ONEIL_screening_data {synergyfinder} | R Documentation

## A high-throughput 2 drugs combination screening data with replication

### Description

A 2-drug combination screening data on cancer cell lines. It is from publication [(O'Neil, 2016)](https://pubmed.ncbi.nlm.nih.gov/26983881/). It contains 2 blocks, one is synergistic and the other is antagonistic.

### Format

A data frame with the following columns: "block_id", "drug1", "drug2", "cell_line_name", "conc1", "conc2", "response", "conc_unit1", "conc_unit2"

### References

O’Neil, J., Benita, Y., Feldman, I., Chenard, M., Roberts, B., Liu, Y., Li, J., Kral, A., Lejnine, S., Loboda, A., Arthur, W., Cristescu, R., Haines, B.B., Winter, C., Zhang, T., Bloecher, A., Shumway, S.D., 2016. An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies. Mol Cancer Ther 15, 1155–1162.

[Package synergyfinder version 3.0.14 Index]