filter_exp_by_quant_mean_FC {MethReg} | R Documentation

## Select genes with variations above a threshold

### Description

For each gene, compares the mean gene expression levels in samples in high expression (Q4) vs. samples with low gene expression (Q1), and requires the fold change to be above a certain threshold.

### Usage

    filter_exp_by_quant_mean_FC(exp, fold.change = 1.5, cores = 1)

### Arguments

`exp` | Gene expression matrix or SumarizedExperiment object
`fold.change` | Threshold for fold change of mean gene expression levels in samples with high (Q4) and low (Q1) gene expression levels. Defaults to 1.5.
`cores` | Number of CPU cores to be used in the analysis. Default: 1

### Value

A subset of the original matrix only with the rows passing the filter threshold.

### Examples

    data("gene.exp.chr21.log2")
    gene.exp.chr21.log2.filtered <- filter_exp_by_quant_mean_FC(
      gene.exp.chr21.log2
    )

[Package MethReg version 1.2.1 Index]