.SolveLoewe {synergyfinder} | R Documentation

## Solve the Loewe Additive Effect for Concentration Combinations Isobologram

### Description

Solve the Loewe Additive Effect for Concentration Combinations Isobologram

### Usage

    .SolveLoewe(concs, drug_par, drug_type, nsteps = 100)

### Arguments

`concs` | A numeric vector. It contains the concentrations of tested drugs.
`drug_par` | A numeric vector. The parameters in fitted dose response curve.
`drug_type` | The type of model used to fit dose response curve.
`nsteps` | The total steps to calculate concentration combinations approaching to the true Loewe effect.

### Value

A list contains 3 items:

- y_loewe the predicted Loewe additive effect which closes to .

- x_select the expected concentrations for each drug to achieve y_loewe.

- distance the smallest distance

### Author(s)

- Shuyu Zheng shuyu.zheng@helsinki.fi

- Jing Tang jing.tang@helsinki.fi

[Package synergyfinder version 3.0.14 Index]