rrbs {BiSeq} | R Documentation

## RRBS data of APL patient samples and controls.

### Description

RRBS data of the CpG sites CpG sites from genomic regions on p arms of chromosome 1 and 2 covered in at least one sample. Data was obtained from 5 APL patient samples and 5 control samples (APL in remission). RRBS data was preprocessed with the Bismark software version 0.5.

### Usage

    rrbs

### Format

A `BSraw-class` object.

### Source

Schoofs T, Rohde C, Hebestreit K, Klein HU, Goellner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Buechner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Mueller-Tidow C (2012). DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding. Blood.

### References

Krueger F, Andrews SR. Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications. Bioinformatics. 2011;27:1571-1572.

### Examples

    data(rrbs)
    show(rrbs)

[Package BiSeq version 1.30.0 Index]