hgu2beta7GO2ALLPROBES {hgu2beta7} | R Documentation |
The Gene Ontology (GO) Consortium maintains a controlled vocabulary of defined terms to describe gene products. Each of the terms is assigned a GO id that can be associated with a group of genes directly or indirectly through the children GO ids of the GO id. hgu2beta7GO2ALLPROBES maps GO ids to genes (represented by probe identifiers) that are directly or indirectly mapped to the GO ids by traversing the GO tree.
GO terminologies are presented as a directed acyclic graph with root nodes having more general terms than their children nodes. Therefore, a GO id can be mapped to genes corresponding to the term of that particular GO id as well as genes corresponding to the terms of all the children GO ids.
hgu2beta7GO2ALLPROBES maps a GO id to all the probe ids representing genes mapped by traversing the GO tree. The mapped probe ids are named vectors. Names of the vectors are the evidence codes indicating what kind of evidence is found to support the association between GO ids and genes.
The evidence codes in use include:
IMP - inferred from mutant phenotype
IGI - inferred from genetic interaction
IPI - inferred from physical interaction
ISS - inferred from sequence similarity
IDA - inferred from direct assay
IEP - inferred from expression pattern
IEA - inferred from electronic annotation
TAS - traceable author statement
NAS - non-traceable author statement
ND - no biological data available
IC - inferred by curator
A GO id may be mapped to the same probe id more than once but the evidence code can be different. Mappings between Gene Ontology ids and Gene Ontology terms and other information are available in a separate data package named GO.
Mappings were based on data provided:
LocusLink:ftp://ftp.ncbi.nih.gov/refseq/LocusLink/LL_tmpl.gz. Built: February 16, 2005
Package built Wed Feb 16 23:32:20 2005
ftp://ftp.ncbi.nih.gov/refseq/LocusLink/LL_tmpl.gz
# Convert to a list xx <- as.list(hgu2beta7GO2ALLPROBES) if(length(xx) > 0){ # Gets the probe ids for the top 2nd and 3nd GO ids goids <- xx[2:3] # Gets all the probe ids for the first element of goids goids[[1]] # Evidence code for the mappings names(goids[[1]]) }