PrecisionTrialDrawer-package {PrecisionTrialDrawer} | R Documentation

## PrecisionTrialDrawer: a package to analyze and design custom cancer panels

### Description

PrecisionTrialDrawer is a package that a allows the design and study of a cancer panel to create pilot sets for a clinical trial.

### Details

It allows simulations on real TCGA data to design a possible clinical trial, both as basket or umbrella design.

Furthermore, it can provide an easy function to calculate genomic space occupied by the cancer panel in a commonly used bed format ready to be submitted to a NGS company.

### Author(s)

Giorgio Melloni, Alessandro Guida

### References

Cbioportal web site MD Anderson TCGA Fusion Portal

### Examples

    # Retrieve a Cancer Panel
    data(cpObj)
    # Show the number of covered samples
    coveragePlot(cpObj
                , alterationType=c("mutations" , "copynumber")
                , grouping=c("group" , "tumor_type"))

[Package PrecisionTrialDrawer version 1.4.0 Index]