remove_homologous_interactions {STRINGdb} | R Documentation

## remove_homologous_interactions

### Description

With this method it is possible to remove the interactions that are composed by a pair of homologous/similar proteins, having a similarity bitscore between each other higher than a threshold.

### Usage

    ## S4 method for signature 'STRINGdb'
    remove_homologous_interactions(interactions_dataframe, bitscore_threshold = 60)

### Arguments

`interactions_dataframe` | a data frame contaning the sorted interactions to be benchmarked. The data frame should have the following column names: proteinA, proteinB, score
`bitscore_threshold` | filter out pairs of homologous proteins, having a similarity bitscore higher than this parameter

### Value

interactions data frame where the homologous pairs have been removed, from the input interactions' data frame

### Author(s)

Andrea Franceschini

[Package STRINGdb version 2.4.2 Index]