drugDB {rcellminer} | R Documentation

## CellMiner Drug Response Values

### Description

CellMiner Drug Response Values

### Details

A list containing response values and annotations:

- act Z-scores of the averaged negative log GI (growth inhibition) 50 values across repeats for the NCI-60; assay described here: http://dtp.nci.nih.gov/branches/btb/ivclsp.html

- annot

  - id Dataset identifier; NOTE: DO NOT use this column; the NSC is the primary drug identifier

  - nsc National Service Center identifier; the primary drug identifier

  - name Compound name

  - brand_name Brand name for the compound, if sold commericially

  - formula Compound chemical formula

  - testing_status Information on whether it is known if the compound is FDA approved or undergoing testing in clinical trials

  - source TODO

  - smiles Compound chemical structure as a SMILES string

  - weight Compound chemical weight in g/mol

  - mechanism Pharmacological mechanism of action

  - confidential_flag A flag to indicate if compound information is public

  - total_probes TODO

  - total_good_probes TODO

  - low_correlations TODO

  - failure_reason TODO

  - cas CAS Registry Number; NOTE: Due to data restrictions PubChem IDs are the preferred mapping ID to other datasets

  - pubchem_id PubChem ID

### Author(s)

Vinodh Rajapakse vinodh.rajapakse AT nih.gov

### References

http://discover.nci.nih.gov/cellminer/loadDownload.do

[Package rcellminer version 2.10.2 Index]