hpo_download {OmnipathR} | R Documentation

## Downloads protein annotations from Human Phenotype Ontology

### Description

Human Phenotype Ontology (HPO) provides a standardized vocabulary of phenotypic abnormalities encountered in human disease. Each term in the HPO describes a phenotypic abnormality. HPO currently contains over 13,000 terms and over 156,000 annotations to hereditary diseases. See more at https://hpo.jax.org/app/.

### Usage

    hpo_download()

### Value

A tibble (data frame) of annotations as it is provided by the database

### Examples

    hpo_data <- hpo_download()
    hpo_data
    # # A tibble: 231,738 x 9
    #    entrez_gene_id entrez_gene_symb. hpo_term_id hpo_term_name
    #             <dbl> <chr>             <chr>       <chr>
    #  1           8192 CLPP              HP:0000013  Hypoplasia of the ute.
    #  2           8192 CLPP              HP:0004322  Short stature
    #  3           8192 CLPP              HP:0000786  Primary amenorrhea
    #  4           8192 CLPP              HP:0000007  Autosomal recessive i.
    #  5           8192 CLPP              HP:0000815  Hypergonadotropic hyp.
    # # . with 231,733 more rows, and 5 more variables:
    # #   frequency_raw <chr>, frequency_hpo <chr>, info_gd_source <chr>,
    # #   gd_source <chr>, disease_id <chr>

[Package OmnipathR version 3.0.0 Index]