Package: M3Drop
Version: 1.22.0
Date: 2020-09-08
Title: Michaelis-Menten Modelling of Dropouts in single-cell RNASeq
Author: Tallulah Andrews <tallulandrews@gmail.com>
Maintainer: Tallulah Andrews <tallulandrews@gmail.com>
Depends: R (>= 3.4), numDeriv
Imports: RColorBrewer, gplots, bbmle, statmod, grDevices, graphics,
        stats, matrixStats, Matrix, irlba, reldist, Hmisc, methods
Suggests: ROCR, knitr, M3DExampleData, scater, SingleCellExperiment,
        monocle, Seurat, Biobase
VignetteBuilder: knitr
biocViews: RNASeq, Sequencing, Transcriptomics, GeneExpression,
        Software, DifferentialExpression, DimensionReduction,
        FeatureExtraction
Collate: basics.R Plotting_fxns.R Curve_fitting.R Extremes.R
        Normalization.R Brennecke_implementation.R
        Threeway_ProportionalArea_VennDiagrams.R
        Simulations_Functions.R Traditional_DE.R NB_UMI.R
        M3D_Imputation.R Other_FS_functions.R DANB_HVG.R
        DANB_Coexpression.R
Description: This package fits a Michaelis-Menten model to the pattern of dropouts in single-cell RNASeq data. This model is used as a null to identify significantly variable (i.e. differentially expressed) genes for use in downstream analysis, such as clustering cells. 
URL: https://github.com/tallulandrews/M3Drop
BugReports: https://github.com/tallulandrews/M3Drop/issues
License: GPL (>=2)
git_url: https://git.bioconductor.org/packages/M3Drop
git_branch: RELEASE_3_15
git_last_commit: 251aea9
git_last_commit_date: 2022-04-26
Date/Publication: 2022-04-26
NeedsCompilation: no
Packaged: 2022-04-26 23:18:52 UTC; biocbuild
Built: R 4.2.0; ; 2022-04-27 14:08:56 UTC; unix
