rituximab {flowClust} | R Documentation

## The Rituximab Dataset

### Description

A flow cytometry dataset produced in a drug-screening project to identify agents that would enhance the anti-lymphoma activity of Rituximab, a therapeutic monoclonal antibody. Cells were stained with anti-BrdU FITC and the DNA binding dye 7-AAD.

### Format

An object of class `flowFrame` with 1545 cells (rows) and the following eight variables (columns):

FSC.H

  FSC-Height

SSC.H

  Side Scatter

FL1.H

  Anti-BrdU FITC

FL2.H

  Channel not used

FL3.H

  7 AAD

FL1.A

  Channel not used

FL1.W

  Channel not used

Time

  Time

### Source

Gasparetto, M., Gentry, T., Sebti, S., O'Bryan, E., Nimmanapalli, R., Blaskovich, M. A., Bhalla, K., Rizzieri, D., Haaland, P., Dunne, J. and Smith, C. (2004) Identification of compounds that enhance the anti-lymphoma activity of rituximab using flow cytometric high-content screening. J. Immunol. Methods 292, 59-71.

[Package flowClust version 3.28.0 Index]