# A correction of the local pooled error (LPE) method to replace the asymptotic variance adjustment with an unbiased adjustment based on sample size.

## Documentation for package ‘LPEadj’ version 1.26.0

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

adjBaseOlig.error | Evaluates LPE variance function of M for quantiles of A within and experimental condition and then interpolates it for all genes.
adjBaseOlig.error.step1 | Evaluates LPE variance function of M for quantiles of A within and experimental condition by dividing the A in 100 intervals.
adjBaseOlig.error.step2 | Evaluates LPE variance function of M for quantiles of A within and experimental condition. It is based on the adaptive number of intervals.
calculateLpeAdj | Evaluates local pooled error significance test with user chosen variance adjustments.
lpeAdj | High level lpeAdj function that executes the adjusted local pooled error significance test. If more control over parameters is needed then see documentation for calculateLpeAdj.