clean_profile {PrInCE} | R Documentation

## Preprocess a co-elution profile

### Description

Clean a co-elution/co-fractionation profile by (1) imputing single missing values with the average of neighboring values, (2) replacing missing values with random, near-zero noise, and (3) smoothing with a moving average filter.

### Usage

    clean_profile(chromatogram, impute_NA = TRUE, smooth = TRUE,
      smooth_width = 4, noise_floor = 0.001)

### Arguments

`chromatogram` | a numeric vector corresponding to the chromatogram trace
`impute_NA` | if true, impute single missing values with the average of neighboring values
`smooth` | if true, smooth the chromatogram with a moving average filter
`smooth_width` | width of the moving average filter, in fractions
`noise_floor` | mean value of the near-zero noise to add

### Value

a cleaned profile

### Examples

    data(scott)
    chrom <- scott[16, ]
    cleaned <- clean_profile(chrom)

[Package PrInCE version 1.3.0 Index]