createDB {RCAS} | R Documentation

## createDB

### Description

Creates an sqlite database consisting of various tables of data obtained from processed BED files

### Usage

    createDB(
      dbPath = file.path(getwd(), "rcasDB.sqlite"),
      projDataFile,
      gtfFilePath = "",
      update = FALSE,
      genomeVersion,
      annotationSummary = TRUE,
      coverageProfiles = TRUE,
      motifAnalysis = TRUE,
      nodeN = 1
    )

### Arguments

`dbPath` | Path to the sqlite database file (could be an existing file or a new file path to be created at the given path)
`projDataFile` | A file consisting of meta-data about the input samples. Must minimally consist of two columns: 1. sampleName (name of the sample) 2. bedFilePath (full path to the location of the BED file containing data for the sample)
`gtfFilePath` | Path to the GTF file (preferably downloaded from the Ensembl database) that contains genome annotations
`update` | TRUE/FALSE (default: FALSE) whether an existing database should be updated
`genomeVersion` | A character string to denote for which genome version the analysis is being done. Available options are hg19/hg38 (human), mm9/mm10 (mouse), ce10 (worm) and dm3 (fly).
`annotationSummary` | TRUE/FALSE (default:TRUE) whether annotation summary module should be run
`coverageProfiles` | TRUE/FALSE (default: TRUE) whether coverage profiles module should be run
`motifAnalysis` | TRUE/FALSE (default: TRUE) whether motif discovery module should be run
`nodeN` | Number of cpus to use for parallel processing (default: 1)

### Value

Path to an SQLiteConnection object created by RSQLite package

### Examples

    FUS_path <- system.file("extdata", "FUS_Nakaya2013c_hg19.bed",
    package='RCAS')

    FMR1_path <- system.file("extdata",
    "FMR1_Ascano2012a_hg19.bed", package='RCAS')

    projData <- data.frame('sampleName' = c('FUS', 'FMR1'),
    'bedFilePath' = c(FUS_path,FMR1_path), stringsAsFactors = FALSE)

    write.table(projData, 'myProjDataFile.tsv', sep = '\t', quote =FALSE,
    row.names = FALSE)

    gtfFilePath <- system.file("extdata",
    "hg19.sample.gtf", package='RCAS')

    createDB(dbPath = 'hg19.RCASDB.sqlite',
    projDataFile = './myProjDataFile.tsv',
    gtfFilePath = gtfFilePath,
    genomeVersion = 'hg19',
    motifAnalysis = FALSE,
    coverageProfiles = FALSE)

    #Note: to add new data to an existing database, set update = TRUE

[Package RCAS version 1.18.0 Index]