calculateAdaptativeTrend {UMI4Cats} | R Documentation

## Adaptative smoothing of normalized trend

### Description

Will perform adaptative smoothing will scaling one profile to the reference UMI-4C profile.

### Usage

    calculateAdaptativeTrend(umi4c, sd = 2, normalized = TRUE)

### Arguments

`umi4c` | UMI4C object as generated by `makeUMI4C`.
`sd` | Stantard deviation for adaptative trend.
`normalized` | Logical indicating whether UMI-4C profiles should be normalized to the `ref_umi4c` sample/group. Default: TRUE

### Value

Calculates the adaptative trend considering the minimum number of molecules to use for merging different restriction fragments. It also calculates the geometric mean of the coordinates of the merged restriction fragments.

[Package UMI4Cats version 1.2.1 Index]