combineProfiles {DrugVsDisease} | R Documentation

## Combine Profiles

### Description

Combine a set of hybridisations using the median rank method as proposed by Warnat

### Usage

    combineProfiles(data)

### Arguments

`data` | A list of R objects, each object should contain a matrix of expression values to be merged with each other. The first object will be used as the reference data set.

### Details

The combine profiles function merges a set of expression values, normalising across different experiments to facilitate the meta-analysis of similar experiments i.e. cell lines treated with the same drug but which may be from different "batches" or platforms.

### Value

Matrix of rank normalised expression data. Rows are genes, columns are hybridisations from the different experiments.

### Author(s)

C. Pacini

### References

R code from CONOR package. Need also reference to the method.

[Package DrugVsDisease version 2.30.0 Index]