.topo_ic_sim_titj {GAPGOM} | R Documentation

## GAPGOM internal - .topo_ic_sim_titj()

### Description

This function is an internal function and should not be called by the user.

### Usage

    .topo_ic_sim_titj(go_id1, go_id2, topoargs)

### Arguments

`go_id1` | GO term of first term.
`go_id2` | GO term of second term.
`topoargs` | list containing all the neccesary paramters/arguments for the topoicsim algorithm, details can be view in the ".prepare_variables_topoicsim" function.

### Details

Algorithm to calculate similarity between two GO terms. This function is made for calculating topological similarity of two GO terms in the GO DAG structure. The topological similarity is based on edge weights and information content (IC). [1]

### Value

semantic topological similarity between the two given go terms.

### Notes

Internal function used in (topo_ic_sim_term()).

### References

[1] Ehsani R, Drablos F: TopoICSim: a new semantic similarity measure based on gene ontology. BMC Bioinformatics 2016, 17(1):296)

[Package GAPGOM version 1.6.0 Index]