Package: PharmacoGx
Type: Package
Title: Analysis of Large-Scale Pharmacogenomic Data
Version: 2.4.0
Date: 2021-05-13
Authors@R: c(
  person("Petr", "Smirnov", email="petr.smirnov@uhnresearch.ca", role=c("aut")),
  person("Zhaleh", "Safikhani", role=c("aut")),
  person("Christopher", "Eeles", email="christopher.eeles@uhnresearch.ca", role=c("aut")),
  person("Mark", "Freeman", role=c("aut")),
  person("Benjamin", "Haibe-Kains", email="benjamin.haibe.kains@utoronto.ca", role=c("aut", "cre"))
  )
Description: Contains a set of functions to perform large-scale analysis of
    pharmaco-genomic data. These include the PharmacoSet object for storing
    the results of pharmacogenomic experiments, as well as a number of functions
    for computing common summaries of drug-dose response and correlating them
    with the molecular features in a cancer cell-line.
License: Artistic-2.0
Suggests: pander, rmarkdown, knitr, knitcitations, crayon, testthat,
        markdown
Encoding: UTF-8
Imports: BiocGenerics, Biobase, S4Vectors, SummarizedExperiment,
        MultiAssayExperiment, BiocParallel, ggplot2, magicaxis,
        RColorBrewer, parallel, caTools, methods, downloader, stats,
        utils, graphics, grDevices, reshape2, jsonlite, data.table,
        glue
Depends: R (>= 3.6), CoreGx
Roxygen: list(markdown = TRUE, r6=FALSE)
RoxygenNote: 7.1.1
VignetteBuilder: knitr
VignetteEngine: knitr::rmarkdown
biocViews: GeneExpression, Pharmacogenetics, Pharmacogenomics,
        Software, Classification
BugReports: https://github.com/bhklab/PharmacoGx/issues
Collate: 'ComputeGR.R' 'GR.R' 'GWC.R' 'LogLogisticRegression.R'
        'MatthewCor.R' 'allGenerics.R' 'PharmacoSet-class.R'
        'PharmacoSet-accessors.R' 'SanityCheck.R'
        'adaptiveMatthewCor.R' 'callingWaterfall.R'
        'class-SignatureClass.R' 'computeABC.R' 'computeAUC.R'
        'computeAUC_old.R' 'computeAmax.R' 'computeDSS.R'
        'computeDrugSensitivity.R' 'computeIC50.R' 'computeICn.R'
        'computeSlope.R' 'connectivityScore.R' 'cosinePerm.R'
        'datasets.R' 'downloadPSet.R' 'downloadSignatures.R'
        'drugDoseResponseCurve.R' 'drugPerturbationSig.R'
        'filterNoisyCurves.R' 'geneDrugPerturbation.R'
        'geneDrugSensitivity.R' 'getRawSensitivityMatrix.R' 'globals.R'
        'intersectPSets.R' 'methods-[.R' 'methods-drugSensitivitySig.R'
        'methods-intersect.R' 'methods-subsetTo.R'
        'methods-summarizeMolecularProfiles.R'
        'methods-summarizeSensitivityProfiles.R' 'plotPSig.R'
        'rankGeneDrugPerturbation.R' 'rankGeneDrugSensitivity.R'
git_url: https://git.bioconductor.org/packages/PharmacoGx
git_branch: RELEASE_3_13
git_last_commit: 1565ba6
git_last_commit_date: 2021-05-19
Date/Publication: 2021-05-19
NeedsCompilation: no
Packaged: 2021-05-20 01:36:47 UTC; biocbuild
Author: Petr Smirnov [aut],
  Zhaleh Safikhani [aut],
  Christopher Eeles [aut],
  Mark Freeman [aut],
  Benjamin Haibe-Kains [aut, cre]
Maintainer: Benjamin Haibe-Kains <benjamin.haibe.kains@utoronto.ca>
Built: R 4.1.0; ; 2021-05-20 09:25:00 UTC; windows
