annotateRegions {derfinder} | R Documentation

## Assign genomic states to regions

### Description

This function takes the regions found in calculatePvalues and assigns them genomic states contructed with makeGenomicState. The main workhorse functions are countOverlaps and findOverlaps.

### Usage

    annotateRegions(regions, genomicState, annotate = TRUE, ...)

### Arguments

`regions` | The `$regions` output from calculatePvalues.
`genomicState` | A GRanges object created with makeGenomicState. It can be either the `genomicState$fullGenome` or `genomicState$codingGenome` component.
`annotate` | If `TRUE` then the regions are annotated by the genomic state. Otherwise, only the overlaps between the regions and the genomic states are computed.
`...` | Arguments passed to other methods and/or advanced arguments. Advanced arguments: verbose If `TRUE` basic status updates will be printed along the way. ignore.strand Passed on to findOverlaps-methods and countOverlaps. Default: `TRUE`. Passed to extendedMapSeqlevels, countOverlaps and findOverlaps-methods.

### Details

You might want to specify arguments such as `minoverlap` to control how the overlaps are determined. See findOverlaps for further details.

### Value

A list with elements `countTable` and `annotationList` (only if `annotate=TRUE`).

countTable

  This is a data.frame with the number of overlaps from the regions vs the genomic states with one type per column. For example, if `fullOrCoding='full'` then the columns are `exon`, `intergenic` and `intron`.

annotationList

  This is a `GRangesList` with the genomic states that overlapped with the regions. The names of this `GRangesList` correspond to the region index in `regions`.

### Author(s)

Andrew Jaffe, Leonardo Collado-Torres

### See Also

makeGenomicState, calculatePvalues

### Examples

    ## Annotate regions, first two only
    annotatedRegions <- annotateRegions(
        regions = genomeRegions$regions[1:2],
        genomicState = genomicState$fullGenome, minoverlap = 1
    )
    annotatedRegions

[Package derfinder version 1.22.0 Index]