sigInteractorsDIGGIT {MOMA} | R Documentation

## Filter interactions from NES (DIGGIT) scores and corresponding background-corrected scores.

### Description

Use this version in the Bayes model to rank TFs

### Usage

    sigInteractorsDIGGIT(
      corrected.scores,
      nes.scores,
      cindy,
      p.thresh = 0.05,
      cindy.only = TRUE
    )

### Arguments

`corrected.scores` | A list indexed by the genomic event/gene with corresponding pvals and qvals for each TF
`nes.scores` | Matrix with tfs as columns, rows are genomic events
`cindy` | CINDy algorithm output matrix
`p.thresh` | P-value threshold (default=0.05)
`cindy.only` | Consider only CINDy validated interactions (default=TRUE)

### Value

a list (indexed by VIPER protein) of significant genomic interactions and associated pvals over the background (null TF) model, and NES scores

[Package MOMA version 1.2.0 Index]