.ScoreCurve_L4 {synergyfinder} | R Documentation

## CSS Facilitate Function - .ScoreCurve for Curves Fitted by L.4 Model

### Description

This function is used to score sensitivities given either a single-agent or a fixed conc (combination) columns. The function calculates the AUC of the log10-scaled dose-response curve.

### Usage

    .ScoreCurve_L4(b, c, d, e, c1, c2, t)

### Arguments

`b` | A numeric value, fitted parameter b from `L.4` model.
`c` | A numeric value, fitted parameter c from `L.4` model.
`d` | A numeric value, fitted parameter d from `L.4` model.
`e` | A numeric value, fitted parameter e from `L.4` model.
`c1` | A numeric value, log10(min conc) (this is the minimal nonzero concentration).
`c2` | A numeric value, log10(max conc) (this is the maximal concentration).
`t` | A numeric value, threshold (usually set to zero).

### Value

A numeric value, RI or CSS scores.

### Author(s)

- Shuyu Zheng shuyu.zheng@helsinki.fi

- Jing Tang jing.tang@helsinki.fi

[Package synergyfinder version 3.0.14 Index]