CalculateCSS {synergyfinder} | R Documentation

## Calculate Combination Sensitivity Score

### Description

This function will calculate the Combination Sensitivity Score (CSS) for a drug combination block.

### Usage

    CalculateCSS(response, ic50)

### Arguments

`response` | A data frame. It must contain the columns: "conc1", "conc2", ..., for the concentration of the combined drugs and "response" for the observed %inhibition at certain combination.
`ic50` | A list. It contains the relative IC50 for all the drugs in the combination.

### Value

A data frame. It contains the CSS for each drug will one of the other drugs is at its IC50 and summarized CSS for the whole block.

### Author(s)

- Shuyu Zheng shuyu.zheng@helsinki.fi

- Jing Tang jing.tang@helsinki.fi

[Package synergyfinder version 3.0.14 Index]