decon.bootstrap {DeconRNASeq} | R Documentation |
A function is used to estimate the the confidence interval for the proportions predicted by deconvolution through bootstrapping.
decon.bootstrap(data.set, possible.signatures, n.sig, n.iter)
data.set |
the data object for mixing samples |
possible.signatures |
a data frame providing the expression values from pure tissue samples |
n.sig |
the number of genes/transcripts used for estimation of proportions from our deconvolution |
n.iter |
the number of bootstraps for our deconvolution |
A three dimentional array to store means and 95% confidence interval
Ting Gong tinggong@gmail.com Joseph D. Szustakowski joseph.szustakowski@novartis.com
Gong, T., et al. (2011) Optimal Deconvolution of Transcriptional Profiling Data Using Quadratic Programming with Application to Complex Clinical Blood Samples, PLoS One, 6, e27156.