POSPS {yeastGSData} | R Documentation

## A Platinum Standard Data Set

### Description

While Yu et al. call this a platinum standard data set, it is really a gold standard data set for binary physical interactions.

### Usage

    data(POSPS)

### Format

A data frame with 1867 observations on the following 2 variables.

`ORF1`
  a character vector
`ORF2`
  a character vector

### Details

These data, reported in the paper below, are intended to represent well established binary physical interactions between proteins. This contrasts with the gold standard `MIPSGS` which describes multi-protein complexes.

Ye et al, describe the construction as follows: “ Briefly, the data set contains physical interactions from complex protein structures in the Protein Data Bank (Westbrook et al. 2003), verified interactions from small-scale experiments (Mewes et al. 2000; Xenarios et al. 2002; Bader et al. 2003), and protein pairs from small MIPS catalog complexes (4 or fewer subunits).”

### References

Annotation Transfer Between Genomes: Protein-Protein Interologs and Protein-DNA Regulogs, H. Yu et al, Genome Research, 1107-1118, 2004.

### Examples

    data(POSPS)

[Package yeastGSData version 0.1.1 Index]