69897000433602		0.2341	unit decrease	Illumina [5767231] (imputed)	N
2013-04-04	23319000	Luykx JJ	2013-01-15	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23319000	Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.	Metabolite levels (HVA)	up to 398 European ancestry individuals	NA	3p24.1	3	29234155	intergenic	AC098650.1, RBMS3-AS3, RBMS3			ENSG00000283563, ENSG00000235904, ENSG00000144642	NA	NA	rs4680719-A	rs4680719	0	4680719	intron_variant	0	NR	3e-06	5.52287874528034		0.2301	unit increase	Illumina [5767231] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2p16.1	2	55869757	EFEMP1	EFEMP1			ENSG00000115380	NA	NA	rs3791679-A	rs3791679	0	3791679	intron_variant	0	0.77	8e-16	15.0969100130081		1.22	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6p21.31	6	34227089	HMGA1	CYCSP55 - HMGA1	ENSG00000214810	ENSG00000137309		7023	9784	rs1759645-C	rs1759645	0	1759645	TF_binding_site_variant	1	0.16	5e-15	14.301029995664		1.29	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	20q11.22	20	33716847	PXMP4	PXMP4			ENSG00000101417	NA	NA	rs1074683-C	rs1074683	0	1074683	intron_variant	0	0.76	1e-14	14		1.21	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2p23.3	2	24813989	CENPO, ADCY3, POMC	CENPO			ENSG00000138092	NA	NA	rs11895026-A	rs11895026	0	11895026	intron_variant	0	0.24	1e-13	13		1.19	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	11p11.2	11	48069751	PTPRJ	PTPRJ			ENSG00000149177	NA	NA	rs10838798-T	rs10838798	0	10838798	intron_variant	0	0.31	7e-12	11.1549019599857		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	12p13.2	12	11702839	ETV6	ETV6			ENSG00000139083	NA	NA	rs2856321-G	rs2856321	0	2856321	intron_variant	0	0.37	3e-11	10.5228787452803		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q14.1	6	81090645	FAM46A	AL590824.1 - TENT5A	ENSG00000216352	ENSG00000112773		533456	400794	rs310405-A	rs310405	0	310405	intergenic_variant	1	0.52	1e-10	10		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	13q13.1	13	32572915	APRIN	N4BP2L2 - PDS5B	ENSG00000244754	ENSG00000083642		34030	13537	rs718444-T	rs718444	0	718444	intergenic_variant	1	0.37	2e-10	9.69897000433602		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q25.1	6	152037044	ESR1	ESR1			ENSG00000091831	NA	NA	rs2982712-C	rs2982712	0	2982712	intron_variant	0	0.47	4e-10	9.39794000867204		1.17	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	5q31.1	5	135021015	PITX1	CATSPER3 - PITX1	ENSG00000152705	ENSG00000069011		9319	6719	rs526896-T	rs526896	0	526896	intergenic_variant	1	0.72	9e-10	9.04575749056067		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	8q12.1	8	56296687	RDHE2	AC107952.1 - SDR16C5	ENSG00000254216	ENSG00000170786		43315	3323	rs4075154-A	rs4075154	0	4075154	intergenic_variant	1	0.87	3e-09	8.52287874528034		1.29	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	7q36.1	7	150815084	TMEM176A	TMEM176A - AOC1	ENSG00000002933	ENSG00000002726		9966	9543	rs10231759-C	rs10231759	0	10231759	regulatory_region_variant	1	0.28	4e-09	8.39794000867204		1.15	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	6q22.1	6	117550673	DCBLD1	DCBLD1, AL132671.2			ENSG00000164465, ENSG00000282218	NA	NA	rs9285425-G	rs9285425	0	9285425	intron_variant	0	0.5	2e-08	7.69897000433602		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	4q24	4	105213159	KIAA1546	TET2			ENSG00000168769	NA	NA	rs6855629-G	rs6855629	0	6855629	intron_variant	0	0.63	2e-08	7.69897000433602		1.14	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	1q41	1	218821931	LYPLAL1	U3 - NXNP1	ENSG00000202268	ENSG00000226693		280032	59669	rs7552186-C	rs7552186	0	7552186	intergenic_variant	1	0.62	3e-08	7.52287874528034		1.12	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2013-09-12	23563607	Berndt SI	2013-04-07	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Height	8,097 European ancestry tall individuals, 8,099 European ancestry short individuals	4,872 European ancestry tall individuals, 4,831 European ancestry short individuals	2q37.1	2	232123872	DIS3L2	DIS3L2			ENSG00000144535	NA	NA	rs3103267-C	rs3103267	0	3103267	intron_variant	0	0.72	3e-08	7.52287874528034		1.16	[NR]	Affymetrix, Illumina [~ 2800000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	11p11.2	11	48518671	OR4A47	OR4A40P - OR4A43P	ENSG00000254832	ENSG00000255534		5451	7393	rs11039798-A	rs11039798	0	11039798	intergenic_variant	1	0.1345	4e-06	5.39794000867204		0.0883	[0.051-0.126] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	13q34	13	111921290	intergenic	LINC00354 - AL138691.1	ENSG00000226903	ENSG00000200072		20026	130788	rs9577381-A	rs9577381	0	9577381	intergenic_variant	1	0.3263	2e-06	5.69897000433602		0.0714	[0.042-0.101] unit decrease	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	20q13.2	20	54846436	intergenic	DOK5 - RNU4ATAC7P	ENSG00000101134	ENSG00000252089		195267	13252	rs1512060-T	rs1512060	0	1512060	intergenic_variant	1	0.0499	6e-06	5.22184874961636		0.2092	[0.12-0.3] unit decrease	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	1p34.3	1	37627051	C1orf109, RSPO1, SNIP1, EPHA10, GNL2, DNALI1, CDCA8	RSPO1			ENSG00000169218	NA	NA	rs4074961-T	rs4074961	0	4074961	intron_variant	0	0.4361	4e-13	12.397940008672		0.0728	[0.053-0.092] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	1q41	1	219602090	LOC388739, LOC728518, ZC3H11B	AL356364.1 - ZC3H11B	ENSG00000238232	ENSG00000215817		44389	5920	rs994767-A	rs994767	0	994767	intergenic_variant	1	0.4085	1e-11	11		0.0716	[0.051-0.092] unit decrease	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	3p21.1	3	53813035	SELK, IL17RB, CACNA1D, CHDH, ACTR8	CACNA1D, CHDH			ENSG00000157388, ENSG00000016391	NA	NA	rs893363-A	rs893363	0	893363	3_prime_UTR_variant	0	0.6514	8e-06	5.09691001300806		0.0513	[0.029-0.074] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	3q12.1	3	100125449	FILIP1L, MGC4308, LOC648640, DOC1, C3ORF26, TBC1D23, COL8A1	CMSS1			ENSG00000184220	NA	NA	rs9811920-A	rs9811920	0	9811920	intron_variant	0	0.3975	5e-11	10.301029995664		0.0803	[0.056-0.104] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	3q28	3	189395472	TPRG1	TPRG1 - TP63	ENSG00000188001	ENSG00000073282		70168	235917	rs6789327-A	rs6789327	0	6789327	intergenic_variant	1	0.0012	3e-07	6.52287874528034		3.7647	[2.33-5.2] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	4q13.1	4	64408122	SRD5A2L2	TECRL			ENSG00000205678	NA	NA	rs6836944-T	rs6836944	0	6836944	intron_variant	0	0.0072	3e-06	5.52287874528034		0.8601	[0.5-1.22] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	6q22.33	6	129498893	ARHGAP18, LAMA2	LAMA2, AL356124.1			ENSG00000196569, ENSG00000226149	NA	NA	rs12193446-A	rs12193446	0	12193446	intron_variant	0	0.9092	1e-08	8		0.1219	[0.08-0.164] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	8p11.23	8	37823908	GPR124, RAB11FIP1, PROSC, ERLIN2, BRF2	ADGRA2			ENSG00000020181	NA	NA	rs12676965-T	rs12676965	0	12676965	intron_variant	0	0.8224	3e-06	5.52287874528034		0.062	[0.036-0.088] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	8q21.11	8	73555269	STAU2	STAU2			ENSG00000040341	NA	NA	rs4342585-C	rs4342585	0	4342585	intron_variant	0	0.9826	9e-06	5.04575749056067		0.2559	[0.14-0.37] unit decrease	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	9p21.3	9	21035308	PTPLAD2, KIAA1797, IFNB1	HACD4 - IFNNP1	ENSG00000188921	ENSG00000230208		3668	23463	rs7867456-T	rs7867456	0	7867456	intergenic_variant	1	0.1789	9e-06	5.04575749056067		0.1497	[0.084-0.216] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	9q34.11	9	128640942	PKN3, SET, WDR34, ZDHHC12, ZER1, SPTAN1, GLE1	WDR34			ENSG00000119333	NA	NA	rs12380424-T	rs12380424	0	12380424	splice_region_variant	0	0.0282	6e-06	5.22184874961636		0.2822	[0.16-0.4] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	11p11.2	11	45925913	PHF21A, PEX16, MAPK8IP1, LOC143678, SLC35C1, GYLTL1B, CRY2	LARGE2			ENSG00000165905	NA	NA	rs10838532-C	rs10838532	0	10838532	intron_variant	0	0.248	2e-06	5.69897000433602		0.0603	[0.035-0.085] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	12q13.3	12	56421497	GLS2, SPRYD4, TIMELESS, PAN2, STAT2, MIP, IL23A, APOF	TIMELESS			ENSG00000111602	NA	NA	rs2291738-T	rs2291738	0	2291738	splice_region_variant	0	0.554	4e-07	6.39794000867204		0.0518	[0.032-0.072] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	12q14.3	12	65996188	HMGA2	HMGA2 - MIR6074	ENSG00000149948	ENSG00000276878		29893	27432	rs10400419-T	rs10400419	0	10400419	intergenic_variant	1	0.3837	2e-07	6.69897000433602		0.0562	[0.035-0.078] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	15q14	15	34697425	GJD2, ACTC1	LINC02252 - GJD2	ENSG00000261304	ENSG00000159248		26330	53607	rs11073058-T	rs11073058	0	11073058	regulatory_region_variant	1	0.4532	4e-11	10.397940008672		0.0661	[0.047-0.086] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	16q24.2	16	88287830	ZNF469	AC138512.1			ENSG00000261273	NA	NA	rs6540223-T	rs6540223	0	6540223	intron_variant	0	0.6751	7e-08	7.15490195998574		0.0631	[0.04-0.086] unit increase	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	20p12.3	20	6780865	BMP2	BMP2 - AL096799.1	ENSG00000125845	ENSG00000232271		619	288749	rs6054512-T	rs6054512	0	6054512	intergenic_variant	1	0.6391	4e-07	6.39794000867204		0.0589	[0.036-0.082] unit decrease	Illumina [2500000] (imputed)	N
2014-02-25	24144296	Cheng CY	2013-08-08	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/24144296	Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.	Axial length	12,531 European ancestry individuals	8,216 Asian ancestry individuals	20q13.33	20	61683795	CDH4	CDH4			ENSG00000179242	NA	NA	rs16985437-A	rs16985437	0	16985437	intron_variant	0	0.0092	3e-06	5.52287874528034		0.4569	[0.27-0.65] unit increase	Illumina [2500000] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	1q25.2	1	177920345	SEC16B	AL136114.1 - SEC16B	ENSG00000227579	ENSG00000120341		193	3611	rs543874-G	rs543874	0	543874	intergenic_variant	1	0.25	2e-13	12.698970004336	(AA and Sub-Saharan)	0.06	[0.044-0.076] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	2p23.3	2	24894108	ADCY3	ADCY3			ENSG00000138031	NA	NA	rs7586879-T	rs7586879	0	7586879	intron_variant	0	0.34	4e-08	7.39794000867204	(AA and Sub-Saharan)	0.047	[0.029-0.065] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	4p12	4	45182425	GNPDA2	AC108467.1 - THAP12P9	ENSG00000248744	ENSG00000248320		130773	140828	rs348495-G	rs348495	0	348495	intergenic_variant	1	0.34	2e-10	9.69897000433602	(AA and Sub-Saharan)	0.051	[0.035-0.067] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	16q12.2	16	53794154	FTO	FTO			ENSG00000140718	NA	NA	rs17817964-T	rs17817964	0	17817964	intron_variant	0	0.12	1e-10	10	(AA and Sub-Saharan)	0.073	[0.051-0.095] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	5q33.2	5	154163906	GALNT10	MFAP3			ENSG00000037749	NA	NA	rs7708584-A	rs7708584	0	7708584	intron_variant	0	0.42	5e-14	13.301029995664		0.021	[0.012-0.030] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	6q16.1	6	96971722	KLHL32	KLHL32			ENSG00000186231	NA	NA	rs974417-C	rs974417	0	974417	intron_variant	0	0.85	6e-06	5.22184874961636		0.0049	[-0.00784-0.01764] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2013-08-23	23583978	Monda KL	2013-04-14	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23583978	A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.	Body mass index	37,956 African American individuals, 1,188 Nigerian ancestry individuals	27,661 African America/Afro-Caribbean individuals, 4,607 Sub-Saharan African ancestry individuals, 123,706 European ancestry inidividuals	7p15.2	7	25910925	NFE2L3, MIR148A	AC018706.1 - AC010719.1	ENSG00000286725	ENSG00000270933		79016	37732	rs10261878-C	rs10261878	0	10261878	intergenic_variant	1	0.94	1e-10	10		0.032	[0.022-0.042] unit increase	Affymetrix, Illumina [3283202] (imputed)	N
2012-12-04	23017229	Voruganti VS	2012-09-24	Cytokine	www.ncbi.nlm.nih.gov/pubmed/23017229	Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.	Monocyte chemoattractant protein-1 levels	815 Hispanic children	NA									NA	NA	snp2-1167588-?	snp2-1167588	0	NA		1	NR	7e-08	7.15490195998574		NA		Illumina [NR]	N
2012-12-04	23017229	Voruganti VS	2012-09-24	Cytokine	www.ncbi.nlm.nih.gov/pubmed/23017229	Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.	Monocyte chemoattractant protein-1 levels	815 Hispanic children	NA	3p21.31	3	46240900	CCR3	CCR3			ENSG00000183625	NA	NA	rs12636651-?	rs12636651	0	12636651	intron_variant	0	NR	7e-09	8.15490195998574		NA		Illumina [NR]	N
2012-12-04	23017229	Voruganti VS	2012-09-24	Cytokine	www.ncbi.nlm.nih.gov/pubmed/23017229	Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.	Monocyte chemoattractant protein-1 levels	815 Hispanic children	NA	9q34.3	9	136371144	CARD9	CARD9			ENSG00000187796	NA	NA	rs34971035-?	rs34971035	0	34971035	splice_region_variant	0	NR	5e-08	7.30102999566398		NA		Illumina [NR]	N
2012-12-04	23017229	Voruganti VS	2012-09-24	Cytokine	www.ncbi.nlm.nih.gov/pubmed/23017229	Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.	Monocyte chemoattractant protein-1 levels	815 Hispanic children	NA									NA	NA	snp10-4307576-?	snp10-4307576	0	NA		1	NR	5e-08	7.30102999566398		NA		Illumina [NR]	N
2012-12-04	23017229	Voruganti VS	2012-09-24	Cytokine	www.ncbi.nlm.nih.gov/pubmed/23017229	Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.	Monocyte chemoattractant protein-1 levels	815 Hispanic children	NA	1q23.2	1	159205564	DARC	ACKR1, CADM3-AS1			ENSG00000213088, ENSG00000225670	NA	NA	rs12075-A	rs12075	0	12075	missense_variant	0	0.43	1e-21	21		NA		Illumina [NR]	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	2p23.3	2	27525757	GCKR	GCKR - C2orf16	ENSG00000084734	ENSG00000221843		2073	11629	rs1260333-C	rs1260333	0	1260333	intergenic_variant	1	0.55	2e-19	18.698970004336		0.05	[0.04-0.06] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	2p24.1	2	20981153	APOB	LINC02850 - AC115619.1	ENSG00000236436	ENSG00000261012		119492	18160	rs6544366-T	rs6544366	0	6544366	intergenic_variant	1	0.22	2e-07	6.69897000433602		0.04	[0.03-0.05] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	8q24.13	8	125478730	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs2954029-T	rs2954029	0	2954029	intron_variant	0	0.46	2e-11	10.698970004336		0.04	[0.03-0.05] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	19p13.11	19	19678719	CILP2, ZNF101	ZNF101			ENSG00000181896	NA	NA	rs2304130-G	rs2304130	0	2304130	splice_region_variant	0	0.09	4e-08	7.39794000867204		0.07	[0.04-0.10] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	5q11.2	5	56558326	C5orf35	C5orf67			ENSG00000225940	NA	NA	rs6867983-T	rs6867983	0	6867983	intron_variant	0	0.12	3e-06	5.52287874528034		0.02	[0.01-0.03] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	1p31.3	1	62531167	DOCK7, ANGPTL3	DOCK7			ENSG00000116641	NA	NA	rs1168013-G	rs1168013	0	1168013	intron_variant	0	0.65	6e-08	7.22184874961636		0.04	[0.03-0.05] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	8p21.3	8	19970337	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		3078	108777	rs10105606-C	rs10105606	0	10105606	regulatory_region_variant	1	0.68	4e-26	25.397940008672		0.07	[0.06-0.08] increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	4q22.1	4	87109109	AFF1	AFF1			ENSG00000172493	NA	NA	rs442177-A	rs442177	0	442177	intron_variant	0	0.50	3e-10	9.52287874528034		0.02	[0.01-0.03] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	11q12.2	11	61803876	FADS1	FADS1, FADS2			ENSG00000149485, ENSG00000134824	NA	NA	rs174548-G	rs174548	0	174548	5_prime_UTR_variant	0	0.17	5e-14	13.301029995664		0.03	[0.02-0.04] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	7q11.23	7	73442100	TBL2, MLXIPL, BAZ1B, BCL7B	BAZ1B			ENSG00000009954	NA	NA	rs1178979-A	rs1178979	0	1178979	3_prime_UTR_variant	0	0.80	2e-12	11.698970004336		0.05	[0.03-0.07] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Triglycerides	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	11q23.3	11	116714271	ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		55976	33899	rs4938303-T	rs4938303	0	4938303	intergenic_variant	1	0.75	4e-21	20.397940008672		0.07	[0.06-0.08] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	1p13.3	1	109275216	CELSR2	CELSR2			ENSG00000143126	NA	NA	rs660240-A	rs660240	0	660240	3_prime_UTR_variant	0	0.21	1e-26	26		0.04	[0.03-0.05] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	1p32.3	1	55030366	PCSK9	BSND - PCSK9	ENSG00000162399	ENSG00000169174		13194	9182	rs11206510-T	rs11206510	0	11206510	intergenic_variant	1	0.77	1e-10	10		0.03	[0.02-0.04] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	2p24.1	2	21063185	APOB	APOB - AC010872.2	ENSG00000084674	ENSG00000287956		19112	30916	rs515135-A	rs515135	0	515135	intergenic_variant	1	0.19	2e-20	19.698970004336		0.04	[0.03-0.05] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	5q13.3	5	75360714	HMGCR	CERT1, HMGCR			ENSG00000113163, ENSG00000113161	NA	NA	rs12916-T	rs12916	0	12916	3_prime_UTR_variant	0	0.62	1e-11	11		0.02	[0.01-0.03] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	19q13.32	19	44919689	APOC2, APOE, APOC4, APOC1	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-G	rs4420638	0	4420638	regulatory_region_variant	1	0.18	2e-40	39.698970004336		0.06	[0.05-0.07] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	8q24.13	8	125469835	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs2954021-G	rs2954021	0	2954021	intron_variant	0	0.50	1e-07	7		0.02	[0.01-0.03] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	11q23.3	11	116736721	ZNF259, APOA1, APOC3, APOA4, APOA5, BUD13	LINC02702 - BUD13	ENSG00000237937	ENSG00000137656		78426	11449	rs1558861-T	rs1558861	0	1558861	regulatory_region_variant	1	0.94	2e-06	5.69897000433602		0.03	[0.02-0.04] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	19p13.2	19	11127797	LDLR	LDLR			ENSG00000130164	NA	NA	rs2738459-C	rs2738459	0	2738459	intron_variant	0	0.48	7e-06	5.15490195998574		0.02	[0.01-0.03] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	8p23.1	8	9327636	PPP1R3B	AC022784.1			ENSG00000248538	NA	NA	rs2126259-A	rs2126259	0	2126259	intron_variant	0	0.13	7e-12	11.1549019599857		0.02	[0.01-0.03] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	19p13.11	19	19296909	SF4, CILP2	SUGP1			ENSG00000105705	NA	NA	rs10401969-T	rs10401969	0	10401969	intron_variant	0	0.91	1e-11	11		0.05	[0.04-0.06] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	LDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	6p22.3	6	16196963	MYLIP, GMPR	MRPL42P2 - RNU6-1114P	ENSG00000216364	ENSG00000251831		24932	8051	rs2142672-C	rs2142672	0	2142672	intergenic_variant	1	0.74	2e-08	7.69897000433602		0.01	[0.007-0.015] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	15q21.3	15	58434545	LIPC	ALDH1A2, LIPC			ENSG00000128918, ENSG00000166035	NA	NA	rs261334-G	rs261334	0	261334	intron_variant	0	0.20	5e-22	21.301029995664		0.03	[0.02-0.04] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	18q21.1	18	49655298	LIPG	SMUG1P1 - AC090227.3	ENSG00000267444	ENSG00000267674		4138	84525	rs2156552-T	rs2156552	0	2156552	intergenic_variant	1	0.81	2e-12	11.698970004336		0.03	[0.02-0.04] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	1q42.13	1	230169242	GALNT2	GALNT2			ENSG00000143641	NA	NA	rs10489615-G	rs10489615	0	10489615	intron_variant	0	0.60	4e-09	8.39794000867204		0.02	[0.01-0.03] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	11q23.3	11	116778201	ZNF259, APOA1, APOC3, APOA4, APOA5	ZPR1			ENSG00000109917	NA	NA	rs964184-G	rs964184	0	964184	3_prime_UTR_variant	0	0.12	2e-11	10.698970004336		0.03	[0.02-0.04] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	16q13	16	56951227	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		6363	10696	rs9989419-G	rs9989419	0	9989419	regulatory_region_variant	1	0.60	1e-32	32		0.04	[0.03-0.05] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	2p24.1	2	20976028	APOB	LINC02850 - AC115619.1	ENSG00000236436	ENSG00000261012		114367	23285	rs11902417-G	rs11902417	0	11902417	intergenic_variant	1	0.78	4e-07	6.39794000867204		0.02	[0.01-0.03] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	11q12.2	11	61803876	FADS1	FADS1, FADS2			ENSG00000149485, ENSG00000134824	NA	NA	rs174548-G	rs174548	0	174548	5_prime_UTR_variant	0	0.17	1e-12	12		0.01	[0.007-0.015] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	8p21.3	8	19961817	LPL	LPL			ENSG00000175445	NA	NA	rs325-T	rs325	0	325	intron_variant	0	0.89	8e-26	25.0969100130081		0.05	[0.04-0.06] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	9p22.3	9	15296036	TTC39B	TTC39B			ENSG00000155158	NA	NA	rs643531-C	rs643531	0	643531	intron_variant	0	0.07	7e-09	8.15490195998574		0.01	[0.009-0.017] unit decrease	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	9q31.1	9	104885374	ABCA1	ABCA1			ENSG00000165029	NA	NA	rs3890182-G	rs3890182	0	3890182	intron_variant	0	0.88	5e-07	6.30102999566398		0.02	[0.01-0.03] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	12q24.11	12	109403135	UBE3B, MVK, MMAB, MYO1H, KCTD10	MYO1H			ENSG00000174527	NA	NA	rs9943753-G	rs9943753	0	9943753	intron_variant	0	0.63	3e-06	5.52287874528034		0.02	[0.01-0.03] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2010-10-17	20864672	Waterworth DM	2010-09-23	Arterioscler Thromb Vasc Biol	www.ncbi.nlm.nih.gov/pubmed/20864672	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	HDL cholesterol	up to 17,723 European ancestry individuals	up to 37,774 European ancestry individuals, up to 9,665 Indian Asian ancestry individuals	16q22.1	16	67674994	GFOD2, LCAT	GFOD2			ENSG00000141098	NA	NA	rs12449157-G	rs12449157	0	12449157	3_prime_UTR_variant	0	0.17	2e-07	6.69897000433602		0.02	[0.01-0.03] unit increase	Affymetrix, Illumina, Perlegen [2155369] (imputed)	N
2008-09-16	18239089	Kong A	2008-02-02	Science	www.ncbi.nlm.nih.gov/pubmed/18239089	Sequence variants in the RNF212 gene associate with genome-wide recombination rate.	Recombination rate (males)	1,887 male individuals	1,248 male individuals	4p16.3	4	1101493	RNF212, SPON2	RNF212, AC092535.3			ENSG00000178222, ENSG00000251639	NA	NA	rs3796619-T	rs3796619	0	3796619	non_coding_transcript_exon_variant	0	0.33 (men and women combined)	3e-24	23.5228787452803		70.7	[57.1-84.3] cM decrease	Illumina [309241]	N
2008-09-17	18239089	Kong A	2008-02-02	Science	www.ncbi.nlm.nih.gov/pubmed/18239089	Sequence variants in the RNF212 gene associate with genome-wide recombination rate.	Recombination rate (females)	1,702 female individuals	1,663 female individuals	4p16.3	4	1084399	RNF212, SPON2	RNF212			ENSG00000178222	NA	NA	rs1670533-C	rs1670533	0	1670533	intron_variant	0	0.23 (men and women combined)	2e-12	11.698970004336		88.2	[63.7-112.7] cM increase	Illumina [309241]	N
2013-04-27	23358156	Benyamin B	2013-01-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23358156	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.	Intelligence (childhood)	12,441 European ancestry children	5,548 European ancestry children	4q32.1	4	159361566	NR	RAPGEF2 - AC074344.1	ENSG00000109756	ENSG00000248552		1392	13533	rs6536413-A	rs6536413	0	6536413	intergenic_variant	1	0.13	6e-06	5.22184874961636		0.075	[0.042-0.108] unit decrease	Affymetrix, Illumina [138093] (imputed)	N
2013-04-27	23358156	Benyamin B	2013-01-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23358156	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.	Intelligence (childhood)	12,441 European ancestry children	5,548 European ancestry children	20p12.1	20	13715482	NR	ESF1			ENSG00000089048	NA	NA	rs6042314-C	rs6042314	0	6042314	intron_variant	0	0.748	7e-06	5.15490195998574		0.058	[0.033-0.083] unit increase	Affymetrix, Illumina [138093] (imputed)	N
2013-04-27	23358156	Benyamin B	2013-01-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23358156	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.	Intelligence (childhood)	12,441 European ancestry children	5,548 European ancestry children	12p13.32	12	5022387	NR	AC005906.2			ENSG00000256654	NA	NA	rs16932667-T	rs16932667	0	16932667	non_coding_transcript_exon_variant	0	0.66	8e-06	5.09691001300806		0.052	[0.028-0.076] unit increase	Affymetrix, Illumina [138093] (imputed)	N
2013-04-27	23358156	Benyamin B	2013-01-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23358156	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.	Intelligence (childhood)	12,441 European ancestry children	5,548 European ancestry children	1q32.3	1	212218821	NR	AL606468.1 - LINC02608	ENSG00000229983	ENSG00000226251		28562	6457	rs6540731-A	rs6540731	0	6540731	regulatory_region_variant	1	0.415	9e-06	5.04575749056067		0.05	[0.028-0.072] unit decrease	Affymetrix, Illumina [138093] (imputed)	N
2013-04-27	23358156	Benyamin B	2013-01-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23358156	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.	Intelligence (childhood)	12,441 European ancestry children	5,548 European ancestry children	2p21	2	43908175	NR	LRPPRC			ENSG00000138095	NA	NA	rs13387221-A	rs13387221	0	13387221	intron_variant	0	0.187	9e-06	5.04575749056067		0.064	[0.035-0.093] unit increase	Affymetrix, Illumina [138093] (imputed)	N
2013-04-27	23358156	Benyamin B	2013-01-29	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/23358156	Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.	Intelligence (childhood)	12,441 European ancestry children	5,548 European ancestry children	8q23.1	8	106832219	NR	ABRA - AP003789.1	ENSG00000174429	ENSG00000275905		61975	148748	rs2981205-T	rs2981205	0	2981205	regulatory_region_variant	1	0.226	5e-06	5.30102999566398		0.06	[0.035-0.085] unit decrease	Affymetrix, Illumina [138093] (imputed)	N
2010-12-16	21060863	Ikram MK	2010-10-28	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21060863	Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.	Retinal vascular caliber	15,358 European ancestry individuals	6,652 European ancestry individuals	19q13.33	19	48725015	FUT2, IZUMO1, FUT1, CA11, FGF21, FLJ36070, RASIP1	RASIP1			ENSG00000105538	NA	NA	rs2287921-T	rs2287921	0	2287921	non_coding_transcript_exon_variant	0	0.47	2e-25	24.698970004336	(Retinal venular caliber)	2.1	[1.71-2.49] um decrease	Affymetrix, Illumina [2194468] (imputed)	N
2010-12-16	21060863	Ikram MK	2010-10-28	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21060863	Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.	Retinal vascular caliber	15,358 European ancestry individuals	6,652 European ancestry individuals	6q24.2	6	142226962	VTA1, NMBR	VTA1 - AL360007.1	ENSG00000009844	ENSG00000237494		2277	24885	rs225717-C	rs225717	0	225717	intergenic_variant	1	0.23	1e-16	16	(Retinal venular caliber)	1.9	[1.45-2.35] um decrease	Affymetrix, Illumina [2194468] (imputed)	N
2010-12-16	21060863	Ikram MK	2010-10-28	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21060863	Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.	Retinal vascular caliber	15,358 European ancestry individuals	6,652 European ancestry individuals	12q24.12	12	111472415	SH2B3, ATXN2, PTPN11	ATXN2			ENSG00000204842	NA	NA	rs10774625-A	rs10774625	0	10774625	intron_variant	0	0.48	2e-13	12.698970004336	(Retinal venular caliber)	1.5	[1.11-1.89] um increase	Affymetrix, Illumina [2194468] (imputed)	N
2010-12-16	21060863	Ikram MK	2010-10-28	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21060863	Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.	Retinal vascular caliber	15,358 European ancestry individuals	6,652 European ancestry individuals	5q14.3	5	88551768	MEF2C	LINC00461			ENSG00000245526	NA	NA	rs17421627-G	rs17421627	0	17421627	intron_variant	0	0.08	7e-16	15.1549019599857	(Retinal venular caliber)	3	[2.27-3.73] um increase	Affymetrix, Illumina [2194468] (imputed)	N
2010-12-16	21060863	Ikram MK	2010-10-28	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21060863	Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo.	Retinal vascular caliber	15,358 European ancestry individuals	6,652 European ancestry individuals	8p23.1	8	11246602	XKR6, SOX7, GATA4, MTMR9, PINX1	AF131215.7 - LINC00529	ENSG00000270076	ENSG00000236827		42931	1024	rs7824557-G	rs7824557	0	7824557	regulatory_region_variant	1	0.39	4e-07	6.39794000867204	(Retinal venular caliber)	1	[0.61-1.39] um increase	Affymetrix, Illumina [2194468] (imputed)	N
2008-09-15	18262040	Sandhu MS	2008-02-09	Lancet	www.ncbi.nlm.nih.gov/pubmed/18262040	LDL-cholesterol concentrations: a genome-wide association study.	LDL cholesterol	11,685 European ancestry individuals	Up to 4,979 European ancestry individuals	1p13.3	1	109279544	CELSR2, PSRC1	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		3793	12	rs599839-G	rs599839	0	599839	intergenic_variant	1	0.19	1e-33	33		0.16	[0.14-0.18] mmol/L decrease	Affymetrix, Illumina [up to 461986]	N
2008-09-15	18262040	Sandhu MS	2008-02-09	Lancet	www.ncbi.nlm.nih.gov/pubmed/18262040	LDL-cholesterol concentrations: a genome-wide association study.	LDL cholesterol	11,685 European ancestry individuals	Up to 4,979 European ancestry individuals	19q13.32	19	44919689	APOC1	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-G	rs4420638	0	4420638	regulatory_region_variant	1	0.18	1e-20	20		0.06	[0.04-0.08] mmol/L increase	Affymetrix, Illumina [up to 461986]	N
2008-09-15	18262040	Sandhu MS	2008-02-09	Lancet	www.ncbi.nlm.nih.gov/pubmed/18262040	LDL-cholesterol concentrations: a genome-wide association study.	LDL cholesterol	11,685 European ancestry individuals	Up to 4,979 European ancestry individuals	2p24.1	2	21065449	APOB	APOB - AC010872.2	ENSG00000084674	ENSG00000287956		21376	28652	rs562338-T	rs562338	0	562338	intergenic_variant	1	0.20	1e-09	9		0.04	[0.02-0.06] mmol/L decrease	Affymetrix, Illumina [up to 461986]	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	6p21.33	6	32082981	TNXB	TNXB, TNXB, TNXB, TNXB, TNXB, TNXB			ENSG00000168477, ENSG00000206258, ENSG00000229353, ENSG00000229341, ENSG00000233323, ENSG00000236221	NA	NA	rs1150754-A	rs1150754	0	1150754	intron_variant	0	0.13	6e-29	28.2218487496164	(anti-dsDNA +)	2.21	[1.93-2.53]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	2q32.2	2	191099907	STAT4	STAT4			ENSG00000138378	NA	NA	rs7574865-T	rs7574865	0	7574865	intron_variant	0	0.23	2e-20	19.698970004336	(anti-dsDNA +)	1.77	[1.57-1.99]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	7q32.1	7	128954129	IRF5	AC025594.2 - TNPO3	ENSG00000275106	ENSG00000064419		813	51	rs10488631-C	rs10488631	0	10488631	intergenic_variant	1	0.11	7e-18	17.1549019599857	(anti-dsDNA +)	1.92	[1.66-2.22]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	1p32.3	1	53163913	SLC1A7	SLC1A7 - AL606760.4	ENSG00000162383	ENSG00000277397		21281	17008	rs6695567-?	rs6695567	0	6695567	intergenic_variant	1	0.57	4e-06	5.39794000867204	(anti-dsDNA +)	1.32	[1.18-1.47]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	3q26.32	3	177377284	intergenic	AC117465.1 - LINC00578	ENSG00000226782	ENSG00000228221		28118	64626	rs12629106-?	rs12629106	0	12629106	TF_binding_site_variant	1	0.81	4e-06	5.39794000867204	(case-only)	1.56	[1.30-1.89]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	2q32.2	2	191099907	STAT4	STAT4			ENSG00000138378	NA	NA	rs7574865-T	rs7574865	0	7574865	intron_variant	0	0.28	8e-06	5.09691001300806	(case-only)	1.41	[1.21-1.63]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	20p13	20	2537919	TMC2	TMC2			ENSG00000149488	NA	NA	rs6049839-T	rs6049839	0	6049839	intron_variant	0	0.40	8e-06	5.09691001300806	(case-only)	1.37	[1.19-1.58]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	8p23.1	8	11486464	BLK	AF131216.5 - BLK	ENSG00000284957	ENSG00000136573		5396	430	rs2736340-T	rs2736340	0	2736340	intergenic_variant	1	0.23	3e-07	6.52287874528034	(anti-dsDNA +)	1.38	[1.23-1.56]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	1q25.3	1	183207295	LAMC2	LAMC2			ENSG00000058085	NA	NA	rs525410-?	rs525410	0	525410	intron_variant	0	0.49	6e-07	6.22184874961636	(anti-dsDNA +)	1.33	[1.19-1.47]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	22q11.21	22	21585386	UBE2L3	UBE2L3			ENSG00000185651	NA	NA	rs5754217-T	rs5754217	0	5754217	intron_variant	0	0.19	2e-06	5.69897000433602	(anti-dsDNA +)	1.38	[1.21-1.57]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	1q31.1	1	189754493	intergenic	RNA5SP73 - LINC01701	ENSG00000252553	ENSG00000232212		88237	20972	rs10737562-?	rs10737562	0	10737562	intergenic_variant	1	0.50	7e-06	5.15490195998574	(anti-dsDNA +)	1.3	[1.16-1.45]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	7q32.1	7	128977412	IRF5	TNPO3			ENSG00000064419	NA	NA	rs12531711-G	rs12531711	0	12531711	intron_variant	0	0.11	6e-09	8.22184874961636	(anti-dsDNA -)	1.58	[1.36-1.83]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	2q31.3	2	180649002	intergenic	AC009478.1			ENSG00000225258	NA	NA	rs918959-?	rs918959	0	918959	intron_variant	0	0.91	2e-06	5.69897000433602	(anti-dsDNA -)	1.72	[1.39-2.17]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	11q11	11	55368743	OR4A15	OR4A15			ENSG00000181958	NA	NA	rs7927370-?	rs7927370	0	7927370	missense_variant	0	0.94	7e-06	5.15490195998574	(anti-dsDNA -)	1.92	[1.45-2.56]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	6p21.32	6	32638107	HLA-DR3	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs2187668-A	rs2187668	0	2187668	intron_variant	0	0.12	6e-28	27.2218487496164	(anti-dsDNA +)	2.23	[1.94-2.57]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	16p11.2	16	31301932	ITGAM	ITGAM			ENSG00000169896	NA	NA	rs9888739-T	rs9888739	0	9888739	intron_variant	0	0.13	1e-15	15	(anti-dsDNA +)	1.8	[1.56-2.07]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	4q25	4	108801970	COL25A1	RCC2P8 - COL25A1	ENSG00000250185	ENSG00000188517		12191	6755	rs4956211-A	rs4956211	0	4956211	intergenic_variant	1	0.35	1e-06	6	(anti-dsDNA +)	1.33	[1.19-1.48]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	5q33.3	5	160452971	PTTG1	MIR3142HG			ENSG00000253522	NA	NA	rs2431697-?	rs2431697	0	2431697	intron_variant	0	0.56	2e-06	5.69897000433602	(anti-dsDNA +)	1.32	[1.18-1.47]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	11p15.5	11	589564	KIAA1542	PHRF1, PHRF1			ENSG00000070047, ENSG00000274780	NA	NA	rs4963128-?	rs4963128	0	4963128	intron_variant	0	0.66	4e-06	5.39794000867204	(anti-dsDNA +)	1.33	[1.18-1.49]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	6p21.32	6	32757416	HLA-DQA2	HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2			ENSG00000232629, ENSG00000230675, ENSG00000224305, ENSG00000228813, ENSG00000196610, ENSG00000229493, ENSG00000228254, ENSG00000226165	NA	NA	rs2301271-T	rs2301271	0	2301271	intron_variant	0	0.40	2e-12	11.698970004336	(anti-dsDNA -)	1.47	[1.32-1.63]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	12q21.2	12	76615280	RPL7AP59	AC107032.2			ENSG00000257526	NA	NA	rs2669010-A	rs2669010	0	2669010	intron_variant	0	0.40	5e-06	5.30102999566398	(anti-dsDNA -)	1.28	[1.16-1.42]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	6p21.32	6	32255481	NOTCH4, C6orf10	TSBP1-AS1			ENSG00000225914	NA	NA	rs3130320-T	rs3130320	0	3130320	intron_variant	0	0.39	3e-06	5.52287874528034	(case-only)	1.39	[1.21-1.60]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	3q26.31	3	175243598	NAALADL2	NAALADL2-AS2, NAALADL2			ENSG00000226779, ENSG00000177694	NA	NA	rs1463525-?	rs1463525	0	1463525	intron_variant	0	0.43	8e-06	5.09691001300806	(case-only)	1.37	[1.19-1.59]	Illumina [421318] (imputed)	N
2011-04-07	21408207	Chung SA	2011-03-03	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21408207	Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.	Systemic lupus erythematosus	811 anti-dsDNA positive European ancestry cases, 906 anti-dsDNA negative European ancestry cases, 4,813 European ancestry controls	NA	6p21.32	6	32696681	HLA-DQA2, HLA-DQA1	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		28298	9443	rs2647012-A	rs2647012	0	2647012	intergenic_variant	1	0.44	8e-06	5.09691001300806	(case-only)	1.38	[1.20-1.59]	Illumina [421318] (imputed)	N
2011-04-06	21390209	Hu X	2011-02-24	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21390209	Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.	Alzheimer's disease (late onset)	1,831 European ancestry cases, 1,764 European ancestry controls	751 cases, 751 controls	2q14.3	2	127130409	BIN1	BIN1 - AC110926.2	ENSG00000136717	ENSG00000286400		23121	11567	rs12989701-?	rs12989701	0	12989701	regulatory_region_variant	1	NR	3e-10	9.52287874528034		1.23	[NR]	Affymetrix, Illumina [NR] (imputed)	N
2011-04-06	21390209	Hu X	2011-02-24	PLoS One	www.ncbi.nlm.nih.gov/pubmed/21390209	Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.	Alzheimer's disease (late onset)	1,831 European ancestry cases, 1,764 European ancestry controls	751 cases, 751 controls	2q14.3	2	127137039	BIN1	BIN1 - AC110926.2	ENSG00000136717	ENSG00000286400		29751	4937	rs744373-?	rs744373	0	744373	regulatory_region_variant	1	NR	1e-10	10		1.19	[NR]	Affymetrix, Illumina [NR] (imputed)	N
2011-04-06	21355061	Boger CA	2011-02-25	J Am Soc Nephrol	www.ncbi.nlm.nih.gov/pubmed/21355061	CUBN is a gene locus for albuminuria.	Urinary albumin excretion	31,580 European ancestry individuals	31,277 European ancestry individuals	10p13	10	16877053	RSU1, CUBN	CUBN			ENSG00000107611	NA	NA	rs1801239-T	rs1801239	0	1801239	missense_variant	0	0.90	1e-11	11	(UACR)	0.0835	[NR] unit decrease CKDGen	Affymetrix, Illumina [~ 2500000] (imputed)	N
2008-09-12	18245381	Uda M	2008-02-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/18245381	Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.	Fetal hemoglobin levels	4,305 European ancestry individuals	521 European ancestry individuals	11p15.4	11	5285279	HBB	HBE1, AC104389.5, HBG2			ENSG00000213931, ENSG00000239920, ENSG00000196565	NA	NA	rs4910742-A	rs4910742	0	4910742	intron_variant	0	0.93	2e-21	20.698970004336		0.58	[NR] unit decrease	Affymetrix [362129]	N
2008-09-12	18245381	Uda M	2008-02-05	Proc Natl Acad Sci U S A	www.ncbi.nlm.nih.gov/pubmed/18245381	Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.	Fetal hemoglobin levels	4,305 European ancestry individuals	521 European ancestry individuals	2p16.1	2	60493111	BCL11A	BCL11A			ENSG00000119866	NA	NA	rs11886868-T	rs11886868	0	11886868	intron_variant	0	0.80	7e-35	34.1549019599857		0.48	[NR] unit decrease	Affymetrix [362129]	N
2008-06-16	18179892	Wallace C	2008-01-10	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18179892	Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.	LDL cholesterol	1,955 European ancestry hypertensive individuals	2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins	1p13.3	1	109279544	PSRC1, CELSR2	CELSR2 - PSRC1	ENSG00000143126	ENSG00000134222		3793	12	rs599839-G	rs599839	0	599839	intergenic_variant	1	0.24	1e-07	7		0.95	[0.93-0.97] mMol/l increase	Affymetrix [400496]	N
2008-06-16	18179892	Wallace C	2008-01-10	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18179892	Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.	LDL cholesterol	1,955 European ancestry hypertensive individuals	2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins	2p23.3	2	27518370	GCKR	GCKR			ENSG00000084734	NA	NA	rs780094-T	rs780094	0	780094	intron_variant	0	0.39	5e-07	6.30102999566398		NA		Affymetrix [400496]	N
2008-06-16	18179892	Wallace C	2008-01-10	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18179892	Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.	LDL cholesterol	1,955 European ancestry hypertensive individuals	2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins	11q23.3	11	116781707	APOA1, APOC3, APOA5	ZPR1			ENSG00000109917	NA	NA	rs6589566-G	rs6589566	0	6589566	intron_variant	0	0.06	3e-11	10.5228787452803		NA		Affymetrix [400496]	N
2008-06-16	18179892	Wallace C	2008-01-10	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/18179892	Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.	Urate levels	1,955 European ancestry hypertensive individuals	2,033 European ancestry individuals from 519 families, 1,461 European ancestry twins	4p16.1	4	9964756	WDR1, SLC2A9	SLC2A9			ENSG00000109667	NA	NA	rs7442295-A	rs7442295	0	7442295	intron_variant	0	0.79	2e-15	14.698970004336		0.02	[0.02-0.03] mMol/L increase	Affymetrix [400496]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q21.32	13	65637888	NR	STARP1 - HNRNPA3P5	ENSG00000214266	ENSG00000236565		326935	150044	rs11619878-G	rs11619878	0	11619878	intergenic_variant	1	0.510985562333036	1e-07	7	(IGP15)	0.1632	[0.1-0.22] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699014551202137	2e-45	44.698970004336	(IGP15)	0.4981	[0.43-0.57] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	80086944	NR	CCDC40			ENSG00000141519	NA	NA	rs1467979-C	rs1467979	0	1467979	non_coding_transcript_exon_variant	0	0.82313228539626	2e-06	5.69897000433602	(IGP15)	0.1923	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q23	15	68426648	NR	ITGA11			ENSG00000137809	NA	NA	rs16952065-C	rs16952065	0	16952065	intron_variant	0	0.93746857524488	6e-06	5.22184874961636	(IGP15)	0.4117	[0.23-0.59] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q11.2	2	99259781	NR	AC079447.1			ENSG00000241962	NA	NA	rs2200578-C	rs2200578	0	2200578	intron_variant	0	0.788386317008014	4e-07	6.39794000867204	(IGP15)	0.1902	[0.12-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q23.2	6	131034724	NR	EPB41L2			ENSG00000079819	NA	NA	rs6908917-C	rs6908917	0	6908917	intron_variant	0	0.751956642030276	2e-06	5.69897000433602	(IGP15)	0.1674	[0.098-0.236] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q13.12	20	45145096	NR	AL049767.1 - PI3	ENSG00000283142	ENSG00000124102		6120	29806	rs7361168-C	rs7361168	0	7361168	intergenic_variant	1	0.758153525448028	3e-06	5.52287874528034	(IGP15)	0.3571	[0.21-0.51] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176763000890472	5e-19	18.301029995664	(IGP15)	0.3911	[0.31-0.48] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q21.23	4	85208463	NR	RN7SKP48 - AC097488.1	ENSG00000201901	ENSG00000248725		107640	37694	rs7691216-G	rs7691216	0	7691216	intergenic_variant	1	0.155663414959929	7e-06	5.15490195998574	(IGP15)	0.1881	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q24.31	12	123832329	NR	DNAH10			ENSG00000197653	NA	NA	rs7978454-G	rs7978454	0	7978454	intron_variant	0	0.409630410507569	7e-06	5.15490195998574	(IGP15)	0.1473	[0.083-0.212] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	95965759	NR	AC008592.2, AC104123.1			ENSG00000250955, ENSG00000251314	NA	NA	rs918629-G	rs918629	0	918629	intron_variant	0	0.745524385574354	1e-06	6	(IGP15)	0.1737	[0.1-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	32870070	NR	AL157884.3 - APTX	ENSG00000236796	ENSG00000137074		475	16531	rs10971170-G	rs10971170	0	10971170	intergenic_variant	1	0.969529949122017	9e-06	5.04575749056067	(IGP16)	0.4143	[0.23-0.6] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q43	1	242368352	NR	PLD5			ENSG00000180287	NA	NA	rs1439523-C	rs1439523	0	1439523	intron_variant	0	0.983777045475011	4e-06	5.39794000867204	(IGP16)	0.6089	[0.35-0.87] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.873857556055831	6e-06	5.22184874961636	(IGP16)	0.2057	[0.12-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p22.3	3	32223499	NR	RPSAP11 - AC097639.1	ENSG00000237433	ENSG00000261572		31872	13189	rs4376071-C	rs4376071	0	4376071	intergenic_variant	1	0.313983692931112	8e-06	5.09691001300806	(IGP16)	0.1605	[0.09-0.231] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q43	1	237435116	NR	RYR2			ENSG00000198626	NA	NA	rs7529251-C	rs7529251	0	7529251	intron_variant	0	0.907539242683476	3e-07	6.52287874528034	(IGP16)	0.2765	[0.17-0.38] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q22.3	11	107476551	NR	CWF19L2 - ALKBH8	ENSG00000152404	ENSG00000137760		18707	26175	rs11212260-C	rs11212260	0	11212260	intergenic_variant	1	0.0281428517133956	5e-06	5.30102999566398	(IGP17)	0.455	[0.26-0.65] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698919993324432	1e-08	8	(IGP17)	0.1999	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33124874	B4GALT1	B4GALT1			ENSG00000086062	NA	NA	rs12342831-C	rs12342831	0	12342831	intron_variant	0	0.262623398308856	3e-11	10.5228787452803	(IGP17)	0.2366	[0.17-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q32.1	2	185319303	NR	ZNF804A - AC009315.1	ENSG00000170396	ENSG00000286797		379811	105760	rs1364477-G	rs1364477	0	1364477	intergenic_variant	1	0.178595763239875	6e-06	5.22184874961636	(IGP17)	0.1816	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q21.1	5	100966102	NR	ST8SIA4 - RN7SL802P	ENSG00000113532	ENSG00000277506		62820	615728	rs17161553-C	rs17161553	0	17161553	intergenic_variant	1	0.00759162019720625	6e-06	5.22184874961636	(IGP17)	1.5958	[0.9-2.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q24.21	12	115774058	NR	AC009387.1			ENSG00000257781	NA	NA	rs17719439-G	rs17719439	0	17719439	intron_variant	0	0.96234668518024	1e-06	6	(IGP17)	0.4037	[0.24-0.57] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p24.1	9	7518656	NR	RPL4P5 - PPIAP33	ENSG00000263127	ENSG00000178654		40336	79167	rs2381628-C	rs2381628	0	2381628	intergenic_variant	1	0.816537394303516	6e-06	5.22184874961636	(IGP17)	0.1783	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p14.3	7	34657448	NR	NPSR1-AS1			ENSG00000197085	NA	NA	rs2530544-G	rs2530544	0	2530544	intron_variant	0	0.768357767245216	8e-07	6.09691001300806	(IGP17)	0.1982	[0.12-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5p14.3	5	18483542	NR	SNORD81 - RN7SL58P	ENSG00000199934	ENSG00000241552		247346	63770	rs4866334-C	rs4866334	0	4866334	regulatory_region_variant	1	0.0883955067200712	4e-06	5.39794000867204	(IGP17)	0.2533	[0.15-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p13.3	9	36099402	RECK	RECK			ENSG00000122707	NA	NA	rs4878639-C	rs4878639	0	4878639	intron_variant	0	0.263725273253227	4e-08	7.39794000867204	(IGP17)	0.1959	[0.13-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q22.3	5	115803051	NR	RNU2-49P - CDO1	ENSG00000222598	ENSG00000129596		28549	1682	rs13174348-G	rs13174348	0	13174348	intergenic_variant	1	0.784686077436582	3e-06	5.52287874528034	(IGP54)	0.1823	[0.11-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187014891	NR	ST6GAL1			ENSG00000073849	NA	NA	rs17776120-C	rs17776120	0	17776120	intron_variant	0	0.636448318202047	2e-06	5.69897000433602	(IGP54)	0.1654	[0.097-0.234] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q34.3	9	134924613	NR	FCN1 - AL353611.1	ENSG00000085265	ENSG00000236403		6701	11911	rs2094962-C	rs2094962	0	2094962	intergenic_variant	1	0.901323053404539	5e-06	5.30102999566398	(IGP54)	0.2366	[0.14-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	2e-07	6.69897000433602	(IGP54)	0.2177	[0.14-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q22.1	8	93210716	NR	C8orf87 - LINC00535	ENSG00000279847	ENSG00000246662		43866	2586	rs278541-C	rs278541	0	278541	intergenic_variant	1	0.97906300623053	4e-08	7.39794000867204	(IGP54)	0.8053	[0.52-1.09] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.122643248331108	7e-06	5.15490195998574	(IGP54)	0.2166	[0.12-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q21.1	18	48701073	NR	CTIF			ENSG00000134030	NA	NA	rs16949825-C	rs16949825	0	16949825	intron_variant	0	0.902274750778816	7e-06	5.15490195998574	(IGP55)	0.2457	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836731980863373	1e-10	10	(IGP55)	0.2864	[0.2-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q12	17	39176710	NR	AC004408.1, CACNB1			ENSG00000266101, ENSG00000067191	NA	NA	rs626657-C	rs626657	0	626657	intron_variant	0	0.861032878949711	2e-06	5.69897000433602	(IGP55)	0.2321	[0.14-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p22	8	14256307	NR	SGCZ			ENSG00000185053	NA	NA	rs9886428-G	rs9886428	0	9886428	intron_variant	0	0.455051607476636	2e-06	5.69897000433602	(IGP55)	0.1472	[0.087-0.207] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p23.3	2	27364857	NR	AC074117.1, EIF2B4			ENSG00000234072, ENSG00000115211	NA	NA	rs1058065-G	rs1058065	0	1058065	synonymous_variant	0	0.97552739311682	4e-06	5.39794000867204	(IGP56)	0.54	[0.31-0.77] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p36.33	1	2274142	NR	SKI			ENSG00000157933	NA	NA	rs12045693-C	rs12045693	0	12045693	intron_variant	0	0.573032700580098	3e-06	5.52287874528034	(IGP56)	0.1539	[0.089-0.219] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q13.3	8	70632513	NR	LACTB2-AS1			ENSG00000246366	NA	NA	rs13272623-G	rs13272623	0	13272623	non_coding_transcript_exon_variant	0	0.155110978134761	4e-06	5.39794000867204	(IGP56)	0.2093	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q21.32	9	81907834	NR	AL158154.1 - SPATA31D5P	ENSG00000200969	ENSG00000240632		18849	5603	rs13295552-C	rs13295552	0	13295552	intergenic_variant	1	0.029172681294964	5e-06	5.30102999566398	(IGP56)	0.9104	[0.52-1.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836660240071397	8e-06	5.09691001300806	(IGP56)	0.2001	[0.11-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q25.1	10	109211677	NR	RNU5B-6P - RNU6-839P	ENSG00000252574	ENSG00000200217		26676	27962	rs17783561-T	rs17783561	0	17783561	intergenic_variant	1	0.135585937974119	6e-06	5.22184874961636	(IGP56)	0.2748	[0.16-0.39] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.21	22	19577734	NR	LINC00895 - AC000077.1	ENSG00000281548	ENSG00000230485		10895	53016	rs2106139-G	rs2106139	0	2106139	regulatory_region_variant	1	0.966774019767961	6e-06	5.22184874961636	(IGP56)	0.4353	[0.25-0.62] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q35	7	147918548	NR	CNTNAP2			ENSG00000174469	NA	NA	rs2538958-C	rs2538958	0	2538958	intron_variant	0	0.436017399375279	8e-06	5.09691001300806	(IGP56)	0.1388	[0.078-0.2] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q12	17	39175092	NR	CACNB1, AC004408.1			ENSG00000067191, ENSG00000266101	NA	NA	rs523516-T	rs523516	0	523516	3_prime_UTR_variant	0	0.176237627398483	4e-06	5.39794000867204	(IGP56)	0.1916	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p22.3	1	84403278	NR	DNASE2B			ENSG00000137976	NA	NA	rs604708-C	rs604708	0	604708	intron_variant	0	0.970210567603748	8e-06	5.09691001300806	(IGP56)	0.4114	[0.23-0.59] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33153529	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813957-G	rs10813957	0	10813957	intron_variant	0	0.738414638629283	3e-09	8.52287874528034	(IGP57)	0.2125	[0.14-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q15	12	69187442	NR	CPM - AC127894.1	ENSG00000135678	ENSG00000258140		215872	24666	rs12367448-C	rs12367448	0	12367448	intergenic_variant	1	0.831671480195817	6e-06	5.22184874961636	(IGP57)	0.2468	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q14.3	2	124534260	NR	CNTNAP5			ENSG00000155052	NA	NA	rs13021885-C	rs13021885	0	13021885	intron_variant	0	0.932509117935024	8e-06	5.09691001300806	(IGP57)	0.3904	[0.22-0.56] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836731980863373	1e-10	10	(IGP57)	0.2872	[0.2-0.37] unit increase	Illumina [~ 2500000] (imputed)	N
2014-01-07	21041247	Perlis RH	2010-11-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21041247	Genome-wide association study of suicide attempts in mood disorder patients.	Suicide risk	3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases	2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases	21q22.2	21	39649825	IGSF5, B3GALT5	B3GALT5, AF064860.1			ENSG00000183778, ENSG00000225330	NA	NA	rs10854398-C	rs10854398	0	10854398	intron_variant	0	NR	6e-06	5.22184874961636		1.178		Affymetrix [1922309] (imputed)	N
2014-01-07	21041247	Perlis RH	2010-11-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21041247	Genome-wide association study of suicide attempts in mood disorder patients.	Suicide risk	3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases	2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases	2p21	2	46093955	intergenic	PRKCE			ENSG00000171132	NA	NA	rs12373805-A	rs12373805	0	12373805	intron_variant	0	NR	9e-06	5.04575749056067		1.2169		Affymetrix [1922309] (imputed)	N
2014-01-07	21041247	Perlis RH	2010-11-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21041247	Genome-wide association study of suicide attempts in mood disorder patients.	Suicide risk	3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases	2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases	10q24.1	10	95362484	PDLIM1, SORBS1	SORBS1			ENSG00000095637	NA	NA	rs4918918-T	rs4918918	0	4918918	intron_variant	0	NR	3e-06	5.52287874528034		1.18		Affymetrix [1922309] (imputed)	N
2014-01-07	21041247	Perlis RH	2010-11-01	Am J Psychiatry	www.ncbi.nlm.nih.gov/pubmed/21041247	Genome-wide association study of suicide attempts in mood disorder patients.	Suicide risk	3,117 European ancestry Bipolar disorder cases, 1,273 European ancestry Major depressive disorder cases	2,698 European ancestry Bipolar disorder cases, 1,649 Major depressive disorder cases	10p11.23	10	30201775	PRKCE	JCAD - RNU6-598P	ENSG00000165757	ENSG00000200887		86281	97794	rs2462021-C	rs2462021	0	2462021	intergenic_variant	1	NR	8e-06	5.09691001300806		1.1755		Affymetrix [1922309] (imputed)	N
2011-04-04	21326295	Jin Y	2011-02-17	J Invest Dermatol	www.ncbi.nlm.nih.gov/pubmed/21326295	Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset.	Vitiligo	1,339 European ancestry cases	677 European ancestry cases	6p21.32	6	32377506	BTNL2, C6orf10	TSBP1-AS1			ENSG00000225914	NA	NA	rs7758128-A	rs7758128	0	7758128	intron_variant	0	0.06	8e-11	10.0969100130081		NA		Illumina [520460]	N
2010-12-01	20971583	Ojwang JO	2010-10-22	J Hand Surg Am	www.ncbi.nlm.nih.gov/pubmed/20971583	Genome-wide association scan of Dupuytren's disease.	Dupuytren's disease	37 European ancestry cases, 36 European ancestry controls	NA	1q41	1	221443734	LOC100132626	LINC02817 - AL360013.2	ENSG00000234754	ENSG00000232436		107245	64825	rs12032381-C	rs12032381	0	12032381	intergenic_variant	1	0.083	6e-06	5.22184874961636		6.22	[2.37-16.31]	Illumina [251837]	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	10q26.12	10	121185572	WDR11, FGFR2	LINC01153			ENSG00000227143	NA	NA	rs3943077-A	rs3943077	0	3943077	non_coding_transcript_exon_variant	0	0.567	3e-14	13.5228787452803		0.07	[0.050-0.090] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	12q13.11	12	48539450	OR8S1, LALBA	AC089987.1 - OR5BS1P	ENSG00000197376	ENSG00000198678		9553	20432	rs11168618-T	rs11168618	0	11168618	intergenic_variant	1	0.137	1e-07	7		0.06	[0.040-0.080] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	6q24.2	6	142798695	HIVEP2	HIVEP2			ENSG00000010818	NA	NA	rs12211360-A	rs12211360	0	12211360	intron_variant	0	0.966	6e-06	5.22184874961636		0.16	[0.10-0.22] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	16q23.3	16	82628663	CDH13	CDH13			ENSG00000140945	NA	NA	rs4783244-T	rs4783244	0	4783244	intron_variant	0	0.360	7e-165	164.154901959986		0.33	[0.31-0.35] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	3q27.3	3	186831906	ADIPOQ	AC112907.2 - ADIPOQ	ENSG00000231982	ENSG00000181092		4569	10798	rs10937273-A	rs10937273	0	10937273	regulatory_region_variant	1	0.404	2e-22	21.698970004336		0.12	[0.10-0.14] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	19q13.11	19	33398094	PEPD	PEPD			ENSG00000124299	NA	NA	rs889140-A	rs889140	0	889140	intron_variant	0	0.450	4e-12	11.397940008672		0.08	[0.060-0.100] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	16q23.2	16	81501185	CMIP	CMIP			ENSG00000153815	NA	NA	rs2925979-T	rs2925979	0	2925979	intron_variant	0	0.411	2e-10	9.69897000433602		0.08	[0.060-0.100] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	12q24.31	12	124006982	ZNF664	AC068790.8, ZNF664, RFLNA			ENSG00000274874, ENSG00000179195, ENSG00000178882	NA	NA	rs1187415-C	rs1187415	0	1187415	intron_variant	0	0.920	2e-07	6.69897000433602		0.11	[0.071-0.149] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	12q24.31	12	122903375	GPR109A	VPS37B - ABCB9	ENSG00000139722	ENSG00000150967		7248	17576	rs10847980-T	rs10847980	0	10847980	regulatory_region_variant	1	0.771	7e-06	5.15490195998574		0.06	[0.040-0.080] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2014-04-26	24105470	Wu Y	2013-10-14	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/24105470	A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.	Adiponectin levels	7,827 East Asian ancestry individuals	10,252 East Asian ancestry individuals	3q27.3	3	186783859	ADIPOQ	AC112907.3, EIF4A2			ENSG00000263826, ENSG00000156976	NA	NA	rs266719-T	rs266719	0	266719	non_coding_transcript_exon_variant	0	0.096	7e-07	6.15490195998574	(Conditioned on rs10937273)	0.13	[0.071-0.189] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2008-06-16	17486107	Baum AE	2007-05-08	Mol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/17486107	A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder.	Bipolar disorder	461 European ancestry cases, 563 European ancestry controls	772 European ancestry cases, 876 European ancestry controls	13q14.11	13	42079301	DGKH	DGKH			ENSG00000102780	NA	NA	rs1012053-A	rs1012053	0	1012053	intron_variant	0	0.84	2e-08	7.69897000433602		1.59	[1.35-1.87]	Illumina [555235]	N
2010-12-09	21079520	Sato Y	2010-11-12	J Thorac Oncol	www.ncbi.nlm.nih.gov/pubmed/21079520	Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel.	Non-small cell lung cancer (survival)	105 East Asian ancestry cases	NA	2q37.1	2	232561816	EIF4E2	EIF4E2			ENSG00000135930	NA	NA	rs1656402-?	rs1656402	0	1656402	intron_variant	0	NR	8e-08	7.09691001300806		2.38	[1.49-3.85] (AG)	Illumina [109365]	N
2010-12-09	21079520	Sato Y	2010-11-12	J Thorac Oncol	www.ncbi.nlm.nih.gov/pubmed/21079520	Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel.	Non-small cell lung cancer (survival)	105 East Asian ancestry cases	NA	21q22.2	21	40043117	DSCAM	DSCAM			ENSG00000171587	NA	NA	rs9981861-G	rs9981861	0	9981861	intron_variant	0	NR	4e-06	5.39794000867204		1.33	[0.82-2.15] (AG)	Illumina [109365]	N
2010-12-09	21079520	Sato Y	2010-11-12	J Thorac Oncol	www.ncbi.nlm.nih.gov/pubmed/21079520	Genome-wide association study on overall survival of advanced non-small cell lung cancer patients treated with carboplatin and paclitaxel.	Non-small cell lung cancer (survival)	105 East Asian ancestry cases	NA	21q22.2	21	38801604	ETS2	LINC00114 - ETS2	ENSG00000223806	ENSG00000157557		54144	3579	rs1209950-T	rs1209950	0	1209950	intergenic_variant	1	NR	3e-07	6.52287874528034		4.96	[2.52-9.76] (CT)	Illumina [109365]	N
2015-05-23	21307088	Khor CC	2011-02-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21307088	Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area.	Optic disc area	2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals	9,326 European ancestry individuals	10q21.3	10	68232096	ATOH7	ATOH7			ENSG00000179774	NA	NA	rs7916697-A	rs7916697	0	7916697	5_prime_UTR_variant	0	NR	2e-15	14.698970004336	(Asian)	0.0938	[NR] mm2 decrease	Illumina [551808]	N
2015-05-23	21307088	Khor CC	2011-02-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21307088	Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area.	Optic disc area	2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals	9,326 European ancestry individuals	22q13.1	22	37523260	CARD10	CARD10 - AL022315.1	ENSG00000100065	ENSG00000225867		3718	26766	rs9607469-A	rs9607469	0	9607469	intergenic_variant	1	0.14	3e-12	11.5228787452803		0.051	[0.036-0.066] mm2 increase	Illumina [551808]	N
2015-05-23	21307088	Khor CC	2011-02-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21307088	Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area.	Optic disc area	2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals	9,326 European ancestry individuals	1p22.1	1	91611540	CDC7, TGFBR3	AL714022.1 - HSP90B3P	ENSG00000229067	ENSG00000203914		11219	30976	rs1192415-G	rs1192415	0	1192415	TF_binding_site_variant	1	NR	8e-17	16.0969100130081	(Asian)	0.0959	[NR] mm2 increase	Illumina [551808]	N
2015-05-23	21307088	Khor CC	2011-02-09	Hum Mol Genet	www.ncbi.nlm.nih.gov/pubmed/21307088	Genome-wide association studies in Asians confirm the involvement of ATOH7 and TGFBR3, and further identify CARD10 as a novel locus influencing optic disc area.	Optic disc area	2,132 Indian ancestry individuals, 2,313 Malay ancestry individuals	9,326 European ancestry individuals	22q13.1	22	37522465	CARD10	CARD10 - AL022315.1	ENSG00000100065	ENSG00000225867		2923	27561	rs6000762-C	rs6000762	0	6000762	intergenic_variant	1	0.3	1e-08	8	(Asian)	0.059	[0.039-0.079] mm2 increase	Illumina [551808]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p22.3	1	86585518	NR	CLCA4-AS1			ENSG00000236915	NA	NA	rs1953652-C	rs1953652	0	1953652	intron_variant	0	0.653295152202937	9e-06	5.04575749056067	(IGP57)	0.1426	[0.08-0.206] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.122643248331108	2e-06	5.69897000433602	(IGP57)	0.2271	[0.13-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p14.1	3	65413223	NR	MAGI1			ENSG00000151276	NA	NA	rs7649739-G	rs7649739	0	7649739	intron_variant	0	0.358836830440587	6e-06	5.22184874961636	(IGP57)	0.1501	[0.085-0.215] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p22	8	14256307	NR	SGCZ			ENSG00000185053	NA	NA	rs9886428-G	rs9886428	0	9886428	intron_variant	0	0.455051607476636	2e-06	5.69897000433602	(IGP57)	0.1476	[0.087-0.208] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q42.12	1	225405225	NR	LBR			ENSG00000143815	NA	NA	rs16844846-G	rs16844846	0	16844846	intron_variant	0	0.0583315441465594	6e-06	5.22184874961636	(IGP58)	0.311	[0.18-0.45] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q14.1	11	80600627	NR	RNU6-544P - ARL6IP1P3	ENSG00000200146	ENSG00000255014		72561	52802	rs2140930-G	rs2140930	0	2140930	intergenic_variant	1	0.348471261394102	5e-06	5.30102999566398	(IGP58)	0.1678	[0.095-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31605179	NR	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		12173	5904	rs2844479-C	rs2844479	0	2844479	intergenic_variant	1	0.393054780607685	7e-06	5.15490195998574	(IGP58)	0.1476	[0.083-0.212] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.873514573726542	3e-06	5.52287874528034	(IGP58)	0.2131	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.636915159517426	3e-08	7.52287874528034	(IGP58)	0.1772	[0.11-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q36.1	7	151217985	ABCF2, SMARCD3	ABCF2, ABCF2			ENSG00000285292, ENSG00000033050	NA	NA	rs1122979-G	rs1122979	0	1122979	intron_variant	0	0.874968858612975	7e-06	5.15490195998574	(IGP59)	0.2213	[0.12-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q24.1	6	139818678	NR	FILNC1			ENSG00000231426	NA	NA	rs12664111-G	rs12664111	0	12664111	intron_variant	0	0.0919615409617097	6e-06	5.22184874961636	(IGP68)	0.2425	[0.14-0.35] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q31.2	1	191970658	NR	LINC02770			ENSG00000228215	NA	NA	rs17403780-T	rs17403780	0	17403780	intron_variant	0	0.910564153517364	7e-06	5.15490195998574	(IGP68)	0.3113	[0.18-0.45] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13319976	NR	SEPHS1			ENSG00000086475	NA	NA	rs1747683-G	rs1747683	0	1747683	intron_variant	0	0.414510834817453	1e-07	7	(IGP68)	0.1694	[0.11-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p14	4	37649533	NR	RELL1			ENSG00000181826	NA	NA	rs2292298-G	rs2292298	0	2292298	intron_variant	0	0.360936488423865	4e-06	5.39794000867204	(IGP68)	0.1504	[0.086-0.215] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.639234834372217	6e-07	6.22184874961636	(IGP68)	0.1618	[0.098-0.225] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q35.1	4	182379461	NR	TENM3			ENSG00000218336	NA	NA	rs4862046-G	rs4862046	0	4862046	intron_variant	0	0.907650657658059	9e-06	5.04575749056067	(IGP68)	0.2467	[0.14-0.36] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p36.11	1	24970252	NR	AL445471.2			ENSG00000261025	NA	NA	rs10751776-C	rs10751776	0	10751776	non_coding_transcript_exon_variant	0	0.54112898484173	7e-06	5.15490195998574	(IGP69)	0.1484	[0.084-0.213] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33128023	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813951-G	rs10813951	0	10813951	intron_variant	0	0.262989649130629	7e-08	7.15490195998574	(IGP69)	0.1926	[0.12-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q32	9	112925455	NR	SLC46A2 - ZNF883	ENSG00000119457	ENSG00000285447		34579	71665	rs10817408-C	rs10817408	0	10817408	regulatory_region_variant	1	0.149316170753455	6e-06	5.22184874961636	(IGP69)	0.2277	[0.13-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p21.1	8	28324238	NR	AC021678.2, PNOC			ENSG00000253690, ENSG00000168081	NA	NA	rs11779594-C	rs11779594	0	11779594	intron_variant	0	0.930937853767276	9e-06	5.04575749056067	(IGP69)	0.2652	[0.15-0.38] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	107951753	LAMB1	LAMB1			ENSG00000091136	NA	NA	rs2072209-G	rs2072209	0	2072209	intron_variant	0	0.0582759206419973	1e-08	8	(IGP69)	0.3742	[0.25-0.5] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189823636647347	2e-08	7.69897000433602	(IGP69)	0.2336	[0.15-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q21.3	3	128939649	NR	KIAA1257			ENSG00000114656	NA	NA	rs2933343-G	rs2933343	0	2933343	intron_variant	0	0.759492835488185	8e-06	5.09691001300806	(IGP69)	0.1615	[0.091-0.232] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299323467231387	9e-06	5.04575749056067	(IGP69)	0.151	[0.084-0.218] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30698892	NR	RPL7P4 - MDC1	ENSG00000238255	ENSG00000206481		1357	915	rs9468811-C	rs9468811	0	9468811	intergenic_variant	1	0.937418950958538	3e-06	5.52287874528034	(IGP69)	0.3228	[0.19-0.46] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189580990204809	8e-15	14.0969100130081	(IGP68)	0.324	[0.24-0.41] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.298923976402493	6e-10	9.22184874961636	(IGP68)	0.2094	[0.14-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836804684351315	2e-06	5.69897000433602	(IGP69)	0.2129	[0.12-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p21	2	46323630	NR	EPAS1			ENSG00000116016	NA	NA	rs7582701-C	rs7582701	0	7582701	intron_variant	0	0.0373370440481498	1e-06	6	(IGP69)	0.4547	[0.27-0.64] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p12.3	3	76676752	NR	ROBO2			ENSG00000185008	NA	NA	rs10511052-G	rs10511052	0	10511052	intron_variant	0	0.950688225100133	6e-06	5.22184874961636	(IGP7)	0.3598	[0.2-0.52] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5p13.2	5	36473135	NR	AC114277.1 - RNA5SP181	ENSG00000287634	ENSG00000222178		125978	12208	rs2937550-C	rs2937550	0	2937550	intergenic_variant	1	0.537253260908281	9e-06	5.04575749056067	(IGP72)	0.1807	[0.1-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299146275601069	2e-15	14.698970004336	(IGP72)	0.2695	[0.2-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p21.3	7	11251773	NR	AC004160.1			ENSG00000230333	NA	NA	rs4720952-G	rs4720952	0	4720952	intron_variant	0	0.419614954873646	4e-07	6.39794000867204	(IGP73)	0.1566	[0.096-0.217] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q24.1	15	73457267	NR	REC114			ENSG00000183324	NA	NA	rs11635553-G	rs11635553	0	11635553	intron_variant	0	0.992804206752874	4e-06	5.39794000867204	(IGP74)	1.0812	[0.62-1.54] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836669484361037	2e-06	5.69897000433602	(IGP74)	0.2132	[0.13-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q12.1	5	61729255	NR	C5orf64			ENSG00000178722	NA	NA	rs4699982-T	rs4699982	0	4699982	intron_variant	0	0.158658866845398	9e-06	5.04575749056067	(IGP74)	0.1943	[0.11-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33128023	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813951-G	rs10813951	0	10813951	intron_variant	0	0.262743396083667	3e-06	5.52287874528034	(IGP76)	0.1669	[0.097-0.237] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p12	2	77019205	NR	LRRTM4			ENSG00000176204	NA	NA	rs6547115-G	rs6547115	0	6547115	intron_variant	0	0.391438525144637	8e-06	5.09691001300806	(IGP76)	0.1432	[0.08-0.206] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q35	2	219999933	NR	AC008281.1 - AC009310.1	ENSG00000286199	ENSG00000225911		87099	48889	rs10198756-C	rs10198756	0	10198756	intergenic_variant	1	0.139068532490975	3e-06	5.52287874528034	(IGP77)	0.2053	[0.12-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q34.2	4	175727181	NR	GPM6A			ENSG00000150625	NA	NA	rs9284954-C	rs9284954	0	9284954	intron_variant	0	0.444965493231047	5e-06	5.30102999566398	(IGP77)	0.1418	[0.081-0.203] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q25.3	6	156336708	NR	AL589693.1			ENSG00000287092	NA	NA	rs12213468-G	rs12213468	0	12213468	intron_variant	0	0.655773469069871	7e-06	5.15490195998574	(IGP8)	0.1455	[0.082-0.209] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.1	1	78521617	NR	PTGFR			ENSG00000122420	NA	NA	rs672561-C	rs672561	0	672561	intron_variant	0	0.257740490431687	9e-06	5.04575749056067	(IGP8)	0.1677	[0.094-0.242] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.122643248331108	5e-07	6.30102999566398	(IGP17)	0.2414	[0.15-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39352849	NR	SYNGR1			ENSG00000100321	NA	NA	rs137699-G	rs137699	0	137699	intron_variant	0	0.690710359535507	8e-06	5.09691001300806	(IGP18)	0.1564	[0.088-0.225] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q31.3	14	85216709	NR	AL357172.1			ENSG00000259044	NA	NA	rs1550584-C	rs1550584	0	1550584	intron_variant	0	0.469772138901295	7e-06	5.15490195998574	(IGP18)	0.1382	[0.078-0.198] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p12	11	41203883	NR	LRRC4C			ENSG00000148948	NA	NA	rs2862035-C	rs2862035	0	2862035	intron_variant	0	0.0246322445734703	8e-06	5.09691001300806	(IGP18)	0.4382	[0.25-0.63] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q23.3	16	83737891	NR	AC009063.2, CDH13			ENSG00000260788, ENSG00000140945	NA	NA	rs444881-C	rs444881	0	444881	intron_variant	0	0.585534589548906	4e-06	5.39794000867204	(IGP18)	0.1441	[0.083-0.206] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q13.12	20	46292992	NR	CDH22			ENSG00000149654	NA	NA	rs6065945-C	rs6065945	0	6065945	intron_variant	0	0.470163670388566	5e-06	5.30102999566398	(IGP18)	0.141	[0.081-0.201] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q24.1	10	96672946	NR	PIK3AP1			ENSG00000155629	NA	NA	rs7895244-T	rs7895244	0	7895244	intron_variant	0	0.929057661098705	5e-06	5.30102999566398	(IGP18)	0.2836	[0.16-0.41] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32146738	PRRT1	FKBPL - PRRT1	ENSG00000230907	ENSG00000227122		16450	1621	rs9296009-T	rs9296009	0	9296009	regulatory_region_variant	1	0.196796488164359	4e-06	5.39794000867204	(IGP18)	0.1779	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	51877490	NR	AC022433.1 - RNA5SP182	ENSG00000288035	ENSG00000251873		212442	9198	rs17835853-G	rs17835853	0	17835853	intergenic_variant	1	0.956794057690593	4e-06	5.39794000867204	(IGP30)	0.4778	[0.27-0.68] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.33	14	104880570	NR	CEP170B			ENSG00000099814	NA	NA	rs2841233-C	rs2841233	0	2841233	intron_variant	0	0.642908958091841	7e-06	5.15490195998574	(IGP30)	0.1475	[0.083-0.212] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	19p13.11	19	19165550	NR	MEF2B, BORCS8-MEF2B			ENSG00000213999, ENSG00000064489	NA	NA	rs7249142-G	rs7249142	0	7249142	intron_variant	0	0.619273395452519	9e-06	5.04575749056067	(IGP30)	0.1523	[0.085-0.219] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q23.1	5	116398108	NR	COMMD10			ENSG00000145781	NA	NA	rs7734156-C	rs7734156	0	7734156	intron_variant	0	0.0499571860008917	7e-06	5.15490195998574	(IGP30)	0.3437	[0.19-0.49] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p14.1	7	41997238	NR	GLI3			ENSG00000106571	NA	NA	rs846271-C	rs846271	0	846271	intron_variant	0	0.628956223807401	2e-06	5.69897000433602	(IGP30)	0.1538	[0.09-0.218] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299100489968792	2e-06	5.69897000433602	(IGP30)	0.1606	[0.095-0.227] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.2	6	37564327	NR	MIR4462 - AL353597.3	ENSG00000263926	ENSG00000279942		8905	3389	rs9394438-G	rs9394438	0	9394438	intergenic_variant	1	0.713317013374944	7e-06	5.15490195998574	(IGP30)	0.1671	[0.094-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q31.1	14	81168979	NR	AC007262.2			ENSG00000284959	NA	NA	rs10131728-C	rs10131728	0	10131728	intron_variant	0	0.872444873552983	2e-07	6.69897000433602	(IGP31)	0.2398	[0.15-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q14.1	12	62424701	NR	USP15 - MON2	ENSG00000135655	ENSG00000061987		7270	42116	rs10877839-C	rs10877839	0	10877839	intergenic_variant	1	0.32479838824577	9e-06	5.04575749056067	(IGP31)	0.1459	[0.082-0.21] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q12	12	38859306	NR	CPNE8			ENSG00000139117	NA	NA	rs11169838-C	rs11169838	0	11169838	intron_variant	0	0.680521641139804	2e-06	5.69897000433602	(IGP31)	0.1764	[0.1-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699014551202137	6e-17	16.2218487496164	(IGP31)	0.2934	[0.22-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p23.3	8	616207	NR	ERICH1			ENSG00000104714	NA	NA	rs17666538-C	rs17666538	0	17666538	3_prime_UTR_variant	0	0.073151367141585	7e-06	5.15490195998574	(IGP31)	0.2848	[0.16-0.41] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q21	6	107339442	NR	PDSS2			ENSG00000164494	NA	NA	rs2430457-G	rs2430457	0	2430457	intron_variant	0	0.00697800000000004	5e-06	5.30102999566398	(IGP31)	2.6041	[1.48-3.73] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	95318169	NR	MCTP1 - FAM81B	ENSG00000175471	ENSG00000153347		33594	73197	rs255982-G	rs255982	0	255982	intergenic_variant	1	0.848905209260908	8e-06	5.09691001300806	(IGP31)	0.2077	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33139455	NR	B4GALT1			ENSG00000086062	NA	NA	rs3780486-C	rs3780486	0	3780486	intron_variant	0	0.737357337934105	1e-06	6	(IGP31)	0.1725	[0.1-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.31	3	155549651	NR	PLCH1			ENSG00000114805	NA	NA	rs3851357-G	rs3851357	0	3851357	intron_variant	0	0.805635591718611	9e-06	5.04575749056067	(IGP31)	0.1814	[0.1-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.1	1	79043424	NR	ADGRL4			ENSG00000162618	NA	NA	rs6687262-C	rs6687262	0	6687262	intron_variant	0	0.552969396260018	2e-06	5.69897000433602	(IGP31)	0.1461	[0.085-0.207] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.4	11	5604373	NR	AC104389.5, TRIM6-TRIM34, TRIM6			ENSG00000239920, ENSG00000258588, ENSG00000121236	NA	NA	rs7108470-G	rs7108470	0	7108470	intron_variant	0	0.423505770703473	3e-06	5.52287874528034	(IGP31)	0.1516	[0.088-0.215] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q23.3	2	152580056	NR	FMNL2			ENSG00000157827	NA	NA	rs11675841-C	rs11675841	0	11675841	intron_variant	0	0.607345676902537	5e-06	5.30102999566398	(IGP70)	0.1458	[0.083-0.208] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13319976	NR	SEPHS1			ENSG00000086475	NA	NA	rs1747683-G	rs1747683	0	1747683	intron_variant	0	0.414548764129951	6e-07	6.22184874961636	(IGP70)	0.1581	[0.096-0.22] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	1e-16	16	(IGP70)	0.3451	[0.26-0.43] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.639172889630619	9e-06	5.04575749056067	(IGP70)	0.1435	[0.08-0.207] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16p13.11	16	16162910	NR	ABCC6, ABCC6			ENSG00000091262, ENSG00000275331	NA	NA	rs3213473-G	rs3213473	0	3213473	intron_variant	0	0.851097327102804	7e-06	5.15490195998574	(IGP70)	0.2016	[0.11-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.3	1	68461830	NR	RPE65 - DEPDC1	ENSG00000116745	ENSG00000024526		11876	12322	rs435066-C	rs435066	0	435066	intergenic_variant	1	0.196103507788162	5e-06	5.30102999566398	(IGP70)	0.1801	[0.1-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p13	3	72468889	NR	RYBP - AC104435.2	ENSG00000281766	ENSG00000244345		22268	35917	rs9832314-G	rs9832314	0	9832314	intergenic_variant	1	0.055934898976413	9e-06	5.04575749056067	(IGP66)	0.2992	[0.17-0.43] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q33.1	9	117796733	NR	AL160272.1, AL160272.2			ENSG00000284977, ENSG00000285082	NA	NA	rs10115586-C	rs10115586	0	10115586	intron_variant	0	0.70273622340899	5e-07	6.30102999566398	(IGP7)	0.1676	[0.1-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p36.33	1	1143818	NR	LINC01342			ENSG00000223823	NA	NA	rs11260603-C	rs11260603	0	11260603	non_coding_transcript_exon_variant	0	0.217058243435692	4e-07	6.39794000867204	(IGP7)	0.2608	[0.16-0.36] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q13.3	8	70632513	NR	LACTB2-AS1			ENSG00000246366	NA	NA	rs13272623-G	rs13272623	0	13272623	non_coding_transcript_exon_variant	0	0.154915348909657	2e-06	5.69897000433602	(IGP7)	0.2155	[0.13-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q15	6	89948064	BACH2	BACH2			ENSG00000112182	NA	NA	rs404256-C	rs404256	0	404256	intron_variant	0	0.559129675122385	7e-09	8.15490195998574	(IGP7)	0.2094	[0.14-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q12	20	42365454	NR	PTPRT			ENSG00000196090	NA	NA	rs6030171-C	rs6030171	0	6030171	intron_variant	0	0.359936573653761	3e-06	5.52287874528034	(IGP7)	0.148	[0.086-0.21] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q12.2	16	53039876	NR	AC007906.2			ENSG00000277639	NA	NA	rs10852453-T	rs10852453	0	10852453	intron_variant	0	0.502934347747748	1e-06	6	(IGP20)	0.1462	[0.088-0.205] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.13	8	124709125	NR	MTSS1			ENSG00000170873	NA	NA	rs11781525-G	rs11781525	0	11781525	intron_variant	0	0.97440182935123	6e-06	5.22184874961636	(IGP59)	0.6033	[0.34-0.87] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	95937706	NR	ELL2			ENSG00000118985	NA	NA	rs7700895-T	rs7700895	0	7700895	intron_variant	0	0.783746748105216	1e-06	6	(IGP35)	0.1776	[0.11-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17p12	17	13805544	NR	COX10-AS1			ENSG00000236088	NA	NA	rs7215286-C	rs7215286	0	7215286	intron_variant	0	0.961960845948353	3e-06	5.52287874528034	(IGP65)	0.4016	[0.23-0.57] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.639172889630619	2e-06	5.69897000433602	(IGP66)	0.1529	[0.089-0.216] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698889241071429	2e-06	5.69897000433602	(IGP36)	0.1678	[0.099-0.237] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p12.1	10	25591530	NR	GPR158			ENSG00000151025	NA	NA	rs17558301-C	rs17558301	0	17558301	intron_variant	0	0.961067	7e-06	5.15490195998574	(IGP36)	1.5855	[0.9-2.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p14.2	3	62796793	NR	CADPS			ENSG00000163618	NA	NA	rs304172-G	rs304172	0	304172	intron_variant	0	0.956126387053571	8e-06	5.09691001300806	(IGP36)	0.3337	[0.19-0.48] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.1	11	19030325	NR	MRGPRX9P			ENSG00000255424	NA	NA	rs7111562-C	rs7111562	0	7111562	non_coding_transcript_exon_variant	0	0.139875874553571	2e-06	5.69897000433602	(IGP36)	0.2255	[0.13-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q16.3	6	104215903	NR	NPM1P10 - AL357522.1	ENSG00000214428	ENSG00000287616		189140	271192	rs2744203-C	rs2744203	0	2744203	intergenic_variant	1	0.0959963838018742	7e-06	5.15490195998574	(IGP39)	0.2327	[0.13-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q22.1	6	114748553	NR	AL138830.1 - AL590550.1	ENSG00000226079	ENSG00000287097		203218	74441	rs6928844-C	rs6928844	0	6928844	regulatory_region_variant	1	0.828187721552878	4e-06	5.39794000867204	(IGP39)	0.285	[0.16-0.41] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.4	11	7443141	NR	AC107884.1, SYT9			ENSG00000251364, ENSG00000170743	NA	NA	rs4076555-C	rs4076555	0	4076555	intron_variant	0	0.336591107706174	7e-06	5.15490195998574	(IGP4)	0.1591	[0.09-0.229] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836659126892253	2e-09	8.69897000433602	(IGP3)	0.2658	[0.18-0.35] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.122476576224399	3e-06	5.52287874528034	(IGP3)	0.2229	[0.13-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p22	8	14256307	NR	SGCZ			ENSG00000185053	NA	NA	rs9886428-G	rs9886428	0	9886428	intron_variant	0	0.455031556990205	3e-06	5.52287874528034	(IGP3)	0.1428	[0.083-0.203] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.3	10	63112651	NR	RNU6-543P - AL590502.1	ENSG00000199446	ENSG00000224301		2405	11278	rs10822136-C	rs10822136	0	10822136	regulatory_region_variant	1	0.805344702630406	5e-07	6.30102999566398	(IGP30)	0.2106	[0.13-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698844000445832	3e-06	5.52287874528034	(IGP30)	0.164	[0.095-0.233] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.4	11	5666794	NR	TRIM5, AC104389.5			ENSG00000132256, ENSG00000239920	NA	NA	rs11820502-C	rs11820502	0	11820502	intron_variant	0	0.287788676326349	2e-06	5.69897000433602	(IGP30)	0.1821	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	28181087	NR	LINGO2			ENSG00000174482	NA	NA	rs1319535-C	rs1319535	0	1319535	intron_variant	0	0.34574886090058	4e-06	5.39794000867204	(IGP30)	0.1509	[0.087-0.215] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p22.1	3	39433851	NR	AC099332.1			ENSG00000286781	NA	NA	rs17038828-C	rs17038828	0	17038828	intron_variant	0	0.979741981275078	8e-06	5.09691001300806	(IGP30)	0.56	[0.31-0.81] unit decrease	Illumina [~ 2500000] (imputed)	N
2008-06-16	17434096	Matarin M	2007-05-06	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17434096	A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.	Stroke	249 European ancestry cases, 268 European ancestry controls	NA	18p11.21	18	11987273	IMPA2	IMPA2			ENSG00000141401	NA	NA	rs7506045-?	rs7506045	0	7506045	intron_variant	0	0.10	7e-07	6.15490195998574		5.39	[2.77-10.5]	Illumina [408803]	N
2008-06-16	17434096	Matarin M	2007-05-06	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17434096	A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.	Stroke	249 European ancestry cases, 268 European ancestry controls	NA	13q14.3	13	54006952	intergenic	LINC00558 - LINC00458	ENSG00000261517	ENSG00000234787		66992	108831	rs9536591-?	rs9536591	0	9536591	intergenic_variant	1	0.10	6e-06	5.22184874961636		1.92	[1.41-2.63]	Illumina [408803]	N
2008-06-16	17434096	Matarin M	2007-05-06	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17434096	A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.	Stroke	249 European ancestry cases, 268 European ancestry controls	NA	6q21	6	106539495	AIM1	CRYBG1			ENSG00000112297	NA	NA	rs783396-?	rs783396	0	783396	missense_variant	0	0.90	9e-06	5.04575749056067		2.17	[1.47-3.13]	Illumina [408803]	N
2008-06-16	17434096	Matarin M	2007-05-06	Lancet Neurol	www.ncbi.nlm.nih.gov/pubmed/17434096	A genome-wide genotyping study in patients with ischaemic stroke: initial analysis and data release.	Stroke	249 European ancestry cases, 268 European ancestry controls	NA	7p21.2	7	15703161	intergenic	RPL36AP26 - AC006041.2	ENSG00000235828	ENSG00000286376		1409	33212	rs10486776-?	rs10486776	0	10486776	intergenic_variant	1	0.10	6e-06	5.22184874961636		5.62	[2.66-11.9]	Illumina [408803]	N
2013-09-25	20064070	Herbeck JT	2010-02-15	J Infect Dis	www.ncbi.nlm.nih.gov/pubmed/20064070	Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS.	HIV-1 progression	51 European ancestry rapid progressor male cases, 57 European ancestry moderate progressor male cases, 48 European ancestry long-term progressor male cases	590 European ancestry seroconverter male cases	1q32.3	1	213951784	PROX1	PROX1-AS1			ENSG00000230461	NA	NA	rs17762192-G	rs17762192	0	17762192	intron_variant	0	0.59	2e-06	5.69897000433602		1.45	[NR]	Affymetrix [345926]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32706960	NR	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		5	11045	rs1794265-C	rs1794265	0	1794265	intergenic_variant	1	0.945736455079007	1e-06	6	(IGP19)	0.3272	[0.2-0.46] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p24.2	3	25302124	NR	RARB			ENSG00000077092	NA	NA	rs322668-G	rs322668	0	322668	intron_variant	0	0.285734488487585	4e-06	5.39794000867204	(IGP19)	0.159	[0.092-0.226] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q35.1	5	170034543	NR	DOCK2			ENSG00000134516	NA	NA	rs3763048-C	rs3763048	0	3763048	synonymous_variant	0	0.672342024379233	9e-06	5.04575749056067	(IGP19)	0.1425	[0.08-0.205] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31834688	NR	SNHG32, SNHG32, SNHG32, SNHG32, AL671762.1			ENSG00000226710, ENSG00000234728, ENSG00000204387, ENSG00000229300, ENSG00000285565	NA	NA	rs4711279-C	rs4711279	0	4711279	5_prime_UTR_variant	0	0.823257144469526	3e-07	6.52287874528034	(IGP19)	0.1964	[0.12-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p13.3	2	70836812	NR	CD207 - LINC01143	ENSG00000116031	ENSG00000237751		996	51059	rs4852708-C	rs4852708	0	4852708	intergenic_variant	1	0.875251656884876	9e-06	5.04575749056067	(IGP19)	0.2055	[0.11-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	96092980	NR	MIR583HG, AC104123.1			ENSG00000250551, ENSG00000251314	NA	NA	rs7734985-G	rs7734985	0	7734985	intron_variant	0	0.336041271783296	2e-06	5.69897000433602	(IGP19)	0.1571	[0.093-0.221] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30698892	NR	RPL7P4 - MDC1	ENSG00000238255	ENSG00000206481		1357	915	rs9468811-C	rs9468811	0	9468811	intergenic_variant	1	0.937946818961625	6e-07	6.22184874961636	(IGP19)	0.3471	[0.21-0.48] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32759026	HLA-DQA2, HLA-DQB2	HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2			ENSG00000232629, ENSG00000230675, ENSG00000224305, ENSG00000228813, ENSG00000196610, ENSG00000229493, ENSG00000228254, ENSG00000226165	NA	NA	rs1049110-C	rs1049110	0	1049110	missense_variant	0	0.34601888034188	4e-08	7.39794000867204	(IGP2)	0.1853	[0.12-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q32.3	1	214283666	NR	SMYD2			ENSG00000143499	NA	NA	rs9308433-C	rs9308433	0	9308433	intron_variant	0	0.408224476833108	4e-06	5.39794000867204	(IGP2)	0.1457	[0.084-0.207] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q23.2	5	127386161	NR	MEGF10			ENSG00000145794	NA	NA	rs10519937-C	rs10519937	0	10519937	intron_variant	0	0.831854334233018	9e-06	5.04575749056067	(IGP2)	0.188	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q36.1	7	151217985	ABCF2, SMARCD3	ABCF2, ABCF2			ENSG00000285292, ENSG00000033050	NA	NA	rs1122979-G	rs1122979	0	1122979	intron_variant	0	0.875182808816914	2e-10	9.69897000433602	(IGP2)	0.3134	[0.22-0.41] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p12	8	31176759	NR	AC009563.1			ENSG00000253961	NA	NA	rs11774682-C	rs11774682	0	11774682	non_coding_transcript_exon_variant	0	0.96615368329177	1e-06	6	(IGP2)	0.8276	[0.49-1.16] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.390847885290148	8e-20	19.0969100130081	(IGP2)	0.2915	[0.23-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.2	9	27126417	NR	TEK			ENSG00000120156	NA	NA	rs1334809-G	rs1334809	0	1334809	intron_variant	0	0.884652631578947	8e-06	5.09691001300806	(IGP2)	0.2206	[0.12-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30711851	NR	MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1			ENSG00000224587, ENSG00000225589, ENSG00000231135, ENSG00000137337, ENSG00000237095, ENSG00000228575, ENSG00000234012, ENSG00000206481, ENSG00000236522, ENSG00000236766, ENSG00000227899, ENSG00000224328, ENSG00000229681, ENSG00000231860, ENSG00000233883, ENSG00000224508	NA	NA	rs3094093-T	rs3094093	0	3094093	intron_variant	0	0.107418420152946	8e-06	5.09691001300806	(IGP2)	0.2231	[0.13-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.874157767431399	5e-06	5.30102999566398	(IGP2)	0.2092	[0.12-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31962664	NR	SKIV2L			ENSG00000225737	NA	NA	rs592229-G	rs592229	0	592229	intron_variant	0	0.370283129554656	9e-06	5.04575749056067	(IGP2)	0.1479	[0.083-0.213] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.63670095951417	2e-09	8.69897000433602	(IGP2)	0.1929	[0.13-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q31.1	5	132386057	NR	SLC22A5			ENSG00000197375	NA	NA	rs7731390-C	rs7731390	0	7731390	intron_variant	0	0.947724237786775	3e-06	5.52287874528034	(IGP2)	0.3771	[0.22-0.53] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.1	12	97134362	NR	AC007656.2			ENSG00000258131	NA	NA	rs7953959-C	rs7953959	0	7953959	intron_variant	0	0.49043844534413	8e-06	5.09691001300806	(IGP2)	0.1389	[0.078-0.2] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p16.1	4	6181457	NR	JAKMIP1, C4orf50, AC113615.2			ENSG00000152969, ENSG00000181215, ENSG00000287786	NA	NA	rs10937705-G	rs10937705	0	10937705	intron_variant	0	0.779354751351351	4e-06	5.39794000867204	(IGP20)	0.1717	[0.099-0.244] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q13.2	12	55031132	NR	NEUROD4 - OR9K1P	ENSG00000123307	ENSG00000196534		1115	81945	rs1386809-C	rs1386809	0	1386809	intergenic_variant	1	0.284827378378378	7e-06	5.15490195998574	(IGP20)	0.1576	[0.089-0.226] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p24.3	2	13889623	NR	LINC00276			ENSG00000230448	NA	NA	rs1598106-C	rs1598106	0	1598106	intron_variant	0	0.408824843693694	2e-07	6.69897000433602	(IGP20)	0.1642	[0.1-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.12	14	92757645	NR	LGMN - GOLGA5	ENSG00000100600	ENSG00000066455		8966	36660	rs7160685-C	rs7160685	0	7160685	regulatory_region_variant	1	0.700909354954955	8e-06	5.09691001300806	(IGP20)	0.1565	[0.088-0.225] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393609222420723	2e-06	5.69897000433602	(IGP21)	0.1501	[0.089-0.211] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p14	10	9526947	NR	AL138773.1 - HSP90AB7P	ENSG00000287120	ENSG00000235838		217175	195016	rs17515642-C	rs17515642	0	17515642	intergenic_variant	1	0.855118419830281	2e-06	5.69897000433602	(IGP21)	0.2258	[0.13-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q24.1	11	123002368	NR	BSX - AP003040.1	ENSG00000188909	ENSG00000213184		20534	15270	rs2126200-C	rs2126200	0	2126200	intergenic_variant	1	0.541753456007146	7e-06	5.15490195998574	(IGP21)	0.1392	[0.078-0.2] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393000049217002	1e-22	22	(IGP59)	0.3124	[0.25-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	47753582	NR	TBX21 - OSBPL7	ENSG00000073861	ENSG00000006025		7460	53790	rs12950390-C	rs12950390	0	12950390	intergenic_variant	1	0.252525314541387	3e-06	5.52287874528034	(IGP59)	0.1687	[0.098-0.239] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q24.31	12	122929802	NR	ABCB9			ENSG00000150967	NA	NA	rs2270788-C	rs2270788	0	2270788	3_prime_UTR_variant	0	0.0991554951230425	7e-06	5.15490195998574	(IGP59)	0.2364	[0.13-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32730008	NR	AL662789.1 - HLA-DQB3	ENSG00000232080	ENSG00000224197		10838	750	rs2859113-C	rs2859113	0	2859113	regulatory_region_variant	1	0.378328302013423	6e-08	7.22184874961636	(IGP59)	0.1817	[0.12-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.87438328769575	7e-06	5.15490195998574	(IGP59)	0.2057	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.636650594183445	1e-09	9	(IGP59)	0.1949	[0.13-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	47273752	NR	AC068234.1, ITGB3			ENSG00000259753, ENSG00000259207	NA	NA	rs7209700-G	rs7209700	0	7209700	intron_variant	0	0.308782806263982	4e-07	6.39794000867204	(IGP59)	0.1681	[0.1-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p11.2	11	45062980	NR	AC068858.1 - PRDM11	ENSG00000287984	ENSG00000019485		18927	32826	rs7951911-G	rs7951911	0	7951911	intergenic_variant	1	0.0838039874720358	8e-06	5.09691001300806	(IGP59)	0.2689	[0.15-0.39] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q34	13	113804266	NR	TMEM255B			ENSG00000184497	NA	NA	rs9329350-G	rs9329350	0	9329350	intron_variant	0	0.941389270067114	8e-06	5.09691001300806	(IGP59)	0.3006	[0.17-0.43] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q21.13	7	89065756	NR	ZNF804B			ENSG00000182348	NA	NA	rs10236237-T	rs10236237	0	10236237	intron_variant	0	0.267901504028648	7e-06	5.15490195998574	(IGP6)	0.1584	[0.089-0.228] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.394040135631155	5e-15	14.301029995664	(IGP6)	0.2482	[0.19-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31605179	NR	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		12173	5904	rs2844479-C	rs2844479	0	2844479	intergenic_variant	1	0.393631380483438	4e-06	5.39794000867204	(IGP6)	0.1506	[0.086-0.215] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q22.3	18	71712154	NR	AC090312.2 - LINC01899	ENSG00000265946	ENSG00000265352		46629	20461	rs2887004-G	rs2887004	0	2887004	intergenic_variant	1	0.180826079677708	6e-06	5.22184874961636	(IGP6)	0.1862	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.637609347358997	1e-08	8	(IGP6)	0.1817	[0.12-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q21.13	7	89065756	NR	ZNF804B			ENSG00000182348	NA	NA	rs10236237-T	rs10236237	0	10236237	intron_variant	0	0.26751565049416	6e-06	5.22184874961636	(IGP60)	0.16	[0.091-0.229] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393211372416891	3e-14	13.5228787452803	(IGP60)	0.2402	[0.18-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q26	4	116928293	NR	AC093765.3			ENSG00000287290	NA	NA	rs2389339-G	rs2389339	0	2389339	intron_variant	0	0.790576647349506	3e-06	5.52287874528034	(IGP60)	0.18	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31605179	NR	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		12173	5904	rs2844479-C	rs2844479	0	2844479	intergenic_variant	1	0.393698650943396	4e-06	5.39794000867204	(IGP60)	0.151	[0.087-0.215] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.637881567834681	5e-09	8.30102999566398	(IGP60)	0.1862	[0.12-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	95905518	NR	ELL2			ENSG00000118985	NA	NA	rs10069748-C	rs10069748	0	10069748	intron_variant	0	0.274419212661614	5e-06	5.30102999566398	(IGP61)	0.1539	[0.088-0.22] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q22.3	18	71698064	NR	AC090312.2 - LINC01899	ENSG00000265946	ENSG00000265352		32539	34551	rs11665307-C	rs11665307	0	11665307	intergenic_variant	1	0.173309217119929	3e-07	6.52287874528034	(IGP61)	0.2071	[0.13-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393162371823451	3e-17	16.5228787452803	(IGP61)	0.2676	[0.21-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	19p13.2	19	11544195	NR	CNN1			ENSG00000130176	NA	NA	rs11880637-T	rs11880637	0	11880637	intron_variant	0	0.011251	6e-06	5.22184874961636	(IGP61)	3.9379	[2.24-5.64] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q23	18	77926067	NR	RNA5SP461 - LINC01029	ENSG00000252260	ENSG00000265843		62500	44570	rs12455580-C	rs12455580	0	12455580	intergenic_variant	1	0.662638724030317	7e-06	5.15490195998574	(IGP61)	0.1605	[0.091-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p12	2	76996812	NR	AC079117.1, LRRTM4			ENSG00000234653, ENSG00000176204	NA	NA	rs1470506-C	rs1470506	0	1470506	intron_variant	0	0.594972305394561	6e-06	5.22184874961636	(IGP61)	0.1425	[0.081-0.204] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.2	9	27075717	NR	IFT74 - AL355432.1	ENSG00000096872	ENSG00000254396		12787	26913	rs1577330-G	rs1577330	0	1577330	intergenic_variant	1	0.245380581810076	4e-06	5.39794000867204	(IGP61)	0.1746	[0.1-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q42.12	1	225405225	NR	LBR			ENSG00000143815	NA	NA	rs16844846-G	rs16844846	0	16844846	intron_variant	0	0.0584601113241195	4e-06	5.39794000867204	(IGP61)	0.3154	[0.18-0.45] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31605179	NR	NCR3 - UQCRHP1	ENSG00000237808	ENSG00000229189		12173	5904	rs2844479-C	rs2844479	0	2844479	intergenic_variant	1	0.393516127507802	9e-06	5.04575749056067	(IGP61)	0.1445	[0.081-0.208] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50295636	NR	AC020743.3 - IKZF1	ENSG00000235620	ENSG00000185811		20014	8432	rs4917017-G	rs4917017	0	4917017	intergenic_variant	1	0.70576580729862	1e-08	8	(IGP70)	0.1974	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q11.22	20	33968971	NR	PIGPP3 - RALY-AS1	ENSG00000228958	ENSG00000285230		3395	11708	rs6059594-G	rs6059594	0	6059594	intergenic_variant	1	0.962797338540276	5e-06	5.30102999566398	(IGP70)	0.4906	[0.28-0.7] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	NR	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	4e-16	15.397940008672	(IGP70)	0.2754	[0.21-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q23.3	2	152580056	NR	FMNL2			ENSG00000157827	NA	NA	rs11675841-C	rs11675841	0	11675841	intron_variant	0	0.607345676902537	6e-06	5.22184874961636	(IGP71)	0.1448	[0.082-0.208] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13319976	NR	SEPHS1			ENSG00000086475	NA	NA	rs1747683-G	rs1747683	0	1747683	intron_variant	0	0.414548764129951	4e-07	6.39794000867204	(IGP71)	0.1618	[0.099-0.224] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	9e-17	16.0457574905607	(IGP71)	0.347	[0.27-0.43] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.639172889630619	9e-06	5.04575749056067	(IGP71)	0.1435	[0.08-0.207] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.3	1	68461830	NR	RPE65 - DEPDC1	ENSG00000116745	ENSG00000024526		11876	12322	rs435066-C	rs435066	0	435066	intergenic_variant	1	0.196103507788162	7e-06	5.15490195998574	(IGP71)	0.1774	[0.1-0.255] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q11.22	20	33968971	NR	PIGPP3 - RALY-AS1	ENSG00000228958	ENSG00000285230		3395	11708	rs6059594-G	rs6059594	0	6059594	intergenic_variant	1	0.962797338540276	4e-06	5.39794000867204	(IGP71)	0.4964	[0.29-0.71] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368179075211393	1e-08	8	(IGP71)	0.1829	[0.12-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	6e-16	15.2218487496164	(IGP71)	0.2737	[0.21-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13319976	NR	SEPHS1			ENSG00000086475	NA	NA	rs1747683-G	rs1747683	0	1747683	intron_variant	0	0.414510834817453	4e-07	6.39794000867204	(IGP72)	0.1616	[0.099-0.224] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189358691006233	9e-17	16.0457574905607	(IGP72)	0.3471	[0.27-0.43] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.3	1	68461830	NR	RPE65 - DEPDC1	ENSG00000116745	ENSG00000024526		11876	12322	rs435066-C	rs435066	0	435066	intergenic_variant	1	0.195968165182547	8e-06	5.09691001300806	(IGP72)	0.1763	[0.099-0.254] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q11.22	20	33968971	NR	PIGPP3 - RALY-AS1	ENSG00000228958	ENSG00000285230		3395	11708	rs6059594-G	rs6059594	0	6059594	intergenic_variant	1	0.962818623864648	7e-06	5.15490195998574	(IGP72)	0.4826	[0.27-0.69] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368120581032947	8e-09	8.09691001300806	(IGP72)	0.1863	[0.12-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q12	4	57073697	NR	IGFBP7			ENSG00000163453	NA	NA	rs10049992-G	rs10049992	0	10049992	intron_variant	0	0.201848923285199	8e-06	5.09691001300806	(IGP73)	0.2007	[0.11-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.873550828800713	6e-06	5.22184874961636	(IGP61)	0.206	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q22.31	6	123668596	NR	AL133257.1			ENSG00000285941	NA	NA	rs9490860-C	rs9490860	0	9490860	intron_variant	0	0.231696267498885	4e-06	5.39794000867204	(IGP61)	0.17	[0.098-0.242] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	19p13.2	19	11544195	NR	CNN1			ENSG00000130176	NA	NA	rs11880637-T	rs11880637	0	11880637	intron_variant	0	0.011251	6e-06	5.22184874961636	(IGP62)	3.8696	[2.2-5.54] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.3	8	141939370	NR	MIR1302-7 - AC104417.1	ENSG00000221768	ENSG00000254183		153057	28721	rs7845056-C	rs7845056	0	7845056	intergenic_variant	1	0.409235014686248	9e-06	5.04575749056067	(IGP48)	0.1776	[0.099-0.256] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	21q22.11	21	31923801	NR	HUNK			ENSG00000142149	NA	NA	rs11910494-G	rs11910494	0	11910494	intron_variant	0	0.288747077060134	8e-06	5.09691001300806	(IGP49)	0.1483	[0.083-0.213] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	78315910	NR	AC087645.2			ENSG00000267737	NA	NA	rs4789580-G	rs4789580	0	4789580	intron_variant	0	0.203878510467706	9e-06	5.04575749056067	(IGP49)	0.2275	[0.13-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q41	1	216330927	NR	USH2A			ENSG00000042781	NA	NA	rs7532570-G	rs7532570	0	7532570	intron_variant	0	0.0626114699331849	6e-06	5.22184874961636	(IGP49)	0.2924	[0.17-0.42] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p13.31	12	5642176	NR	ANO2			ENSG00000047617	NA	NA	rs2110166-C	rs2110166	0	2110166	intron_variant	0	0.983043522563177	5e-06	5.30102999566398	(IGP52)	0.5673	[0.32-0.81] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p13	20	4406487	NR	ADRA1D - AL139350.1	ENSG00000171873	ENSG00000236387		157200	15699	rs586446-C	rs586446	0	586446	regulatory_region_variant	1	0.118307047833935	5e-06	5.30102999566398	(IGP52)	0.2226	[0.13-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q22.3	11	107476551	NR	CWF19L2 - ALKBH8	ENSG00000152404	ENSG00000137760		18707	26175	rs11212260-C	rs11212260	0	11212260	intergenic_variant	1	0.0281428517133956	9e-06	5.04575749056067	(IGP53)	0.4437	[0.25-0.64] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p14.3	7	34657528	NR	NPSR1-AS1			ENSG00000197085	NA	NA	rs2530545-C	rs2530545	0	2530545	intron_variant	0	0.806018537605697	7e-06	5.15490195998574	(IGP53)	0.1859	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q13.1	8	65711997	NR	MTFR1			ENSG00000066855	NA	NA	rs10504390-G	rs10504390	0	10504390	intron_variant	0	0.0804795064530485	2e-07	6.69897000433602	(IGP54)	0.2877	[0.18-0.4] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q22.3	11	107476551	NR	CWF19L2 - ALKBH8	ENSG00000152404	ENSG00000137760		18707	26175	rs11212260-C	rs11212260	0	11212260	intergenic_variant	1	0.0281428517133956	7e-06	5.15490195998574	(IGP57)	0.4507	[0.25-0.65] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p13.3	9	36099402	RECK	RECK			ENSG00000122707	NA	NA	rs4878639-C	rs4878639	0	4878639	intron_variant	0	0.263725273253227	1e-06	6	(IGP57)	0.1734	[0.1-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.39336899642538	2e-19	18.698970004336	(IGP58)	0.2852	[0.22-0.35] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q22.3	18	71712154	NR	AC090312.2 - LINC01899	ENSG00000265946	ENSG00000265352		46629	20461	rs2887004-G	rs2887004	0	2887004	intergenic_variant	1	0.181545600983021	2e-06	5.69897000433602	(IGP58)	0.193	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p12	8	31176759	NR	AC009563.1			ENSG00000253961	NA	NA	rs11774682-C	rs11774682	0	11774682	non_coding_transcript_exon_variant	0	0.966250893300248	1e-06	6	(IGP59)	0.827	[0.49-1.16] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.636609333927775	7e-06	5.15490195998574	(IGP61)	0.143	[0.081-0.205] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q13.11	3	103731747	NR	TUBBP11 - RAP1BP2	ENSG00000243195	ENSG00000214405		100835	331292	rs2677247-C	rs2677247	0	2677247	intergenic_variant	1	0.602245139804096	9e-06	5.04575749056067	(IGP62)	0.1417	[0.079-0.204] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65291924	NR	AL355076.2			ENSG00000258760	NA	NA	rs7159888-G	rs7159888	0	7159888	intron_variant	0	0.550559034728406	2e-06	5.69897000433602	(IGP62)	0.1465	[0.086-0.207] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q23	18	77926067	NR	RNA5SP461 - LINC01029	ENSG00000252260	ENSG00000265843		62500	44570	rs12455580-C	rs12455580	0	12455580	intergenic_variant	1	0.662723558771149	2e-06	5.69897000433602	(IGP65)	0.1716	[0.1-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.872971129118433	6e-07	6.22184874961636	(IGP65)	0.2253	[0.14-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	81261988	SLC38A10	SLC38A10			ENSG00000157637	NA	NA	rs7224668-C	rs7224668	0	7224668	intron_variant	0	0.524575415405165	3e-08	7.52287874528034	(IGP31)	0.1729	[0.11-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176763000890472	4e-07	6.39794000867204	(IGP31)	0.2226	[0.14-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q22	17	58236543	NR	LPO			ENSG00000167419	NA	NA	rs8067912-C	rs8067912	0	8067912	intron_variant	0	0.0307230178539626	5e-07	6.30102999566398	(IGP31)	0.4565	[0.28-0.63] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699319077951002	3e-37	36.5228787452803	(IGP32)	0.4479	[0.38-0.52] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	95926809	NR	ELL2			ENSG00000118985	NA	NA	rs11738945-C	rs11738945	0	11738945	intron_variant	0	0.785892907349666	1e-06	6	(IGP32)	0.1818	[0.11-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q26	6	161893889	NR	PRKN			ENSG00000185345	NA	NA	rs12207186-T	rs12207186	0	12207186	intron_variant	0	0.0677100908685969	5e-06	5.30102999566398	(IGP32)	0.2882	[0.16-0.41] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189579642030276	1e-12	12	(IGP62)	0.2948	[0.21-0.38] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.3	1	68461830	NR	RPE65 - DEPDC1	ENSG00000116745	ENSG00000024526		11876	12322	rs435066-C	rs435066	0	435066	intergenic_variant	1	0.195964786286732	4e-06	5.39794000867204	(IGP62)	0.1812	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q11.22	20	33968971	NR	PIGPP3 - RALY-AS1	ENSG00000228958	ENSG00000285230		3395	11708	rs6059594-G	rs6059594	0	6059594	intergenic_variant	1	0.962780757212823	3e-06	5.52287874528034	(IGP62)	0.4999	[0.29-0.71] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368343116206589	8e-12	11.0969100130081	(IGP62)	0.2202	[0.16-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q13.3	11	69787644	NR	FGF4 - FGF3	ENSG00000075388	ENSG00000186895		12303	22324	rs10796849-C	rs10796849	0	10796849	intergenic_variant	1	0.111934	6e-06	5.22184874961636	(IGP73)	0.6132	[0.35-0.88] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q24.1	10	95541247	NR	SORBS1			ENSG00000095637	NA	NA	rs11188352-G	rs11188352	0	11188352	intron_variant	0	0.0425983446750903	3e-06	5.52287874528034	(IGP73)	0.4377	[0.25-0.62] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p13.31	12	5642176	NR	ANO2			ENSG00000047617	NA	NA	rs2110166-C	rs2110166	0	2110166	intron_variant	0	0.983043627256318	6e-06	5.22184874961636	(IGP73)	0.562	[0.32-0.81] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q14.1	12	62492343	NR	MON2			ENSG00000061987	NA	NA	rs7301016-G	rs7301016	0	7301016	intron_variant	0	0.206214031137184	8e-06	5.09691001300806	(IGP73)	0.1687	[0.095-0.243] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q24.3	6	147438398	NR	YAP1P1 - SAMD5	ENSG00000220494	ENSG00000203727		30117	70292	rs9403856-C	rs9403856	0	9403856	intergenic_variant	1	0.861471281137184	7e-07	6.15490195998574	(IGP73)	0.341	[0.21-0.48] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33122647	NR	B4GALT1			ENSG00000086062	NA	NA	rs10113903-C	rs10113903	0	10113903	intron_variant	0	0.308537513851653	7e-06	5.15490195998574	(IGP74)	0.1529	[0.086-0.22] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q23	3	139197551	NR	MRPS22			ENSG00000175110	NA	NA	rs11706018-C	rs11706018	0	11706018	intron_variant	0	0.934284044682752	9e-06	5.04575749056067	(IGP74)	0.2773	[0.15-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q32.1	1	205514467	NR	CDK18			ENSG00000117266	NA	NA	rs12127944-C	rs12127944	0	12127944	intron_variant	0	0.911099744252874	6e-06	5.22184874961636	(IGP74)	0.3115	[0.18-0.45] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q12.1	16	49618868	NR	ZNF423			ENSG00000102935	NA	NA	rs16944158-G	rs16944158	0	16944158	intron_variant	0	0.271065156389634	4e-06	5.39794000867204	(IGP74)	0.162	[0.093-0.231] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	107951753	LAMB1	LAMB1			ENSG00000091136	NA	NA	rs2072209-G	rs2072209	0	2072209	intron_variant	0	0.0584063163538874	2e-06	5.69897000433602	(IGP74)	0.3125	[0.18-0.44] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q28.1	4	127545545	NR	AC097462.3			ENSG00000287021	NA	NA	rs2090104-G	rs2090104	0	2090104	intron_variant	0	0.335522302949062	5e-06	5.30102999566398	(IGP74)	0.1533	[0.087-0.219] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.190211496872207	2e-08	7.69897000433602	(IGP74)	0.2357	[0.15-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q26.12	10	120283977	NR	AL355298.1 - RPL21P16	ENSG00000223455	ENSG00000220842		213818	70724	rs11199254-C	rs11199254	0	11199254	intergenic_variant	1	0.994468962750716	2e-06	5.69897000433602	(IGP40)	1.5588	[0.91-2.21] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	1e-10	10	(IGP40)	0.2653	[0.18-0.35] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q22.1	6	114748553	NR	AL138830.1 - AL590550.1	ENSG00000226079	ENSG00000287097		203218	74441	rs6928844-C	rs6928844	0	6928844	regulatory_region_variant	1	0.828248277703605	7e-06	5.15490195998574	(IGP40)	0.2768	[0.16-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q21.3	5	108396257	NR	AC008462.1			ENSG00000286503	NA	NA	rs1001579-G	rs1001579	0	1001579	intron_variant	0	0.167464012461059	7e-06	5.15490195998574	(IGP43)	0.182	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836731980863373	3e-10	9.52287874528034	(IGP43)	0.2804	[0.19-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	19q13.42	19	53276773	NR	AC092070.4 - FAM90A27P	ENSG00000269758	ENSG00000189348		5841	4786	rs2965260-C	rs2965260	0	2965260	intergenic_variant	1	0.898395713962946	9e-06	5.04575749056067	(IGP44)	0.2293	[0.13-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q11.21	8	50472427	NR	SNTG1			ENSG00000147481	NA	NA	rs13272236-G	rs13272236	0	13272236	intron_variant	0	0.0367158118323747	6e-07	6.22184874961636	(IGP45)	0.8377	[0.51-1.17] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q31.2	1	191970658	NR	LINC02770			ENSG00000228215	NA	NA	rs17403780-T	rs17403780	0	17403780	intron_variant	0	0.910603886426346	6e-06	5.22184874961636	(IGP45)	0.3134	[0.18-0.45] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	107802941	NR	SLC26A3			ENSG00000091138	NA	NA	rs4730268-C	rs4730268	0	4730268	intron_variant	0	0.783243083222074	5e-06	5.30102999566398	(IGP48)	0.1679	[0.096-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Factor VII	886 European ancestry individuals	NA	13q34	13	113105720	MCF2L, AB116074, AK092739, AK123267, AB002360, F7, CR603372, F10, PROZ	MCF2L - F7	ENSG00000126217	ENSG00000057593		5978	68	rs561241-?	rs561241	0	561241	TF_binding_site_variant	1	0.12	5e-16	15.301029995664		NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Factor VII	886 European ancestry individuals	NA	7p22.2	7	4371578	intergenic	SDK1 - CYP3A54P	ENSG00000146555	ENSG00000261809		102578	140381	rs10488360-?	rs10488360	0	10488360	intergenic_variant	1	0.30	7e-06	5.15490195998574		NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Factor VII	886 European ancestry individuals	NA	1p36.32	1	4255144	intergenic	EEF1DP6 - LINC01777	ENSG00000229280	ENSG00000235054		79245	156883	rs966321-?	rs966321	0	966321	intergenic_variant	1	0.47	8e-06	5.09691001300806		NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Factor VII	886 European ancestry individuals	NA	3p26.1	3	7941140	intergenic	AC077690.1 - LMCD1-AS1	ENSG00000270207	ENSG00000227110		150658	10123	rs4591494-?	rs4591494	0	4591494	intergenic_variant	1	0.19	9e-06	5.04575749056067		NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	2p16.2	2	53010182	intergenic	AC010967.1 - AC069157.2	ENSG00000228033	ENSG00000251942		48730	460265	rs1160297-?	rs1160297	0	1160297	intergenic_variant	1	0.43	1e-06	6	(Hgb)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	8q24.13	8	121896264	intergenic	HAS2-AS1			ENSG00000248690	NA	NA	rs7844723-?	rs7844723	0	7844723	intron_variant	0	0.45	2e-06	5.69897000433602	(Hgb)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	11q12.1	11	56698623	OR5AR1, OR9G1, OR9G4, OR5AP2	AP004245.1 - OR9G1	ENSG00000238041	ENSG00000261958		7900	472	rs1397048-?	rs1397048	0	1397048	intergenic_variant	1	0.4	7e-08	7.15490195998574	(MCH)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	11q24.1	11	122318757	intergenic	MIR100HG			ENSG00000255248	NA	NA	rs565229-?	rs565229	0	565229	intron_variant	0	0.10	4e-06	5.39794000867204	(pltcoll)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	4p15.33	4	13792792	intergenic	LINC01182			ENSG00000250634	NA	NA	rs10489087-?	rs10489087	0	10489087	intron_variant	0	0.13	5e-06	5.30102999566398	(RBCC)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	6q25.1	6	149272784	MAP3K7IP2	TAB2			ENSG00000055208	NA	NA	rs727979-?	rs727979	0	727979	intron_variant	0	0.14	8e-06	5.09691001300806	(RBCC)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	20p12.3	20	7571857	intergenic	MIR8062 - RN7SL547P	ENSG00000278159	ENSG00000240584		200165	61705	rs6108011-?	rs6108011	0	6108011	regulatory_region_variant	1	0.28	6e-06	5.22184874961636	(RBCC)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	10p11.21	10	37270652	ANKRD30A	LINC00993, ANKRD30A			ENSG00000235687, ENSG00000148513	NA	NA	rs1200821-?	rs1200821	0	1200821	intron_variant	0	0.47	6e-06	5.22184874961636	(MCH)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	14q32.2	14	98176235	intergenic	AL163932.1			ENSG00000259097	NA	NA	rs10484128-?	rs10484128	0	10484128	intron_variant	0	0.15	6e-06	5.22184874961636	(pltadp)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	5q21.1	5	99445399	intergenic	LINC02062 - AC114324.2	ENSG00000248489	ENSG00000249444		450386	44160	rs1829883-?	rs1829883	0	1829883	intergenic_variant	1	0.41	6e-06	5.22184874961636	(MCH)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	2p16.2	2	53038991	intergenic	AC010967.1 - AC069157.2	ENSG00000228033	ENSG00000251942		77539	431456	rs2357013-?	rs2357013	0	2357013	intergenic_variant	1	0.45	6e-06	5.22184874961636	(Hgb)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	5q21.3	5	110161259	intergenic	PGAM5P1 - TMEM232	ENSG00000253224	ENSG00000186952		275836	127974	rs4460176-?	rs4460176	0	4460176	regulatory_region_variant	1	0.29	3e-06	5.52287874528034	(PAI-1)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	14q21.3	14	47394632	MAMDC1	MDGA2			ENSG00000139915	NA	NA	rs7159841-?	rs7159841	0	7159841	intron_variant	0	0.21	2e-07	6.69897000433602	(Viscosity)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	6q25.1	6	149204470	intergenic	AL603766.1 - AL031056.1	ENSG00000219487	ENSG00000228408		91798	13456	rs636864-?	rs636864	0	636864	intergenic_variant	1	0.21	6e-06	5.22184874961636	(RBCC)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	12q14.2	12	63051312	intergenic	LDHAL6CP - RSL24D1P5	ENSG00000250517	ENSG00000257664		44410	3963	rs10506458-?	rs10506458	0	10506458	intergenic_variant	1	0.13	5e-06	5.30102999566398	(pltcoll)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	1p31.1	1	71605446	NEGR1	NEGR1			ENSG00000172260	NA	NA	rs10493485-?	rs10493485	0	10493485	intron_variant	0	0.29	2e-06	5.69897000433602	(tPA)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	1p34.3	1	37493212	FLJ11730, BC016328	MEAF6			ENSG00000163875	NA	NA	rs9253-?	rs9253	0	9253	3_prime_UTR_variant	0	0.18	4e-06	5.39794000867204	(RBCC)	NA		Affymetrix [70897]	N
2008-08-28	17903294	Yang Q	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903294	Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.	Hemostatic factors and hematological phenotypes	Up to 1,062 European ancestry individuals	NA	1q23.2	1	159484147	OR10J1, OR10J5	LINC02819 - OR10J5	ENSG00000224943	ENSG00000184155		771	50931	rs4133289-?	rs4133289	0	4133289	intergenic_variant	1	0.19	2e-07	6.69897000433602	(Hgb)	NA		Affymetrix [70897]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q24.1	15	73457267	NR	REC114			ENSG00000183324	NA	NA	rs11635553-G	rs11635553	0	11635553	intron_variant	0	0.992814619440459	6e-06	5.22184874961636	(IGP75)	1.0594	[0.6-1.52] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q23	3	139197551	NR	MRPS22			ENSG00000175110	NA	NA	rs11706018-C	rs11706018	0	11706018	intron_variant	0	0.934430632634864	7e-06	5.15490195998574	(IGP75)	0.2799	[0.16-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q32.1	1	205514467	NR	CDK18			ENSG00000117266	NA	NA	rs12127944-C	rs12127944	0	12127944	intron_variant	0	0.911226779053085	4e-06	5.39794000867204	(IGP75)	0.3151	[0.18-0.45] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836657880517164	4e-06	5.39794000867204	(IGP75)	0.2064	[0.12-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	107951753	LAMB1	LAMB1			ENSG00000091136	NA	NA	rs2072209-G	rs2072209	0	2072209	intron_variant	0	0.0582759937583593	2e-07	6.69897000433602	(IGP75)	0.3382	[0.21-0.47] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q12.1	16	49609655	NR	ZNF423			ENSG00000102935	NA	NA	rs2080501-G	rs2080501	0	2080501	intron_variant	0	0.532295847079804	4e-06	5.39794000867204	(IGP75)	0.1421	[0.082-0.203] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189826451627285	4e-09	8.39794000867204	(IGP75)	0.2454	[0.16-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	38782370	NR	SUN2, DNAL4			ENSG00000100242, ENSG00000100246	NA	NA	rs738144-G	rs738144	0	738144	intron_variant	0	0.204838376727597	7e-06	5.15490195998574	(IGP75)	0.1878	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p21	2	46323630	NR	EPAS1			ENSG00000116016	NA	NA	rs7582701-C	rs7582701	0	7582701	intron_variant	0	0.0373185578689255	2e-06	5.69897000433602	(IGP75)	0.4488	[0.27-0.63] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q12	14	24139938	NR	AL136295.2, EMC9, EMC9			ENSG00000259321, ENSG00000285377, ENSG00000100908	NA	NA	rs8010715-C	rs8010715	0	8010715	non_coding_transcript_exon_variant	0	0.262775408381632	9e-06	5.04575749056067	(IGP75)	0.1664	[0.093-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30698892	NR	RPL7P4 - MDC1	ENSG00000238255	ENSG00000206481		1357	915	rs9468811-C	rs9468811	0	9468811	intergenic_variant	1	0.937641317877842	2e-06	5.69897000433602	(IGP75)	0.3304	[0.19-0.47] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q24.1	15	73457267	NR	REC114			ENSG00000183324	NA	NA	rs11635553-G	rs11635553	0	11635553	intron_variant	0	0.99282491474212	9e-06	5.04575749056067	(IGP76)	1.0357	[0.58-1.49] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	107951753	LAMB1	LAMB1			ENSG00000091136	NA	NA	rs2072209-G	rs2072209	0	2072209	intron_variant	0	0.0581724966622163	8e-06	5.09691001300806	(IGP76)	0.2906	[0.16-0.42] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q12.1	16	49609655	NR	ZNF423			ENSG00000102935	NA	NA	rs2080501-G	rs2080501	0	2080501	intron_variant	0	0.532905723186471	5e-06	5.30102999566398	(IGP76)	0.141	[0.081-0.201] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	2e-08	7.69897000433602	(IGP76)	0.2333	[0.15-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q21.31	12	82068447	NR	AC011602.1 - CCDC59	ENSG00000258193	ENSG00000133773		69485	155234	rs7137515-G	rs7137515	0	7137515	intergenic_variant	1	0.260927853582555	6e-06	5.22184874961636	(IGP76)	0.1637	[0.093-0.235] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p21	2	46323630	NR	EPAS1			ENSG00000116016	NA	NA	rs7582701-C	rs7582701	0	7582701	intron_variant	0	0.0372783807743658	4e-06	5.39794000867204	(IGP76)	0.4309	[0.25-0.61] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30698892	NR	RPL7P4 - MDC1	ENSG00000238255	ENSG00000206481		1357	915	rs9468811-C	rs9468811	0	9468811	intergenic_variant	1	0.937308425901202	5e-07	6.30102999566398	(IGP76)	0.3469	[0.21-0.48] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.394003751805054	6e-06	5.22184874961636	(IGP77)	0.1425	[0.081-0.204] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p21.1	7	20845476	NR	LINC01162			ENSG00000232790	NA	NA	rs13245023-C	rs13245023	0	13245023	intron_variant	0	0.964100804151624	9e-06	5.04575749056067	(IGP77)	0.4218	[0.24-0.61] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.1	3	150369221	NR	AC018545.1 - TSC22D2	ENSG00000286501	ENSG00000196428		26011	39114	rs1012583-G	rs1012583	0	1012583	intergenic_variant	1	0.702573039608367	4e-06	5.39794000867204	(IGP8)	0.1552	[0.089-0.221] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p14.1	3	64188225	NR	PRICKLE2-AS3, PRICKLE2			ENSG00000226017, ENSG00000163637	NA	NA	rs1035275-C	rs1035275	0	1035275	intron_variant	0	0.444727228304406	9e-06	5.04575749056067	(IGP8)	0.1416	[0.079-0.204] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q25	4	110306660	NR	ZBED1P1 - ENPEP	ENSG00000250304	ENSG00000138792		13087	59073	rs13148252-G	rs13148252	0	13148252	regulatory_region_variant	1	0.745779246105919	6e-06	5.22184874961636	(IGP8)	0.171	[0.097-0.245] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.2	22	43228759	NR	SCUBE1			ENSG00000159307	NA	NA	rs139014-C	rs139014	0	139014	intron_variant	0	0.167018170449488	5e-06	5.30102999566398	(IGP8)	0.1994	[0.11-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.1	3	150979421	NR	AC020636.1, CLRN1-AS1			ENSG00000243273, ENSG00000239265	NA	NA	rs16863118-C	rs16863118	0	16863118	intron_variant	0	0.836539205162439	8e-06	5.09691001300806	(IGP8)	0.1835	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.3	1	68461830	NR	RPE65 - DEPDC1	ENSG00000116745	ENSG00000024526		11876	12322	rs435066-C	rs435066	0	435066	intergenic_variant	1	0.195829321603564	7e-06	5.15490195998574	(IGP63)	0.1765	[0.1-0.253] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39439582	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268		2522	17430	rs4821897-G	rs4821897	0	4821897	regulatory_region_variant	1	0.707128727839644	3e-12	11.5228787452803	(IGP63)	0.2388	[0.17-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368316756347439	2e-13	12.698970004336	(IGP63)	0.2363	[0.17-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q34.2	9	133810892	NR	VAV2			ENSG00000160293	NA	NA	rs7021663-C	rs7021663	0	7021663	intron_variant	0	0.209934371046771	3e-06	5.52287874528034	(IGP63)	0.1807	[0.1-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q42.2	1	234590610	NR	AL161640.1 - U8	ENSG00000230404	ENSG00000238963		20522	2665	rs11581667-C	rs11581667	0	11581667	intergenic_variant	1	0.745277716510903	4e-06	5.39794000867204	(IGP64)	0.196	[0.11-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13319976	NR	SEPHS1			ENSG00000086475	NA	NA	rs1747683-G	rs1747683	0	1747683	intron_variant	0	0.414548764129951	3e-07	6.52287874528034	(IGP64)	0.1637	[0.1-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	2e-14	13.698970004336	(IGP64)	0.3184	[0.24-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	53256409	NR	AC026477.1 - AC027329.1	ENSG00000213940	ENSG00000285831		49233	41463	rs27323-G	rs27323	0	27323	intergenic_variant	1	0.421661209612817	9e-06	5.04575749056067	(IGP64)	0.1399	[0.078-0.202] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.33	22	50463961	NR	SBF1			ENSG00000100241	NA	NA	rs5771040-G	rs5771040	0	5771040	intron_variant	0	0.660043690698709	2e-06	5.69897000433602	(IGP64)	0.1595	[0.093-0.226] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368179075211393	2e-07	6.69897000433602	(IGP64)	0.1714	[0.11-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	3e-08	7.52287874528034	(IGP64)	0.1872	[0.12-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393717723953695	1e-10	10	(IGP65)	0.2023	[0.14-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	19p13.2	19	11544195	NR	CNN1			ENSG00000130176	NA	NA	rs11880637-T	rs11880637	0	11880637	intron_variant	0	0.011251	6e-06	5.22184874961636	(IGP65)	3.9206	[2.22-5.62] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q12.1	2	102772135	NR	TMEM182			ENSG00000170417	NA	NA	rs12465996-C	rs12465996	0	12465996	intron_variant	0	0.864479920980926	5e-06	5.30102999566398	(IGP1)	0.2431	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17p11.2	17	17239582	NR	FLCN - ACTG1P24	ENSG00000154803	ENSG00000226359		2394	2428	rs12600635-G	rs12600635	0	12600635	intergenic_variant	1	0.145264718437784	2e-07	6.69897000433602	(IGP1)	0.2272	[0.14-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p13.31	12	7182621	PEX5	AC018653.1			ENSG00000255572	NA	NA	rs12828421-C	rs12828421	0	12828421	intron_variant	0	0.513425077202543	9e-07	6.04575749056067	(IGP1)	0.1591	[0.096-0.223] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32706960	NR	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		5	11045	rs1794265-C	rs1794265	0	1794265	intergenic_variant	1	0.945894807901907	8e-06	5.09691001300806	(IGP1)	0.3014	[0.17-0.43] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	21q22.3	21	41421864	NR	MX1			ENSG00000157601	NA	NA	rs459482-C	rs459482	0	459482	5_prime_UTR_variant	0	0.594937723887375	2e-06	5.69897000433602	(IGP1)	0.1509	[0.089-0.213] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176843186191537	9e-15	14.0457574905607	(IGP32)	0.3392	[0.25-0.42] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30830214	NR	LINC00243			ENSG00000214894	NA	NA	rs7749924-C	rs7749924	0	7749924	intron_variant	0	0.851598582628062	8e-06	5.09691001300806	(IGP32)	0.2204	[0.12-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p24.3	3	22129805	NR	ZNF385D			ENSG00000151789	NA	NA	rs6797769-T	rs6797769	0	6797769	intron_variant	0	0.548041472743521	3e-06	5.52287874528034	(IGP74)	0.1661	[0.097-0.235] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p21	2	46323630	NR	EPAS1			ENSG00000116016	NA	NA	rs7582701-C	rs7582701	0	7582701	intron_variant	0	0.037394344593387	4e-06	5.39794000867204	(IGP74)	0.4338	[0.25-0.62] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30698892	NR	RPL7P4 - MDC1	ENSG00000238255	ENSG00000206481		1357	915	rs9468811-C	rs9468811	0	9468811	intergenic_variant	1	0.937725588025022	3e-06	5.52287874528034	(IGP74)	0.3262	[0.19-0.46] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33128023	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813951-G	rs10813951	0	10813951	intron_variant	0	0.262766006241641	4e-07	6.39794000867204	(IGP75)	0.1812	[0.11-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q32	9	112925455	NR	SLC46A2 - ZNF883	ENSG00000119457	ENSG00000285447		34579	71665	rs10817408-C	rs10817408	0	10817408	regulatory_region_variant	1	0.149506685242978	6e-06	5.22184874961636	(IGP75)	0.2271	[0.13-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698883767483296	4e-31	30.397940008672	(IGP24)	0.4048	[0.34-0.47] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33124874	B4GALT1	B4GALT1			ENSG00000086062	NA	NA	rs12342831-C	rs12342831	0	12342831	intron_variant	0	0.262634642316258	3e-10	9.52287874528034	(IGP24)	0.2233	[0.15-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q23.1	10	82659654	NR	NRG3			ENSG00000185737	NA	NA	rs2219937-G	rs2219937	0	2219937	intron_variant	0	0.984667459331848	4e-06	5.39794000867204	(IGP24)	0.7496	[0.43-1.07] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q22.1	4	91996064	NR	AC093810.1 - PMPCAP1	ENSG00000249052	ENSG00000248817		91729	186413	rs6853847-C	rs6853847	0	6853847	intergenic_variant	1	0.0304513777282851	2e-06	5.69897000433602	(IGP24)	0.4788	[0.28-0.67] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176834709131403	4e-16	15.397940008672	(IGP24)	0.3532	[0.27-0.44] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.3	10	63112651	NR	RNU6-543P - AL590502.1	ENSG00000199446	ENSG00000224301		2405	11278	rs10822136-C	rs10822136	0	10822136	regulatory_region_variant	1	0.805465852941177	7e-07	6.15490195998574	(IGP25)	0.2085	[0.13-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p15.2	4	21453634	NR	KCNIP4			ENSG00000185774	NA	NA	rs11942476-C	rs11942476	0	11942476	intron_variant	0	0.855854377005348	6e-06	5.22184874961636	(IGP25)	0.2144	[0.12-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q24.33	12	129162027	NR	TMEM132D			ENSG00000151952	NA	NA	rs12580240-G	rs12580240	0	12580240	intron_variant	0	0.0139850911701364	2e-06	5.69897000433602	(IGP25)	0.895	[0.53-1.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p12.1	10	25713319	NR	LINC00836			ENSG00000280809	NA	NA	rs2504183-G	rs2504183	0	2504183	intron_variant	0	0.71933817201426	7e-06	5.15490195998574	(IGP25)	0.1943	[0.11-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q12	20	40849893	NR	AL035665.2 - RNA5SP484	ENSG00000286972	ENSG00000238908		91257	4226	rs6102185-G	rs6102185	0	6102185	intergenic_variant	1	0.422812170677362	2e-06	5.69897000433602	(IGP25)	0.1489	[0.088-0.21] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p11.23	20	20653462	NR	RALGAPA2			ENSG00000188559	NA	NA	rs6132333-C	rs6132333	0	6132333	intron_variant	0	0.0250948889928699	1e-06	6	(IGP25)	0.5296	[0.31-0.75] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32146738	PRRT1	FKBPL - PRRT1	ENSG00000230907	ENSG00000227122		16450	1621	rs9296009-T	rs9296009	0	9296009	regulatory_region_variant	1	0.19676420855615	4e-06	5.39794000867204	(IGP25)	0.1773	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q32.1	2	185160008	NR	ZNF804A - AC009315.1	ENSG00000170396	ENSG00000286797		220516	265055	rs11678036-C	rs11678036	0	11678036	intergenic_variant	1	0.390262875779163	6e-06	5.22184874961636	(IGP26)	0.1459	[0.082-0.209] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698789225734639	2e-13	12.698970004336	(IGP26)	0.2563	[0.19-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33124874	B4GALT1	B4GALT1			ENSG00000086062	NA	NA	rs12342831-C	rs12342831	0	12342831	intron_variant	0	0.262517754229742	3e-11	10.5228787452803	(IGP26)	0.2358	[0.17-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q21.1	5	100966102	NR	ST8SIA4 - RN7SL802P	ENSG00000113532	ENSG00000277506		62820	615728	rs17161553-C	rs17161553	0	17161553	intergenic_variant	1	0.00759786255756579	1e-06	6	(IGP26)	1.6947	[1.01-2.38] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299146468388246	2e-10	9.69897000433602	(IGP62)	0.2148	[0.15-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	47232327	NR	MYL4 - ITGB3	ENSG00000198336	ENSG00000259207		8648	21519	rs11079764-G	rs11079764	0	11079764	intergenic_variant	1	0.51337114610245	5e-06	5.30102999566398	(IGP63)	0.1833	[0.1-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p13	3	72460120	NR	RYBP - AC104435.2	ENSG00000281766	ENSG00000244345		13499	44686	rs11128271-C	rs11128271	0	11128271	intergenic_variant	1	0.936242533184855	6e-06	5.22184874961636	(IGP63)	0.3063	[0.17-0.44] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393668566146993	3e-08	7.52287874528034	(IGP63)	0.1747	[0.11-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q14.3	2	124499159	NR	CNTNAP5			ENSG00000155052	NA	NA	rs11899928-C	rs11899928	0	11899928	intron_variant	0	0.0215184841870824	8e-06	5.09691001300806	(IGP63)	0.6871	[0.39-0.99] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	21q22.3	21	42093370	NR	UMODL1			ENSG00000177398	NA	NA	rs1475911-C	rs1475911	0	1475911	intron_variant	0	0.154651563028953	9e-06	5.04575749056067	(IGP63)	0.2012	[0.11-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p22	8	12834362	NR	LINC00681 - TRMT9B	ENSG00000255494	ENSG00000250305		16071	111280	rs17120471-C	rs17120471	0	17120471	intergenic_variant	1	0.101965395991091	6e-06	5.22184874961636	(IGP63)	0.2366	[0.13-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189663332739421	4e-09	8.39794000867204	(IGP63)	0.2445	[0.16-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q24.1	16	86647390	NR	AC009154.1			ENSG00000261161	NA	NA	rs300032-G	rs300032	0	300032	intron_variant	0	0.146304785746102	9e-08	7.04575749056067	(IGP63)	0.2433	[0.15-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p22.1	1	94256104	NR	ARHGAP29, ARHGAP29-AS1			ENSG00000137962, ENSG00000226835	NA	NA	rs12750249-C	rs12750249	0	12750249	intron_variant	0	0.256632781737194	4e-06	5.39794000867204	(IGP32)	0.165	[0.095-0.235] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.23	8	136837768	NR	LINC02055			ENSG00000254101	NA	NA	rs16906415-G	rs16906415	0	16906415	intron_variant	0	0.107822580400891	6e-06	5.22184874961636	(IGP32)	0.2296	[0.13-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5p14.1	5	25419980	NR	AC022140.1			ENSG00000248605	NA	NA	rs1904173-G	rs1904173	0	1904173	intron_variant	0	0.86006371714922	7e-06	5.15490195998574	(IGP32)	0.201	[0.11-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q23.2	11	114516380	NR	NXPE2P1 - AC020549.3	ENSG00000255982	ENSG00000270204		2949	1484	rs4466877-G	rs4466877	0	4466877	intergenic_variant	1	0.880799535011136	9e-07	6.04575749056067	(IGP32)	0.2413	[0.15-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p11.23	20	20653462	NR	RALGAPA2			ENSG00000188559	NA	NA	rs6132333-C	rs6132333	0	6132333	intron_variant	0	0.0250837167483296	3e-06	5.52287874528034	(IGP32)	0.5085	[0.29-0.72] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q23.1	6	130565292	NR	TMEM200A - Y_RNA	ENSG00000164484	ENSG00000265852		122229	8704	rs9492645-G	rs9492645	0	9492645	intergenic_variant	1	0.947434826924789	5e-06	5.30102999566398	(IGP8)	0.3363	[0.19-0.48] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.1	1	78711183	NR	AC104837.2 - AC104837.1	ENSG00000238015	ENSG00000235400		44488	37890	rs4650376-C	rs4650376	0	4650376	intergenic_variant	1	0.126317908441268	2e-06	5.69897000433602	(IGP21)	0.2355	[0.14-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.22	8	131318469	NR	AC104257.1 - SNORA72	ENSG00000253507	ENSG00000207249		837	114307	rs10108033-C	rs10108033	0	10108033	intergenic_variant	1	0.990183	3e-06	5.52287874528034	(IGP22)	2.8474	[1.65-4.05] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33125806	NR	B4GALT1			ENSG00000086062	NA	NA	rs10758189-C	rs10758189	0	10758189	intron_variant	0	0.31099528984862	2e-06	5.69897000433602	(IGP22)	0.1679	[0.099-0.236] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p14.3	11	25468936	NR	AC087373.1 - RPL36AP40	ENSG00000255368	ENSG00000240298		327913	119539	rs10834691-G	rs10834691	0	10834691	intergenic_variant	1	0.459134585485307	4e-06	5.39794000867204	(IGP22)	0.1479	[0.085-0.211] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698789225734639	9e-07	6.04575749056067	(IGP22)	0.1723	[0.1-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q13	6	70031317	NR	COL19A1			ENSG00000082293	NA	NA	rs3793039-G	rs3793039	0	3793039	intron_variant	0	0.25306153873553	2e-06	5.69897000433602	(IGP22)	0.2388	[0.14-0.34] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q12	20	40842787	NR	AL035665.2 - RNA5SP484	ENSG00000286972	ENSG00000238908		84151	11332	rs6072161-C	rs6072161	0	6072161	intergenic_variant	1	0.573146759127338	3e-07	6.52287874528034	(IGP22)	0.1589	[0.098-0.22] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q24.3	14	74860740	NR	PROX2			ENSG00000119608	NA	NA	rs722599-C	rs722599	0	722599	intron_variant	0	0.4301501460374	8e-06	5.09691001300806	(IGP22)	0.1395	[0.078-0.201] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.298923567230632	5e-10	9.30102999566398	(IGP22)	0.2099	[0.14-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p15.33	4	12578222	NR	RNU6-578P - ECM1P2	ENSG00000212282	ENSG00000249995		265532	60864	rs10002492-G	rs10002492	0	10002492	intergenic_variant	1	0.167227182224207	8e-06	5.09691001300806	(IGP23)	0.1837	[0.1-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699064071907101	6e-11	10.2218487496164	(IGP23)	0.2297	[0.16-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.1	7	53059866	NR	POM121L12 - HAUS6P1	ENSG00000221900	ENSG00000227344		22941	127522	rs1174864-G	rs1174864	0	1174864	intergenic_variant	1	0.49190341581063	5e-06	5.30102999566398	(IGP23)	0.1417	[0.081-0.203] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.1	17	73811574	NR	LINC00469			ENSG00000177338	NA	NA	rs12451840-C	rs12451840	0	12451840	intron_variant	0	0.0417941590759076	3e-06	5.52287874528034	(IGP23)	0.7321	[0.42-1.04] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p13	3	71364894	NR	AC097634.4, FOXP1			ENSG00000285708, ENSG00000114861	NA	NA	rs13072512-G	rs13072512	0	13072512	intron_variant	0	0.576619429209469	6e-06	5.22184874961636	(IGP23)	0.1484	[0.084-0.212] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p11.23	20	20653462	NR	RALGAPA2			ENSG00000188559	NA	NA	rs6132333-C	rs6132333	0	6132333	intron_variant	0	0.0251507142920947	1e-06	6	(IGP23)	0.5267	[0.31-0.74] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q24.1	10	97148976	NR	SLIT1			ENSG00000187122	NA	NA	rs7072055-C	rs7072055	0	7072055	intron_variant	0	0.831620998660116	2e-06	5.69897000433602	(IGP23)	0.2045	[0.12-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.1	11	19030325	NR	MRGPRX9P			ENSG00000255424	NA	NA	rs7111562-C	rs7111562	0	7111562	non_coding_transcript_exon_variant	0	0.140150397945511	4e-07	6.39794000867204	(IGP23)	0.2417	[0.15-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31218249	NR	HCG27 - AL662844.1	ENSG00000220890	ENSG00000255726		14281	4664	rs9263963-T	rs9263963	0	9263963	regulatory_region_variant	1	0.113293342563644	1e-06	6	(IGP23)	0.2567	[0.15-0.36] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p14.1	7	39081900	NR	POU6F2			ENSG00000106536	NA	NA	rs10464366-T	rs10464366	0	10464366	intron_variant	0	0.23005360311804	3e-06	5.52287874528034	(IGP24)	0.1748	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2011-04-11	21423719	Speliotes EK	2011-03-10	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21423719	Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.	Nonalcoholic fatty liver disease	880 Amish individuals, 6,296 European ancestry individuals	592 European ancestry cases, 1,405 European ancestry controls	22q13.31	22	43928847	PNPLA3	PNPLA3			ENSG00000100344	NA	NA	rs738409-G	rs738409	0	738409	missense_variant	0	0.23	4e-34	33.397940008672	(GOLD)	0.26	[0.22-0.30] unit increase	Affymetrix, Illumina [~ 2400000] (imputed)	N
2008-07-11	18594024	Sarasquete ME	2008-07-01	Blood	www.ncbi.nlm.nih.gov/pubmed/18594024	Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis.	Osteonecrosis of the jaw	22 European ancestry cases, 65 European ancestry controls	NA	10q23.33	10	95038791	CYP2C8	CYP2C8			ENSG00000138115	NA	NA	rs1934951-T	rs1934951	0	1934951	intron_variant	0	0.12	1e-06	6		12.75	[3.7-43.5]	Affymetrix [339972]	N
2008-11-12	18849993	Stacey SN	2008-10-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18849993	Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits.	Basal cell carcinoma	930 European ancestry cases, 33,117 European ancestry controls	1,216 European ancestry cases, 2,844 European ancestry controls	1p36.13	1	17395867	RCC2, ARHGEF10L, PADI4, PADI6	PADI6, PADI6			ENSG00000280949, ENSG00000276747	NA	NA	rs7538876-A	rs7538876	0	7538876	intron_variant	0	0.35	4e-12	11.397940008672		1.28	[1.19-1.37]	Illumina [304083]	N
2008-11-12	18849993	Stacey SN	2008-10-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18849993	Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits.	Basal cell carcinoma	930 European ancestry cases, 33,117 European ancestry controls	1,216 European ancestry cases, 2,844 European ancestry controls	1q42.13	1	228862088	RHOU	AL078624.1 - LINC02815	ENSG00000271399	ENSG00000282111		3532	160685	rs801114-G	rs801114	0	801114	intergenic_variant	1	0.33	6e-12	11.2218487496164		1.28	[1.19-1.37]	Illumina [304083]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q14.3	13	51150528	NR	C13orf42			ENSG00000226792	NA	NA	rs7325564-C	rs7325564	0	7325564	intron_variant	0	0.748729805345211	5e-06	5.30102999566398	(IGP9)	0.2463	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299056983073497	3e-09	8.52287874528034	(IGP9)	0.2011	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q15	12	70895776	NR	PTPRR			ENSG00000153233	NA	NA	rs4760854-G	rs4760854	0	4760854	intron_variant	0	0.270106625167935	9e-06	5.04575749056067	(IGP11)	0.1574	[0.088-0.227] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p23.2	8	2962287	NR	CSMD1			ENSG00000183117	NA	NA	rs4875857-C	rs4875857	0	4875857	intron_variant	0	0.177865535602329	5e-06	5.30102999566398	(IGP11)	0.1846	[0.11-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	113009359	NR	AC018464.1 - AC073346.2	ENSG00000234520	ENSG00000279288		13682	65765	rs6969802-G	rs6969802	0	6969802	intergenic_variant	1	0.0792205338110166	5e-06	5.30102999566398	(IGP11)	0.2608	[0.15-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q21.31	13	62356167	NR	LINC00459 - AL356102.1	ENSG00000229307	ENSG00000276586		27334	41478	rs9563960-G	rs9563960	0	9563960	intergenic_variant	1	0.296353501567398	7e-06	5.15490195998574	(IGP11)	0.1546	[0.087-0.222] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q24.1	10	95541247	NR	SORBS1			ENSG00000095637	NA	NA	rs11188352-G	rs11188352	0	11188352	intron_variant	0	0.042712513900135	6e-06	5.22184874961636	(IGP12)	0.4192	[0.24-0.6] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699626190283401	5e-06	5.30102999566398	(IGP12)	0.1589	[0.09-0.227] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187014891	NR	ST6GAL1			ENSG00000073849	NA	NA	rs17776120-C	rs17776120	0	17776120	intron_variant	0	0.637453049482681	2e-06	5.69897000433602	(IGP12)	0.1649	[0.097-0.233] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q25.1	15	79721080	NR	AC023968.1 - AC026826.3	ENSG00000259208	ENSG00000260674		52264	22231	rs2692194-G	rs2692194	0	2692194	intergenic_variant	1	0.626112833558255	9e-06	5.04575749056067	(IGP12)	0.1502	[0.084-0.217] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p21.3	7	11251773	NR	AC004160.1			ENSG00000230333	NA	NA	rs4720952-G	rs4720952	0	4720952	intron_variant	0	0.419193108861898	3e-07	6.52287874528034	(IGP12)	0.1583	[0.098-0.219] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p13	20	4406487	NR	ADRA1D - AL139350.1	ENSG00000171873	ENSG00000236387		157200	15699	rs586446-C	rs586446	0	586446	regulatory_region_variant	1	0.118161679262258	2e-06	5.69897000433602	(IGP12)	0.2296	[0.13-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q24.3	6	147438398	NR	YAP1P1 - SAMD5	ENSG00000220494	ENSG00000203727		30117	70292	rs9403856-C	rs9403856	0	9403856	intergenic_variant	1	0.86167473954116	4e-07	6.39794000867204	(IGP12)	0.3492	[0.21-0.48] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q31.1	13	78807966	NR	LINC00331			ENSG00000225427	NA	NA	rs9574309-C	rs9574309	0	9574309	intron_variant	0	0.432876341880342	2e-06	5.69897000433602	(IGP12)	0.1596	[0.093-0.226] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33153529	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813957-G	rs10813957	0	10813957	intron_variant	0	0.738414638629283	5e-08	7.30102999566398	(IGP13)	0.196	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836731980863373	1e-10	10	(IGP13)	0.2875	[0.2-0.38] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p22.3	1	86585518	NR	CLCA4-AS1			ENSG00000236915	NA	NA	rs1953652-C	rs1953652	0	1953652	intron_variant	0	0.653295152202937	5e-06	5.30102999566398	(IGP13)	0.147	[0.084-0.21] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187014937	NR	ST6GAL1			ENSG00000073849	NA	NA	rs3821819-G	rs3821819	0	3821819	intron_variant	0	0.632029343569203	3e-06	5.52287874528034	(IGP13)	0.1633	[0.095-0.231] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p13.3	9	36099402	RECK	RECK			ENSG00000122707	NA	NA	rs4878639-C	rs4878639	0	4878639	intron_variant	0	0.263725273253227	6e-06	5.22184874961636	(IGP13)	0.1615	[0.092-0.231] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q13.1	8	65711997	NR	MTFR1			ENSG00000066855	NA	NA	rs10504390-G	rs10504390	0	10504390	intron_variant	0	0.0804795064530485	1e-07	7	(IGP14)	0.2953	[0.19-0.4] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698919993324432	9e-07	6.04575749056067	(IGP14)	0.1715	[0.1-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q14.3	2	124499159	NR	CNTNAP5			ENSG00000155052	NA	NA	rs11899928-C	rs11899928	0	11899928	intron_variant	0	0.0215231680017802	9e-06	5.04575749056067	(IGP14)	0.685	[0.38-0.99] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q12.1	8	58596021	NR	NSMAF			ENSG00000035681	NA	NA	rs11994937-C	rs11994937	0	11994937	intron_variant	0	0.978061912475822	5e-06	5.30102999566398	(IGP14)	0.5011	[0.29-0.72] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	3e-08	7.52287874528034	(IGP14)	0.2294	[0.15-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q22.1	8	93210716	NR	C8orf87 - LINC00535	ENSG00000279847	ENSG00000246662		43866	2586	rs278541-C	rs278541	0	278541	intergenic_variant	1	0.97906300623053	4e-08	7.39794000867204	(IGP14)	0.8017	[0.52-1.09] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q23.3	16	81927353	NR	PLCG2			ENSG00000197943	NA	NA	rs3813009-C	rs3813009	0	3813009	intron_variant	0	0.223729928793947	4e-07	6.39794000867204	(IGP8)	0.2122	[0.13-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p24.3	3	20916318	NR	SGO1-AS1			ENSG00000231304	NA	NA	rs6787231-C	rs6787231	0	6787231	intron_variant	0	0.900662045838896	5e-06	5.30102999566398	(IGP8)	0.261	[0.15-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p11.22	12	28040056	NR	PTHLH - CCDC91	ENSG00000087494	ENSG00000123106		67323	93193	rs7964407-G	rs7964407	0	7964407	intergenic_variant	1	0.620613410769915	6e-06	5.22184874961636	(IGP8)	0.2061	[0.12-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.3	12	103640541	NR	STAB2			ENSG00000136011	NA	NA	rs1650123-C	rs1650123	0	1650123	intron_variant	0	0.577816124610592	6e-06	5.22184874961636	(IGP8)	0.1516	[0.086-0.218] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p25.1	2	9119469	NR	AC093904.3 - AC093904.1	ENSG00000244310	ENSG00000240980		2522	23697	rs9636252-C	rs9636252	0	9636252	intergenic_variant	1	0.641289432131731	3e-06	5.52287874528034	(IGP8)	0.1514	[0.087-0.215] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31834688	NR	SNHG32, SNHG32, SNHG32, SNHG32, AL671762.1			ENSG00000226710, ENSG00000234728, ENSG00000204387, ENSG00000229300, ENSG00000285565	NA	NA	rs4711279-C	rs4711279	0	4711279	5_prime_UTR_variant	0	0.824401248864668	4e-06	5.39794000867204	(IGP1)	0.1774	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q13.2	11	68164294	SUV420H1	KMT5B			ENSG00000110066	NA	NA	rs4930561-G	rs4930561	0	4930561	intron_variant	0	0.510670339237057	1e-08	8	(IGP1)	0.1714	[0.11-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17p11.2	17	17057664	NR	MPRIP			ENSG00000133030	NA	NA	rs6502557-G	rs6502557	0	6502557	missense_variant	0	0.861939099364214	6e-06	5.22184874961636	(IGP1)	0.2172	[0.12-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q22.3	18	75185206	NR	AC015819.5 - ZADH2	ENSG00000285915	ENSG00000180011		59641	9907	rs9948784-G	rs9948784	0	9948784	regulatory_region_variant	1	0.9873089	1e-06	6	(IGP1)	1.8106	[1.08-2.54] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q41	1	215883006	NR	USH2A			ENSG00000042781	NA	NA	rs17025548-G	rs17025548	0	17025548	intron_variant	0	0.165189309375	8e-06	5.09691001300806	(IGP10)	0.1954	[0.11-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q31.2	1	191970658	NR	LINC02770			ENSG00000228215	NA	NA	rs17403780-T	rs17403780	0	17403780	intron_variant	0	0.910622742901786	1e-06	6	(IGP10)	0.3351	[0.2-0.47] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17844499	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		108628	42864	rs2077147-C	rs2077147	0	2077147	intergenic_variant	1	0.336549315178571	3e-06	5.52287874528034	(IGP10)	0.1568	[0.091-0.223] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189377544642857	9e-10	9.04575749056067	(IGP10)	0.2557	[0.17-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q21.2	9	77705449	NR	GNA14 - GNAQ	ENSG00000156049	ENSG00000156052		57127	10648	rs4745661-G	rs4745661	0	4745661	intergenic_variant	1	0.684846625	3e-06	5.52287874528034	(IGP10)	0.1618	[0.094-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p11.22	10	33116159	NR	IATPR			ENSG00000233387	NA	NA	rs7902627-C	rs7902627	0	7902627	intron_variant	0	0.135378764285714	8e-06	5.09691001300806	(IGP10)	0.1989	[0.11-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.3	12	105058664	NR	ALDH1L2, C12orf45			ENSG00000136010, ENSG00000151131	NA	NA	rs10861337-G	rs10861337	0	10861337	intron_variant	0	0.900366844872369	2e-07	6.69897000433602	(IGP11)	0.2653	[0.16-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	47757912	NR	TBX21 - OSBPL7	ENSG00000073861	ENSG00000006025		11790	49460	rs11651000-G	rs11651000	0	11651000	regulatory_region_variant	1	0.840287136139722	8e-06	5.09691001300806	(IGP11)	0.1911	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q42.12	1	225402973	NR	LBR			ENSG00000143815	NA	NA	rs16844841-C	rs16844841	0	16844841	3_prime_UTR_variant	0	0.0583146565158979	4e-06	5.39794000867204	(IGP11)	0.3163	[0.18-0.45] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q21.3	14	47584956	NR	MDGA2			ENSG00000139915	NA	NA	rs4143912-G	rs4143912	0	4143912	intron_variant	0	0.417046732532265	7e-06	5.15490195998574	(IGP45)	0.1425	[0.08-0.205] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p13	20	569274	NR	CSNK2A1 - TCF15	ENSG00000101266	ENSG00000125878		25439	34523	rs6084946-C	rs6084946	0	6084946	regulatory_region_variant	1	0.233844371161549	5e-06	5.30102999566398	(IGP45)	0.2176	[0.12-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.2	10	61935289	NR	ARID5B			ENSG00000150347	NA	NA	rs6479779-C	rs6479779	0	6479779	intron_variant	0	0.345248463284379	1e-06	6	(IGP45)	0.1943	[0.12-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50306538	NR	IKZF1			ENSG00000185811	NA	NA	rs7781977-C	rs7781977	0	7781977	intron_variant	0	0.695324747663551	5e-07	6.30102999566398	(IGP45)	0.1658	[0.1-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.31	22	43808439	NR	EFCAB6			ENSG00000186976	NA	NA	rs8140172-C	rs8140172	0	8140172	intron_variant	0	0.985708288681948	6e-06	5.22184874961636	(IGP45)	0.8795	[0.5-1.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	3e-13	12.5228787452803	(IGP45)	0.2468	[0.18-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q21.13	7	89065756	NR	ZNF804B			ENSG00000182348	NA	NA	rs10236237-T	rs10236237	0	10236237	intron_variant	0	0.267777818671454	5e-06	5.30102999566398	(IGP46)	0.1613	[0.092-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q22	17	58236543	NR	LPO			ENSG00000167419	NA	NA	rs8067912-C	rs8067912	0	8067912	intron_variant	0	0.0305423055728934	1e-06	6	(IGP35)	0.4386	[0.26-0.62] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q23.2	11	114519384	NR	AC020549.3 - NXPE1	ENSG00000270204	ENSG00000095110		1013	2261	rs9326244-C	rs9326244	0	9326244	intergenic_variant	1	0.878929753455194	5e-07	6.30102999566398	(IGP35)	0.237	[0.14-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p12.2	10	23014324	NR	ARMC3, AL139815.1			ENSG00000165309, ENSG00000286924	NA	NA	rs1054052-T	rs1054052	0	1054052	3_prime_UTR_variant	0	0.285274903125	6e-07	6.22184874961636	(IGP36)	0.1727	[0.1-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q21.12	7	86719683	NR	GRM3			ENSG00000198822	NA	NA	rs2189812-C	rs2189812	0	2189812	intron_variant	0	0.258550537841469	6e-06	5.22184874961636	(IGP11)	0.1624	[0.092-0.233] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p24.1	2	23369274	NR	AC012506.2 - AC012506.4	ENSG00000223634	ENSG00000235497		8898	5955	rs2577704-G	rs2577704	0	2577704	intergenic_variant	1	0.900847768293775	3e-06	5.52287874528034	(IGP11)	0.2408	[0.14-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q25	11	134703916	NR	AP001999.2 - LINC02706	ENSG00000285640	ENSG00000255344		1912	8623	rs11825685-C	rs11825685	0	11825685	intergenic_variant	1	0.889723712633929	9e-06	5.04575749056067	(IGP36)	0.227	[0.13-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33124874	B4GALT1	B4GALT1			ENSG00000086062	NA	NA	rs12342831-C	rs12342831	0	12342831	intron_variant	0	0.2625544125	1e-10	10	(IGP36)	0.2299	[0.16-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q24.1	10	95535832	NR	SORBS1			ENSG00000095637	NA	NA	rs12772243-G	rs12772243	0	12772243	intron_variant	0	0.0871224178571429	5e-06	5.30102999566398	(IGP36)	0.2472	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q31.1	5	135828929	NR	SLC25A48			ENSG00000145832	NA	NA	rs13178541-C	rs13178541	0	13178541	intron_variant	0	0.811571763392857	5e-06	5.30102999566398	(IGP36)	0.1833	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q22	17	56046612	NR	ANKFN1			ENSG00000153930	NA	NA	rs2060070-G	rs2060070	0	2060070	intron_variant	0	0.76230421875	9e-07	6.04575749056067	(IGP36)	0.1789	[0.11-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q24.2	11	127240288	NR	AP003121.1 - LINC02712	ENSG00000272642	ENSG00000273409		16839	30741	rs2514895-C	rs2514895	0	2514895	intergenic_variant	1	0.812138921875	2e-06	5.69897000433602	(IGP36)	0.1858	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q12	6	65468587	NR	EYS			ENSG00000188107	NA	NA	rs4710520-C	rs4710520	0	4710520	intron_variant	0	0.00803558	6e-06	5.22184874961636	(IGP36)	2.107	[1.2-3.02] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39445695	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268		8635	11317	rs5757676-C	rs5757676	0	5757676	intergenic_variant	1	0.775682419642857	1e-07	7	(IGP36)	0.1968	[0.12-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p11.2	2	84217762	NR	ST6GALNAC2P1 - FUNDC2P2	ENSG00000228902	ENSG00000182814		177042	72921	rs6547537-G	rs6547537	0	6547537	regulatory_region_variant	1	0.784824532589286	4e-06	5.39794000867204	(IGP36)	0.1881	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p12.2	10	23014324	NR	ARMC3, AL139815.1			ENSG00000165309, ENSG00000286924	NA	NA	rs1054052-T	rs1054052	0	1054052	3_prime_UTR_variant	0	0.285370675591254	3e-06	5.52287874528034	(IGP37)	0.1625	[0.094-0.231] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13321046	NR	SEPHS1			ENSG00000086475	NA	NA	rs10508459-T	rs10508459	0	10508459	intron_variant	0	0.47438586013363	2e-06	5.69897000433602	(IGP9)	0.1446	[0.085-0.204] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q25	4	109976429	NR	EGF			ENSG00000138798	NA	NA	rs11568995-G	rs11568995	0	11568995	intron_variant	0	0.9884981	5e-06	5.30102999566398	(IGP9)	1.6228	[0.93-2.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q33.3	5	157983270	NR	RNU2-48P - MARK2P11	ENSG00000222626	ENSG00000253743		6314	1388	rs11958404-T	rs11958404	0	11958404	intergenic_variant	1	0.113988281514477	1e-06	6	(IGP9)	0.2522	[0.15-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p14	4	37645612	NR	RELL1			ENSG00000181826	NA	NA	rs13144232-G	rs13144232	0	13144232	intron_variant	0	0.63805114610245	6e-07	6.22184874961636	(IGP9)	0.1638	[0.1-0.228] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189660889532294	3e-13	12.5228787452803	(IGP9)	0.304	[0.22-0.39] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p21.1	7	16797830	NR	AGR2			ENSG00000106541	NA	NA	rs2280655-C	rs2280655	0	2280655	intron_variant	0	0.977065699331849	4e-06	5.39794000867204	(IGP9)	0.6294	[0.36-0.9] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.639296878396437	9e-07	6.04575749056067	(IGP9)	0.1593	[0.096-0.223] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p11.2	2	88089019	NR	SMYD1			ENSG00000115593	NA	NA	rs2919856-T	rs2919856	0	2919856	intron_variant	0	0.545002280178174	2e-06	5.69897000433602	(IGP9)	0.1475	[0.087-0.208] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.31	22	44165407	NR	PARVB			ENSG00000188677	NA	NA	rs5764106-C	rs5764106	0	5764106	intron_variant	0	0.229970760801782	5e-06	5.30102999566398	(IGP9)	0.1865	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	49213433	NR	ABI3			ENSG00000108798	NA	NA	rs627386-G	rs627386	0	627386	intron_variant	0	0.974019461024499	4e-06	5.39794000867204	(IGP9)	0.5473	[0.32-0.78] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	47757912	NR	TBX21 - OSBPL7	ENSG00000073861	ENSG00000006025		11790	49460	rs11651000-G	rs11651000	0	11651000	regulatory_region_variant	1	0.83992863016158	9e-06	5.04575749056067	(IGP46)	0.1897	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	NR	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.393307344254937	2e-13	12.698970004336	(IGP46)	0.2328	[0.17-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q26	4	116928293	NR	AC093765.3			ENSG00000287290	NA	NA	rs2389339-G	rs2389339	0	2389339	intron_variant	0	0.790110045780969	2e-06	5.69897000433602	(IGP46)	0.1846	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.637533007630161	4e-08	7.39794000867204	(IGP46)	0.1744	[0.11-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698919993324432	5e-06	5.30102999566398	(IGP47)	0.1609	[0.092-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q13.31	3	113711752	NR	USF3 - NAA50	ENSG00000176542	ENSG00000121579		15106	4706	rs11711311-G	rs11711311	0	11711311	intergenic_variant	1	0.396079672452158	4e-07	6.39794000867204	(IGP47)	0.1632	[0.1-0.227] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q36.3	2	229485273	NR	DNER			ENSG00000187957	NA	NA	rs11890081-C	rs11890081	0	11890081	intron_variant	0	0.0172129438807299	8e-06	5.09691001300806	(IGP47)	0.6811	[0.38-0.98] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q13.3	8	70632513	NR	LACTB2-AS1			ENSG00000246366	NA	NA	rs13272623-G	rs13272623	0	13272623	non_coding_transcript_exon_variant	0	0.154915348909657	2e-06	5.69897000433602	(IGP47)	0.218	[0.13-0.31] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q13.11	3	103794592	NR	TUBBP11 - RAP1BP2	ENSG00000243195	ENSG00000214405		163680	268447	rs1673866-C	rs1673866	0	1673866	intergenic_variant	1	0.63878196306186	7e-06	5.15490195998574	(IGP47)	0.1439	[0.081-0.206] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.1	10	51502873	NR	PRKG1			ENSG00000185532	NA	NA	rs1952138-C	rs1952138	0	1952138	intron_variant	0	0.766987149087672	3e-06	5.52287874528034	(IGP47)	0.1724	[0.1-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q31.1	2	176147850	NR	HOXD3			ENSG00000128652	NA	NA	rs4972806-C	rs4972806	0	4972806	intron_variant	0	0.635161429906542	8e-06	5.09691001300806	(IGP47)	0.1425	[0.08-0.205] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.3	12	103640541	NR	STAB2			ENSG00000136011	NA	NA	rs1650123-C	rs1650123	0	1650123	intron_variant	0	0.577816124610592	1e-06	6	(IGP48)	0.1628	[0.097-0.229] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.1	3	150979421	NR	AC020636.1, CLRN1-AS1			ENSG00000243273, ENSG00000239265	NA	NA	rs16863118-C	rs16863118	0	16863118	intron_variant	0	0.836539205162439	7e-07	6.15490195998574	(IGP48)	0.2044	[0.12-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p16.1	2	55746597	NR	PNPT1 - EFEMP1	ENSG00000138035	ENSG00000115380		52734	119370	rs2163237-C	rs2163237	0	2163237	intergenic_variant	1	0.671727695594125	5e-06	5.30102999566398	(IGP48)	0.1519	[0.087-0.217] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p22.1	7	5840746	NR	ZNF815P			ENSG00000235944	NA	NA	rs308097-G	rs308097	0	308097	non_coding_transcript_exon_variant	0	0.966564075211393	2e-06	5.69897000433602	(IGP48)	0.4299	[0.25-0.61] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q23.3	16	81927353	NR	PLCG2			ENSG00000197943	NA	NA	rs3813009-C	rs3813009	0	3813009	intron_variant	0	0.223729928793947	4e-06	5.39794000867204	(IGP48)	0.1929	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p24.3	3	20916318	NR	SGO1-AS1			ENSG00000231304	NA	NA	rs6787231-C	rs6787231	0	6787231	intron_variant	0	0.900662045838896	5e-06	5.30102999566398	(IGP48)	0.2602	[0.15-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16p12.3	16	17968279	NR	AC010601.1			ENSG00000259929	NA	NA	rs7194356-C	rs7194356	0	7194356	intron_variant	0	0.895432401869159	7e-06	5.15490195998574	(IGP48)	0.2261	[0.13-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q23.1	6	130565292	NR	TMEM200A - Y_RNA	ENSG00000164484	ENSG00000265852		122229	8704	rs9492645-G	rs9492645	0	9492645	intergenic_variant	1	0.947434826924789	7e-06	5.15490195998574	(IGP48)	0.3293	[0.19-0.47] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13313131	NR	RBISP1 - SEPHS1	ENSG00000226209	ENSG00000086475		4684	4297	rs1095368-C	rs1095368	0	1095368	intergenic_variant	1	0.437467493541203	7e-07	6.15490195998574	(IGP49)	0.1528	[0.092-0.213] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q25	4	109976429	NR	EGF			ENSG00000138798	NA	NA	rs11568995-G	rs11568995	0	11568995	intron_variant	0	0.9884981	4e-07	6.39794000867204	(IGP49)	1.802	[1.11-2.5] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q33.3	5	157983270	NR	RNU2-48P - MARK2P11	ENSG00000222626	ENSG00000253743		6314	1388	rs11958404-T	rs11958404	0	11958404	intergenic_variant	1	0.113988281514477	8e-06	5.09691001300806	(IGP49)	0.231	[0.13-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q43	1	239233804	NR	AC093426.2 - AC093426.1	ENSG00000287589	ENSG00000259776		21520	14004	rs1339738-C	rs1339738	0	1339738	regulatory_region_variant	1	0.0857549797772829	7e-06	5.15490195998574	(IGP49)	0.2911	[0.16-0.42] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189660889532294	7e-16	15.1549019599857	(IGP49)	0.3363	[0.25-0.42] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p14	4	37643767	NR	RELL1			ENSG00000181826	NA	NA	rs4832928-C	rs4832928	0	4832928	intron_variant	0	0.701397954120267	2e-06	5.69897000433602	(IGP49)	0.1627	[0.096-0.229] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q35.1	4	182379461	NR	TENM3			ENSG00000218336	NA	NA	rs4862046-G	rs4862046	0	4862046	intron_variant	0	0.907610376436526	6e-07	6.22184874961636	(IGP49)	0.2767	[0.17-0.39] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.31	22	44165407	NR	PARVB			ENSG00000188677	NA	NA	rs5764106-C	rs5764106	0	5764106	intron_variant	0	0.229970760801782	2e-06	5.69897000433602	(IGP49)	0.1956	[0.12-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299056983073497	3e-09	8.52287874528034	(IGP49)	0.2003	[0.13-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	21q22.13	21	37445510	NR	DYRK1A			ENSG00000157540	NA	NA	rs11700462-G	rs11700462	0	11700462	intron_variant	0	0.89698245367811	5e-06	5.30102999566398	(IGP33)	0.2827	[0.16-0.4] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q24.33	12	129162056	NR	TMEM132D			ENSG00000151952	NA	NA	rs12580533-C	rs12580533	0	12580533	intron_variant	0	0.014010396137832	8e-06	5.09691001300806	(IGP33)	0.8247	[0.46-1.19] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q11.23	20	38349567	NR	LBP			ENSG00000129988	NA	NA	rs1739654-G	rs1739654	0	1739654	synonymous_variant	0	0.958833931431119	5e-06	5.30102999566398	(IGP33)	0.4461	[0.26-0.64] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q26.3	15	99817230	NR	AC090825.1			ENSG00000259363	NA	NA	rs1823874-C	rs1823874	0	1823874	non_coding_transcript_exon_variant	0	0.428499305840392	3e-06	5.52287874528034	(IGP33)	0.1478	[0.086-0.209] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.33	14	104883051	NR	CEP170B			ENSG00000099814	NA	NA	rs2028414-C	rs2028414	0	2028414	synonymous_variant	0	0.635674106107891	8e-06	5.09691001300806	(IGP33)	0.1399	[0.079-0.201] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p12.2	10	23014324	NR	ARMC3, AL139815.1			ENSG00000165309, ENSG00000286924	NA	NA	rs1054052-T	rs1054052	0	1054052	3_prime_UTR_variant	0	0.28422493357111	6e-06	5.22184874961636	(IGP33)	0.1566	[0.089-0.224] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.3	10	63107152	NR	EGR2 - RNU6-543P	ENSG00000122877	ENSG00000199446		187252	2987	rs10995439-G	rs10995439	0	10995439	regulatory_region_variant	1	0.500403761034329	1e-07	7	(IGP33)	0.1635	[0.1-0.22] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p11.23	20	20653462	NR	RALGAPA2			ENSG00000188559	NA	NA	rs6132333-C	rs6132333	0	6132333	intron_variant	0	0.0251061037895675	7e-07	6.15490195998574	(IGP33)	0.5397	[0.33-0.75] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.3	10	63107152	NR	EGR2 - RNU6-543P	ENSG00000122877	ENSG00000199446		187252	2987	rs10995439-G	rs10995439	0	10995439	regulatory_region_variant	1	0.500403761034329	3e-06	5.52287874528034	(IGP34)	0.1441	[0.084-0.205] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	28181087	NR	LINGO2			ENSG00000174482	NA	NA	rs1319535-C	rs1319535	0	1319535	intron_variant	0	0.345300509585377	9e-06	5.04575749056067	(IGP34)	0.1458	[0.081-0.21] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p21.3	7	12179909	NR	THSD7A - TMEM106B	ENSG00000005108	ENSG00000106460		347711	31361	rs17594709-G	rs17594709	0	17594709	intergenic_variant	1	0.283855287561302	5e-06	5.30102999566398	(IGP34)	0.1572	[0.09-0.225] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	51877490	NR	AC022433.1 - RNA5SP182	ENSG00000288035	ENSG00000251873		212442	9198	rs17835853-G	rs17835853	0	17835853	intergenic_variant	1	0.956751274008025	6e-06	5.22184874961636	(IGP34)	0.4694	[0.27-0.67] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q12	20	40849893	NR	AL035665.2 - RNA5SP484	ENSG00000286972	ENSG00000238908		91257	4226	rs6102185-G	rs6102185	0	6102185	intergenic_variant	1	0.422547655372269	5e-06	5.30102999566398	(IGP34)	0.1429	[0.082-0.204] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p11.23	20	20653462	NR	RALGAPA2			ENSG00000188559	NA	NA	rs6132333-C	rs6132333	0	6132333	intron_variant	0	0.0251061037895675	8e-06	5.09691001300806	(IGP34)	0.4924	[0.28-0.71] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q23.3	8	115318626	NR	CARSP2 - TRPS1	ENSG00000253756	ENSG00000104447		526697	89870	rs6983039-G	rs6983039	0	6983039	intergenic_variant	1	0.971469000267499	9e-06	5.04575749056067	(IGP34)	0.4445	[0.25-0.64] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.298878222915738	2e-10	9.69897000433602	(IGP34)	0.2136	[0.15-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q12	12	38859306	NR	CPNE8			ENSG00000139117	NA	NA	rs11169838-C	rs11169838	0	11169838	intron_variant	0	0.680712065091395	8e-06	5.09691001300806	(IGP35)	0.1671	[0.094-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699243829246545	5e-44	43.301029995664	(IGP35)	0.4893	[0.42-0.56] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.23	8	136837768	NR	LINC02055			ENSG00000254101	NA	NA	rs16906415-G	rs16906415	0	16906415	intron_variant	0	0.107695718234507	3e-06	5.52287874528034	(IGP35)	0.235	[0.14-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	81194468	NR	CEP131			ENSG00000141577	NA	NA	rs2279913-C	rs2279913	0	2279913	intron_variant	0	0.439263302273741	4e-07	6.39794000867204	(IGP35)	0.1579	[0.097-0.219] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p13.2	12	11809639	NR	ETV6			ENSG00000139083	NA	NA	rs7314811-C	rs7314811	0	7314811	intron_variant	0	0.35010278555506	4e-06	5.39794000867204	(IGP35)	0.1452	[0.083-0.207] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176986749442711	7e-17	16.1549019599857	(IGP35)	0.3659	[0.28-0.45] unit decrease	Illumina [~ 2500000] (imputed)	N
2009-09-28	17998437	Li H	2007-11-12	Arch Neurol	www.ncbi.nlm.nih.gov/pubmed/17998437	Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.	Alzheimer's disease	753 European ancestry cases, 736 European ancestry controls	418 European ancestry cases, 249 European ancestry controls	19q13.32	19	44919689	APOE, APOC1	APOC1 - APOC1P1	ENSG00000130208	ENSG00000214855		340	7115	rs4420638-?	rs4420638	0	4420638	regulatory_region_variant	1	NR	2e-44	43.698970004336		NA		Affymetrix [469438]	N
2012-01-19	22197933	Hu Z	2011-12-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22197933	A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.	Non-obstructive azoospermia	981 Han Chinese ancestry cases, 1,657 Han Chinese ancestry controls	1,946 Han Chinese ancestry cases, 4,077 Han Chinese ancestry controls	1p13.3	1	106793679	PRMT6	AL596327.1 - MTATP6P14	ENSG00000270976	ENSG00000233449		13244	9076	rs12097821-?	rs12097821	0	12097821	regulatory_region_variant	1	NR	6e-10	9.22184874961636		1.25	[1.17-1.34]	Affymetrix [587347]	N
2012-01-19	22197933	Hu Z	2011-12-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22197933	A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.	Non-obstructive azoospermia	981 Han Chinese ancestry cases, 1,657 Han Chinese ancestry controls	1,946 Han Chinese ancestry cases, 4,077 Han Chinese ancestry controls	1p36.32	1	2461209	MMEL1, PEX10	PLCH2, PLCH2			ENSG00000276429, ENSG00000149527	NA	NA	rs2477686-?	rs2477686	0	2477686	intron_variant	0	NR	6e-12	11.2218487496164		1.39	[1.26-1.52]	Affymetrix [587347]	N
2012-01-19	22197933	Hu Z	2011-12-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22197933	A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.	Non-obstructive azoospermia	981 Han Chinese ancestry cases, 1,657 Han Chinese ancestry controls	1,946 Han Chinese ancestry cases, 4,077 Han Chinese ancestry controls	12p12.1	12	24031610	SOX5	SOX5			ENSG00000134532	NA	NA	rs10842262-?	rs10842262	0	10842262	intron_variant	0	NR	2e-09	8.69897000433602		1.23	[1.15-1.32]	Affymetrix [587347]	N
2012-01-19	22197933	Hu Z	2011-12-25	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/22197933	A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia.	Non-obstructive azoospermia	981 Han Chinese ancestry cases, 1,657 Han Chinese ancestry controls	1,946 Han Chinese ancestry cases, 4,077 Han Chinese ancestry controls	20p13	20	1778944	LOC100289473	AL109809.5, AL109809.1			ENSG00000286288, ENSG00000232528	NA	NA	rs6080550-?	rs6080550	0	6080550	intron_variant	0	NR	2e-09	8.69897000433602		1.27	[1.17-1.37]	Affymetrix [587347]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p16.1	2	59562570	NR	AC007100.1, AC007179.2			ENSG00000271955, ENSG00000233891	NA	NA	rs10203166-C	rs10203166	0	10203166	intron_variant	0	0.974135912544803	4e-06	5.39794000867204	(IGP5)	0.7988	[0.46-1.14] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p15.31	4	21204867	NR	KCNIP4			ENSG00000185774	NA	NA	rs1023721-T	rs1023721	0	1023721	intron_variant	0	0.941465292386465	1e-06	6	(IGP5)	0.3141	[0.19-0.44] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q36.1	7	151217985	ABCF2, SMARCD3	ABCF2, ABCF2			ENSG00000285292, ENSG00000033050	NA	NA	rs1122979-G	rs1122979	0	1122979	intron_variant	0	0.875342207034728	2e-09	8.69897000433602	(IGP5)	0.2945	[0.2-0.39] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q11.21	8	50472427	NR	SNTG1			ENSG00000147481	NA	NA	rs13272236-G	rs13272236	0	13272236	intron_variant	0	0.0365154950657895	2e-06	5.69897000433602	(IGP5)	0.7872	[0.46-1.11] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q22.32	9	96054202	NR	ERCC6L2			ENSG00000182150	NA	NA	rs1547201-C	rs1547201	0	1547201	intron_variant	0	0.530244325912734	4e-06	5.39794000867204	(IGP5)	0.1449	[0.083-0.206] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56028975	NR	AC008892.1			ENSG00000249236	NA	NA	rs16884711-C	rs16884711	0	16884711	intron_variant	0	0.189044272039181	2e-06	5.69897000433602	(IGP5)	0.1931	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q21.3	14	47584956	NR	MDGA2			ENSG00000139915	NA	NA	rs4143912-G	rs4143912	0	4143912	intron_variant	0	0.416787130454141	6e-06	5.22184874961636	(IGP5)	0.1434	[0.081-0.206] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368136455031166	7e-06	5.15490195998574	(IGP5)	0.1445	[0.081-0.208] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q21.2	10	61935289	NR	ARID5B			ENSG00000150347	NA	NA	rs6479779-C	rs6479779	0	6479779	intron_variant	0	0.345369661175423	2e-06	5.69897000433602	(IGP5)	0.1909	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.298923567230632	1e-10	10	(IGP5)	0.2178	[0.15-0.28] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5p15.1	5	16037993	NR	RNA5SP178 - MARCH11	ENSG00000222312	ENSG00000183654		4637	29146	rs1039443-C	rs1039443	0	1039443	intergenic_variant	1	0.105031482310793	8e-06	5.09691001300806	(IGP50)	0.2223	[0.12-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189640669950739	5e-10	9.30102999566398	(IGP50)	0.2588	[0.18-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q25.3	10	116065377	NR	GFRA1			ENSG00000151892	NA	NA	rs2302105-C	rs2302105	0	2302105	intron_variant	0	0.768104532915361	4e-06	5.39794000867204	(IGP50)	0.1688	[0.097-0.24] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.3	12	105065019	NR	C12orf45, ALDH1L2			ENSG00000151131, ENSG00000136010	NA	NA	rs10861342-C	rs10861342	0	10861342	intron_variant	0	0.099068749529359	2e-06	5.69897000433602	(IGP51)	0.2456	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q21.32	17	47757912	NR	TBX21 - OSBPL7	ENSG00000073861	ENSG00000006025		11790	49460	rs11651000-G	rs11651000	0	11651000	regulatory_region_variant	1	0.840144331241596	8e-06	5.09691001300806	(IGP51)	0.1906	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.392332365307037	2e-13	12.698970004336	(IGP51)	0.2323	[0.17-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p24.1	2	23369274	NR	AC012506.2 - AC012506.4	ENSG00000223634	ENSG00000235497		8898	5955	rs2577704-G	rs2577704	0	2577704	intergenic_variant	1	0.900979990049305	5e-06	5.30102999566398	(IGP51)	0.2366	[0.14-0.34] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	113009359	NR	AC018464.1 - AC073346.2	ENSG00000234520	ENSG00000279288		13682	65765	rs6969802-G	rs6969802	0	6969802	intergenic_variant	1	0.0788437633348274	3e-06	5.52287874528034	(IGP51)	0.2669	[0.16-0.38] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q26.1	15	93021742	NR	CHD2			ENSG00000173575	NA	NA	rs7179432-C	rs7179432	0	7179432	3_prime_UTR_variant	0	0.455903207978485	4e-06	5.39794000867204	(IGP51)	0.1569	[0.09-0.224] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q21.31	13	62356167	NR	LINC00459 - AL356102.1	ENSG00000229307	ENSG00000276586		27334	41478	rs9563960-G	rs9563960	0	9563960	intergenic_variant	1	0.296508162707306	4e-06	5.39794000867204	(IGP51)	0.1591	[0.092-0.226] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q13.3	11	69787644	NR	FGF4 - FGF3	ENSG00000075388	ENSG00000186895		12303	22324	rs10796849-C	rs10796849	0	10796849	intergenic_variant	1	0.111934	6e-06	5.22184874961636	(IGP52)	0.6111	[0.35-0.88] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q24.1	10	95541247	NR	SORBS1			ENSG00000095637	NA	NA	rs11188352-G	rs11188352	0	11188352	intron_variant	0	0.0425983854693141	5e-06	5.30102999566398	(IGP52)	0.4264	[0.24-0.61] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q31.1	13	78806681	NR	LINC00331			ENSG00000225427	NA	NA	rs2184180-G	rs2184180	0	2184180	intron_variant	0	0.362504259025271	5e-06	5.30102999566398	(IGP52)	0.1637	[0.093-0.234] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q36.2	7	153881331	NR	AC005998.1 - DPP6	ENSG00000287744	ENSG00000130226		132345	5766	rs38989-G	rs38989	0	38989	intergenic_variant	1	0.405296777978339	7e-06	5.15490195998574	(IGP52)	0.1524	[0.086-0.219] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p21.3	7	11251773	NR	AC004160.1			ENSG00000230333	NA	NA	rs4720952-G	rs4720952	0	4720952	intron_variant	0	0.419614749097473	7e-07	6.15490195998574	(IGP52)	0.1534	[0.093-0.214] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p16.1	4	6734638	NR	BLOC1S4 - AC106045.1	ENSG00000186222	ENSG00000287331		16974	28870	rs7661864-G	rs7661864	0	7661864	TF_binding_site_variant	1	0.699190685672515	5e-06	5.30102999566398	(IGP52)	0.3307	[0.19-0.47] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q24.3	6	147438398	NR	YAP1P1 - SAMD5	ENSG00000220494	ENSG00000203727		30117	70292	rs9403856-C	rs9403856	0	9403856	intergenic_variant	1	0.861277425090253	2e-06	5.69897000433602	(IGP52)	0.3292	[0.19-0.46] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33153529	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813957-G	rs10813957	0	10813957	intron_variant	0	0.738414638629283	2e-09	8.69897000433602	(IGP53)	0.2163	[0.15-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836731980863373	7e-11	10.1549019599857	(IGP53)	0.2916	[0.2-0.38] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p22.3	1	86585518	NR	CLCA4-AS1			ENSG00000236915	NA	NA	rs1953652-C	rs1953652	0	1953652	intron_variant	0	0.653295152202937	4e-06	5.39794000867204	(IGP53)	0.1488	[0.086-0.212] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p13.3	9	36099402	RECK	RECK			ENSG00000122707	NA	NA	rs4878639-C	rs4878639	0	4878639	intron_variant	0	0.263725273253227	6e-07	6.22184874961636	(IGP53)	0.1779	[0.11-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.122643248331108	4e-06	5.39794000867204	(IGP53)	0.2224	[0.13-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.3	12	108483764	NR	LINC01498			ENSG00000247213	NA	NA	rs918304-C	rs918304	0	918304	intron_variant	0	0.00963820126262628	8e-06	5.09691001300806	(IGP53)	1.5994	[0.9-2.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p22	8	14256307	NR	SGCZ			ENSG00000185053	NA	NA	rs9886428-G	rs9886428	0	9886428	intron_variant	0	0.455051607476636	5e-06	5.30102999566398	(IGP53)	0.1403	[0.08-0.201] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p15.3	7	23440848	NR	IGF2BP3			ENSG00000136231	NA	NA	rs11763760-C	rs11763760	0	11763760	intron_variant	0	0.797056939029818	2e-06	5.69897000433602	(IGP54)	0.1815	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698797577867024	8e-17	16.0969100130081	(IGP37)	0.2929	[0.22-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q22	17	56046612	NR	ANKFN1			ENSG00000153930	NA	NA	rs2060070-G	rs2060070	0	2060070	intron_variant	0	0.761979803659081	2e-06	5.69897000433602	(IGP37)	0.1745	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33139455	NR	B4GALT1			ENSG00000086062	NA	NA	rs3780486-C	rs3780486	0	3780486	intron_variant	0	0.737437251227131	9e-11	10.0457574905607	(IGP37)	0.2309	[0.16-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q12	6	65468587	NR	EYS			ENSG00000188107	NA	NA	rs4710520-C	rs4710520	0	4710520	intron_variant	0	0.00804562	3e-06	5.52287874528034	(IGP37)	2.1675	[1.26-3.08] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.1	1	79043424	NR	ADGRL4			ENSG00000162618	NA	NA	rs6687262-C	rs6687262	0	6687262	intron_variant	0	0.553310385988398	4e-07	6.39794000867204	(IGP37)	0.1576	[0.097-0.219] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176702207496653	5e-08	7.30102999566398	(IGP37)	0.2394	[0.15-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p12.2	10	23014324	NR	ARMC3, AL139815.1			ENSG00000165309, ENSG00000286924	NA	NA	rs1054052-T	rs1054052	0	1054052	3_prime_UTR_variant	0	0.285116272403032	2e-06	5.69897000433602	(IGP38)	0.1661	[0.098-0.234] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.698840198840838	5e-17	16.301029995664	(IGP38)	0.2948	[0.23-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q21.1	5	99380064	NR	LINC02062 - AC114324.2	ENSG00000248489	ENSG00000249444		385051	109495	rs11745890-C	rs11745890	0	11745890	intergenic_variant	1	0.0301678793134195	4e-06	5.39794000867204	(IGP38)	0.5502	[0.32-0.78] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q22	17	56046612	NR	ANKFN1			ENSG00000153930	NA	NA	rs2060070-G	rs2060070	0	2060070	intron_variant	0	0.761965887650468	2e-06	5.69897000433602	(IGP38)	0.1748	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33139455	NR	B4GALT1			ENSG00000086062	NA	NA	rs3780486-C	rs3780486	0	3780486	intron_variant	0	0.737450810521623	5e-11	10.301029995664	(IGP38)	0.2341	[0.16-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q12	6	65468587	NR	EYS			ENSG00000188107	NA	NA	rs4710520-C	rs4710520	0	4710520	intron_variant	0	0.00803558	5e-06	5.30102999566398	(IGP38)	2.1251	[1.21-3.04] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.1	1	79043424	NR	ADGRL4			ENSG00000162618	NA	NA	rs6687262-C	rs6687262	0	6687262	intron_variant	0	0.553040158270174	5e-07	6.30102999566398	(IGP38)	0.1567	[0.096-0.218] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176770524297815	5e-08	7.30102999566398	(IGP38)	0.2399	[0.15-0.33] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33128023	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813951-G	rs10813951	0	10813951	intron_variant	0	0.262554376171352	1e-09	9	(IGP39)	0.2169	[0.15-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	1p31.1	1	83788868	intergenic	LINC01725			ENSG00000233008	NA	NA	rs7552393-?	rs7552393	0	7552393	intron_variant	0	NR	5e-07	6.30102999566398	(TNFA)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	10q26.2	10	128135192	PTPRE, MKI67	MKI67 - LINC01163	ENSG00000148773	ENSG00000280953		8769	45840	rs2387326-?	rs2387326	0	2387326	intergenic_variant	1	NR	1e-06	6	(VitKPhylloq)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	11q23.2	11	113425897	DRD2	DRD2			ENSG00000149295	NA	NA	rs1079596-?	rs1079596	0	1079596	intron_variant	0	NR	3e-06	5.52287874528034	(ANP6)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	9q21.32	9	82800066	intergenic	AL162726.3 - RASEF	ENSG00000228430	ENSG00000165105		19872	179524	rs1998303-?	rs1998303	0	1998303	intergenic_variant	1	NR	1e-06	6	(ALT)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	4q31.1	4	140466284	CLGN, ELMOD2	MGAT4D			ENSG00000205301	NA	NA	rs17532515-?	rs17532515	1	1594468	intron_variant	0	NR	1e-06	6	(Bilirubin)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	1q23.2	1	159226975	IGSF4B	CADM3-AS1 - MPTX1	ENSG00000225670	ENSG00000215846		19002	49528	rs10489849-?	rs10489849	0	10489849	regulatory_region_variant	1	NR	1e-06	6	(MCP1)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	15q21.3	15	54388434	intergenic	UNC13C			ENSG00000137766	NA	NA	rs10518765-?	rs10518765	0	10518765	intron_variant	0	NR	1e-06	6	(AlkPhos)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	5q23.2	5	125907327	intergenic	AC116362.1			ENSG00000248752	NA	NA	rs1119582-?	rs1119582	1	465384	intron_variant	0	NR	1e-06	6	(CRP average 2,6,7)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	6q21	6	106451351	intergenic	CRYBG1			ENSG00000112297	NA	NA	rs1417352-?	rs1417352	0	1417352	intron_variant	0	NR	2e-06	5.69897000433602	(ANP6)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	10q21.1	10	53535114	intergenic	RNA5SP318 - AL365496.1	ENSG00000252161	ENSG00000233805		76826	231286	rs583012-?	rs583012	0	583012	intergenic_variant	1	NR	2e-06	5.69897000433602	(CRP2)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	13q14.11	13	40233346	intergenic	LINC00598			ENSG00000215483	NA	NA	rs10492681-?	rs10492681	0	10492681	intron_variant	0	NR	2e-06	5.69897000433602	(ALT)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	1q23.2	1	159178723	IGSF4B	CADM3			ENSG00000162706	NA	NA	rs1474747-?	rs1474747	0	1474747	intron_variant	0	NR	3e-06	5.52287874528034	(MCP1)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	7p21.3	7	10110349	intergenic	AC004936.1 - AC004879.1	ENSG00000287409	ENSG00000286639		24855	97321	rs7778619-?	rs7778619	0	7778619	intergenic_variant	1	NR	3e-06	5.52287874528034	(CD40L)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	1q23.2	1	159436169	OR10J1	AL513323.1			ENSG00000228560	NA	NA	rs4128725-?	rs4128725	0	4128725	intron_variant	0	NR	4e-12	11.397940008672	(MCP1)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	1q23.2	1	159709026	CRP	CRPP1 - CRP	ENSG00000223603	ENSG00000132693		3419	3263	rs2794520-?	rs2794520	0	2794520	intergenic_variant	1	NR	3e-08	7.52287874528034	(CRP average 2,6,7)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	1q23.2	1	159308461	FCER1A, OR10J3	FCER1A - OR10J3	ENSG00000179639	ENSG00000196266		237	5209	rs2494250-?	rs2494250	0	2494250	intergenic_variant	1	NR	1e-14	14	(MCP1)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	19q12	19	30608983	ZNF536	ZNF536			ENSG00000198597	NA	NA	rs746961-?	rs746961	0	746961	intron_variant	0	NR	8e-07	6.09691001300806	(CRP6)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	6q15	6	88403098	intergenic	AL139042.1			ENSG00000234426	NA	NA	rs10485165-?	rs10485165	0	10485165	intron_variant	0	NR	1e-06	6	(VitD25OH)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	7p12.3	7	46236130	intergenic	ZNF619P1 - AC023669.1	ENSG00000224547	ENSG00000229459		90442	24934	rs1486139-?	rs1486139	0	1486139	intergenic_variant	1	NR	2e-06	5.69897000433602	(ANP6)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	13q14.3	13	53393956	intergenic	AL450423.1, AL356295.1			ENSG00000273919, ENSG00000287722	NA	NA	rs10507577-?	rs10507577	0	10507577	intron_variant	0	NR	3e-06	5.52287874528034	(VitD25OH)	NA		Affymetrix [70897]	N
2008-09-11	17903293	Benjamin EJ	2007-09-19	BMC Med Genet	www.ncbi.nlm.nih.gov/pubmed/17903293	Genome-wide association with select biomarker traits in the Framingham Heart Study.	Select biomarker traits	1,012 European ancestry individuals	NA	14q23.2	14	61718577	intergenic	HIF1A, HIF1A-AS3			ENSG00000100644, ENSG00000258667	NA	NA	rs8005745-?	rs8005745	0	8005745	intron_variant	0	NR	4e-06	5.39794000867204	(CD40L)	NA		Affymetrix [70897]	N
2009-02-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Skin sensitivity to sun	2,986 individuals	3,932 individuals	11q14.3	11	89277878	TYR	TYR			ENSG00000077498	NA	NA	rs1393350-A	rs1393350	0	1393350	intron_variant	0	0.27	2e-06	5.69897000433602		1.26	[1.11-1.43]	Illumina [317511]	N
2009-02-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Skin sensitivity to sun	2,986 individuals	3,932 individuals	16q24.3	16	89919709	MC1R	MC1R, AC092143.1			ENSG00000258839, ENSG00000198211	NA	NA	rs1805007-T	rs1805007	0	1805007	missense_variant	0	0.06	2e-55	54.698970004336		2.94	[2.42-3.58]	Illumina [317511]	N
2009-02-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Red vs non-red hair color	2,986 individuals	3,932 individuals	16q24.3	16	89919709	MC1R	MC1R, AC092143.1			ENSG00000258839, ENSG00000198211	NA	NA	rs1805007-T	rs1805007	0	1805007	missense_variant	0	NR	2e-142	141.698970004336		12.47	[9.37-16.60]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Freckles	2,986 individuals	3,932 individuals	6p25.3	6	466033	SEC5L1, IRF4	AL512308.1			ENSG00000286364	NA	NA	rs1540771-A	rs1540771	0	1540771	intron_variant	0	0.42	4e-18	17.397940008672		1.4	[1.26-1.57]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Freckles	2,986 individuals	3,932 individuals	16q24.3	16	89919709	MC1R	MC1R, AC092143.1			ENSG00000258839, ENSG00000198211	NA	NA	rs1805007-T	rs1805007	0	1805007	missense_variant	0	0.05	1e-96	96		4.37	[3.56-5.37]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Freckles	2,986 individuals	3,932 individuals	11q14.3	11	89178528	TYR	TYR			ENSG00000077498	NA	NA	rs1042602-C	rs1042602	0	1042602	missense_variant	0	0.67	2e-11	10.698970004336		1.32	[1.17-1.49]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blond vs. brown hair color	2,986 European ancestry individuals	3,932 European ancestry individuals	14q32.12	14	92307319	SLC24A4	AL133240.2 - SLC24A4	ENSG00000286630	ENSG00000140090		9671	15262	rs12896399-T	rs12896399	0	12896399	intergenic_variant	1	0.44	1e-48	48		2.56	[2.12-3.09]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blond vs. brown hair color	2,986 European ancestry individuals	3,932 European ancestry individuals	16q24.3	16	89919709	MC1R	MC1R, AC092143.1			ENSG00000258839, ENSG00000198211	NA	NA	rs1805007-T	rs1805007	0	1805007	missense_variant	0	0.08	2e-13	12.698970004336		2.34	[1.69-3.24]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blond vs. brown hair color	2,986 European ancestry individuals	3,932 European ancestry individuals	15q13.1	15	28285036	OCA2	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs1667394-A	rs1667394	0	1667394	intron_variant	0	0.88	6e-35	34.2218487496164		4.94	[3.16-7.71]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blond vs. brown hair color	2,986 European ancestry individuals	3,932 European ancestry individuals	12q21.33	12	88934558	KITLG	AC024941.1 - LINC02458	ENSG00000278011	ENSG00000246363		332363	76123	rs12821256-C	rs12821256	0	12821256	TF_binding_site_variant	1	0.14	4e-30	29.397940008672		2.32	[1.86-2.92]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blue vs. green eyes	2,986 individuals	3,932 individuals	14q32.12	14	92307319	SLC24A4	AL133240.2 - SLC24A4	ENSG00000286630	ENSG00000140090		9671	15262	rs12896399-T	rs12896399	0	12896399	intergenic_variant	1	0.40	4e-38	37.397940008672		2.06	[1.76-2.42]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blue vs. green eyes	2,986 individuals	3,932 individuals	11q14.3	11	89277878	TYR	TYR			ENSG00000077498	NA	NA	rs1393350-A	rs1393350	0	1393350	intron_variant	0	0.23	3e-12	11.5228787452803		1.52	[1.28-1.81]	Illumina [317511]	N
2008-06-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blue vs. green eyes	2,986 individuals	3,932 individuals	15q13.1	15	28285036	OCA2	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs1667394-A	rs1667394	0	1667394	intron_variant	0	0.98	2e-53	52.698970004336		6.74	[4.61-9.83]	Illumina [317511]	N
2009-02-16	17952075	Sulem P	2007-10-21	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17952075	Genetic determinants of hair, eye and skin pigmentation in Europeans.	Blue vs. brown eyes	2,986 individuals	3,932 individuals	15q13.1	15	28285036	OCA2	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs1667394-A	rs1667394	0	1667394	intron_variant	0	0.88	1e-241	241		29.43	[21.47-40.35]	Illumina [317511]	N
2009-09-28	17997608	Li S	2007-11-09	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/17997608	The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts.	Urate levels	4,305 Sardinian individuals	1,301 European ancestry individuals	4p16.1	4	9934286	GLUT9	SLC2A9			ENSG00000109667	NA	NA	rs6855911-A	rs6855911	0	6855911	intron_variant	0	0.74	2e-16	15.698970004336		0.32	[NR] mg/dl increase	Affymetrix [362129]	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	13q14.11	13	43883789	Unknown	LACC1			ENSG00000179630	NA	NA	rs3764147-G	rs3764147	0	3764147	missense_variant	0	0.22	2e-13	12.698970004336		1.25	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	6q21	6	105987394	Unknown	RN7SKP211 - PRDM1	ENSG00000200198	ENSG00000057657		82707	6069	rs7746082-C	rs7746082	0	7746082	regulatory_region_variant	1	0.29	2e-10	9.69897000433602		1.17	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	1q23.3	1	160882256	ITLN1	ITLN1			ENSG00000179914	NA	NA	rs2274910-C	rs2274910	0	2274910	non_coding_transcript_exon_variant	0	0.68	1e-09	9		1.14	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	5q31.1	5	132435113	intergenic	C5orf56, AC116366.3			ENSG00000197536, ENSG00000283782	NA	NA	rs2188962-T	rs2188962	0	2188962	intron_variant	0	0.43	2e-18	17.698970004336		1.25	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	9q32	9	114804160	TNFSF15	TNFSF15			ENSG00000181634	NA	NA	rs4263839-G	rs4263839	0	4263839	intron_variant	0	0.68	3e-10	9.52287874528034		1.22	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	10q24.2	10	99531836	NKX2-3	LINC01475 - NKX2-3	ENSG00000257582	ENSG00000119919		659	1106	rs11190140-T	rs11190140	0	11190140	regulatory_region_variant	1	0.48	3e-16	15.5228787452803		1.2	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	18p11.21	18	12779948	PTPN2	AP005482.1 - PTPN2	ENSG00000260302	ENSG00000175354		3808	5530	rs2542151-G	rs2542151	0	2542151	intergenic_variant	1	0.15	5e-17	16.301029995664		1.35	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	5q33.3	5	159387525	IL12B	AC008691.1			ENSG00000249738	NA	NA	rs10045431-C	rs10045431	0	10045431	intron_variant	0	0.71	4e-13	12.397940008672		1.11	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	6q27	6	167024500	CCR6	FGFR1OP, Z94721.2			ENSG00000213066, ENSG00000272980	NA	NA	rs2301436-T	rs2301436	0	2301436	intron_variant	0	0.46	1e-12	12		1.21	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	17q21.2	17	42362183	STAT3	STAT3			ENSG00000168610	NA	NA	rs744166-A	rs744166	0	744166	intron_variant	0	0.57	7e-12	11.1549019599857		1.18	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	12q12	12	40208138	MUC19, LRRK2	LRRK2, AC079630.1, LINC02471			ENSG00000188906, ENSG00000225342, ENSG00000223914	NA	NA	rs11175593-T	rs11175593	0	11175593	non_coding_transcript_exon_variant	0	0.02	3e-10	9.52287874528034		1.54	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	9p24.1	9	4981602	JAK2	HNRNPA1P41 - JAK2	ENSG00000220937	ENSG00000096968		35700	2788	rs10758669-C	rs10758669	0	10758669	intergenic_variant	1	0.35	3e-09	8.52287874528034		1.12	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	3p21.31	3	49684099	MST1	MST1			ENSG00000173531	NA	NA	rs3197999-A	rs3197999	0	3197999	missense_variant	0	0.27	1e-12	12		1.2	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	5q33.1	5	150879305	IRGM	IRGM			ENSG00000237693	NA	NA	rs11747270-G	rs11747270	0	11747270	intron_variant	0	0.09	3e-16	15.5228787452803		1.33	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	16q12.1	16	50729868	NOD2	AC007728.2, NOD2			ENSG00000261644, ENSG00000167207	NA	NA	rs2066847-C	rs2066847	0	2066847	frameshift_variant	0	0.02	3e-24	23.5228787452803		3.99	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	10q21.2	10	62678726	ZNF365	AC024598.1 - AC067751.1	ENSG00000285837	ENSG00000238280		6715	3926	rs10995271-C	rs10995271	0	10995271	intergenic_variant	1	0.39	4e-20	19.397940008672		1.25	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	6p22.3	6	20728500	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs6908425-C	rs6908425	0	6908425	intron_variant	0	0.78	9e-10	9.04575749056067		1.21	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	8q24.13	8	125527809	intergenic	AC091114.1			ENSG00000253111	NA	NA	rs1551398-A	rs1551398	0	1551398	intron_variant	0	0.62	5e-09	8.30102999566398		1.08	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	1p13.2	1	113834946	PTPN22	PTPN22, AL137856.1			ENSG00000134242, ENSG00000231128	NA	NA	rs2476601-G	rs2476601	0	2476601	missense_variant	0	0.90	1e-08	8		1.31	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	1q24.3	1	172893094	intergenic	AL031599.1			ENSG00000224228	NA	NA	rs9286879-G	rs9286879	0	9286879	intron_variant	0	0.24	2e-09	8.69897000433602		1.19	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	1q32.1	1	200966738	intergenic	MROH3P - KIF21B	ENSG00000233217	ENSG00000116852		70	2652	rs11584383-T	rs11584383	0	11584383	intergenic_variant	1	0.70	1e-11	11		1.18	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	7p12.2	7	50230076	intergenic	AC020743.2			ENSG00000231681	NA	NA	rs1456893-A	rs1456893	0	1456893	intron_variant	0	0.68	5e-09	8.30102999566398		1.2	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	10p11.21	10	34998722	intergenic	LINC02635 - CUL2	ENSG00000283000	ENSG00000108094		23144	9829	rs17582416-G	rs17582416	0	17582416	regulatory_region_variant	1	0.35	2e-09	8.69897000433602		1.16	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	11q13.5	11	76590272	C11orf30	EMSY - AP001189.2	ENSG00000158636	ENSG00000254755		37247	751	rs7927894-T	rs7927894	0	7927894	intergenic_variant	1	0.39	1e-09	9		1.16	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	17q21.1	17	39884510	ORMDL3	ZPBP2 - GSDMB	ENSG00000186075	ENSG00000073605		6614	20085	rs2872507-A	rs2872507	0	2872507	intergenic_variant	1	0.47	5e-09	8.30102999566398		1.12	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q26.12	10	120283977	NR	AL355298.1 - RPL21P16	ENSG00000223455	ENSG00000220842		213818	70724	rs11199254-C	rs11199254	0	11199254	intergenic_variant	1	0.994452838362069	3e-06	5.52287874528034	(IGP39)	1.5568	[0.9-2.21] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q11.22	7	69773172	NR	AUTS2			ENSG00000158321	NA	NA	rs11765886-C	rs11765886	0	11765886	intron_variant	0	0.665165836680053	4e-06	5.39794000867204	(IGP39)	0.1625	[0.094-0.231] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39343633	NR	RPL3 - SYNGR1	ENSG00000100316	ENSG00000100321		23244	6292	rs137686-C	rs137686	0	137686	TF_binding_site_variant	1	0.24173856626506	1e-11	11	(IGP39)	0.2524	[0.18-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189518247657296	1e-10	10	(IGP39)	0.267	[0.19-0.35] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p12	2	76996812	NR	AC079117.1, LRRTM4			ENSG00000234653, ENSG00000176204	NA	NA	rs1470506-C	rs1470506	0	1470506	intron_variant	0	0.595063458147818	4e-07	6.39794000867204	(IGP65)	0.16	[0.098-0.222] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p16.1	4	7016458	NR	TBC1D14			ENSG00000132405	NA	NA	rs16839553-G	rs16839553	0	16839553	intron_variant	0	0.992978201291118	8e-06	5.09691001300806	(IGP65)	1.1375	[0.64-1.64] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q15	6	88543930	NR	AL139042.1 - RNGTT	ENSG00000234426	ENSG00000111880		101002	65967	rs2610739-G	rs2610739	0	2610739	intergenic_variant	1	0.187486864203028	4e-06	5.39794000867204	(IGP65)	0.1852	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30711851	NR	MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1			ENSG00000224587, ENSG00000225589, ENSG00000231135, ENSG00000137337, ENSG00000237095, ENSG00000228575, ENSG00000234012, ENSG00000206481, ENSG00000236522, ENSG00000236766, ENSG00000227899, ENSG00000224328, ENSG00000229681, ENSG00000231860, ENSG00000233883, ENSG00000224508	NA	NA	rs3094093-T	rs3094093	0	3094093	intron_variant	0	0.107712365538735	8e-06	5.09691001300806	(IGP65)	0.2214	[0.12-0.32] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	95911056	NR	ELL2			ENSG00000118985	NA	NA	rs3777193-G	rs3777193	0	3777193	intron_variant	0	0.71211365048976	4e-06	5.39794000867204	(IGP65)	0.1592	[0.092-0.227] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q22.1	2	140984021	NR	LRP1B			ENSG00000168702	NA	NA	rs4954683-C	rs4954683	0	4954683	intron_variant	0	0.172162723953695	9e-06	5.04575749056067	(IGP65)	0.1823	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368121119768477	5e-07	6.30102999566398	(IGP65)	0.1615	[0.099-0.224] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q23.3	2	152580056	NR	FMNL2			ENSG00000157827	NA	NA	rs11675841-C	rs11675841	0	11675841	intron_variant	0	0.607345676902537	6e-06	5.22184874961636	(IGP66)	0.1448	[0.082-0.208] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13319976	NR	SEPHS1			ENSG00000086475	NA	NA	rs1747683-G	rs1747683	0	1747683	intron_variant	0	0.414548764129951	2e-07	6.69897000433602	(IGP66)	0.1661	[0.1-0.23] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	NR	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	9e-17	16.0457574905607	(IGP66)	0.3473	[0.27-0.43] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50295636	NR	AC020743.3 - IKZF1	ENSG00000235620	ENSG00000185811		20014	8432	rs4917017-G	rs4917017	0	4917017	intergenic_variant	1	0.70576580729862	2e-07	6.69897000433602	(IGP66)	0.1816	[0.11-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q11.22	20	33968971	NR	PIGPP3 - RALY-AS1	ENSG00000228958	ENSG00000285230		3395	11708	rs6059594-G	rs6059594	0	6059594	intergenic_variant	1	0.962797338540276	9e-06	5.04575749056067	(IGP66)	0.4792	[0.27-0.69] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	1e-16	16	(IGP66)	0.281	[0.21-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17p11.2	17	17239582	NR	FLCN - ACTG1P24	ENSG00000154803	ENSG00000226359		2394	2428	rs12600635-G	rs12600635	0	12600635	intergenic_variant	1	0.145679882058288	4e-07	6.39794000867204	(IGP41)	0.2221	[0.14-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32706960	NR	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		5	11045	rs1794265-C	rs1794265	0	1794265	intergenic_variant	1	0.945425811930783	3e-07	6.52287874528034	(IGP41)	0.3448	[0.21-0.48] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16p12.3	16	20019883	NR	GPRC5B - GPR139	ENSG00000167191	ENSG00000180269		133716	11602	rs2764743-T	rs2764743	0	2764743	intergenic_variant	1	0.936472894262295	8e-07	6.09691001300806	(IGP41)	0.346	[0.21-0.48] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	21q22.3	21	41421864	NR	MX1			ENSG00000157601	NA	NA	rs459482-C	rs459482	0	459482	5_prime_UTR_variant	0	0.594327337431694	3e-07	6.52287874528034	(IGP41)	0.1627	[0.1-0.22] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31834688	NR	SNHG32, SNHG32, SNHG32, SNHG32, AL671762.1			ENSG00000226710, ENSG00000234728, ENSG00000204387, ENSG00000229300, ENSG00000285565	NA	NA	rs4711279-C	rs4711279	0	4711279	5_prime_UTR_variant	0	0.824607758652095	1e-06	6	(IGP41)	0.1858	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q13.2	11	68164294	SUV420H1	KMT5B			ENSG00000110066	NA	NA	rs4930561-G	rs4930561	0	4930561	intron_variant	0	0.511382618397086	9e-10	9.04575749056067	(IGP41)	0.185	[0.13-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p13.31	12	7182217	NR	AC018653.1			ENSG00000255572	NA	NA	rs7973719-C	rs7973719	0	7973719	intron_variant	0	0.487491611566485	4e-08	7.39794000867204	(IGP41)	0.1772	[0.11-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q21.1	18	48714340	NR	CTIF			ENSG00000134030	NA	NA	rs9947954-C	rs9947954	0	9947954	intron_variant	0	0.425160203096539	8e-06	5.09691001300806	(IGP41)	0.1398	[0.078-0.201] unit decrease	Illumina [~ 2500000] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	21q22.3	21	44195678	ICOSLG	GATD3A			ENSG00000160221	NA	NA	rs762421-G	rs762421	0	762421	intron_variant	0	0.39	1e-09	9		1.13	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	1p31.3	1	67236843	IL23R	IL23R			ENSG00000162594	NA	NA	rs11465804-T	rs11465804	0	11465804	intron_variant	0	0.93	7e-63	62.1549019599857		2.5	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	2q37.1	2	233271764	ATG16L1	ATG16L1, ATG16L1			ENSG00000085978, ENSG00000281089	NA	NA	rs3828309-G	rs3828309	0	3828309	intron_variant	0	0.53	2e-32	31.698970004336		1.25	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	5p13.1	5	40392626	PTGER4	AC108105.1 - AC093277.1	ENSG00000287597	ENSG00000283286		79721	22511	rs4613763-C	rs4613763	0	4613763	regulatory_region_variant	1	0.13	7e-27	26.1549019599857		1.32	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18587394	Barrett JC	2008-06-29	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18587394	Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.	Crohn's disease	3,230 European ancestry cases, 4,829 European ancestry controls	1,339 European ancestry trios, 2,325 European ancestry cases, 1,809 European ancestry controls	21q21.1	21	15432901	intergenic	AJ009632.2			ENSG00000229425	NA	NA	rs1736135-T	rs1736135	0	1736135	intron_variant	0	0.57	7e-09	8.15490195998574		1.18	[NR]	Affymetrix, Illumina [635547] (imputed)	N
2008-07-11	18576341	Behrens EM	2008-06-24	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/18576341	Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis.	Arthritis (juvenile idiopathic)	67 European ancestry cases, 1,952 European ancestry controls, 63 cases	NA	6p21.32	6	32353777	HLA-DRB1	TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1, TSBP1-AS1			ENSG00000234280, ENSG00000232106, ENSG00000206245, ENSG00000204296, ENSG00000206310, ENSG00000226892, ENSG00000237881, ENSG00000236672, ENSG00000225914	NA	NA	rs2395148-?	rs2395148	0	2395148	intron_variant	0	NR	2e-10	9.69897000433602		5.37	[3.02-9.56]	Illumina [524684]	N
2008-11-12	18849991	Richards JB	2008-10-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18849991	Male-pattern baldness susceptibility locus at 20p11.	Male-pattern baldness	578 European ancestry cases, 547 European ancestry controls	1,351 European ancestry cases, 2,485 European ancestry controls	Xq12	X	67291142	AR	RNU6-394P - AL049641.1	ENSG00000222667	ENSG00000226280		614778	82431	rs6625163-A	rs6625163	0	6625163	intergenic_variant	1	NR	5e-11	10.301029995664		3.3	[2.31-4.71]	Affymetrix [370102]	N
2008-11-12	18849991	Richards JB	2008-10-12	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/18849991	Male-pattern baldness susceptibility locus at 20p11.	Male-pattern baldness	578 European ancestry cases, 547 European ancestry controls	1,351 European ancestry cases, 2,485 European ancestry controls	20p11.22	20	22069865	PAX1	LINC01432			ENSG00000234435	NA	NA	rs1160312-A	rs1160312	0	1160312	intron_variant	0	0.43	1e-14	14	(males)	1.6	[1.42-1.80]	Affymetrix [370102]	N
2010-06-14	20463881	Liu F	2010-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20463881	Digital quantification of human eye color highlights genetic association of three new loci.	Eye color traits	5,951 European ancestry individuals	3,543 European ancestry individuals	21q22.13	21	37118795	TTC3, DSCR9	TTC3			ENSG00000182670	NA	NA	rs1003719-A	rs1003719	0	1003719	intron_variant	0	NR	2e-10	9.69897000433602	(CHS1)	0.1	[NR] % decrease	Illumina [2543887] (imputed)	N
2010-06-14	20463881	Liu F	2010-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20463881	Digital quantification of human eye color highlights genetic association of three new loci.	Eye color traits	5,951 European ancestry individuals	3,543 European ancestry individuals	15q13.1	15	28120472	HERC2, OCA	HERC2, HERC2			ENSG00000276802, ENSG00000128731	NA	NA	rs12913832-?	rs12913832	0	12913832	intron_variant	0	NR	1e-300	300	(RS123 cohort)	NA		Illumina [2543887] (imputed)	N
2010-06-14	20463881	Liu F	2010-05-16	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/20463881	Digital quantification of human eye color highlights genetic association of three new loci.	Eye color traits	5,951 European ancestry individuals	3,543 European ancestry individuals	17q25.3	17	81629785	NPLOC4, HGS	NPLOC4			ENSG00000182446	NA	NA	rs9894429-T	rs9894429	0	9894429	synonymous_variant	0	NR	9e-14	13.0457574905607	(CHS1)	0.12	[NR] % increase	Illumina [2543887] (imputed)	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	10q24.2	10	99528007	NKX2-3	AL513542.1, LINC01475			ENSG00000228778, ENSG00000257582	NA	NA	rs10883365-G	rs10883365	0	10883365	non_coding_transcript_exon_variant	0	0.48	6e-08	7.22184874961636		1.2	[1.03-1.39]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	22q12.3	22	37155567	NR	IL2RB			ENSG00000100385	NA	NA	rs743777-G	rs743777	0	743777	intron_variant	0	0.29	1e-06	6		1.09	[0.97-1.24]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	21q22.2	21	41139991	NR	AL773573.1 - LINC00323	ENSG00000286425	ENSG00000226496		102629	1502	rs2837960-G	rs2837960	0	2837960	intergenic_variant	1	0.17	2e-06	5.69897000433602		1.05	[0.93-1.20]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	1p13.2	1	113761186	PTPN22	PHTF1 - RSBN1	ENSG00000116793	ENSG00000081019		1697	646	rs6679677-A	rs6679677	0	6679677	intergenic_variant	1	0.10	6e-25	24.2218487496164		1.98	[1.72-2.27]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	6p21.32	6	32696074	MHC	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		27691	10050	rs6457617-T	rs6457617	0	6457617	intergenic_variant	1	0.49	5e-75	74.301029995664		2.36	[1.97-2.84]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Coronary heart disease	1,926 European ancestry cases, 2,938 European ancestry controls	(see Samani 2007)	9p21.3	9	22125504	CDKN2A, CDKN2B	CDKN2B-AS1			ENSG00000240498	NA	NA	rs1333049-C	rs1333049	0	1333049	intron_variant	0	0.47	1e-13	13		1.47	[1.27-1.70]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	5q31.1	5	132406536	intergenic	SLC22A5 - C5orf56	ENSG00000197375	ENSG00000197536		10922	4100	rs6596075-C	rs6596075	0	6596075	intergenic_variant	1	0.17	3e-06	5.52287874528034		1.55	[1.00-2.39]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	2q37.1	2	233250193	ATG16L1	ATG16L1, ATG16L1			ENSG00000085978, ENSG00000281089	NA	NA	rs10210302-T	rs10210302	0	10210302	intron_variant	0	0.48	5e-14	13.301029995664		1.19	[1.01-1.41]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	3p21.31	3	49664550	MST1, BSN	BSN			ENSG00000164061	NA	NA	rs9858542-A	rs9858542	0	9858542	synonymous_variant	0	0.28	4e-08	7.39794000867204		1.09	[0.96-1.24]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	5q33.1	5	150860514	IRGM	IRGM			ENSG00000237693	NA	NA	rs1000113-T	rs1000113	0	1000113	intron_variant	0	0.07	3e-07	6.52287874528034		1.54	[1.31-1.82]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	18p11.21	18	12779948	PTPN2	AP005482.1 - PTPN2	ENSG00000260302	ENSG00000175354		3808	5530	rs2542151-G	rs2542151	0	2542151	intergenic_variant	1	0.16	2e-07	6.69897000433602		1.3	[1.14-1.48]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	6p21.32	6	32690533	NR	HLA-DQB1 - MTCO3P1	ENSG00000231286	ENSG00000237145		22150	15591	rs9469220-A	rs9469220	0	9469220	TF_binding_site_variant	1	0.48	2e-06	5.69897000433602		1.14	[0.98-1.32]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	10p15.1	10	3820350	NR	AL513303.1 - LINC02639	ENSG00000287175	ENSG00000230573		4181	13600	rs6601764-C	rs6601764	0	6601764	regulatory_region_variant	1	0.41	9e-06	5.04575749056067		1.16	[1.01-1.33]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	20p13	20	3795528	NR	CDC25B			ENSG00000101224	NA	NA	rs3761218-C	rs3761218	0	3761218	intron_variant	0	0.64	7e-06	5.15490195998574		1.03	[1.15-1.23]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	16p12.2	16	23622705	DCTN5, PALB2, NDUFAB1	PALB2, AC008870.4			ENSG00000083093, ENSG00000261723	NA	NA	rs420259-A	rs420259	0	420259	intron_variant	0	0.72	6e-08	7.22184874961636		2.08	[1.60-2.71]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	1p31.3	1	67209833	IL23R	C1orf141, IL23R			ENSG00000203963, ENSG00000162594	NA	NA	rs11805303-T	rs11805303	0	11805303	intron_variant	0	0.32	6e-12	11.2218487496164		1.39	[1.22-1.58]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Hypertension	1,952 European ancestry cases, 2,938 European ancestry controls	NA	1q43	1	239273242	CHRM3, ZP4, RYR2	AC093426.1 - CHRM3	ENSG00000259776	ENSG00000133019		22424	113323	rs2820037-T	rs2820037	0	2820037	intergenic_variant	1	0.14	8e-07	6.09691001300806		1.54	[1.03-2.31]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Hypertension	1,952 European ancestry cases, 2,938 European ancestry controls	NA	15q26.2	15	96287321	intergenic	AC012409.2, NR2F2-AS1			ENSG00000275443, ENSG00000247809	NA	NA	rs2398162-A	rs2398162	0	2398162	non_coding_transcript_exon_variant	0	0.74	6e-06	5.22184874961636		1.31	[1.03-1.67]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	12q24.13	12	112049014	SH2B3, TRAFD1, PTPN11, LNK	NAA25			ENSG00000111300	NA	NA	rs17696736-G	rs17696736	0	17696736	intron_variant	0	0.42	2e-14	13.698970004336		1.34	[1.16-1.53]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	6p22.3	6	20717024	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs9465871-C	rs9465871	0	9465871	intron_variant	0	0.18	3e-07	6.52287874528034		1.18	[1.04-1.34]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	1p13.2	1	113761186	PTPN22	PHTF1 - RSBN1	ENSG00000116793	ENSG00000081019		1697	646	rs6679677-A	rs6679677	0	6679677	intergenic_variant	1	0.10	5e-26	25.301029995664		1.82	[1.59-2.09]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	3p14.3	3	55279372	NR	LINC02030			ENSG00000240708	NA	NA	rs358806-?	rs358806	0	358806	intron_variant	0	0.80	3e-06	5.52287874528034		1.16	[1.03-1.33]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	12q13.12	12	50963759	NR	HIGD1C			ENSG00000214511	NA	NA	rs12304921-G	rs12304921	0	12304921	intron_variant	0	0.15	7e-06	5.15490195998574		2.5	[1.53-4.09]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	10q25.2	10	112996282	TCF7L2	TCF7L2			ENSG00000148737	NA	NA	rs4506565-T	rs4506565	0	4506565	intron_variant	0	0.32	5e-12	11.301029995664		1.36	[1.20-1.54]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	4q27	4	121744359	NR	ANXA5 - TMEM155	ENSG00000164111	ENSG00000164112		47364	14571	rs7659604-T	rs7659604	0	7659604	intergenic_variant	1	0.38	9e-06	5.04575749056067		1.35	[1.19-1.54]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	4p15.2	4	25415622	NR	ANAPC4			ENSG00000053900	NA	NA	rs3816587-C	rs3816587	0	3816587	non_coding_transcript_exon_variant	0	0.41	9e-06	5.04575749056067		1.09	[0.96-1.25]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	12p13.31	12	9681032	NR	CLEC2D			ENSG00000069493	NA	NA	rs3764021-C	rs3764021	0	3764021	splice_region_variant	0	0.47	5e-08	7.30102999566398		1.57	[1.38-1.79]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	5q31.1	5	133293192	NR	FSTL4			ENSG00000053108	NA	NA	rs17166496-G	rs17166496	0	17166496	intron_variant	0	0.61	5e-06	5.30102999566398		1.3	[1.15-1.47]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	6p21.32	6	32636595	MHC	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs9272346-G	rs9272346	0	9272346	intron_variant	0	0.61	5e-134	133.301029995664		5.49	[4.83-6.24]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	7q36.1	7	148560956	NR	AC006974.2			ENSG00000283648	NA	NA	rs7807268-G	rs7807268	0	7807268	intron_variant	0	0.46	4e-06	5.39794000867204		1.38	[1.20-1.60]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Coronary heart disease	1,926 European ancestry cases, 2,938 European ancestry controls	(see Samani 2007)	1q43	1	240282296	intergenic	FMN2			ENSG00000155816	NA	NA	rs17672135-T	rs17672135	0	17672135	intron_variant	0	0.87	2e-06	5.69897000433602		1.43	[1.23-1.64]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Coronary heart disease	1,926 European ancestry cases, 2,938 European ancestry controls	(see Samani 2007)	22q12.1	22	26293669	intergenic	SEZ6L			ENSG00000100095	NA	NA	rs688034-T	rs688034	0	688034	intron_variant	0	0.31	4e-06	5.39794000867204		1.11	[0.99-1.25]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Coronary heart disease	1,926 European ancestry cases, 2,938 European ancestry controls	(see Samani 2007)	16q23.3	16	83178793	intergenic	CDH13			ENSG00000140945	NA	NA	rs8055236-G	rs8055236	0	8055236	intron_variant	0	0.80	6e-06	5.22184874961636		1.91	[1.33-2.74]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	6p21.1	6	42763377	NR	BICRAL			ENSG00000112624	NA	NA	rs6458307-?	rs6458307	0	6458307	intron_variant	0	0.69	4e-06	5.39794000867204		1.19	[1.04-1.33]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	3q27.1	3	183152030	NR	LAMP3			ENSG00000078081	NA	NA	rs683395-G	rs683395	0	683395	intron_variant	0	0.08	5e-06	5.30102999566398		1.47	[1.26-1.71]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	2q37.3	2	240576179	NR	RNPEPL1			ENSG00000142327	NA	NA	rs2953145-C	rs2953145	0	2953145	non_coding_transcript_exon_variant	0	0.23	7e-06	5.15490195998574		1.84	[1.31-2.58]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	16q12.1	16	50705671	NOD2	NOD2			ENSG00000167207	NA	NA	rs17221417-G	rs17221417	0	17221417	intron_variant	0	0.29	4e-11	10.397940008672		1.29	[1.13-1.46]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	5p13.1	5	40401407	intergenic	AC108105.1 - AC093277.1	ENSG00000287597	ENSG00000283286		88502	13730	rs17234657-G	rs17234657	0	17234657	intergenic_variant	1	0.13	2e-12	11.698970004336		1.54	[1.34-1.76]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Crohn's disease	1,748 European ancestry cases, 2,938 European ancestry controls	(see Parkes 2007)	10q21.2	10	62685804	intergenic	AC067751.1			ENSG00000238280	NA	NA	rs10761659-G	rs10761659	0	10761659	intron_variant	0	0.46	2e-06	5.69897000433602		1.23	[1.05-1.45]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	14q23.1	14	57652478	NR	SLC35F4			ENSG00000151812	NA	NA	rs10134944-T	rs10134944	0	10134944	intron_variant	0	0.09	7e-06	5.15490195998574		1.45	[1.24-1.68]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Bipolar disorder	1,868 European ancestry cases, 2,938 European ancestry controls	NA	14q32.33	14	104042739	NR	TDRD9			ENSG00000156414	NA	NA	rs11622475-C	rs11622475	0	11622475	intron_variant	0	0.70	8e-06	5.09691001300806		1.13	[0.89-1.44]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	12q21.1	12	71183321	NR	TSPAN8			ENSG00000127324	NA	NA	rs1495377-G	rs1495377	0	1495377	intron_variant	0	0.50	7e-06	5.15490195998574		1.28	[1.11-1.49]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	4q27	4	122277280	NR	KIAA1109			ENSG00000138688	NA	NA	rs6534347-A	rs6534347	0	6534347	intron_variant	0	0.35	2e-06	5.69897000433602		1.3	[1.10-1.55]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 2 diabetes	1,924 European ancestry cases, 2,938 European ancestry controls	(see Zeggini 2007)	16q12.2	16	53786615	FTO	FTO			ENSG00000140718	NA	NA	rs9939609-A	rs9939609	0	9939609	intron_variant	0	0.40	2e-07	6.69897000433602		1.34	[1.17-1.52]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	12q13.2	12	56076841	ERBB3	ERBB3			ENSG00000065361	NA	NA	rs11171739-C	rs11171739	0	11171739	5_prime_UTR_variant	0	0.42	1e-11	11		1.34	[1.17-1.54]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	16p13.13	16	11086016	KIAA0350	CLEC16A			ENSG00000038532	NA	NA	rs12708716-A	rs12708716	0	12708716	intron_variant	0	0.65	5e-07	6.30102999566398		1.19	[0.97-1.45]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	12p13.31	12	9703362	NR	CLEC2D - LINC02390	ENSG00000069493	ENSG00000256582		3809	715	rs11052552-G	rs11052552	0	11052552	intergenic_variant	1	0.49	7e-07	6.15490195998574		1.49	[1.28-1.73]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Type 1 diabetes	1,963 European ancestry cases, 2,938 European ancestry controls	(see Todd 2007)	4q27	4	122408207	NR	ADAD1			ENSG00000164113	NA	NA	rs17388568-A	rs17388568	0	17388568	intron_variant	0	0.26	3e-06	5.52287874528034		1.26	[1.11-1.42]	Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	6p21.32	6	32606394	HLA-DRB1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		16546	21785	rs615672-?	rs615672	0	615672	intron_variant	1	NR	8e-27	26.0969100130081		NA		Affymetrix [469557]	N
2008-06-16	17554300	Wellcome Trust Case Control Consortium	2007-06-07	Nature	www.ncbi.nlm.nih.gov/pubmed/17554300	Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.	Rheumatoid arthritis	1,860 European ancestry cases, 2,938 European ancestry controls	NA	7q32.3	7	131685280	intergenic	AC093106.1 - AC093106.2	ENSG00000236238	ENSG00000236395		19422	16989	rs11761231-G	rs11761231	0	11761231	intergenic_variant	1	0.62	4e-07	6.39794000867204	(sex-differentiated)	1.44	[1.19-1.75]	Affymetrix [469557]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	81244914	NR	SLC38A10			ENSG00000157637	NA	NA	rs2659005-C	rs2659005	0	2659005	3_prime_UTR_variant	0	0.517316186025812	2e-06	5.69897000433602	(IGP17)	0.1537	[0.09-0.217] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p14	10	7845658	NR	TAF3			ENSG00000165632	NA	NA	rs11255400-G	rs11255400	0	11255400	intron_variant	0	0.931314253351327	7e-06	5.15490195998574	(IGP2)	0.2863	[0.16-0.41] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q22.2	15	62046598	NR	VPS13C			ENSG00000129003	NA	NA	rs1436958-G	rs1436958	0	1436958	intron_variant	0	0.57353197705803	9e-06	5.04575749056067	(IGP2)	0.1389	[0.078-0.2] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q13.3	15	33201020	NR	FMN1 - TMCO5B	ENSG00000248905	ENSG00000215296		6287	34532	rs6494964-G	rs6494964	0	6494964	intergenic_variant	1	0.686050906432748	6e-06	5.22184874961636	(IGP2)	0.1846	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q43	1	242358740	NR	PLD5			ENSG00000180287	NA	NA	rs2919024-G	rs2919024	0	2919024	intron_variant	0	0.012337327027027	7e-06	5.15490195998574	(IGP20)	0.6788	[0.38-0.97] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q14.3	6	86897124	NR	AL157777.1			ENSG00000217769	NA	NA	rs1853639-G	rs1853639	0	1853639	non_coding_transcript_exon_variant	0	0.359453092898615	8e-06	5.09691001300806	(IGP21)	0.1761	[0.099-0.254] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q36.1	7	151217985	ABCF2, SMARCD3	ABCF2, ABCF2			ENSG00000285292, ENSG00000033050	NA	NA	rs1122979-G	rs1122979	0	1122979	intron_variant	0	0.874862054831461	1e-09	9	(IGP42)	0.2982	[0.2-0.39] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p12	8	31176759	NR	AC009563.1			ENSG00000253961	NA	NA	rs11774682-C	rs11774682	0	11774682	non_coding_transcript_exon_variant	0	0.966180189368771	3e-06	5.52287874528034	(IGP42)	0.8017	[0.47-1.14] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.391170597752809	3e-21	20.5228787452803	(IGP42)	0.3025	[0.24-0.37] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	30711851	NR	MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1, MDC1-AS1			ENSG00000224587, ENSG00000225589, ENSG00000231135, ENSG00000137337, ENSG00000237095, ENSG00000228575, ENSG00000234012, ENSG00000206481, ENSG00000236522, ENSG00000236766, ENSG00000227899, ENSG00000224328, ENSG00000229681, ENSG00000231860, ENSG00000233883, ENSG00000224508	NA	NA	rs3094093-T	rs3094093	0	3094093	intron_variant	0	0.107325880449438	3e-06	5.52287874528034	(IGP42)	0.2336	[0.14-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32985503	NR	BRD2 - HLA-DOA	ENSG00000215077	ENSG00000230141		3998	18679	rs3097645-C	rs3097645	0	3097645	regulatory_region_variant	1	0.874270331235955	2e-06	5.69897000433602	(IGP42)	0.2151	[0.13-0.3] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.33	6	31962664	NR	SKIV2L			ENSG00000225737	NA	NA	rs592229-G	rs592229	0	592229	intron_variant	0	0.370399655280899	4e-06	5.39794000867204	(IGP42)	0.1536	[0.088-0.219] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.299013119715176	1e-24	24	(IGP40)	0.3447	[0.28-0.41] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q12.1	2	102772135	NR	TMEM182			ENSG00000170417	NA	NA	rs12465996-C	rs12465996	0	12465996	intron_variant	0	0.864380324681238	5e-06	5.30102999566398	(IGP41)	0.2423	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q13.3	15	33201020	NR	FMN1 - TMCO5B	ENSG00000248905	ENSG00000215296		6287	34532	rs6494964-G	rs6494964	0	6494964	intergenic_variant	1	0.685883860674157	8e-06	5.09691001300806	(IGP42)	0.1819	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50310671	NR	IKZF1			ENSG00000185811	NA	NA	rs6583437-G	rs6583437	0	6583437	intron_variant	0	0.636802753258427	7e-10	9.15490195998574	(IGP42)	0.197	[0.13-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q31.1	5	132386057	NR	SLC22A5			ENSG00000197375	NA	NA	rs7731390-C	rs7731390	0	7731390	intron_variant	0	0.947771454651685	2e-06	5.69897000433602	(IGP42)	0.3846	[0.23-0.54] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q32.3	1	214283666	NR	SMYD2			ENSG00000143499	NA	NA	rs9308433-C	rs9308433	0	9308433	intron_variant	0	0.408306478651685	2e-06	5.69897000433602	(IGP42)	0.1494	[0.088-0.211] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p25.3	2	1554155	NR	AC141930.2, AC141930.1, AC105450.1			ENSG00000283766, ENSG00000228613, ENSG00000231482	NA	NA	rs10206020-C	rs10206020	0	10206020	intron_variant	0	0.188382478860703	3e-06	5.52287874528034	(IGP43)	0.1805	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33153529	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813957-G	rs10813957	0	10813957	intron_variant	0	0.738414638629283	7e-06	5.15490195998574	(IGP43)	0.1601	[0.09-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q21.1	18	48701073	NR	CTIF			ENSG00000134030	NA	NA	rs16949825-C	rs16949825	0	16949825	intron_variant	0	0.902274750778816	3e-06	5.52287874528034	(IGP43)	0.2547	[0.15-0.36] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.122643248331108	6e-06	5.22184874961636	(IGP43)	0.2172	[0.12-0.31] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8p22	8	14256307	NR	SGCZ			ENSG00000185053	NA	NA	rs9886428-G	rs9886428	0	9886428	intron_variant	0	0.455051607476636	1e-06	6	(IGP43)	0.1476	[0.088-0.208] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.11	14	89760907	NR	AL137230.2			ENSG00000259053	NA	NA	rs2093746-C	rs2093746	0	2093746	intron_variant	0	0.265047574785359	2e-07	6.69897000433602	(IGP44)	0.2917	[0.18-0.4] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q15	6	89948064	BACH2	BACH2			ENSG00000112182	NA	NA	rs404256-C	rs404256	0	404256	intron_variant	0	0.55888563217352	5e-06	5.30102999566398	(IGP44)	0.1659	[0.095-0.237] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.2	3	153760634	NR	LINC02006			ENSG00000238755	NA	NA	rs6794649-C	rs6794649	0	6794649	intron_variant	0	0.159404027112517	2e-06	5.69897000433602	(IGP44)	0.2013	[0.12-0.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4p15.31	4	21204867	NR	KCNIP4			ENSG00000185774	NA	NA	rs1023721-T	rs1023721	0	1023721	intron_variant	0	0.941491348153093	1e-06	6	(IGP45)	0.312	[0.19-0.44] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q36.1	7	151217985	ABCF2, SMARCD3	ABCF2, ABCF2			ENSG00000285292, ENSG00000033050	NA	NA	rs1122979-G	rs1122979	0	1122979	intron_variant	0	0.875396395193591	6e-10	9.22184874961636	(IGP45)	0.3046	[0.21-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q22.32	9	96054202	NR	ERCC6L2			ENSG00000182150	NA	NA	rs1547201-C	rs1547201	0	1547201	intron_variant	0	0.530022081441923	7e-06	5.15490195998574	(IGP45)	0.1416	[0.08-0.203] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56028975	NR	AC008892.1			ENSG00000249236	NA	NA	rs16884711-C	rs16884711	0	16884711	intron_variant	0	0.188959846461949	3e-06	5.52287874528034	(IGP45)	0.1908	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	4e-06	5.39794000867204	(IGP45)	0.1924	[0.11-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32146738	PRRT1	FKBPL - PRRT1	ENSG00000230907	ENSG00000227122		16450	1621	rs9296009-T	rs9296009	0	9296009	regulatory_region_variant	1	0.196432337204109	4e-08	7.39794000867204	(IGP23)	0.2111	[0.14-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	81244914	NR	SLC38A10			ENSG00000157637	NA	NA	rs2659005-C	rs2659005	0	2659005	3_prime_UTR_variant	0	0.517358149665924	3e-07	6.52287874528034	(IGP24)	0.1648	[0.1-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.4	11	5666794	NR	TRIM5, AC104389.5			ENSG00000132256, ENSG00000239920	NA	NA	rs11820502-C	rs11820502	0	11820502	intron_variant	0	0.287492850713013	1e-06	6	(IGP25)	0.1836	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q21.2	7	91610982	NR	AC079760.1 - AC000058.1	ENSG00000235450	ENSG00000223665		54134	27865	rs2540552-C	rs2540552	0	2540552	intergenic_variant	1	0.58104074197861	8e-06	5.09691001300806	(IGP25)	0.1381	[0.078-0.199] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p12	11	41204404	NR	LRRC4C			ENSG00000148948	NA	NA	rs980952-G	rs980952	0	980952	intron_variant	0	0.975374875668449	5e-06	5.30102999566398	(IGP25)	0.4489	[0.26-0.64] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q21.13	8	75124209	NR	CRISPLD1 - AC022274.1	ENSG00000121005	ENSG00000253712		89651	43495	rs1531590-C	rs1531590	0	1531590	intergenic_variant	1	0.227292733303651	3e-06	5.52287874528034	(IGP26)	0.1794	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	80092818	NR	CCDC40			ENSG00000141519	NA	NA	rs2361701-G	rs2361701	0	2361701	intron_variant	0	0.823049887254902	4e-06	5.39794000867204	(IGP28)	0.1856	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.699317446770601	6e-75	74.2218487496164	(IGP29)	0.6427	[0.57-0.71] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q14.1	5	79647825	NR	TENT2			ENSG00000164329	NA	NA	rs6859704-C	rs6859704	0	6859704	intron_variant	0	0.0769240376391982	8e-06	5.09691001300806	(IGP29)	0.2598	[0.15-0.37] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2p25.3	2	1554155	NR	AC141930.2, AC141930.1, AC105450.1			ENSG00000283766, ENSG00000228613, ENSG00000231482	NA	NA	rs10206020-C	rs10206020	0	10206020	intron_variant	0	0.188020994657168	4e-06	5.39794000867204	(IGP3)	0.1798	[0.1-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q26.2	10	128435544	NR	AL390763.1 - LINC02667	ENSG00000234640	ENSG00000224190		115330	477266	rs10764775-C	rs10764775	0	10764775	intergenic_variant	1	0.340436585930543	6e-06	5.22184874961636	(IGP31)	0.1435	[0.081-0.206] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10q26.12	10	120062026	NR	NACAP2 - AL355298.1	ENSG00000180230	ENSG00000223455		64317	7954	rs17621444-C	rs17621444	0	17621444	intergenic_variant	1	0.722329589937667	3e-06	5.52287874528034	(IGP31)	0.164	[0.095-0.233] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q25.3	1	181686616	NR	CACNA1E			ENSG00000198216	NA	NA	rs3845441-C	rs3845441	0	3845441	intron_variant	0	0.127711492920748	7e-06	5.15490195998574	(IGP31)	0.2083	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p14.2	7	37027790	NR	ELMO1			ENSG00000155849	NA	NA	rs10488029-G	rs10488029	0	10488029	intron_variant	0	0.10578790637539	4e-06	5.39794000867204	(IGP35)	0.2329	[0.13-0.33] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q12.1	22	26645319	NR	ISCA2P1			ENSG00000226912	NA	NA	rs16982515-C	rs16982515	0	16982515	non_coding_transcript_exon_variant	0	0.919024750334374	3e-06	5.52287874528034	(IGP35)	0.3117	[0.18-0.44] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	21q22.11	21	32890379	NR	C21orf62-AS1			ENSG00000205930	NA	NA	rs2833991-C	rs2833991	0	2833991	intron_variant	0	0.0446738709390298	5e-06	5.30102999566398	(IGP14)	0.3471	[0.2-0.5] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q11.2	15	23572574	NR	MKRN3			ENSG00000179455	NA	NA	rs2900-G	rs2900	0	2900	intron_variant	0	0.860145730752114	4e-06	5.39794000867204	(IGP14)	0.2021	[0.12-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p36.12	1	22247449	NR	AL445253.1 - MIR4418	ENSG00000285873	ENSG00000266564		90048	18790	rs909814-C	rs909814	0	909814	intergenic_variant	1	0.57460965776591	7e-06	5.15490195998574	(IGP14)	0.1421	[0.08-0.204] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	81244914	NR	SLC38A10			ENSG00000157637	NA	NA	rs2659005-C	rs2659005	0	2659005	3_prime_UTR_variant	0	0.517323975066785	4e-07	6.39794000867204	(IGP26)	0.1653	[0.1-0.23] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	18q22.3	18	75185206	NR	AC015819.5 - ZADH2	ENSG00000285915	ENSG00000180011		59641	9907	rs9948784-G	rs9948784	0	9948784	regulatory_region_variant	1	0.9873229	2e-06	5.69897000433602	(IGP41)	1.7711	[1.04-2.5] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32759026	HLA-DQA2, HLA-DQB2	HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2, HLA-DQB2			ENSG00000232629, ENSG00000230675, ENSG00000224305, ENSG00000228813, ENSG00000196610, ENSG00000229493, ENSG00000228254, ENSG00000226165	NA	NA	rs1049110-C	rs1049110	0	1049110	missense_variant	0	0.346381764494382	2e-08	7.69897000433602	(IGP42)	0.1909	[0.12-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.2	14	99279937	NR	BCL11B - AL132819.1	ENSG00000127152	ENSG00000258383		7740	44862	rs2614463-T	rs2614463	0	2614463	intergenic_variant	1	0.396310788487282	7e-06	5.15490195998574	(IGP39)	0.1731	[0.098-0.249] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.63954583935743	1e-06	6	(IGP39)	0.1562	[0.093-0.22] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1q23.3	1	161856825	NR	ATF6			ENSG00000118217	NA	NA	rs3767633-T	rs3767633	0	3767633	intron_variant	0	0.145416417670683	8e-06	5.09691001300806	(IGP39)	0.2053	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39576157	NR	CACNA1I			ENSG00000100346	NA	NA	rs3788556-C	rs3788556	0	3788556	intron_variant	0	0.56038034270415	5e-08	7.30102999566398	(IGP39)	0.1799	[0.12-0.24] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.298476014725569	9e-24	23.0457574905607	(IGP39)	0.3388	[0.27-0.4] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.11	14	89760907	NR	AL137230.2			ENSG00000259053	NA	NA	rs2093746-C	rs2093746	0	2093746	intron_variant	0	0.265059655250113	3e-07	6.52287874528034	(IGP4)	0.2878	[0.18-0.4] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q25.1	15	79241030	NR	ANKRD34C-AS1			ENSG00000259234	NA	NA	rs4779031-C	rs4779031	0	4779031	intron_variant	0	0.211701583145561	2e-06	5.69897000433602	(IGP4)	0.1832	[0.11-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.2	3	153760634	NR	LINC02006			ENSG00000238755	NA	NA	rs6794649-C	rs6794649	0	6794649	intron_variant	0	0.159420807120324	1e-06	6	(IGP4)	0.2074	[0.12-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33128023	NR	B4GALT1			ENSG00000086062	NA	NA	rs10813951-G	rs10813951	0	10813951	intron_variant	0	0.262743396083667	5e-10	9.30102999566398	(IGP40)	0.2193	[0.15-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q32	9	112925455	NR	SLC46A2 - ZNF883	ENSG00000119457	ENSG00000285447		34579	71665	rs10817408-C	rs10817408	0	10817408	regulatory_region_variant	1	0.149460512683578	7e-06	5.15490195998574	(IGP40)	0.2234	[0.13-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q11.22	7	69773172	NR	AUTS2			ENSG00000158321	NA	NA	rs11765886-C	rs11765886	0	11765886	intron_variant	0	0.66506290565198	5e-06	5.30102999566398	(IGP40)	0.1591	[0.091-0.228] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q12.3	22	32387917	NR	RTCB			ENSG00000100220	NA	NA	rs12530-C	rs12530	0	12530	3_prime_UTR_variant	0	0.18432396929239	3e-06	5.52287874528034	(IGP40)	0.1828	[0.11-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	10p13	10	13488217	NR	BEND7			ENSG00000165626	NA	NA	rs17153352-T	rs17153352	0	17153352	intron_variant	0	0.822655938139742	7e-06	5.15490195998574	(IGP40)	0.2041	[0.12-0.29] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q32.2	14	99275850	NR	BCL11B - AL132819.1	ENSG00000127152	ENSG00000258383		3653	48949	rs2664299-C	rs2664299	0	2664299	intergenic_variant	1	0.404780828660436	9e-06	5.04575749056067	(IGP40)	0.1673	[0.094-0.241] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p12.1	20	17848636	NR	BANF2 - AL035045.1	ENSG00000125888	ENSG00000233625		112765	38727	rs2745851-G	rs2745851	0	2745851	intergenic_variant	1	0.639172889630619	4e-06	5.39794000867204	(IGP40)	0.1483	[0.085-0.212] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p25.3	3	11191093	NR	HRH1			ENSG00000196639	NA	NA	rs4684059-C	rs4684059	0	4684059	intron_variant	0	0.369267114374722	8e-06	5.09691001300806	(IGP40)	0.1691	[0.095-0.243] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q23.3	14	65308977	FUT8	AL355076.2			ENSG00000258760	NA	NA	rs11847263-G	rs11847263	0	11847263	intron_variant	0	0.391757509628303	7e-14	13.1549019599857	(IGP11)	0.2381	[0.18-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q23.3	12	108483764	NR	LINC01498			ENSG00000247213	NA	NA	rs918304-C	rs918304	0	918304	intron_variant	0	0.00963820126262628	9e-06	5.04575749056067	(IGP13)	1.5827	[0.88-2.28] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q22.3	5	115803051	NR	RNU2-49P - CDO1	ENSG00000222598	ENSG00000129596		28549	1682	rs13174348-G	rs13174348	0	13174348	intergenic_variant	1	0.784686077436582	3e-06	5.52287874528034	(IGP14)	0.1823	[0.11-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p26.2	3	3190154	NR	CRBN - AC034195.1	ENSG00000113851	ENSG00000223727		10427	60533	rs1672743-T	rs1672743	0	1672743	intergenic_variant	1	0.053157	6e-06	5.22184874961636	(IGP16)	1.1657	[0.66-1.67] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q15	5	96151236	NR	MIR583HG, AC104123.1			ENSG00000250551, ENSG00000251314	NA	NA	rs4869266-G	rs4869266	0	4869266	intron_variant	0	0.664911823953174	3e-06	5.52287874528034	(IGP16)	0.1519	[0.088-0.216] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q12	14	29618932	NR	PRKD1			ENSG00000184304	NA	NA	rs12431702-C	rs12431702	0	12431702	intron_variant	0	0.380447777481086	8e-06	5.09691001300806	(IGP17)	0.1459	[0.082-0.21] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	56027067	IL6ST, ANKRD55	AC008892.1			ENSG00000249236	NA	NA	rs17348299-C	rs17348299	0	17348299	intron_variant	0	0.836731980863373	2e-07	6.69897000433602	(IGP17)	0.2309	[0.14-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7q31.1	7	114101050	NR	FOXP2			ENSG00000128573	NA	NA	rs6466479-G	rs6466479	0	6466479	intron_variant	0	0.12247588824577	2e-06	5.69897000433602	(IGP26)	0.23	[0.14-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q22.1	4	91996064	NR	AC093810.1 - PMPCAP1	ENSG00000249052	ENSG00000248817		91729	186413	rs6853847-C	rs6853847	0	6853847	intergenic_variant	1	0.0304378588601959	5e-06	5.30102999566398	(IGP26)	0.4557	[0.26-0.65] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17p12	17	11346902	NR	SHISA6			ENSG00000188803	NA	NA	rs8076431-C	rs8076431	0	8076431	intron_variant	0	0.851273368210151	2e-06	5.69897000433602	(IGP26)	0.2132	[0.12-0.3] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q33.3	5	157388755	NR	AC008676.3, CYFIP2			ENSG00000285868, ENSG00000055163	NA	NA	rs871012-C	rs871012	0	871012	intron_variant	0	0.44603092920748	5e-06	5.30102999566398	(IGP26)	0.1473	[0.084-0.21] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.22	8	131318469	NR	AC104257.1 - SNORA72	ENSG00000253507	ENSG00000207249		837	114307	rs10108033-C	rs10108033	0	10108033	intergenic_variant	1	0.990183	1e-06	6	(IGP27)	2.9565	[1.76-4.15] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11p15.4	11	5666794	NR	TRIM5, AC104389.5			ENSG00000132256, ENSG00000239920	NA	NA	rs11820502-C	rs11820502	0	11820502	intron_variant	0	0.287504188780053	3e-06	5.52287874528034	(IGP27)	0.1762	[0.1-0.25] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q14.1	12	61155300	NR	AC090022.2 - AC090017.1	ENSG00000257865	ENSG00000257308		736007	75859	rs17124610-C	rs17124610	0	17124610	intergenic_variant	1	0.983922182991986	8e-06	5.09691001300806	(IGP27)	0.6724	[0.38-0.97] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q12	20	40849893	NR	AL035665.2 - RNA5SP484	ENSG00000286972	ENSG00000238908		91257	4226	rs6102185-G	rs6102185	0	6102185	intergenic_variant	1	0.423097751558326	1e-06	6	(IGP27)	0.151	[0.09-0.212] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20p11.23	20	20653462	NR	RALGAPA2			ENSG00000188559	NA	NA	rs6132333-C	rs6132333	0	6132333	intron_variant	0	0.0250725390917186	5e-06	5.30102999566398	(IGP27)	0.5005	[0.29-0.72] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	32422692	NR	ACO1			ENSG00000122729	NA	NA	rs7032871-T	rs7032871	0	7032871	intron_variant	0	0.278857772929653	5e-06	5.30102999566398	(IGP27)	0.1579	[0.09-0.226] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q25.2	3	153632327	NR	LINC02006			ENSG00000238755	NA	NA	rs7623788-G	rs7623788	0	7623788	intron_variant	0	0.134195012466607	5e-06	5.30102999566398	(IGP27)	0.2057	[0.12-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p31.1	1	70977467	NR	PTGER3			ENSG00000050628	NA	NA	rs909848-C	rs909848	0	909848	intron_variant	0	0.60707254318789	7e-06	5.15490195998574	(IGP27)	0.1434	[0.081-0.206] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.69898246345811	9e-37	36.0457574905607	(IGP28)	0.4436	[0.37-0.51] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p21.31	3	44291832	NR	TOPAZ1			ENSG00000173769	NA	NA	rs13323323-G	rs13323323	0	13323323	intron_variant	0	0.732786566399287	4e-06	5.39794000867204	(IGP28)	0.1593	[0.091-0.227] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	80086944	NR	CCDC40			ENSG00000141519	NA	NA	rs1467979-C	rs1467979	0	1467979	non_coding_transcript_exon_variant	0	0.823196467468806	3e-06	5.52287874528034	(IGP28)	0.186	[0.11-0.26] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q24.12	8	121170070	NR	AC068413.1 - RPL35AP19	ENSG00000253619	ENSG00000239872		50316	210067	rs1604897-C	rs1604897	0	1604897	intergenic_variant	1	0.836453155525847	8e-06	5.09691001300806	(IGP28)	0.1864	[0.1-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q23.1	8	107269199	NR	ANGPT1			ENSG00000154188	NA	NA	rs6993449-C	rs6993449	0	6993449	intron_variant	0	0.650415290106952	3e-06	5.52287874528034	(IGP28)	0.1528	[0.088-0.217] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.176683507130125	2e-20	19.698970004336	(IGP28)	0.4042	[0.32-0.49] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	15q23	15	68426648	NR	ITGA11			ENSG00000137809	NA	NA	rs16952065-C	rs16952065	0	16952065	intron_variant	0	0.937426751336898	1e-06	6	(IGP28)	0.4401	[0.26-0.62] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12q12	12	40959947	NR	CNTN1			ENSG00000018236	NA	NA	rs13328933-C	rs13328933	0	13328933	intron_variant	0	0.948348054342984	5e-06	5.30102999566398	(IGP29)	0.3116	[0.18-0.45] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	17q25.3	17	81244914	NR	SLC38A10			ENSG00000157637	NA	NA	rs2659005-C	rs2659005	0	2659005	3_prime_UTR_variant	0	0.517261684187082	9e-06	5.04575749056067	(IGP29)	0.1441	[0.08-0.208] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	20q13.2	20	54084754	NR	BCAS1 - CYP24A1	ENSG00000064787	ENSG00000019186		14160	68692	rs6064045-C	rs6064045	0	6064045	intergenic_variant	1	0.521164665033408	7e-06	5.15490195998574	(IGP29)	0.137	[0.077-0.197] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	11q22.3	11	109022640	NR	AP003123.1			ENSG00000255528	NA	NA	rs7101378-G	rs7101378	0	7101378	intron_variant	0	0.531881765256125	7e-06	5.15490195998574	(IGP29)	0.1398	[0.079-0.201] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	13q13.1	13	32136383	NR	FRY			ENSG00000073910	NA	NA	rs7331540-C	rs7331540	0	7331540	intron_variant	0	0.442209461024499	5e-06	5.30102999566398	(IGP29)	0.1407	[0.08-0.201] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3q27.3	3	187005156	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs7652995-G	rs7652995	0	7652995	intron_variant	0	0.17684106013363	3e-40	39.5228787452803	(IGP29)	0.5797	[0.49-0.67] unit increase	Illumina [~ 2500000] (imputed)	N
2009-09-28	17767157	Weedon MN	2007-09-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17767157	A common variant of HMGA2 is associated with adult and childhood height in the general population.	Height	4,921 European ancestry individuals	19,064 European ancestry adult individuals, 6,827 European ancestry children	12q14.3	12	65964567	HMGA2	HMGA2			ENSG00000149948	NA	NA	rs1042725-C	rs1042725	0	1042725	3_prime_UTR_variant	0	0.51	6e-16	15.2218487496164		0.4	[NR] cm increase	Affymetrix [364301]	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9p21.1	9	33124874	B4GALT1	B4GALT1			ENSG00000086062	NA	NA	rs12342831-C	rs12342831	0	12342831	intron_variant	0	0.262517807212823	5e-07	6.30102999566398	(IGP3)	0.1777	[0.11-0.25] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q32	5	148223504	NR	MARCOL, AC011346.1			ENSG00000248109, ENSG00000247199	NA	NA	rs1368304-G	rs1368304	0	1368304	intron_variant	0	0.915930538379341	9e-06	5.04575749056067	(IGP3)	0.2439	[0.14-0.35] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	5q11.2	5	58786896	NR	AC016642.1, RAB3C			ENSG00000248475, ENSG00000152932	NA	NA	rs10065350-C	rs10065350	0	10065350	intron_variant	0	0.841900657231865	9e-06	5.04575749056067	(IGP67)	0.2004	[0.11-0.29] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	1p36.11	1	25076133	NR	AL050344.1			ENSG00000233755	NA	NA	rs10903027-C	rs10903027	0	10903027	intron_variant	0	0.707795287049399	5e-06	5.30102999566398	(IGP67)	0.1594	[0.091-0.228] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	3p13	3	72460120	NR	RYBP - AC104435.2	ENSG00000281766	ENSG00000244345		13499	44686	rs11128271-C	rs11128271	0	11128271	intergenic_variant	1	0.93627697952826	6e-07	6.22184874961636	(IGP67)	0.338	[0.21-0.47] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q14.3	2	124499159	NR	CNTNAP5			ENSG00000155052	NA	NA	rs11899928-C	rs11899928	0	11899928	intron_variant	0	0.0215231680017802	3e-06	5.52287874528034	(IGP67)	0.7169	[0.42-1.02] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6q27	6	167341487	NR	TTLL2			ENSG00000120440	NA	NA	rs12528714-G	rs12528714	0	12528714	missense_variant	0	0.991049	8e-06	5.09691001300806	(IGP67)	2.4277	[1.36-3.49] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	6p21.32	6	32948074	NR	AL645941.2			ENSG00000248993	NA	NA	rs16871226-G	rs16871226	0	16871226	intron_variant	0	0.0244821228239845	2e-06	5.69897000433602	(IGP67)	0.5182	[0.3-0.73] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-G	rs2186369	0	2186369	intron_variant	0	0.189496820649755	1e-12	12	(IGP67)	0.2938	[0.21-0.38] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	16q24.1	16	86647390	NR	AC009154.1			ENSG00000261161	NA	NA	rs300032-G	rs300032	0	300032	intron_variant	0	0.146183376056965	3e-07	6.52287874528034	(IGP67)	0.2336	[0.14-0.32] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	22q13.1	22	39439582	NR	TAB1 - MGAT3	ENSG00000100324	ENSG00000128268		2522	17430	rs4821897-G	rs4821897	0	4821897	regulatory_region_variant	1	0.707166482866044	4e-18	17.397940008672	(IGP67)	0.2976	[0.23-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	14q24.2	14	70153925	NR	SLC8A3			ENSG00000100678	NA	NA	rs4899329-C	rs4899329	0	4899329	intron_variant	0	0.399541382287494	5e-06	5.30102999566398	(IGP67)	0.142	[0.081-0.203] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	7p12.2	7	50315611	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs6421315-C	rs6421315	0	6421315	intron_variant	0	0.368179075211393	7e-11	10.1549019599857	(IGP67)	0.2096	[0.15-0.27] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	12p13.31	12	9394366	NR	LINC02367			ENSG00000260423	NA	NA	rs7397814-C	rs7397814	0	7397814	intron_variant	0	0.791488588340009	4e-06	5.39794000867204	(IGP67)	0.188	[0.11-0.27] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	9q34.2	9	133813958	NR	VAV2			ENSG00000160293	NA	NA	rs756777-G	rs756777	0	756777	intron_variant	0	0.208834557187361	1e-06	6	(IGP67)	0.1868	[0.11-0.26] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	8q13.1	8	65711997	NR	MTFR1			ENSG00000066855	NA	NA	rs10504390-G	rs10504390	0	10504390	intron_variant	0	0.0802926317898486	8e-06	5.09691001300806	(IGP68)	0.2503	[0.14-0.36] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	4q25	4	109976429	NR	EGF			ENSG00000138798	NA	NA	rs11568995-G	rs11568995	0	11568995	intron_variant	0	0.9883953	1e-06	6	(IGP68)	1.7191	[1.02-2.41] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	2,247 European ancestry individuals	NA	2q23.3	2	152580056	NR	FMNL2			ENSG00000157827	NA	NA	rs11675841-C	rs11675841	0	11675841	intron_variant	0	0.607171814781834	8e-06	5.09691001300806	(IGP68)	0.1429	[0.08-0.206] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals	NA	3q27.3	3	187008099	ST6GAL1	ST6GAL1			ENSG00000073849	NA	NA	rs11710456-G	rs11710456	0	11710456	intron_variant	0	0.6936	8e-07	6.09691001300806	(IgG1G2)	0.044	[0.027-0.061] unit decrease	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals	NA	9p21.1	9	33124874	B4GALT1	B4GALT1			ENSG00000086062	NA	NA	rs12342831-T	rs12342831	0	12342831	intron_variant	0	0.73755	5e-08	7.30102999566398	(IgG1G2)	0.0496	[0.032-0.068] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.29096	3e-08	7.52287874528034	(IgG1G0N)	0.083	[0.054-0.112] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals	NA	22q11.23	22	23828809	SMARCB1, DERL3	SMARCB1, SMARCB1			ENSG00000099956, ENSG00000275837	NA	NA	rs2186369-T	rs2186369	0	2186369	intron_variant	0	0.81823	2e-07	6.69897000433602	(IgG1G1N)	0.0667	[0.042-0.092] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.29096	2e-10	9.69897000433602	(IgG1G1N)	0.0721	[0.050-0.094] unit increase	Illumina [~ 2500000] (imputed)	N
2013-06-14	23382691	Lauc G	2013-01-31	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/23382691	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	IgG glycosylation	1,848 European ancestry individuals	NA	22q13.1	22	39463164	MGAT3, TAB1, CACNA1I, SYNGR1	MGAT3			ENSG00000128268	NA	NA	rs909674-C	rs909674	0	909674	intron_variant	0	0.29096	9e-06	5.04575749056067	(IgG1G2N)	0.0651	[0.036-0.094] unit increase	Illumina [~ 2500000] (imputed)	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (hippocampal volume)	162 European ancestry Alzheimer's disease cases, 343 European ancestry amnestic mild cognitive impairment cases, 193 European ancestry healthy elderly controls	NA	1p22.2	1	90074206	ZNF326	AL161797.1 - AC098656.1	ENSG00000287015	ENSG00000287406		27097	167882	rs2813746-C	rs2813746	0	2813746	intergenic_variant	1	0.46	2e-06	5.69897000433602		148.1	[NR] unit increase	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (hippocampal volume)	162 European ancestry Alzheimer's disease cases, 343 European ancestry amnestic mild cognitive impairment cases, 193 European ancestry healthy elderly controls	NA	10p12.31	10	18871100	intergenic	AL512641.1 - AL357520.1	ENSG00000234244	ENSG00000234813		122758	69401	rs16917919-A	rs16917919	0	16917919	intergenic_variant	1	0.37	8e-06	5.09691001300806		147.6	[NR] unit increase	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (hippocampal volume)	162 European ancestry Alzheimer's disease cases, 343 European ancestry amnestic mild cognitive impairment cases, 193 European ancestry healthy elderly controls	NA	12q23.2	12	101293265	UTP20	UTP20			ENSG00000120800	NA	NA	rs2290720-G	rs2290720	0	2290720	intron_variant	0	0.43	3e-06	5.52287874528034		148.1	[NR] unit decrease	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (hippocampal volume)	162 European ancestry Alzheimer's disease cases, 343 European ancestry amnestic mild cognitive impairment cases, 193 European ancestry healthy elderly controls	NA	16q21	16	59856794	intergenic	LINC02141			ENSG00000261807	NA	NA	rs8056650-G	rs8056650	0	8056650	intron_variant	0	0.07	1e-06	6		302.5	[NR] unit decrease	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (temporal lobe volume)	173 European ancestry Alzheimer's disease cases, 361 European ancestry Mild Cognitive Impairment cases, 208 European ancestry controls	NA	3p22.1	3	39708102	intergenic	NFU1P1 - MYRIP	ENSG00000230757	ENSG00000170011		63397	100812	rs9832461-A	rs9832461	0	9832461	regulatory_region_variant	1	0.24	4e-06	5.39794000867204		3785.6	[NR] unit increase	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (temporal lobe volume)	173 European ancestry Alzheimer's disease cases, 361 European ancestry Mild Cognitive Impairment cases, 208 European ancestry controls	NA	4p15.1	4	33078033	intergenic	AC017013.1 - AC093606.1	ENSG00000250076	ENSG00000287968		66287	72293	rs1448284-T	rs1448284	0	1448284	intergenic_variant	1	0.03	2e-06	5.69897000433602		9939.9	[NR] unit increase	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (temporal lobe volume)	173 European ancestry Alzheimer's disease cases, 361 European ancestry Mild Cognitive Impairment cases, 208 European ancestry controls	NA	12p13.1	12	13770394	GRIN2B	GRIN2B			ENSG00000273079	NA	NA	rs11055612-C	rs11055612	0	11055612	intron_variant	0	0.5	3e-06	5.52287874528034		3371.6	[NR] unit decrease	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (temporal lobe volume)	173 European ancestry Alzheimer's disease cases, 361 European ancestry Mild Cognitive Impairment cases, 208 European ancestry controls	NA	14q24.3	14	78308963	KIAA0743	NRXN3			ENSG00000021645	NA	NA	rs7155434-A	rs7155434	0	7155434	intron_variant	0	0.27	8e-06	5.09691001300806		3643	[NR] unit increase	Illumina [546314]	N
2013-09-27	20197096	Stein JL	2010-03-01	Neuroimage	www.ncbi.nlm.nih.gov/pubmed/20197096	Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease.	Brain structure (temporal lobe volume)	173 European ancestry Alzheimer's disease cases, 361 European ancestry Mild Cognitive Impairment cases, 208 European ancestry controls	NA	15q22.2	15	62395140	intergenic	TLN2			ENSG00000171914	NA	NA	rs2456930-G	rs2456930	0	2456930	intron_variant	0	0.38	3e-07	6.52287874528034		3843.9	[NR] unit increase	Illumina [546314]	N
2010-07-12	20543847	Turnbull C	2010-06-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20543847	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.	Testicular germ cell cancer	979 European ancestry cases, 4,947 European ancestry controls	664 European ancestry cases, 3,456 European ancestry controls	5q31.3	5	142302223	SPRY4	AC091825.3 - SPRY4	ENSG00000280047	ENSG00000187678		133836	8204	rs4624820-?	rs4624820	0	4624820	regulatory_region_variant	1	0.54	1e-14	14		1.47	[1.33-1.64]	Illumina [298782]	N
2010-07-12	20543847	Turnbull C	2010-06-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20543847	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.	Testicular germ cell cancer	979 European ancestry cases, 4,947 European ancestry controls	664 European ancestry cases, 3,456 European ancestry controls	12q21.32	12	88559784	KITLG	KITLG			ENSG00000049130	NA	NA	rs3782181-?	rs3782181	0	3782181	intron_variant	0	0.78	2e-26	25.698970004336		2.22	[1.89-2.56]	Illumina [298782]	N
2010-07-12	20543847	Turnbull C	2010-06-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20543847	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.	Testicular germ cell cancer	979 European ancestry cases, 4,947 European ancestry controls	664 European ancestry cases, 3,456 European ancestry controls	5p15.33	5	1286401	TERT	TERT			ENSG00000164362	NA	NA	rs2736100-T	rs2736100	0	2736100	3_prime_UTR_variant	0	0.49	8e-15	14.0969100130081		1.33	[1.18-1.50]	Illumina [298782]	N
2010-07-12	20543847	Turnbull C	2010-06-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20543847	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.	Testicular germ cell cancer	979 European ancestry cases, 4,947 European ancestry controls	664 European ancestry cases, 3,456 European ancestry controls	5p15.33	5	1308437	TERT, CLPTM1L	TERT - MIR4457	ENSG00000164362	ENSG00000263670		13390	873	rs4635969-T	rs4635969	0	4635969	intergenic_variant	1	0.19	1e-23	23		1.54	[1.33-1.79]	Illumina [298782]	N
2010-07-12	20543847	Turnbull C	2010-06-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20543847	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.	Testicular germ cell cancer	979 European ancestry cases, 4,947 European ancestry controls	664 European ancestry cases, 3,456 European ancestry controls	9p24.3	9	863635	DMRT1	DMRT1			ENSG00000137090	NA	NA	rs755383-T	rs755383	0	755383	intron_variant	0	0.62	1e-23	23		1.37	[1.21-1.55]	Illumina [298782]	N
2010-07-12	20543847	Turnbull C	2010-06-13	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20543847	Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.	Testicular germ cell cancer	979 European ancestry cases, 4,947 European ancestry controls	664 European ancestry cases, 3,456 European ancestry controls	12p13.1	12	14500933	ATF7IP	ATF7IP			ENSG00000171681	NA	NA	rs2900333-C	rs2900333	0	2900333	3_prime_UTR_variant	0	0.62	6e-10	9.22184874961636		1.27	[1.12-1.44]	Illumina [298782]	N
2013-09-28	23665963	Dubinsky MC	2013-05-09	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/23665963	Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.	Crohn's disease (time to surgery)	983 European ancestry cases	NA	16q23.1	16	75133681	LDHD, BCAR1, ZHP1, CTRB1/2, ZNRF1	AC099508.2			ENSG00000261058	NA	NA	rs7195303-G	rs7195303	0	7195303	intron_variant	0	NR	9e-06	5.04575749056067		2.1	[1.5-2.8]	Illumina [484724]	N
2013-09-28	23665963	Dubinsky MC	2013-05-09	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/23665963	Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.	Crohn's disease (need for surgery)	239 European ancestry cases that required surgery within 5 year, 375 European ancestry cases that did not require surgery within 5 years	NA	9q34.3	9	134614732	COL5A1, RXRA	AL669970.2 - COL5A1	ENSG00000227150	ENSG00000130635		60835	27042	rs11103429-G	rs11103429	0	11103429	intergenic_variant	1	0.05	6e-06	5.22184874961636		3.6	[2.10-6.30]	Illumina [483359]	N
2013-09-28	23665963	Dubinsky MC	2013-05-09	Inflamm Bowel Dis	www.ncbi.nlm.nih.gov/pubmed/23665963	Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.	Crohn's disease (need for surgery)	239 European ancestry cases that required surgery within 5 year, 375 European ancestry cases that did not require surgery within 5 years	NA	7q21.11	7	82210237	CACNA2D1	CACNA2D1			ENSG00000153956	NA	NA	rs11978472-?	rs11978472	0	11978472	intron_variant	0	0.70	6e-06	5.22184874961636		2	[1.43-2.50]	Illumina [483359]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	8q24.21	8	127506309	NR	CASC8 - AC104370.1	ENSG00000246228	ENSG00000286266		24170	72164	rs4242384-?	rs4242384	0	4242384	regulatory_region_variant	1	NR	2e-24	23.698970004336		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	11q13.3	11	69228491	NR	AP003071.2 - MYEOV	ENSG00000261070	ENSG00000172927		56927	65660	rs7130881-?	rs7130881	0	7130881	intergenic_variant	1	NR	8e-13	12.0969100130081		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	6q25.3	6	160160342	NR	SLC22A1 - AL645733.1	ENSG00000175003	ENSG00000216516		1624	3197	rs651164-?	rs651164	0	651164	regulatory_region_variant	1	NR	2e-09	8.69897000433602		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	2p21	2	43326810	THADA	THADA			ENSG00000115970	NA	NA	rs1465618-?	rs1465618	0	1465618	intron_variant	0	0.23	2e-08	7.69897000433602		1.08	[1.03-1.12]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	4q22.3	4	94641726	PDLIM5	PDLIM5			ENSG00000163110	NA	NA	rs17021918-?	rs17021918	0	17021918	intron_variant	0	0.65	4e-15	14.397940008672		1.11	[1.08-1.15]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	4q24	4	105140377	TET2	AC004069.1			ENSG00000251259	NA	NA	rs7679673-?	rs7679673	0	7679673	intron_variant	0	0.55	3e-14	13.5228787452803		1.1	[1.06-1.14]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	8p21.2	8	23668950	NKX3.1	SINHCAFP3 - NKX3-1	ENSG00000253488	ENSG00000167034		33443	9747	rs1512268-?	rs1512268	0	1512268	intergenic_variant	1	0.45	3e-30	29.5228787452803		1.18	[1.14-1.22]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	11p15.5	11	2212344	IGF2, INS, TH, IGF2AS	MIR4686 - ASCL2	ENSG00000265258	ENSG00000183734		39206	56151	rs7127900-?	rs7127900	0	7127900	intergenic_variant	1	0.20	3e-33	32.5228787452803		1.22	[1.17-1.27]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	22q13.2	22	43104206	NR	AL022237.1 - BIK	ENSG00000234735	ENSG00000100290		11682	6544	rs5759167-?	rs5759167	0	5759167	TF_binding_site_variant	1	0.53	6e-29	28.2218487496164		1.16	[1.14-1.20]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	Xp11.22	X	51467205	NR	AL158055.1 - NUDT11	ENSG00000226530	ENSG00000196368		1544	22806	rs1327301-?	rs1327301	0	1327301	intergenic_variant	1	NR	2e-10	9.69897000433602		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	4q22.3	4	94593458	PDLIM5	PDLIM5			ENSG00000163110	NA	NA	rs12500426-?	rs12500426	0	12500426	intron_variant	0	0.46	1e-11	11		1.08	[1.05-1.12]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	2p15	2	63074029	EHBP1	OTX1 - AC009501.2	ENSG00000115507	ENSG00000270437		16193	8979	rs6545977-?	rs6545977	0	6545977	regulatory_region_variant	1	NR	5e-07	6.30102999566398		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	7q21.3	7	98187015	NR	LMTK2			ENSG00000164715	NA	NA	rs6465657-?	rs6465657	0	6465657	intron_variant	0	NR	2e-08	7.69897000433602		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	10q11.22	10	46070851	NR	RPL23AP61 - AGAP7P	ENSG00000280012	ENSG00000264204		7136	38770	rs3123078-?	rs3123078	0	3123078	regulatory_region_variant	1	NR	1e-19	19		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	17q12	17	37741165	NR	HNF1B, HNF1B			ENSG00000276194, ENSG00000275410	NA	NA	rs7501939-?	rs7501939	0	7501939	intron_variant	0	NR	3e-18	17.5228787452803		NA		Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	17q24.3	17	71112612	NR	CASC17			ENSG00000260785	NA	NA	rs1859962-?	rs1859962	0	1859962	intron_variant	0	NR	2e-16	15.698970004336		NA		Illumina [541129]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	1p31.3	1	67240275	IL23R	IL23R			ENSG00000162594	NA	NA	rs11209026-?	rs11209026	0	11209026	missense_variant	0	0.94	9e-14	13.0457574905607		1.89	[1.56-2.27]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	2q11.2	2	102047167	IL1R2	AC007271.1			ENSG00000287771	NA	NA	rs2310173-A	rs2310173	0	2310173	intron_variant	0	0.45	5e-07	6.30102999566398		1.18	[1.10-1.27]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	21q22.2	21	39093252	PSMG1	AF064858.1 - RPL23AP12	ENSG00000235888	ENSG00000228861		30358	34316	rs2242944-?	rs2242944	0	2242944	intergenic_variant	1	0.63	8e-20	19.0969100130081		1.39	[1.28-1.49]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	2p15	2	62324337	B3GNT2	RN7SL51P - AC093159.2	ENSG00000239958	ENSG00000270335		61666	24611	rs10865331-A	rs10865331	0	10865331	intergenic_variant	1	0.40	2e-19	18.698970004336		1.27	[1.18-1.37]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	5q15	5	96793809	ERAP1	ERAP1			ENSG00000164307	NA	NA	rs27434-A	rs27434	0	27434	synonymous_variant	0	0.23	5e-12	11.301029995664		1.19	[1.10-1.30]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	6p21.33	6	31368323	MHC	AL671883.3			ENSG00000285647	NA	NA	rs7743761-?	rs7743761	0	7743761	intron_variant	0	NR	5e-304	303.301029995664		NA		Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	2q31.3	2	181143073	NR	LINC01934			ENSG00000234663	NA	NA	rs1018326-C	rs1018326	0	1018326	intron_variant	0	0.45	2e-06	5.69897000433602		1.24	[1.15-1.33]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	10p12.31	10	19640584	NR	MALRD1			ENSG00000204740	NA	NA	rs1326986-C	rs1326986	0	1326986	intron_variant	0	0.05	4e-06	5.39794000867204		1.9	[1.58-2.29]	Illumina [288662]	N
2010-02-02	20062062	Reveille JD	2010-01-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20062062	Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.	Ankylosing spondylitis	2,053 European ancestry cases, 5,140 European ancestry controls	898 European ancestry cases, 1,518 European ancestry controls	4q21.21	4	80028675	ANTXR2	ANTXR2			ENSG00000163297	NA	NA	rs4333130-?	rs4333130	0	4333130	intron_variant	0	0.64	9e-08	7.04575749056067		1.22	[1.12-1.32]	Illumina [288662]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	7p15.3	7	20954872	NR	LINC01162			ENSG00000232790	NA	NA	rs12155172-?	rs12155172	0	12155172	intron_variant	0	0.20	9e-06	5.04575749056067		1.05	[1.00-1.10]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	2q31.1	2	172446825	ITGA6	ITGA6			ENSG00000091409	NA	NA	rs12621278-?	rs12621278	0	12621278	intron_variant	0	0.94	9e-23	22.0457574905607		1.33	[1.25-1.43]	Illumina [541129]	N
2009-12-29	19767753	Eeles RA	2009-09-20	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19767753	Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.	Prostate cancer	1,854 European ancestry cases, 1,894 European ancestry controls	19,879 cases and 18,761 controls of European, East Asian, African American, Latino, and Hawaiian ancestry	3p11.2	3	87124174	NR	AC107204.1			ENSG00000281392	NA	NA	rs17181170-?	rs17181170	0	17181170	intron_variant	0	NR	3e-08	7.52287874528034		NA		Illumina [541129]	N
2008-08-21	17767159	Menzel S	2007-09-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17767159	A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.	F-cell distribution	179 European ancestry individuals	90 European ancestry individuals	6q23.3	6	135097880	intergenic	HBS1L			ENSG00000112339	NA	NA	rs9399137-?	rs9399137	0	9399137	intron_variant	0	0.23	3e-36	35.5228787452803		15.8	[NR] % variance	Illumina [308015]	N
2008-08-21	17767159	Menzel S	2007-09-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17767159	A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.	F-cell distribution	179 European ancestry individuals	90 European ancestry individuals	2p16.1	2	60490908	BCL11A	BCL11A			ENSG00000119866	NA	NA	rs1427407-?	rs1427407	0	1427407	intron_variant	0	0.14	6e-31	30.2218487496164		13.1	[NR] % variance	Illumina [308015]	N
2008-08-21	17767159	Menzel S	2007-09-02	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17767159	A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15.	F-cell distribution	179 European ancestry individuals	90 European ancestry individuals				HBB					NA	NA	Chr11:5232745-?	Chr11:5232745	0	NA		1	0.33	2e-38	37.698970004336		10.2	[NR] % variance	Illumina [308015]	N
2011-04-13	21396408	Miller EK	2011-03-25	Vaccine	www.ncbi.nlm.nih.gov/pubmed/21396408	Atopy history and the genomics of wheezing after influenza vaccination in children 6-59 months of age.	Vaccine-related adverse events	6 European ancestry cases,55 European ancestry controls	NA	1q23.2	1	159740727	intergenic	CRP - AL445528.1	ENSG00000132693	ENSG00000235226		26138	18443	rs11265263-?	rs11265263	0	11265263	intergenic_variant	1	0.04	3e-06	5.52287874528034	(wheezing)	NA		Illumina [468458]	N
2011-04-13	21396408	Miller EK	2011-03-25	Vaccine	www.ncbi.nlm.nih.gov/pubmed/21396408	Atopy history and the genomics of wheezing after influenza vaccination in children 6-59 months of age.	Vaccine-related adverse events	6 European ancestry cases,55 European ancestry controls	NA	7p11.2	7	54114239	intergenic	LINC02854 - AC092848.2	ENSG00000238131	ENSG00000287953		166435	70832	rs6593122-?	rs6593122	0	6593122	intergenic_variant	1	0.11	4e-06	5.39794000867204	(influenza)	NA		Illumina [468458]	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	1p34.3	1	36106319	COL8A2	COL8A2			ENSG00000171812	NA	NA	rs96067-A	rs96067	0	96067	intron_variant	0	0.8	3e-11	10.5228787452803		0.03	[-0.0092-0.0692] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	2q36.3	2	227270464	COL4A3	AC097662.1, COL4A3			ENSG00000236432, ENSG00000169031	NA	NA	rs7606754-A	rs7606754	0	7606754	intron_variant	0	0.35	1e-09	9		0.07	[0.05-0.09] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	3q26.31	3	172277815	FNDC3B	FNDC3B			ENSG00000075420	NA	NA	rs4894535-T	rs4894535	0	4894535	intron_variant	0	0.17	5e-12	11.301029995664		0.1	[0.061-0.139] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	3q26.32	3	177586510	TBL1XR1, KCNMB2	LINC00578			ENSG00000228221	NA	NA	rs7620503-T	rs7620503	0	7620503	intron_variant	0	0.39	1e-08	8		0.06	[0.04-0.08] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	4q31.23	4	148158346	NR3C2	NR3C2, AC069272.1			ENSG00000151623, ENSG00000250354	NA	NA	rs3931397-T	rs3931397	0	3931397	intron_variant	0	0.07	4e-08	7.39794000867204		0.12	[0.061-0.179] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	5q12.3	5	65329685	ADAMTS6	ADAMTS6			ENSG00000049192	NA	NA	rs2307121-T	rs2307121	0	2307121	intron_variant	0	0.34	6e-11	10.2218487496164		0.09	[0.07-0.11] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	6q14.1	6	82084877	IBTK, FAM46A	LINC02542			ENSG00000226453	NA	NA	rs1538138-T	rs1538138	0	1538138	intron_variant	0	0.25	1e-12	12		0.07	[0.031-0.109] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	7q11.21	7	65861834	VKORC1L1	RNU6-973P - VKORC1L1	ENSG00000201560	ENSG00000196715		2068	11240	rs11763147-A	rs11763147	0	11763147	intergenic_variant	1	0.45	4e-09	8.39794000867204		0.07	[0.05-0.09] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	7q11.21	7	66956459	C7orf42	TMEM248			ENSG00000106609	NA	NA	rs4718428-T	rs4718428	0	4718428	3_prime_UTR_variant	0	0.65	3e-10	9.52287874528034		0.05	[0.03-0.07] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	9p23	9	13557492	NF1B, MPDZ	AL583785.1			ENSG00000226197	NA	NA	rs1324183-A	rs1324183	0	1324183	intron_variant	0	0.2	8e-09	8.09691001300806		0.05	[0.011-0.089] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	9q31.3	9	110900401	LPAR1	LPAR1			ENSG00000198121	NA	NA	rs1007000-T	rs1007000	0	1007000	intron_variant	0	0.22	5e-12	11.301029995664		0.07	[0.031-0.109] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	9q34.3	9	134548682	COL5A1, RXRA	AL669970.3 - AL669970.2	ENSG00000228877	ENSG00000227150		3438	4056	rs1536482-A	rs1536482	0	1536482	regulatory_region_variant	1	0.34	3e-22	21.5228787452803		0.12	[0.1-0.14] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	9q34.3	9	134676205	COL5A1	COL5A1			ENSG00000130635	NA	NA	rs7044529-T	rs7044529	0	7044529	intron_variant	0	0.15	5e-12	11.301029995664		0.13	[0.091-0.169] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	9q34.3	9	136965812	LCN12, PTGDS	LCN12 - LINC02692	ENSG00000184925	ENSG00000198454		10315	3431	rs11145951-T	rs11145951	0	11145951	intergenic_variant	1	0.49	6e-12	11.2218487496164		0.09	[0.07-0.11] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	10q21.2	10	62070527	ARID5B	ARID5B			ENSG00000150347	NA	NA	rs7090871-T	rs7090871	0	7090871	intron_variant	0	0.59	6e-10	9.22184874961636		0.06	[0.04-0.08] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	11q23.1	11	111042516	ARHGAP20, POU2AF1	RNA5SP350 - AP003973.2	ENSG00000200168	ENSG00000271390		2308	47354	rs4938174-A	rs4938174	0	4938174	intergenic_variant	1	0.31	4e-09	8.39794000867204		0.06	[0.04-0.08] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	12q23.3	12	104051964	GLT8D2	GLT8D2			ENSG00000120820	NA	NA	rs1564892-A	rs1564892	0	1564892	intron_variant	0	0.76	2e-10	9.69897000433602		0.08	[0.041-0.119] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	13q12.12	13	22654552	SGCG, FGF9	AL512484.1 - FTH1P7	ENSG00000287357	ENSG00000232187		60681	41471	rs1034200-A	rs1034200	0	1034200	intergenic_variant	1	0.23	4e-09	8.39794000867204		0.1	[0.061-0.139] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	13q14.11	13	40536747	FOXO1	FOXO1			ENSG00000150907	NA	NA	rs2721051-T	rs2721051	0	2721051	intron_variant	0	0.11	4e-14	13.397940008672		0.17	[0.13-0.21] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	15q13.1	15	29881682	TJP1	TJP1			ENSG00000104067	NA	NA	rs785422-T	rs785422	0	785422	intron_variant	0	0.11	3e-11	10.5228787452803		0.14	[0.1-0.18] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	15q22.33	15	67175169	SMAD3	SMAD3			ENSG00000166949	NA	NA	rs12913547-T	rs12913547	0	12913547	intron_variant	0	0.77	5e-10	9.30102999566398		0.08	[0.041-0.119] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	15q25.3	15	85282336	AKAP13	ADAMTS7P4			ENSG00000218052	NA	NA	rs6496932-A	rs6496932	0	6496932	intron_variant	0	0.2	7e-13	12.1549019599857		0.11	[0.071-0.149] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	15q26.3	15	101018357	LRRK1	LRRK1			ENSG00000154237	NA	NA	rs930847-T	rs930847	0	930847	intron_variant	0	0.77	6e-19	18.2218487496164		0.11	[0.071-0.149] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	15q26.3	15	101241729	CHSY1	CHSY1			ENSG00000131873	NA	NA	rs752092-A	rs752092	0	752092	intron_variant	0	0.66	2e-09	8.69897000433602		0.08	[0.06-0.1] unit decrease	Affymetrix, Illumina [~ 1000000] (imputed)	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	16q24.2	16	88298034	BANP, ZNF469	AC138512.1			ENSG00000261273	NA	NA	rs9938149-A	rs9938149	0	9938149	intron_variant	0	0.62	2e-49	48.698970004336		0.17	[0.15-0.19] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2011-04-13	21437268	McKay JD	2011-03-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21437268	A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.	Oral cavity and pharyngeal cancer	2,091 European ancestry cases, 8,334 European ancestry controls	6,574 European ancestry cases, 7,892 European ancestry controls	4q23	4	99353129	ADH1C	ADH1B - ADH7	ENSG00000196616	ENSG00000196344		369	59132	rs1789924-C	rs1789924	0	1789924	regulatory_region_variant	1	NR	3e-07	6.52287874528034		1.12	[1.07-1.17]	Illumina [294620]	N
2011-04-13	21437268	McKay JD	2011-03-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21437268	A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.	Oral cavity and pharyngeal cancer	2,091 European ancestry cases, 8,334 European ancestry controls	6,574 European ancestry cases, 7,892 European ancestry controls	4q23	4	99318162	ADH1B	ADH1B			ENSG00000196616	NA	NA	rs1229984-T	rs1229984	0	1229984	missense_variant	0	0.94	1e-20	20		1.56	[1.41-1.69]	Illumina [294620]	N
2011-04-13	21437268	McKay JD	2011-03-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21437268	A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.	Oral cavity and pharyngeal cancer	2,091 European ancestry cases, 8,334 European ancestry controls	6,574 European ancestry cases, 7,892 European ancestry controls	12q24.13	12	112083644	ALDH2	NAA25			ENSG00000111300	NA	NA	rs4767364-A	rs4767364	0	4767364	intron_variant	0	0.29	2e-08	7.69897000433602		1.13	[1.08-1.18]	Illumina [294620]	N
2011-04-13	21437268	McKay JD	2011-03-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21437268	A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.	Oral cavity and pharyngeal cancer	2,091 European ancestry cases, 8,334 European ancestry controls	6,574 European ancestry cases, 7,892 European ancestry controls	4q23	4	99420704	ADH7	ADH7			ENSG00000196344	NA	NA	rs971074-G	rs971074	0	971074	synonymous_variant	0	NR	9e-17	16.0457574905607		1.33	[1.25-1.43]	Illumina [294620]	N
2011-04-13	21437268	McKay JD	2011-03-17	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21437268	A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.	Oral cavity and pharyngeal cancer	2,091 European ancestry cases, 8,334 European ancestry controls	6,574 European ancestry cases, 7,892 European ancestry controls	4q21.23	4	83453327	HEL308, ADH, FAM175A	HELQ			ENSG00000163312	NA	NA	rs1494961-C	rs1494961	0	1494961	missense_variant	0	0.49	1e-08	8		1.12	[1.08-1.17]	Illumina [294620]	N
2011-04-29	21452313	Freudenberg J	2011-04-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/21452313	Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.	Rheumatoid arthritis	801 Korean ancestry cases, 757 Korean ancestry controls	718 Korean ancestry cases, 719 Korean ancestry controls	8p23.1	8	11502129	BLK	BLK			ENSG00000136573	NA	NA	rs1600249-?	rs1600249	0	1600249	intron_variant	0		5e-06	5.30102999566398		1.3	[1.16-1.45]	Illumina [441398]	N
2011-04-29	21452313	Freudenberg J	2011-04-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/21452313	Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.	Rheumatoid arthritis	801 Korean ancestry cases, 757 Korean ancestry controls	718 Korean ancestry cases, 719 Korean ancestry controls	3p14.3	3	56932218	ARHGEF3	ARHGEF3			ENSG00000163947	NA	NA	rs2062583-?	rs2062583	0	2062583	intron_variant	0		2e-06	5.69897000433602		1.59	[1.30-1.92]	Illumina [441398]	N
2011-04-29	21452313	Freudenberg J	2011-04-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/21452313	Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.	Rheumatoid arthritis	801 Korean ancestry cases, 757 Korean ancestry controls	718 Korean ancestry cases, 719 Korean ancestry controls	6p21.32	6	32713151	HLA-DRB1	MTCO3P1 - AL662789.1	ENSG00000237145	ENSG00000232080		6196	4854	rs7765379-?	rs7765379	0	7765379	regulatory_region_variant	1		5e-23	22.301029995664		2.51	[NR]	Illumina [441398]	N
2011-04-29	21452313	Freudenberg J	2011-04-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/21452313	Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.	Rheumatoid arthritis	801 Korean ancestry cases, 757 Korean ancestry controls	718 Korean ancestry cases, 719 Korean ancestry controls	12q21.1	12	72330254	TRHDE	TRHDE			ENSG00000072657	NA	NA	rs12831974-?	rs12831974	0	12831974	intron_variant	0		6e-06	5.22184874961636		1.27	[1.14-1.40]	Illumina [441398]	N
2011-04-29	21452313	Freudenberg J	2011-04-01	Arthritis Rheum	www.ncbi.nlm.nih.gov/pubmed/21452313	Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.	Rheumatoid arthritis	801 Korean ancestry cases, 757 Korean ancestry controls	718 Korean ancestry cases, 719 Korean ancestry controls	1p36.13	1	17348042	PADI4	PADI4, PADI4			ENSG00000159339, ENSG00000280908	NA	NA	rs2240335-?	rs2240335	0	2240335	synonymous_variant	0		2e-08	7.69897000433602		1.5	[NR]	Illumina [441398]	N
2013-03-28	23291589	Lu Y	2013-01-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/23291589	Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.	Corneal structure	13,057 European ancestry individuals, 2,538 Indian ancestry individuals, 2,542 Malay ancestry individuals, 1,883 Chinese ancestry individuals	NA	17p12	17	14657699	PMP22, HS3ST3B1	AC022816.1 - RPS18P12	ENSG00000230647	ENSG00000230897		236227	47377	rs12940030-T	rs12940030	0	12940030	intergenic_variant	1	0.71	7e-10	9.15490195998574		0.08	[0.06-0.1] unit increase	Affymetrix, Illumina [~ 1000000] (imputed)	N
2010-01-13	20037589	Illig T	2009-12-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20037589	A genome-wide perspective of genetic variation in human metabolism.	Metabolite levels	1,029 European ancestry individuals	1,202 European ancestry individuals	1p31.1	1	75640990	ACADM	SLC44A5 - AL137803.1	ENSG00000137968	ENSG00000230863		29874	188	rs211718-C	rs211718	0	211718	intergenic_variant	1	NR	1e-63	63	(C12/C10)	0.12	[NR] unit increase	Affymetrix [517480]	N
2010-01-13	20037589	Illig T	2009-12-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20037589	A genome-wide perspective of genetic variation in human metabolism.	Metabolite levels	1,029 European ancestry individuals	1,202 European ancestry individuals	4q32.1	4	158709665	ETFDH	PPID			ENSG00000171497	NA	NA	rs8396-T	rs8396	0	8396	3_prime_UTR_variant	0	NR	4e-24	23.397940008672	(C14:1-OH/C10)	0.102	[NR] unit increase	Affymetrix [517480]	N
2010-01-13	20037589	Illig T	2009-12-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20037589	A genome-wide perspective of genetic variation in human metabolism.	Metabolite levels	1,029 European ancestry individuals	1,202 European ancestry individuals	11q12.2	11	61803311	FADS1	FADS2, FADS1			ENSG00000134824, ENSG00000149485	NA	NA	rs174547-T	rs174547	0	174547	intron_variant	0	NR	7e-179	178.154901959986	(PC aa C36:3/PC aa C36:4)	0.151	[NR] unit increase	Affymetrix [517480]	N
2010-01-13	20037589	Illig T	2009-12-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20037589	A genome-wide perspective of genetic variation in human metabolism.	Metabolite levels	1,029 European ancestry individuals	1,202 European ancestry individuals	12q24.31	12	120737721	ACADS	ACADS			ENSG00000122971	NA	NA	rs2014355-T	rs2014355	0	2014355	non_coding_transcript_exon_variant	0	NR	5e-96	95.301029995664	(C3/C4)	0.218	[NR] unit decrease	Affymetrix [517480]	N
2010-01-13	20037589	Illig T	2009-12-27	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/20037589	A genome-wide perspective of genetic variation in human metabolism.	Metabolite levels	1,029 European ancestry individuals	1,202 European ancestry individuals	2q34	2	210195326	ACADL	AC006994.2, ACADL			ENSG00000279317, ENSG00000115361	NA	NA	rs2286963-T	rs2286963	0	2286963	missense_variant	0	NR	3e-60	59.5228787452803	(C9/C10:2)	0.219	[NR] unit increase	Affymetrix [517480]	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	11q14.3	11	92947847	LOC100128354	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		10181	17950	rs10830956-C	rs10830956	0	10830956	intergenic_variant	1	NR	5e-11	10.301029995664	(TG-GLUC)	0.2	[0.14-0.26] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	8p21.3	8	19968862	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		1603	110252	rs2197089-C	rs2197089	0	2197089	regulatory_region_variant	1	NR	2e-09	8.69897000433602	(TG-GLUC)	0.18	[0.12-0.24] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	6p12.3	6	50830813	TFAP2B	TFAP2B			ENSG00000008196	NA	NA	rs2206277-A	rs2206277	0	2206277	intron_variant	0	NR	1e-07	7	(WC-GLUC)	0.17	[0.11-0.23] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	8p21.3	8	20010875	LPL	LPL - AC100802.1	ENSG00000175445	ENSG00000253775		43616	68239	rs1441756-G	rs1441756	0	1441756	intergenic_variant	1	NR	3e-08	7.52287874528034	(BP-HDLC)	0.18	[0.12-0.24] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	11q14.3	11	92940662	LOC100128354	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		2996	25135	rs1387153-C	rs1387153	0	1387153	intergenic_variant	1	NR	2e-09	8.69897000433602	(HDLC-GLUC)	0.21	[0.15-0.27] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	16q13	16	56954132	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		9268	7791	rs173539-C	rs173539	0	173539	intergenic_variant	1	NR	1e-16	16	(HDLC-WC)	0.29	[0.23-0.35] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	11q23.3	11	116763146	BUD13	BUD13			ENSG00000137656	NA	NA	rs11820589-A	rs11820589	0	11820589	missense_variant	0	NR	6e-09	8.22184874961636	(TG-GLUC)	0.32	[0.20-0.44] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	16q13	16	56959412	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		14548	2511	rs3764261-G	rs3764261	0	3764261	regulatory_region_variant	1	NR	3e-13	12.5228787452803	(BP-HDLC)	0.29	[0.21-0.37] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	15q21.3	15	58388755	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs2043085-A	rs2043085	0	2043085	intron_variant	0	NR	1e-08	8	(HDLC-GLUC)	0.17	[0.11-0.23] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	8p21.3	8	19959423	LPL	LPL			ENSG00000175445	NA	NA	rs301-C	rs301	0	301	intron_variant	0	NR	3e-11	10.5228787452803	(HDLC-WC)	0.22	[0.16-0.28] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	11q23.3	11	116781491	ZNF259	ZPR1			ENSG00000109917	NA	NA	rs12286037-C	rs12286037	0	12286037	intron_variant	0	NR	1e-08	8	(TG-GLUC)	0.32	[0.20-0.44] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	11q14.3	11	92940662	LOC100128354	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		2996	25135	rs1387153-C	rs1387153	0	1387153	intergenic_variant	1	NR	8e-09	8.09691001300806	(BP-GLUC)	0.19	[0.13-0.25] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	16q13	16	56968820	CETP	CETP			ENSG00000087237	NA	NA	rs9939224-G	rs9939224	0	9939224	intron_variant	0	0.46	7e-12	11.1549019599857	(HDLC-GLUC)	0.31	[0.21-0.41] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	2q31.1	2	168926370	ABCB11	ABCB11			ENSG00000073734	NA	NA	rs569805-A	rs569805	0	569805	intron_variant	0	NR	9e-08	7.04575749056067	(HDLC-GLUC)	0.16	[0.10-0.22] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	8p23.1	8	9325848	LOC100129150	AC022784.1			ENSG00000248538	NA	NA	rs9987289-A	rs9987289	0	9987289	non_coding_transcript_exon_variant	0	NR	4e-08	7.39794000867204	(HDLC-WC)	0.24	[0.16-0.32] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome (bivariate traits)	22,161 European ancestry individuals	NA	15q21.3	15	58386313	LIPC	ALDH1A2			ENSG00000128918	NA	NA	rs10468017-C	rs10468017	0	10468017	intron_variant	0	NR	6e-08	7.22184874961636	(HDLC-WC)	0.16	[0.10-0.22] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome	22,161 European ancestry individuals	NA	11q23.3	11	116768388	BUD13	BUD13			ENSG00000137656	NA	NA	rs10790162-A	rs10790162	0	10790162	intron_variant	0	NR	5e-09	8.30102999566398		0.25	[0.17-0.33] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome	22,161 European ancestry individuals	NA	16q13	16	56954132	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		9268	7791	rs173539-C	rs173539	0	173539	intergenic_variant	1	NR	9e-09	8.04575749056067		0.16	[0.10-0.22] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome	22,161 European ancestry individuals	NA	11q23.3	11	116782580	ZNF259	ZPR1			ENSG00000109917	NA	NA	rs2075290-C	rs2075290	0	2075290	intron_variant	0	NR	2e-09	8.69897000433602		0.26	[0.18-0.34] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome	22,161 European ancestry individuals	NA	8p21.3	8	19958727	LPL	LPL			ENSG00000175445	NA	NA	rs295-A	rs295	0	295	intron_variant	0	NR	2e-09	8.69897000433602		0.17	[0.11-0.23] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Metabolic syndrome	22,161 European ancestry individuals	NA	11q23.3	11	116789970	APOA5	APOA5			ENSG00000110243	NA	NA	rs2266788-C	rs2266788	0	2266788	3_prime_UTR_variant	0	NR	2e-09	8.69897000433602		0.26	[0.18-0.34] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	2p23.3	2	27519736	GCKR	GCKR			ENSG00000084734	NA	NA	rs780093-A	rs780093	0	780093	intron_variant	0	NR	2e-12	11.698970004336		0.19	[0.13-0.25] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	2p23.3	2	27629051	CCDC121	GPN1, AC074091.2			ENSG00000198522, ENSG00000259080	NA	NA	rs3749147-C	rs3749147	0	3749147	missense_variant	0	NR	1e-09	9		0.18	[0.12-0.24] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	11q23.3	11	116789970	APOA5	APOA5			ENSG00000110243	NA	NA	rs2266788-A	rs2266788	0	2266788	3_prime_UTR_variant	0	NR	2e-16	15.698970004336		0.41	[0.31-0.51] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	2p23.3	2	27592643	ZNF512	AC074091.2, ZNF512			ENSG00000259080, ENSG00000243943	NA	NA	rs13022873-A	rs13022873	0	13022873	intron_variant	0	NR	5e-09	8.30102999566398		0.17	[0.11-0.23] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	11q23.3	11	116768388	BUD13	BUD13			ENSG00000137656	NA	NA	rs10790162-A	rs10790162	0	10790162	intron_variant	0	NR	7e-16	15.1549019599857		0.39	[0.29-0.49] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	2p23.3	2	27578892	C2orf16	C2orf16			ENSG00000221843	NA	NA	rs1919128-A	rs1919128	0	1919128	missense_variant	0	NR	2e-09	8.69897000433602		0.18	[0.12-0.24] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Waist Circumference - Triglycerides (WC-TG)	22,161 European ancestry individuals	NA	11q23.3	11	116782580	ZNF259	ZPR1			ENSG00000109917	NA	NA	rs2075290-C	rs2075290	0	2075290	intron_variant	0	NR	1e-16	16		0.41	[0.31-0.51] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	8p21.3	8	19966981	LPL	LPL			ENSG00000175445	NA	NA	rs13702-A	rs13702	0	13702	3_prime_UTR_variant	0	NR	1e-16	16		0.29	[0.23-0.35] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	16q13	16	56954132	CETP	HERPUD1 - CETP	ENSG00000051108	ENSG00000087237		9268	7791	rs173539-C	rs173539	0	173539	intergenic_variant	1	NR	5e-16	15.301029995664		0.26	[0.20-0.32] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	11q23.3	11	116789970	APOA5	APOA5			ENSG00000110243	NA	NA	rs2266788-C	rs2266788	0	2266788	3_prime_UTR_variant	0	NR	5e-13	12.301029995664		0.39	[0.29-0.49] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	11q23.3	11	116768388	BUD13	BUD13			ENSG00000137656	NA	NA	rs10790162-A	rs10790162	0	10790162	intron_variant	0	NR	3e-15	14.5228787452803		0.38	[0.28-0.48] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	8q24.13	8	125472284	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs2954026-G	rs2954026	0	2954026	intron_variant	0	NR	8e-09	8.09691001300806		0.16	[0.10-0.22] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	8p23.1	8	9325848	LOC100129150	AC022784.1			ENSG00000248538	NA	NA	rs9987289-A	rs9987289	0	9987289	non_coding_transcript_exon_variant	0	NR	1e-08	8		0.25	[0.17-0.33] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	11q23.3	11	116782580	ZNF259	ZPR1			ENSG00000109917	NA	NA	rs2075290-C	rs2075290	0	2075290	intron_variant	0	NR	2e-14	13.698970004336		0.39	[0.29-0.49] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	HDL Cholesterol - Triglycerides (HDLC-TG)	22,161 European ancestry individuals	NA	19q13.32	19	44911194	LOC100129500	AC011481.3			ENSG00000280087	NA	NA	rs439401-C	rs439401	0	439401	non_coding_transcript_exon_variant	0	NR	1e-08	8		0.24	[0.16-0.32] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Triglycerides-Blood Pressure (TG-BP)	22,161 European ancestry individuals	NA	8p21.3	8	19967156	LPL	LPL			ENSG00000175445	NA	NA	rs15285-A	rs15285	0	15285	3_prime_UTR_variant	0	NR	1e-10	10		0.27	[0.19-0.35] unit decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Triglycerides-Blood Pressure (TG-BP)	22,161 European ancestry individuals	NA	11q23.3	11	116778419	ZNF259	ZPR1			ENSG00000109917	NA	NA	rs11823543-A	rs11823543	0	11823543	3_prime_UTR_variant	0	NR	3e-09	8.52287874528034		0.35	[0.23-0.47] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Triglycerides-Blood Pressure (TG-BP)	22,161 European ancestry individuals	NA	8q24.13	8	125481504	TRIB1	AC091114.1			ENSG00000253111	NA	NA	rs2954033-A	rs2954033	0	2954033	intron_variant	0	NR	9e-09	8.04575749056067		0.17	[0.11-0.23] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Triglycerides-Blood Pressure (TG-BP)	22,161 European ancestry individuals	NA	2p23.3	2	27519736	GCKR	GCKR			ENSG00000084734	NA	NA	rs780093-A	rs780093	0	780093	intron_variant	0	NR	3e-10	9.52287874528034		0.18	[0.12-0.24] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Triglycerides-Blood Pressure (TG-BP)	22,161 European ancestry individuals	NA	11q23.3	11	116755542	BUD13	BUD13			ENSG00000137656	NA	NA	rs11825181-A	rs11825181	0	11825181	intron_variant	0	NR	3e-09	8.52287874528034		0.32	[0.22-0.42] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-04-11	21386085	Kraja AT	2011-03-08	Diabetes	www.ncbi.nlm.nih.gov/pubmed/21386085	A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.	Triglycerides-Blood Pressure (TG-BP)	22,161 European ancestry individuals	NA	11q23.3	11	116789970	APOA5	APOA5			ENSG00000110243	NA	NA	rs2266788-C	rs2266788	0	2266788	3_prime_UTR_variant	0	NR	4e-08	7.39794000867204		0.37	[0.23-0.51] unit increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-02-21	22291604	Okada Y	2012-01-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22291604	A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.	Systemic lupus erythematosus	891 Japanese ancestry cases, 3,384 Japanese ancestry controls	1,387 Japanese ancestry cases, 28,564 Japanese ancestry controls	4q21.3	4	87037243	AFF1	AFF1			ENSG00000172493	NA	NA	rs340630-A	rs340630	0	340630	intron_variant	0	0.52	8e-09	8.09691001300806		1.21	[1.14-1.30]	Illumina [430797]	N
2012-02-21	22291604	Okada Y	2012-01-26	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/22291604	A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.	Systemic lupus erythematosus	891 Japanese ancestry cases, 3,384 Japanese ancestry controls	1,387 Japanese ancestry cases, 28,564 Japanese ancestry controls	4q25	4	108125804	LEF1	LEF1			ENSG00000138795	NA	NA	rs956237-A	rs956237	0	956237	intron_variant	0	0.33	2e-06	5.69897000433602		1.18	[1.10-1.26]	Illumina [430797]	N
2008-06-16	17634447	Stefansson H	2007-07-19	N Engl J Med	www.ncbi.nlm.nih.gov/pubmed/17634447	A genetic risk factor for periodic limb movements in sleep.	Restless legs syndrome	306 European ancestry cases, 15,664 European ancestry controls	311 European ancestry cases, 1,895 European ancestry controls	6p21.2	6	38473194	BTBD9	BTBD9			ENSG00000183826	NA	NA	rs3923809-A	rs3923809	0	3923809	intron_variant	0	0.66	1e-17	17		1.9	[1.50-2.20]	Illumina [306937]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	11q22.1	11	97811564	NR	RNA5SP347 - LINC02713	ENSG00000199315	ENSG00000255502		153982	66911	rs2405657-?	rs2405657	0	2405657	intergenic_variant	1	0.66	3e-06	5.52287874528034		1.19	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	9p21.2	9	27543283	IFNK, MOBKL2B, C9orf72	AL451123.1, C9orf72			ENSG00000285103, ENSG00000147894	NA	NA	rs3849942-?	rs3849942	0	3849942	non_coding_transcript_exon_variant	0	0.23	1e-08	8		1.23	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	12p12.3	12	17220805	NR	AC092110.1 - PSMC1P8	ENSG00000285724	ENSG00000256896		53015	162547	rs9971637-?	rs9971637	0	9971637	intergenic_variant	1	0.05	2e-06	5.69897000433602		1.48	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	9p21.2	9	27561051	NR	C9orf72			ENSG00000147894	NA	NA	rs774359-?	rs774359	0	774359	3_prime_UTR_variant	0	0.25	3e-06	5.52287874528034		1.19	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	Xp22.32	X	4678097	NR	AC074035.1 - MTND6P12	ENSG00000236513	ENSG00000235039		44525	490821	rs5916687-?	rs5916687	0	5916687	intergenic_variant	1	0.27	3e-06	5.52287874528034		1.22	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	Xq13.3	X	76127599	NR	AC233982.1 - PBDC1	ENSG00000232332	ENSG00000102390		97269	45441	rs5937496-?	rs5937496	0	5937496	regulatory_region_variant	1	0.13	6e-07	6.22184874961636		1.38	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	9p21.2	9	27536399	IFNK, MOBKL2B, C9orf72	C9orf72, AL451123.1			ENSG00000147894, ENSG00000285103	NA	NA	rs2814707-?	rs2814707	0	2814707	non_coding_transcript_exon_variant	0	0.23	7e-09	8.15490195998574		1.22	[NR]	Illumina [292768]	N
2009-09-29	19734901	van Es MA	2009-09-06	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19734901	Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.	Amyotrophic lateral sclerosis	2,323 European ancestry cases, 9,013 European ancestry controls	2,532 European ancestry cases, 5,940 European ancestry controls	19p13.11	19	17641880	UNC13A	UNC13A			ENSG00000130477	NA	NA	rs12608932-?	rs12608932	0	12608932	intron_variant	0	0.34	3e-14	13.5228787452803		1.25	[NR]	Illumina [292768]	N
2008-06-16	17558408	van Heel DA	2007-06-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17558408	A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.	Celiac disease	778 European ancestry cases, 1,422 European ancestry controls	991 European ancestry cases, 1,489 European ancestry controls	6p21.32	6	32638107	HLA-DQA1	HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1, HLA-DQA1			ENSG00000232062, ENSG00000206305, ENSG00000236418, ENSG00000228284, ENSG00000225890, ENSG00000196735	NA	NA	rs2187668-A	rs2187668	0	2187668	intron_variant	0	0.14	1e-19	19		7.04	[6.08-8.15]	Illumina [310605]	N
2008-06-16	17558408	van Heel DA	2007-06-10	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17558408	A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.	Celiac disease	778 European ancestry cases, 1,422 European ancestry controls	991 European ancestry cases, 1,489 European ancestry controls	4q27	4	122588266	IL2, TENR, KIAA1109, IL21	IL2 - IL21	ENSG00000109471	ENSG00000138684		131541	21842	rs6822844-G	rs6822844	0	6822844	regulatory_region_variant	1	0.82	1e-14	14		1.59	[1.41-1.75]	Illumina [310605]	N
2015-05-15	21353194	Cichon S	2011-02-23	Am J Hum Genet	www.ncbi.nlm.nih.gov/pubmed/21353194	Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder.	Bipolar disorder	682 European ancestry cases, 1,300 European ancestry controls	7,759 European ancestry cases, 34,062 European ancestry controls	19p13.11	19	19250926	NCAN	NCAN			ENSG00000130287	NA	NA	rs1064395-A	rs1064395	0	1064395	3_prime_UTR_variant	0	0.16	2e-09	8.69897000433602		1.17	[NR]	Illumina [511978]	N
2008-06-16	17618284	Tomlinson I	2007-07-08	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17618284	A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.	Colorectal cancer	930 European ancestry cases, 960 European ancestry controls	7,334 European ancestry cases, 5,246 European ancestry controls	8q24.21	8	127401060	intergenic	PCAT1, CCAT2, POU5F1B, CASC8			ENSG00000253438, ENSG00000280997, ENSG00000212993, ENSG00000246228	NA	NA	rs6983267-G	rs6983267	0	6983267	non_coding_transcript_exon_variant	0	0.49	1e-14	14		1.27	[1.16-1.39]	Illumina [547647]	N
2011-03-02	21244703	Wang JH	2011-01-18	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21244703	Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.	Multiple sclerosis	2,124 cases, 6,720 controls	1,618 cases, 1,988 controls	5p13.2	5	35803475	IL7R	AC137810.1, SPEF2			ENSG00000248969, ENSG00000152582	NA	NA	rs931555-?	rs931555	0	931555	intron_variant	0	NR	4e-07	6.39794000867204		1.25	[1.15-1.36]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2011-03-02	21244703	Wang JH	2011-01-18	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21244703	Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.	Multiple sclerosis	2,124 cases, 6,720 controls	1,618 cases, 1,988 controls	11q12.2	11	61026179	CD6	CD6 - AP003721.2	ENSG00000013725	ENSG00000256733		5802	29213	rs4939490-?	rs4939490	0	4939490	intergenic_variant	1	NR	1e-09	9		1.3	[1.19-1.42]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2011-03-02	21244703	Wang JH	2011-01-18	Genome Med	www.ncbi.nlm.nih.gov/pubmed/21244703	Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.	Multiple sclerosis	2,124 cases, 6,720 controls	1,618 cases, 1,988 controls	1p13.1	1	116495665	CD58	AL390066.2, AL390066.1			ENSG00000286276, ENSG00000224950	NA	NA	rs12025416-?	rs12025416	0	12025416	intron_variant	0	NR	1e-07	7		1.45	[1.25-1.69]	Affymetrix, Illumina [~ 2560000] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3q13.2 x 2q31.1	3 x 2	112779033 x 172446825	CD200R1L x ITAGA6	LINC02042 - CD200R1L-AS1 x ITGA6				NA	NA	rs1002979-? x rs12621278-?	rs1002979 x rs12621278	0	NA	regulatory_region_variant x intron_variant	NA	NR	3e-06	5.52287874528034		1.5873	[1.32-1.92]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	10p14 x 19q13.2	10 x 19	12009817 x 38244973	UPF2 x NR	UPF2 x SPINT2				NA	NA	rs10795917-? x rs8102476-?	rs10795917 x rs8102476	0	NA	intron_variant x intron_variant	NA	NR	7e-07	6.15490195998574		1.24	[1.14-1.36]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	15q21.1 x 11q13.3	15 x 11	48747600 x 69167951	CEP152 x MYEOV	CEP152 x AP003071.2				NA	NA	rs784411-? x rs12418451-?	rs784411 x rs12418451	0	NA	intron_variant x intron_variant	NA	NR	1e-07	7		1.42	[1.25-1.61]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3p14.3 x 11q13.3	3 x 11	57409039 x 69167951	DNAH12 x MYEOV	DNAH12 x AP003071.2				NA	NA	rs1916284-? x rs12418451-?	rs1916284 x rs12418451	0	NA	intron_variant x intron_variant	NA	NR	1e-06	6		1.2658	[1.15-1.41]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	7q21.3 x 10q26.13	7 x 10	98391899 x 125008303	BAIAP2L1 x CTBP2	BAIAP2L1 x CTBP2				NA	NA	rs9649213-? x rs4962416-?	rs9649213 x rs4962416	0	NA	intron_variant x intron_variant	NA	NR	1e-06	6		1.28	[1.16-1.42]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	10q25.3 x 8q24.21	10 x 8	114567791 x 127472793	ABLIM1 x NR	ABLIM1 x CASC8				NA	NA	rs10885582-? x rs1447295-?	rs10885582 x rs1447295	0	NA	intron_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.3699	[1.20-1.59]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	12q21.31 x 8q24.21	12 x 8	82770777 x 127112671	TMTC2 x NR	TMTC2 x CASC19, PCAT1				NA	NA	rs12317459-? x rs16901979-?	rs12317459 x rs16901979	0	NA	intron_variant x intron_variant	NA	NR	4e-06	5.39794000867204		2.06	[1.52-2.80]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	5q11.2 x 10q26.13	5 x 10	57834991 x 125008303	ACTBL2 x CTBP2	AC106822.1 - LINC02225 x CTBP2				NA	NA	rs10940579-? x rs4962416-?	rs10940579 x rs4962416	0	NA	regulatory_region_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.32	[1.18-1.49]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	7q31.1 x 17q24.3	7 x 17	109363517 x 71112612	C7orf66 x NR	AC002386.1 - AC073071.1 x CASC17				NA	NA	rs10277209-? x rs1859962-?	rs10277209 x rs1859962	0	NA	intergenic_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.36	[1.19-1.55]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	9q33.1 x 3q21.3	9 x 3	115068533 x 128319530	TNC x EEFSEC	DEC1, TNC x EEFSEC				NA	NA	rs7847271-? x rs10934853-?	rs7847271 x rs10934853	0	NA	intron_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.4925	[1.27-1.79]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	2q31.3 x 17q24.3	2 x 17	180176559 x 71112612	CWC22 x NR	CWC22 - AC012669.1 x CASC17				NA	NA	rs16867225-? x rs1859962-?	rs16867225 x rs1859962	0	NA	intergenic_variant x intron_variant	NA	NR	3e-06	5.52287874528034		1.5625	[1.3-1.89]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	13q14.11 x 2p21	13 x 2	44063269 x 43326810	NCRNA00284 x THADA	NRAD1 - LINC00390 x THADA				NA	NA	rs9567349-? x rs1465618-?	rs9567349 x rs1465618	0	NA	intergenic_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.6393	[1.33-2.04]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	15q14 x 8q24.21	15 x 8	34776108 x 127401060	ACTC1 x NR	AC087457.1 x CCAT2, POU5F1B, CASC8, PCAT1				NA	NA	rs543686-? x rs6983267-?	rs543686 x rs6983267	0	NA	intron_variant x non_coding_transcript_exon_variant	NA	NR	4e-06	5.39794000867204		1.24	[1.13-1.35]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	22q12.1 x 8q24.21	22 x 8	27456222 x 127310936	MN1 x NR	AL050402.2 - AL050402.1 x CASC8, PCAT1				NA	NA	rs6005451-? x rs445114-?	rs6005451 x rs445114	0	NA	regulatory_region_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.42	[1.22-1.65]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	5p15.2 x 19q13.2	5 x 19	13505322 x 41479716	DNAH5 x PPP1R14A	RPS23P5 - NENFP3 x PCAT19				NA	NA	rs4463179-? x rs887391-?	rs4463179 x rs887391	0	NA	intergenic_variant x intron_variant	NA	NR	2e-06	5.69897000433602		1.5625	[1.3-1.89]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	18q12.1 x Xp11.22	18 x X	33347811 x 51498820	C18orf34 x NUDT10	CCDC178 x LINC01496				NA	NA	rs6507016-? x rs5945619-?	rs6507016 x rs5945619	0	NA	intron_variant x non_coding_transcript_exon_variant	NA	NR	4e-06	5.39794000867204		1.2821	[1.15-1.41]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3p26.3 x 7q21.3	3 x 7	108303 x 98187015	CHL1 x LMTK2	AC066595.1 - CHL1-AS2 x LMTK2				NA	NA	rs12485321-? x rs6465657-?	rs12485321 x rs6465657	0	NA	intergenic_variant x intron_variant	NA	NR	3e-06	5.52287874528034		1.2346	[1.14-1.35]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	2q13 x 11p15.5	2 x 11	111039954 x 2212344	ACOXL x IGF2, IGF2AS, INS, TH	MIR4435-2HG, ACOXL x MIR4686 - ASCL2				NA	NA	rs3789080-? x rs7127900-?	rs3789080 x rs7127900	0	NA	intron_variant x intergenic_variant	NA	NR	4e-06	5.39794000867204		1.4085	[1.22-1.64]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	11p15.2 x 4q24	11 x 4	15333700 x 105140377	INSC x TET2	INSC - AC104361.1 x AC004069.1				NA	NA	rs11605083-? x rs7679673-?	rs11605083 x rs7679673	0	NA	intergenic_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.28	[1.15-1.43]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	8q24.13 x 11p15.5	8 x 11	123702482 x 2212344	ANXA13 x IGF2, IGF2AS, INS, TH	ANXA13 x MIR4686 - ASCL2				NA	NA	rs13258681-? x rs7127900-?	rs13258681 x rs7127900	0	NA	intron_variant x intergenic_variant	NA	NR	4e-06	5.39794000867204		1.32	[1.17-1.48]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	16q12.1 x 7q21.3	16 x 7	49360365 x 98187015	C16orf78 x LMTK2	AC007614.1 - C16orf78 x LMTK2				NA	NA	rs8057939-? x rs6465657-?	rs8057939 x rs6465657	0	NA	intergenic_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.37	[1.20-1.57]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3p12.1 x 4q22.3	3 x 4	86845328 x 94641726	VGLL3 x PDLIM5	AC108706.1 - VGLL3 x PDLIM5				NA	NA	rs9757252-? x rs17021918-?	rs9757252 x rs17021918	0	NA	intergenic_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.25	[1.13-1.37]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	6p22.3 x 8q24.21	6 x 8	17813594 x 126999692	KIF13A x NR	KIF13A x PCAT1				NA	NA	rs10456809-? x rs10086908-?	rs10456809 x rs10086908	0	NA	intron_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.25	[1.14-1.38]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	4q25 x 8q24.21	4 x 8	113079800 x 126999692	ANK2 x NR	ANK2 x PCAT1				NA	NA	rs7694725-? x rs10086908-?	rs7694725 x rs10086908	0	NA	intron_variant x intron_variant	NA	NR	2e-06	5.69897000433602		1.36	[1.20-1.55]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	6q12 x 6q25.3	6 x 6	68584593 x 160412632	BAI3 x NR	AL606923.2 - AL606923.1 x SLC22A3				NA	NA	rs9351730-? x rs9364554-?	rs9351730 x rs9364554	0	NA	intergenic_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.25	[1.13-1.37]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3p25.2 x 10q11.22	3 x 10	12510308 x 46046326	TSEN2 x MSMB	TSEN2 x MSMB				NA	NA	rs6766510-? x rs10993994-?	rs6766510 x rs10993994	0	NA	intron_variant x 5_prime_UTR_variant	NA	NR	2e-06	5.69897000433602		1.58	[1.31-1.91]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	4p16.2 x 19q13.2	4 x 19	5757142 x 41479716	EVC x PPP1R14A	EVC, CRMP1 x PCAT19				NA	NA	rs735172-? x rs887391-?	rs735172 x rs887391	0	NA	intron_variant x intron_variant	NA	NR	2e-06	5.69897000433602		1.31	[1.17-1.46]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	12q13.11 x 22q13.2	12 x 22	46978487 x 43104206	AMIGO2 x TTLL1, BIK, MCAT, PACSIN2	AC079906.1 - AMIGO2 x AL022237.1 - BIK				NA	NA	rs2711721-? x rs5759167-?	rs2711721 x rs5759167	0	NA	intergenic_variant x TF_binding_site_variant	NA	NR	2e-06	5.69897000433602		1.28	[1.16-1.42]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	8q21.13 x 9q33.2	8 x 9	78044423 x 121665094	PKIA x DAB2IC	AC062004.1 - AC084706.1 x DAB2IP				NA	NA	rs2219968-? x rs1571801-?	rs2219968 x rs1571801	0	NA	intergenic_variant x intron_variant	NA	NR	6e-07	6.22184874961636		1.3	[1.17-1.43]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	13q31.3 x 8p21.2	13 x 8	90213292 x 23668950	MIR622 x NKX3.1	FAR1P1 - KRT18P27 x SINHCAFP3 - NKX3-1				NA	NA	rs16944141-? x rs1512268-?	rs16944141 x rs1512268	0	NA	intergenic_variant x intergenic_variant	NA	NR	3e-06	5.52287874528034		1.5385	[1.28-1.85]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	12q13.11 x 17q12	12 x 17	48417317 x 37738049	ANP32D x HNF1B	OR8S21P, AC090115.1 x HNF1B				NA	NA	rs4489787-? x rs4430796-?	rs4489787 x rs4430796	0	NA	non_coding_transcript_exon_variant x intron_variant	NA	NR	1e-06	6		1.47	[1.25-1.72]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	18q12.3 x 3q21.3	18 x 3	45145697 x 128319530	MIR4319 x EEFSEC	AC090376.1 x EEFSEC				NA	NA	rs998124-? x rs10934853-?	rs998124 x rs10934853	0	NA	intron_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.33	[1.18-1.51]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	2q33.1 x 11q13.3	2 x 11	198304372 x 69227200	PLCL1 x MYEOV	PLCL1, LINC01923 x AP003071.2 - MYEOV				NA	NA	rs13398206-? x rs10896449-?	rs13398206 x rs10896449	0	NA	intron_variant x intergenic_variant	NA	NR	4e-06	5.39794000867204		1.24	[1.13-1.36]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	14q11.2 x 11q13.3	14 x 11	20556460 x 69167951	RNASE9 x MYEOV	RNASE9 x AP003071.2				NA	NA	rs1243647-? x rs12418451-?	rs1243647 x rs12418451	0	NA	missense_variant x intron_variant	NA	NR	1e-06	6		1.3333	[1.19-1.49]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	9q22.2 x 4q24	9 x 4	90793457 x 105140377	SYK x TET2	OR7E108P - SYK x AC004069.1				NA	NA	rs290258-? x rs7679673-?	rs290258 x rs7679673	0	NA	intergenic_variant x intron_variant	NA	NR	1e-06	6		1.3333	[1.19-1.49]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	9p24.1 x 8q24.21	9 x 8	8012418 x 127472793	C9orf123 x NR	AL135923.2 - PTPRD x CASC8				NA	NA	rs12682851-? x rs1447295-?	rs12682851 x rs1447295	0	NA	intergenic_variant x intron_variant	NA	NR	2e-06	5.69897000433602		1.3889	[1.22-1.59]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	6q22.31 x 17q12	6 x 17	122961796 x 37714971	CLVS2 x HNF1B	ATP5MGP2 - AL591428.1 x HNF1B				NA	NA	rs13192613-? x rs11649743-?	rs13192613 x rs11649743	0	NA	intergenic_variant x intron_variant	NA	NR	3e-06	5.52287874528034		1.37	[1.20-1.56]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3p26.3 x 22q13.1	3 x 22	1470903 x 40056115	CNTN6 x TNRC6B	CNTN6 - RPL23AP38 x TNRC6B				NA	NA	rs6763848-? x rs9623117-?	rs6763848 x rs9623117	0	NA	intergenic_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.3	[1.16-1.45]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	20q13.33 x 19q13.33	20 x 19	63037684 x 50861367	LOC63930 x KLK3	LINC01749 x KLK3 - KLK2				NA	NA	rs6089829-? x rs2735839-?	rs6089829 x rs2735839	0	NA	intron_variant x intergenic_variant	NA	NR	3e-06	5.52287874528034		1.3514	[1.19-1.54]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	7p14.1 x 8q24.21	7 x 8	40925528 x 127472793	INHBA x NR	SUGCT - LINC01450 x CASC8				NA	NA	rs7789197-? x rs1447295-?	rs7789197 x rs1447295	0	NA	intergenic_variant x intron_variant	NA	NR	3e-06	5.52287874528034		1.5152	[1.27-1.79]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	5q13.1 x 3p12.1	5 x 3	67537429 x 87061524	CD180 x NR	AC112206.2 x PPATP1 - AC107204.1				NA	NA	rs7717572-? x rs2660753-?	rs7717572 x rs2660753	0	NA	intron_variant x intergenic_variant	NA	NR	3e-06	5.52287874528034		1.94	[1.47-2.56]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	22q11.22 x 4q24	22 x 4	22490916 x 105140377	ZNF280B x TET2	ZNF280B x AC004069.1				NA	NA	rs5751168-? x rs7679673-?	rs5751168 x rs7679673	0	NA	intron_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.44	[1.23-1.67]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	14q32.31 x 3q21.3	14 x 3	101260770 x 128319530	MIR656 x EEFSEC	AL359682.1 x EEFSEC				NA	NA	rs2400997-? x rs10934853-?	rs2400997 x rs10934853	0	NA	intron_variant x intron_variant	NA	NR	3e-06	5.52287874528034		1.25	[1.14-1.38]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	22q13.1 x 11p15.5	22 x 11	40279087 x 2212344	TNRC6B x IGF2, IGF2AS, INS, TH	TNRC6B x MIR4686 - ASCL2				NA	NA	rs4821941-? x rs7127900-?	rs4821941 x rs7127900	0	NA	intron_variant x intergenic_variant	NA	NR	4e-06	5.39794000867204		1.3	[1.16-1.46]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	22q13.1 x 11p15.5	22 x 11	40258272 x 2212344	TNRC6B x IGF2, IGF2AS, INS, TH	TNRC6B x MIR4686 - ASCL2				NA	NA	rs12628051-? x rs7127900-?	rs12628051 x rs7127900	0	NA	intron_variant x intergenic_variant	NA	NR	3e-06	5.52287874528034		1.3	[1.17-1.46]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	8q21.13 x 9q33.2	8 x 9	82161594 x 121665094	SNX16 x DAB2IC	AC060765.2 x DAB2IP				NA	NA	rs13264970-? x rs1571801-?	rs13264970 x rs1571801	0	NA	intron_variant x intron_variant	NA	NR	4e-06	5.39794000867204		1.2987	[1.16-1.45]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	1p34.3 x 17q12	1 x 17	37731169 x 37738049	EPHA10 x HNF1B	EPHA10 x HNF1B				NA	NA	rs731174-? x rs4430796-?	rs731174 x rs4430796	0	NA	intron_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.27	[1.15-1.40]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	6p22.1 x 8p21.2	6 x 8	29734733 x 23668950	LOC285830 x NKX3.1	HLA-F, HLA-F-AS1 x SINHCAFP3 - NKX3-1				NA	NA	rs2523395-? x rs1512268-?	rs2523395 x rs1512268	0	NA	intron_variant x intergenic_variant	NA	NR	2e-06	5.69897000433602		1.24	[1.14-1.35]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	3q26.31 x 7p15.1	3 x 7	173125487 x 27936944	SPATA16 x JAZF1	SPATA16 x JAZF1				NA	NA	rs11720607-? x rs10486567-?	rs11720607 x rs10486567	0	NA	intron_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.3699	[1.20-1.59]	Affymetrix, Illumina [1117531] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	15q26.2 x 8q24.21	15 x 8	96459423 x 127472793	NR2F2 x NR	AC087477.4 - RN7SKP254 x CASC8				NA	NA	rs11637980-? x rs1447295-?	rs11637980 x rs1447295	0	NA	intergenic_variant x intron_variant	NA	NR	2e-06	5.69897000433602		1.4706	[1.27-1.72]	Affymetrix, Illumina [1117531] (imputed)	N
2008-06-16	17401366	Gudmundsson J	2007-04-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17401366	Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.	Prostate cancer	1,453 European ancestry cases, 3,064 European ancestry controls	1,210 European ancestry cases, 2,445 European ancestry controls, 373 African American cases, 372 African American controls	8q24.21	8	127472793	intergenic	CASC8			ENSG00000246228	NA	NA	rs1447295-A	rs1447295	0	1447295	intron_variant	0	0.09	6e-18	17.2218487496164		1.6	[1.43-1.77]	Illumina [316515]	N
2008-06-16	17401366	Gudmundsson J	2007-04-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17401366	Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.	Prostate cancer	1,453 European ancestry cases, 3,064 European ancestry controls	1,210 European ancestry cases, 2,445 European ancestry controls, 373 African American cases, 372 African American controls	8q24.21	8	127112671	intergenic	PCAT1, CASC19			ENSG00000253438, ENSG00000254166	NA	NA	rs16901979-A	rs16901979	0	16901979	intron_variant	0	0.03	1e-12	12	(EA)	1.79	[1.53-2.11]	Illumina [316515]	N
2008-06-16	17401366	Gudmundsson J	2007-04-01	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/17401366	Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.	Prostate cancer	1,453 European ancestry cases, 3,064 European ancestry controls	1,210 European ancestry cases, 2,445 European ancestry controls, 373 African American cases, 372 African American controls	8q24.21	8;8;8;8;8;8;8;8;8;8;8;8;8;8	127081032;127115007;127072294;127063445;127069276;127068178;127125423;127081052;127081233;127075659;127110414;127071852;127080210;127104255	intergenic	CASC19; PCAT1; PRNCR1; CASC19; PCAT1; PCAT1; PCAT1; PCAT1; PCAT1; CASC19; PCAT1; CASC19; PCAT1; PRNCR1; CASC19; PCAT1; PRNCR1; CASC19; PCAT1; CASC19; PCAT1; PCAT1; CASC19; PRNCR1; PCAT1; CASC19; PCAT1				NA	NA	rs1031588-G; rs1456305-T; rs6994316-A; rs1456314-G; rs7825414-G; rs17831626-T; rs7816535-G; rs1016343-T; rs1551510-G; rs6470494-T; rs1378897-G; rs6993569-G; rs1016342-C; rs1456306-C	rs1031588; rs1456305; rs6994316; rs1456314; rs7825414; rs17831626; rs7816535; rs1016343; rs1551510; rs6470494; rs1378897; rs6993569; rs1016342; rs1456306	0	NA	non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; non_coding_transcript_exon_variant; intron_variant; intron_variant; intron_variant; non_coding_transcript_exon_variant; intron_variant	NA	0.022	3e-15	14.5228787452803	(EA)	2.1	[1.75-2.53]	Illumina [316515]	N
2012-02-02	22233651	Kwak SH	2012-01-10	Diabetes	www.ncbi.nlm.nih.gov/pubmed/22233651	A genome-wide association study of gestational diabetes mellitus in Korean women.	Diabetes (gestational)	468 Korean ancestry cases, 1,242 Korean ancestry controls	931 Korean ancestry cases, 783 Korean ancestry controls	11q14.3	11	92965261	MTNR1B	SNRPGP16 - AP003171.1	ENSG00000255287	ENSG00000254874		27595	536	rs10830962-G	rs10830962	0	10830962	intergenic_variant	1	0.430	2e-13	12.698970004336		1.454	[1.315-1.608]	Affymetrix [2188613] (imputed)	N
2012-02-02	22233651	Kwak SH	2012-01-10	Diabetes	www.ncbi.nlm.nih.gov/pubmed/22233651	A genome-wide association study of gestational diabetes mellitus in Korean women.	Diabetes (gestational)	468 Korean ancestry cases, 1,242 Korean ancestry controls	931 Korean ancestry cases, 783 Korean ancestry controls	3q27.2	3	185811292	IGF2BP2	IGF2BP2			ENSG00000073792	NA	NA	rs1470579-C	rs1470579	0	1470579	intron_variant	0	0.293	2e-07	6.69897000433602		1.332	[1.197-1.484]	Affymetrix [2188613] (imputed)	N
2012-02-02	22233651	Kwak SH	2012-01-10	Diabetes	www.ncbi.nlm.nih.gov/pubmed/22233651	A genome-wide association study of gestational diabetes mellitus in Korean women.	Diabetes (gestational)	468 Korean ancestry cases, 1,242 Korean ancestry controls	931 Korean ancestry cases, 783 Korean ancestry controls	6p22.3	6	20661019	CDKAL1	CDKAL1			ENSG00000145996	NA	NA	rs7754840-C	rs7754840	0	7754840	intron_variant	0	0.445	7e-16	15.1549019599857		1.518	[1.372-1.680]	Affymetrix [2188613] (imputed)	N
2012-03-31	22219177	Tao S	2012-01-04	Carcinogenesis	www.ncbi.nlm.nih.gov/pubmed/22219177	A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants.	Prostate cancer (SNP x SNP interaction)	4,723 European ancestry cases, 4,792 European ancestry controls	NA	1p35.3 x 19q13.2	1 x 19	29712815 x 38244973	PTPRU x NR	AC092265.1 - AL645944.2 x SPINT2				NA	NA	rs1866967-? x rs8102476-?	rs1866967 x rs8102476	0	NA	intergenic_variant x intron_variant	NA	NR	5e-06	5.30102999566398		1.2195	[1.12-1.33]	Affymetrix, Illumina [1117531] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	7p12.2	7	50360730	IKZF1	IKZF1			ENSG00000185811	NA	NA	rs12718597-A	rs12718597	0	12718597	intron_variant	0	NR	5e-13	12.301029995664		0	[0.002-0.004] fl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	10q11.22	10	45529281	MARCH8	MARCH8			ENSG00000165406	NA	NA	rs11239550-G	rs11239550	0	11239550	intron_variant	0	NR	1e-10	10		0	[0.002-0.003] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	19p13.13	19	12821455	RTBDN	HOOK2			ENSG00000095066	NA	NA	rs7255045-A	rs7255045	0	7255045	intron_variant	0	NR	2e-12	11.698970004336		0	[0.002-0.004] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	6q23.3	6	135105435	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		2379	75873	rs4895441-G	rs4895441	0	4895441	regulatory_region_variant	1	NR	7e-86	85.1549019599858		0.01	[0.007-0.009] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	7q22.1	7	100616392	TFR2	MOSPD3 - TFR2	ENSG00000106330	ENSG00000106327		1008	4024	rs7786877-G	rs7786877	0	7786877	intergenic_variant	1	NR	3e-11	10.5228787452803		0	[0.002-0.004] fl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	22q13.33	22	50533323	ECGF1	ODF3B - U62317.4	ENSG00000177989	ENSG00000273272		743	7785	rs131794-A	rs131794	0	131794	regulatory_region_variant	1	NR	1e-15	15		0	[0.003-0.005] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	2p16.1	2	60381624	BCL11A	AC007381.1			ENSG00000228590	NA	NA	rs2540917-C	rs2540917	0	2540917	intron_variant	0	NR	1e-14	14		0	[0.002-0.004] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	16p13.3	16	254804	ITFG3	FAM234A			ENSG00000167930	NA	NA	rs7189020-T	rs7189020	0	7189020	intron_variant	0	NR	2e-12	11.698970004336		0	[0.002-0.004] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	9p24.1	9	4856877	RCL1	RCL1			ENSG00000120158	NA	NA	rs10758658-A	rs10758658	0	10758658	intron_variant	0	NR	3e-20	19.5228787452803		0	[0.003-0.005] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	22q12.3	22	37066896	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs855791-A	rs855791	0	855791	missense_variant	0	NR	3e-25	24.5228787452803		0.09	[0.07-0.11] g/dl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	NR	6e-19	18.2218487496164		0.16	[0.13-0.20] g/dl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	2p21	2	46126027	PRKCE	PRKCE			ENSG00000171132	NA	NA	rs10495928-G	rs10495928	0	10495928	intron_variant	0	NR	7e-13	12.1549019599857		0.06	[0.05-0.08] g/dl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	7q36.1	7	151717955	PRKAG2	PRKAG2			ENSG00000106617	NA	NA	rs10224002-G	rs10224002	0	10224002	intron_variant	0	NR	3e-15	14.5228787452803		0.07	[0.05-0.09] g/dl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	10q22.1	10	69333636	HK1	HK1			ENSG00000156515	NA	NA	rs16926246-T	rs16926246	0	16926246	intron_variant	0	NR	2e-11	10.698970004336		0.11	[0.08-0.14] g/dl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	20q13.2	20	52701812	TSHZ2	AL031674.1 - AL161945.1	ENSG00000232294	ENSG00000286250		2340	139124	rs6013509-A	rs6013509	0	6013509	intergenic_variant	1	NR	1e-10	10		0.06	[0.05-0.08] g/dl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	12q24.12	12	111634620	TRAFD1	ATXN2-AS - BRAP	ENSG00000258099	ENSG00000089234		34364	7526	rs11065987-A	rs11065987	0	11065987	intergenic_variant	1	NR	1e-11	11		0.06	[0.04-0.08] g/dl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Other erythrocyte phenotypes	24,167 European ancestry individuals	9,456 European ancestry individuals	6q23.3	6	135114363	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		11307	66945	rs9483788-G	rs9483788	0	9483788	intergenic_variant	1	NR	1e-47	47	(RBC)	0	[0.012-0.016] 1 M cells/mm^3 increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Other erythrocyte phenotypes	24,167 European ancestry individuals	9,456 European ancestry individuals	6q23.3	6	135102071	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs9373124-C	rs9373124	0	9373124	intron_variant	0	NR	7e-14	13.1549019599857	(MCHC)	0	[0.002-0.003] g/dl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Other erythrocyte phenotypes	24,167 European ancestry individuals	9,456 European ancestry individuals	7q22.1	7	100747483	EPO	ZAN			ENSG00000146839	NA	NA	rs2075671-A	rs2075671	0	2075671	intron_variant	0	NR	1e-09	9	(RBC)	0	[0.005-0.009] 1 M cell/mm^3 increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Other erythrocyte phenotypes	24,167 European ancestry individuals	9,456 European ancestry individuals	1q23.1	1	158642758	SPTA1	SPTA1			ENSG00000163554	NA	NA	rs857721-A	rs857721	0	857721	intron_variant	0	NR	1e-10	10	(MCHC)	0	[0.001-0.002] g/dl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	5q33.2	5	153599994	AMPA1, GRIA1	GRIA1			ENSG00000155511	NA	NA	rs12658202-?	rs12658202	0	12658202	intron_variant	0	0.45	9e-06	5.04575749056067	(height)	0.11	[0.06-0.16] mm increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	16p11.2	16	29874126	SEZ6L2	SEZ6L2			ENSG00000174938	NA	NA	rs4787483-?	rs4787483	0	4787483	intron_variant	0	0.34	2e-06	5.69897000433602	(waist cirumference)	0.16	[0.09-0.23] mm increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	7q22.1	7	99610253	ZNF498	TMEM225B			ENSG00000244219	NA	NA	rs7792939-?	rs7792939	0	7792939	intron_variant	0	0.15	5e-06	5.30102999566398	(brachial circumference)	0.26	[0.15-0.37] mm increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	7q22.1	7	99610253	ZNF498	TMEM225B			ENSG00000244219	NA	NA	rs7792939-?	rs7792939	0	7792939	intron_variant	0	0.15	4e-06	5.39794000867204	(weight)	0.26	[0.15-0.37] kg increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	5q33.3	5	156712558	SGCD	SGCD, AC025434.1			ENSG00000170624, ENSG00000254163	NA	NA	rs157350-?	rs157350	0	157350	intron_variant	0	0.11	6e-06	5.22184874961636	(hip circumference)	0.31	[0.18-0.44] mm decrease	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	5q33.3	5	156712558	SGCD	SGCD, AC025434.1			ENSG00000170624, ENSG00000254163	NA	NA	rs157350-?	rs157350	0	157350	intron_variant	0	0.11	4e-06	5.39794000867204	(brachial circumference)	0.31	[0.18-0.44] mm decrease	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	1p36.32	1	5110652	intergenic	LINC02782 - AL139823.1	ENSG00000231510	ENSG00000284616		19753	191276	rs7513590-?	rs7513590	0	7513590	regulatory_region_variant	1	0.10	5e-06	5.30102999566398	(height)	0.31	[0.17-0.45] mm decrease	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	2p22.3	2	36299293	CRIM1	MRPL50P1 - AC009414.1	ENSG00000234587	ENSG00000233752		574151	95	rs1863080-?	rs1863080	0	1863080	intergenic_variant	1	0.10	8e-06	5.09691001300806	(brachial circumference)	0.31	[0.17-0.45] mm increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	14q32.12	14	94096847	LOC122509, FAM14B	IFI27L1, IFI27L1			ENSG00000165948, ENSG00000276880	NA	NA	rs7157940-?	rs7157940	0	7157940	5_prime_UTR_variant	0	0.46	3e-06	5.52287874528034	(weight)	0.12	[0.07-0.17] kg increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	14q23.3	14	65178532	MAX	RNU2-14P - LINC02324	ENSG00000222985	ENSG00000255002		53990	18722	rs7158173-?	rs7158173	0	7158173	regulatory_region_variant	1	0.48	4e-06	5.39794000867204	(waist circumference)	0.11	[0.06-0.16] mm decrease	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	2q31.1	2	173497621	intergenic	PPIAP66 - AC013410.1	ENSG00000226131	ENSG00000237016		11259	77489	rs7590983-?	rs7590983	0	7590983	intergenic_variant	1	0.05	6e-06	5.22184874961636	(BMI)	0.46	[0.26-0.66] kg/m2 increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	7q22.1	7	99610253	ZNF498	TMEM225B			ENSG00000244219	NA	NA	rs7792939-?	rs7792939	0	7792939	intron_variant	0	0.15	6e-06	5.22184874961636	(hip circumference)	0.26	[0.15-0.37] mm increase	Illumina [316730]	N
2009-03-30	19260139	Polasek O	2009-02-01	Croat Med J	www.ncbi.nlm.nih.gov/pubmed/19260139	Genome-wide association study of anthropometric traits in Korcula Island, Croatia.	Anthropometric traits	898 Korculan (founder/genetic isolate) individuals	NA	13q14.3	13	50411982	XTP6	DLEU1			ENSG00000176124	NA	NA	rs201789-?	rs201789	0	201789	intron_variant	0	0.28	6e-06	5.22184874961636	(brachial circumference)	0.17	[0.10-0.24] mm increase	Illumina [316730]	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	7q22.1	7	99521178	ZKSCAN5	ZKSCAN5			ENSG00000196652	NA	NA	rs11761528-T	rs11761528	0	11761528	intron_variant	0	0.08	3e-36	35.5228787452803		0.16	[0.14-0.18] umol/L decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	15q15.1	15	40068540	BMF	SRP14-AS1			ENSG00000248508	NA	NA	rs7181230-G	rs7181230	0	7181230	intron_variant	0	0.33	5e-11	10.301029995664		0.05	[0.03-0.07 u mol/L increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	10q23.33	10	94991513	CYP2C9	CYP2C9 - CYP2C59P	ENSG00000138109	ENSG00000228460		1422	15613	rs2185570-C	rs2185570	0	2185570	intergenic_variant	1	0.13	2e-08	7.69897000433602		0.06	[0.04-0.08] u mol/L decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	7q22.1	7	99891948	TRIM4, CYP3A43	TRIM4			ENSG00000146833	NA	NA	rs17277546-A	rs17277546	0	17277546	3_prime_UTR_variant	0	0.05	2e-11	10.698970004336		0.11	[0.07-0.15] umol/L decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	19q13.33	19	47898636	SULT2A1	SULT2A1 - BSPH1	ENSG00000105398	ENSG00000188334		12321	69410	rs2637125-A	rs2637125	0	2637125	intergenic_variant	1	0.15	3e-19	18.5228787452803		0.09	[0.07-0.11] umol/L decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	10q23.33	10	92725454	HHEX	Y_RNA - EXOC6	ENSG00000265852	ENSG00000138190		14846	101377	rs2497306-C	rs2497306	0	2497306	intergenic_variant	1	0.49	5e-09	8.30102999566398		0.04	[0.02-0.06] umol/L decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	2q13	2	111191750	BCL2L11	MIR4435-2HG			ENSG00000172965	NA	NA	rs6738028-G	rs6738028	0	6738028	intron_variant	0	0.40	2e-08	7.69897000433602		0.04	[0.02-0.06] umol/L decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2011-05-26	21533175	Zhai G	2011-04-14	PLoS Genet	www.ncbi.nlm.nih.gov/pubmed/21533175	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	Dehydroepiandrosterone sulphate levels	14,846 European ancestry individuals	NA	7q22.1	7	99360257	ARPC1A	ARPC1A, AC004922.1			ENSG00000241685, ENSG00000284292	NA	NA	rs740160-T	rs740160	0	740160	intron_variant	0	0.05	2e-16	15.698970004336		0.15	[0.11-0.19] umol/L increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	10q26.13	10	122459759	ARMS2, HTRA1	HTRA1, BX842242.1			ENSG00000166033, ENSG00000285955	NA	NA	rs3793917-?	rs3793917	0	3793917	non_coding_transcript_exon_variant	0	0.2	4e-24	23.397940008672	(EA)	1.45	[1.35-1.56]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	19p13.3	19	3944242	DAPK3, ITGB1BP3	NMRK2 - DAPK3	ENSG00000077009	ENSG00000167657		1826	14211	rs10406174-A	rs10406174	0	10406174	regulatory_region_variant	1	0.11	6e-06	5.22184874961636	(EA)	1.24	[1.13-1.36]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	1q31.3	1	196685194	CFH	CFH			ENSG00000000971	NA	NA	rs1061147-A	rs1061147	0	1061147	synonymous_variant	0	0.37	7e-32	31.1549019599857		1.4	[1.32-1.48]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	4q13.1	4	62476552	intergenic	AC105313.1 - AC074087.1	ENSG00000250249	ENSG00000248847		184215	12943	rs6819266-?	rs6819266	0	6819266	intergenic_variant	1	0.62	8e-06	5.09691001300806		1.15	[1.09-1.22]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	8q24.21	8	126320412	intergenic	LINC00861 - AC087667.1	ENSG00000245164	ENSG00000244791		27624	5042	rs11986011-T	rs11986011	0	11986011	intergenic_variant	1	0.02	5e-06	5.30102999566398		2.5	[1.68-3.71]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	11q14.3	11	89157946	TYR	GRM5 - TYR	ENSG00000168959	ENSG00000077498		92001	19929	rs10830228-A	rs10830228	0	10830228	intergenic_variant	1	0.42	9e-06	5.04575749056067		1.12	[1.06-1.18]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	19p13.3	19	3944242	DAPK3, ITGB1BP3	NMRK2 - DAPK3	ENSG00000077009	ENSG00000167657		1826	14211	rs10406174-A	rs10406174	0	10406174	regulatory_region_variant	1	0.11	7e-06	5.15490195998574		1.24	[1.12-1.36]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	19q13.32	19	44892362	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-A	rs2075650	0	2075650	intron_variant	0	0.86	3e-06	5.52287874528034		1.21	[1.11 - 1.32]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	1q31.3	1	196677046	CFH	CFH			ENSG00000000971	NA	NA	rs1329424-T	rs1329424	0	1329424	non_coding_transcript_exon_variant	0	0.38	2e-31	30.698970004336	(EA)	1.41	[1.33-1.49]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	1q25.2	1	177599664	intergenic	AL136114.1			ENSG00000227579	NA	NA	rs16851585-?	rs16851585	0	16851585	intron_variant	0	0.08	5e-06	5.30102999566398	(EA)	1.3	[1.16-1.45]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	1q32.2	1	207866126	CD34, CD46	MIR29B2CHG			ENSG00000203709	NA	NA	rs1967689-?	rs1967689	0	1967689	intron_variant	0	0.75	5e-06	5.30102999566398	(EA)	1.18	[1.1-1.25]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	2q14.2	2	120544335	INHBB, GLI2	AC073257.2			ENSG00000237614	NA	NA	rs6721654-T	rs6721654	0	6721654	non_coding_transcript_exon_variant	0	0.08	7e-06	5.15490195998574	(EA)	1.26	[1.14-1.40]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	4q26	4	116003028	intergenic	AC027613.1			ENSG00000249259	NA	NA	rs17586843-T	rs17586843	0	17586843	intron_variant	0	0.78	2e-06	5.69897000433602	(EA)	1.18	[1.10-1.27]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	6q21	6	105812253	intergenic	AL591518.1			ENSG00000284999	NA	NA	rs7750345-A	rs7750345	0	7750345	intron_variant	0	0.75	7e-06	5.15490195998574	(EA)	1.16	[1.09-1.24]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	7p14.1	7	42136683	GLI3	GLI3			ENSG00000106571	NA	NA	rs2049622-?	rs2049622	0	2049622	intron_variant	0	0.51	9e-06	5.04575749056067	(EA)	1.15	[1.08-1.2]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	8q24.21	8	126320412	FAM84B	LINC00861 - AC087667.1	ENSG00000245164	ENSG00000244791		27624	5042	rs11986011-T	rs11986011	0	11986011	intergenic_variant	1	0.02	5e-06	5.30102999566398	(EA)	2.5	[1.68-3.71]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	10q21.1	10	52815236	MBL2	MBL2 - Y_RNA	ENSG00000165471	ENSG00000265852		43536	37371	rs6480975-C	rs6480975	0	6480975	intergenic_variant	1	0.84	3e-06	5.52287874528034	(EA)	1.21	[1.12-1.32]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	11q14.1	11	83110340	PCF11, RAB30	RAB30-DT - C1DP5	ENSG00000246067	ENSG00000254965		2551	720	rs4293143-?	rs4293143	0	4293143	intergenic_variant	1	0.31	8e-06	5.09691001300806	(EA)	1.18	[1.1-1.27]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	11q14.3	11	89180495	TYR	TYR			ENSG00000077498	NA	NA	rs621313-?	rs621313	0	621313	intron_variant	0	0.49	4e-06	5.39794000867204	(EA)	1.15	[1.09-1.2]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	13q13.3	13	37491309	POSTN, TRPC4	LINC01048 - LINC00547	ENSG00000230390	ENSG00000275226		6540	43631	rs9646096-?	rs9646096	0	9646096	intergenic_variant	1	0.05	6e-06	5.22184874961636	(EA)	1.35	[1.19-1.54]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	19q13.32	19	44888997	PVRL2	NECTIN2, AC011481.2			ENSG00000130202, ENSG00000267282	NA	NA	rs6857-?	rs6857	0	6857	3_prime_UTR_variant	0	0.85	1e-06	6	(EA)	1.23	[1.14-1.35]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	19q13.32	19	44892362	APOE, TOMM40	TOMM40			ENSG00000130204	NA	NA	rs2075650-A	rs2075650	0	2075650	intron_variant	0	0.86	1e-06	6	(EA)	1.23	[1.13-1.34]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	1q32.2	1	207866126	CD34, CD46	MIR29B2CHG			ENSG00000203709	NA	NA	rs1967689-?	rs1967689	0	1967689	intron_variant	0	0.75	5e-06	5.30102999566398		1.18	[1.1-1.25]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	2q14.2	2	120525054	INHBB, GLI2	LINC01101 - AC073257.2	ENSG00000280409	ENSG00000237614		58836	17851	rs17050244-?	rs17050244	0	17050244	regulatory_region_variant	1	0.11	5e-07	6.30102999566398		1.28	[1.16-1.41]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	4q26	4	116012923	intergenic	AC027613.1			ENSG00000249259	NA	NA	rs7676999-?	rs7676999	0	7676999	intron_variant	0	0.79	1e-06	6		1.19	[1.11-1.28]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	12q15	12	68385633	MDM1	LINC02384			ENSG00000251301	NA	NA	rs416350-?	rs416350	0	416350	intron_variant	0	NR	4e-08	7.39794000867204	(Hyperthymic)	2.1	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	13q31.1	13	84458192	SLITRK1	AL162493.1 - MTND4P1	ENSG00000288016	ENSG00000228597		9589	61911	rs17371334-?	rs17371334	0	17371334	intergenic_variant	1	NR	2e-06	5.69897000433602	(Cyclothymic)	1.05	[NR] unit decrease	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	2p24.2	2	18062268	intergenic	KCNS3			ENSG00000170745	NA	NA	rs4075511-?	rs4075511	0	4075511	intron_variant	0	NR	3e-06	5.52287874528034	(Irritable)	0.93	[NR] unit decrease	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	4p15.32	4	17133720	intergenic	AC106894.1 - LINC02493	ENSG00000249998	ENSG00000250819		59817	38037	rs4698169-?	rs4698169	0	4698169	intergenic_variant	1	NR	2e-06	5.69897000433602	(Anxious)	2.11	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	12q23.3	12	108209193	WSCD2	WSCD2			ENSG00000075035	NA	NA	rs7313402-?	rs7313402	0	7313402	intron_variant	0	NR	8e-06	5.09691001300806	(Anxious)	1.13	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	22q13.31	22	45566024	FBLN1	FBLN1			ENSG00000077942	NA	NA	rs1985671-?	rs1985671	0	1985671	intron_variant	0	NR	2e-08	7.69897000433602	(Hyperthymic)	1.06	[NR] unit decrease	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	1q32.3	1	211981666	INTS7	INTS7			ENSG00000143493	NA	NA	rs17018311-?	rs17018311	0	17018311	intron_variant	0	NR	2e-08	7.69897000433602	(Irritable)	4.21	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	3p24.3	3	20179220	SGOL1	SGO1, SGO1-AS1			ENSG00000129810, ENSG00000231304	NA	NA	rs6767049-?	rs6767049	0	6767049	intron_variant	0	NR	2e-06	5.69897000433602	(Dysthymic)	0.77	[NR] unit decrease	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	4q34.2	4	175740936	GPM6A	GPM6A			ENSG00000150625	NA	NA	rs17599018-?	rs17599018	0	17599018	intron_variant	0	NR	2e-06	5.69897000433602	(Dysthymic)	0.98	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	11p12	11	39887112	LRRC4C	AC021749.1 - AC021820.1	ENSG00000270588	ENSG00000255347		12724	196598	rs11035577-?	rs11035577	0	11035577	intergenic_variant	1	NR	6e-06	5.22184874961636	(Dysthymic)	1.03	[NR] unit decrease	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	12q14.1	12	59046451	intergenic	AC068305.2			ENSG00000257443	NA	NA	rs17121944-?	rs17121944	0	17121944	intron_variant	0	NR	4e-06	5.39794000867204	(Dysthymic)	2.66	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	18q12.1	18	29026683	CDH2	AC023932.1 - RNU6-408P	ENSG00000271238	ENSG00000251719		201857	21937	rs2155929-?	rs2155929	0	2155929	intergenic_variant	1	NR	5e-06	5.30102999566398	(Dysthymic)	1.01	[NR] unit increase	Affymetrix [703012]	N
2012-03-30	22365631	Greenwood TA	2012-02-22	Biol Psychiatry	www.ncbi.nlm.nih.gov/pubmed/22365631	Genome-wide association study of temperament in bipolar disorder reveals significant associations with three novel Loci.	Temperament (bipolar disorder)	1,263 European ancestry cases, 1,434 European ancestry controls	NA	21q22.2	21	39197853	BRWD1	BRWD1			ENSG00000185658	NA	NA	rs2150410-?	rs2150410	0	2150410	intron_variant	0	NR	4e-06	5.39794000867204	(Hyperthymic)	1.69	[NR] unit decrease	Affymetrix [703012]	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	6p21.1	6	45917324	intergenic	CLIC5			ENSG00000112782	NA	NA	rs4714888-T	rs4714888	0	4714888	intron_variant	0	0.05	8e-06	5.09691001300806		1.3	[1.16-1.47]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	6q21	6	105805124	intergenic	AL591518.1			ENSG00000284999	NA	NA	rs1355023-T	rs1355023	0	1355023	intron_variant	0	0.69	6e-06	5.22184874961636		1.13	[1.07-1.20]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	10q21.1	10	52815236	MBL2	MBL2 - Y_RNA	ENSG00000165471	ENSG00000265852		43536	37371	rs6480975-C	rs6480975	0	6480975	intergenic_variant	1	0.84	2e-06	5.69897000433602		1.21	[1.12-1.32]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	10q26.13	10	122459759	ARMS2, HTRA1	HTRA1, BX842242.1			ENSG00000166033, ENSG00000285955	NA	NA	rs3793917-?	rs3793917	0	3793917	non_coding_transcript_exon_variant	0	0.26	1e-25	25		1.39	[1.32-1.49]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	13q13.3	13	37491309	POSTN, TRPC4	LINC01048 - LINC00547	ENSG00000230390	ENSG00000275226		6540	43631	rs9646096-?	rs9646096	0	9646096	intergenic_variant	1	0.05	6e-06	5.22184874961636		1.35	[1.19-1.54]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2013-04-19	23326517	Holliday EG	2013-01-11	PLoS One	www.ncbi.nlm.nih.gov/pubmed/23326517	Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.	Age-related macular degeneration	3,772 European ancestry cases, 16,033 European ancestry controls	264 Asian ancestry cases, 3,926 Asian ancestry controls	19q13.32	19	44888997	APOE, PVRL2, TOMM40	NECTIN2, AC011481.2			ENSG00000130202, ENSG00000267282	NA	NA	rs6857-?	rs6857	0	6857	3_prime_UTR_variant	0	0.85	1e-06	6		1.23	[1.14-1.35]	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	1q25.1	1	173222336	TNFSF4	TNFSF4 - AL645568.3	ENSG00000117586	ENSG00000232751		15005	129353	rs2205960-A	rs2205960	0	2205960	intergenic_variant	1	0.27	3e-32	31.5228787452803		1.46	[1.37-1.56]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	5q33.1	5	151078585	TNIP1	TNIP1			ENSG00000145901	NA	NA	rs10036748-A	rs10036748	0	10036748	intron_variant	0	0.76	2e-09	8.69897000433602		1.23	[1.15-1.33]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	7p12.2	7	50266267	IKZF1	AC020743.2 - AC020743.3	ENSG00000231681	ENSG00000235620		3273	8523	rs4917014-A	rs4917014	0	4917014	regulatory_region_variant	1	0.68	3e-23	22.5228787452803		1.39	[1.30-1.47]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	8p23.1	8	11482672	BLK	AF131216.5 - BLK	ENSG00000284957	ENSG00000136573		1604	4222	rs7812879-G	rs7812879	0	7812879	regulatory_region_variant	1	0.76	2e-24	23.698970004336		1.45	[1.35-1.56]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	11q24.3	11	128441164	ETS1	LINC02098 - ETS1	ENSG00000272575	ENSG00000134954		199723	17597	rs6590330-A	rs6590330	0	6590330	intergenic_variant	1	0.34	2e-25	24.698970004336		1.37	[1.29-1.45]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	22q11.21	22	21562901	UBE2L3, HIC2	UBE2L3			ENSG00000185651	NA	NA	rs131654-A	rs131654	0	131654	intron_variant	0	0.48	1e-16	16		1.28	[1.20-1.35]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	16p11.2	16	30624338	NR	AC093249.5			ENSG00000261680	NA	NA	rs7186852-A	rs7186852	0	7186852	non_coding_transcript_exon_variant	0	0.08	3e-07	6.52287874528034		1.29	[1.17-1.42]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	6p21.32	6	32608701	HLA-DRB1	HLA-DRB1 - HLA-DQA1	ENSG00000206240	ENSG00000196735		18853	19478	rs9271100-?	rs9271100	0	9271100	intron_variant	1	NR	1e-12	12		1.9	[1.59-2.27]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	7q32.1	7	128933913	IRF5	AC025594.1 - IRF5	ENSG00000224163	ENSG00000128604		19850	3544	rs4728142-A	rs4728142	0	4728142	intergenic_variant	1	0.13	8e-19	18.0969100130081		1.43	[1.32-1.54]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	2p22.3	2	33476823	RASGRP3	RASGRP3			ENSG00000152689	NA	NA	rs13385731-A	rs13385731	0	13385731	intron_variant	0	0.85	1e-15	15		1.43	[1.32-1.56]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	2q32.2	2	191099907	STAT4	STAT4			ENSG00000138378	NA	NA	rs7574865-A	rs7574865	0	7574865	intron_variant	0	0.33	5e-42	41.301029995664		1.51	[1.43-1.61]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	6q21	6	106120159	PRDM1, ATG5	ATG5			ENSG00000057663	NA	NA	rs548234-G	rs548234	0	548234	intron_variant	0	0.26	5e-12	11.301029995664		1.25	[1.17-1.33]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	6q23.3	6	137874929	TNFAIP3	TNFAIP3			ENSG00000118503	NA	NA	rs2230926-C	rs2230926	0	2230926	missense_variant	0	0.04	1e-17	17		1.72	[1.52-1.94]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	10q11.23	10	48911009	LRRC18, WDFY4	LRRC18, AC060234.3, WDFY4			ENSG00000165383, ENSG00000241577, ENSG00000128815	NA	NA	rs1913517-A	rs1913517	0	1913517	intron_variant	0	0.29	7e-12	11.1549019599857		1.24	[1.17-1.32]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	11q23.3	11	118702810	NR	AP002954.1			ENSG00000255422	NA	NA	rs4639966-G	rs4639966	0	4639966	intron_variant	0	0.30	1e-16	16		1.29	[1.22-1.37]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	12q24.33	12	128816149	SLC15A4	SLC15A4			ENSG00000139370	NA	NA	rs1385374-A	rs1385374	0	1385374	intron_variant	0	0.20	2e-11	10.698970004336		1.26	[1.18-1.35]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	16p11.2	16	30631546	NR	AC093249.1 - PRR14	ENSG00000260113	ENSG00000156858		4368	19171	rs7197475-A	rs7197475	0	7197475	intergenic_variant	1	0.08	3e-08	7.52287874528034		1.31	[1.20-1.46]	Illumina [493955]	N
2009-11-09	19838193	Han JW	2009-10-18	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19838193	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.	Systemic lupus erythematosus	1,047 Han Chinese ancestry cases, 1,205 Han Chinese ancestry controls	3,152 Han Chinese ancestry cases, 7,050 Han Chinese ancestry controls	7q11.23	7	75543861	NR	HIP1			ENSG00000127946	NA	NA	rs1167796-G	rs1167796	0	1167796	intron_variant	0	0.71	2e-08	7.69897000433602		1.2	[1.12-1.28]	Illumina [493955]	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	6p21.1	6	41957421	BYSL, CCND3	CCND3			ENSG00000112576	NA	NA	rs9349205-A	rs9349205	0	9349205	intron_variant	0	NR	8e-20	19.0969100130081		0.01	[0.004-0.006] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	6q24.1	6	139517282	CITED2	AL592429.2			ENSG00000226571	NA	NA	rs628751-C	rs628751	0	628751	intron_variant	0	NR	1e-17	17		0	[0.003-0.005] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	22q12.3	22	37074184	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs2413450-T	rs2413450	0	2413450	intron_variant	0	NR	9e-34	33.0457574905607		0.01	[0.0005-0.007] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	3q29	3	196082268	TFRC	TFRC - LINC00885	ENSG00000072274	ENSG00000224652		172	60257	rs11915082-A	rs11915082	0	11915082	regulatory_region_variant	1	NR	8e-13	12.0969100130081		0	[0.003-0.005] pg increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	9p24.1	9	4856877	RCL1	RCL1			ENSG00000120158	NA	NA	rs10758658-A	rs10758658	0	10758658	intron_variant	0	NR	2e-14	13.698970004336		0	[0.004-0.006] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	19p13.13	19	12890733	GCDH	KLF1 - GCDH	ENSG00000105610	ENSG00000105607		3534	427	rs11085824-G	rs11085824	0	11085824	TF_binding_site_variant	1	NR	1e-11	11		0	[0.003-0.005] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	16p13.3	16	259156	ITFG3	FAM234A			ENSG00000167930	NA	NA	rs1122794-A	rs1122794	0	1122794	intron_variant	0	NR	3e-10	9.52287874528034		0	[0.003-0.006] pg increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	6q23.3	6	135097778	HBS1L, MYB	HBS1L			ENSG00000112339	NA	NA	rs7776054-G	rs7776054	0	7776054	intron_variant	0	NR	7e-69	68.1549019599858		0.01	[0.009-0.0111] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular hemoglobin	24,167 European ancestry individuals	9,456 European ancestry individuals	6p22.2	6	25842723	SLC17A3	SLC17A3			ENSG00000124564	NA	NA	rs1408272-G	rs1408272	0	1408272	intron_variant	0	NR	4e-39	38.397940008672		0.02	[0.01-0.02] pg decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	12q24.12	12	111634620	SH2B3, ATXN2	ATXN2-AS - BRAP	ENSG00000258099	ENSG00000089234		34364	7526	rs11065987-G	rs11065987	0	11065987	intergenic_variant	1	NR	1e-12	12		0.17	[0.12-0.22] % decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	7q22.1	7	100638347	TFR2	TFR2			ENSG00000106327	NA	NA	rs7385804-C	rs7385804	0	7385804	intron_variant	0	NR	4e-10	9.39794000867204		0.15	[0.10-0.20] % decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	7q36.1	7	151717955	PRKAG2	PRKAG2			ENSG00000106617	NA	NA	rs10224002-G	rs10224002	0	10224002	intron_variant	0	NR	6e-15	14.2218487496164		0.2	[0.15-0.25] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	10q22.1	10	69333636	HK1	HK1			ENSG00000156515	NA	NA	rs16926246-T	rs16926246	0	16926246	intron_variant	0	NR	1e-13	13		0.33	[0.24-0.42] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	2p21	2	46133768	PRKCE	PRKCE			ENSG00000171132	NA	NA	rs10168349-C	rs10168349	0	10168349	intron_variant	0	NR	4e-15	14.397940008672		0.19	[0.14-0.23] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	22q12.3	22	37074184	TMPRSS6	TMPRSS6			ENSG00000187045	NA	NA	rs2413450-T	rs2413450	0	2413450	intron_variant	0	NR	2e-13	12.698970004336		0.17	[0.13-0.22] % decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	6q23.3	6	135114363	HBS1L, MYB	HBS1L - MYB	ENSG00000112339	ENSG00000118513		11307	66945	rs9483788-C	rs9483788	0	9483788	intergenic_variant	1	NR	3e-15	14.5228787452803		0.22	[0.16-0.28] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Hematocrit	24,167 European ancestry individuals	9,456 European ancestry individuals	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	NR	2e-09	8.69897000433602		0.31	[0.21-0.41] % increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	6p22.2	6	26092913	HFE	HFE			ENSG00000010704	NA	NA	rs1800562-A	rs1800562	0	1800562	missense_variant	0	NR	1e-46	46		0.01	[0.010-0.014] fl increase	Affymetrix, Illumina [~ 2500000] (imputed)	N
2009-11-03	19862010	Ganesh SK	2009-10-11	Nat Genet	www.ncbi.nlm.nih.gov/pubmed/19862010	Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.	Mean corpuscular volume	24,167 European ancestry individuals	9,456 European ancestry individuals	6p21.1	6	41957421	BYSL, CCND3	CCND3			ENSG00000112576	NA	NA	rs9349205-A	rs9349205	0	9349205	intron_variant	0	NR	1e-31	31		0.01	[0.004-0.006] fl decrease	Affymetrix, Illumina [~ 2500000] (imputed)	N
