Package: LACE
Version: 1.0.0
Date: 2020-04-25
Title: Longitudinal Analysis of Cancer Evolution (LACE)
Authors@R: c(person("Daniele","Ramazzotti",role=c("aut"),email="daniele.ramazzotti@unimib.it"),
    person("Fabrizio","Angaroni",role=c("aut"),email="fabrizio.angaroni@unimib.it"),
    person("Davide","Maspero",role=c("cre","aut"),email="d.maspero@campus.unimib.it"),
    person("Alex","Graudenzi",role=c("aut"),email="alex.graudenzi@unimib.it"))
Depends: R (>= 4.0.0)
Imports: graphics, grDevices, igraph, parallel, RColorBrewer, Rfast,
        stats, SummarizedExperiment, utils
Suggests: BiocGenerics, BiocStyle, testthat, knitr
Name: LACE: an R package for the inference of longitudinal cancer
        evolution models
Description: 
    LACE is an algorithmic framework that processes single-cell somatic mutation profiles from cancer samples collected at different time points and in distinct experimental settings, to produce longitudinal models of cancer evolution. The approach solves a Boolean Matrix Factorization problem with phylogenetic constraints, by maximizing a weighed likelihood function computed on multiple time points. 
Encoding: UTF-8
LazyData: TRUE
License: file LICENSE
URL: https://github.com/BIMIB-DISCo/LACE
BugReports: https://github.com/BIMIB-DISCo/LACE
biocViews: BiomedicalInformatics, SingleCell, SomaticMutation
RoxygenNote: 7.1.0
VignetteBuilder: knitr
git_url: https://git.bioconductor.org/packages/LACE
git_branch: RELEASE_3_11
git_last_commit: 67c3e1a
git_last_commit_date: 2020-04-27
Date/Publication: 2020-04-27
NeedsCompilation: no
Packaged: 2020-04-28 07:39:02 UTC; biocbuild
Author: Daniele Ramazzotti [aut],
  Fabrizio Angaroni [aut],
  Davide Maspero [cre, aut],
  Alex Graudenzi [aut]
Maintainer: Davide Maspero <d.maspero@campus.unimib.it>
Built: R 4.0.0; ; 2020-04-28 18:22:42 UTC; windows
