avaSetFiltered_annot {R453Plus1Toolbox} | R Documentation

## AVASet variant annotations

### Description

These are example annotations for 4 variants of an AVASet (try `data(avaSetFiltered)` to retrieve the corresponding `link{AVASet-class}` object). The annotations include affected genes, exons and codons as well as resulting amino acid changes and dbSNP identifiers (if the mutation is already known).

### Usage

    data(avaSetFiltered_annot)

### Format

Formal class 'AnnotatedVariants'

### Source

‘Next-generation sequencing technology reveals a characteristic pattern of molecular mutations in 72.8% of chronic myelomonocytic leukemia by detecting frequent alterations in TET2, CBL, RAS, and RUNX1’ (Kohlmann A et al., J Clin Oncol. 2010 Aug 20;28(24):3858-65. Epub 2010 Jul 19)

### Examples

        data(avaSetFiltered_annot)

[Package R453Plus1Toolbox version 1.42.0 Index]