tpp2dMerge2dRef {TPP} | R Documentation

## Merge 2D-TPP result data with TPP-TR reference data

### Description

Merges 2D-TPP result data with TPP-TR reference data to generate a big table including both results

### Usage

    tpp2dMerge2dRef(
      resultTable_2D,
      referenceDataSummary,
      refIDVar = "Protein_ID",
      idVar = NULL,
      data = NULL,
      trRef = NULL
    )

### Arguments

`resultTable_2D` | dataframe containing the 2D-TPP results
`referenceDataSummary` | summarized reference data results. See details.
`refIDVar` | character string indicating name of the columns containing the unique protein identifiers in the reference data set
`idVar` | DEPRECATED
`data` | DEPRECATED
`trRef` | DEPRECATED

### Details

`referenceSummary` contains summary statistics like median fold changes and is produced by the function `tpp2dCreateTPPTRreference`. It summarizes the results of a TPP-TR analysis of a reference data set. A reference data set is the a output of a TR experiment without drug treatment on the same cell line as resultTable_2D.

### Value

A data frame with results merged from 2D-TPP and TPP-TR reference

### See Also

`tpp2dCreateTPPTRreference`

### Examples

    data(panobinostat_2DTPP_smallExample)
    config_tpp2d <- panobinostat_2DTPP_config
    data_tpp2d <- panobinostat_2DTPP_data
    tpp2dResults <- analyze2DTPP(configTable = config_tpp2d,
                                 data = data_tpp2d,
                                 methods=c("doseResponse"),
                                 createReport="none",
                                 nCores=1,
                                 idVar = "representative",
                                 addCol = "clustername",
                                 intensityStr = "sumionarea_protein_",
                                 nonZeroCols = "qusm")

    trRef <- file.path(system.file("data", package="TPP"),
    "TPPTR_reference_results_HepG2.RData")

    annotatedTable <- tpp2dMerge2dRef(resultTable_2D = tpp2dResults,
                                      referenceDataSummary = trRef)

[Package TPP version 3.16.5 Index]