hgu2beta7GO2PROBE {hgu2beta7} | R Documentation |
The Gene Ontology (GO) Consortium maintains a controlled vocabulary of defined terms to describe gene products. Each of the terms is assigned a GO id that can be associated with a group of genes. hgu2beta7GO2PROBE maps each GO id to the probe identifiers representing genes that are associated with the GO ids
GO terminologies are presented as a directed acyclic graph with root nodes having more general terms than their children nodes. hgu2beta7GO2PROBE only maps GO ids to probe ids associated with nodes specified by the GO ids but not their children nodes. The mapped probe ids are named vectors. Names of the vectors are the evidence codes indicating what kind of evidence is found to support the association between GO ids and genes.
The evidence codes in use include:
IMP - inferred from mutant phenotype
IGI - inferred from genetic interaction
IPI - inferred from physical interaction
ISS - inferred from sequence similarity
IDA - inferred from direct assay
IEP - inferred from expression pattern
IEA - inferred from electronic annotation
TAS - traceable author statement
NAS - non-traceable author statement
ND - no biological data available
IC - inferred by curator
A GO id may be mapped to the same probe id more than once but the evidence code can be different. Mappings between Gene Ontology ids an Gene Ontology terms and other information are available in a separate data package named GO.
Mappings were based on data provided by:
LocusLink LocusLink:ftp://ftp.ncbi.nih.gov/refseq/LocusLink/LL_tmpl.gz. Built: February 16, 2005.
Package built Wed Feb 16 23:32:20 2005
ftp://ftp.ncbi.nih.gov/refseq/LocusLink/LL_tmpl.gz
# Convert to a list xx <- as.list(hgu2beta7GO2PROBE) if(length(xx) > 0){ # Gets the probe ids for the top 2nd and 3nd GO ids goids <- xx[2:3] # Gets the probe ids for the first element of goids goids[[1]] # Evidence code for the mappings names(goids[[1]]) }