MFAParams {splatter} | R Documentation

## The MFAParams class

### Description

S4 class that holds parameters for the mfa simulation.

### Parameters

The mfa simulation uses the following parameters:

`nGenes`

  The number of genes to simulate.

`nCells`

  The number of cells to simulate.

`[seed]`

  Seed to use for generating random numbers.

`[trans.prop]`

  Proportion of genes that show transient expression. These genes are briefly up or down-regulated before returning to their initial state

`[zero.neg]`

  Logical. Whether to set negative expression values to zero. This will zero-inflate the data.

`[dropout.present]`

  Logical. Whether to simulate dropout.

`dropout.lambda`

  Lambda parameter for the exponential dropout function.

The parameters not shown in brackets can be estimated from real data using `mfaEstimate`. See `create_synthetic` for more details about the parameters. For details of the Splatter implementation of the mfa simulation see `mfaSimulate`.

[Package splatter version 1.12.0 Index]