test2Interact {SLGI} | R Documentation

## Summarize genetic interactions within or between cellular organizational units

### Description

Summarize the genetic interactions within one cellular organizational unit or between 2 cellular organizational units.

### Usage

    test2Interact(iMat, tMat, interactome)

### Arguments

`iMat` | Genetic interaction matrix. Each entry has value 0 or 1, representing positive or negative interaction of corresponding pairs of row and column, respectively.
`tMat` | Adjacency matrix of tested object. Each entry has value 0 or 1, representing the fact that the corresponding pairs of row and column have been tested for interaction or not.
`interactome` | Adjacency matrix where row are gene names and columns are cellular organizational units names. Each entry has value 0 or 1, for absence or presence of a gene in the complex.

### Value

the return value is a data.frame with 6 columns.

`unit1, unit2` | cellular organizational units tested and interacting
`tested` | Number of interactions tested between unit1 and unit2
`interact` | Number of interactions found between unit1 and unit2
`sizeC1, sizeC2` | Number of genes in unit1 and unit2

### Author(s)

N. LeMeur

### Examples

    set.seed(123)
    ##Create the interactome
    cInt <- sample(c(0,1),30, TRUE)
    interactome  <- matrix(cInt, nrow=6, ncol=5,dimnames=list(letters[2:7],LETTERS[1:5]))

    ## Create cellular organizational units interaction matrix
    gInt <- sample(c(1:8), 25, TRUE)
    gInt  <- matrix(gInt, nrow=5, ncol=5, dimnames=list(LETTERS[1:5],LETTERS[1:5]))

    ## All interactome tested
    gTest <- matrix(sample(c(0:3), 25, TRUE), nrow=5, ncol=5)
    gTested <- gInt+gTest

    val <- test2Interact(iMat=gInt, tMat=gTested, interactome=interactome)

[Package SLGI version 1.48.0 Index]