roar-package {roar} | R Documentation

## Identify differential APA usage from RNA-seq alignments

### Description

Identify preferential usage of APA sites, comparing two biological conditions, starting from known alternative sites and alignments obtained from standard RNA-seq experiments.

### Details

The codeRoarDataset class exposes methods to perform the whole analysis, in order to identify genes with preferential expression of long/short isoforms in a condition with respect to another one. The needed input data are alignments deriving from RNA-seq experiments of the two conditions and a set of coordinates of APA sites for genes with an alternative APA site proximal to the one used “normally”.

### Author(s)

Elena Grassi <grassi.e@gmail.com>

[Package roar version 1.28.0 Index]