edesignDR {maSigPro} | R Documentation

## Experimental design with different replicates

### Description

`edesignDR` contains experimental set up of a replicated time course microarray experiment where rats were submitted to 3 different dosis of a toxic compound. A control and an placebo treatments are also present in the experiment.

### Usage

    data(edesignDR)

### Format

A matrix with 54 rows and 7 columns

rows [1:54] "Array1" "Array2" "Array3" "Array4" ...

columns [1:7] "Time" "Replicates" "Control" "Placebo" "Low" "Medium" "High"

### Details

Arrays are given in rows and experiment descriptors are given in columns. Row names contain array names.

`"Time"` indicates the values that variable Time takes in each hybridization.

`"Replicates"` is an index indicating replicate hyridizations, i.e. hybridizations are numbered, giving replicates the same number.

`"Control"`, `"Placebo"`, `"Low"`, `"Medium"` and `"High"` columns indicate array assigment to experimental groups, coding with 1 and 0 whether each array belongs to that group or not.

### References

Heijne, W.H.M.; Stierum, R.; Slijper, M.; van Bladeren P.J. and van Ommen B.(2003). Toxicogenomics of bromobenzene hepatotoxicity: a combined transcriptomics and proteomics approach. Biochemical Pharmacology 65 857-875.

### Examples

    data(edesignDR)

[Package maSigPro version 1.64.0 Index]