create_sd_matrix {scsR} | R Documentation

## create_sd_matrix

### Description

We observed that the standard deviation of the oligos that share the same seed do change relative to their average score. In principle we could plot this information on a graph (x-axis = average of the oligos that share the same seed, y-axes = standard deviation of the oligos). We do provide this utility method to condense this information in a matrix (that reports the quantiles of the standard deviation for every score interval).

### Usage

    create_sd_matrix(screen, seedColName="seed7", scoreColName="score")

### Arguments

`screen` | data frame containing the results of the siRNA experiment.
`seedColName` | name of the column that contains the seeds sequences of the screen (character vector)
`scoreColName` | name of the column that contains the score of the screen (character vector)

### Value

matrix that reports the quantiles of the standard deviation for every score interval.

### Author(s)

Andrea Franceschini

### Examples

    	data(uuk_screen)

    	# to speed up the example we use only the first 100 rows
    	uuk_screen_reduced = uuk_screen[1:100,]

    	screen = add_seed(uuk_screen_reduced)
    	sd_matrix = create_sd_matrix(screen)

[Package scsR version 1.23.0 Index]