noobsb {sesame} | R Documentation

## Background subtraction with bleeding-through subtraction

### Description

The function takes a `SigSet` and returns a modified `SigSet` with background subtracted. Signal bleed-through was modelled using a linear model with error estimated from cross-channel regression. Norm-Exp deconvolution using Out-Of-Band (oob) probes.

### Usage

    noobsb(sset, offset = 15, detailed = FALSE)

### Arguments

`sset` | a `SigSet`
`offset` | offset
`detailed` | if TRUE, return a list of `SigSet` and regression function

### Value

a modified `SigSet` with background correction

### Examples

    sset <- makeExampleSeSAMeDataSet('HM450')
    sset.nb <- noobsb(sset)

[Package sesame version 1.5.3 Index]