\HeaderA{sim.intervention}{Simulate interventions in a Nested Effects Model}{sim.intervention}
\keyword{models}{sim.intervention}
\begin{Description}\relax
Simulates a knock-down of a list of network nodes and returns the network nodes and effect reporters, where effects are expected.
\end{Description}
\begin{Usage}
\begin{verbatim}
sim.intervention(x, int)
\end{verbatim}
\end{Usage}
\begin{Arguments}
\begin{ldescription}
\item[\code{x}] nem object
\item[\code{int}] a character vector of nodes in the network
\end{ldescription}
\end{Arguments}
\begin{Value}
list with two slots:
\begin{ldescription}
\item[\code{Sgenes.effected}] effected network nodes
\item[\code{Egenes.effected}] effected downstream effect reporters
\end{ldescription}
\end{Value}
\begin{Author}\relax
Holger Froehlich
\end{Author}
\begin{Examples}
\begin{ExampleCode}
   data("BoutrosRNAi2002")
   D <- BoutrosRNAiDiscrete[,9:16]
   res = nem(D, control=set.default.parameters(unique(colnames(D)), para=c(0.13,0.05))) 
   sim.intervention(res, "rel") # simulate knock-down of rel
\end{ExampleCode}
\end{Examples}

