identifymiRTargetsByICPPam50 {miRLAB} | R Documentation |
This function identifies the top miRNA targets by ICP and PAM50.
identifymiRTargetsByICPPam50(d, nmiR, nmR, fiftymRNAsData, top = 1, topk = 500)
d |
A matrix of expression of miRNAs and mRNAs with columns being miRNA or mRNA names and rows being samples |
nmiR |
Number of miRNAs |
nmR |
Number of mRNAs |
fiftymRNAsData |
A matrix of expression of 50 mRNAs in PAM50 with columns being mRNA names and rows being samples |
top |
1 if getting the top of all miRNAs and 2 if getting the top of each miRNA |
topk |
Number of the top to get |
The top k miRNA targets
1. Parker, J. S., et al. (2009). "Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes." Journal of Clinical Oncology 27(8): 1160-1167.