mm_mRNA {TimiRGeN} | R Documentation

## Mouse microRNA data

### Description

Mouse Fibrosis mRNA data from differential expression analysis. Folic Acid was injected into mouse kidneys to induce fibrosis and nephropathy. Measurements were taken prior to and 1, 2, 3, 7 and 14 days after injection. The 0 time point was contrasted over other time points. Data was put through limma for analysis. mm_mRNA only has DE results from 2000 mRNA genes for speed and size optimisation.

Column names are in the following format: timepoint(days).DEresult (Log2FC or adjPVal).

### Usage

    data("mm_mRNA")

### Format

A data frame of mRNAs put through differential expression with 2000 observations in the following 10 variables.

`D1.Log2FC`

  a numeric vector containing log2FC values of D1_fibrosis/ D0_fibrosis.

`D1.adjPVal`

  a numeric vector containing adjusted P values of D1_fibrosis/ D0_fibrosis.

`D2.Log2FC`

  a numeric vector containing log2FC values of D2_fibrosis/ D0_fibrosis.

`D2.adjPVal`

  a numeric vector containing adjusted P values of D2_fibrosis/ D0_fibrosis.

`D3.Log2FC`

  a numeric vector containing log2FC values of D3_fibrosis/ D0_fibrosis.

`D3.adjPVal`

  a numeric vector containing adjusted P values of D3_fibrosis/ D0_fibrosis.

`D7.Log2FC`

  a numeric vector containing log2FC values of D7_fibrosis/ D0_fibrosis.

`D7.adjPVal`

  a numeric vector containing adjusted P values of D7_fibrosis/ D0_fibrosis.

`D14.Log2FC`

  a numeric vector containing log2FC values of D14_fibrosis/ D0_fibrosis.

`D14.adjPVal`

  a numeric vector containing adjusted P values of D14_fibrosis/ D0_fibrosis.

### Source

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE613287

### References

M. Pavkovic, L. Pantano, C. V. Gerlach, S. Brutus, S. A. Boswell, R. A. Everley, J. V. Shah, S. H. Sui, and V. S. Vaidya, “Multi omics a nalysis of fibrotic kidneys in two mouse models,” Scientific data, vol. 6, no. 1, p. 92, 2019. <https://www.nature.com/articles/s41597-019-0095-5>

### Examples

    data(mm_mRNA)
    ## maybe str(mm_mRNA) ; plot(mm_mRNA) ...

[Package TimiRGeN version 1.0.6 Index]