DSS-package {DSS} | R Documentation

## Dispersion shrinkage for sequencing data

### Description

DSS is an R library performing the differential expression analysis for RNA-seq count data. Compared with other similar packages (DESeq, edgeR), DSS implements a new dispersion shrinkage method to estimate the gene-specific biological variance. Extensive simulation results showed that DSS performs favorabily compared to DESeq and edgeR when the variation of biological variances is large.

DSS only works for two group comparison at this time. We plan to extend the functionalities and make it work for more general experimental designs in the near future.

### Author(s)

Hao Wu <hao.wu@emory.edu>

[Package DSS version 2.40.0 Index]