Package: gCrisprTools
Type: Package
Title: Suite of Functions for Pooled Crispr Screen QC and Analysis
Version: 1.18.0
Date: 2019-04-09
Author: Russell Bainer, Dariusz Ratman, Steve Lianoglou, Peter Haverty
Authors@R: c(
    person("Russell", "Bainer", , "russ.bainer@gmail.com", c("aut", "cre")),
    person("Dariusz", "Ratman", , "ratmand@roche.com", "aut"),
    person("Peter", "Haverty", , "havertypm@gmail.com", "aut"),
    person("Steve", "Lianoglou", , "slianoglou@gmail.com", "aut"),
    person("Maze Therapeutics", role = c("fnd"), comment = "2019+"),
    person("Genentech, Inc.", role = c("fnd"), comment = "2014 - 2018"))
Maintainer: Russell Bainer <russ.bainer@gmail.com>
Description: Set of tools for evaluating pooled high-throughput screening experiments,
    typically employing CRISPR/Cas9 or shRNA expression cassettes. Contains methods for interrogating
    library and cassette behavior within an experiment, identifying differentially abundant
    cassettes, aggregating signals to identify candidate targets for empirical validation,
    hypothesis testing, and comprehensive reporting.
License: Artistic-2.0
Imports: Biobase, limma, RobustRankAggreg, ggplot2, PANTHER.db,
        rmarkdown, grDevices, graphics, stats, utils, parallel,
        SummarizedExperiment
Suggests: edgeR, knitr, grid, AnnotationDbi, org.Mm.eg.db,
        org.Hs.eg.db, RUnit, BiocGenerics
RoxygenNote: 7.1.0
VignetteBuilder: knitr
Encoding: UTF-8
biocViews: ImmunoOncology, CRISPR, PooledScreens, ExperimentalDesign,
        BiomedicalInformatics, CellBiology, FunctionalGenomics,
        Pharmacogenomics, Pharmacogenetics, SystemsBiology,
        DifferentialExpression, GeneSetEnrichment, Genetics,
        MultipleComparison, Normalization, Preprocessing,
        QualityControl, RNASeq, Regression, Software, Visualization
NeedsCompilation: no
Depends: R (>= 3.6)
git_url: https://git.bioconductor.org/packages/gCrisprTools
git_branch: RELEASE_3_12
git_last_commit: e6168b2
git_last_commit_date: 2020-10-27
Date/Publication: 2020-10-27
Packaged: 2020-10-28 00:16:07 UTC; biocbuild
Built: R 4.0.3; ; 2020-10-28 13:20:58 UTC; unix
