segmentSamplesUsingPopInformation {CNVrd2} | R Documentation

## Implement the segmentation process for multiple populations

### Description

Segment read-count windows into region having similar signal values by using the DNAcopy package (Venkatraman and Olshen, 2007) and refine this process to obtain segmentation scores at genes. Then, the function adjusts segmentation scores for multiple populations using a linear regression model.

### Usage

    segmentSamplesUsingPopInformation(Object, ...)

### Arguments

`Object` | An object of class CNVrd2.
`...` | Optional arguments.

### Value

`segmentationScores` | All adjusted results of the segmentation process.
`segmentationScoresFromSinglePops` | Segmentation scores of single populations.
`segmentResults` | Un-adjusted segmentation scores
`observedReadCountRatios` | Observed read-count ratios of genes. This value is a matrix of observed read-count ratios at genes if (only inputBamFile = TRUE).
`stdCntMatrix` | Matrix of read counts (standardized).

### Author(s)

Hoang Tan Nguyen, Tony R Merriman and MA Black. hoangtannguyenvn@gmail.com

### References

Venkatraman, E., Olshen, A. B., 2007. A faster circular binary segmentation algorithm for the analysis of array chg data. Bioinformatics 23 (6), 657-663.

### See Also

`countReadInWindow`, `DNAcopy`

[Package CNVrd2 version 1.28.0 Index]