stabilityRanking {staRank} | R Documentation

## Wrapper to perform stabilityRanking

### Description

An S4 function to perform stability ranking on a dataset or directly on given sample rankings.

### Arguments

`x` | the data that is to be ranked. It can be of different types: a data matrix with one row per element to be ranked, or a ranking from an external method, or an object of class cellHTS. Depending on this the other parameters can vary.
`samps` | a matrix of scored sample data, each row corresponds to an element, the columns to a scoring. This is only needed when an external ranking method is used.
`channel` | a string with the name of the feature (channel) to be ranked. This is only needed for cellHTS objects.
`replicates` | names or indices of the replicates (samples) to be used for the rankings (default: all samples are used).
`method` | one of the ranking methods: 'mean' (default), 'median', 'mwtest' (two-sample one sided Mann-Whitney test), 'ttest'(two-sample one sided t-test) or 'RSA' (redundant siRNA analysis). If an external ranking is used, you can specify the name of that ranking method in the method argument.
`decreasing` | a boolean indicating the direction of the ranking.
`bootstrap` | a boolean indicating if bootstrapping or subsampling is used.
`thr` | threshold for stability (default = 0.9).
`nSamp` | the number of samples to generate (default = 100).
`Pi` | boolean indicating if the Pi matrix should be returned (can be very large, default=FALSE).
`verbose` | boolean indicating if status update should be printed
`...` | further parameter for the stability ranking.

### Value

an object of class `RankSummary`.

### Examples

    # generate dataset
    d<-replicate(4,sample(1:10,10,replace=FALSE))
    rownames(d)<-letters[1:10]

    # rank aggregation on the dataset using two base methods
    aggregRank(d, method='mean')
    aggregRank(d, method='median')

    # calculate summary statistic from the data
    summaryStats(d, method='mean')
    summaryStats(d, method='RSA')

    # calculating replicate scores from different summary statistics
    scores<-getSampleScores(d,'mean',decreasing=FALSE,bootstrap=TRUE)
    scores<-getSampleScores(d,'mwtest',decreasing=FALSE,bootstrap=TRUE)

    # perform RSA analysis

    # get RSA format of data
    rsaData<-dataFormatRSA(d)
    # set RSA options
    opts<-list(LB=min(d),UB=max(d),reverse=FALSE)
    # run the RSA analysis
    r<-runRSA(rsaData,opts)
    # directly obtain the per gene RSA ranking from the data
    r<-uniqueRSARanking(rsaData,opts)

    # get stable Ranking, stable setsizes and the Pi matrix for default settings
    # and stability threshold of 0.9
    s<-getStability(d,0.9)

    # run default stability ranking
    s<-stabilityRanking(d)

    # using an accessor function on the RankSummary object
    stabRank(s)

    # summarize a RankSummary object
    summary(s)

    # generate a rank matrix from a RankSummary object
    getRankmatrix(s)

[Package staRank version 1.34.0 Index]