colorectalcancer            package:SPIA            R Documentation

_R_e_s_u_l_t_s _f_r_o_m _a _m_i_c_r_o_a_r_r_a_y _e_x_p_r_i_m_e_n_t _c_o_m_p_a_r_i_n_g _c_o_l_o_r_e_c_t_a_l _c_a_n_c_e_r _s_a_m_p_l_e_s _a_n_d _n_o_r_m_a_l _t_i_s_s_u_e _s_a_m_p_l_e_s.

_D_e_s_c_r_i_p_t_i_o_n:

     The 'colorectal' dataset consists: an named vector 'DE_Colorectal'
     , which represents the log2 fold changes of the genes chosen as
     differentially expressed between  colorectal cancer and normal
     samples based on data from Hong et al, 2007, and  the universe of
     all Entrez gene IDs available on the array, 'ALL_Colorectal'.
     These two vectors were obtained starting from the 'top' dataframe
     which is the output from the topTable function of the limma
     package using the RMA processed gene expression data downloaded
     from  GEO (GSE4107). The microarray platform used was Affymetrix
     HGU-133PLUS2.0.

_U_s_a_g_e:

     data(colorectalcancer)

_S_o_u_r_c_e:

     Yi Hong and  Kok Sun Ho and  Kong Weng Eu and  Peh Yean Cheah, A
     susceptibility gene set for early onset colorectal cancer that
     integrates diverse signaling pathways: implication for
     tumorigenesis, Clin Cancer Res, 2007, 13(4),1107-14.

