PoolScreenExp-class {gscreend} | R Documentation

## Class to store pooled CRISPR screening experiment

### Description

The `poolScreenExp` class is an S4 class used to store sgRNA and gene related data as well as parameters necessary for statistical model.

### Slots

`sgRNAData`

  A SummarizedExperiment containing the data related to sgRNAs.

`FittingIntervals`

  A vector defining the limits of the intervals used for fitting of null model.

`LFCModelParameters`

  A vector of parameters estimated when fitting the null model.

`GeneData`

  SummarizedExperiment containing the data related to genes.

`FittingOptions`

  A named list with options for fitting: IntervalFraction - fraction of sgRNAs used in every fitting interval (default 0.1), alphaCutoff - alpha cutoff for alpha RRA algorithm (default: 0.05).

[Package gscreend version 1.1.0 Index]