ResembleDepmap {MAGeCKFlute} | R Documentation

## Compute the similarity between customized CRISPR screen with Depmap screens

### Description

Compute the similarity between customized CRISPR screen with Depmap screens

### Usage

    ResembleDepmap(
      dd,
      symbol = "id",
      score = "Score",
      lineages = "All",
      method = c("pearson", "spearman", "kendall")[1]
    )

### Arguments

`dd` | A data frame.
`symbol` | A character, specifying the column name of gene symbols in the data frame.
`score` | A character, specifying the column name of gene essentiality score in the data frame.
`lineages` | A character vector, specifying the lineages used for common essential gene selection.
`method` | A character, indicating which correlation coefficient is to be used for the test. One of "pearson", "kendall", or "spearman".

### Value

A data frame with correlation and test p.value.

### Author(s)

Wubing Zhang

### Examples

    file1 = file.path(system.file("extdata", package = "MAGeCKFlute"),
    "testdata/rra.gene_summary.txt")
    gdata = ReadRRA(file1)
    ## Not run:
      rra.omit = OmitCommonEssential(gdata)
      depmap_similarity = ResembleDepmap(rra.omit)
      head(depmap_similarity)

    ## End(Not run)

[Package MAGeCKFlute version 1.7.2 Index]