get_HK {BioNERO} | R Documentation

## Get housekeeping genes from global expression profile

### Description

Get housekeeping genes from global expression profile

### Usage

    get_HK(exp)

### Arguments

`exp` | A gene expression data frame with genes in row names and samples in column names or a 'SummarizedExperiment' object.

### Details

This function identifies housekeeping genes, which are broadly expressed genes with low variation in a global scale across samples. For some cases, users would want to remove these genes as they are not interesting for coexpression network analyses. See references for more details.

### Value

Character vector of housekeeping gene IDs.

### Author(s)

Fabricio Almeida-Silva

### References

Machado, F.B., Moharana, K.C., Almeida‐Silva, F., Gazara, R.K., Pedrosa‐Silva, F., Coelho, F.S., Grativol, C. and Venancio, T.M. (2020), Systematic analysis of 1298 RNA‐Seq samples and construction of a comprehensive soybean (Glycine max) expression atlas. Plant J, 103: 1894-1909.

### Examples

    data(zma.se)
    hk <- get_HK(zma.se)

[Package BioNERO version 1.0.4 Index]