GenoGAM {GenoGAM} | R Documentation

## GenoGAM: A package providing a framework to analyse ChIP-Seq data

### Description

This package allows statistical analysis of genome-wide data with smooth functions using generalized additive models based on the implementation from the R-package 'mgcv'. It provides methods for the statistical analysis of ChIP-Seq data including inference of protein occupancy, and pointwise and region-wise differential analysis. Estimation of dispersion and smoothing parameters is performed by cross-validation. Scaling of generalized additive model fitting to whole chromosomes is achieved by parallelization over overlapping genomic intervals.

### Author(s)

Maintainer: Georg Stricker georg.stricker@in.tum.de

Authors:

- Alexander Engelhardt alexander.engelhardt@ibe.med.uni-muenchen.de

- Julien Gagneur gagneur@in.tum.de

### See Also

Useful links:

- https://github.com/gstricker/GenoGAM

- Report bugs at https://github.com/gstricker/GenoGAM/issues

[Package GenoGAM version 2.10.0 Index]