ramilowski_download {OmnipathR} | R Documentation

## Downloads ligand-receptor interactions from Ramilowski et al. 2015

### Description

Curated ligand-receptor pairs from Supplementary Table 2 of the article "A draft network of ligand-receptor mediated multicellular signaling in human" (https://www.nature.com/articles/ncomms8866).

### Usage

    ramilowski_download()

### Value

A data frame (tibble) with interactions.

### Examples

    rami_interactions <- ramilowski_download()
    rami_interactions
    # # A tibble: 2,557 x 16
    #    Pair.Name Ligand.Approved. Ligand.Name Receptor.Approv.
    #    <chr>     <chr>            <chr>       <chr>
    #  1 A2M_LRP1  A2M              alpha-2-ma. LRP1
    #  2 AANAT_MT. AANAT            aralkylami. MTNR1A
    #  3 AANAT_MT. AANAT            aralkylami. MTNR1B
    #  4 ACE_AGTR2 ACE              angiotensi. AGTR2
    #  5 ACE_BDKR. ACE              angiotensi. BDKRB2
    # # . with 2,547 more rows, and 12 more variables: Receptor.Name <chr>,
    # #   DLRP <chr>, HPMR <chr>, IUPHAR <chr>, HPRD <chr>,
    # #   STRING.binding <chr>, STRING.experiment <chr>, HPMR.Ligand <chr>,
    # #   HPMR.Receptor <chr>, PMID.Manual <chr>, Pair.Source <chr>,
    # #   Pair.Evidence <chr>

[Package OmnipathR version 3.0.0 Index]