correct.peptide.ratios {isobar}R Documentation

Correct peptide ratios with protein ratios from a separate experiment.

Description

Correct peptide ratios with protein ratios from a separate experiment.

Usage

correct.peptide.ratios(ibspectra, peptide.quant.tbl, protein.quant.tbl,
         protein.group.combined, adjust.variance = TRUE,
         correlation = 0, recalculate.pvalue = TRUE)

Arguments

ibspectra

IBSpectra object.

peptide.quant.tbl

Calculated with peptideRatios.

protein.quant.tbl

Calculated with proteinRatios.

protein.group.combined

ProteinGroup object generated on both PTM and protein data.

adjust.variance

Adjust variance of ratios.

correlation

Assumed correlation between peptide and protein ratios for variance adjustment.

recalculate.pvalue

Recalculate p-value after variance adjustment.

Author(s)

Florian P. Breitwieser


[Package isobar version 1.38.0 Index]